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- Antigen structure
- References [10]
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- Western blot [1]
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- Product number
- 10326-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10326-1-AP, RRID:AB_2208005
- Product name
- TRIM32 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRIM32 antibody (Cat. #10326-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ubiquitin ligase TRIM32 promotes dendrite arborization by mediating degradation of the epigenetic factor CDYL.
Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence.
Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis.
A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation.
Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.
Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis.
TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1.
TRIM32 promotes cell proliferation and invasion by activating β-catenin signalling in gastric cancer.
Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component.
Liu L, Liu TT, Xie GG, Zhu XQ, Wang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22087
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22087
Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence.
Garcia-Garcia J, Overå KS, Khan W, Sjøttem E
PloS one 2021;16(5):e0251279
PloS one 2021;16(5):e0251279
Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.
Zhu JW, Jia WQ, Zhou H, Li YF, Zou MM, Wang ZT, Wu BS, Xu RX
Frontiers in aging neuroscience 2021;13:697494
Frontiers in aging neuroscience 2021;13:697494
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis.
Wilson MM, Callens C, Le Gallo M, Mironov S, Ding Q, Salamagnon A, Chavarria TE, Viel R, Peasah AD, Bhutkar A, Martin S, Godey F, Tas P, Kang HS, Juin PP, Jetten AM, Visvader JE, Weinberg RA, Attanasio M, Prigent C, Lees JA, Guen VJ
Science advances 2021 Oct 29;7(44):eabf6063
Science advances 2021 Oct 29;7(44):eabf6063
A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation.
Li S, Zhang L, Zhang G, Shangguan G, Hou X, Duan W, Xi Y, Xu N, Zhang B, Dong J, Wang Y, Cui W, Chen S
iScience 2021 Nov 19;24(11):103296
iScience 2021 Nov 19;24(11):103296
Knockdown of TRIM32 inhibits tumor growth and increases the therapeutic sensitivity to temozolomide in glioma in a p53-dependent and -independent manner.
Cai Y, Gu WT, Cheng K, Jia PF, Li F, Wang M, Zhang WF, Qiu JT, Wu ZB, Zhao WG
Biochemical and biophysical research communications 2021 Apr 23;550:134-141
Biochemical and biophysical research communications 2021 Apr 23;550:134-141
Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis.
Koehler S, Kuczkowski A, Kuehne L, Jüngst C, Hoehne M, Grahammer F, Eddy S, Kretzler M, Beck BB, Höhfeld J, Schermer B, Benzing T, Brinkkoetter PT, Rinschen MM
Journal of the American Society of Nephrology : JASN 2020 Mar;31(3):544-559
Journal of the American Society of Nephrology : JASN 2020 Mar;31(3):544-559
TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1.
Overå KS, Garcia-Garcia J, Bhujabal Z, Jain A, Øvervatn A, Larsen KB, Deretic V, Johansen T, Lamark T, Sjøttem E
Journal of cell science 2019 Dec 2;132(23)
Journal of cell science 2019 Dec 2;132(23)
TRIM32 promotes cell proliferation and invasion by activating β-catenin signalling in gastric cancer.
Wang C, Xu J, Fu H, Zhang Y, Zhang X, Yang D, Zhu Z, Wei Z, Hu Z, Yan R, Cai Q
Journal of cellular and molecular medicine 2018 Oct;22(10):5020-5028
Journal of cellular and molecular medicine 2018 Oct;22(10):5020-5028
Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component.
Kudryashova E, Wu J, Havton LA, Spencer MJ
Human molecular genetics 2009 Apr 1;18(7):1353-67
Human molecular genetics 2009 Apr 1;18(7):1353-67
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10326-1-AP(TRIM32 antibody) at dilution of 1:500
- Sample type
- cell line
