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- References [30]
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- Product number
- 11037-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11037-2-AP, RRID:AB_2110650
- Product name
- Glutamine Synthetase antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Glutamine Synthetase antibody (Cat. #11037-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation.
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction.
TRIM9 promotes Müller cell-derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7.
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Loss of hepatic manganese transporter ZIP8 disrupts serum transferrin glycosylation and the glutamate-glutamine cycle.
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Spatially resolved isotope tracing reveals tissue metabolic activity.
Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice.
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells.
An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs.
Metabolomic Study on Nude Mice Models of Gastric Cancer Treated with Modified Si Jun Zi Tang via HILIC UHPLC-Q-TOF/MS Analysis.
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
Androgens regulate follicle stage-dependent pro- and anti-apoptosis in teleost ovaries through ZIP9 activation of different G proteins†.
Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
Long-Term Moderate Exercise Rescues Age-Related Decline in Hippocampal Neuronal Complexity and Memory.
Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis.
High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice.
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice.
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
Optimisation of the quantification of glutamine synthetase and myelin basic protein in cerebrospinal fluid by a combined acidification and neutralisation protocol.
Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.
Zhang KH, Zhang FF, Zhang ZL, Fang KF, Sun WX, Kong N, Wu M, Liu HO, Liu Y, Li Z, Cai QQ, Wang Y, Wei QW, Lin PC, Lin Y, Xu W, Xu CJ, Yuan YY, Zhao SM
Protein & cell 2024 Jul 1;15(7):512-529
Protein & cell 2024 Jul 1;15(7):512-529
SorCS2 is involved in promoting periodontitis-induced depression-like behaviour in mice.
Li Y, Yang Y, Guan X, Liu Z, Pan L, Wang Y, Jia X, Yang J, Hou T
Oral diseases 2024 Apr 3;
Oral diseases 2024 Apr 3;
TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction.
Zhang X, Shao J, Wang C, Liu C, Hao H, Li X, An Y, He J, Zhao W, Zhao Y, Kong Y, Jia Z, Wan S, Yuan Y, Zhang H, Zhang H, Du X
Cell reports 2024 Apr 23;43(4):114014
Cell reports 2024 Apr 23;43(4):114014
TRIM9 promotes Müller cell-derived retinal stem cells to differentiate into retinal ganglion cells by regulating Atoh7.
Zeng Q, Zhou J, Hua X
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):586-595
In vitro cellular & developmental biology. Animal 2023 Sep;59(8):586-595
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O-GlcNAcylation via microbiota-derived acetate.
Zhou P, Chang WY, Gong DA, Xia J, Chen W, Huang LY, Liu R, Liu Y, Chen C, Wang K, Tang N, Huang AL
Cell metabolism 2023 Nov 7;35(11):1961-1975.e6
Cell metabolism 2023 Nov 7;35(11):1961-1975.e6
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Tang XH, Diao YG, Ren ZY, Zang YY, Zhang GF, Wang XM, Duan GF, Shen JC, Hashimoto K, Zhou ZQ, Yang JJ
Neuropharmacology 2023 Mar 1;225:109383
Neuropharmacology 2023 Mar 1;225:109383
Loss of hepatic manganese transporter ZIP8 disrupts serum transferrin glycosylation and the glutamate-glutamine cycle.
Powers M, Minchella D, Gonzalez-Acevedo M, Escutia-Plaza D, Wu J, Heger C, Milne G, Aschner M, Liu Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2023 Jul;78:127184
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2023 Jul;78:127184
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Ai C, Sun X, Xiao S, Guo L, Shang M, Shi D, Meng D, Zhao Y, Wang X, Li J
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Spatially resolved isotope tracing reveals tissue metabolic activity.
Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM
Nature methods 2022 Feb;19(2):223-230
Nature methods 2022 Feb;19(2):223-230
Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH.
Zhou P, Xu Y, Yang L, Meng P, Guo J, Liu Z, Jin B, Xie K, Zhu H, Du L, Jin X
Journal of molecular histology 2022 Dec;53(6):947-954
Journal of molecular histology 2022 Dec;53(6):947-954
Urea as a By-Product of Ammonia Metabolism Can Be a Potential Serum Biomarker of Hepatocellular Carcinoma.
Bai C, Wang H, Dong D, Li T, Yu Z, Guo J, Zhou W, Li D, Yan R, Wang L, Wang Z, Li Y, Ren L
Frontiers in cell and developmental biology 2021;9:650748
Frontiers in cell and developmental biology 2021;9:650748
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Guo Y, Cang X, Zhu L, Zhu M, Li A, Wang Z, Zhang Y, Wang X, Song E
Experimental eye research 2021 Sep;210:108703
Experimental eye research 2021 Sep;210:108703
Enhanced Contextual Fear Memory and Elevated Astroglial Glutamate Synthase Activity in Hippocampal CA1 BChE shRNA Knockdown Mice.
Chen S, Lin Z, Tan KL, Chen R, Su W, Zhao H, Tan Q, Tan W
Frontiers in psychiatry 2020;11:564843
Frontiers in psychiatry 2020;11:564843
Eurocristatine, a plant alkaloid from Eurotium cristatum, alleviates insulin resistance in db/db diabetic mice via activation of PI3K/AKT signaling pathway.
Zhang H, Hui J, Yang J, Deng J, Fan D
European journal of pharmacology 2020 Nov 15;887:173557
European journal of pharmacology 2020 Nov 15;887:173557
Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.
Wang Z, Cai L, Li H, Liang M, Zhang Y, Wu Q, Yang L
Journal of food biochemistry 2020 May;44(5):e13180
Journal of food biochemistry 2020 May;44(5):e13180
Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.
Li H, Liang M, Wang Z, Zhang Y, Wu Q, Yang L
Journal of medicinal food 2020 Jun;23(6):565-574
Journal of medicinal food 2020 Jun;23(6):565-574
α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells.
Lesner NP, Gokhale AS, Kota K, DeBerardinis RJ, Mishra P
Metabolic engineering 2020 Jul;60:157-167
Metabolic engineering 2020 Jul;60:157-167
An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs.
Li WJ, Zhu XJ, Yuan TJ, Wang ZY, Bian ZQ, Jing HS, Shi X, Chen CY, Fu GB, Huang WJ, Shi YP, Liu Q, Zeng M, Zhang HD, Wu HP, Yu WF, Zhai B, Yan HX
Science translational medicine 2020 Jul 8;12(551)
Science translational medicine 2020 Jul 8;12(551)
Metabolomic Study on Nude Mice Models of Gastric Cancer Treated with Modified Si Jun Zi Tang via HILIC UHPLC-Q-TOF/MS Analysis.
Nie S, Zhao Y, Qiu X, Wang W, Yao Y, Yi M, Wang D
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3817879
Evidence-based complementary and alternative medicine : eCAM 2019;2019:3817879
Elevated levels of circulating ITIH4 are associated with hepatocellular carcinoma with nonalcoholic fatty liver disease: from pig model to human study.
Nakamura N, Hatano E, Iguchi K, Sato M, Kawaguchi H, Ohtsu I, Sakurai T, Aizawa N, Iijima H, Nishiguchi S, Tomono T, Okuda Y, Wada S, Seo S, Taura K, Uemoto S, Ikegawa M
BMC cancer 2019 Jun 25;19(1):621
BMC cancer 2019 Jun 25;19(1):621
Androgens regulate follicle stage-dependent pro- and anti-apoptosis in teleost ovaries through ZIP9 activation of different G proteins†.
Converse A, Thomas P
Biology of reproduction 2019 Aug 1;101(2):377-391
Biology of reproduction 2019 Aug 1;101(2):377-391
Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
Fan S, Xian X, Li L, Yao X, Hu Y, Zhang M, Li W
Journal of Alzheimer's disease : JAD 2018;66(4):1731-1743
Journal of Alzheimer's disease : JAD 2018;66(4):1731-1743
Long-Term Moderate Exercise Rescues Age-Related Decline in Hippocampal Neuronal Complexity and Memory.
Tsai SF, Ku NW, Wang TF, Yang YH, Shih YH, Wu SY, Lee CW, Yu M, Yang TT, Kuo YM
Gerontology 2018;64(6):551-561
Gerontology 2018;64(6):551-561
Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis.
Han Q, Ma Y, Wang H, Dai Y, Chen C, Liu Y, Jing L, Sun X
Journal of translational medicine 2018 Jul 20;16(1):201
Journal of translational medicine 2018 Jul 20;16(1):201
High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice.
Tsai SF, Wu HT, Chen PC, Chen YW, Yu M, Wang TF, Wu SY, Tzeng SF, Kuo YM
Brain research 2018 Dec 1;1700:66-77
Brain research 2018 Dec 1;1700:66-77
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cai WF, Zhang C, Wu YQ, Zhuang G, Ye Z, Zhang CS, Lin SC
Cell research 2018 Aug;28(8):865-867
Cell research 2018 Aug;28(8):865-867
Cerebral level of vGlut1 is increased and level of glycine is decreased in TgSwDI mice.
Timmer NM, Metaxas A, van der Stelt I, Kluijtmans LA, van Berckel BN, Verbeek MM
Journal of Alzheimer's disease : JAD 2014;39(1):89-101
Journal of Alzheimer's disease : JAD 2014;39(1):89-101
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
Liu W, Le A, Hancock C, Lane AN, Dang CV, Fan TW, Phang JM
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 5;109(23):8983-8
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 5;109(23):8983-8
Optimisation of the quantification of glutamine synthetase and myelin basic protein in cerebrospinal fluid by a combined acidification and neutralisation protocol.
Herbert MK, Kuiperij HB, Verbeek MM
Journal of immunological methods 2012 Jul 31;381(1-2):1-8
Journal of immunological methods 2012 Jul 31;381(1-2):1-8
Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.
López-Terrada D, Gunaratne PH, Adesina AM, Pulliam J, Hoang DM, Nguyen Y, Mistretta TA, Margolin J, Finegold MJ
Human pathology 2009 Jun;40(6):783-94
Human pathology 2009 Jun;40(6):783-94
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 11037-2-AP(GLUL antibody) at dilution of 1:100
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Glutamine synthetase antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Glutamine synthetase. This antibody recognizes human, mouse, rat antigen. The Glutamine synthetase antibody has been validated for the following applications: ELISA, WB, IHC analysis.
