abx015946

antibody from Abbexa

Targeting: NQO1 DHQU, DIA4, DTD, NMOR1, QR1

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx015946

Provider

Abbexa

Product name

NAD(P)H Dehydrogenase [quinone] 1 (NQO1) Antibody

Antibody type

Monoclonal

Description

This gene is a member of the NAD (P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase.This FAD-binding protein forms homodimers and reduces quinones to hydroquinones.This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer.Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.