Explore
Validate
Learn
Western blot
Immunocytochemistry
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [27]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN152344 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Canine, Simian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- A180
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Nrf2-Inducers Counteract Neurodegeneration in Frataxin-Silenced Motor Neurons: Disclosing New Therapeutic Targets for Friedreich's Ataxia.
The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues.
Capillarisin augments anti-oxidative and anti-inflammatory responses by activating Nrf2/HO-1 signaling.
Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer's Disease: A Rational Approach.
Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells.
Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy.
Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling.
Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice.
Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation.
GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.
Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cells.
Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.
Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system.
Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.
Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance.
Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease.
Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity.
Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells.
Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury.
trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors.
5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo.
Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.
Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1.
Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues.
Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors.
Immortalisation of a human diploid fibroblast cell strain: a DT-diaphorase paradox.
Petrillo S, Piermarini E, Pastore A, Vasco G, Schirinzi T, Carrozzo R, Bertini E, Piemonte F
International journal of molecular sciences 2017 Oct 18;18(10)
International journal of molecular sciences 2017 Oct 18;18(10)
The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues.
Shrishrimal S, Kosmacek EA, Chatterjee A, Tyson MJ, Oberley-Deegan RE
Antioxidants (Basel, Switzerland) 2017 Nov 6;6(4)
Antioxidants (Basel, Switzerland) 2017 Nov 6;6(4)
Capillarisin augments anti-oxidative and anti-inflammatory responses by activating Nrf2/HO-1 signaling.
Kim J, Lim J, Kang BY, Jung K, Choi HJ
Neurochemistry international 2017 May;105:11-20
Neurochemistry international 2017 May;105:11-20
Targeting the Nrf2/Amyloid-Beta Liaison in Alzheimer's Disease: A Rational Approach.
Simoni E, Serafini MM, Caporaso R, Marchetti C, Racchi M, Minarini A, Bartolini M, Lanni C, Rosini M
ACS chemical neuroscience 2017 Jul 19;8(7):1618-1627
ACS chemical neuroscience 2017 Jul 19;8(7):1618-1627
Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells.
Zhang T, Hu Q, Shi L, Qin L, Zhang Q, Mi M
PloS one 2016;11(12):e0167020
PloS one 2016;11(12):e0167020
Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy.
Qin T, Du R, Huang F, Yin S, Yang J, Qin S, Cao W
Free radical biology & medicine 2016 Mar;92:90-99
Free radical biology & medicine 2016 Mar;92:90-99
Sinomenine attenuates renal fibrosis through Nrf2-mediated inhibition of oxidative stress and TGFβ signaling.
Qin T, Yin S, Yang J, Zhang Q, Liu Y, Huang F, Cao W
Toxicology and applied pharmacology 2016 Aug 1;304:1-8
Toxicology and applied pharmacology 2016 Aug 1;304:1-8
Cranberry extract-enriched diets increase NAD(P)H:quinone oxidoreductase and catalase activities in obese but not in nonobese mice.
Boušová I, Bártíková H, Matoušková P, Lněničková K, Zappe L, Valentová K, Szotáková B, Martin J, Skálová L
Nutrition research (New York, N.Y.) 2015 Oct;35(10):901-909
Nutrition research (New York, N.Y.) 2015 Oct;35(10):901-909
Nrf2 is essential for the anti-inflammatory effect of carbon monoxide in LPS-induced inflammation.
Qin S, Du R, Yin S, Liu X, Xu G, Cao W
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 Jul;64(7):537-48
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2015 Jul;64(7):537-48
GRP78 suppresses lipid peroxidation and promotes cellular antioxidant levels in glial cells following hydrogen peroxide exposure.
Suyama K, Watanabe M, Sakabe K, Otomo A, Okada Y, Terayama H, Imai T, Mochida J
PloS one 2014;9(1):e86951
PloS one 2014;9(1):e86951
Estrogen receptor and PI3K/Akt signaling pathway involvement in S-(-)equol-induced activation of Nrf2/ARE in endothelial cells.
Zhang T, Liang X, Shi L, Wang L, Chen J, Kang C, Zhu J, Mi M
PloS one 2013;8(11):e79075
PloS one 2013;8(11):e79075
Histone deacetylase inhibition activates transcription factor Nrf2 and protects against cerebral ischemic damage.
Wang B, Zhu X, Kim Y, Li J, Huang S, Saleem S, Li RC, Xu Y, Dore S, Cao W
Free radical biology & medicine 2012 Mar 1;52(5):928-36
Free radical biology & medicine 2012 Mar 1;52(5):928-36
Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system.
Gao M, Singh A, Macri K, Reynolds C, Singhal V, Biswal S, Spannhake EW
Respiratory research 2011 Jul 13;12:92
Respiratory research 2011 Jul 13;12:92
Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.
Solis LM, Behrens C, Dong W, Suraokar M, Ozburn NC, Moran CA, Corvalan AH, Biswal S, Swisher SG, Bekele BN, Minna JD, Stewart DJ, Wistuba II
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Jul 15;16(14):3743-53
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Jul 15;16(14):3743-53
Effect of tumor necrosis factor-alpha on estrogen metabolism and endometrial cells: potential physiological and pathological relevance.
Salama SA, Kamel MW, Diaz-Arrastia CR, Xu X, Veenstra TD, Salih S, Botting SK, Kumar R
The Journal of clinical endocrinology and metabolism 2009 Jan;94(1):285-93
The Journal of clinical endocrinology and metabolism 2009 Jan;94(1):285-93
Antiviral activity of Nrf2 in a murine model of respiratory syncytial virus disease.
Cho HY, Imani F, Miller-DeGraff L, Walters D, Melendi GA, Yamamoto M, Polack FP, Kleeberger SR
American journal of respiratory and critical care medicine 2009 Jan 15;179(2):138-50
American journal of respiratory and critical care medicine 2009 Jan 15;179(2):138-50
Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity.
Malhotra D, Thimmulappa R, Vij N, Navas-Acien A, Sussan T, Merali S, Zhang L, Kelsen SG, Myers A, Wise R, Tuder R, Biswal S
American journal of respiratory and critical care medicine 2009 Dec 15;180(12):1196-207
American journal of respiratory and critical care medicine 2009 Dec 15;180(12):1196-207
Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells.
Li CQ, Kim MY, Godoy LC, Thiantanawat A, Trudel LJ, Wogan GN
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 25;106(34):14547-51
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 25;106(34):14547-51
Dietary flaxseed enhances antioxidant defenses and is protective in a mouse model of lung ischemia-reperfusion injury.
Lee JC, Bhora F, Sun J, Cheng G, Arguiri E, Solomides CC, Chatterjee S, Christofidou-Solomidou M
American journal of physiology. Lung cellular and molecular physiology 2008 Feb;294(2):L255-65
American journal of physiology. Lung cellular and molecular physiology 2008 Feb;294(2):L255-65
trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors.
Slitt AL, Cherrington NJ, Dieter MZ, Aleksunes LM, Scheffer GL, Huang W, Moore DD, Klaassen CD
Molecular pharmacology 2006 May;69(5):1554-63
Molecular pharmacology 2006 May;69(5):1554-63
5-Methoxy-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]indole-4,7-dione, a mechanism-based inhibitor of NAD(P)H:quinone oxidoreductase 1, exhibits activity against human pancreatic cancer in vitro and in vivo.
Dehn DL, Siegel D, Zafar KS, Reigan P, Swann E, Moody CJ, Ross D
Molecular cancer therapeutics 2006 Jul;5(7):1702-9
Molecular cancer therapeutics 2006 Jul;5(7):1702-9
Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population.
Zhang J, Schulz WA, Li Y, Wang R, Zotz R, Wen D, Siegel D, Ross D, Gabbert HE, Sarbia M
Carcinogenesis 2003 May;24(5):905-9
Carcinogenesis 2003 May;24(5):905-9
Interaction of human NAD(P)H:quinone oxidoreductase 1 (NQO1) with the tumor suppressor protein p53 in cells and cell-free systems.
Anwar A, Dehn D, Siegel D, Kepa JK, Tang LJ, Pietenpol JA, Ross D
The Journal of biological chemistry 2003 Mar 21;278(12):10368-73
The Journal of biological chemistry 2003 Mar 21;278(12):10368-73
Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1.
Siegel D, Anwar A, Winski SL, Kepa JK, Zolman KL, Ross D
Molecular pharmacology 2001 Feb;59(2):263-8
Molecular pharmacology 2001 Feb;59(2):263-8
Immunodetection of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human tissues.
Siegel D, Ross D
Free radical biology & medicine 2000 Aug;29(3-4):246-53
Free radical biology & medicine 2000 Aug;29(3-4):246-53
Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors.
Siegel D, Franklin WA, Ross D
Clinical cancer research : an official journal of the American Association for Cancer Research 1998 Sep;4(9):2065-70
Clinical cancer research : an official journal of the American Association for Cancer Research 1998 Sep;4(9):2065-70
Immortalisation of a human diploid fibroblast cell strain: a DT-diaphorase paradox.
Kuehl BL, Brezden CB, Traver RD, Siegel D, Ross D, Renzing J, Rauth AM
The British journal of cancer. Supplement 1996 Jul;27:S19-22
The British journal of cancer. Supplement 1996 Jul;27:S19-22
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
