Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10337-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10337-1-AP, RRID:AB_2139365
- Product name
- MAD2L1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MAD2L1 antibody (Cat. #10337-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Melatonin promotes in vitro maturation of vitrified-warmed mouse GV oocytes potentially by modulating MAD2 protein expression of SAC component through MTRs.
Loss of centromeric RNA activates the spindle assembly checkpoint in mammalian female meiosis I.
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Septin 4 controls CCNB1 stabilization via APC/CCDC20 during meiotic G2/M transition in mouse oocytes.
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.
miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells.
ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint.
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
MPHOSPH1: a potential therapeutic target for hepatocellular carcinoma.
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Expression of the mitotic-arrest deficiency 2 is associated with chemotherapy resistance in ovarian serous adenocarcinoma.
Expression of mitotic-arrest deficiency 2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer.
Mitotic arrest deficiency 2 induces carcinogenesis in mucinous ovarian tumors.
Mitotic arrest defective protein 2 expression abnormality and its clinicopathologic significance in human osteosarcoma.
Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
Yang J, Guo S, Pan B, Qazi IH, Qin J, Zang S, Han H, Meng Q, Zhou G
Cryobiology 2021 Oct;102:82-91
Cryobiology 2021 Oct;102:82-91
Loss of centromeric RNA activates the spindle assembly checkpoint in mammalian female meiosis I.
Wu T, Lane SIR, Morgan SL, Tang F, Jones KT
The Journal of cell biology 2021 Oct 4;220(10)
The Journal of cell biology 2021 Oct 4;220(10)
Identification of Overexpressed Genes in Malignant Pleural Mesothelioma.
Morani F, Bisceglia L, Rosini G, Mutti L, Melaiu O, Landi S, Gemignani F
International journal of molecular sciences 2021 Mar 8;22(5)
International journal of molecular sciences 2021 Mar 8;22(5)
Septin 4 controls CCNB1 stabilization via APC/CCDC20 during meiotic G2/M transition in mouse oocytes.
Chen L, Ouyang YC, Li J, Qiao JY, Gu LJ, Wang ZB, Hou Y, Schatten H, Sun QY
Journal of cellular physiology 2021 Jun 30;
Journal of cellular physiology 2021 Jun 30;
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I.
Zhou C, Miao Y, Cui Z, ShiYang X, Zhang Y, Xiong B
Science advances 2020 Apr;6(15):eaax3969
Science advances 2020 Apr;6(15):eaax3969
miR-30a-3p Targets MAD2L1 and Regulates Proliferation of Gastric Cancer Cells.
Wang Y, Wang F, He J, Du J, Zhang H, Shi H, Chen Y, Wei Y, Xue W, Yan J, Feng Y, Gao Y, Li D, Han J, Zhang J
OncoTargets and therapy 2019;12:11313-11324
OncoTargets and therapy 2019;12:11313-11324
ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint.
Yuan F, Jin X, Li D, Song Y, Zhang N, Yang X, Wang L, Zhu WG, Tian C, Zhao Y
Nucleic acids research 2019 Sep 5;47(15):8096-8110
Nucleic acids research 2019 Sep 5;47(15):8096-8110
Nucleoporin35 is a novel microtubule associated protein functioning in oocyte meiotic spindle architecture.
Chen F, Jiao XF, Zhang JY, Wu D, Ding ZM, Wang YS, Miao YL, Huo LJ
Experimental cell research 2018 Oct 15;371(2):435-443
Experimental cell research 2018 Oct 15;371(2):435-443
KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells.
Zhu ZC, Liu JW, Li K, Zheng J, Xiong ZQ
Oncogene 2018 May;37(22):2936-2952
Oncogene 2018 May;37(22):2936-2952
MPHOSPH1: a potential therapeutic target for hepatocellular carcinoma.
Liu X, Zhou Y, Liu X, Peng A, Gong H, Huang L, Ji K, Petersen RB, Zheng L, Huang K
Cancer research 2014 Nov 15;74(22):6623-34
Cancer research 2014 Nov 15;74(22):6623-34
Probing the cell death signaling pathway of HepG2 cell line induced by copper-1,10-phenanthroline complex.
Wu J, Chen W, Yin Y, Zheng Z, Zou G
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2014 Jun;27(3):445-58
Expression of the mitotic-arrest deficiency 2 is associated with chemotherapy resistance in ovarian serous adenocarcinoma.
Nakano Y, Sumi T, Teramae M, Morishita M, Fukuda T, Terada H, Yoshida H, Matsumoto Y, Yasui T, Ishiko O
Oncology reports 2012 Oct;28(4):1200-4
Oncology reports 2012 Oct;28(4):1200-4
Expression of mitotic-arrest deficiency 2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer.
Morishita M, Sumi T, Nakano Y, Teramae M, Fukuda T, Nobeyama H, Yoshida H, Matsumoto Y, Yasui T, Ishiko O
Experimental and therapeutic medicine 2012 Feb;3(2):341-346
Experimental and therapeutic medicine 2012 Feb;3(2):341-346
Mitotic arrest deficiency 2 induces carcinogenesis in mucinous ovarian tumors.
Nakano Y, Sumi T, Morishita M, Fukuda T, Nobeyama H, Yoshida H, Matsumoto Y, Yasui T, Ishiko O
Oncology letters 2012 Feb;3(2):281-286
Oncology letters 2012 Feb;3(2):281-286
Mitotic arrest defective protein 2 expression abnormality and its clinicopathologic significance in human osteosarcoma.
Yu L, Guo WC, Zhao SH, Tang J, Chen JL
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Mar;118(3):222-9
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2010 Mar;118(3):222-9
Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.
He F, Mo L, Zheng XY, Hu C, Lepor H, Lee EY, Sun TT, Wu XR
Cancer research 2009 Dec 15;69(24):9413-21
Cancer research 2009 Dec 15;69(24):9413-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10337-1-AP(MAD2L1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MAD2L1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MAD2L1. This antibody recognizes human, mouse, rat antigen. The MAD2L1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.