Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 22097-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ISG20 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ISG20 antibody (Cat. #22097-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TGF β1 promotes the polarization of M2-type macrophages and activates PI3K/mTOR signaling pathway by inhibiting ISG20 to sensitize ovarian cancer to cisplatin.
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response.
Identification of disulfidptosis-related subtypes and development of a prognosis model based on stacking framework in renal clear cell carcinoma.
Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus.
Integrated bioinformatics analysis and experimental validation reveal ISG20 as a novel prognostic indicator expressed on M2 macrophage in glioma.
Proteomics Profiling Reveals Regulation of Immune Response to Salmonella enterica Serovar Typhimurium Infection in Mice.
Internal RNA 2'O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect.
RSAD2 Is an Effective Target for High-Yield Vaccine Production in MDCK Cells.
Identification of key biomarkers and immune infiltration in renal interstitial fibrosis.
Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection.
Identification and validation of a novel glycolysis-related gene signature for predicting the prognosis in ovarian cancer.
Development and validation of an interferon signature predicting prognosis and treatment response for glioblastoma.
The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation.
Lnc-ISG20 Inhibits Influenza A Virus Replication by Enhancing ISG20 Expression.
Wu J, Jiang L, Wang S, Peng L, Zhang R, Liu Z
International immunopharmacology 2024 Jun 15;134:112235
International immunopharmacology 2024 Jun 15;134:112235
Interferon inhibits a model RNA virus via a limited set of inducible effector genes.
McDougal MB, De Maria AM, Ohlson MB, Kumar A, Xing C, Schoggins JW
EMBO reports 2023 Sep 6;24(9):e56901
EMBO reports 2023 Sep 6;24(9):e56901
Enzymolysis-based RNA pull-down identifies YTHDC2 as an inhibitor of antiviral innate response.
Zhu J, Liu S, Fang J, Cui Z, Wang B, Wang Y, Liu L, Wang Q, Cao X
Cell reports 2023 Oct 31;42(10):113192
Cell reports 2023 Oct 31;42(10):113192
Identification of disulfidptosis-related subtypes and development of a prognosis model based on stacking framework in renal clear cell carcinoma.
Peng K, Wang N, Liu Q, Wang L, Duan X, Xie G, Li J, Ding D
Journal of cancer research and clinical oncology 2023 Nov;149(15):13793-13810
Journal of cancer research and clinical oncology 2023 Nov;149(15):13793-13810
Characterization of the induction kinetics and antiviral functions of IRF1, ISG15 and ISG20 in cells infected with gammacoronavirus avian infectious bronchitis virus.
Liu SY, Huang M, Fung TS, Chen RA, Liu DX
Virology 2023 May;582:114-127
Virology 2023 May;582:114-127
Integrated bioinformatics analysis and experimental validation reveal ISG20 as a novel prognostic indicator expressed on M2 macrophage in glioma.
Peng Y, Liu H, Wu Q, Wang L, Yu Y, Yin F, Feng C, Ren X, Liu T, Chen L, Zhu H
BMC cancer 2023 Jun 28;23(1):596
BMC cancer 2023 Jun 28;23(1):596
Proteomics Profiling Reveals Regulation of Immune Response to Salmonella enterica Serovar Typhimurium Infection in Mice.
Huang H, Even Z, Wang Z, Li L, Erickson A, Golovko M, Golovko S, Darland D, Mathur R, Wang X
Infection and immunity 2023 Jan 24;91(1):e0049922
Infection and immunity 2023 Jan 24;91(1):e0049922
Internal RNA 2'O-methylation in the HIV-1 genome counteracts ISG20 nuclease-mediated antiviral effect.
El Kazzi P, Rabah N, Chamontin C, Poulain L, Ferron F, Debart F, Canard B, Missé D, Coutard B, Nisole S, Decroly E
Nucleic acids research 2023 Apr 11;51(6):2501-2515
Nucleic acids research 2023 Apr 11;51(6):2501-2515
RSAD2 Is an Effective Target for High-Yield Vaccine Production in MDCK Cells.
Qiao Z, Liao Y, Pei M, Qiu Z, Liu Z, Jin D, Zhang J, Ma Z, Yang X
Viruses 2022 Nov 21;14(11)
Viruses 2022 Nov 21;14(11)
Identification of key biomarkers and immune infiltration in renal interstitial fibrosis.
Hu Z, Liu Y, Zhu Y, Cui H, Pan J
Annals of translational medicine 2022 Feb;10(4):190
Annals of translational medicine 2022 Feb;10(4):190
Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection.
Ding J, Aldo P, Roberts CM, Stabach P, Liu H, You Y, Qiu X, Jeong J, Maxwell A, Lindenbach B, Braddock D, Liao A, Mor G
EMBO reports 2021 Oct 5;22(10):e52450
EMBO reports 2021 Oct 5;22(10):e52450
Identification and validation of a novel glycolysis-related gene signature for predicting the prognosis in ovarian cancer.
Yu J, Liu TT, Liang LL, Liu J, Cai HQ, Zeng J, Wang TT, Li J, Xiu L, Li N, Wu LY
Cancer cell international 2021 Jul 6;21(1):353
Cancer cell international 2021 Jul 6;21(1):353
Development and validation of an interferon signature predicting prognosis and treatment response for glioblastoma.
Zhu C, Zou C, Guan G, Guo Q, Yan Z, Liu T, Shen S, Xu X, Chen C, Lin Z, Cheng W, Wu A
Oncoimmunology 2019;8(9):e1621677
Oncoimmunology 2019;8(9):e1621677
The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation.
Wu N, Nguyen XN, Wang L, Appourchaux R, Zhang C, Panthu B, Gruffat H, Journo C, Alais S, Qin J, Zhang N, Tartour K, Catez F, Mahieux R, Ohlmann T, Liu M, Du B, Cimarelli A
PLoS pathogens 2019 Oct;15(10):e1008093
PLoS pathogens 2019 Oct;15(10):e1008093
Lnc-ISG20 Inhibits Influenza A Virus Replication by Enhancing ISG20 Expression.
Chai W, Li J, Shangguan Q, Liu Q, Li X, Qi D, Tong X, Liu W, Ye X
Journal of virology 2018 Aug 15;92(16)
Journal of virology 2018 Aug 15;92(16)
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The ISG20 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ISG20. This antibody recognizes human, mouse, rat antigen. The ISG20 antibody has been validated for the following applications: ELISA, WB analysis.