NBP1-92273

antibody from Novus Biologicals

Targeting: POU1F1 GHF-1, PIT-1, PIT1, POU1F1a

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

NBP1-92273

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-92273, RRID:AB_11030310

Product name

Rabbit Polyclonal Pit1 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specificity of human Pit1 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

Lower ⁶⁸ Ga-DOTATOC uptake in nonfunctioning pituitary neuroendocrine tumours compared to normal pituitary gland-A proof-of-concept study.

Tjörnstrand A, Casar-Borota O, Heurling K, Schöll M, Gjertsson P, Himmelman J, Itsenko O, Ragnarsson O, Filipsson Nyström H
Clinical endocrinology 2020 Mar;92(3):222-231

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Pangenomic Classification of Pituitary Neuroendocrine Tumors.

Neou M, Villa C, Armignacco R, Jouinot A, Raffin-Sanson ML, Septier A, Letourneur F, Diry S, Diedisheim M, Izac B, Gaspar C, Perlemoine K, Verjus V, Bernier M, Boulin A, Emile JF, Bertagna X, Jaffrezic F, Laloe D, Baussart B, Bertherat J, Gaillard S, Assié G
Cancer cell 2020 Jan 13;37(1):123-134.e5

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Diagnosis, pathology, and management of TSH-secreting pituitary tumors. A single-center retrospective study of 20 patients from 1981 to 2014.

Căpraru OM, Gaillard C, Vasiljevic A, Lasolle H, Borson-Chazot F, Raverot V, Jouanneau E, Trouillas J, Raverot G
Annales d'endocrinologie 2019 Sep;80(4):216-224

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Comprehensive analysis of circulating microRNAs in plasma of patients with pituitary adenomas.

Németh K, Darvasi O, Likó I, Szücs N, Czirják S, Reiniger L, Szabó B, Krokker L, Pállinger É, Igaz P, Patócs A, Butz H
The Journal of clinical endocrinology and metabolism 2019 May 21;

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Paradoxical GH Increase During OGTT Is Associated With First-Generation Somatostatin Analog Responsiveness in Acromegaly.

Scaroni C, Albiger N, Daniele A, Dassie F, Romualdi C, Vazza G, Regazzo D, Ferraù F, Barresi V, Maffeis V, Gardiman MP, Cannavò S, Maffei P, Ceccato F, Losa M, Occhi G
The Journal of clinical endocrinology and metabolism 2019 Mar 1;104(3):856-862

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A patient with a germline SDHB mutation presenting with an isolated pituitary macroprolactinoma.

Maher M, Roncaroli F, Mendoza N, Meeran K, Canham N, Kosicka-Slawinska M, Bernhard B, Collier D, Drummond J, Skordilis K, Tufton N, Gontsarova A, Martin N, Korbonits M, Wernig F
Endocrinology, diabetes & metabolism case reports 2018;2018

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Parathyroidectomy in patients with chronic kidney disease: Impacts of different techniques on the biochemical and clinical evolution of secondary hyperparathyroidism.

Albuquerque RFC, Carbonara CEM, Martin RCT, Dos Reis LM, do Nascimento CP Júnior, Arap SS, Moysés RMA, Jorgetti V, Montenegro FLM, de Oliveira RB
Surgery 2018 Feb;163(2):381-387

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Early postoperative growth in non-functioning pituitary adenomas; A tool to tailor safe follow-up.

Øystese KA, Zucknick M, Casar-Borota O, Ringstad G, Bollerslev J
Endocrine 2017 Jul;57(1):35-45

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Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.

Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, Soldatovic I, Boricic N, Raicevic S, Pekic S, Doknic M, Miljic D, Alafuzoff I, Pontén F, Casar-Borota O
Endocrine pathology 2016 Mar;27(1):1-11

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human pituitary gland shows moderate to strong nuclear positivity in neuroendocrine cells in the anterior lobe.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human liver shows no positivity in hepatocytes as expected.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human tonsil shows no positivity in non-germinal center cells as expected.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Pit1 Antibody [NBP1-92273] - Staining of human liver, pancreas, pituitary gland and tonsil using Anti-POU1F1 antibody NBP1-92273 (A) shows similar protein distribution across tissues to independent antibody NBP2-55357 (B).