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Learn16105-1-AP
antibody from Proteintech Group
Targeting: S100A4
18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [27]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 16105-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16105-1-AP, RRID:AB_11042591
- Product name
- S100A4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S100A4 antibody (Cat. #16105-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.
Phenotype transition of fibroblasts incorporated into patient-derived oral carcinoma organoids.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway.
Smart Manganese Dioxide-Based Lanthanide Nanoprobes for Triple-Negative Breast Cancer Precise Gene Synergistic Chemodynamic Therapy.
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis.
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins.
Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells.
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Killing the muscular larvae of Trichinella spiralis and the anti-fibrotic effect of the combination of Wortmannilatone F and recombinant G31P in a murine model of trichinellosis.
Inversed Expression Patterns of S100A4 and E-Cadherin in Cervical Cancers: Implication in Epithelial-Mesenchymal Transition.
Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex.
Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry.
Retinoic acid receptor γ (Rarg) and nuclear receptor subfamily 5, group A, member 2 (Nr5a2) promote conversion of fibroblasts to functional neurons.
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.
The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells.
Zhou M, Wang S, Liu D, Zhou J
ACS biomaterials science & engineering 2021 Nov 8;7(11):5255-5268
ACS biomaterials science & engineering 2021 Nov 8;7(11):5255-5268
Phenotype transition of fibroblasts incorporated into patient-derived oral carcinoma organoids.
Chen X, Li R, Zhao H, Wang X, Shao Z, Shang Z
Oral diseases 2021 Nov 5;
Oral diseases 2021 Nov 5;
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
Deficiency of Mitochondrial Glycerol 3-Phosphate Dehydrogenase Exacerbates Podocyte Injury and the Progression of Diabetic Kidney Disease.
Qu H, Gong X, Liu X, Zhang R, Wang Y, Huang B, Zhang L, Zheng H, Zheng Y
Diabetes 2021 Jun;70(6):1372-1387
Diabetes 2021 Jun;70(6):1372-1387
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.
Pietilä EA, Gonzalez-Molina J, Moyano-Galceran L, Jamalzadeh S, Zhang K, Lehtinen L, Turunen SP, Martins TA, Gultekin O, Lamminen T, Kaipio K, Joneborg U, Hynninen J, Hietanen S, Grénman S, Lehtonen R, Hautaniemi S, Carpén O, Carlson JW, Lehti K
Nature communications 2021 Jun 23;12(1):3904
Nature communications 2021 Jun 23;12(1):3904
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
S100A16 suppresses the proliferation, migration and invasion of colorectal cancer cells in part via the JNK/p38 MAPK pathway.
Ou S, Liao Y, Shi J, Tang J, Ye Y, Wu F, Wang W, Fei J, Xie F, Bai L
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Smart Manganese Dioxide-Based Lanthanide Nanoprobes for Triple-Negative Breast Cancer Precise Gene Synergistic Chemodynamic Therapy.
Ming L, Song L, Xu J, Wang R, Shi J, Chen M, Zhang Y
ACS applied materials & interfaces 2021 Aug 4;13(30):35444-35455
ACS applied materials & interfaces 2021 Aug 4;13(30):35444-35455
Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
Wang W, Long H, Huang W, Zhang T, Xie L, Chen C, Liu J, Xiong D, Hu W
Frontiers in pharmacology 2020;11:587663
Frontiers in pharmacology 2020;11:587663
Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis.
Zhao L, Gu C, Gan Y, Shao L, Chen H, Zhu H
Journal of controlled release : official journal of the Controlled Release Society 2020 Feb;318:1-15
Journal of controlled release : official journal of the Controlled Release Society 2020 Feb;318:1-15
LncRNA Gm16410 regulates PM2.5-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.
Wang X, Wang M, Chen S, Wei B, Gao Y, Huang L, Liu C, Huang T, Yu M, Zhao SH, Li X
Ecotoxicology and environmental safety 2020 Dec 1;205:111050
Ecotoxicology and environmental safety 2020 Dec 1;205:111050
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
Zhang R, Qi F, Shao S, Li G, Feng Y
Cancer cell international 2019;19:192
Cancer cell international 2019;19:192
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins.
Al-Ismaeel Q, Neal CP, Al-Mahmoodi H, Almutairi Z, Al-Shamarti I, Straatman K, Jaunbocus N, Irvine A, Issa E, Moreman C, Dennison AR, Emre Sayan A, McDearmid J, Greaves P, Tulchinsky E, Kriajevska M
British journal of cancer 2019 Jul;121(1):65-75
British journal of cancer 2019 Jul;121(1):65-75
Kindlin-2 links mechano-environment to proline synthesis and tumor growth.
Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, Chen K, Yuan J, Xiao G, Tang B, Sun Y, Wu C
Nature communications 2019 Feb 19;10(1):845
Nature communications 2019 Feb 19;10(1):845
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Wu DM, Zhang T, Liu YB, Deng SH, Han R, Liu T, Li J, Xu Y
Cell death & disease 2019 Apr 25;10(5):349
Cell death & disease 2019 Apr 25;10(5):349
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells.
Luo Q, Wang CQ, Yang LY, Gao XM, Sun HT, Zhang Y, Zhang KL, Zhu Y, Zheng Y, Sheng YY, Lu L, Jia HL, Yu WQ, Liu J, Dong QZ, Qin LX
Cancer letters 2018 Mar 28;417:21-34
Cancer letters 2018 Mar 28;417:21-34
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.
Zhang X, Cai Y, Zhang W, Chen X
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Dec;96(6):742-751
Killing the muscular larvae of Trichinella spiralis and the anti-fibrotic effect of the combination of Wortmannilatone F and recombinant G31P in a murine model of trichinellosis.
Ren Y, Qin Y, Zhang X, Zheng L, Dai X, Wu H, Dong Y, Cui Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:934-940
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:934-940
Inversed Expression Patterns of S100A4 and E-Cadherin in Cervical Cancers: Implication in Epithelial-Mesenchymal Transition.
Liu M, Liu J, Yang B, Gao X, Gao LL, Kong QY, Zhang P, Li H
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2184-2191
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2184-2191
Conversion of Fibroblasts to Parvalbumin Neurons by One Transcription Factor, Ascl1, and the Chemical Compound Forskolin.
Shi Z, Zhang J, Chen S, Li Y, Lei X, Qiao H, Zhu Q, Hu B, Zhou Q, Jiao J
The Journal of biological chemistry 2016 Jun 24;291(26):13560-70
The Journal of biological chemistry 2016 Jun 24;291(26):13560-70
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Suppression of Enhancer Overactivation by a RACK7-Histone Demethylase Complex.
Shen H, Xu W, Guo R, Rong B, Gu L, Wang Z, He C, Zheng L, Hu X, Hu Z, Shao ZM, Yang P, Wu F, Shi YG, Shi Y, Lan F
Cell 2016 Apr 7;165(2):331-42
Cell 2016 Apr 7;165(2):331-42
Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry.
Yin L, Coelho SG, Ebsen D, Smuda C, Mahns A, Miller SA, Beer JZ, Kolbe L, Hearing VJ
Experimental dermatology 2014 Oct;23(10):731-5
Experimental dermatology 2014 Oct;23(10):731-5
Retinoic acid receptor γ (Rarg) and nuclear receptor subfamily 5, group A, member 2 (Nr5a2) promote conversion of fibroblasts to functional neurons.
Shi Z, Shen T, Liu Y, Huang Y, Jiao J
The Journal of biological chemistry 2014 Mar 7;289(10):6415-6428
The Journal of biological chemistry 2014 Mar 7;289(10):6415-6428
The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells.
Zhang Y, Zhao Y, Li H, Li Y, Cai X, Shen Y, Shi H, Li L, Liu Q, Zhang X, Ye L
The Journal of biological chemistry 2013 Jun 28;288(26):18961-74
The Journal of biological chemistry 2013 Jun 28;288(26):18961-74
The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells.
Liu S, Li L, Zhang Y, Zhang Y, Zhao Y, You X, Lin Z, Zhang X, Ye L
The Journal of biological chemistry 2012 Aug 31;287(36):30228-39
The Journal of biological chemistry 2012 Aug 31;287(36):30228-39
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 16105-1-AP(S100A4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 16105-1-AP(S100A4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The S100A4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human S100A4. This antibody recognizes human,mouse,rat antigen. The S100A4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
