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- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15378-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15378-1-AP, RRID:AB_2077501
- Product name
- CES2 antibody
- Antibody type
- Polyclonal
- Description
- CES2 antibody (Cat. #15378-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Differential expression of capecitabine-related metabolic enzymes in hepatocellular carcinoma and its clinical value: a retrospective cohort study.
KLF13-mediated CES2 upregulation via p300-dependent acetylation sensitizes gastric cancer cells to irinotecan.
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
Lu J, Yin Z, Zhuang Y, Wang Z, Zheng H, Cao L, Kong D, Duan J, Chen S, Chen T
Discover oncology 2025 Jun 12;16(1):1066
Discover oncology 2025 Jun 12;16(1):1066
KLF13-mediated CES2 upregulation via p300-dependent acetylation sensitizes gastric cancer cells to irinotecan.
Zhang HB, Hu RH, Zhang KH, Cui XM, Zhang S
iScience 2025 Dec 19;28(12):114199
iScience 2025 Dec 19;28(12):114199
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Chen X, Liu Q, Chen Y, Wang L, Yang R, Zhang W, Pan X, Zhang S, Chen C, Wu T, Xia J, Cheng B, Chen X, Ren X
Molecular metabolism 2022 Nov;65:101600
Molecular metabolism 2022 Nov;65:101600
Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.
Luo W, Xin Y, Zhao X, Zhang F, Liu C, Fan H, Xi T, Xiong J
British journal of pharmacology 2017 Apr;174(8):700-717
British journal of pharmacology 2017 Apr;174(8):700-717
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
Sato Y, Miyashita A, Iwatsubo T, Usui T
Drug metabolism and disposition: the biological fate of chemicals 2012 Jul;40(7):1389-96
Drug metabolism and disposition: the biological fate of chemicals 2012 Jul;40(7):1389-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human stomach tissue were subjected to SDS PAGE followed by western blot with 15378-1-AP(CES2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15378-1-AP(CES2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CES2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CES2. This antibody recognizes human antigen. The CES2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
