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- References [12]
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- Product number
- 13669-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13669-1-AP, RRID:AB_2162104
- Product name
- PEX1 antibody
- Antibody type
- Polyclonal
- Description
- PEX1 antibody (Cat. #13669-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TFEB activation triggers pexophagy for functional adaptation during oxidative stress under calcium deficient-conditions.
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss.
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
A longitudinal study of retinopathy in the PEX1-Gly844Asp mouse model for mild Zellweger Spectrum Disorder.
Zellweger spectrum disorder patient-derived fibroblasts with the PEX1-Gly843Asp allele recover peroxisome functions in response to flavonoids.
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence.
Spectrum of PEX1 and PEX6 variants in Heimler syndrome.
Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts.
Manandhar L, Dutta RK, Devkota P, Chhetri A, Wei X, Park C, Kwon HM, Park R
Cell communication and signaling : CCS 2024 Feb 21;22(1):142
Cell communication and signaling : CCS 2024 Feb 21;22(1):142
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis.
Ott J, Sehr J, Schmidt N, Schliebs W, Erdmann R
Biological chemistry 2023 Feb 23;404(2-3):209-219
Biological chemistry 2023 Feb 23;404(2-3):209-219
Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss.
Mauriac SA, Peineau T, Zuberi A, Lutz C, Géléoc GSG
Cells 2022 Dec 9;11(24)
Cells 2022 Dec 9;11(24)
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell.
Mu Y, Maharjan Y, Kumar Dutta R, Wei X, Kim JH, Son J, Park C, Park R
PloS one 2021;16(2):e0245799
PloS one 2021;16(2):e0245799
AAV-mediated PEX1 gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder.
Argyriou C, Polosa A, Song JY, Omri S, Steele B, Cécyre B, McDougald DS, Di Pietro E, Bouchard JF, Bennett J, Hacia JG, Lachapelle P, Braverman NE
Molecular therapy. Methods & clinical development 2021 Dec 10;23:225-240
Molecular therapy. Methods & clinical development 2021 Dec 10;23:225-240
Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.
Miyamoto T, Hosoba K, Itabashi T, Iwane AH, Akutsu SN, Ochiai H, Saito Y, Yamamoto T, Matsuura S
The EMBO journal 2020 Jun 17;39(12):e103499
The EMBO journal 2020 Jun 17;39(12):e103499
A longitudinal study of retinopathy in the PEX1-Gly844Asp mouse model for mild Zellweger Spectrum Disorder.
Argyriou C, Polosa A, Cecyre B, Hsieh M, Di Pietro E, Cui W, Bouchard JF, Lachapelle P, Braverman N
Experimental eye research 2019 Sep;186:107713
Experimental eye research 2019 Sep;186:107713
Zellweger spectrum disorder patient-derived fibroblasts with the PEX1-Gly843Asp allele recover peroxisome functions in response to flavonoids.
MacLean GE, Argyriou C, Di Pietro E, Sun X, Birjandian S, Saberian P, Hacia JG, Braverman NE
Journal of cellular biochemistry 2019 Mar;120(3):3243-3258
Journal of cellular biochemistry 2019 Mar;120(3):3243-3258
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.
Ni Z, He J, Wu Y, Hu C, Dai X, Yan X, Li B, Li X, Xiong H, Li Y, Li S, Xu L, Li Y, Lian J, He F
Autophagy 2018;14(4):685-701
Autophagy 2018;14(4):685-701
A signature of enhanced lipid metabolism, lipid peroxidation and aldehyde stress in therapy-induced senescence.
Flor AC, Wolfgeher D, Wu D, Kron SJ
Cell death discovery 2017;3:17075
Cell death discovery 2017;3:17075
Spectrum of PEX1 and PEX6 variants in Heimler syndrome.
Smith CE, Poulter JA, Levin AV, Capasso JE, Price S, Ben-Yosef T, Sharony R, Newman WG, Shore RC, Brookes SJ, Mighell AJ, Inglehearn CF
European journal of human genetics : EJHG 2016 Nov;24(11):1565-1571
European journal of human genetics : EJHG 2016 Nov;24(11):1565-1571
Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts.
Nordgren M, Francisco T, Lismont C, Hennebel L, Brees C, Wang B, Van Veldhoven PP, Azevedo JE, Fransen M
Autophagy 2015;11(8):1326-40
Autophagy 2015;11(8):1326-40
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PEX1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PEX1. This antibody recognizes human, mouse, rat antigen. The PEX1 antibody has been validated for the following applications: ELISA, WB analysis.
