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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 12676-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12676-1-AP, RRID:AB_2058675
- Product name
- BBS3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BBS3 antibody (Cat. #12676-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hedgehog signalling is involved in acquired resistance to KRAS(G12C) inhibitors in lung cancer cells.
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia.
Absence of BBSome function leads to astrocyte reactivity in the brain.
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Bardet-Biedl syndrome 3 regulates the development of cranial base midline structures.
Basal body proteins regulate Notch signaling through endosomal trafficking.
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Lee C, Yi J, Park J, Ahn B, Won YW, Jeon J, Lee BJ, Cho WJ, Park JW
Cell death & disease 2024 Jan 16;15(1):56
Cell death & disease 2024 Jan 16;15(1):56
ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane.
Fujisawa S, Qiu H, Nozaki S, Chiba S, Katoh Y, Nakayama K
Biology open 2021 Sep 15;10(9)
Biology open 2021 Sep 15;10(9)
Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.
Duan S, Li H, Zhang Y, Yang S, Chen Y, Qiu B, Huang C, Wang J, Li J, Zhu X, Yan X
The EMBO journal 2021 Jan 15;40(2):e105499
The EMBO journal 2021 Jan 15;40(2):e105499
Requirement of IFT-B-BBSome complex interaction in export of GPR161 from cilia.
Nozaki S, Castro Araya RF, Katoh Y, Nakayama K
Biology open 2019 Sep 17;8(9)
Biology open 2019 Sep 17;8(9)
Absence of BBSome function leads to astrocyte reactivity in the brain.
Singh M, Garrison JE, Wang K, Sheffield VC
Molecular brain 2019 May 9;12(1):48
Molecular brain 2019 May 9;12(1):48
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.
Hsu Y, Garrison JE, Kim G, Schmitz AR, Searby CC, Zhang Q, Datta P, Nishimura DY, Seo S, Sheffield VC
PLoS genetics 2017 Oct;13(10):e1007057
PLoS genetics 2017 Oct;13(10):e1007057
Bardet-Biedl syndrome 3 regulates the development of cranial base midline structures.
Kawasaki M, Izu Y, Hayata T, Ideno H, Nifuji A, Sheffield VC, Ezura Y, Noda M
Bone 2017 Aug;101:179-190
Bone 2017 Aug;101:179-190
Basal body proteins regulate Notch signaling through endosomal trafficking.
Leitch CC, Lodh S, Prieto-Echagüe V, Badano JL, Zaghloul NA
Journal of cell science 2014 Jun 1;127(Pt 11):2407-19
Journal of cell science 2014 Jun 1;127(Pt 11):2407-19
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Humbert MC, Weihbrecht K, Searby CC, Li Y, Pope RM, Sheffield VC, Seo S
Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 27;109(48):19691-6
Proceedings of the National Academy of Sciences of the United States of America 2012 Nov 27;109(48):19691-6
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12676-1-AP(BBS3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-BBS3 (IP:12676-1-AP, 3ug; Detection:12676-1-AP 1:600) with rat brain tissue lysate 5200ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 12676-1-AP(BBS3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 12676-1-AP(BBS3 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
