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- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
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- Product number
- ABIN615955 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Bone Marrow Stromal Cell Antigen 2 (BST2) (Internal Region) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide with sequence, from the internal region of the protein sequence according to NP_004326.1. Genename: BST2
- Description
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
- Reactivity
- Human
- Host
- Goat
- Antigen sequence
C-ELTEAQKGFQD- Epitope
- Internal Region
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Tetherin inhibits HIV-1 release by directly tethering virions to cells.
A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.
Interferon-alpha enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft models.
Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
Perez-Caballero D, Zang T, Ebrahimi A, McNatt MW, Gregory DA, Johnson MC, Bieniasz PD
Cell 2009 Oct 30;139(3):499-511
Cell 2009 Oct 30;139(3):499-511
A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.
Rollason R, Korolchuk V, Hamilton C, Jepson M, Banting G
The Journal of cell biology 2009 Mar 9;184(5):721-36
The Journal of cell biology 2009 Mar 9;184(5):721-36
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.
Neil SJ, Zang T, Bieniasz PD
Nature 2008 Jan 24;451(7177):425-30
Nature 2008 Jan 24;451(7177):425-30
Interferon-alpha enhances CD317 expression and the antitumor activity of anti-CD317 monoclonal antibody in renal cell carcinoma xenograft models.
Kawai S, Azuma Y, Fujii E, Furugaki K, Ozaki S, Matsumoto T, Kosaka M, Yamada-Okabe H
Cancer science 2008 Dec;99(12):2461-6
Cancer science 2008 Dec;99(12):2461-6
Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T, Ishihara K
Genomics 1995 Apr 10;26(3):527-34
Genomics 1995 Apr 10;26(3):527-34
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- AP23736PU-N BST2 antibody staining of Human Spleen lysate at 0.3 μg/ml (35μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
