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- References [14]
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- Immunohistochemistry [2]
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- Product number
- 15328-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15328-1-AP, RRID:AB_2187099
- Product name
- SFRP4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SFRP4 antibody (Cat. #15328-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references New treatment strategies for uterine sarcoma using secreted frizzled‑related proteins.
Spatial transcriptomics reveals prognosis-associated cellular heterogeneity in the papillary thyroid carcinoma microenvironment.
Fibroblast Subpopulations in Systemic Sclerosis: Functional Implications of Individual Subpopulations and Correlations with Clinical Features.
Short peptide domains of the Wnt inhibitor sFRP4 target ovarian cancer stem cells by neutralizing the Wnt β-catenin pathway, disrupting the interaction between β-catenin and CD24 and suppressing autophagy.
Effect of nanoparticle-mediated delivery of SFRP4 siRNA for treating Dupuytren disease.
SFRP4 Is a Potential Biomarker for the Prognosis and Immunotherapy for Gastric Cancer.
Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis.
Myofibroblast transcriptome indicates SFRP2(hi) fibroblast progenitors in systemic sclerosis skin.
Effects of SFRP4 overexpression on the production of adipokines in transgenic mice.
SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma.
SFRP4 Is a Negative Regulator of Ovarian Follicle Development and Female Fertility.
Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity.
SFRP4 gene expression is increased in aggressive prostate cancer.
Expression profiling of prostate cancer tissue delineates genes associated with recurrence after prostatectomy.
Kagawa T, Mineda A, Nakagawa T, Shinohara A, Arakaki R, Inui H, Noguchi H, Yoshida A, Kinouchi R, Yamamoto Y, Yoshida K, Kaji T, Nishimura M, Iwasa T
Experimental and therapeutic medicine 2024 May;27(5):231
Experimental and therapeutic medicine 2024 May;27(5):231
Spatial transcriptomics reveals prognosis-associated cellular heterogeneity in the papillary thyroid carcinoma microenvironment.
Yan K, Liu QZ, Huang RR, Jiang YH, Bian ZH, Li SJ, Li L, Shen F, Tsuneyama K, Zhang QL, Lian ZX, Guan H, Xu B
Clinical and translational medicine 2024 Mar;14(3):e1594
Clinical and translational medicine 2024 Mar;14(3):e1594
Fibroblast Subpopulations in Systemic Sclerosis: Functional Implications of Individual Subpopulations and Correlations with Clinical Features.
Zhu H, Luo H, Skaug B, Tabib T, Li YN, Tao Y, Matei AE, Lyons MA, Schett G, Lafyatis R, Assassi S, Distler JHW
The Journal of investigative dermatology 2024 Jun;144(6):1251-1261.e13
The Journal of investigative dermatology 2024 Jun;144(6):1251-1261.e13
Short peptide domains of the Wnt inhibitor sFRP4 target ovarian cancer stem cells by neutralizing the Wnt β-catenin pathway, disrupting the interaction between β-catenin and CD24 and suppressing autophagy.
Sundaram SM, Varier L, Fathima KZ, Dharmarajan A, Warrier S
Life sciences 2023 Mar 1;316:121384
Life sciences 2023 Mar 1;316:121384
Effect of nanoparticle-mediated delivery of SFRP4 siRNA for treating Dupuytren disease.
Jin R, Zhu W, Xu J, Gu J, Deng A
Gene therapy 2023 Feb;30(1-2):31-40
Gene therapy 2023 Feb;30(1-2):31-40
SFRP4 Is a Potential Biomarker for the Prognosis and Immunotherapy for Gastric Cancer.
Yu P, He W, Zhang Y, Hu C, Wu Y, Wang Y, Bao Z, Xia Y, Zhang R, Cao M, Yuan L, Cheng X, Xu Z
Journal of oncology 2022;2022:8829649
Journal of oncology 2022;2022:8829649
Identification of Underlying Hub Genes Associated with Hypertrophic Cardiomyopathy by Integrated Bioinformatics Analysis.
Ma Z, Wang X, Lv Q, Gong Y, Xia M, Zhuang L, Lu X, Yang Y, Zhang W, Fu G, Ye Y, Lai D
Pharmacogenomics and personalized medicine 2021;14:823-837
Pharmacogenomics and personalized medicine 2021;14:823-837
Myofibroblast transcriptome indicates SFRP2(hi) fibroblast progenitors in systemic sclerosis skin.
Tabib T, Huang M, Morse N, Papazoglou A, Behera R, Jia M, Bulik M, Monier DE, Benos PV, Chen W, Domsic R, Lafyatis R
Nature communications 2021 Jul 19;12(1):4384
Nature communications 2021 Jul 19;12(1):4384
Effects of SFRP4 overexpression on the production of adipokines in transgenic mice.
Zhang Y, Guan H, Fu Y, Wang X, Bai L, Zhao S, Liu E
Adipocyte 2020 Dec;9(1):374-383
Adipocyte 2020 Dec;9(1):374-383
SFRP4 is a prognostic marker and correlated with Treg cell infiltration in pancreatic ductal adenocarcinoma.
Yang MW, Tao LY, Yang JY, Jiang YS, Fu XL, Liu W, Huo YM, Li J, Zhang JF, Hua R, Qin XR, Sun YW, Liu DJ
American journal of cancer research 2019;9(2):363-377
American journal of cancer research 2019;9(2):363-377
SFRP4 Is a Negative Regulator of Ovarian Follicle Development and Female Fertility.
Zamberlam G, Lapointe E, Abedini A, Rico C, Godin P, Paquet M, DeMayo FJ, Boerboom D
Endocrinology 2019 Jul 1;160(7):1561-1572
Endocrinology 2019 Jul 1;160(7):1561-1572
Differential Patterns of Secreted Frizzled-Related Protein 4 (SFRP4) in Adipocyte Differentiation: Adipose Depot Specificity.
Guan H, Zhang Y, Gao S, Bai L, Zhao S, Cheng XW, Fan J, Liu E
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):2149-2164
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(5):2149-2164
SFRP4 gene expression is increased in aggressive prostate cancer.
Sandsmark E, Andersen MK, Bofin AM, Bertilsson H, Drabløs F, Bathen TF, Rye MB, Tessem MB
Scientific reports 2017 Oct 27;7(1):14276
Scientific reports 2017 Oct 27;7(1):14276
Expression profiling of prostate cancer tissue delineates genes associated with recurrence after prostatectomy.
Mortensen MM, Høyer S, Lynnerup AS, Ørntoft TF, Sørensen KD, Borre M, Dyrskjøt L
Scientific reports 2015 Nov 2;5:16018
Scientific reports 2015 Nov 2;5:16018
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 15328-1-AP(SFRP4 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15328-1-AP(SFRP4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFRP4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SFRP4. This antibody recognizes human, mouse, rat antigen. The SFRP4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
