16105-1-AP

antibody from Proteintech Group

Targeting: S100A4 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98

Provider product page for 16105-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [81]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

Submit

Product number: 16105-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#16105-1-AP, RRID:AB_11042591
Product name: S100A4 antibody
Antibody type: Polyclonal
Description: KD/KO validated S100A4 antibody (Cat. #16105-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

S100A4 protein structure - 16105-1-AP shown in red.

Submitted references Myeloid-Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis.

Zhou M, Xiao Y, Xu Z, Yang C, Li J, Liu Y, Yin P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 25;:e19267

S100A4 triggeres the pyroptosis of vsmcs: association with mitochondrial damage, impaired mitophagy, and Ca(2+) dysregulation.

Huang J, Zhou B, Wang L, Huang Q, Lin X, Zhao H, Xia Y
Biology direct 2026 Jan 12;21(1):18

Programmed cell death signatures-driven microglial transformation in Alzheimer's disease: single-cell transcriptomics and functional validation.

Li MM, Yang YX, Huang YL, Wu SJ, Huang WL, Ye LC, Xu YY
Frontiers in immunology 2025;16:1610717

An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.

Li Y, Zhai Y, Wang T, Wang S, Tian Y, Bian Z, Zhang Y, Zhang C, Liu M, Li C
Theranostics 2025;15(9):3877-3899

Deciphering the tumor ecosystem dynamics undergoing immunochemotherapy therapy across multiple cancer types unveils the immunosuppressive role of S100A4 in fibroblasts by promoting PD-L1 expression in tumor cells.

Yang B, Chen R, Zu M, Yao J, Ren H, Lin Y, Zhang B, Ji T, Liu Y
Frontiers in cell and developmental biology 2025;13:1613296

Cancer-associated fibroblast derived CXCL14 drives cisplatin chemoresistance by enhancing nucleotide excision repair in bladder cancer.

Li T, Zhu K, Tong H, Sun Y, Zhu J, Qin Z, Chen J, Wu L, Zhang X, Wang A, Gou X, Yin H, He W
Journal of experimental & clinical cancer research : CR 2025 Sep 2;44(1):265

Carcinoma-associated fibroblast-derived exosomes lncRNA RORA-AS1 facilitates radiotherapy resistance of oral squamous cell carcinoma through the IFITM1/STAT axis.

Li L, Ye P, Li G, Xie T, Zha C, Wang Z, He D, Sun C
Biochimica et biophysica acta. Molecular cell research 2025 Oct;1872(7):120015

TGF-β1 mediates epithelial-mesenchymal transition in interstitial cystitis through the regulation of ROCK.

Long X, Yu B, Chen M, Zhang Q, Wang Y, Huang Y, Wu J, Cen P, Lan H, Long J, Zhang Z, Zhong J, Duan X, Yu Q, Gu D
European journal of pharmacology 2025 Nov 5;1006:178184

Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.

Xu C, Pan Y, Zhang S, Lin M, Liu H, Yu Z
Journal of translational medicine 2025 Nov 24;23(1):1341

Inhibition of S100A4 decreases neurotoxic astrocyte reactivity and attenuates neuropathic pain via the TLR4/NF-κB pathway in a rat model of spinal nerve ligation.

Xue T, Song Y, Zhao J, Fan G, Liu Z
The journal of headache and pain 2025 May 1;26(1):97

S100A4 mediates the accumulation and functions of myeloid-derived suppressor cells via GP130/JAK2/STAT3 signaling in acute myeloid leukemia.

Peng Y, Zhang J, Zhang T, Wang C, Bai J, Li Y, Duan J, Fan D, Fu W, Liang X, Xie X, Qi X, Hong W, He Y, Wu C, Zhou J, Chen P, Zeng H, Dai Y, Yu W, Bai H, Guo P, Zeng Z, Zhang Q
Biochimica et biophysica acta. Molecular basis of disease 2025 Jan;1871(1):167498

Qianyang Yuyin granules alleviate hypertension-induced vascular remodeling by inhibiting the phenotypic switch of vascular smooth muscle cells.

Fan Y, Jialiken D, Zheng Z, Zhang W, Zhang S, Zheng Y, Sun Z, Zhang H, Yan X, Liu M, Fang Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):118896

Mechanistic role of the ILK-S100A4 axis in modulating invasion and EMT in salivary adenoid cystic carcinoma.

Yang Y, Luo JX, Li YY, Guo KH, Ye L, Zhao D
Oncology letters 2025 Dec;30(6):597

Missegregation of Chromosome 3 and Generation of Monosomy 3 in the Proliferating Uveal Melanoma Cells Under Hyperglycemia.

Tura A, Sonntag SR, von Bubnoff NCC, Spielmann M, Grisanti S
Investigative ophthalmology & visual science 2025 Dec 1;66(15):10

Integrated Analysis of Lactate-Related Genes Identifies S100A4 as a Novel Marker Promoting the Migration and Invasion of Endometrial Stromal Cell in Endometriosis.

Wang X, Chen Y, Wu Q, Wang X, Wu Y, Liu H
Reproductive sciences (Thousand Oaks, Calif.) 2025 Aug;32(8):2558-2573

Mesenteric adipose-derived exosomal TINAGL1 enhances intestinal fibrosis in Crohn's Disease via SMAD4.

Chen Y, Li J, Zhang X, Li S, Cheng Y, Fu X, Li J, Zhu L
Journal of advanced research 2025 Apr;70:139-158

Recombinant Humanized Collagen: A Promising Treatment for Pelvic Organ Prolapse via Enhanced Fibroblast Function and Angiogenesis.

Zhang Y, Li Y, Wu X, Wang S, Wei X, Sun X
International urogynecology journal 2025 Apr;36(4):881-893

Multimodal fusion of radio-pathology and proteogenomics identify integrated glioma subtypes with prognostic and therapeutic opportunities.

Liu Z, Wu Y, Xu H, Wang M, Weng S, Pei D, Chen S, Wang W, Yan J, Cui L, Duan J, Zhao Y, Wang Z, Ma Z, Li R, Duan W, Qiu Y, Su D, Li S, Liu H, Li W, Ma C, Yu M, Yu Y, Chen T, Fu J, Zhen Y, Yu B, Ji Y, Zheng H, Liang D, Liu X, Yan D, Han X, Wang F, Li ZC, Zhang Z
Nature communications 2025 Apr 13;16(1):3510

The Mechanism of Catalpol to Improve Oxidative Damage of Dermal Fibroblasts Based on Nrf2/HO-1 Signaling Pathway.

Lang X, Xu L, Li L, Feng X
Drug design, development and therapy 2024;18:2287-2297

S100A10 promotes cancer metastasis via recruitment of MDSCs within the lungs.

Li J, Zhou C, Gao X, Tan T, Zhang M, Li Y, Chen H, Wang R, Wang B, Liu J, Liu P
Oncoimmunology 2024;13(1):2381803

Long noncoding RNA VPS9D1-AS1 promotes the progression of endometrial cancer via regulation of the miR-187-3p/S100A4 axis.

Ren W, Ouyang L
Environmental toxicology 2024 Sep;39(9):4447-4458

Spatial resolved transcriptomics reveals distinct cross-talk between cancer cells and tumor-associated macrophages in intrahepatic cholangiocarcinoma.

Dong ZR, Zhang MY, Qu LX, Zou J, Yang YH, Ma YL, Yang CC, Cao XL, Wang LY, Zhang XL, Li T
Biomarker research 2024 Sep 11;12(1):100

Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1.

Gao P, Lu Y, Tang K, Wang W, Wang T, Zhu Y, Zhao J, Mao Y
Journal of translational medicine 2024 Nov 21;22(1):1051

Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis.

Wang YH, Gao P, Wang YQ, Xu LZ, Zeng KW, Tu PF
European journal of pharmacology 2024 Jun 5;972:176551

Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.

Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R
Molecular cancer research : MCR 2024 Jun 4;22(6):538-554

Potential Involvement of M1 Macrophage and VLA4/VCAM-1 Pathway in the Valvular Damage Due to Rheumatic Heart Disease.

Xian S, Li Y, Bai L, Tang S, Meng Z, Wen H, Huang F, Zeng Z
Frontiers in bioscience (Landmark edition) 2024 Jun 18;29(6):219

CXCL3/TGF-β-mediated crosstalk between CAFs and tumor cells augments RCC progression and sunitinib resistance.

Wang Y, Ding W, Hao W, Gong L, Peng Y, Zhang J, Qian Z, Xu K, Cai W, Gao Y
iScience 2024 Jul 19;27(7):110224

Dangui Huoxue Preparation (DHP) Ameliorates Skin Fibrosis, Inflammation, and Vasculopathy in the Bleomycin-Induced Murine Model of Systemic Sclerosis.

Yan Y, Cao D, Liang J, Yang Q, Gao D, Shen C, Hu F, Li Z, Han Y, Cao X, Wang Q
Advanced biology 2024 Jan;8(1):e2300315

Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.

Adzraku SY, Cao C, Zhou Q, Yuan K, Hao X, Li Y, Yuan S, Huang Y, Xu K, Qiao J, Ju W, Zeng L
Cell death & disease 2024 Feb 21;15(2):159

S100A4/NF-κB axis mediates the anticancer effect of epigallocatechin-3-gallate in platinum-resistant ovarian cancer.

Li X, Hou Y, Han G, Yang Y, Wang S, Lv X, Gao M
iScience 2024 Feb 16;27(2):108885

S100A4 reprofiles lipid metabolism in mast cells via RAGE and PPAR-γ signaling pathway.

Shihui M, Shirong Y, Jing L, Jingjing H, Tongqian W, Tian T, Chenyu W, Fang Y
International immunopharmacology 2024 Feb 15;128:111555

Drug-coated balloon therapy for in-stent restenosis in patients with iliofemoral deep vein thrombosis: A single-arm observational study.

Lei J, Pu H, Zhang L, Zeng C, Peng Z, Wu Z, Jiang Y, Wang R, Lu X
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2024 Apr;103(5):752-757

DNMT3A-mediated epigenetic silencing of SOX17 contributes to endothelial cell migration and fibroblast activation in wound healing.

Yu X, Ma X, Zhou J
PloS one 2023;18(10):e0292684

NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.

Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283

Liver fibrosis therapy based on biomimetic nanoparticles which deplete activated hepatic stellate cells.

Xia S, Liu Z, Cai J, Ren H, Li Q, Zhang H, Yue J, Zhou Q, Zhou T, Wang L, Liu X, Zhou X
Journal of controlled release : official journal of the Controlled Release Society 2023 Mar;355:54-67

Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.

Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65

Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis.

Yang X, Ou Y, Yang Y, Wang L, Zhang Y, Zhao F, Shui P, Qing J
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1242-1253

Ficolin A knockout alleviates sepsis-induced severe lung injury in mice by restoring gut Akkermansia to inhibit S100A4/STAT3 pathway.

Wu X, Xuan W, Yang X, Liu W, Zhang H, Jiang G, Cao B, Jiang Y
International immunopharmacology 2023 Aug;121:110548

Cancer-associated fibroblasts in the invasive tumour front promote the metastasis of oral squamous cell carcinoma through MFAP5 upregulation.

Wang Y, Wang R, Li B, Huang Z, Zhao S, Chen S, Lan T, Ren S, Wu F, Tan J, Li J
Gene 2023 Aug 5;876:147504

CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.

Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)

Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts.

Qian W, Xu Y, Wen W, Huang L, Guo Z, Zhu W, Li Y
Journal of Crohn's & colitis 2023 Aug 21;17(8):1291-1308

S100A4 Promotes BCG-Induced Pyroptosis of Macrophages by Activating the NF-κB/NLRP3 Inflammasome Signaling Pathway.

Li M, Liu Y, Nie X, Ma B, Ma Y, Hou Y, Yang Y, Xu J, Wang Y
International journal of molecular sciences 2023 Aug 11;24(16)

Stromal nicotinamide N-methyltransferase orchestrates the crosstalk between fibroblasts and tumour cells in oral squamous cell carcinoma: evidence from patient-derived assembled organoids.

Zhao H, Li R, Chen Y, Yang X, Shang Z
Oncogene 2023 Apr;42(15):1166-1180

Phenotype transition of fibroblasts incorporated into patient-derived oral carcinoma organoids.

Chen X, Li R, Zhao H, Wang X, Shao Z, Shang Z
Oral diseases 2023 Apr;29(3):913-922

An Integrated Proteomics and Metabolomics Strategy for the Mechanism of Calcium Oxalate Crystal-Induced Kidney Injury.

Gao S, Chao Y, Li N, Li H, Zhao H, Liu X, Chen W, Dong X
Frontiers in medicine 2022;9:805356

Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.

Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Journal of oncology 2022;2022:7630698

Halofuginone inhibits tumor migration and invasion by affecting cancer-associated fibroblasts in oral squamous cell carcinoma.

Wang D, Tian M, Fu Y, Sun Y, Ding L, Zhang X, Jing Y, Sun G, Ni Y, Song Y
Frontiers in pharmacology 2022;13:1056337

Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.

Parisi L, Rihs S, La Scala GC, Schnyder I, Katsaros C, Degen M
Stem cell research & therapy 2022 Sep 8;13(1):469

Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.

Yao F, Luo Y, Liu YC, Chen YH, Li YT, Hu XY, You XY, Yu SS, Li ZY, Chen L, Tian DS, Zheng MG, Cheng L, Jing JH
Inflammation and regeneration 2022 Sep 26;42(1):44

Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.

Wang L, Zhang Y, Ren Y, Yang X, Ben H, Zhao F, Yang S, Wang L, Qing J
European journal of pharmacology 2022 Oct 15;932:175241

Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.

Tong Y, Sun M, Chen L, Wang Y, Li Y, Li L, Zhang X, Cai Y, Qie J, Pang Y, Xu Z, Zhao J, Zhang X, Liu Y, Tian S, Qin Z, Feng J, Zhang F, Zhu J, Xu Y, Lou W, Ji Y, Zhao J, He F, Hou Y, Ding C
Journal of hematology & oncology 2022 Nov 25;15(1):168

A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates.

He P, Lim K, Sun D, Pett JP, Jeng Q, Polanski K, Dong Z, Bolt L, Richardson L, Mamanova L, Dabrowska M, Wilbrey-Clark A, Madissoon E, Tuong ZK, Dann E, Suo C, Goh I, Yoshida M, Nikolić MZ, Janes SM, He X, Barker RA, Teichmann SA, Marioni JC, Meyer KB, Rawlins EL
Cell 2022 Dec 8;185(25):4841-4860.e25

Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.

Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320

LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.

Zhou M, Wang S, Liu D, Zhou J
ACS biomaterials science & engineering 2021 Nov 8;7(11):5255-5268

Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.

Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188

Nox4-dependent upregulation of S100A4 after peripheral nerve injury modulates neuropathic pain processing.

Wack G, Metzner K, Kuth MS, Wang E, Bresnick A, Brandes RP, Schröder K, Wittig I, Schmidtko A, Kallenborn-Gerhardt W
Free radical biology & medicine 2021 May 20;168:155-167

Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.

Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.

Pietilä EA, Gonzalez-Molina J, Moyano-Galceran L, Jamalzadeh S, Zhang K, Lehtinen L, Turunen SP, Martins TA, Gultekin O, Lamminen T, Kaipio K, Joneborg U, Hynninen J, Hietanen S, Grénman S, Lehtonen R, Hautaniemi S, Carpén O, Carlson JW, Lehti K
Nature communications 2021 Jun 23;12(1):3904

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.

Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74

S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway.

Ou S, Liao Y, Shi J, Tang J, Ye Y, Wu F, Wang W, Fei J, Xie F, Bai L
Molecular medicine reports 2021 Feb;23(2)

Smart Manganese Dioxide-Based Lanthanide Nanoprobes for Triple-Negative Breast Cancer Precise Gene Synergistic Chemodynamic Therapy.

Ming L, Song L, Xu J, Wang R, Shi J, Chen M, Zhang Y
ACS applied materials & interfaces 2021 Aug 4;13(30):35444-35455

Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.

Wang W, Long H, Huang W, Zhang T, Xie L, Chen C, Liu J, Xiong D, Hu W
Frontiers in pharmacology 2020;11:587663

Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis.

Zhao L, Gu C, Gan Y, Shao L, Chen H, Zhu H
Journal of controlled release : official journal of the Controlled Release Society 2020 Feb;318:1-15

LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.

Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327

Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.

Wang X, Wang M, Chen S, Wei B, Gao Y, Huang L, Liu C, Huang T, Yu M, Zhao SH, Li X
Ecotoxicology and environmental safety 2020 Dec 1;205:111050

Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.

Zhang R, Qi F, Shao S, Li G, Feng Y
Cancer cell international 2019;19:192

ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins.

Al-Ismaeel Q, Neal CP, Al-Mahmoodi H, Almutairi Z, Al-Shamarti I, Straatman K, Jaunbocus N, Irvine A, Issa E, Moreman C, Dennison AR, Emre Sayan A, McDearmid J, Greaves P, Tulchinsky E, Kriajevska M
British journal of cancer 2019 Jul;121(1):65-75

Kindlin-2 links mechano-environment to proline synthesis and tumor growth.

Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C
Nature communications 2019 Feb 19;10(1):845

The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.

Wu DM, Zhang T, Liu YB, Deng SH, Han R, Liu T, Li J, Xu Y
Cell death & disease 2019 Apr 25;10(5):349

FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells.

Luo Q, Wang CQ, Yang LY, Gao XM, Sun HT, Zhang Y, Zhang KL, Zhu Y, Zheng Y, Sheng YY, Lu L, Jia HL, Yu WQ, Liu J, Dong QZ, Qin LX
Cancer letters 2018 Mar 28;417:21-34

ORMDL3 may participate in the pathogenesis of bronchial epithelial‑mesenchymal transition in asthmatic mice with airway remodeling.

Cheng Q, Shang Y
Molecular medicine reports 2018 Jan;17(1):995-1005

Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.

Zhang X, Cai Y, Zhang W, Chen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751

Killing the muscular larvae of Trichinella spiralis and the anti-fibrotic effect of the combination of Wortmannilatone F and recombinant G31P in a murine model of trichinellosis.

Ren Y, Qin Y, Zhang X, Zheng L, Dai X, Wu H, Dong Y, Cui Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:934-940

Inversed Expression Patterns of S100A4 and E-Cadherin in Cervical Cancers: Implication in Epithelial-Mesenchymal Transition.

Liu M, Liu J, Yang B, Gao X, Gao LL, Kong QY, Zhang P, Li H
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2184-2191

Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin.

Shi Z, Zhang J, Chen S, Li Y, Lei X, Qiao H, Zhu Q, Hu B, Zhou Q, Jiao J
The Journal of biological chemistry 2016 Jun 24;291(26):13560-70

Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.

Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130

Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex.

Shen H, Xu W, Guo R, Rong B, Gu L, Wang Z, He C, Zheng L, Hu X, Hu Z, Shao ZM, Yang P, Wu F, Shi YG, Shi Y, Lan F
Cell 2016 Apr 7;165(2):331-42

Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry.

Yin L, Coelho SG, Ebsen D, Smuda C, Mahns A, Miller SA, Beer JZ, Kolbe L, Hearing VJ
Experimental dermatology 2014 Oct;23(10):731-5

Retinoic acid receptor γ (Rarg) and nuclear receptor subfamily 5, group A, member 2 (Nr5a2) promote conversion of fibroblasts to functional neurons.

Shi Z, Shen T, Liu Y, Huang Y, Jiao J
The Journal of biological chemistry 2014 Mar 7;289(10):6415-6428

The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.

Zhang Y, Zhao Y, Li H, Li Y, Cai X, Shen Y, Shi H, Li L, Liu Q, Zhang X, Ye L
The Journal of biological chemistry 2013 Jun 28;288(26):18961-74

The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells.

Liu S, Li L, Zhang Y, Zhang Y, Zhao Y, You X, Lin Z, Zhang X, Ye L
The Journal of biological chemistry 2012 Aug 31;287(36):30228-39

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 16105-1-AP(S100A4 antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human breast cancer using 16105-1-AP(S100A4 antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The S100A4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human S100A4. This antibody recognizes human,mouse,rat antigen. The S100A4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 16105-1-AP.pdf

: Show more