Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- MAB4294 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal IL-22R alpha 1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-22 R alpha 1 in direct ELISAs and Western blots. Shows approximately 20% cross-reactivity with recombinant human (rh) IL-22 R and no cross-reactivity with rhIL-20 R alpha , rhIL-20 R beta , or recombinant mouse IL-22BP.
- Reactivity
- Mouse
- Host
- Rat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Murine astrocytes produce IL-24 and are susceptible to the immunosuppressive effects of this cytokine.
IL-22 signaling contributes to West Nile encephalitis pathogenesis.
IL-23-mediated epidermal hyperplasia is dependent on IL-6.
Burmeister AR, Johnson MB, Yaemmongkol JJ, Marriott I
Journal of neuroinflammation 2019 Mar 2;16(1):55
Journal of neuroinflammation 2019 Mar 2;16(1):55
IL-22 signaling contributes to West Nile encephalitis pathogenesis.
Wang P, Bai F, Zenewicz LA, Dai J, Gate D, Cheng G, Yang L, Qian F, Yuan X, Montgomery RR, Flavell RA, Town T, Fikrig E
PloS one 2012;7(8):e44153
PloS one 2012;7(8):e44153
IL-23-mediated epidermal hyperplasia is dependent on IL-6.
Lindroos J, Svensson L, Norsgaard H, Lovato P, Moller K, Hagedorn PH, Olsen GM, Labuda T
The Journal of investigative dermatology 2011 May;131(5):1110-8
The Journal of investigative dermatology 2011 May;131(5):1110-8
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