orb386236

antibody from Biorbyt
Targeting: KRT7 CK7, K2C7, K7, SCL
Provider product page for orb386236
Western blot
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb386236 - Provider product page
Provider
Biorbyt
Product name
KRT7 Antibody / Cytokeratin 7
Antibody type
Recombinant
Description
Cytokeratin-7 (CK7) is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK7 is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. It is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain CK7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the protein is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively. It is commonly used together with CK20 when making such diagnoses. [Wiki]
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antibody clone number
KRT7/1499R
Vial size
20 ug
Storage
Store the recombinant Cytokeratin 7 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
KRT7 protein structure - orb386236 shown in red.