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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12369-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12369-1-AP, RRID:AB_2302242
- Product name
- Sortilin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Sortilin antibody (Cat. #12369-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats.
Inductive effect of SORT1 on odontoblastic differentiation of human dental pulp-derived stem cells.
Time-resolved single-cell transcriptomics reveals the landscape and dynamics of hepatic cells in sepsis-induced acute liver dysfunction.
ProBDNF Upregulation in Murine Hind Limb Ischemia Reperfusion Injury: A Driver of Inflammation.
Sortilin acts as an endocytic receptor for α-synuclein fibril.
Age‑related differences for expression of the nerve‑specific proteins after peripheral nerve injury.
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake.
Prions amplify through degradation of the VPS10P sorting receptor sortilin.
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Mapping of the N-linked glycoproteome of human spermatozoa.
Wu Z, Yang Y, Wang M
Journal of orthopaedic surgery and research 2024 Mar 20;19(1):192
Journal of orthopaedic surgery and research 2024 Mar 20;19(1):192
Inductive effect of SORT1 on odontoblastic differentiation of human dental pulp-derived stem cells.
Omagari D, Toriumi T, Tsuda H, Hayatsu M, Watanabe K, Mizutami Y, Honda M, Mikami Y
Differentiation; research in biological diversity 2023 Sep-Oct;133:88-97
Differentiation; research in biological diversity 2023 Sep-Oct;133:88-97
Time-resolved single-cell transcriptomics reveals the landscape and dynamics of hepatic cells in sepsis-induced acute liver dysfunction.
Chen G, Ren C, Xiao Y, Wang Y, Yao R, Wang Q, You G, Lu M, Yan S, Zhang X, Zhang J, Yao Y, Zhou H
JHEP reports : innovation in hepatology 2023 Jun;5(6):100718
JHEP reports : innovation in hepatology 2023 Jun;5(6):100718
ProBDNF Upregulation in Murine Hind Limb Ischemia Reperfusion Injury: A Driver of Inflammation.
Aby K, Antony R, Li Y
Biology 2023 Jun 24;12(7)
Biology 2023 Jun 24;12(7)
Sortilin acts as an endocytic receptor for α-synuclein fibril.
Ishiyama S, Hasegawa T, Sugeno N, Kobayashi J, Yoshida S, Miki Y, Wakabayashi K, Fukuda M, Kawata Y, Nakamura T, Sato K, Ezura M, Kikuchi A, Takeda A, Aoki M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23017
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Jul;37(7):e23017
Age‑related differences for expression of the nerve‑specific proteins after peripheral nerve injury.
Obata H, Naito K, Kikui A, Nakamura S, Suzuki K, Kawakita S, Suzuki T, Goto K, Nagura N, Sugiyama Y, Nagaoka I, Ishijima M
Experimental and therapeutic medicine 2022 Nov;24(5):682
Experimental and therapeutic medicine 2022 Nov;24(5):682
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
Black HL, Livingstone R, Mastick CC, Al Tobi M, Taylor H, Geiser A, Stirrat L, Kioumourtzoglou D, Petrie JR, Boyle JG, Bryant NJ, Gould GW
Journal of cell science 2022 Dec 1;135(1)
Journal of cell science 2022 Dec 1;135(1)
CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis.
Camus SM, Camus MD, Figueras-Novoa C, Boncompain G, Sadacca LA, Esk C, Bigot A, Gould GW, Kioumourtzoglou D, Perez F, Bryant NJ, Mukherjee S, Brodsky FM
The Journal of cell biology 2020 Jan 6;219(1)
The Journal of cell biology 2020 Jan 6;219(1)
Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake.
Xiao Y, Yan W, Lu Y, Zhou K, Cai W
EBioMedicine 2018 Sep;35:133-141
EBioMedicine 2018 Sep;35:133-141
Prions amplify through degradation of the VPS10P sorting receptor sortilin.
Uchiyama K, Tomita M, Yano M, Chida J, Hara H, Das NR, Nykjaer A, Sakaguchi S
PLoS pathogens 2017 Jun;13(6):e1006470
PLoS pathogens 2017 Jun;13(6):e1006470
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Johnson NR, Condello C, Guan S, Oehler A, Becker J, Gavidia M, Carlson GA, Giles K, Prusiner SB
Proceedings of the National Academy of Sciences of the United States of America 2017 Dec 19;114(51):E11029-E11036
Proceedings of the National Academy of Sciences of the United States of America 2017 Dec 19;114(51):E11029-E11036
Mapping of the N-linked glycoproteome of human spermatozoa.
Wang G, Wu Y, Zhou T, Guo Y, Zheng B, Wang J, Bi Y, Liu F, Zhou Z, Guo X, Sha J
Journal of proteome research 2013 Dec 6;12(12):5750-9
Journal of proteome research 2013 Dec 6;12(12):5750-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12369-1-AP(SORT1 antibody) at dilution of 1:1200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Sortilin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Sortilin. This antibody recognizes human,mouse,rat antigen. The Sortilin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
