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- Antigen structure
- References [11]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17067-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17067-1-AP, RRID:AB_2132693
- Product name
- LARP7 antibody
- Antibody type
- Polyclonal
- Description
- LARP7 antibody (Cat. #17067-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references N(6)-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation.
Interaction of 7SK with the Smn complex modulates snRNP production.
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation.
Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex.
Human METTL16 is a N(6)-methyladenosine (m(6)A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.
HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters.
Loss of function mutation in LARP7, chaperone of 7SK ncRNA, causes a syndrome of facial dysmorphism, intellectual disability, and primordial dwarfism.
Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells.
7SK snRNA-mediated, gene-specific cooperativity of HMGA1 and P-TEFb.
7SK small nuclear RNA directly affects HMGA1 function in transcription regulation.
Wang Y, Traugot CM, Bubenik JL, Li T, Sheng P, Hiers NM, Fernandez P, Li L, Bian J, Swanson MS, Xie M
Molecular cell 2023 Nov 2;83(21):3818-3834.e7
Molecular cell 2023 Nov 2;83(21):3818-3834.e7
Interaction of 7SK with the Smn complex modulates snRNP production.
Ji C, Bader J, Ramanathan P, Hennlein L, Meissner F, Jablonka S, Mann M, Fischer U, Sendtner M, Briese M
Nature communications 2021 Feb 24;12(1):1278
Nature communications 2021 Feb 24;12(1):1278
Aberrant miR-1246 expression promotes radioresistance in non-small cell lung cancer: a potential prognostic biomarker and radiotherapy sensitization target.
Fan L, Wang J, Cao Q, Ding X, Li B
American journal of cancer research 2020;10(1):314-335
American journal of cancer research 2020;10(1):314-335
de novo MEPCE nonsense variant associated with a neurodevelopmental disorder causes disintegration of 7SK snRNP and enhanced RNA polymerase II activation.
Schneeberger PE, Bierhals T, Neu A, Hempel M, Kutsche K
Scientific reports 2019 Aug 29;9(1):12516
Scientific reports 2019 Aug 29;9(1):12516
Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex.
Von Dwingelo J, Chung IYW, Price CT, Li L, Jones S, Cygler M, Abu Kwaik Y
mBio 2019 Aug 27;10(4)
mBio 2019 Aug 27;10(4)
Human METTL16 is a N(6)-methyladenosine (m(6)A) methyltransferase that targets pre-mRNAs and various non-coding RNAs.
Warda AS, Kretschmer J, Hackert P, Lenz C, Urlaub H, Höbartner C, Sloan KE, Bohnsack MT
EMBO reports 2017 Nov;18(11):2004-2014
EMBO reports 2017 Nov;18(11):2004-2014
HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters.
Eilebrecht S, Le Douce V, Riclet R, Targat B, Hallay H, Van Driessche B, Schwartz C, Robette G, Van Lint C, Rohr O, Benecke AG
Nucleic acids research 2014 Apr;42(8):4962-71
Nucleic acids research 2014 Apr;42(8):4962-71
Loss of function mutation in LARP7, chaperone of 7SK ncRNA, causes a syndrome of facial dysmorphism, intellectual disability, and primordial dwarfism.
Alazami AM, Al-Owain M, Alzahrani F, Shuaib T, Al-Shamrani H, Al-Falki YH, Al-Qahtani SM, Alsheddi T, Colak D, Alkuraya FS
Human mutation 2012 Oct;33(10):1429-34
Human mutation 2012 Oct;33(10):1429-34
Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells.
Okamura D, Maeda I, Taniguchi H, Tokitake Y, Ikeda M, Ozato K, Mise N, Abe K, Noce T, Izpisua Belmonte JC, Matsui Y
Genes & development 2012 Nov 15;26(22):2477-82
Genes & development 2012 Nov 15;26(22):2477-82
7SK snRNA-mediated, gene-specific cooperativity of HMGA1 and P-TEFb.
Eilebrecht S, Benecke BJ, Benecke A
RNA biology 2011 Nov-Dec;8(6):1084-93
RNA biology 2011 Nov-Dec;8(6):1084-93
7SK small nuclear RNA directly affects HMGA1 function in transcription regulation.
Eilebrecht S, Brysbaert G, Wegert T, Urlaub H, Benecke BJ, Benecke A
Nucleic acids research 2011 Mar;39(6):2057-72
Nucleic acids research 2011 Mar;39(6):2057-72
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 17067-1-AP(LARP7 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 17067-1-AP(LARP7 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LARP7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LARP7. This antibody recognizes human, mouse, rat antigen. The LARP7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
