Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- H00008824-M02 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00008824-M02, RRID:AB_828725
- Product name
- Mouse Monoclonal Carboxylesterase 2/CES2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. CES2 (4F12)
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Clinical implications of CES2 RNA expression in neuroblastoma.
Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells.
Uchida K, Otake K, Tanaka K, Hashimoto K, Saigusa S, Matsushita K, Koike Y, Inoue M, Ueeda M, Okugawa Y, Inoue Y, Mohri Y, Kusunoki M
Journal of pediatric surgery 2013 Mar;48(3):502-9
Journal of pediatric surgery 2013 Mar;48(3):502-9
Human carboxylesterase-2 hydrolyzes the prodrug of gemcitabine (LY2334737) and confers prodrug sensitivity to cancer cells.
Pratt SE, Durland-Busbice S, Shepard RL, Heinz-Taheny K, Iversen PW, Dantzig AH
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 1;19(5):1159-68
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 1;19(5):1159-68
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CES2 Antibody (4F12) [H00008824-M02] - CES2 monoclonal antibody (M02), clone 4F12 Analysis of CES2 expression in HepG2.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: CES2 Antibody (4F12) [H00008824-M02] - Detection limit for recombinant GST tagged CES2 is approximately 0.3ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CES2 Antibody (4F12) [H00008824-M02] - Analysis of monoclonal antibody to CES2 on formalin-fixed paraffin-embedded human colon. Antibody concentration 3 ug/ml.
