Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN500361 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tachykinin Receptor 3 (TACR3) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- NK3R antibody was raised against a 18 amino acid peptide from near the center of humanNK3R.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references Tachykinin NK3 receptor contribution to systemic release of vasopressin and oxytocin in response to osmotic and hypotensive challenge.
Neurokinin B receptor (NK3)-containing neurons in the paraventricular and supraoptic nuclei of the rat hypothalamus synthesize vasopressin and express Fos following intravenous injection of hypertonic saline.
The mammalian tachykinin receptors.
Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells.
Haley GE, Flynn FW
American journal of physiology. Regulatory, integrative and comparative physiology 2007 Aug;293(2):R931-7
American journal of physiology. Regulatory, integrative and comparative physiology 2007 Aug;293(2):R931-7
Neurokinin B receptor (NK3)-containing neurons in the paraventricular and supraoptic nuclei of the rat hypothalamus synthesize vasopressin and express Fos following intravenous injection of hypertonic saline.
Ding YQ, Lü BZ, Guan ZL, Wang DS, Xu JQ, Li JH
Neuroscience 1999;91(3):1077-85
Neuroscience 1999;91(3):1077-85
The mammalian tachykinin receptors.
Maggi CA
General pharmacology 1995 Sep;26(5):911-44
General pharmacology 1995 Sep;26(5):911-44
Direct linkage of three tachykinin receptors to stimulation of both phosphatidylinositol hydrolysis and cyclic AMP cascades in transfected Chinese hamster ovary cells.
Nakajima Y, Tsuchida K, Negishi M, Ito S, Nakanishi S
The Journal of biological chemistry 1992 Feb 5;267(4):2437-42
The Journal of biological chemistry 1992 Feb 5;267(4):2437-42
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of NK3R in RAW264.7 cell lysate with AP30602PU-N at (A) 0.5 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of NK3R in human brain tissue with AP30602PU-N at 5 ?g/ml.