Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15356-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15356-1-AP, RRID:AB_2178530
- Product name
- RLBP1 antibody
- Antibody type
- Polyclonal
- Description
- RLBP1 antibody (Cat. #15356-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Genetic mutation in HSF4 is associated with retinal degeneration in mice.
Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1b(-/-) Results in Selective Dim Light Visual Behavior Deficits and Provides a Screening Platform for Evaluating the Pathogenicity of Human RLBP1 Variants.
The influence of femtosecond laser intrastromal lenticules on the characteristics and maturity in tissue-engineered stem cell-derived retinal pigment epithelium sheets.
PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species.
Human iPSC-derived retinal organoids develop robust Alzheimer's disease neuropathology.
'Iterative Bleaching Extends Multiplexity' facilitates simultaneous identification of all major retinal cell types.
CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
GliaMorph: a modular image analysis toolkit to quantify Müller glial cell morphology.
Morphological, biochemical, and transcriptomic characterization of iPSC-derived human RPE cells from normal and Smith-Lemli-Opitz syndrome patients.
Determining the optimal stage for cryopreservation of human embryonic stem cell-derived retinal pigment epithelial cells.
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids.
Aberrant Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem Cells of a Retinitis Pigmentosa Patient with the PRPF6 Mutation.
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina.
A cell-penetrating CD40-TRAF2,3 blocking peptide diminishes inflammation and neuronal loss after ischemia/reperfusion.
Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics.
The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression.
CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy.
AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice.
Induction of ectopic retina-like tissue by transgenic expression of neurogenin.
Liu B, Lang Y, Li Y, Jiang M, Xue M, Jia X, Peng X, Hu Y
Experimental eye research 2025 May;254:110316
Experimental eye research 2025 May;254:110316
Germline Disruption of Retinal Pigment Epithelium-Expressed Zebrafish rlbp1b(-/-) Results in Selective Dim Light Visual Behavior Deficits and Provides a Screening Platform for Evaluating the Pathogenicity of Human RLBP1 Variants.
Fehilly JD, McCann T, Ruddin G, Kaylor JJ, Grenville H, Ward R, Wynne K, Sánchez AG, Strachan E, Travis GH, Collery RF, Kennedy BN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70754
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jun 30;39(12):e70754
The influence of femtosecond laser intrastromal lenticules on the characteristics and maturity in tissue-engineered stem cell-derived retinal pigment epithelium sheets.
Jianing G, Zhanyu S, Yini W, Yuexi C, Zekai C, Shengguo L, Chengcheng D, Wang S, Kangjun L, Shibo T, Jiansu C
Stem cell research & therapy 2025 Jun 20;16(1):316
Stem cell research & therapy 2025 Jun 20;16(1):316
PHOSPHO1 Suppresses Ferroptosis in Retinal Pigment Epithelial Cells by Reducing the Levels of Phosphatidylethanolamine Molecular Species.
Chen Z, Zhu X, Lu MM, Ou Q, Wang X, Zhao Z, Shen Q, Wang Q, Wang Z, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Jin X, Bi Y, Lu L, Xu GT, Tian H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2505359
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(28):e2505359
Human iPSC-derived retinal organoids develop robust Alzheimer's disease neuropathology.
James E, Vielle A, Cusato K, Li H, Lee B, Parween S, Howell A, Johnson NR, Chial HJ, Potter H, Vergara MN
Frontiers in cellular neuroscience 2024;18:1340448
Frontiers in cellular neuroscience 2024;18:1340448
'Iterative Bleaching Extends Multiplexity' facilitates simultaneous identification of all major retinal cell types.
Kothurkar AA, Patient GS, Noel NCL, Krzywańska AM, Carr BJ, Chu CJ, MacDonald RB
Journal of cell science 2024 Dec 1;137(23)
Journal of cell science 2024 Dec 1;137(23)
CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
Vos S, Aaron R, Weng M, Daw J, Rodriguez-Rivera E, Subauste CS
Investigative ophthalmology & visual science 2023 Jun 1;64(7):17
Investigative ophthalmology & visual science 2023 Jun 1;64(7):17
GliaMorph: a modular image analysis toolkit to quantify Müller glial cell morphology.
Kugler E, Bravo I, Durmishi X, Marcotti S, Beqiri S, Carrington A, Stramer B, Mattar P, MacDonald RB
Development (Cambridge, England) 2023 Feb 15;150(3)
Development (Cambridge, England) 2023 Feb 15;150(3)
Morphological, biochemical, and transcriptomic characterization of iPSC-derived human RPE cells from normal and Smith-Lemli-Opitz syndrome patients.
Farkas MH, Skelton LA, Ramachandra-Rao S, Au E, Fliesler SJ
Molecular vision 2022;28:394-411
Molecular vision 2022;28:394-411
Determining the optimal stage for cryopreservation of human embryonic stem cell-derived retinal pigment epithelial cells.
Zhang T, Huang X, Liu S, Bai X, Zhu X, Clegg DO, Jiang M, Sun X
Stem cell research & therapy 2022 Sep 5;13(1):454
Stem cell research & therapy 2022 Sep 5;13(1):454
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Zhu X, Chen Z, Wang L, Ou Q, Feng Z, Xiao H, Shen Q, Li Y, Jin C, Xu JY, Gao F, Wang J, Zhang J, Zhang J, Xu Z, Xu GT, Lu L, Tian H
Cell death & disease 2022 Sep 12;13(9):785
Cell death & disease 2022 Sep 12;13(9):785
Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration.
Tian H, Chen Z, Zhu X, Ou Q, Wang Z, Wu B, Xu JY, Jin C, Gao F, Wang J, Zhang J, Zhang J, Lu L, Xu GT
iScience 2022 Oct 21;25(10):105050
iScience 2022 Oct 21;25(10):105050
PAX6-positive microglia evolve locally in hiPSC-derived ocular organoids.
Shiraki N, Maruyama K, Hayashi R, Oguchi A, Murakawa Y, Katayama T, Takigawa T, Sakimoto S, Quantock AJ, Tsujikawa M, Nishida K
Stem cell reports 2022 Feb 8;17(2):221-230
Stem cell reports 2022 Feb 8;17(2):221-230
Aberrant Retinal Pigment Epithelial Cells Derived from Induced Pluripotent Stem Cells of a Retinitis Pigmentosa Patient with the PRPF6 Mutation.
Liang Y, Tan F, Sun X, Cui Z, Gu J, Mao S, Chan HF, Tang S, Chen J
International journal of molecular sciences 2022 Aug 12;23(16)
International journal of molecular sciences 2022 Aug 12;23(16)
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina.
Martins RR, Zamzam M, Tracey-White D, Moosajee M, Thummel R, Henriques CM, MacDonald RB
Aging cell 2022 Apr;21(4):e13597
Aging cell 2022 Apr;21(4):e13597
A cell-penetrating CD40-TRAF2,3 blocking peptide diminishes inflammation and neuronal loss after ischemia/reperfusion.
Portillo JC, Yu JS, Hansen S, Kern TS, Subauste MC, Subauste CS
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21412
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Mar;35(3):e21412
Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics.
Jan TA, Eltawil Y, Ling AH, Chen L, Ellwanger DC, Heller S, Cheng AG
Cell reports 2021 Jul 13;36(2):109358
Cell reports 2021 Jul 13;36(2):109358
The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression.
Tassoni A, Farkhondeh V, Itoh Y, Itoh N, Sofroniew MV, Voskuhl RR
Scientific reports 2019 Jul 10;9(1):10010
Scientific reports 2019 Jul 10;9(1):10010
CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy.
Portillo JC, Lopez Corcino Y, Miao Y, Tang J, Sheibani N, Kern TS, Dubyak GR, Subauste CS
Diabetes 2017 Feb;66(2):483-493
Diabetes 2017 Feb;66(2):483-493
AAV-mediated RLBP1 gene therapy improves the rate of dark adaptation in Rlbp1 knockout mice.
Choi VW, Bigelow CE, McGee TL, Gujar AN, Li H, Hanks SM, Vrouvlianis J, Maker M, Leehy B, Zhang Y, Aranda J, Bounoutas G, Demirs JT, Yang J, Ornberg R, Wang Y, Martin W, Stout KR, Argentieri G, Grosenstein P, Diaz D, Turner O, Jaffee BD, Police SR, Dryja TP
Molecular therapy. Methods & clinical development 2015;2:15022
Molecular therapy. Methods & clinical development 2015;2:15022
Induction of ectopic retina-like tissue by transgenic expression of neurogenin.
Yan RT, He L, Zhan W, Wang SZ
PloS one 2015;10(1):e0116171
PloS one 2015;10(1):e0116171
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse eye tissue were subjected to SDS PAGE followed by western blot with 15356-1-AP(RLBP1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human eye using 15356-1-AP(RLBP1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The RLBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RLBP1. This antibody recognizes human, mouse, rat antigen. The RLBP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.