17513-1-AP

antibody from Proteintech Group

Targeting: KRT7 CK7, K2C7, K7, SCL

Provider product page for 17513-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [42]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunohistochemistry [2]

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Product number: 17513-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17513-1-AP, RRID:AB_2134468
Product name: Cytokeratin 7-specific antibody
Antibody type: Polyclonal
Description: Cytokeratin 7-specific antibody (Cat. #17513-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

KRT7 protein structure - 17513-1-AP shown in red.

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Fibronectin mediates activin A-promoted human trophoblast migration and acquisition of endothelial-like phenotype.

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Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women With Repeated Implantation Failure.

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Endocrinology 2024 Jan 16;165(3)

Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.

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Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.

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Insufficient GDF15 expression predisposes women to unexplained recurrent pregnancy loss by impairing extravillous trophoblast invasion.

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Glucose Regulates Glucose Transport and Metabolism via mTOR Signaling Pathway in Bovine Placental Trophoblast Cells.

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Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.

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European journal of cancer (Oxford, England : 1990) 2022 May;166:208-218

USP13 promotes development and metastasis of high-grade serous ovarian carcinoma in a novel mouse model.

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Elabela: Negative Regulation of Ferroptosis in Trophoblasts via the Ferritinophagy Pathway Implicated in the Pathogenesis of Preeclampsia.

Yang H, Zhang X, Ding Y, Xiong H, Xiang S, Wang Y, Li H, Liu Z, He J, Tao Y, Yang H, Qi H
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miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia.

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Molecular therapy. Nucleic acids 2022 Dec 13;30:143-161

Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.

Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894

Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.

Wang J, Ding J, Zhang S, Chen X, Yan S, Zhang Y, Yin T
Frontiers in immunology 2021;12:717370

Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.

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A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner.

Chen XJ, Wei WF, Wang ZC, Wang N, Guo CH, Zhou CF, Liang LJ, Wu S, Liang L, Wang W
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A Novel Molecule in Human Cyclic Endometrium: LncRNA TUNAR Is Involved in Embryo Implantation.

Wang Y, Hu S, Yao G, Zhu Q, He Y, Lu Y, Qi J, Xu R, Ding Y, Li J, Li X, Sun Y
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FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7.

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Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis.

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The role of ERK-RSK signaling in the proliferation of intrahepatic biliary epithelial cells exposed to microcystin-leucine arginine.

Yan M, Shen G, Zhou Y, Meng X, Han X
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SPARCL1 impedes trophoblast migration and invasion by down-regulating ERK phosphorylation and AP-1 production and altering EMT-related molecule expression.

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Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.

Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
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FasL on decidual macrophages mediates trophoblast apoptosis: A potential cause of recurrent miscarriage.

Ding J, Yin T, Yan N, Cheng Y, Yang J
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Cytokeratin expression in epidermal stem cells in skin adnexal tumors.

Zhou X, Li G, Wang D, Sun X, Li X
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Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.

Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217

AP1 mediates uPA/uPAR induced FUT4 expression and trophoblast invasion.

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Up-regulation of CD81 inhibits cytotrophoblast invasion and mediates maternal endothelial cell dysfunction in preeclampsia.

Shen L, Diao Z, Sun HX, Yan GJ, Wang Z, Li RT, Dai Y, Wang J, Li J, Ding H, Zhao G, Zheng M, Xue P, Liu M, Zhou Y, Hu Y
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 21;114(8):1940-1945

DC - SIGNR by influencing the lncRNA HNRNPKP2 upregulates the expression of CXCR4 in gastric cancer liver metastasis.

Zhang Y, Zhang Q, Zhang M, Yuan M, Wang Z, Zhang J, Zhou X, Zhang Y, Lin F, Na H, Ren S, Zuo Y
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Dong C, Zhang L, Sun R, Liu J, Yin H, Li X, Zheng X, Zeng H
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Leukemia inhibitory factor promote trophoblast invasion via urokinase-type plasminogen activator receptor in preeclampsia.

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Curcumin improves LPS-induced preeclampsia-like phenotype in rat by inhibiting the TLR4 signaling pathway.

Gong P, Liu M, Hong G, Li Y, Xue P, Zheng M, Wu M, Shen L, Yang M, Diao Z, Hu Y
Placenta 2016 May;41:45-52

Resistin reinforces interferon λ-3 to eliminate hepatitis C virus with fine-tuning from RETN single-nucleotide polymorphisms.

Chang ML, Liang KH, Ku CL, Lo CC, Cheng YT, Hsu CM, Yeh CT, Chiu CT
Scientific reports 2016 Aug 1;6:30799

Uterine artery dysfunction in pregnant ACE2 knockout mice is associated with placental hypoxia and reduced umbilical blood flow velocity.

Yamaleyeva LM, Pulgar VM, Lindsey SH, Yamane L, Varagic J, McGee C, daSilva M, Lopes Bonfa P, Gurley SB, Brosnihan KB
American journal of physiology. Endocrinology and metabolism 2015 Jul 1;309(1):E84-94

Low doses of CMV induce autoimmune-mediated and inflammatory responses in bile duct epithelia of regulatory T cell-depleted neonatal mice.

Wen J, Xiao Y, Wang J, Pan W, Zhou Y, Zhang X, Guan W, Chen Y, Zhou K, Wang Y, Shi B, Zhou X, Yuan Z, Cai W
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Pregnancy-associated plasma protein A up-regulated by progesterone promotes adhesion and proliferation of trophoblastic cells.

Wang J, Liu S, Qin HM, Zhao Y, Wang XQ, Yan Q
International journal of clinical and experimental pathology 2014;7(4):1427-37

Noninvasive urine-derived cell lines derived from neurological genetic patients.

Zhang QJ, He J, Ni W, Lin X, Yao XP, Lin MT, Murong SX, Wang N, Chen WJ
Neuroreport 2013 Mar 6;24(4):161-6

Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model.

Noguchi A, Kikuchi K, Ohtsu T, Yoshiwara M, Nakamura Y, Miyagi Y, Zheng H, Takano Y
Oncology reports 2013 Dec;30(6):2603-8

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 17513-1-AP(KRT7-Specific antibody) at dilution of 1:300
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using KRT7 antibody 17513-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 17513-1-AP(KRT7-Specific antibody) at dilution of 1:50 (under 40x lens)
Sample type: tissue