66489-1-Ig

antibody from Proteintech Group

Targeting: S100A4 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98

Provider product page for 66489-1-Ig

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Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
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Product number: 66489-1-Ig - Provider product page
Provider: Proteintech Group
Product name: S100A4 antibody
Antibody type: Monoclonal
Description: KD/KO validated S100A4 antibody (Cat. #66489-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 2G11B4
Vial size: 20ul, 150ul

S100A4 protein structure - 66489-1-Ig shown in red.

Submitted references S100A4 reprofiles lipid metabolism in mast cells via RAGE and PPAR-γ signaling pathway.

Shihui M, Shirong Y, Jing L, Jingjing H, Tongqian W, Tian T, Chenyu W, Fang Y
International immunopharmacology 2024 Feb 15;128:111555

Immunocompetent mouse models revealed that S100A4(+) monocytes/macrophages facilitate long-term Zika virus infection in the testes.

Yang W, Zhang C, Liu LB, Bian ZZ, Chang JT, Fan DY, Gao N, Wang PG, An J
Emerging microbes & infections 2024 Dec;13(1):2300466

TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.

Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753

Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies.

Julian CG, Houck JA, Fallahi S, Lazo-Vega L, Matarazzo CJ, Diamond B, Miranda-Garrido V, Krause BJ, Moore LG, Shortt JA, Toledo-Jaldin L, Lorca RA
Physiological genomics 2023 Sep 1;55(9):357-367

MicroRNA 9 Is a Regulator of Endothelial to Mesenchymal Transition in Diabetic Retinopathy.

Wang E, Feng B, Chakrabarti S
Investigative ophthalmology & visual science 2023 Jun 1;64(7):13

LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway.

Wu M, Li T, Li G, Niu B, Wu T, Yan L, Wang S, He S, Huang C, Tong W, Li N, Jiang J
European journal of pharmacology 2023 Jul 5;950:175732

C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.

Yang LX, Zhang CT, Yang MY, Zhang XH, Liu HC, Luo CH, Jiang Y, Wang ZM, Yang ZY, Shi ZP, Yang YC, Wei RQ, Zhou L, Mi J, Zhou AW, Yao ZR, Xia L, Yan JS, Lu Y
Blood 2023 Feb 16;141(7):766-786

Neuropilin 1 promotes unilateral ureteral obstruction-induced renal fibrosis via RACK1 in renal tubular epithelial cells.

Hou L, Du Y
American journal of physiology. Renal physiology 2023 Dec 1;325(6):F870-F884

Plk1 promotes renal tubulointerstitial fibrosis by targeting autophagy/lysosome axis.

Du Y, Shang Y, Qian Y, Guo Y, Chen S, Lin X, Cao W, Tang X, Zhou A, Huang S, Zhang A, Jia Z, Zhang Y
Cell death & disease 2023 Aug 29;14(8):571

ADAM17 knockdown mitigates while ADAM17 overexpression aggravates cardiac fibrosis and dysfunction via regulating ACE2 shedding and myofibroblast transformation.

Cheng J, Xue F, Cheng C, Sui W, Zhang M, Qiao L, Ma J, Ji X, Chen W, Yu X, Xi B, Xu F, Su G, Zhao Y, Hao P, Zhang Y, Zhang C
Frontiers in pharmacology 2022;13:997916

Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.

Guo Z, Geng M, Huang Y, Han G, Jing R, Lin C, Zhang X, Zhang M, Fan G, Wang F, Yin H
Cell death and differentiation 2022 Oct;29(10):1928-1940

FGF-2 signaling in nasopharyngeal carcinoma modulates pericyte-macrophage crosstalk and metastasis.

Wang Y, Sun Q, Ye Y, Sun X, Xie S, Zhan Y, Song J, Fan X, Zhang B, Yang M, Lv L, Hosaka K, Yang Y, Nie G
JCI insight 2022 May 23;7(10)

A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma.

Inukai M, Yokoi A, Ishizuka Y, Hashimura M, Matsumoto T, Oguri Y, Nakagawa M, Ishibashi Y, Ito T, Kumabe T, Saegusa M
Cell communication and signaling : CCS 2022 Apr 7;20(1):46

Usp22 Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice.

Kuang X, McAndrew MJ, Mustachio LM, Chen YC, Atanassov BS, Lin K, Lu Y, Shen J, Salinger A, Macatee T, Dent SYR, Koutelou E
Cancers 2021 Aug 25;13(17)

Polydatin inhibits ZEB1-invoked epithelial-mesenchymal transition in fructose-induced liver fibrosis.

Zhao X, Yang Y, Yu H, Wu W, Sun Y, Pan Y, Kong L
Journal of cellular and molecular medicine 2020 Nov;24(22):13208-13222

S100A4/Nonmuscle Myosin IIA/p53 Axis Contributes to Aggressive Features in Ovarian High-Grade Serous Carcinoma.

Hiruta A, Oguri Y, Yokoi A, Matsumoto T, Oda Y, Tomohiro M, Hashimura M, Jiang Z, Tochimoto M, Nakagawa M, Saegusa M
The American journal of pathology 2020 Nov;190(11):2304-2316

S100A4+ macrophages facilitate zika virus invasion and persistence in the seminiferous tubules via interferon-gamma mediation.

Yang W, Wu YH, Liu SQ, Sheng ZY, Zhen ZD, Gao RQ, Cui XY, Fan DY, Qin ZH, Zheng AH, Wang PG, An J
PLoS pathogens 2020 Dec;16(12):e1009019

TGF-β-mediated upregulation of brachyury contributes to constitutively up-regulated type I collagen expression in skin fibroblasts: possible role in systemic sclerosis.

Teng L, Yao G, Gao R, Wang Y, Lin W, Jin Y, Wang Y, Chen H, Wang Z, Chen J
European journal of dermatology : EJD 2019 Aug 1;29(4):359-365

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