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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB2770A - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-22 R alpha 1 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IL-22 R alpha 1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) IL-10, rhIL-22BP or rhIL-20 R alpha is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
Q8N6P7- Isotype
- IgG
- Antibody clone number
- 305405
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
A novel role for IL-22R1 as a driver of inflammation.
Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells.
Dalmas E, Venteclef N, Caer C, Poitou C, Cremer I, Aron-Wisnewsky J, Lacroix-Desmazes S, Bayry J, Kaveri SV, Clément K, André S, Guerre-Millo M
Diabetes 2014 Jun;63(6):1966-77
Diabetes 2014 Jun;63(6):1966-77
A novel role for IL-22R1 as a driver of inflammation.
Savan R, McFarland AP, Reynolds DA, Feigenbaum L, Ramakrishnan K, Karwan M, Shirota H, Klinman DM, Dunleavy K, Pittaluga S, Anderson SK, Donnelly RP, Wilson WH, Young HA
Blood 2011 Jan 13;117(2):575-84
Blood 2011 Jan 13;117(2):575-84
Interleukin-24 inhibits the plasma cell differentiation program in human germinal center B cells.
Maarof G, Bouchet-Delbos L, Gary-Gouy H, Durand-Gasselin I, Krzysiek R, Dalloul A
Blood 2010 Mar 4;115(9):1718-26
Blood 2010 Mar 4;115(9):1718-26
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IL-22 R alpha 1 in COLO 205 Human Cell Line by Flow Cytometry. COLO 205 human colorectal adenocarcinoma cell line was stained with Mouse Anti-Human IL-22 R alpha 1 APC-conjugated Monoclonal Antibody (Catalog # FAB2770A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
