Antibody data
- Antibody Data
- Antigen structure
- References [38]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 13687-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13687-1-AP, RRID:AB_10644337
- Product name
- VEGFR-1/FLT-1 antibody
- Antibody type
- Polyclonal
- Description
- VEGFR-1/FLT-1 antibody (Cat. #13687-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prenatal triphenyl phosphate exposure impairs placentation and induces preeclampsia-like symptoms in mice.
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway.
Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages.
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Effects of total coumarins from Pileostegia tomentella on exosomal miRNA expression and angiogenesis in colorectal cancer cells.
Statins Prevent the Deleterious Consequences of Placental Chemerin Upregulation in Preeclampsia.
Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.
Effects of early exercise on cardiac function and lipid metabolism pathway in heart failure.
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Optimizing human endometrial mesenchymal stem cells for maximal induction of angiogenesis.
BEST1 Positive Monocytes in Circulation: Visualize Intratumoral Crosstalk between Cancer Cells and Monocytes.
Delivery of miR-130a-3p Through Adipose-Derived Stem Cell-Secreted EVs Protects Against Diabetic Peripheral Neuropathy via DNMT1/NRF2/HIF1α/ACTA1 Axis.
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Catalpol Prevents Glomerular Angiogenesis Induced by Advanced Glycation End Products via Inhibiting Galectin-3.
Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.
Impact of repeated intravenous infusions of umbilical cord-derived versus bone marrow-derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model.
Honeymoon Period in Newborn Rats With CDH Is Associated With Changes in the VEGF Signaling Pathway.
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats.
Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Biocompatible Chitin Hydrogel Incorporated with PEDOT Nanoparticles for Peripheral Nerve Repair.
Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure.
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway.
PlGF signaling and macrophage repolarization contribute to the anti-neoplastic effect of metformin.
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R.
Screening of differentially expressed proteins from syncytiotrophoblast for severe early-onset preeclampsia in women with gestational diabetes mellitus using tandem mass tag quantitative proteomics.
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes.
Vascular endothelial growth factor is neuroprotective against ischemic brain injury by inhibiting scavenger receptor A expression on microglia.
The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice.
The Effects of Taoren-Honghua Herb Pair on Pathological Microvessel and Angiogenesis-Associated Signaling Pathway in Mice Model of CCl4-Induced Chronic Liver Disease.
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in a murine model of chronic liver disease.
Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis.
Liu Q, Jiang M, Lu X, Hong J, Sun Y, Yang C, Chen Y, Chai X, Tang H, Liu X
Environmental research 2024 Sep 15;257:119159
Environmental research 2024 Sep 15;257:119159
Sorcin promotes proliferation of hepatocellular carcinoma by regulating VEGFA/B via PI3K pathway.
Zhang H, Hu S, Sanches JGP, Li Y, Wei Y, Pu C, Zhang J
Journal of physiology and biochemistry 2024 May;80(2):381-392
Journal of physiology and biochemistry 2024 May;80(2):381-392
Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages.
Tanaka H, Ozawa R, Henmi Y, Hosoda M, Karasawa T, Takahashi M, Takahashi H, Iwata H, Kuwayama T, Shirasuna K
Reproductive biology 2024 Mar;24(1):100857
Reproductive biology 2024 Mar;24(1):100857
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway.
Sun J, Zhang W
Heliyon 2024 Jan 30;10(2):e24575
Heliyon 2024 Jan 30;10(2):e24575
Effects of total coumarins from Pileostegia tomentella on exosomal miRNA expression and angiogenesis in colorectal cancer cells.
Liu Y, Cheng DH, Su ZY, Lv JH, Wang L, Deng YY, Li L
Pharmaceutical biology 2024 Dec;62(1):153-161
Pharmaceutical biology 2024 Dec;62(1):153-161
Statins Prevent the Deleterious Consequences of Placental Chemerin Upregulation in Preeclampsia.
Tan L, Kluivers ACM, Cruz-López EO, Broekhuizen M, Chen Z, Neuman RI, Schoenmakers S, Ruijgrok L, van de Velde D, de Winter BCM, van den Bogaerdt AJ, Lu X, Danser AHJ, Verdonk K
Hypertension (Dallas, Tex. : 1979) 2024 Apr;81(4):861-875
Hypertension (Dallas, Tex. : 1979) 2024 Apr;81(4):861-875
Diterpenoid tanshinones inhibit gastric cancer angiogenesis through the PI3K/Akt/mTOR signaling pathway.
Yu JR, Liu YY, Gao YY, Qian LH, Qiu JL, Wang PP, Zhang GJ
Journal of ethnopharmacology 2024 Apr 24;324:117791
Journal of ethnopharmacology 2024 Apr 24;324:117791
Effects of early exercise on cardiac function and lipid metabolism pathway in heart failure.
de Souza SLB, Mota GAF, da Silva VL, Vileigas DF, Sant'Ana PG, Gregolin CS, Figueira RL, Batah SS, Fabro AT, Murata GM, Bazan SGZ, Okoshi MP, Cicogna AC
Journal of cellular and molecular medicine 2023 Oct;27(19):2956-2969
Journal of cellular and molecular medicine 2023 Oct;27(19):2956-2969
Lychee seed polyphenol ameliorates DR via inhibiting inflammasome/apoptosis and angiogenesis in hRECs and db/db mice.
Xiang XH, Wei J, Wang XF, Xu Q, Yu CL, He CL, Long T, Guo MS, Chen X, Zhou XG, Wu JM, Qin DL, Wu AG, Tang Y, Lv HB
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115478
P53 Deficiency Accelerate Esophageal Epithelium Intestinal Metaplasia Malignancy.
Qiu Q, Guo G, Guo X, Hu X, Yu T, Liu G, Zhang H, Chen Y, She J
Biomedicines 2023 Mar 13;11(3)
Biomedicines 2023 Mar 13;11(3)
Optimizing human endometrial mesenchymal stem cells for maximal induction of angiogenesis.
Zhang J, Song H, Fan X, He S, Yin W, Peng Z, Zhai X, Yang K, Gong H, Wang Z, Ping Y, Zhang S, Li RK, Xie J
Molecular and cellular biochemistry 2023 Jun;478(6):1191-1204
Molecular and cellular biochemistry 2023 Jun;478(6):1191-1204
BEST1 Positive Monocytes in Circulation: Visualize Intratumoral Crosstalk between Cancer Cells and Monocytes.
Zhang L, Wang Y, Yuan W, An C, Tan Q, Ma J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2205915
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2205915
Delivery of miR-130a-3p Through Adipose-Derived Stem Cell-Secreted EVs Protects Against Diabetic Peripheral Neuropathy via DNMT1/NRF2/HIF1α/ACTA1 Axis.
Chen J, Li G, Liu X, Chen K, Wang Y, Qin J, Yang F
Molecular neurobiology 2023 Jul;60(7):3678-3694
Molecular neurobiology 2023 Jul;60(7):3678-3694
NRP1 contributes to stemness and potentiates radioresistance via WTAP-mediated m6A methylation of Bcl-2 mRNA in breast cancer.
Wang Y, Zhang L, Sun XL, Lu YC, Chen S, Pei DS, Zhang LS
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
Apoptosis : an international journal on programmed cell death 2023 Feb;28(1-2):233-246
Catalpol Prevents Glomerular Angiogenesis Induced by Advanced Glycation End Products via Inhibiting Galectin-3.
Sun WX, Gao YY, Cao Y, Lu JF, Lv GH, Xu HQ
Current medical science 2023 Aug;43(4):668-678
Current medical science 2023 Aug;43(4):668-678
Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland.
Zhang J, Yan X, Liu R, Wu S, Liu Q, Li J, Ma J
Cancer management and research 2022;14:1023-1032
Cancer management and research 2022;14:1023-1032
Impact of repeated intravenous infusions of umbilical cord-derived versus bone marrow-derived mesenchymal stem cells on angiogenesis in a pregnant experimentally induced deep venous thrombosis rat model.
Cheng X, Wang W, Du R, Zhang M, Xie Y, Sun W, Ji J, Sun B, Zhang Y
In vitro cellular & developmental biology. Animal 2022 Dec;58(10):957-969
In vitro cellular & developmental biology. Animal 2022 Dec;58(10):957-969
Honeymoon Period in Newborn Rats With CDH Is Associated With Changes in the VEGF Signaling Pathway.
Miura da Costa K, Fabro AT, Becari C, Figueira RL, Schmidt AF, Ruano R, Sbragia L
Frontiers in pediatrics 2021;9:698217
Frontiers in pediatrics 2021;9:698217
IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways.
Nisar MA, Zheng Q, Saleem MZ, Ahmmed B, Ramzan MN, Ud Din SR, Tahir N, Liu S, Yan Q
Frontiers in oncology 2021;11:618839
Frontiers in oncology 2021;11:618839
Effects of S1PR2 antagonist on blood pressure and angiogenesis imbalance in preeclampsia rats.
Zhang T, Guo D, Zheng W, Dai Q
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism.
Fan X, He S, Song H, Yin W, Zhang J, Peng Z, Yang K, Zhai X, Zhao L, Gong H, Ping Y, Jiao X, Zhang S, Yan C, Wang H, Li RK, Xie J
Stem cell research & therapy 2021 Jun 10;12(1):344
Stem cell research & therapy 2021 Jun 10;12(1):344
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Biocompatible Chitin Hydrogel Incorporated with PEDOT Nanoparticles for Peripheral Nerve Repair.
Huang L, Yang X, Deng L, Ying D, Lu A, Zhang L, Yu A, Duan B
ACS applied materials & interfaces 2021 Apr 14;13(14):16106-16117
ACS applied materials & interfaces 2021 Apr 14;13(14):16106-16117
Genome-wide translational reprogramming of genes important for myocyte functions in overload-induced heart failure.
Guo Q, Zhang Y, Zhang S, Jin J, Pang S, Wu X, Zhang W, Bi X, Zhang Y, Zhang Q, Jiang F
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165649
Biochimica et biophysica acta. Molecular basis of disease 2020 Mar 1;1866(3):165649
Decreased ZNF750 promotes angiogenesis in a paracrine manner via activating DANCR/miR-4707-3p/FOXC2 axis in esophageal squamous cell carcinoma.
Bi Y, Guo S, Xu X, Kong P, Cui H, Yan T, Ma Y, Cheng Y, Chen Y, Liu X, Zhang L, Cheng C, Xu E, Qian Y, Yang J, Song B, Li H, Wang F, Hu X, Liu X, Niu X, Zhai Y, Liu J, Li Y, Cheng X, Cui Y
Cell death & disease 2020 Apr 27;11(4):296
Cell death & disease 2020 Apr 27;11(4):296
RhTyrRS (Y341A), a novel human tyrosyl-tRNA synthetase mutant, stimulates thrombopoiesis through activation of the VEGF-R II/NF-κB pathway.
Shi Y, Yu J, Zhang Y, Zhao B, Li Y, Ye Y, Yu Q, Yu M, Mo W, Gu J
Biochemical pharmacology 2019 Nov;169:113634
Biochemical pharmacology 2019 Nov;169:113634
PlGF signaling and macrophage repolarization contribute to the anti-neoplastic effect of metformin.
Ma Q, Gu JT, Wang B, Feng J, Yang L, Kang XW, Duan P, Sun X, Liu PJ, Wang JC
European journal of pharmacology 2019 Nov 15;863:172696
European journal of pharmacology 2019 Nov 15;863:172696
Exosomal miR-1229 derived from colorectal cancer cells promotes angiogenesis by targeting HIPK2.
Hu HY, Yu CH, Zhang HH, Zhang SZ, Yu WY, Yang Y, Chen Q
International journal of biological macromolecules 2019 Jul 1;132:470-477
International journal of biological macromolecules 2019 Jul 1;132:470-477
Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R.
Han Y, Ren J, Bai Y, Pei X, Han Y
The international journal of biochemistry & cell biology 2019 Apr;109:59-68
The international journal of biochemistry & cell biology 2019 Apr;109:59-68
Screening of differentially expressed proteins from syncytiotrophoblast for severe early-onset preeclampsia in women with gestational diabetes mellitus using tandem mass tag quantitative proteomics.
Sun X, Qu T, He X, Yang X, Guo N, Mao Y, Xu X, Sun X, Zhang X, Wang W
BMC pregnancy and childbirth 2018 Nov 7;18(1):437
BMC pregnancy and childbirth 2018 Nov 7;18(1):437
Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration.
Zhang W, Chu W, Liu Q, Coates D, Shang Y, Li C
Stem cell research & therapy 2018 Jun 19;9(1):166
Stem cell research & therapy 2018 Jun 19;9(1):166
Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes.
Tanaka K, Watanabe M, Tanigaki S, Iwashita M, Kobayashi Y
Placenta 2018 Dec 15;74:20-27
Placenta 2018 Dec 15;74:20-27
Vascular endothelial growth factor is neuroprotective against ischemic brain injury by inhibiting scavenger receptor A expression on microglia.
Xu Z, Han K, Chen J, Wang C, Dong Y, Yu M, Bai R, Huang C, Hou L
Journal of neurochemistry 2017 Sep;142(5):700-709
Journal of neurochemistry 2017 Sep;142(5):700-709
The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice.
Denslow A, Switalska M, Nowak M, Maciejewska M, Chlopicki S, Marcinek A, Gebicki J, Wietrzyk J
BMC cancer 2017 Mar 7;17(1):177
BMC cancer 2017 Mar 7;17(1):177
The Effects of Taoren-Honghua Herb Pair on Pathological Microvessel and Angiogenesis-Associated Signaling Pathway in Mice Model of CCl4-Induced Chronic Liver Disease.
Xi S, Yue L, Shi M, Peng Y, Xu Y, Wang X, Li Q, Kang Z, Li H, Wang Y
Evidence-based complementary and alternative medicine : eCAM 2016;2016:2974256
Evidence-based complementary and alternative medicine : eCAM 2016;2016:2974256
Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis.
Shi L, Yang F, Luo F, Liu Y, Zhang F, Zou M, Liu Q
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):12791-12803
The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in a murine model of chronic liver disease.
Xi S, Shi M, Jiang X, Minuk GY, Cheng Y, Peng Y, Gong Y, Xu Y, Wang X, Yang J, Yue L, Wang Y
Journal of ethnopharmacology 2016 Mar 2;180:28-36
Journal of ethnopharmacology 2016 Mar 2;180:28-36
Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis.
Hu X, Zhang L, Jin J, Zhu W, Xu Y, Wu Y, Wang Y, Chen H, Webster KA, Chen H, Yu H, Wang J
Stem cells (Dayton, Ohio) 2015 Jun;33(6):1850-1862
Stem cells (Dayton, Ohio) 2015 Jun;33(6):1850-1862
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 13687-1-AP(VEGFR1, FLT1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VEGFR-1/FLT-1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VEGFR-1/FLT-1. This antibody recognizes human,mouse,rat antigen. The VEGFR-1/FLT-1 antibody has been validated for the following applications: ELISA, WB, IP analysis.