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- Antibody Data
- Antigen structure
- References [1507]
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- Immunohistochemistry [2]
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- Product number
- 14695-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14695-1-AP, RRID:AB_2082037
- Product name
- Collagen Type I antibody
- Antibody type
- Polyclonal
- Description
- Collagen Type I antibody (Cat. #14695-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, human, pig, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolomics Reveals the Anti-hepatic Fibrosis Mechanisms of Pueraria lobata (Willd.) Ohwi Extract and Potential Metabolites Alterations.
PTPN1 Regulation via YBX1-PTBP1 Interaction Promotes Fibroblast Activation and Fibrotic Remodeling in the Lung.
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Imperatorin Alleviates Intestinal Fibrosis by Suppressing AIM2-mediated GSDMD Pyroptosis in Macrophages.
Berberine Ameliorates Diabetic Kidney Disease by Modulating Macrophage Polarization via Inhibiting IL-17A Signaling.
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration.
Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy.
SIRT3-mediated deacetylation of FoxM1 prevents pulmonary fibrosis via modulating the activation of pulmonary fibroblasts.
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
Propofol Exerted an Anti-Asthmatic Effect by Attenuating Extracellular Matrix Deposition and Viability of Airway Smooth Muscle Cells.
Pharmacodynamic evaluation and mechanism study of cord blood nucleated cell extract in the treatment of rheumatoid arthritis.
Endothelial Hippo pathway regulates the neutrophil niche and lung fibrosis.
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
Cascade Therapy of Periodontitis via Sequential Release of Ribosome-Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF-Based System.
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5-Dependent RNA Demethylation.
Identification and Validation of MTFP1 as a Mitochondrial Target Restoring Dynamics and ECM Remodeling in Acute Myocardial Infarction.
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
TWIST1-Mediated Induction of AEBP1 in Fibroblast-Like Synoviocytes Activates Transforming Growth Factor β Signaling to Drive Angiogenesis and Promote Rheumatoid Arthritis.
Development of Intervertebral Disc Organoids through Directed Differentiation of Mesenchymal Stem Cells and Hierarchical 3D Printing.
A Biocompatible CMCHMA/F127DA Hydrogel with ROS-Scavenging Activity Prevents Postoperative Peritoneal Adhesions.
Time-Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism.
Sexual dimorphism in keratoconus: transcriptomic and hormonal mechanisms underlying stromal remodelling.
Hydrogen sulfide ameliorates oxalate crystal-related renal injury via inhibiting the activation of NOD-like receptor thermal protein domain associated protein 3 inflammasome in mice.
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
Design, synthesis, and anti-liver fibrosis activity of novel non-steroidal vitamin D receptor agonists based on phenyl-indole scaffold.
Microfluidic Encapsulation of Genetically Engineered Bone-marrow-derived Mesenchymal Stem Cells for Bone Defect Healing.
Lipotoxic hepatocyte-derived UBQLN1-enriched small extracellular vesicles activate hepatic stellate cells to promote hepatic fibrosis.
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Helicobacter pylori-secreted outer membrane vesicles induce bone loss and accelerate osteoporosis pathogenesis in mice by regulating gut microbiota and autophagy.
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Hyperoside stabilizes ACAT1 to promote fatty acid oxidation and attenuate kidney fibrosis via the L-carnitine-SIRT3 axis.
Adhesion molecule with Ig-like domain 1 regulates stability of carotid plaque via TGFβ/Smad signaling pathway by interaction with TGFRII.
Exosomal miRNA let-7i-5p alleviates asthma triggered by RSV-induced exosomes by regulating dendritic cell autophagy via the MITF/DAP1/P70S6K pathway.
CACNB2 overexpression suppresses atrial fibroblast activation and atrial fibrosis to mitigate atrial fibrillation.
Asymmetrical paravertebral muscles fibrosis causes progression of adolescent idiopathic scoliosis via myostatin signalling in fibro-adipogenic progenitors.
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
Comparing Effects of Short- and Long-Term Exposure of Cigarette Smoke Extract on Human Vocal Fold Fibroblasts.
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation.
7,8-Dihydroxyflavone Suppresses Experimental Pulmonary Fibrosis by Inhibiting Fibroblast-to-Myofibroblast Transformation and Epithelial-Mesenchymal Transition.
SLPI⁺ AT2-Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche.
Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell.
The therapeutic potential of pirfenidone in alleviating fibrosis and restoring ovarian function in a novel ovarian endometriosis mouse model.
Integrating BMSC-inlaid GelMA hydrogels and melatonin-loaded PLGA microspheres into silk fibroin/nanohydroxyapatite scaffolds to repair osteoporotic bone defects.
Adolescent high fructose consumption induces cardiac dysfunction in adulthood via elevated histone acetylation.
Design of RGD-functionalized GSH-responsive pegylated polymeric protacs for selective BRD4 degradation and EndMT-driven cardiac fibrosis inhibition.
Mechanically heterogeneous hydrogel with cell-programmed network restructuring promotes tissue regeneration by mechano-epigenetic modulation.
Suppressing Endothelial-Mesenchymal Transition Through the Histone Deacetylase 1/GATA Binding Protein 4 Pathway: The Mechanism of Protocatechuic Acid Against Myocardial Fibrosis Revealed by an Integrated Study.
Establishment of a three-dimensional in vitro peri-implant bone-mucosa composite model.
Development of a Gelatin-Based Composite Hydrogel Powder with Kaolin and Sr-Doped Hydroxyapatite for Dual Hemostatic and Osteogenic Potential.
Guiqi Yishen granule alleviates obstructive nephropathy-induced renal fibrosis by targeting PI3K/AKT signaling pathway.
Potential regulators and metabolic networks of muscle fatty infiltration: genomic and radiomics investigation based on 33 300 participants.
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Polystyrene nanoplastics-induced lung epithelial cells ferroptosis promotes pulmonary fibrosis via YY1/FTL axis.
Betamethasone injection at different stages showing different effect on tendon-to-bone healing in a rat rotator cuff tear model.
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis.
Thymoquinone Protects Against Cardiac Hypertrophy via PPAR-γ/PI3K/Akt Pathway.
Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models.
Engineered probiotics for the in vivo mitigation of waterborne uranium toxicity and bioaccumulation.
Engineered Gadolinium-Decorated Magnetic Resonance Nanoprobes for Enhanced Liver Fibrosis Theranostics.
Biomimetic Multilayered Gas-Foaming Scaffold with Sustained bFGF Delivery for Annulus Fibrosus Regeneration.
A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.
Autocrine Netrin-1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
Activating the Osteoblastic USP26 Pathway Alleviates Multi-Organ Fibrosis by Decreasing Insulin Resistance.
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
Targeted inhibition of RGS19 alleviates renal fibrosis by restoring autophagy and modulating immune cell infiltration.
Role of CTGF-LRP1 in impaired healing of cesarean section incisions.
PLGA nanofibers carrying rhFGF1 for the effective treatment of skin wounds in diabetic mice.
STING deficiency alleviates scar formation after glaucoma filtration surgery by suppressing p38 MAPK-induced inflammation in mice.
Synergistic microenvironment therapy: a dual-function nanogel of supramolecular collagen ll-mimetic matrix and antioxidant MXene for attenuating intervertebral disc degeneration.
Graphene oxide/sodium alginate/silk fibroin extracellular matrix-like sponge for acellular and growth factor-free bone regeneration.
Identification and validation of the protective gene BCAT2 related to amino acid metabolism in idiopathic pulmonary fibrosis.
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Shexiang Tongxin dropping pills attenuate cardiac remodeling in myocardial infarction rats by inhibiting Glycolysis via ITGB2 methylation.
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
An engineered triple-network alginate/gelatin hydrogel mediates osteochondral regeneration through temporal regulation of the PI3K-AKT pathway.
Lipid-modulating hyaluronic acid hydrogel promotes chondrogenesis of osteoarthritis progenitor cells for weight-bearing cartilage repair.
Inhibitory effect of Anwulignan on the IL-36R/TLR9 signaling pathway: potential therapeutic role in hepatic fibrosis.
Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway.
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.
TRIM21 Alleviates Alcoholic Liver Fibrosis by Inhibiting Ferroptosis Through Regulation of IDO1 Ubiquitination.
Dehydroepiandrosterone alleviates pulmonary fibrosis by modulating the TLR4/NF-κB/NLRP3 signaling cascade in macrophages.
Buyang Huanwu Decoction suppresses atherosclerosis by targeting IFITM1‑mediated lipid metabolism in vascular smooth muscle cells.
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
Beryllium Sulfate-Induced Cellular Senescence via the IL-6/STAT3 Pathway to Promote Pulmonary Fibrosis.
1-O-acetylbritannilactone alleviates high-fat diet-induced fatty liver by covalently targeting NLRP3.
Biphasic Scaffolds Functionalized with Piezoelectric Nanozymes for Osteochondral Defect Regeneration.
Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study.
Targeting p97/Valosin-Containing Protein Promotes Hepatic Stellate Cell Senescence and Mitigates Liver Fibrosis.
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
GDF10 attenuates MASH progression by restoring quiescent hepatic stellate cells via competitive inhibition of TGF-β/SMAD2 signaling.
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Mechanical stretch-induced IGF2 overexpression in epidermal keratinocytes promotes hypertrophic scar formation through the IGF1R/p-c-Jun axis.
Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis.
Transcriptomic and experimental evidence confirm the potential of disulfidptosis-related signature for the early diagnosis and treatment of liver cirrhosis.
Tetrahedral Framework Nucleic Acids Inhibit Oxidative Stress and Cardiomyocyte Apoptosis in Doxorubicin-Induced Cardiotoxicity.
Ginkgolide B Alleviates LPS-Induced Inhibition of Osteogenic Differentiation in Human Periodontal Ligament Stem Cells by Suppressing the p-IκBα/NF-κB Pathway.
ShenQi ShenKang Granule Alleviates Chronic Kidney Disease by Inhibiting the PI3K/AKT/mTOR Pathway and Restoring Autophagy Flux and Mitochondrial Integrity.
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Succinate Facilitates CD4(+) T Cell Infiltration and CCL1 Production to Promote Myofibroblast Activation and Renal Fibrosis in UUO Mice.
SIRT1 Enhancement is Required for the Induction of Anti-Inflammatory Effect of Micheliolide in Carbon Tetrachloride Induced Liver Fibrosis in Mice.
Cannabidiol Alleviates Intestinal Fibrosis in Mice with Ulcerative Colitis by Regulating Transforming Growth Factor Signaling Pathway.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Tibetan medicine Pa Zhu Wan ameliorates carbon tetrachloride-induced liver fibrosis in rats by regulating the TGF-β-Smad2/3 and IL-6/JAK2/STAT3 signaling pathways.
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging.
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model.
Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation.
Yiqi Qingre Gao alleviates renal fibrosis in UUO mice via PI3K/AKT pathway.
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b.
Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana extract.
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Receptor activity-modifying protein 1 regulates the differentiation of mouse skin fibroblasts by downregulating α-SMA expression via suppression of high mobility group AT-hook 1 to promote skin wound repair.
Meniscus progenitor cells combined with joint lavage promote meniscus regeneration and cartilage protection in rat models.
IGF1R promotes radiation-induced HSCs activation by regulating DNA-PKcs-mediated DNA damage repair.
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy.
Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing.
Phytochemical nanozymes reprogram redox for balanced antimicrobial and regenerative therapy in acute and chronic diabetic wounds.
The Paeonol of Total Glucosides of White Peony Regulates the Differentiation of CD4+Treg Cells through the EP300/Foxp3 Axis to Relieve Pulmonary Fibrosis in Mice.
A mouse coccygeal intervertebral disc degeneration model with tail-looping constructed using a suturing method.
Diosmetin alleviates osteoarthritis through modulating the polarization of macrophages by inhibiting the PI3K/Akt signaling pathway.
Noninsulated Microneedle Radiofrequency for Skin Rejuvenation: A Histological, Transcriptomic and Clinical Study.
Kaempferol Suppresses Mesothelial-Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF-α/COX2 Signalling Pathway.
3D-printed advanced scaffold armed with exosomes derived from human skeletal stem cell identified by single-cell RNA sequencing enhances osteochondral regeneration.
Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression.
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Self-Growing Scaffold for Spatial and Border Expansive Regeneration.
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Integrin αvβ6 mediates the effects of age-related decreases in matrix stiffness on Tenon's fibroblast activation and bleb scarring in glaucoma.
Efficacy of Encorelane in Enhancing Barrier Function and Reducing Aging Signs in Sensitive Skin.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Carbon black induced pulmonary fibrosis through piR-713551/PIWIL4 targeting THBS2 signal pathway.
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
Wu Zi Yan Zong Wan Improves Triptolide-Induced Testicular Spermatogenic Dysfunction Through the Spermatogenic Microenvironment and the PLCγ/PKC Pathway.
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery.
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
The protective role of Agrin and CAF22 in hypertensive nephropathy.
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
LINC02099 Promotes Retinal Extracellular Matrix Deposition in Diabetic Mice Via the miRNA-214-3p/CTSS Axis.
4EBP1 phosphorylation mediates TGF-β1-induced hepatic fibrosis and upregulates HIF-1α expression.
Podoplanin-TGF-β1 Autocrine Loop: Pivotal Regulator of Islet Stellate Cell Activation via Cell Deformation, Orchestrating Islet Fibrosis in Diabetes.
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
Targeting interferon regulatory factor 7 alleviates renal fibrosis by inhibiting macrophage-to-myofibroblast transition.
Proteins extracted from placenta regulate osteogenic differentiation of human mesenchymal stem cells.
Dimethyloxalylglycine regulates osteogenesis of dental pulp stem cells through PI3K/AKT signaling pathways.
Magnesium ions attenuate tendon graft fibrosis during its ligamentization after ACL reconstruction through modulation of fibroblast to myofibroblast trans-differentiation by promoting PGE2 secretion.
Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity.
CCP1 Inhibits Pulmonary Fibrosis by Suppressing Fibrotic Progression Through the EIF4B/PI3K/AKT Pathways.
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
Titanium surface modified with nanostructure mimicking the surface of natural cementum up-regulated epithelial expression of integrin β4 and enhanced the attachment of the transmucosal gingiva.
Canagliflozin-driven cellular re-differentiation and migration inhibition in vascular smooth muscle cells via PTEN upregulation.
Investigating the Antifibrotic Action of Foeniculum vulgare Root Bark Volatile Oil Through the HK2/PKM2/LDHA Pathway.
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia.
Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
Identification of lactylation-related hub genes as novel therapeutic and diagnostic targets for thoracic aortic dissection.
TNALP promotes epithelial oxidative stress and fibrosis via SIRT3-dependent mechanisms in tracheal injury.
Angiotensin (1-7) decreases the fibrotic process by modulating the TGF-β1/AKT pathway in rat corpus cavernosum smooth muscle cells.
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease.
Liver-Targeted Scutellarin Nanoemulsion Alleviates Fibrosis with Ancillary Modulation of the Gut-Liver Microbiota.
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
CAMKK2 restored mitochondrial dynamics homeostasis to alleviate pulmonary fibrosis via AMPK/PGC-1α signaling pathway in lung fibroblasts.
Isolation and characterisation of AFP(+)/DLK1(+) double-positive hepatic stem/progenitor-like cells from fibrotic partial hepatectomy model.
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
Deletion of cardiac fibroblast growth factor-23 beneficially impacts myocardial energy metabolism in left ventricular hypertrophy.
miR-34c-5p targets Notch2 to promote fracture healing.
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury.
Hesperetin alleviates liver fibrosis by improving intestinal microbiota composition and regulating hepatic stellate cell autophagy.
Isorhapontigenin alleviates pulmonary fibrosis by inhibiting oxidative stress-induced senescence via STAT3/PRDX2 signals in alveolar epithelial cells.
Faecalibacterium prausnitzii alleviates Graves' orbitopathy by modulating short-chain fatty acid (SCFA) metabolism and inhibiting orbital fibrosis and adipogenesis.
Holistic regulation of the diabetic osteo-microenvironment via NIR-II nanocarriers with dual NO/pH responsiveness for enhanced bone regeneration.
YOD1 mediates isoproterenol-induced cardiac remodeling by deubiquitinating PKM2 and reducing PKM2 tetramerization in cardiomyocytes.
Protamine-loaded quaternized chitosan hydrogel dressing featuring antibacterial and antioxidant properties for promoting postoperative periodontal wound healing.
Bispecific aptamers target thyrotropin receptor (TSHR) and insulin growth factor-1 receptor (IGF-1R) for the improvement of orbital fibroblasts activation in the treatment of thyroid-associated ophthalmopathy.
Porous chitin nanofibers combined with adipose-derived stem cells promote diabetic wound healing via PPAR-γ activation.
Osteoclasts drive bone formation in ectopic and orthotopic environments.
Timosaponin B- II Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via PI3K/AKT/GSK3β Signaling Pathway.
Autophagic degradation of SQSTM1 enables fibroblast activation to accelerate wound healing.
An Ile to Met polymorphism in ADCY9 promotes airway obstruction and remodeling in asthma.
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
3D Differentiation of Bone-Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting.
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis.
High-throughput Generation of Collagen Microbeads for Extracellular Vesicle Production and Therapeutic Delivery.
IGF1-mediated mesenchymal-endothelial transition as a potential regulatory target in calcific aortic valve disease.
Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice.
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Shenqi compound ameliorates renal fibrosis in diabetic kidney disease by inhibiting LRG1/TGF-β/Smad signaling pathway.
Directed rescue strategy for enhanced implant osteointegration in aged rats.
Reconstruction of the lymphatic system by transplantation of a centrifuge-based bioengineered lymphatic tissue.
Loss of LCAT function aggravates metabolic-associated steatohepatitis (MASH) in golden Syrian hamster.
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Sotagliflozin attenuates atrial oxidative stress and the susceptibility to atrial fibrillation by activating the NRF2/HO-1 pathway.
The influences of antihistamine on liver fibrosis, vasoresponsiveness, and portosystemic shunting in bile duct-ligated cirrhotic rats.
Poricoic Acid A attenuated TGF-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells through SPRY2/ERK signaling pathway.
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Radiation Induces Pericyte-Myofibroblast Transition.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis.
A Keap1-recruiting BRD4 degrader offers a single-molecular polypharmacology approach for the treatment of metabolic dysfunction-associated steatohepatitis.
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
Porcine plasma protein cold-set hydrogel crosslinked by genipin and the immunomodulatory, proliferation promoting and scar-remodeling in wound healing.
Network pharmacology combined with experimental analysis to explore the mechanism of the XinShuaiNing formula on heart failure.
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
13-Methylpalmatine alleviates bleomycin-induced pulmonary fibrosis by suppressing the ITGA5/TGF-β/Smad signaling pathway.
Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization.
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Pulmonary Injury Induced via Metal-Organic Frameworks (MOFs): ROS Generation and Inflammatory Responses Mediated by HKUST-1.
SMYD2 Promotes Renal Tubular Cell Apoptosis and Chronic Kidney Disease Following Cisplatin Nephrotoxicity.
Decellularised amniotic membrane-TDSCs composite promotes Achilles tendon healing.
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
LncRNA SYISL promotes fibroblast myofibroblast transition via miR-23a-mediated TRIOBP regulation.
Superoxide Anion (O(2)(-•)) Leading to Pulmonary Toxicity of Metal-Organic Frameworks (MOFs).
Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis.
Identifying and Targeting Key Driver Genes for Collagen Production within the 11q13/14 Breast Cancer Amplicon.
Vascular grafts with a mimetic microenvironment extracted from extracellular matrix of adipocytes can promote endothelialization in vivo.
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
Exploring the wound-healing mechanism of Cayratia japonica extract: A combined experimental and network pharmacology study.
GAMG alleviates liver fibrosis through inducing ferroptosis in inflammatory macrophages via the IRF1/SLC7A11 signaling pathway.
TRPV4 as a Novel Regulator of Ferroptosis in Colon Adenocarcinoma: Implications for Prognosis and Therapeutic Targeting.
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
ADAMTS13 attenuates renal fibrosis by suppressing thrombospondin 1 mediated TGF-β1/Smad3 activation.
Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC.
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Osteomimix: A Multidimensional Biomimetic Cascade Strategy for Bone Defect Repair.
Shenmai Injection Reduces Cardiomyocyte Apoptosis Induced by Doxorubicin through miR-30a/Bcl-2.
Methacrylated silk fibroin based composite hydrogel with ROS-scavenging and osteogenic ability to orchestrate diabetic bone regeneration.
CD39 Contributes to the Ability of Cell Invasion in Heterogeneity of Colorectal Cancer.
p16INK4a Deletion Alleviated Obesity-Associated Kidney Fibrosis by Regulating Metabolic Reprogramming and the Inflammasome Pathway.
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis.
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Exosomes derived from fibroblasts in DFUs delay wound healing by delivering miR-93-5p to target macrophage ATG16L1.
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Nitazoxanide protects against heart failure with preserved ejection and metabolic syndrome induced by high-fat diet (HFD) plus L-NAME "two-hit" in mice.
Improved Black Phosphorus Nanocomposite Hydrogel for Bone Defect Repairing: Mechanisms for Advancing Osteogenesis.
Highly expressed VGLL3 in keloid fibroblasts promotes glycolysis and collagen production via the activation of Wnt/β-catenin signaling.
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Targeting the E Prostanoid Receptor EP4 Mitigates Cardiac Fibrosis Induced by β-Adrenergic Activation.
Evenly Distributed Microporous Structure and E7 Peptide Functionalization Synergistically Accelerate Osteogenesis and Angiogenesis in Engineered Periosteum.
Extracellular Mitochondrial-Derived Vesicles Affect the Progression of Diabetic Foot Ulcer by Regulating Oxidative Stress and Mitochondrial Dysfunction.
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA(+) macrophages contribute to atherosclerotic plaque formation.
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Molecular mechanisms and therapeutic targets in glioblastoma multiforme: network and single-cell analyses.
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis.
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition.
Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway.
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts.
Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via circPRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial-Mesenchymal Transition.
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Harnessing Anti-Inflammatory and Regenerative Potential: GelMA Hydrogel Loaded with IL-10 and Kartogenin for Intervertebral Disc Degeneration Therapy.
Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model.
Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.
Beneficial effects of Akkermansia muciniphila on benign prostatic hyperplasia and metabolic syndrome.
A thermosensitive hydrogel with synergistic stromal targeting and antitumor immunity modulation for pancreatic cancer immunotherapy.
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Polyvinyl alcohol/graphene oxide/dextran hydrogel doped copper oxide modified biochar with nano-enzymatic activity and multiple synergistic effects for accelerated diabetic wound healing.
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Shuangshi Tonglin Capsule Improves Prostate Fibrosis through Nrf2/TGF-β1 Signaling Pathways.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Acetylation of H3K18 activated by p300 promotes osteogenesis in human adipose-derived mesenchymal stem cells.
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Neferine reduces synovial inflammation and cardiac complications in a collagen-induced arthritis mouse model via inhibiting NF-κB/NLRP3 inflammasome axis.
A 3D Co-Culture System Inspired by Fracture Healing Cell Interactions for Bone Tissue Engineering.
Injectable Alginate/β-TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis.
FP receptor inhibits autophagy to aggravate aging-related cardiac fibrosis through PI3K/AKT/mTOR signaling pathway.
MTFR2-Mediated Fission Drives Fatty Acid and Mitochondrial Co-Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis.
Molecular adaptations in MMP genes support lung elasticity and diving adaptations in cetaceans.
Inhibition of Matrix Metalloproteinase-7 Attenuates Subpleural Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Network pharmacology and bioinformatics analysis reveals: NXC improves cardiac lymphangiogenesis through miR-126-3p/SPRED1 regulating the VEGF-C axis to ameliorate post-myocardial infarction heart failure.
Rebastinib attenuates acute lung injury by promoting NLRP3 ubiquitination and blocking NLRP3/GSDMD signaling pathway in macrophages and protecting alveolar epithelial cells.
Notch3 enhances the synergistic effect of all-trans retinoic acid and calcipotriol in pancreatic stellate cell activation.
Celastrol alleviates esophageal stricture in rats by inhibiting NLR family pyrin domain containing 3 activation.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice.
Sequential construction of vascularized and mineralized bone organoids using engineered ECM-DNA-CPO-based bionic matrix for efficient bone regeneration.
Immune-modulated adhesive hydrogel for enhancing osteochondral graft adhesion and cartilage repair.
Mechanistic Insights Into 5'-tiRNA-His-GTG Mediated Activation of the JNK Pathway in Skin Photoaging.
The mechanism of action of GLUT1 in promoting NETs-mediated impairment of macrophage phenotypic switching based on macrophage-fibroblast interplay.
Stiffness regulates extracellular matrix synthesis in fibroblasts by DDR1-TGF-β/STAT3 mechanotransduction axis.
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
CD11b Blockade Ameliorates Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil and Monocyte Infiltration.
Exploring the molecular mechanisms through which overexpression of TET3 alleviates liver fibrosis in mice via ferroptosis in hepatic stellate cells.
Inhibition of RACK1-Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome.
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization.
Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition.
Benzothiazole amide analogues as antagonists of TRPC 6 channels: A therapeutic approach for kidney fibrosis.
Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages.
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring.
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Bioactive fraction of processed Curcumae Rhizoma-Sparganii Rhizoma anti-liver fibrosis by regulate taurine metabolism through PI3K/AKT pathway.
Maternal obesity impairs fetal brown adipogenesis by attenuating fetal FGF21 signaling.
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.
GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis.
Exploring PU.1 as a Therapeutic Target to Mitigate Oxidative Stress and Inflammation in Peritoneal Dialysis-Induced Peritoneal Fibrosis.
Blocking calcium-MYC regulatory axis inhibits early dedifferentiation of chondrocytes and contributes to cartilage regeneration.
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Dendrobium officinale-derived nanovesicles: a natural therapy for comprehensive regulation of angiogenesis, inflammation, and tissue repair to enhance skin wound healing.
Identification and analysis of extracellular matrix and epithelial-mesenchymal transition-related genes in idiopathic pulmonary fibrosis by bioinformatics analysis and experimental validation.
ALKBH5 regulates intrauterine adhesion progression through m6A dependent FABP4 mRNA stabilization and serum lipid metabolism.
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Biodegradable Zn-xY alloys with enhanced osteogenesis and angiogenesis effects for bone implant applications.
Comparison of the effects of Liraglutide, Tirzepatide, and Retatrutide on diabetic kidney disease in db/db mice.
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
Localization of α-smooth muscle actin in osteoblast differentiation during periodontal development.
Topography immune-responsive silk films for skin regeneration.
Sympathetic nerve promotes renal fibrosis by activating M2 macrophages through β2-AR-Gsa.
ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion.
Betulin gel alleviates esophageal stricture following endoscopic submucosal dissection: an animal study.
Magnesium-Impregnated Membrane Promotes Bone Regeneration in Rat Skull Defect by N-Linked Glycosylation of SPARC via MagT1.
Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis.
Single-cell RNA sequencing reveals the heterogeneity of myofibroblasts in wound repair.
Copper ions-photo dual-crosslinked alginate hydrogel for angiogenesis and osteogenesis.
The CLCA1/TMEM16A/Cl- current axis associates with H2S deficiency in diabetic kidney injury.
Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection: A natural ingredient strategy.
Exploring the molecular mechanisms for renoprotective effects of Huangkui capsule on diabetic nephropathy mice by comprehensive serum metabolomics analysis.
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
Inhibition of HIF-1α ameliorates pulmonary fibrosis by suppressing M2 macrophage polarization through PRMT1/STAT6 signals.
Adipose mesenchymal stem cell-derived extracellular vesicles alleviate renal fibrosis by reducing epithelial-mesenchymal transition via the FOXS1/Wnt/β-catenin signaling pathway.
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2.
SR9009 attenuates TGF-β1-induced renal fibrotic responses by inhibiting the NOX4/p38 signaling pathway in NRK-49F cells.
Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling.
Wenshen Xiaozheng Tang alleviates fibrosis in endometriosis by regulating differentiation and paracrine signaling of endometrium-derived mesenchymal stem cells.
Functional Characteristics of the Crosstalk Between Vocal Fold Fibroblasts and Macrophages-The Role of Vibration in Vocal Fold Inflammation.
Injectable agents for the induction of Peyronie's disease in model rats: a comparative study.
Nicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus.
Acid-Induced in Situ Phase Separation and Percolation for Constructing Bi-Continuous Phase Hydrogel Electrodes With Motion-Insensitive Property.
α-arbutin prevents UVA-induced skin photodamage via alleviating DNA damage and collagen degradation in NIH-3T3 cells.
Hyperlipidemia impairs bone repair and regeneration via miR-193a-3p/STMN1/PI3K/Akt axis.
Injectable tissue-engineered human cartilage matrix composite fibrin glue for regeneration of articular cartilage defects.
Ubiquitin-specific protease 25 improves myocardial ischemia-reperfusion injury by deubiquitinating NLRP3 and negatively regulating NLRP3 inflammasome activity in cardiomyocytes.
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Asiatic acid improves the damage of HaCaT cells induced by nitrogen mustard through inhibiting endoplasmic reticulum stress.
A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells.
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice.
Enhancing the Therapeutic Efficacy of Berberine and Quercetin Through Salt Formulation for Liver Fibrosis Treatment.
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation.
Huangqi-Danshen decoction alleviates renal fibrosis through targeting SCD1 to modulate cGAS/STING signaling.
Mesoscale orchestration of collagen-based hierarchical mineralization.
MTHFD2 stabilizes LOX expression through RNA methylation modification to promote sepsis-induced acute kidney injury progression.
Ether bond-modified lipid nanoparticles for enhancing the treatment effect of hepatic fibrosis.
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Drop-shaped microgrooves guide unidirectional cell migration for enhanced endothelialization.
CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis.
Focal Adhesion Regulation as a Strategy against Kidney Fibrosis.
Cancer-secreted exosomal miR-1246 promotes colorectal cancer liver metastasis by activating hepatic stellate cells.
The natural product-derived JM-9 alleviates high-fat diet-induced fatty liver in mice by targeting MD2.
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss.
Discovery of novel capsaicin analogs as TRPV1 inhibitors for the treatment of idiopathic pulmonary fibrosis.
Inhibition of tubular epithelial cells ferroptosis alleviates renal interstitial fibrosis by reducing lipid hydroperoxides and TGF-β/Smad signaling.
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Recombinant Humanized Collagen Enhances Secreted Protein Levels of Fibroblasts and Facilitates Rats' Skin Basement Membrane Reinforcement.
Plasma-activated solutions prevent peritoneal adhesion formation by regulating eNOS expression in mesothelial cells.
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
An Electrospun Heparin Modified Nanofiber Membrane Carrying Multiple Growth Factors for Dental Pulp Regeneration.
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
Concentrated Micronized Fat Ameliorates Skin Fibrosis in Bleomycin-Induced Murine Model and Enhances Fat Graft Survival.
Mulberry-derived carbon dots attenuate kidney fibrosis through direct inhibition of PI3K.
3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
Aldehyde Dehydrogenase 6 Family Member A1 Facilitates Ti Implant Osseointegration in Hyperlipidemia.
Hypericin-mediated photodynamic therapy promotes apoptosis and inhibits fibrosis by inducing HMOX1-mediated ferroptosis in hypertrophic scar fibroblasts.
Asiatic acid inhibits endothelial-to-mesenchymal transition in diabetic kidney disease by reducing acetyl-CoA production via targeting ACSS2.
Stellarin I: A Bioactive Cyclic Nonapeptide with Potent Anti-renal Fibrosis Activity from the Root of Stellaria yunnanensis Franch.
Myofibroblast specific knockdown of NSUN2 suppresses cardiac fibrosis post-myocardial infarction.
LIPUS promotes osteogenesis via the mcirc_9393-miR-217/326-SIRT1 axis in porous Ti6Al4V scaffolds.
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
5'tiRNA-Glu-TTC targets TRPV3 and activates the PI3K/AKT signaling pathway to modulate skin photoaging.
Bmi-1 overexpression mitigates vitamin D deficiency-induced pulmonary fibrosis via TIME pathway.
HMGB1-enhanced autophagic degradation of E-cadherin facilitates mesothelial trans-differentiation and postoperative peritoneal adhesion.
Cx43 hemichannel-mediated paracrine involves in the promotion of MSCs on skin wound healing.
Dual-functional nanovesicles simultaneously inhibit stromal fibrosis and angiogenesis to suppress cholangiocarcinoma progression.
Enhancement of drug delivery through fibroblast activation protein-targeted near-infrared photoimmunotherapy.
Fibrotic collagen-targeted delivery system blocks pancreatic intercellular crosstalk to alleviate pancreatic fibrosis.
Procyanidin B2 mitigate asthmatic airway remodeling by inhibiting TGF-β1-induced airway smooth muscle proliferation through ROS signaling.
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.
Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment.
TGF-β drives myofibroblast activation and inflammatory mediator production in vulvar lichen sclerosus.
Inhibition of GDNF-Driven Macrophage-to-Myofibroblast Transition Protects Against Colitis-Associated Intestinal Fibrosis.
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
Polo-like kinase 1 drives hypoxia-induced renal fibrosis via PTEN/PGK1-mediated glycolytic activation.
Silencing PIM1 inhibits ENO1-induced AKT activation and attenuates fibrillogenesis during spinal cord injury-induced skeletal muscle atrophy.
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Molten-Salt-Mediated Synthesis of Atomic Manganese/Cobalt Catalysts on Bioceramic Microparticles for Catalytic Anti-Osteoarthritis Treatments.
Butyrate protects against myocardial ischemia injury and cardiomyocyte pyroptosis by inhibiting MALT1-mediated Nrf2 ubiquitination and degradation.
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus.
Rehmannioside A alleviates renal inflammation and fibrosis in hypertensive nephropathy via AT1R/MAPK14/IL-17 signaling pathway.
Maimendong decoction and its active ingredient, ophiopogonin D, alleviate bleomycin-induced pulmonary fibrosis by regulating the behavior of lung fibroblasts.
Low-protein Calorie-restriction Mitigates Diabetic Mice Kidney Injury via the Gut-Kidney Axis.
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
Lysionotin attenuates bleomycin-induced pulmonary fibrosis by activating AMPK/Nrf2 pathway.
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
Eupatorium lindleyanum DC Ameliorates Carbon Tetrachloride-Induced Hepatic Inflammation and Fibrotic Response in Mice.
The protective role of ureteral stents in reducing fibrosis and preventing stricture in ureteral injuries of different severities.
NAT10 Mediates Cardiac Fibrosis Induced by Myocardial Infarction Through ac4C Modification of TGFBR1 mRNA.
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Targeted Delivery of CD34 Aptamer-Coupled Tocilizumab Microspheres for Effective Treatment of Thyroid-Associated Ophthalmopathy.
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula.
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-(13)C(5)]-glutamine metabolic flux analysis.
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway.
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice.
Circadian clock gene BMAL1 is involved in transforming growth factor β1-induced fibrotic response in NRK-49F cells.
Synergizing adaptive immunity and regenerative signals to enhance osteochondral defects repair.
Engineered Stem Cell Booster Breaks Pathological Barriers to Treat Chronic Pancreatitis.
Engineered MSCs Break Endothelial-Myofibroblast Crosstalk in Pulmonary Fibrosis: Reconstructing the Vascular Niche.
BMAL1 Regulates Collagen Production in the Myometrium and Leiomyomas.
3D bioprinted piezoelectric hydrogel synergized with LIPUS to promote bone regeneration.
Hydrogel inspired by "adobe" with antibacterial and antioxidant properties for diabetic wound healing.
A nanoemulgel formulation of acetylated Crataegus pinnatifida polysaccharide for the treatment of skin photoaging in mice.
Hepatoprotective effects of polysaccharide from Morchella esculenta are associated with activation of the AMPK/Sirt1 signaling pathway in mice with NAFLD.
circSIRT2/miR-542-3p/VASH1 axis regulates endothelial-to-mesenchymal transition (EndMT) in subretinal fibrosis in age-related macular degeneration models.
Tamibarotene directly targets the NACHT domain of NLRP3 to alleviate acute myocardial infarction.
Impact of red-lime and white-lime betel quid on oral cell lines: Cytotoxicity and effects on fibronectin and type I collagen expression.
Hypoxia amplifies arecoline-induced invasion and metastasis in oral squamous cell carcinoma - Insights into TGF-β1 signaling and collagen production.
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells.
Exercise-Mediated Mechanical Stress Promotes Osteogenic Differentiation of BMSCs Through Upregulation of Lactylation via the IER3/LDHB Axis.
Fullerol Initiates Stem Cell-Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling.
OTUD1 inhibits endometriosis fibrosis by deubiquitinating MADH7.
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway.
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation.
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Effects of Different Light Environments with Varying Spectral Composition on the Axial Lengths and Scleral Specificity Protein 1 and Collagen Type I Expression in Juvenile Guinea Pigs.
An Integrated Dual-Layer Heterogeneous Polycaprolactone Scaffold Promotes Oral Mucosal Wound Healing through Inhibiting Bacterial Adhesion and Mediating HGF-1 Behavior.
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop.
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung Injury.
Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF-β/Smad Signaling Pathway.
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Swimming alleviates myocardial fibrosis of type II diabetic rats through activating miR-34a-mediated SIRT1/PGC-1α/FNDC5 signal pathway.
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.
TAK-242 alleviates diabetic cardiomyopathy via inhibiting pyroptosis and TLR4/CaMKII/NLRP3 pathway.
Liposomes Loaded with 5-Fluorouracil Can Improve the Efficacy in Pathological Scars.
A TSHR-Targeting Aptamer in Monocytes Correlating with Clinical Activity in TAO.
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway.
Graphene Oxide Quantum Dots-Preactivated Dental Pulp Stem Cells/GelMA Facilitates Mitophagy-Regulated Bone Regeneration.
Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model.
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells.
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition.
RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation.
Deciphering m(6)A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy.
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts.
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.
Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17/Treg imbalance.
Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway.
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
A New Rat Model of Sacral Cord Injury Producing a Neurogenic Bladder and Its Functional and Mechanistic Studies.
Construction of multilayered small intestine-like tissue by reproducing interstitial flow.
IKKα-STAT3-S727 axis: a novel mechanism in DOX-induced cardiomyopathy.
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
Deficiency of geranylgeranyl biphosphate synthase in kidney tubules causes cystic kidney disease.
Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice.
Mechanosensitive Piezo1 channels promote neurogenic bladder fibrosis via regulating TGF-β1/smad and Hippo/YAP1 pathways.
Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal-organic framework nanoparticles for ischemic osteonecrosis treatment.
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.
Calcipotriol abrogates TGF-β1/pSmad3-mediated collagen 1 synthesis in pancreatic stellate cells by downregulating RUNX1.
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
Site-specific bioorthogonal regulation of bone morphogenetic protein 2 expression for effective bone regeneration.
Flexible and high-strength bioactive glass fiber membrane for bone regeneration with the aid of alkoxysilane sol spinnability.
A photothermal responsive system accelerating nitric oxide release to enhance bone repair by promoting osteogenesis and angiogenesis.
Melatonin-loaded bioactive microspheres accelerate aged bone regeneration by formation of tunneling nanotubes to enhance mitochondrial transfer.
RELA-mediated upregulation of LINC03047 promotes ferroptosis in silica-induced pulmonary fibrosis via SLC39A14.
Liraglutide Promotes Diabetic Wound Healing via Myo1c/Dock5.
The Effect of Metformin on Radiation-Induced Lung Fibrosis in Mice.
Decrease of Prolylcarboxypeptidase Dose of Aqueous Humor is Involved in the Pathogenesis of Primary Open-Angle Glaucoma via Finetuning of the Local Ocular Renin-Angiotensin System.
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Albendazole ameliorates aerobic glycolysis in myofibroblasts to reverse pulmonary fibrosis.
Non-pharmacological interventions of intermittent fasting and pulsed radiofrequency energy (PRFE) combination therapy promote diabetic wound healing.
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition.
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Construction and performance evaluation of fully biomimetic hyaline cartilage matrix scaffolds for joint defect regeneration.
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation.
CCT6A alleviates pulmonary fibrosis by inhibiting HIF-1α-mediated lactate production.
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
ADAM8 promotes alcoholic liver fibrosis through the MAPK signaling pathway.
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
NLRP3 inflammasome inhibition decreases Schistosomiasis japonica-induced granulomatous inflammation and fibrosis in BALB/c mice.
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
Asiaticoside improves diabetic nephropathy by reducing inflammation, oxidative stress, and fibrosis: An in vitro and in vivo study.
A proteomics-based study of the mechanism of oxymatrine to ameliorate hepatic fibrosis in mice.
Leptin promotes tendon stem/progenitor cell senescence through the AKT-mTOR signaling pathway.
CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis.
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
Injectable citrate-based polyurethane-urea as a tug-of-war-inspired bioactive self-expansive and planar-fixing screw augmented bone-tendon healing.
Targeted Therapy of Osteoarthritis via Intra-Articular Delivery of Lipid-Nanoparticle-Encapsulated Recombinant Human FGF18 mRNA.
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
Angiotensin II depends on hippo/YAP signaling to reprogram angiogenesis and promote liver fibrosis.
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling.
Fusion protein of FGF21 and elastin-like peptide improves wound healing in diabetic mice via inflammation modulation, collagen synthesis, and vascular network formation.
Targeting GPR39 in structure-based drug discovery reduces Ang II-induced hypertension.
Quercetin Alleviates Scleral Remodeling Through Inhibiting the PERK-EIF2α Axis in Experiment Myopia.
Dexamethasone: a cheap and convenient way to alleviate subsequent stenosis after thermal injury on ureter.
DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis.
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Transcriptomics of tissue exosomes to investigate miR-195-5p's amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study.
Exploring the role of iNOS in HFpEF-Related myocardial fibrosis: Involvement of PTEN-PI3K/AKT signaling pathway.
CD248 interacts with ECM to promote hypertrophic scar formation and development.
Deacetylation of HnRNP U mediated by sirtuin1 ameliorates aged rat with liver fibrosis via inhibiting p53-related senescence and NLRP3-related inflammation.
Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression.
Overexpression of STX11 alleviates pulmonary fibrosis by inhibiting fibroblast activation via the PI3K/AKT/mTOR pathway.
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways.
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Regulatory T cell-derived exosome mediated macrophages polarization for osteogenic differentiation in fracture repair.
Factors Affecting the Evaluation of Collagen Deposition and Fibrosis In Vitro.
Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis.
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition.
Effect of polydimethylsiloxane surface morphology on osteogenic differentiation of mesenchymal stem cells through SIRT1 signalling pathway.
METTL14 affects UVB-induced human dermal fibroblasts photoaging via miR-100-3p biogenesis in an m(6)A-dependent manner.
Kefir peptides mitigate bleomycin-induced pulmonary fibrosis in mice through modulating oxidative stress, inflammation and gut microbiota.
Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis.
Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration.
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
Describing the Cellular Impact of IQOS™ Smoke Extract and Vibration on Human Vocal Fold Fibroblasts.
DDX58 variant triggers IFN-β-induced autophagy in trabecular meshwork and influences intraocular pressure.
Chaperone-mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β-catenin pathway.
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.
miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation via targeting BAMBI.
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Induce Fetal Wound Healing Features Revealed by Single-Cell RNA Sequencing.
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis.
Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects.
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
OTUD1 promotes isoprenaline- and myocardial infarction-induced heart failure by targeting PDE5A in cardiomyocytes.
Characterization of Chitosan-Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application.
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Peptide-Based Hydrogel Scaffold Facilitates Articular Cartilage Damage Repair.
Astaxanthin attenuates cigarette smoke-induced small airway remodeling via the AKT1 signaling pathway.
Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon.
Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation.
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.
Tianhuang formula ameliorates liver fibrosis by inhibiting CCL2-CCR2 axis and MAPK/NF-κB signaling pathway.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Fibroblast-Specific Depletion of Human Antigen R Alleviates Myocardial Fibrosis Induced by Cardiac Stress.
In vitro modeling of recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-aminolevulinic acid photodynamic therapy efficacy.
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
Calcitriol ameliorates the progression of hepatic fibrosis through autophagy-related gene 16-like 1-mediated autophagy.
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Injectable, stable, and biodegradable hydrogel with platelet-rich plasma induced by l-serine and sodium alginate for effective treatment of intrauterine adhesions.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
Gasdermin D silencing alleviates airway inflammation and remodeling in an ovalbumin-induced asthmatic mouse model.
Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosis.
Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1(+) Th17 cells and fibroblasts.
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
The Development of a 3D PET Fibrous Scaffold Modified with an Umbilical Cord dECM for Liver Tissue Engineering.
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Sodium arsenite induces hepatic stellate cells activation by m(6)A modification of TGF-β1 during liver fibrosis.
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation.
CircFgfr2 promotes osteogenic differentiation of rat dental follicle cells by targeting the miR-133a-3p/DLX3 signaling pathway.
Alantolactone attenuates high-fat diet-induced inflammation and oxidative stress in non-alcoholic fatty liver disease.
C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis.
Carnosol prevents cardiac remodeling and ventricular arrhythmias in pressure overload-induced heart failure mice.
Alginate-containing 3D-printed hydrogel scaffolds incorporated with strontium promotes vascularization and bone regeneration.
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
Picroside II promotes HSC apoptosis and inhibits the cholestatic liver fibrosis in Mdr2(-/-) mice by polarizing M1 macrophages and balancing immune responses.
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Long Non-coding RNA ZFAS1 Regulates Fibrosis and Scortosis in the Cell Model of Diabetic Nephropathy Through miR-525-5p/SGK1 Axis.
Hierarchically Biomimetic Scaffolds with Anisotropic Micropores and Nanotopological Patterns to Promote Bone Regeneration via Geometric Modulation.
Lapagyl mitigates UV-induced inflammation and immunosuppression via Foxp3+ Tregs and CCL pathway: A single-cell transcriptomics study.
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Aggregation-Induced Emission CN-Based Nanoparticles to Alleviate Hypoxic Liver Fibrosis via Triggering HSC Ferroptosis and Enhancing Photodynamic Therapy.
Salvianolic acid B protects against UVB-induced skin aging via activation of NRF2.
Flexible Sono-Piezo Patch for Functional Sweat Gland Repair through Endogenous Microenvironmental Remodeling.
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
Comparative Analysis of Decellularization Methods for the Production of Decellularized Umbilical Cord Matrix.
CircSMAD3 represses SMAD3 phosphorylation and ameliorates cardiac remodeling by recruiting YBX1.
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Targeting of G protein-coupled receptor 39 alleviates angiotensin II-induced renal damage by reducing ribonucleotide reductase M2.
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
ROS-responsive core-shell nano-inhibitor impedes pyruvate metabolism for reinforced photodynamic therapy and interrupted pre-metastatic niche formation.
Cysteine and glycine-rich protein 2 retards platelet-derived growth factor-BB-evoked phenotypic transition of airway smooth muscle cells by decreasing YAP/TAZ activity.
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Inhibition of TGFβ1 activation prevents radiation-induced lung fibrosis.
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Hsa_circ_0081065 exacerbates IH-induced EndMT via regulating miR-665/HIF-1α signal axis and HIF-1α nuclear translocation.
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.
Rejuvenating Hyaline Cartilaginous Phenotype of Dedifferentiated Chondrocytes in Collagen II Scaffolds: A Mechanism Study Using Chondrocyte Membrane Nanoaggregates as Antagonists.
S100A8/A9 promotes endometrial fibrosis via regulating RAGE/JAK2/STAT3 signaling pathway.
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes.
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Oxidative modification of collagen by malondialdehyde in porcine skin.
Microplastics cause hepatotoxicity in diabetic mice by disrupting glucolipid metabolism via PP2A/AMPK/HNF4A and promoting fibrosis via the Wnt/β-catenin pathway.
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
An Injectable Composite Hydrogel of Verteporfin-Bonded Carboxymethyl Chitosan and Oxidized Sodium Alginate Facilitates Scarless Full-Thickness Skin Regeneration.
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
In Vitro and In Vivo Bone-Forming Effect of a Low-Molecular-Weight Collagen Peptide.
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway.
[Ubiquitin-specific protease 42 regulates osteogenic differentiation of human adipose-derived stem cells].
Pharmacological inhibition of ICOS attenuates the protective effect of exercise on cardiac fibrosis induced by isoproterenol.
M(3) subtype of muscarinic acetylcholine receptor inhibits cardiac fibrosis via targeting microRNA-29b/beta-site app cleaving enzyme 1 axis.
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
PUD@HA/PEEK Scaffold Induces Subchondral Bone Regeneration to Repair Osteochondral Defect in Rabbits.
Buyang Huanwu Decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway.
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
[(18)F]AlF-CBP imaging of type I collagen for non-invasive monitoring of pulmonary fibrosis in preclinical models.
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
α-Mangostin Attenuates Blood Pressure and Reverses Vascular Remodeling by Balancing ACE/AT1R and ACE2/Ang-(1-7)/MasR Axes in Ang II-Infused Hypertensive Mice.
Macrophage polarization and macrophage-related factor expression in hypertrophy of the ligamentum flavum.
Exploring the anti‑oxidative mechanisms of Rhodiola rosea in ameliorating myocardial fibrosis through network pharmacology and in vitro experiments.
Dihydrolipoamide S-acetyltransferase activation alleviates diabetic kidney disease via AMPK-autophagy axis and mitochondrial protection.
Heat shock protein 27 downregulation attenuates isoprenaline-induced myocardial fibrosis and diastolic dysfunction by modulating the endothelial-mesenchymal transition.
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
An anti-RAGE chimeric antibody alleviates CCl(4)-induced liver fibrosis via RAGE/NF-kB pathway in mice.
Diagnostic significance of LncRNA MIAT in periodontitis and the molecular mechanisms influencing periodontal ligament fibroblasts via the miR-204-5p/DKK1 axis.
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
The JNK-associated leucine zipper protein exerts a protective effect on renal parenchymal injury by limiting the inflammatory secretome in tubular cells.
Genetic Characteristics of the Rat Fibroblast Cell Line Rat-1.
LCCP exposure leads to skin cell senescence damage by triggering oxidative stress mediated by mitochondrial Ca(2+) overload.
The bach1/G9a/Slc7a11 axis epigenetically promotes renal fibrosis by mediated ferroptosis.
Cell membrane-camouflaged nanoparticles activate fibroblast-myofibroblast transition to promote skin wound healing.
Baicalin improves isoproterenol-induced cardiac remodeling by regulating the Nrf2-dependent signaling pathway.
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Cerium Oxide Nanoparticles-Reinforced GelMA Hydrogel Loading Bone Marrow Stem Cells with Osteogenic and Inflammatory Regulatory Capacity for Bone Defect Repair.
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
Serum deprivation protein response intervenes in the proliferation, motility, and extracellular matrix production in keloid fibroblasts by blocking the amplification of TGF-β1/SMAD signal cascade via ERK1/2.
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1.
A Superparamagnetic Composite Hydrogel Scaffold as In Vivo Dynamic Monitorable Theranostic Platform for Osteoarthritis Regeneration.
Macromolecular Crowding Enhances Matrix Protein Deposition in Tissue-Engineered Vascular Grafts.
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis.
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Injectable, degradable, and mechanically adaptive hydrogel induced by L-serine and allyl-functionalized chitosan with platelet-rich plasma for treating intrauterine adhesions.
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3.
Gas6-Axl signal promotes indoor VOCs exposure-induced pulmonary fibrosis via pulmonary microvascular endothelial cells-fibroblasts cross-talk.
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Titanium nanoparticles released from orthopedic implants induce muscle fibrosis via activation of SNAI2.
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Association of IL-9 Cytokines with Hepatic Injury in Echinococcus granulosus Infection.
METTL3 Promotes Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration by Regulating TLR2 m6A Methylation and Gut Microbiota.
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Targeting S100A9 Prevents β-Adrenergic Activation-Induced Cardiac Injury.
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress.
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
Histone methyltransferase Suv39h1 regulates hepatic stellate cell activation and is targetable in liver fibrosis.
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling.
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization.
ED-71 ameliorates bone regeneration in type 2 diabetes by reducing ferroptosis in osteoblasts via the HIF1α pathway.
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Photocurable 3D-printed PMBG/TCP biphasic scaffold mimicking vasculature for bone regeneration.
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail Signaling.
Hyaluronic acid hydrogels support to generate integrated bone formation through endochondral ossification in vivo using mesenchymal stem cells.
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment.
Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats.
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease.
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis.
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer.
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Association of FOXO3A with right ventricular myocardial fibrosis and its detection by speckle-tracking echocardiography in pulmonary hypertension.
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Axitinib attenuates the progression of liver fibrosis by restoring mitochondrial function.
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Inhibition of ACSL4 ameliorates tubular ferroptotic cell death and protects against fibrotic kidney disease.
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia.
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Multi-targeting liposomal codelivery of cisplatin and rapamycin inhibits pancreatic cancer growth and metastasis through stromal modulation.
Construction of a Collagen-like Protein Based on Elastin-like Polypeptide Fusion and Evaluation of Its Performance in Promoting Wound Healing.
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts.
Near-Infrared Light-Controlled MicroRNA-21-Loaded Upconversion Nanoparticles to Promote Bone Formation in the Midpalatal Suture.
Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis.
Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathway.
Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization.
MYCT1 attenuates renal fibrosis and tubular injury in diabetic kidney disease.
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
Robust Osteoconductive β-Tricalcium Phosphate/L-poly(lactic acid) Membrane via Orientation-Strengthening Technology.
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathway.
Increased Expression of Adipokines in Patients With Frozen Shoulder.
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis.
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Myeloid-specific deletion of Capns1 attenuates myocardial infarction injury via restoring mitochondrial function and inhibiting inflammasome activation.
Inhibition of annexin A7 suppresses senescence-associated heterochromatin foci formation and senescence through the AMPK/mTOR pathway in human dermal fibroblasts.
Farnesoid X receptor activation is required for the anti-inflammatory and anti-oxidative stress effects of Alisol B 23-acetate in carbon tetrachloride-induced liver fibrosis in mice.
Photocurable 3D-Printed PMBG/TCP Scaffold Coordinated with PTH (1-34) Bidirectionally Regulates Bone Homeostasis to Accelerate Bone Regeneration.
Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway.
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling.
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes.
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53.
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Structural analysis and attenuates hyperuricemic nephropathy of dextran from the Imperata cylindrica Beauv. var. major (Nees) C. E. Hubb.
Single-nucleus RNA sequencing reveals heterogenous microenvironments and specific drug response between cervical squamous cell carcinoma and adenocarcinoma.
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Macrophage RAGE deficiency prevents myocardial fibrosis by repressing autophagy-mediated macrophage alternative activation.
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Injectable kaempferol-loaded fibrin glue regulates the metabolic balance and inhibits inflammation in intervertebral disc degeneration.
Hyaluronic acid-mediated collagen intrafibrillar mineralization and enhancement of dentin remineralization.
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis.
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Pilose antler extract restores type I and III collagen to accelerate wound healing.
GATA6 triggers fibroblast activation and tracheal fibrosis through the Wnt/β-catenin pathway.
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Oleuropein-Rich Gellan Gum/Alginate Films as Innovative Treatments against Photo-Induced Skin Aging.
Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α-sXBP1-GATA4 pathway.
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
The role of interleukin 36γ in the epithelial-mesenchymal transition process of chronic rhinosinusitis: A pilot study.
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway.
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
m(6)A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis.
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling.
Herbal formula Jiawei Xiaochengqi decoction prevents postoperative abdominal adhesion in a rat model through inhibition of CXCL2-CXCR2 pathway.
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
PCSK9 Inhibition Regulates Infarction-Induced Cardiac Myofibroblast Transdifferentiation via Notch1 Signaling.
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis.
Cartilage-like protein hydrogels engineered via entanglement.
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Hsa-miR-379 down-regulates Rac1/MLK3/JNK/AP-1/Collagen I cascade reaction by targeting connective tissue growth factor in human alveolar basal epithelial A549 cells.
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells.
Wound Gel with Antimicrobial Effects Based on Polyvinyl Alcohol and Functional Aryloxycyclotriphosphazene.
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis.
RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse.
Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca(2+)/ROS pathway in platelets to ameliorate inflammatory coagulopathy.
A seminal perspective on the role of chondroitin sulfate in biomineralization.
Sparganii Rhizoma alleviates pulmonary fibrosis by inhibiting fibroblasts differentiation and epithelial-mesenchymal transition mediated by TGF-β1/ Smad2/3 pathway.
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse.
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1.
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Inhaled Lipid Nanoparticles Alleviate Established Pulmonary Fibrosis.
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells.
Metformin attenuates chronic lung allograft dysfunction: evidence in rat models.
CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function.
Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products.
Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice.
Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH.
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Crystalline silica-induced macrophage pyroptosis interacting with mitophagy contributes to pulmonary fibrosis via modulating mitochondria homeostasis.
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Gypenosides suppress fibrosis of the renal NRK-49F cells by targeting miR-378a-5p through the PI3K/AKT signaling pathway.
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Instantaneous self-healing and strongly adhesive self-adaptive hyaluronic acid-based hydrogel for controlled drug release to promote tendon wound healing.
Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
IKKα aggravates renal fibrogenesis by positively regulating the Wnt/β-catenin pathway.
Differentiation ability of Gli1(+) cells during orthodontic tooth movement.
The combination of exercise and metformin inhibits TGF-β1/Smad pathway to attenuate myocardial fibrosis in db/db mice by reducing NF-κB-mediated inflammatory response.
The aggravate role of exosomal circRNA11:120406118|12040782 on macrophage pyroptosis through miR-30b-5p/NLRP3 axis in silica-induced lung fibrosis.
Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38.
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
7,8-Dihydroxyflavone alleviates cardiac fibrosis by restoring circadian signals via downregulating Bmal1/Akt pathway.
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Promotion of the genipin crosslinked chitosan-fiber hydrogel loaded with sustained release of clemastine fumarate in diabetic wound repair.
Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation.
Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease.
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy.
Macrophage-derived exosomal lncRNA MSTRG.91634.7 inhibits fibroblasts activation by targeting PINK1 in silica-induced lung fibrosis.
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Toll-like receptor-2 in cardiomyocytes and macrophages mediates isoproterenol-induced cardiac inflammation and remodeling.
Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Hyperlipidemia impacts osteogenesis via lipophagy.
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice.
Loss of Protein Kinase D2 Activity Protects Against Bleomycin-Induced Dermal Fibrosis in Mice.
Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia-reperfusion injury.
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
Albumin-Based Silibinin Nanocrystals Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy.
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Deciphering the underlying wound healing mechanisms of Streptocaulon juventas (Lour.) Merr. by integrating network pharmacology, transcriptomics, and experimental validation.
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Nanomechanical-based classification of prostate tumor using atomic force microscopy.
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Design of a Haversian system-like gradient porous scaffold based on triply periodic minimal surfaces for promoting bone regeneration.
LPS-induced macrophage exosomes promote the activation of hepatic stellate cells and the intervention study of total astragalus saponins combined with glycyrrhizic acid.
Inhaled pulmonary surfactant biomimetic liposomes for reversing idiopathic pulmonary fibrosis through synergistic therapeutic strategy.
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
Anthelmintic nitazoxanide protects against experimental pulmonary fibrosis.
Expression and function of CCN2-derived circRNAs in chondrocytes.
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
BMAL1 inhibits renal fibrosis and renal interstitial inflammation by targeting the ERK1/2/ELK-1/Egr-1 axis.
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
TRIOBP modulates β-catenin signaling by regulation of miR-29b in idiopathic pulmonary fibrosis.
Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cross-Linked With Lysine Amino Acid for Skin Augmentation and Rejuvenation.
The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
The application of a novel platform of multiparametric magnetic resonance imaging in a bioenvironmental toxic carbon tetrachloride-induced mouse model of liver fibrosis.
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
AP-1 signaling modulates cardiac fibroblast stress responses.
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Sustained release of magnesium and zinc ions synergistically accelerates wound healing.
TSLP/TSLPR promotes renal fibrosis by activating STAT3 in renal fibroblasts.
Tough Gelatin Hydrogel for Tissue Engineering.
Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
Transcriptomics Reveals Molecular Features of the Bilateral Pelvic Nerve Injury Rat Model of Detrusor Underactivity.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism.
Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration.
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Relaxin-2 Prevents Erectile Dysfunction by Cavernous Nerve, Endothelial and Histopathological Protection Effects in Rats with Bilateral Cavernous Nerve Injury.
Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti-Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis.
Deficiency of HtrA3 Attenuates Bleomycin-Induced Pulmonary Fibrosis Via TGF-β1/Smad Signaling Pathway.
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
PDGFBB improved the biological function of menstrual blood-derived stromal cells and the anti-fibrotic properties of exosomes.
Stiffness-dependent dynamic effect of inflammation on keratocyte phenotype and differentiation.
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
GL-V9 ameliorates liver fibrosis by inhibiting TGF-β/smad pathway.
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling.
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
CIDEC: A Potential Factor in Diabetic Vascular Inflammation.
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Wen-Yu-Jin against Pulmonary Fibrosis in a Mouse Model.
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells.
Shenxian-Shengmai Oral Liquid Evoke Autophagy of Fibroblast to Attenuate Sinoatrial Node Fibrosis in Sick Sinus Syndrome Mice via the AKT/mTOR Pathway.
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats.
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer.
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Effect of Tensile Frequency on the Osteogenic Differentiation of Periodontal Ligament Stem Cells.
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats.
Compared with High-intensity Interval Exercise, Moderate Intensity Constant Load Exercise is more effective in curbing the Growth and Metastasis of Lung Cancer.
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a.
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis.
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα.
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Nanosilicate-Reinforced Silk Fibroin Hydrogel for Endogenous Regeneration of Both Cartilage and Subchondral Bone.
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice.
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Grp94 Inhibitor HCP1 Inhibits Human Dermal Fibroblast Senescence.
EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy.
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Green Tea Polyphenols Prevent Early Vascular Aging Induced by High-Fat Diet via Promoting Autophagy in Young Adult Rats.
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner.
Curcumin analog JM-2 alleviates diabetic cardiomyopathy inflammation and remodeling by inhibiting the NF-κB pathway.
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
FGFR2 Mutation p.Cys342Arg Enhances Mitochondrial Metabolism-Mediated Osteogenesis via FGF/FGFR-AMPK-Erk1/2 Axis in Crouzon Syndrome.
HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway.
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Synergistic anti-inflammatory effect of gut microbiota and lithocholic acid on liver fibrosis.
Critical role of PAFR/YAP1 positive feedback loop in cardiac fibrosis.
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Pathological collagen targeting and penetrating liposomes for idiopathic pulmonary fibrosis therapy.
Antifibrotic pyridine-containing monoterpene alkaloids from Caryopteris glutinosa.
Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosis.
The Impact of Sleep Disturbance on Gut Microbiota, Atrial Substrate, and Atrial Fibrillation Inducibility in Mice: A Multi-Omics Analysis.
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway.
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.
Interfering Hsa_circRNA_0060640 Suppresses TGF-β2-Induced Proliferation, Motility and EMT in Human Lens Epithelium Cells by Targeting miR-214-3p and Collagen Type I alpha2 Chain.
Cryo-injury procedure-induced cardiac regeneration shows unique gene expression profiles in the newt Pleurodeles waltl.
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Improved epicardial cardiac fibroblast generation from iPSCs.
Rab31 promotes activation of hepatic stellate cells by accelerating TGF-β receptor II complex endocytosis.
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling.
Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox.
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Pyrroloquinoline quinone ameliorates diabetic cardiomyopathy by inhibiting the pyroptosis signaling pathway in C57BL/6 mice and AC16 cells.
Citri Reticulatae Pericarpium alleviates postmyocardial infarction heart failure by upregulating PPARγ expression.
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells.
Histamine Deficiency Promotes Myofibroblasts Transformation from HDC-Expressing CD11b(+) Myeloid Cells in Injured Hearts Post Myocardial Infarction.
Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model.
Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis.
Beta-hydroxybutyrate dampens adipose progenitors' profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms.
Integrated multicomponent analysis based on UHPLC-Q-Exactive Orbitrap-MS and network pharmacology to elucidate the potential mechanism of Baoyuan decoction against idiopathic pulmonary fibrosis.
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice.
Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis.
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
TGFβ1-transfected tendon stem cells promote tendon fibrosis.
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Morphological changes of macrophages and their potential contribution to tendon healing.
VX-765 ameliorates renal injury and fibrosis in diabetes by regulating caspase-1-mediated pyroptosis and inflammation.
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.
A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer.
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Qingda granule prevents obesity-induced hypertension and cardiac dysfunction by inhibiting adverse Akt signaling activation.
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway.
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells.
An improved explants culture method: Sustainable isolation of keloid fibroblasts with primary characteristics.
PVA/pectin composite hydrogels inducing osteogenesis for bone regeneration.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Bioprinted living tissue constructs with layer-specific, growth factor-loaded microspheres for improved enthesis healing of a rotator cuff.
Freeze-casting osteochondral scaffolds: The presence of a nutrient-permeable film between the bone and cartilage defect reduces cartilage regeneration.
IL-8 exacerbates CCl(4)-induced liver fibrosis in human IL-8-expressing mice via the PI3K/Akt/HIF-1α pathway.
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
β3 adrenoceptor agonist mirabegron protects against right ventricular remodeling and drives Drp1 inhibition.
Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice.
Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats.
Hydroxyapatite-Tethered Peptide Hydrogel Promotes Osteogenesis.
The m(6)A methyltransferase Mettl3 deficiency attenuates hepatic stellate cell activation and liver fibrosis.
Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3.
TIPARP is involved in the regulation of intraocular pressure.
Non-cell-autonomous activation of hedgehog signaling contributes to disease progression in a mouse model of renal cystic ciliopathy.
ER-phagy Is Involved in the Degradation of Collagen I by IL-1β in Human Amnion in Parturition.
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells.
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Piezo1 act as a potential oncogene in pancreatic cancer progression.
Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells.
Exercise-derived peptide protects against pathological cardiac remodeling.
Thin film nanoarchitectonics of layer-by-layer assembly with reduced graphene oxide on intraocular lens for photothermal therapy of posterior capsular opacification.
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
AGEs-RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure.
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
Targeted inhibition of TGF-β type I receptor by AZ12601011 protects against kidney fibrosis.
Semaphorin 3A attenuates the hypoxia suppression of osteogenesis in periodontal ligament stem cells.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Suppression of LMCD1 ameliorates renal fibrosis by blocking the activation of ERK pathway.
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
MCC950 ameliorates ventricular arrhythmia vulnerability induced by heart failure.
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.
PEDF is an antifibrosis factor that inhibits the activation of fibroblasts in a bleomycin-induced pulmonary fibrosis rat model.
Exosomes derived from hypoxia preconditioned mesenchymal stem cells laden in a silk hydrogel promote cartilage regeneration via the miR-205-5p/PTEN/AKT pathway.
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Epigenetic Repression of Chloride Channel Accessory 2 Transcription in Cardiac Fibroblast: Implication in Cardiac Fibrosis.
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
In Vitro Methods to Evaluate the Effects of Mesenchymal Stem Cells on TGF-β1-Induced Pulmonary Fibrosis.
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.
NEDD4L-induced β-catenin ubiquitination suppresses the formation and progression of interstitial pulmonary fibrosis via inhibiting the CTHRC1/HIF-1α axis.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Pressing Intervention Promotes the Skeletal Muscle Repair of Traumatic Myofascial Trigger Points in Rats.
Substance P-induced RAD16-I scaffold mediated hUCMSCs stereo-culture triggers production of mineralized nodules and collagen-like fibers by promoting osteogenic genes expression.
Deletion of p16 accelerates fracture healing in geriatric mice.
Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence.
Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway.
Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway.
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury.
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
Exercise training ameliorates early diabetic kidney injury by regulating the H(2) S/SIRT1/p53 pathway.
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
The different functions of short and long thymic stromal lymphopoietin isoforms in autophagy-mediated asthmatic airway inflammation and remodeling.
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification.
Splicing factor SRSF6 mediates pleural fibrosis.
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury.
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway.
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency.
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.
HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.
Role and mechanism of TXNIP in ageing-related renal fibrosis.
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Comparison of chondrogenesis-related biological behaviors between human urine-derived stem cells and human bone marrow mesenchymal stem cells from the same individual.
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury.
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
Bortezomib limits renal allograft interstitial fibrosis by inhibiting NF-κB/TNF-α/Akt/mTOR/P70S6K/Smurf2 pathway via IκBα protein stabilization.
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
The application of human periodontal ligament stem cells and biomimetic silk scaffold for in situ tendon regeneration.
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity.
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.
Enzymatically crosslinked silk-nanosilicate reinforced hydrogel with dual-lineage bioactivity for osteochondral tissue engineering.
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity.
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Adenosine A3 receptor activated in H(2)O(2) oxidative stress of primary open-angle glaucoma.
Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice.
Overexpression of Fgf8 in the epidermis inhibits hair follicle development.
Endogenous production of n-3 polyunsaturated fatty acids protects mice from carbon tetrachloride-induced liver fibrosis by regulating mTOR and Bcl-2/Bax signalling pathways.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-κB Signaling Pathway.
Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice.
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
Inhibition of miR-182-5p attenuates pulmonary fibrosis via TGF-β/Smad pathway.
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Melatonin up-regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT(2) -inactivated NF-κB pathway.
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Comprehensive circRNA expression profile and construction of circRNA-related ceRNA network in cardiac fibrosis.
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis.
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing.
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p.
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway.
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
Synthesis and discovery of new compounds bearing coumarin scaffold for the treatment of pulmonary fibrosis.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
N(6)-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon black particles in rats.
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage.
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis.
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit.
Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
A novel knitted scaffold made of microfiber/nanofiber core-sheath yarns for tendon tissue engineering.
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury.
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway.
A Biomimetic Model for Mineralization of Type-I Collagen Fibrils.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Presence and function of stress granules in atrial fibrillation.
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
Rubidium-Containing Calcium Alginate Hydrogel for Antibacterial and Diabetic Skin Wound Healing Applications.
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
The effect of topical ramipril and losartan cream in inhibiting scar formation.
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
ClC-3 chloride channels are involved in estradiol regulation of bone formation by MC3T3-E1 osteoblasts.
Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro.
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis.
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Role of synovium-derived fibrous cartilage in temporomandibular joint synovial chondromatosis.
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair.
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
A Novel Tissue-Engineered Corneal Stromal Equivalent Based on Amniotic Membrane and Keratocytes.
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes.
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
IMM-H007 improves heart function via reducing cardiac fibrosis.
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion.
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation.
Downregulation of S100A4 Alleviates Cardiac Fibrosis via Wnt/β -Catenin Pathway in Mice.
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
TGF-β1/Smad3 signaling promotes collagen synthesis in pulmonary artery smooth muscle by down-regulating miR-29b.
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure.
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Emission of sulfur dioxide from polyurethane foam and respiratory health effects.
Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects.
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1.
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
COL1A2 is a Novel Biomarker to Improve Clinical Prediction in Human Gastric Cancer: Integrating Bioinformatics and Meta-Analysis.
Losartan loaded liposomes improve the antitumor efficacy of liposomal paclitaxel modified with pH sensitive peptides by inhibition of collagen in breast cancer.
Regulation of pancreatic stellate cell activation by Notch3.
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas After Chronic Alcohol Exposure.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Effect of Polyhydroxybutyrate/Chitosan/Bioglass nanofiber scaffold on proliferation and differentiation of stem cells from human exfoliated deciduous teeth into odontoblast-like cells.
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
The Protective Effect of Cordycepin On Alcohol-Induced Osteonecrosis of the Femoral Head.
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction.
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Cadherin-11 modulates cell morphology and collagen synthesis in periodontal ligament cells under mechanical stress.
Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction.
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
SC79-loaded ZSM-5/chitosan porous scaffolds with enhanced stem cell osteogenic differentiation and bone regeneration.
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture.
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Autophagic Degradation of Collagen 1A1 by Cortisol in Human Amnion Fibroblasts.
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model.
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer.
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Store-Operated Ca(2+) Entry (SOCE) contributes to angiotensin II-induced cardiac fibrosis in cardiac fibroblasts.
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
miR-26a suppresses EMT by disrupting the Lin28B/let-7d axis: potential cross-talks among miRNAs in IPF.
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
A dual strategy to improve the penetration and treatment of breast cancer by combining shrinking nanoparticles with collagen depletion by losartan.
An Ultra-thin Amniotic Membrane as Carrier in Corneal Epithelium Tissue-Engineering.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis.
Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
High Tumor Penetration of Paclitaxel Loaded pH Sensitive Cleavable Liposomes by Depletion of Tumor Collagen I in Breast Cancer.
Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice.
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Surface chemistry modulates osteoblasts sensitivity to low fluid shear stress.
Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells.
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism.
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
Molecular events in matrix protein metabolism in the aging kidney.
Chen YJ, Chen LY, Pham NT, Vega JLD, Fulgheri F, Wang CC, Manca ML, Lee CJ
International journal of medical sciences 2026;23(4):1491-1508
International journal of medical sciences 2026;23(4):1491-1508
PTPN1 Regulation via YBX1-PTBP1 Interaction Promotes Fibroblast Activation and Fibrotic Remodeling in the Lung.
Liu H, Xia C, Zhang Y, Gan Y, Cheng L, Wang X, Chang A, Zhao W, Li B, Wang Y, Li Y, Rosas I, Yang J, Yu G, Wang L
International journal of biological sciences 2026;22(5):2233-2246
International journal of biological sciences 2026;22(5):2233-2246
Intracavernous Injection of Mechanically Extracted Stromal Vascular Fragments Suppresses Endothelial-Mesenchymal Transformation to Mitigate Erectile Dysfunction in Hypertensive Rats.
Shao C, Sun Y, Zhao J, Ju C, Yang T, Liu J, Zhou L, Jia R, Zhao F
Stem cells international 2026;2026:3343152
Stem cells international 2026;2026:3343152
Imperatorin Alleviates Intestinal Fibrosis by Suppressing AIM2-mediated GSDMD Pyroptosis in Macrophages.
Li S, Zhu F, Xie Y, Ben T, Liu K, Lin X, Zhou Q, Zhang Y, Zhang X, Chen Y, Ren Y, Wang X, Zhi F, Tan G
Cellular and molecular gastroenterology and hepatology 2026;20(1):101625
Cellular and molecular gastroenterology and hepatology 2026;20(1):101625
Berberine Ameliorates Diabetic Kidney Disease by Modulating Macrophage Polarization via Inhibiting IL-17A Signaling.
Fan J, Liu Y, Zheng C, Liu J, Liu W, Geng R, Zhao A, Wang Y, Wang R, Qi Z
Journal of inflammation research 2026;19:580534
Journal of inflammation research 2026;19:580534
Functionalized magnetic hydrogel encapsulation of human dental follicle stem cells under a static magnetic field enhances multi-site bone regeneration.
Deng P, Zheng M, Du B, Liu C, Cheng R, Liu C, Wang F, Dong H, Shan Y, Xu Y
Regenerative biomaterials 2026;13:rbag023
Regenerative biomaterials 2026;13:rbag023
Magnesium-doped bioactive glass enhances bone regeneration by reversing replicative senescence of human dental pulp stem cells in bone defect therapy.
Yan X, Li X, Zhang Q, He X, Chen Q, Mai S
Regenerative biomaterials 2026;13:rbaf105
Regenerative biomaterials 2026;13:rbaf105
SIRT3-mediated deacetylation of FoxM1 prevents pulmonary fibrosis via modulating the activation of pulmonary fibroblasts.
Dong J, Wang L, Wei A, Lin J, Xuan Y, Jiao Z, Bai Y, Shi X, Zhang Z, Sun W, Wang T, Chen X
Redox biology 2026 May;92:104108
Redox biology 2026 May;92:104108
Elevated lactate production exacerbates PM2.5-induced pulmonary fibrosis by stabilizing TGF-β1.
Liu Z, Liu W, Wei H, Ping Y, Yu Z, Dong Z, Ren J, Zhang S, Liu S
Journal of advanced research 2026 May;83:299-314
Journal of advanced research 2026 May;83:299-314
Propofol Exerted an Anti-Asthmatic Effect by Attenuating Extracellular Matrix Deposition and Viability of Airway Smooth Muscle Cells.
Chen Z, Jiang Y, Zhang H, An X, Zhang Y, Wei L
Immunological investigations 2026 May;55(4):734-749
Immunological investigations 2026 May;55(4):734-749
Pharmacodynamic evaluation and mechanism study of cord blood nucleated cell extract in the treatment of rheumatoid arthritis.
Guo R, Yang J, Zhang H, Zhang Y, Hou S, Zhang L, Han J, Yang W, Liu N, Qiu L
Clinical rheumatology 2026 May;45(5):2615-2626
Clinical rheumatology 2026 May;45(5):2615-2626
Endothelial Hippo pathway regulates the neutrophil niche and lung fibrosis.
Wu C, Chen X, Zhou J, Wang H, Huang X, Tang X, Cao Z, Ding BS
Pharmacological research 2026 May;227:108169
Pharmacological research 2026 May;227:108169
Osteoblast-derived osteomodulin restrains osteoclastogenesis via ITGB8/RRM2-mediated reduction of mitochondrial respiration and mitochondrial ATP production.
Jiang X, Chen H, Hou W, Dai C, Zhang R, Chen E, Zhang J, Wu W, Xu J, Chen M, Liu L, Tan X, Ji X, Wu X, Wang K, Yu C, Yu X, Li W, Zhang W
Experimental & molecular medicine 2026 Mar;58(3):879-897
Experimental & molecular medicine 2026 Mar;58(3):879-897
IL-11 Drives Dermal Fibroblast Activation in Mechanical Stretch-Mediated Skin Expansion.
Liu Y, Khoong YM, Xia W, Xu R, Widjaja AA, Liang H, Luo S, Yang E, Huang X, Zan T
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
The Journal of investigative dermatology 2026 Mar;146(3):743-757.e9
Cascade Therapy of Periodontitis via Sequential Release of Ribosome-Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF-Based System.
Chen Y, Xu Z, Xue Y, Liu S, Zhang X, Guo J, Yao M, Liu Y, Lu X, Qian J, Ma Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e21553
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(18):e21553
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5-Dependent RNA Demethylation.
Qin T, Pan A, Miao Z, Zhao Y, Mo X, Sun H, Fan C, Guo J, Wu B, Shen W, Zheng Q, Lu J, Jiang X, Yin Z, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(17):e08376
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(17):e08376
Identification and Validation of MTFP1 as a Mitochondrial Target Restoring Dynamics and ECM Remodeling in Acute Myocardial Infarction.
Hu X, Bao H, Huang Y, Cao Z, Yang W, Huang C, Chen X, Chen Y, Chen B, Xia G, Yang X, Huang R, Chen Z
Current issues in molecular biology 2026 Mar 9;48(3)
Current issues in molecular biology 2026 Mar 9;48(3)
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
Yang K, Li J, Wang L, Yu H, Liu X, Gao Z, Wang Z, Zhang L, Yang H
BMC complementary medicine and therapies 2026 Mar 9;26(1)
BMC complementary medicine and therapies 2026 Mar 9;26(1)
TWIST1-Mediated Induction of AEBP1 in Fibroblast-Like Synoviocytes Activates Transforming Growth Factor β Signaling to Drive Angiogenesis and Promote Rheumatoid Arthritis.
Li Z, Cai M, Huang W, Wen X, Li Y, Sun J, Zhu C, Yang C, Chen Z
Arthritis & rheumatology (Hoboken, N.J.) 2026 Mar 5;
Arthritis & rheumatology (Hoboken, N.J.) 2026 Mar 5;
Development of Intervertebral Disc Organoids through Directed Differentiation of Mesenchymal Stem Cells and Hierarchical 3D Printing.
Wu D, Zhu D, Zhou X, Li G, Zhang X, Ma L, Liang H, Tong B, Lei J, Wang H, Ke W, Feng X, Wang K, Tan L, Shi Y, Yang C, Wang B
ACS nano 2026 Mar 31;20(12):9619-9637
ACS nano 2026 Mar 31;20(12):9619-9637
A Biocompatible CMCHMA/F127DA Hydrogel with ROS-Scavenging Activity Prevents Postoperative Peritoneal Adhesions.
Xia Z, Wang W, He L, Xia Z, Li J, Dong Q
ACS omega 2026 Mar 31;11(12):19192-19200
ACS omega 2026 Mar 31;11(12):19192-19200
Time-Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism.
Xia X, Kong C, Zhao X, Shi N, Jiang J, Li P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e15505
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar 31;:e15505
Sexual dimorphism in keratoconus: transcriptomic and hormonal mechanisms underlying stromal remodelling.
Sun Y, Li Q, Wu X, Yu X, Wang R, Sun B, Wang K, Yu Y, Chen S, Jiang D, Chen W
Eye and vision (London, England) 2026 Mar 3;13(1)
Eye and vision (London, England) 2026 Mar 3;13(1)
Hydrogen sulfide ameliorates oxalate crystal-related renal injury via inhibiting the activation of NOD-like receptor thermal protein domain associated protein 3 inflammasome in mice.
Shi Y, Chen L, Li M, Wang J, Yin P, Zhou X, Cong Q, Song K
Urolithiasis 2026 Mar 24;54(1)
Urolithiasis 2026 Mar 24;54(1)
High-Intensity Interval Training Outperforms Moderate-Intensity Exercise in Hyperlipidemic ApoE⁻/⁻ Mice: A Molecular and Histological Comparison.
Qian C, Pei Z, Yang Z, Sun M, Zhang Y, Liu H, Sun Y
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
Frontiers in bioscience (Landmark edition) 2026 Mar 20;31(3):47751
Design, synthesis, and anti-liver fibrosis activity of novel non-steroidal vitamin D receptor agonists based on phenyl-indole scaffold.
Tong Y, Cheng N, Guan C, Wu Y, Gao Y, Liu S, Wang C, Zhang C
European journal of medicinal chemistry 2026 Mar 15;306:118592
European journal of medicinal chemistry 2026 Mar 15;306:118592
Microfluidic Encapsulation of Genetically Engineered Bone-marrow-derived Mesenchymal Stem Cells for Bone Defect Healing.
Ding W, Luo Z, Che J, Gan J, Zhao Y
Advanced healthcare materials 2026 Mar 15;:e05260
Advanced healthcare materials 2026 Mar 15;:e05260
Lipotoxic hepatocyte-derived UBQLN1-enriched small extracellular vesicles activate hepatic stellate cells to promote hepatic fibrosis.
Yang F, Chen Y, Wang Y, Zheng G, Abouelnazar F, Fan L, Wang Y, Yan Y
Autophagy 2026 Mar 13;:1-23
Autophagy 2026 Mar 13;:1-23
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Xu Y, Zhang Y, Sun Z, Gong J, Shen Q, Meng H, Liu X, Chen J, Hao Y, Xu Z, Ma K, Ma L, Guo K, Pan X, Fu X, Zhang C
Materials today. Bio 2026 Jun;38:103117
Materials today. Bio 2026 Jun;38:103117
Helicobacter pylori-secreted outer membrane vesicles induce bone loss and accelerate osteoporosis pathogenesis in mice by regulating gut microbiota and autophagy.
Zhao J, Liu J, Huang S, Ye S, Zhao S
Microbiological research 2026 Jun;307:128485
Microbiological research 2026 Jun;307:128485
Prostaglandin F2α impairs skin regeneration via FP receptor-mediated oxidative stress overriding autophagic protection in fibroblasts.
Wen Z, Guo Y, Bai R, Liu W, Liang B, Dong C, Zhang Y, Song Y, Wang T, Wang Z, Du J, Ma X, Ding J, Yu Z
Pathology, research and practice 2026 Jun;282:156467
Pathology, research and practice 2026 Jun;282:156467
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Wang D, Zhou Z, Zhao Z, Liu M, Li Y, Mu L, Zhou H, Li X, Zhang F, Tian S, Zhou X, Shi Y
Free radical biology & medicine 2026 Jun;249:246-259
Free radical biology & medicine 2026 Jun;249:246-259
Hyperoside stabilizes ACAT1 to promote fatty acid oxidation and attenuate kidney fibrosis via the L-carnitine-SIRT3 axis.
Shan C, Szili-Torok T, Yue G, Zhang L, Morioka T, Ochi A, Xu J, Liu Z, Yu J, Huang L, Zhou X, Li F, Xu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158080
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158080
Adhesion molecule with Ig-like domain 1 regulates stability of carotid plaque via TGFβ/Smad signaling pathway by interaction with TGFRII.
Hu X, Li X, Chen J, Li Y, Zhao Z, Yin X, Duan S, Wang B
Cellular signalling 2026 Jun;142:112412
Cellular signalling 2026 Jun;142:112412
Exosomal miRNA let-7i-5p alleviates asthma triggered by RSV-induced exosomes by regulating dendritic cell autophagy via the MITF/DAP1/P70S6K pathway.
Liu J, Yao B, Wang S, Deng Y, Xie J, Jiao L, Hu Y, Zhou Z, Ding Y, Luo Y, Wang M
Cellular signalling 2026 Jul;143:112491
Cellular signalling 2026 Jul;143:112491
CACNB2 overexpression suppresses atrial fibroblast activation and atrial fibrosis to mitigate atrial fibrillation.
Zhang D, Li Z, Li N, Zhang H
Cellular signalling 2026 Jul;143:112448
Cellular signalling 2026 Jul;143:112448
Asymmetrical paravertebral muscles fibrosis causes progression of adolescent idiopathic scoliosis via myostatin signalling in fibro-adipogenic progenitors.
Sun H, Huang Y, Zhou H, Chen H, Dai J, Zhao J, Huang X, Cai H, Shen J
Journal of orthopaedic translation 2026 Jan;56:101027
Journal of orthopaedic translation 2026 Jan;56:101027
Dynamic expression of type III collagen in the lesion core of post-ischemic brain colocalizing with angiogenesis and lipid droplets during fibrotic scar formation.
Mutoh T, Kitajo K, Yamaguchi A
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 Jan;46(1):134-150
Comparing Effects of Short- and Long-Term Exposure of Cigarette Smoke Extract on Human Vocal Fold Fibroblasts.
Steffan B, Grossmann T, Grill M, Kirsch A, Groselj-Strele A, Gugatschka M
Journal of voice : official journal of the Voice Foundation 2026 Jan;40(1):149-159
Journal of voice : official journal of the Voice Foundation 2026 Jan;40(1):149-159
ACLP promotes hypertrophic scar pathogenesis by enhancing myofibroblast activation and cholesterol synthesis-related gene expression.
Shi Y, Song Y, Wang T, Jiao Y, Dang J, Zhang Y, Xiao S, Song B, Yu Z
Pathology, research and practice 2026 Jan;277:156311
Pathology, research and practice 2026 Jan;277:156311
Transcription factor ZEB2 is essential for ureteral smooth muscle cell differentiation.
Kumar S, Fan X, Pattam H, Yan K, Liaw EJ, Ji J, Zaltz E, Song P, Jiang Y, Nishizaki Y, Higashi Y, Cai CL, Lu W
PLoS genetics 2026 Jan;22(1):e1012028
PLoS genetics 2026 Jan;22(1):e1012028
7,8-Dihydroxyflavone Suppresses Experimental Pulmonary Fibrosis by Inhibiting Fibroblast-to-Myofibroblast Transformation and Epithelial-Mesenchymal Transition.
Song YC, Li QL, Liang RJ, Yao JT, Tian Z, Hu YW, Tan TT, Jia DX, Guo DD, Zhu H, Zhao J, Hang PZ
Basic & clinical pharmacology & toxicology 2026 Jan;138(1):e70158
Basic & clinical pharmacology & toxicology 2026 Jan;138(1):e70158
SLPI⁺ AT2-Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche.
Wang Z, Zhu G, Tang P, Wang Y, Luo W, Song W, Pan Z, Zheng B, Jiang Y, Xiao D, Jin X, Bai Y, Che G, Li W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e16580
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(6):e16580
Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cell.
Li B, Hou S, Tian T, Yuan S, Li A, Feng Y, Liu Z, Mi J, Cheng Z, Lv S, Yang J, Lu Y, Qi X, Song S, Zha Z, Yuan Q
Cell communication and signaling : CCS 2026 Jan 8;24(1):91
Cell communication and signaling : CCS 2026 Jan 8;24(1):91
The therapeutic potential of pirfenidone in alleviating fibrosis and restoring ovarian function in a novel ovarian endometriosis mouse model.
Gao Z, Chen Y, Xu X, Yang M, Wei P, Que X, Weng Y, Wang L, Ren L, Yan X, Chen Q, Wu R
Journal of translational medicine 2026 Jan 5;24(1):132
Journal of translational medicine 2026 Jan 5;24(1):132
Integrating BMSC-inlaid GelMA hydrogels and melatonin-loaded PLGA microspheres into silk fibroin/nanohydroxyapatite scaffolds to repair osteoporotic bone defects.
Lv J, Ma B, Li J, Wang Z
Journal of orthopaedic surgery and research 2026 Jan 5;21(1):86
Journal of orthopaedic surgery and research 2026 Jan 5;21(1):86
Adolescent high fructose consumption induces cardiac dysfunction in adulthood via elevated histone acetylation.
Shen AN, Shi HQ, Zhang ZH, Yao Y, Zhao R, Shi Y, Zhao JY, Cai K, Wang F
Translational pediatrics 2026 Jan 31;15(1):13
Translational pediatrics 2026 Jan 31;15(1):13
Design of RGD-functionalized GSH-responsive pegylated polymeric protacs for selective BRD4 degradation and EndMT-driven cardiac fibrosis inhibition.
Bi T, Chen L, Wang T, Miao W, Zhai S, Huang R, Sun Q, Chen Y, Su H, Zhou J, Li R, Huang W, Yao X, Luo P, Liu Z
Journal of nanobiotechnology 2026 Jan 30;24(1)
Journal of nanobiotechnology 2026 Jan 30;24(1)
Mechanically heterogeneous hydrogel with cell-programmed network restructuring promotes tissue regeneration by mechano-epigenetic modulation.
Ling Q, Li H, Zhao J, Guo W, Yu H, Li Z, Hu Y, Wei S, Fu Y, Zhang Y, Zhang K, Bian L
Nature communications 2026 Jan 30;17(1)
Nature communications 2026 Jan 30;17(1)
Suppressing Endothelial-Mesenchymal Transition Through the Histone Deacetylase 1/GATA Binding Protein 4 Pathway: The Mechanism of Protocatechuic Acid Against Myocardial Fibrosis Revealed by an Integrated Study.
Jin C, Shao C, Xu G, Wan H
Biology 2026 Jan 22;15(2)
Biology 2026 Jan 22;15(2)
Establishment of a three-dimensional in vitro peri-implant bone-mucosa composite model.
Malekahmadi B, Kheirmand-Parizi M, Mikolai C, Winkel A, Rahim MI, Doll-Nikutta K, Kampmann A, Gellrich NC, Wirth D, Menzel H, Stiesch M
BMC oral health 2026 Jan 14;26(1):91
BMC oral health 2026 Jan 14;26(1):91
Development of a Gelatin-Based Composite Hydrogel Powder with Kaolin and Sr-Doped Hydroxyapatite for Dual Hemostatic and Osteogenic Potential.
Jiang Y, Liang X
ACS omega 2026 Jan 13;11(1):1279-1292
ACS omega 2026 Jan 13;11(1):1279-1292
Guiqi Yishen granule alleviates obstructive nephropathy-induced renal fibrosis by targeting PI3K/AKT signaling pathway.
Zhu J, Cao S, Wang T, Wang N, Yang L, Tang X, Jiang M, Zhu Q, Yu H, Wu D, Peng WX
Journal of ethnopharmacology 2026 Jan 10;354:120490
Journal of ethnopharmacology 2026 Jan 10;354:120490
Potential regulators and metabolic networks of muscle fatty infiltration: genomic and radiomics investigation based on 33 300 participants.
Tan J, Ding Z, Zheng J, Zhang J, Chen X, Li Z, Shi L, Chen J, Sun Y
International journal of surgery (London, England) 2026 Jan 1;112(1):472-485
International journal of surgery (London, England) 2026 Jan 1;112(1):472-485
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Su Y, Fu Q, Wu X, Che X, Jiang Z, Li X
Toxicology and applied pharmacology 2026 Feb;507:117693
Toxicology and applied pharmacology 2026 Feb;507:117693
BMP1 inhibitor UK383367 improves MI-induced cardiac remodeling and fibrosis in mice via ameliorating macrophage polarization and mitochondrial dysfunction.
Guo CH, Wang QQ, Li JQ, Ji W, Chen L, Chang ML, Ma LY, Liu XL, Ni M
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Acta pharmacologica Sinica 2026 Feb;47(2):315-327
Polystyrene nanoplastics-induced lung epithelial cells ferroptosis promotes pulmonary fibrosis via YY1/FTL axis.
Bu W, Jin Y, Zhou Y, Wang F, Zheng D, Liu R, Wang X, Yu M, Bao S, Zhao R, Li J, Zhou X, Feng J, Zhao X, Cheng D
Materials today. Bio 2026 Feb;36:102738
Materials today. Bio 2026 Feb;36:102738
Betamethasone injection at different stages showing different effect on tendon-to-bone healing in a rat rotator cuff tear model.
Chen M, Xu H, Luo C, Wang H, Cheng J, Guo Y, Ju F, Sun Y, Zhu Z
Journal of shoulder and elbow surgery 2026 Feb;35(2):e344-e352
Journal of shoulder and elbow surgery 2026 Feb;35(2):e344-e352
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis.
Li S, He Z, Zhu R, Qiao W, Li Q, Miao Q, Liu L
Biomaterials 2026 Feb;325:123637
Biomaterials 2026 Feb;325:123637
Thymoquinone Protects Against Cardiac Hypertrophy via PPAR-γ/PI3K/Akt Pathway.
Qiu RB, Wu ZM, Xu ZQ, Hu LJ, Zhao ST, Zeng RY, Qiu ZC, Zhou LF, Lai SQ, Wang WJ, Wan L
Journal of cellular and molecular medicine 2026 Feb;30(3):e70911
Journal of cellular and molecular medicine 2026 Feb;30(3):e70911
Targeting Tumor Necrosis Factor-α Mitigates Glucose Fluctuation-Induced Aortic Valve Fibrosis: Insights From Diabetic Rat Models.
Chen YJ, Chen HP, Zhang CY, Rong XS, Li KL, Xiao F, Wang RX
Reviews in cardiovascular medicine 2026 Feb;27(2):42804
Reviews in cardiovascular medicine 2026 Feb;27(2):42804
Engineered probiotics for the in vivo mitigation of waterborne uranium toxicity and bioaccumulation.
Li H, Zhang F, Wang C, Cui Z, Liu Y, Song Z, Yuan L, Chen X, Wu Y, Wu W, Tian L
Environment international 2026 Feb;208:110127
Environment international 2026 Feb;208:110127
Engineered Gadolinium-Decorated Magnetic Resonance Nanoprobes for Enhanced Liver Fibrosis Theranostics.
Wang Y, Zhang Q, Yan B, Pang L, Ren Y, Inam M, Zhang M, Ni N, Xu X, Sun X, Zhou S
Advanced healthcare materials 2026 Feb;15(8):e03891
Advanced healthcare materials 2026 Feb;15(8):e03891
Biomimetic Multilayered Gas-Foaming Scaffold with Sustained bFGF Delivery for Annulus Fibrosus Regeneration.
Chen Y, Li Y, Wei Z, Du L, Qian M, Wang J, Mo X, Deng Z, Ye X, Yu J
Advanced healthcare materials 2026 Feb;15(7):e02833
Advanced healthcare materials 2026 Feb;15(7):e02833
A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.
Huang Y, Zhang Y, Feng Y, Yang Q, Gao B, Xu H, Huang C, Lin K, Xu Y, Zhu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e18796
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e18796
Autocrine Netrin-1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
Zhao J, Peng Y, Lei H, Wang T, Wang H, Wang B, Li J, Li X, Xiong X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e14545
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e14545
Activating the Osteoblastic USP26 Pathway Alleviates Multi-Organ Fibrosis by Decreasing Insulin Resistance.
Tang J, Ye W, He L, Dan Z, Chang L, You Z, Jiang Y, Tang G, Deng L, Li C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e12424
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(10):e12424
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
Jiang LJ, Zheng YY, Liang LM, Jia ZH, Du RH, Huang H, Dai X, Cheng PP, Zhao LQ, Li Q, Jiang YH, Cui XL, Ye SY, Hu SH, Zhang HD, Lian CY, Feng X, Song LJ, Yu F, He XL, Xiong L, Xiang F, Wang X, Liu AD, Wang M, Ye H, Ma WL
Respiratory research 2026 Feb 3;27(1)
Respiratory research 2026 Feb 3;27(1)
Targeted inhibition of RGS19 alleviates renal fibrosis by restoring autophagy and modulating immune cell infiltration.
Niu X, Zhao Y, Li L, Xu X, Xu C, Wu J, Yu X, Chen Y, Rong R, Xu B
Journal of nanobiotechnology 2026 Feb 28;24(1)
Journal of nanobiotechnology 2026 Feb 28;24(1)
Role of CTGF-LRP1 in impaired healing of cesarean section incisions.
He C, Ge S, Xia W, Wang Y, Yan L, Sun J, Yan L, Zhu Q, Zhao X, Zhang J
Nature communications 2026 Feb 28;17(1)
Nature communications 2026 Feb 28;17(1)
PLGA nanofibers carrying rhFGF1 for the effective treatment of skin wounds in diabetic mice.
Zhang Y, Wang X, Ye S, Li J, Wu J, Bao X, Zhao Y
BMC biotechnology 2026 Feb 25;26(1)
BMC biotechnology 2026 Feb 25;26(1)
STING deficiency alleviates scar formation after glaucoma filtration surgery by suppressing p38 MAPK-induced inflammation in mice.
Ye H, Lu X, Chen H, Yang X, Xu H, Huang L, Zheng Q, Le R, Liang Y
Eye and vision (London, England) 2026 Feb 2;13(1):7
Eye and vision (London, England) 2026 Feb 2;13(1):7
Synergistic microenvironment therapy: a dual-function nanogel of supramolecular collagen ll-mimetic matrix and antioxidant MXene for attenuating intervertebral disc degeneration.
Lyu G, Gao Z, Cao Z, Zhou Q, Chen Y, Yang S, Liang H, Lu X, Li S, Wang X, Sun S, Gao X, Zhou Y, Wu A, Zhou X, Wang X
Journal of nanobiotechnology 2026 Feb 19;24(1)
Journal of nanobiotechnology 2026 Feb 19;24(1)
Graphene oxide/sodium alginate/silk fibroin extracellular matrix-like sponge for acellular and growth factor-free bone regeneration.
Yang S, Wang F, Zhao H, Zhang Y, He W, Wang P, Fu C, Chen W, Zhu Y, Zhang Y
Carbohydrate polymers 2026 Feb 15;374:124535
Carbohydrate polymers 2026 Feb 15;374:124535
Identification and validation of the protective gene BCAT2 related to amino acid metabolism in idiopathic pulmonary fibrosis.
Zhu H, Chen M, Li Q, Cui S, Jiang C, Ye X, Hou S, Zhang J, Huang X, Cao M
Clinical and experimental medicine 2026 Feb 10;26(1):145
Clinical and experimental medicine 2026 Feb 10;26(1):145
Titanium ion inhibits osteogenic ability of osteoblasts by up-regulating osteoblast Agt gene via macrophages.
Wang MS, Zhou HF, Li H, Gao LN, Feng Y, Zhu H
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2026 Apr;94:127839
Shexiang Tongxin dropping pills attenuate cardiac remodeling in myocardial infarction rats by inhibiting Glycolysis via ITGB2 methylation.
Xu X, Sun L, Zhang H, Pan H, Zhai C
Cytotechnology 2026 Apr;78(2):53
Cytotechnology 2026 Apr;78(2):53
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
Zhu C, Jia S, Wang J, Gao F, Lin Y, Nie A, Guo Z, Zhou Z, Xu B, Lei H
Materials today. Bio 2026 Apr;37:102828
Materials today. Bio 2026 Apr;37:102828
Ultrasound-activated piezoelectric Silk-PVDF hydrogel reprograms the osteoimmune microenvironment via NRF2 signaling for accelerated bone regeneration.
Mo G, Qing L, Zhang C, Huang L, Yan H, Lu S, Zhang Y, Chen W, Xiang X, Wang N, Han G, Li Y, Jiang L, Zhang J
Materials today. Bio 2026 Apr;37:102779
Materials today. Bio 2026 Apr;37:102779
An engineered triple-network alginate/gelatin hydrogel mediates osteochondral regeneration through temporal regulation of the PI3K-AKT pathway.
Zhu Y, Leng P, Liang W, Xu W, Liang H, Yang Y, Si X, Liu X, Yang X, Shi C, Liu M
International journal of biological macromolecules 2026 Apr;358:151622
International journal of biological macromolecules 2026 Apr;358:151622
Lipid-modulating hyaluronic acid hydrogel promotes chondrogenesis of osteoarthritis progenitor cells for weight-bearing cartilage repair.
Liu W, Wang J, Wang W, Li M, Liu N, Luo M, Yao X
International journal of biological macromolecules 2026 Apr;353:151225
International journal of biological macromolecules 2026 Apr;353:151225
Inhibitory effect of Anwulignan on the IL-36R/TLR9 signaling pathway: potential therapeutic role in hepatic fibrosis.
Shang Y, Peng YG, Wang Y, Huo XK, Zhang HL, Hao TN, Ma XC
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157931
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157931
Protective Effects of Agrimonia pilosa Ledeb. In Myocardial Fibrosis: Inhibition of Mitophagy Mediated by the FOXO Signaling Pathway.
Chen J, Wei Z, An J, Li D, Gu Y, Zhang Y, Zhang M
Food science & nutrition 2026 Apr;14(4):e71778
Food science & nutrition 2026 Apr;14(4):e71778
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis.
Guo S, Wang Y, Lu B, Zhang Y, Frazer DM, Zhou B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16446
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e16446
TRIM21 Alleviates Alcoholic Liver Fibrosis by Inhibiting Ferroptosis Through Regulation of IDO1 Ubiquitination.
Zhong W, Luo L, Liu Y, Huang F, Meng Q, Deng G, Li Y, Liu X, Tong G, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71773
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71773
Dehydroepiandrosterone alleviates pulmonary fibrosis by modulating the TLR4/NF-κB/NLRP3 signaling cascade in macrophages.
Xie Q, Zhao X, Lu Y, Shuai S
The Journal of steroid biochemistry and molecular biology 2026 Apr 27;262:107028
The Journal of steroid biochemistry and molecular biology 2026 Apr 27;262:107028
Buyang Huanwu Decoction suppresses atherosclerosis by targeting IFITM1‑mediated lipid metabolism in vascular smooth muscle cells.
Huang Q, Tang X, Huang Q, Zhi S, Zheng X, Deng Q, Zhu J, Huang M, Pan Z, Hou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 20;156:158224
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 20;156:158224
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
Yu L, Zhai Z, Wang Y, Wang L, Li Q, Guo Y, Liang Y, Tang L
International immunopharmacology 2026 Apr 15;175:116448
International immunopharmacology 2026 Apr 15;175:116448
Beryllium Sulfate-Induced Cellular Senescence via the IL-6/STAT3 Pathway to Promote Pulmonary Fibrosis.
Lu Y, Li Y, Tong Y, Huang L, Zhang Z
Journal of applied toxicology : JAT 2026 Apr 13;
Journal of applied toxicology : JAT 2026 Apr 13;
1-O-acetylbritannilactone alleviates high-fat diet-induced fatty liver by covalently targeting NLRP3.
Jin T, Zhao Y, Xu T, Fang Y, Cui Y, Liu W, Xiong Y, Ye J, Luo W, Hong B, Liang G, Hu X, Huang L, Wang Y
International immunopharmacology 2026 Apr 1;174:116351
International immunopharmacology 2026 Apr 1;174:116351
Biphasic Scaffolds Functionalized with Piezoelectric Nanozymes for Osteochondral Defect Regeneration.
Ding H, Zhao C, Hu Y, Tong C, Gong X, Yang Y, Fang Y, Li J, Dai S, Chen W, Dong S
Advanced healthcare materials 2026 Apr 1;:e00012
Advanced healthcare materials 2026 Apr 1;:e00012
Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study.
Yang X, Wang X, Bao S, Li Z, Xing S, Du Z
Frontiers in toxicology 2025;7:1617663
Frontiers in toxicology 2025;7:1617663
Targeting p97/Valosin-Containing Protein Promotes Hepatic Stellate Cell Senescence and Mitigates Liver Fibrosis.
Yang Y, Zhang Y, Wang L, He G, Yang X, Qing J
DNA and cell biology 2025;44(3):132-143
DNA and cell biology 2025;44(3):132-143
SESN2 inhibits tubular exosome secretion and diabetic kidney disease progression by restoring the autophagy‒lysosome pathway.
Zheng Z, Chen J, Xue X, Ma X, Zhang S, Wang M, Xue Y, Jia Y
International journal of biological sciences 2025;21(9):4215-4230
International journal of biological sciences 2025;21(9):4215-4230
TAGLN-RhoA/ROCK2-SLC2A3-mediated Mechano-metabolic Axis Promotes Skin Fibrosis.
Cheng X, Gao Z, Zhang J, Zheng H, Shan S, Zhou J
International journal of biological sciences 2025;21(2):658-670
International journal of biological sciences 2025;21(2):658-670
GDF10 attenuates MASH progression by restoring quiescent hepatic stellate cells via competitive inhibition of TGF-β/SMAD2 signaling.
Peng Y, Lei H, Zhao J, Wang H, Luo Z, Wang D, Shi S, Wang T, Li J, Pang Z, Wang B, Xiong X
International journal of biological sciences 2025;21(15):6997-7012
International journal of biological sciences 2025;21(15):6997-7012
Inhibition of Mettl3 alleviates low-dose cisplatin-induced renal fibrosis and enhances the chemotherapeutic efficacy in mouse models of cancer.
Xie Y, Li H, Pan J, Li Y, Zhang D
International journal of biological sciences 2025;21(10):4293-4311
International journal of biological sciences 2025;21(10):4293-4311
Mechanical stretch-induced IGF2 overexpression in epidermal keratinocytes promotes hypertrophic scar formation through the IGF1R/p-c-Jun axis.
Zhu Y, Chen L, Song B, Cui Z, Chen G, Dou W, Jiao Y, Dang J, Yang Q, Yu Z, Song B
International journal of biological sciences 2025;21(1):109-127
International journal of biological sciences 2025;21(1):109-127
Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis.
Liu X, Wang H, Wang K, Liu Y
PloS one 2025;20(7):e0322639
PloS one 2025;20(7):e0322639
Transcriptomic and experimental evidence confirm the potential of disulfidptosis-related signature for the early diagnosis and treatment of liver cirrhosis.
Liu Y, Zhang R, Sun X, Cui W, Liu L
PloS one 2025;20(11):e0334459
PloS one 2025;20(11):e0334459
Tetrahedral Framework Nucleic Acids Inhibit Oxidative Stress and Cardiomyocyte Apoptosis in Doxorubicin-Induced Cardiotoxicity.
Pan H, Ye Q, Li Y, Ma L, Ni Y
International journal of nanomedicine 2025;20:9275-9289
International journal of nanomedicine 2025;20:9275-9289
Ginkgolide B Alleviates LPS-Induced Inhibition of Osteogenic Differentiation in Human Periodontal Ligament Stem Cells by Suppressing the p-IκBα/NF-κB Pathway.
Du S, Yang D, Liu Q, Yang P, Wu Z, Zhang Y, Chen S, Zhang J
Drug design, development and therapy 2025;19:8309-8326
Drug design, development and therapy 2025;19:8309-8326
ShenQi ShenKang Granule Alleviates Chronic Kidney Disease by Inhibiting the PI3K/AKT/mTOR Pathway and Restoring Autophagy Flux and Mitochondrial Integrity.
Xia C, Zhang J, Chen H, Zhou S, Jiang W, Zheng H, Lin Z, Tan Q, Sun W
Drug design, development and therapy 2025;19:3925-3947
Drug design, development and therapy 2025;19:3925-3947
Qimai Feiluoping Decoction Inhibits EndMT to Alleviate Pulmonary Fibrosis by Reducing PI3K/AKT/mTOR Pathway-Mediated the Restoration of Autophagy.
Ma J, Ding L, Zang X, Yang Y, Zhang W, Li X, Zhao D, Zhang Z, Wang Z, Zhao L, Tong X
Journal of inflammation research 2025;18:8447-8475
Journal of inflammation research 2025;18:8447-8475
Succinate Facilitates CD4(+) T Cell Infiltration and CCL1 Production to Promote Myofibroblast Activation and Renal Fibrosis in UUO Mice.
Tao Y, Zhang W, Liu D, Cao H, Yi X, Deng X, Li P, Shen X, Zhou H
Journal of inflammation research 2025;18:7827-7840
Journal of inflammation research 2025;18:7827-7840
SIRT1 Enhancement is Required for the Induction of Anti-Inflammatory Effect of Micheliolide in Carbon Tetrachloride Induced Liver Fibrosis in Mice.
Jin C, Jiang A, Chang J, Hu Y, Wang Y, Zhao R, Shi J, Wu H, Han Z, Liu Z
Journal of inflammation research 2025;18:16231-16245
Journal of inflammation research 2025;18:16231-16245
Cannabidiol Alleviates Intestinal Fibrosis in Mice with Ulcerative Colitis by Regulating Transforming Growth Factor Signaling Pathway.
Wang Y, Ji X, Wang X, Sun M, Li C, Wu D
Journal of inflammation research 2025;18:1-15
Journal of inflammation research 2025;18:1-15
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality.
Zhou X, Wang N, Wei J, Li G, Lue Z, Liu C, Bao Q, Feng Z, Zhang M, Huang H, Li Y, Wang J, Zhang X
Frontiers in pharmacology 2025;16:1732154
Frontiers in pharmacology 2025;16:1732154
Tibetan medicine Pa Zhu Wan ameliorates carbon tetrachloride-induced liver fibrosis in rats by regulating the TGF-β-Smad2/3 and IL-6/JAK2/STAT3 signaling pathways.
Zhao L, Jiang Y, Ma J, Yang Y, Liu G, Wang Z, Wong TW, Zhang D
Frontiers in pharmacology 2025;16:1667685
Frontiers in pharmacology 2025;16:1667685
Targeted ferroptosis of myofibroblasts by tubeimoside I attenuates hypertrophic scar formation.
Wang J, Wang C, Jia Y, Chen F, Wang Y, Du J
Frontiers in pharmacology 2025;16:1654108
Frontiers in pharmacology 2025;16:1654108
3D-cultured hADSCs-derived exosomes deliver circ_0011129 to synergistically attenuate skin photoaging.
Zhang Y, Zhou F, Nie G, Li L, Wen J, He S, Yao A
Frontiers in genetics 2025;16:1627472
Frontiers in genetics 2025;16:1627472
Lactobacillus rhamnosus GG attenuates MASLD/MASH progression by modulating gut microbiota and metabolic pathways.
Wang SL, Liang S, Li SY, Fu JW, Wang ZY, Zhu DQ, Chen N
Frontiers in microbiology 2025;16:1586678
Frontiers in microbiology 2025;16:1586678
Synergistic effects of retinol and retinyl palmitate in alleviating UVB-induced DNA damage and promoting the homologous recombination repair in keratinocytes.
Zhong J, Liang L, Zhao N, Wang J, Shu P
Frontiers in pharmacology 2025;16:1562244
Frontiers in pharmacology 2025;16:1562244
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model.
Ma Q, Feng X, Chen Y, Zhang J, Sun C
Frontiers in immunology 2025;16:1541577
Frontiers in immunology 2025;16:1541577
Roles of retinoic acid-related orphan receptor α in high glucose-induced cardiac fibroblasts proliferation.
San W, Zhou Q, Shen D, Cao D, Chen Y, Meng G
Frontiers in pharmacology 2025;16:1539690
Frontiers in pharmacology 2025;16:1539690
Yiqi Qingre Gao alleviates renal fibrosis in UUO mice via PI3K/AKT pathway.
Jin Q, Li Q, Yang L, Ma F, Mao H, Wang Y, Liu T, Peng L, Li P, Zhan Y
Frontiers in pharmacology 2025;16:1538061
Frontiers in pharmacology 2025;16:1538061
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b.
Hao J, Li H, Yu W
Frontiers in pharmacology 2025;16:1532517
Frontiers in pharmacology 2025;16:1532517
Role of integrin α4 in the inhibition of fibrosis in activated hepatic stellate cells by Periplaneta americana extract.
Fang Y, Liu Y, Li D, Miu Y, Chen K, Zhou J, Xie L, Chen X, Wu J, Zhu Y, Lv L, Li W
Frontiers in pharmacology 2025;16:1517491
Frontiers in pharmacology 2025;16:1517491
The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.
Ren X, Wang Z, Wang J, Li X, Wei H, Liu C, Liu S, Zhu Y, Feng C, Yin Y, Tian Y, Wu M, Zeng X
ImmunoTargets and therapy 2025;14:151-173
ImmunoTargets and therapy 2025;14:151-173
Receptor activity-modifying protein 1 regulates the differentiation of mouse skin fibroblasts by downregulating α-SMA expression via suppression of high mobility group AT-hook 1 to promote skin wound repair.
Song R, Ma J, Yin S, Wu Z, Liu C, Sun R, Cao G, Lu Y, Liu J, Su L, Wang Y
Burns & trauma 2025;13:tkae068
Burns & trauma 2025;13:tkae068
Meniscus progenitor cells combined with joint lavage promote meniscus regeneration and cartilage protection in rat models.
Guo SY, Zhu JH, Yan WT, Huang XJ, Xu WN, Wang JS, Zhang ZZ
Frontiers in bioengineering and biotechnology 2025;13:1724656
Frontiers in bioengineering and biotechnology 2025;13:1724656
IGF1R promotes radiation-induced HSCs activation by regulating DNA-PKcs-mediated DNA damage repair.
Lin J, Zhao G, Feng J, Sun C, Liu C, Li J, Shen Y, Cheng Y
Frontiers in cell and developmental biology 2025;13:1678654
Frontiers in cell and developmental biology 2025;13:1678654
Decoding HuH-7: a comprehensive genetic and molecular portrait of a widely used hepatocellular carcinoma model.
Luis DD, Liehr T, Kankel S, Weise A, Pentzold C, Buhl EM, Hardt KS, Keller DT, Schröder-Lange SK, Weiskirchen R
Frontiers in cell and developmental biology 2025;13:1648639
Frontiers in cell and developmental biology 2025;13:1648639
Restoration of tendon repair microenvironment by grapefruit exosome-loaded microneedle system for tendinopathy therapy.
Zhang Y, Zhang R, Zhang T, Mu Y, Juma T, Li X, Li H, Guo Q, Cao Y
Frontiers in bioengineering and biotechnology 2025;13:1615650
Frontiers in bioengineering and biotechnology 2025;13:1615650
Saliva-derived exosomes regulate fibroblast metabolic reprogramming in skin wound healing.
Song S, Xiang R, Chen S, Wu J, Chen W, Li X
Frontiers in cell and developmental biology 2025;13:1606716
Frontiers in cell and developmental biology 2025;13:1606716
Phytochemical nanozymes reprogram redox for balanced antimicrobial and regenerative therapy in acute and chronic diabetic wounds.
Pang Y, Amona FM, Chen X, You Y, Sha Z, Liu Z, Li J, Liu Y, Fang X, Chen X
Redox biology 2025 Sep;85:103718
Redox biology 2025 Sep;85:103718
The Paeonol of Total Glucosides of White Peony Regulates the Differentiation of CD4+Treg Cells through the EP300/Foxp3 Axis to Relieve Pulmonary Fibrosis in Mice.
Yan M, Wang Q, Yang H, Liu D, Liang W, Chen H
Cell biochemistry and biophysics 2025 Sep;83(3):3959-3970
Cell biochemistry and biophysics 2025 Sep;83(3):3959-3970
A mouse coccygeal intervertebral disc degeneration model with tail-looping constructed using a suturing method.
Xie W, Huang Z, Huang Z, Luo D, Chen Z, Xie L, Zhu L, Liu H, Lian K, Alberton P, Docheva D, Lin D
Animal models and experimental medicine 2025 Sep;8(9):1645-1655
Animal models and experimental medicine 2025 Sep;8(9):1645-1655
Diosmetin alleviates osteoarthritis through modulating the polarization of macrophages by inhibiting the PI3K/Akt signaling pathway.
Ren S, Zeng W, Du Z, Dai J, Li X, Wang H, Liu Y, Li R, Liu J
Journal of natural medicines 2025 Sep;79(5):1030-1043
Journal of natural medicines 2025 Sep;79(5):1030-1043
Noninsulated Microneedle Radiofrequency for Skin Rejuvenation: A Histological, Transcriptomic and Clinical Study.
Feng J, Huang L, Qi J, Ma S, Zhang L
Lasers in surgery and medicine 2025 Sep;57(7):608-617
Lasers in surgery and medicine 2025 Sep;57(7):608-617
Kaempferol Suppresses Mesothelial-Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF-α/COX2 Signalling Pathway.
Zhang L, Li G, Ren Y, Sun Y, Deng K, Cai L, Li E, Shen T, Li X, Zhou C
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70061
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70061
3D-printed advanced scaffold armed with exosomes derived from human skeletal stem cell identified by single-cell RNA sequencing enhances osteochondral regeneration.
Lou W, Qiu X, Qin Y, Lu Y, Cao Y, Lu H
Bioactive materials 2025 Sep;51:231-256
Bioactive materials 2025 Sep;51:231-256
Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression.
Deng K, Li M, Li Y, Xiang L, Wang Y, Shi H, Cheng J, Huang S, Lv Z
Journal of ginseng research 2025 Sep;49(5):574-584
Journal of ginseng research 2025 Sep;49(5):574-584
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Yan C, Li G, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Li Y, Sun Z, Tong Y, Yan C, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Self-Growing Scaffold for Spatial and Border Expansive Regeneration.
Gao L, Song X, Meng L, Wang J, Zhang H, Jiang X, Zhang W
Advanced materials (Deerfield Beach, Fla.) 2025 Sep;37(37):e2503057
Advanced materials (Deerfield Beach, Fla.) 2025 Sep;37(37):e2503057
Novel partial common bile duct ligation procedure in rats with reduced mortality and delayed onset of cirrhosis.
Xia W, Yao H, Mu T, Liu H, Chen J, Feng S, Wen S
Experimental and therapeutic medicine 2025 Sep;30(3):167
Experimental and therapeutic medicine 2025 Sep;30(3):167
Integrin αvβ6 mediates the effects of age-related decreases in matrix stiffness on Tenon's fibroblast activation and bleb scarring in glaucoma.
Feng L, Xiong W, Yin J, Guan D, Li H, Cao J, Zhu Z, Zhang W, Zhang F
Experimental eye research 2025 Sep;258:110459
Experimental eye research 2025 Sep;258:110459
Efficacy of Encorelane in Enhancing Barrier Function and Reducing Aging Signs in Sensitive Skin.
Wang L, Wang C, Jiang L, Hu H, Wu Y, Li Y, Sun P
Journal of cosmetic dermatology 2025 Sep;24(9):e70454
Journal of cosmetic dermatology 2025 Sep;24(9):e70454
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
Carbon black induced pulmonary fibrosis through piR-713551/PIWIL4 targeting THBS2 signal pathway.
Wang M, Niu Y, Liu Q, Yang P, Wu M, Wu R, Shi B, Chen J, Wang J, Du Z, Pang Y, Bao L, Niu Y, Zhang R
Journal of environmental sciences (China) 2025 Sep;155:409-422
Journal of environmental sciences (China) 2025 Sep;155:409-422
Sfrp2-deficient colonic fibroblasts drive mucosal inflammation and epithelial injury in ulcerative colitis.
Zhu M, Diao Z, Hu L, Fan Z
Cellular immunology 2025 Sep-Oct;415-416:105003
Cellular immunology 2025 Sep-Oct;415-416:105003
Wu Zi Yan Zong Wan Improves Triptolide-Induced Testicular Spermatogenic Dysfunction Through the Spermatogenic Microenvironment and the PLCγ/PKC Pathway.
Zhang L, Bao B, Wu W, Wen H, Tong S, Wang X, Liu B
American journal of men's health 2025 Sep-Oct;19(5):15579883251371990
American journal of men's health 2025 Sep-Oct;19(5):15579883251371990
5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.
Li J, Lu Y, Hu H, Han X, Pan Y, Sun K, Liu K, Yu Z
Lasers in medical science 2025 Sep 9;40(1):353
Lasers in medical science 2025 Sep 9;40(1):353
A two-stage transdermal drug delivery system comprising sono-phase-change transfersomes for non-invasive deep dermal delivery.
Zhang Y, He X, Mao X, Yang Y, Li F, Han X, Lu H, Tang L, Yang Y, Wang Y, Du Y, Xu W, Wang Z
Journal of nanobiotechnology 2025 Sep 29;23(1):621
Journal of nanobiotechnology 2025 Sep 29;23(1):621
Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.
Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y
Bone research 2025 Sep 24;13(1):79
Bone research 2025 Sep 24;13(1):79
The protective role of Agrin and CAF22 in hypertensive nephropathy.
Yuan C, Zhang P, Zhan Z, Guo Y, Huang P, Qian J, Wang W, Shan P
International immunopharmacology 2025 Sep 23;162:115107
International immunopharmacology 2025 Sep 23;162:115107
Colla Corii Asini regulate collagen regeneration in UV exposure-induced skin photoaging in mice.
Ma Y, Huang J, Gong J, Li L, Zhao Y, Jin Y, Gu J, Liu H, Wang Y, Sun Y
Chinese medicine 2025 Sep 22;20(1):146
Chinese medicine 2025 Sep 22;20(1):146
LINC02099 Promotes Retinal Extracellular Matrix Deposition in Diabetic Mice Via the miRNA-214-3p/CTSS Axis.
He Z, Peng X, Feng Y, Li Z, Lu J, Jia A, Bao Y, Li H
Investigative ophthalmology & visual science 2025 Sep 2;66(12):42
Investigative ophthalmology & visual science 2025 Sep 2;66(12):42
4EBP1 phosphorylation mediates TGF-β1-induced hepatic fibrosis and upregulates HIF-1α expression.
Shi Y, Lin Z, Zhang C, Cui J, Mao Y, Sun M, Zhao D, Nan Y, Sun D
iScience 2025 Sep 19;28(9):113412
iScience 2025 Sep 19;28(9):113412
Podoplanin-TGF-β1 Autocrine Loop: Pivotal Regulator of Islet Stellate Cell Activation via Cell Deformation, Orchestrating Islet Fibrosis in Diabetes.
Wang X, Wang Q, Yuan Y, Ni C, Cai Z, Qiu S, Li T, Chen Y, Wang J, Wang H, Carvalho V, Sun Z, Liu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70970
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70970
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
Cheng J, Jiang X, Deng Q, Ni L, Lin W, Cao W, Ren P, Xu B, Wang Q, Kuai J, Wu Y, Wei W, Wang C
European journal of pharmacology 2025 Sep 15;1003:177887
European journal of pharmacology 2025 Sep 15;1003:177887
Targeting interferon regulatory factor 7 alleviates renal fibrosis by inhibiting macrophage-to-myofibroblast transition.
Ren C, Mi T, Zhang Z, Jin L, Wang Z, Kong X, Luo J, Wang Q, He D
Life sciences 2025 Sep 1;376:123755
Life sciences 2025 Sep 1;376:123755
Proteins extracted from placenta regulate osteogenic differentiation of human mesenchymal stem cells.
Wei B, Chen Y, Zhang S, Cui L, Zhang S, Zhuang Z, Sun C, Ren N, Liu H
Tissue & cell 2025 Oct;96:103015
Tissue & cell 2025 Oct;96:103015
Dimethyloxalylglycine regulates osteogenesis of dental pulp stem cells through PI3K/AKT signaling pathways.
Dong Q, Zhang H, Zhang Q, Fei X, Ruan J, He L
Tissue & cell 2025 Oct;96:103012
Tissue & cell 2025 Oct;96:103012
Magnesium ions attenuate tendon graft fibrosis during its ligamentization after ACL reconstruction through modulation of fibroblast to myofibroblast trans-differentiation by promoting PGE2 secretion.
Xu C, Luo Y, Cai Z, Ji J, Guo Z, Cai Z, You C, Zhou Y, Chen Z, Zhang W, Gong N, Wang J
Bioactive materials 2025 Oct;52:474-491
Bioactive materials 2025 Oct;52:474-491
Bioengineered platelet nanoplatform enables renal-targeted dexamethasone delivery for chronic nephritis therapy with dual anti-inflammatory/anti-fibrotic effects and minimized systemic toxicity.
Zhang L, Gong H, Gong X, Zhou B, Wang X, Fei S, Xia D, Xu C, Huang X
Bioactive materials 2025 Oct;52:213-227
Bioactive materials 2025 Oct;52:213-227
CCP1 Inhibits Pulmonary Fibrosis by Suppressing Fibrotic Progression Through the EIF4B/PI3K/AKT Pathways.
Ren Q, Pan Y, Tian Z, Jiao G, Liu X
Cell biology international 2025 Oct;49(10):1245-1261
Cell biology international 2025 Oct;49(10):1245-1261
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
Li Y, Li Y, Li P, Yang L, Li H
Inflammation 2025 Oct;48(5):3326-3339
Inflammation 2025 Oct;48(5):3326-3339
Titanium surface modified with nanostructure mimicking the surface of natural cementum up-regulated epithelial expression of integrin β4 and enhanced the attachment of the transmucosal gingiva.
Deng Z, Yu L, Sun Y, Kuang Y, Zhou Z, Chen M, Li X
Dental materials : official publication of the Academy of Dental Materials 2025 Oct;41(10):1201-1212
Dental materials : official publication of the Academy of Dental Materials 2025 Oct;41(10):1201-1212
Canagliflozin-driven cellular re-differentiation and migration inhibition in vascular smooth muscle cells via PTEN upregulation.
Hsieh MJ, Chen DY, Lee CH, Liao YC, Lin MS, Pang JS
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14487-14500
Naunyn-Schmiedeberg's archives of pharmacology 2025 Oct;398(10):14487-14500
Investigating the Antifibrotic Action of Foeniculum vulgare Root Bark Volatile Oil Through the HK2/PKM2/LDHA Pathway.
Ming K, Peng L, Pan Y, Zhu M, Xiao Y, Ye S, Xu K, Liu X
Phytotherapy research : PTR 2025 Oct;39(10):4934-4949
Phytotherapy research : PTR 2025 Oct;39(10):4934-4949
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
Gao X, Wu S, Yao Z, Shao Y, Feng J, Yuan Z, Mao H
Materials today. Bio 2025 Oct;34:102104
Materials today. Bio 2025 Oct;34:102104
Isoimperatorin Reduces Synovial Inflammation and Fibrosis in Knee Osteoarthritis via the cAMP Signalling Pathway.
Jie L, Liu J, Zhu Z, Huang Z, Liu Y, Liu G, Shen X, Li Y, Shi X
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Journal of cellular and molecular medicine 2025 Oct;29(19):e70880
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Liu K, Huang Y, Xiao W, Liao J, Ouyang S, Liang Y, Fu J
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Multispectral Optoacoustic Tomography of Skeletal Muscle Unveils Microcirculation and Oxygen Metabolism Alterations in Sarcopenia.
Yang Y, Wu D, Xv Y, Xie Y, Wang X, Bi Y, Zhang J, Wu Y, Wen Y, Jiang S, Zhang Y, Peng T, Li Z, Chen J, Chen X, Wang B, Chen S, Yang M, Jiang H
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70088
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70088
Prrx1 promotes mesangial cell proliferation and kidney fibrosis through YAP in diabetic nephropathy.
Xu L, Shi J, Li H, Liu Y, Wang J, Li X, Ren D, Liu S, Wang H, Lu Y, Song J, Du L, Lu Q, Yin X
Journal of pharmaceutical analysis 2025 Oct;15(10):101247
Journal of pharmaceutical analysis 2025 Oct;15(10):101247
A Novel Injectable Composite Hydrogel HAp-GelMA Co-Doped Magnesium/Zinc Promotes Bone Generation and Angiogenesis Synergistically.
Qiang L, Zhang T, Zhang Q, Yang T, Shan J, Shen G, Kong W, Wei J, Wang J, Liu Y, Niu H, Zheng P
Advanced healthcare materials 2025 Oct;14(27):e01008
Advanced healthcare materials 2025 Oct;14(27):e01008
Identification of lactylation-related hub genes as novel therapeutic and diagnostic targets for thoracic aortic dissection.
Peng J, Jiang Z, Song J, Chen J, Fu Z, Zhang H, Zhen J, Tuerdi M, Luo M, Wu J, Sun T
Cellular signalling 2025 Oct;134:111944
Cellular signalling 2025 Oct;134:111944
TNALP promotes epithelial oxidative stress and fibrosis via SIRT3-dependent mechanisms in tracheal injury.
Liu Z, Peng H, Peng M, Liao J, Liu B, Zhuang R, Yang H, Xu L, Li Y, Gao L, Guo S
Cellular signalling 2025 Oct;134:111943
Cellular signalling 2025 Oct;134:111943
Angiotensin (1-7) decreases the fibrotic process by modulating the TGF-β1/AKT pathway in rat corpus cavernosum smooth muscle cells.
Xu Y, Lu Y, Liu G, Wang C, Tian S, Xiao H, Li W
Sexual medicine 2025 Oct;13(5):qfaf080
Sexual medicine 2025 Oct;13(5):qfaf080
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
Chen F, Peng F, Chen S, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jiang Z, Wang G, Jing X, Dong J, Li T, Xi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
Adaptive Antioxidant Nanomedicines Inhibit Ferroptosis in Renal Tubular Epithelial Cells to Alleviate Diabetic Kidney Disease.
Liu Z, Huang T, Hong Y, Yang Y, Chen W, Zeng Q, Chen Q, Yang Y, Ying X, Zeng W, Wu Z, Zhao T, Wan X, Chen J, Ai K, Huang Q
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e05168
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e05168
Liver-Targeted Scutellarin Nanoemulsion Alleviates Fibrosis with Ancillary Modulation of the Gut-Liver Microbiota.
Yu H, Niu X, Niu B, Lei P, Xu N, Yang S, Yu Q, Li G, Wang L
International journal of molecular sciences 2025 Oct 7;26(19)
International journal of molecular sciences 2025 Oct 7;26(19)
Injectable Immune-Regulating Mesenchymal Stem Cells Hydrogel for Localized Scleroderma Treatment.
Liu R, Kong B, Lu J, Zhao Y, Sun L
ACS nano 2025 Oct 7;19(39):34785-34796
ACS nano 2025 Oct 7;19(39):34785-34796
CAMKK2 restored mitochondrial dynamics homeostasis to alleviate pulmonary fibrosis via AMPK/PGC-1α signaling pathway in lung fibroblasts.
Zhou Y, Wang Y, Wang M, Li B, Xu K, Pan X, Li Z, Wang Q, He W, Pang J, Guo Y, Zhang Y, Sakamoto K, Yang J, Wang L, Yu G
Molecular medicine (Cambridge, Mass.) 2025 Oct 6;31(1):308
Molecular medicine (Cambridge, Mass.) 2025 Oct 6;31(1):308
Isolation and characterisation of AFP(+)/DLK1(+) double-positive hepatic stem/progenitor-like cells from fibrotic partial hepatectomy model.
Sun S, Badamjav T, Narid N, Xu U, Suo D, Batsaikhan B, Hexig B
Stem cell research & therapy 2025 Oct 31;16(1):602
Stem cell research & therapy 2025 Oct 31;16(1):602
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis.
Peng L, Zou Z, Zhou L, Li L, Lu W, Chen C, Xu Y, Liu Y, Lin J, Ye J
International immunopharmacology 2025 Oct 30;164:115347
International immunopharmacology 2025 Oct 30;164:115347
Luteoloside alleviates bleomycin-induced pulmonary fibrosis in mice via SIRT1-mediated protective effect against alveolar epithelial cell senescence.
Deng L, Sun B, Xia J, Zhuo W, Jiang M, Yin S, Yang F
Scientific reports 2025 Oct 29;15(1):37837
Scientific reports 2025 Oct 29;15(1):37837
Deletion of cardiac fibroblast growth factor-23 beneficially impacts myocardial energy metabolism in left ventricular hypertrophy.
Latic N, Lari A, Sun N, Zupcic A, Oubounyt M, Falivene J, Buck A, Hofer M, Chang W, Kuebler WM, Baumbach J, Walch AK, Grabner A, Erben RG
npj metabolic health and disease 2025 Oct 28;3(1):42
npj metabolic health and disease 2025 Oct 28;3(1):42
miR-34c-5p targets Notch2 to promote fracture healing.
Li K, Liu G, Chen F, Sun X, Liu B
Journal of orthopaedic surgery and research 2025 Oct 24;20(1):924
Journal of orthopaedic surgery and research 2025 Oct 24;20(1):924
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury.
Ding L, Wang X, Liu Q, Zhang Y, Wu X, Xiao B, Liu D, Chen L, Zeng H, Zhao B, Dong C, Li L, Ge G, Jia L, Ni S
Journal of medicinal chemistry 2025 Oct 23;68(20):21458-21478
Journal of medicinal chemistry 2025 Oct 23;68(20):21458-21478
Hesperetin alleviates liver fibrosis by improving intestinal microbiota composition and regulating hepatic stellate cell autophagy.
Li X, Xu J, Ren Z, Lu J, Wu X, Wu S, Xu J
European journal of pharmacology 2025 Oct 15;1005:178106
European journal of pharmacology 2025 Oct 15;1005:178106
Isorhapontigenin alleviates pulmonary fibrosis by inhibiting oxidative stress-induced senescence via STAT3/PRDX2 signals in alveolar epithelial cells.
Chen S, Yuan A, Fan S, Ding X, Zhang S, Li Y, Dai J
International immunopharmacology 2025 Oct 10;163:115287
International immunopharmacology 2025 Oct 10;163:115287
Faecalibacterium prausnitzii alleviates Graves' orbitopathy by modulating short-chain fatty acid (SCFA) metabolism and inhibiting orbital fibrosis and adipogenesis.
Qi X, Zhang J, Li Y, Shi Y, Yao J, Tong B
Archives of biochemistry and biophysics 2025 Nov;773:110588
Archives of biochemistry and biophysics 2025 Nov;773:110588
Holistic regulation of the diabetic osteo-microenvironment via NIR-II nanocarriers with dual NO/pH responsiveness for enhanced bone regeneration.
Xie X, Yang J, Ding C, Li Y, Ai-Smadi F, Zha K, Lin C, Lin Z, Yu C, Zeng R, Hu W, Liao J, Ouyang L, Xia T, Zhao P, Mi B, Liu G
Bioactive materials 2025 Nov;53:754-772
Bioactive materials 2025 Nov;53:754-772
YOD1 mediates isoproterenol-induced cardiac remodeling by deubiquitinating PKM2 and reducing PKM2 tetramerization in cardiomyocytes.
Zheng QS, Xiong YQ, Xu JC, Qian JF, Luo W, Wang QY, Zhao YN, Luo Y, Cui YQ, Fang Y, Guo XC, Chen DD, Wang Y, Liang G
Acta pharmacologica Sinica 2025 Nov;46(11):2938-2950
Acta pharmacologica Sinica 2025 Nov;46(11):2938-2950
Protamine-loaded quaternized chitosan hydrogel dressing featuring antibacterial and antioxidant properties for promoting postoperative periodontal wound healing.
Huang Y, Yan Z, Chen H, Chen L, Huang Y, Liu X, Wang D, Pan Y, Guo L
International journal of biological macromolecules 2025 Nov;330(Pt 4):148259
International journal of biological macromolecules 2025 Nov;330(Pt 4):148259
Bispecific aptamers target thyrotropin receptor (TSHR) and insulin growth factor-1 receptor (IGF-1R) for the improvement of orbital fibroblasts activation in the treatment of thyroid-associated ophthalmopathy.
Xie B, Zhang F, Yin J, Ouyang S, Cao J, Tan Y, Xiong W
International journal of biological macromolecules 2025 Nov;330(Pt 1):147867
International journal of biological macromolecules 2025 Nov;330(Pt 1):147867
Porous chitin nanofibers combined with adipose-derived stem cells promote diabetic wound healing via PPAR-γ activation.
Zhang Z, Zheng Y, Wang Z, Li Y, Liu Y, Luo Z
International journal of biological macromolecules 2025 Nov;330(Pt 1):147763
International journal of biological macromolecules 2025 Nov;330(Pt 1):147763
Osteoclasts drive bone formation in ectopic and orthotopic environments.
Zhang Y, Yu T, Xiang Q, van den Tillaart F, Ma J, Zhuang Z, Stessuk T, Wang H, van den Beucken JJJP
Biomaterials 2025 Nov;322:123377
Biomaterials 2025 Nov;322:123377
Timosaponin B- II Enhances Osteogenic Differentiation of Human Periodontal Ligament Stem Cells via PI3K/AKT/GSK3β Signaling Pathway.
Yang DW, Cui XB, Dong R, Wu ZY, Zhang YX, Yang P, Zhang J
Stem cell reviews and reports 2025 Nov;21(8):2675-2692
Stem cell reviews and reports 2025 Nov;21(8):2675-2692
Autophagic degradation of SQSTM1 enables fibroblast activation to accelerate wound healing.
Xu Y, Gu X, Li W, Lin B, Xu Y, Wei Q, Liu Q, Zhao Y, Long R, Jiang H, Wu Z, Liu Y, Qiang L
Autophagy 2025 Nov;21(11):2401-2421
Autophagy 2025 Nov;21(11):2401-2421
An Ile to Met polymorphism in ADCY9 promotes airway obstruction and remodeling in asthma.
Liang LM, Cai PC, Yu F, He XL, Song LJ, Lu YZ, Niu Q, Zhou YY, Jiang LJ, Jiang YH, Jia ZH, Zhao LQ, Wang M, Cheng PP, Chen SJ, Feng X, Li Q, Cui XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168015
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168015
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
Lai J, Hu D, Yan M, Chen Q, Shi H, Yang Q, Ding M, Li L, Zhang H, Bai L
Biomaterials advances 2025 Nov;176:214358
Biomaterials advances 2025 Nov;176:214358
3D Differentiation of Bone-Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting.
Taoum A, Friede R, Thaden O, Rachynskyi O, Frank A, Wang M, Dehli F, Fuest M, Duarte Campos D
Advanced healthcare materials 2025 Nov;14(28):e2405073
Advanced healthcare materials 2025 Nov;14(28):e2405073
Neoeriocitrin Targeting Beclin1 Deubiquitination and Autophagy in Osteogenic Differentiation of Human Dental Pulp Stem Cells.
Wu Y, Liu H, Wang Q, Zhang T, Chen R, Yuan Q, Tong X, Yang W, Xiao Y, Yan F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e04378
The Composite Antiadhesion Barrier Facilitated Fibroblast Autophagy Activation for Tendon Repair.
Sun Z, Liu J, Chen L, Wang Z, Wang F, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(41):e06204
High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis.
Yao J, Ke H, Huang G, Wang X, Li Z, Shao Y, Chen H, Pan J, Cai D, Zeng C
Bone & joint research 2025 Nov 7;14(11):969-983
Bone & joint research 2025 Nov 7;14(11):969-983
High-throughput Generation of Collagen Microbeads for Extracellular Vesicle Production and Therapeutic Delivery.
Ali S, Mastantuono F, Orozco-Torres A, Barua N, Zhou X, Wu L, He M
Advanced materials technologies 2025 Nov 30;
Advanced materials technologies 2025 Nov 30;
IGF1-mediated mesenchymal-endothelial transition as a potential regulatory target in calcific aortic valve disease.
Li B, Zhou M, Guo J, Kuang T, Lyu T, Zhu D, Wang X
BMC medicine 2025 Nov 3;23(1):600
BMC medicine 2025 Nov 3;23(1):600
Extracellular matrix anchored neutrophils drive pulmonary fibrosis in mice.
Yang L, Sun P, Wang J, Xu M, Zhu B, Yu K, Rong Y, Mao R, Zi S, Liu C, Huang J, Ma J, Chen H, Luo W, Zhang W, Zhang X, Fang S, Chao J
Nature communications 2025 Nov 26;16(1):11655
Nature communications 2025 Nov 26;16(1):11655
Kaempferol ameliorates BMSCs senescence in postmenopausal osteoporosis by targeting Sp1 to activate FUNDC1-mediated mitophagy.
Wang L, Qu Y, Hu Z, Lei P, Tian X, Yang X, Chen S, Li C, Wei B, Li L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157456
Shenqi compound ameliorates renal fibrosis in diabetic kidney disease by inhibiting LRG1/TGF-β/Smad signaling pathway.
Yuan Y, Liu L, Chen N, Tang S, Qi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157355
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157355
Directed rescue strategy for enhanced implant osteointegration in aged rats.
Li X, Jiang X, He Y, Xiong H, Huang Q, Xu K, Luo XX, Li K, Tao B, Zha K, Wu J, Liu P, Cai K
Nature communications 2025 Nov 24;16(1):10322
Nature communications 2025 Nov 24;16(1):10322
Reconstruction of the lymphatic system by transplantation of a centrifuge-based bioengineered lymphatic tissue.
Obana S, Itakura S, Murahashi M, Nishikawa M, Kusamori K
Nature communications 2025 Nov 19;16(1):10154
Nature communications 2025 Nov 19;16(1):10154
Loss of LCAT function aggravates metabolic-associated steatohepatitis (MASH) in golden Syrian hamster.
Zhang Y, Wang H, Wang F, Guo X, Zhao M, Zhou Z, Lin X, Zheng L, Wang Y, Liu G, Lu G, Xian X, Dong Z
Clinical science (London, England : 1979) 2025 Nov 17;129(22):1507-25
Clinical science (London, England : 1979) 2025 Nov 17;129(22):1507-25
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Huang J, Zhang W
BMC pulmonary medicine 2025 Nov 14;25(1):528
BMC pulmonary medicine 2025 Nov 14;25(1):528
Sotagliflozin attenuates atrial oxidative stress and the susceptibility to atrial fibrillation by activating the NRF2/HO-1 pathway.
Li F, Xie M, Zeng G, Zhu J, Zhou J, Tan S, Lin Q, Liu Q
International immunopharmacology 2025 Nov 14;165:115461
International immunopharmacology 2025 Nov 14;165:115461
The influences of antihistamine on liver fibrosis, vasoresponsiveness, and portosystemic shunting in bile duct-ligated cirrhotic rats.
Chang CL, Chang CC, Chuang CL, Hsu SJ, Tsai MH, Tsai CJ, Chang YY, Hou MC, Lee FY
Journal of the Chinese Medical Association : JCMA 2025 Nov 1;88(11):825-835
Journal of the Chinese Medical Association : JCMA 2025 Nov 1;88(11):825-835
Poricoic Acid A attenuated TGF-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells through SPRY2/ERK signaling pathway.
Xiang M, Chen H, Lin X
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Nov 1;29(6):727-739
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2025 Nov 1;29(6):727-739
Repurposing of FDA-approved drugs by targeting SIRT2 to alleviate inflammatory response and kidney injury.
Huang HJ, Lin YC, Ho LJ, Su RY, Liu WC, Chiu HW
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Nov 1;214:107296
Radiation Induces Pericyte-Myofibroblast Transition.
Yamazaki T, Jordan KR, Fox N, Young KH
International journal of radiation oncology, biology, physics 2025 Nov 1;123(3):860-875
International journal of radiation oncology, biology, physics 2025 Nov 1;123(3):860-875
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
LA-peptide Hydrogel-Regulation of macrophage and fibroblast fates and their crosstalk via attenuating TGF-β to promote scarless wound healing.
Li Z, Zhang L, Wang Y, Zhu Y, Shen H, Yuan J, Li X, Yu Z, Song B
Bioactive materials 2025 May;47:417-431
Bioactive materials 2025 May;47:417-431
Dihydroartemisinin requires NR1D1 mediated Rab7 ubiquitination to regulate hepatic stellate cells lipophagy in liver fibrosis.
Bao Z, Xu M, Kan Y, Guo X, Li M, Wang J, Zhou Y, Zhang Z, Shao J, Zhang F, Chen L, Zheng S, Xuan J
International journal of biological macromolecules 2025 May;305(Pt 1):141055
International journal of biological macromolecules 2025 May;305(Pt 1):141055
A Keap1-recruiting BRD4 degrader offers a single-molecular polypharmacology approach for the treatment of metabolic dysfunction-associated steatohepatitis.
Zhang X, Ge Y, Ye M, Wang X, Tong Y, Liu C, Xu S, Zhao Z, You Q, Guo X, Jiang Z
Free radical biology & medicine 2025 May;232:15-27
Free radical biology & medicine 2025 May;232:15-27
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
Dai Y, Wang C, Xiao Y, Tan Y, Ye Y, Liu Y, Zeng Q, Tan J
Archives of oral biology 2025 May;173:106194
Archives of oral biology 2025 May;173:106194
Porcine plasma protein cold-set hydrogel crosslinked by genipin and the immunomodulatory, proliferation promoting and scar-remodeling in wound healing.
Li H, Wu M, Ma Z, Wang X, Fan J, Hu K, Wei Y, Yao C, Liu J, Kang S, Kang X, Yuan J
Biomaterials advances 2025 May;170:214216
Biomaterials advances 2025 May;170:214216
Network pharmacology combined with experimental analysis to explore the mechanism of the XinShuaiNing formula on heart failure.
Zhao J, Han M, Nie Q, Wen X, Geng H, Zou Y, Li S, Xie W
3 Biotech 2025 May;15(5):110
3 Biotech 2025 May;15(5):110
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
Zheng J, Du Y, Shao W, Li J, Zhao P, Zhang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
13-Methylpalmatine alleviates bleomycin-induced pulmonary fibrosis by suppressing the ITGA5/TGF-β/Smad signaling pathway.
Mao Q, Liu J, Yan Y, Wang G, Zhang M, Wang Z, Wen X, Jiang Z, Li H, Li J, Xu M, Zhang R, Yang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156545
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156545
Engrailed-1 inactivation leads to scarless skin wound healing through extracellular matrix remodeling.
Hao A, Dong X, Gou Y, Li A, Li J, Xiang H, Rahaman S, Zhu Y, Zhang H, You W, Shen G, Luo C, Mei O, Wu X, Shi LL, Reid RR, He TC, Fan J
Genes & diseases 2025 May;12(3):101484
Genes & diseases 2025 May;12(3):101484
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization.
Qiu H, Liu J, You J, Zhou O, Hao C, Shu Y, Ma D, Zou W, Zhang L, Liu E, Luo Z, Ren L, Geng G, Zou L, Peng D, Fu Z
Genes & diseases 2025 May;12(3):101244
Genes & diseases 2025 May;12(3):101244
Enhancing Tendon Regeneration: Investigating the Impact of Topography on the Secretome of Adipose-Derived Stem Cells.
Long Q, Liu C, Zheng H, Wang M, Liu H, Liu Y, Cao Z, Sun Y, Mo Q, Backman LJ, Zhu J, Hu L, Huang J, Zhang W, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2417447
CILP1 interacting with YBX1 promotes hypertrophic scar formation by suppressing PPARs transcription.
Wang J, Du J, Song Y, Tan X, Wu J, Wang T, Shi Y, Xu X, Yu Z, Song B
Cell death & disease 2025 May 9;16(1):371
Cell death & disease 2025 May 9;16(1):371
Pulmonary Injury Induced via Metal-Organic Frameworks (MOFs): ROS Generation and Inflammatory Responses Mediated by HKUST-1.
Zhang Y, Xue Z, Yang Z, Chen M, Zhou L, Zhou L, Zhu M, Huang Z, Li Y, Kang S, Zheng L, Zhang D
ACS omega 2025 May 6;10(17):17865-17874
ACS omega 2025 May 6;10(17):17865-17874
SMYD2 Promotes Renal Tubular Cell Apoptosis and Chronic Kidney Disease Following Cisplatin Nephrotoxicity.
Zuo S, Yuan H, Li X, Chen M, Peng R, Chen S, Zou X, Yang Y, Long H, Liu Z, Wang T, Guo B, Liu L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70651
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 May 31;39(10):e70651
Decellularised amniotic membrane-TDSCs composite promotes Achilles tendon healing.
Mao X, Wang Y, Zhang X, Yao Z, Yuan Z, Yao L, Wang L, Mao H
Scientific reports 2025 May 3;15(1):15556
Scientific reports 2025 May 3;15(1):15556
Serum-free endothelial cell culture medium for vascular smooth muscle cells sheet formation.
Yang J, Sun X, Jiang H, Li J, Liang J, Lin Z
Journal of biological engineering 2025 May 28;19(1):51
Journal of biological engineering 2025 May 28;19(1):51
LncRNA SYISL promotes fibroblast myofibroblast transition via miR-23a-mediated TRIOBP regulation.
Xia C, Cheng L, Zhao W, Chang A, Wang Z, Liu H, Pan X, Li W, Koji S, Li Z, Li B, Wang L, Yu G
Cellular and molecular life sciences : CMLS 2025 May 27;82(1):214
Cellular and molecular life sciences : CMLS 2025 May 27;82(1):214
Superoxide Anion (O(2)(-•)) Leading to Pulmonary Toxicity of Metal-Organic Frameworks (MOFs).
Zhang Y, Zhang Y, Yang Z, Xue Z, Zhou L, Chen M, Zhu M, Wu Q, Li Y, Kang S, Zheng L, Zhang D
Langmuir : the ACS journal of surfaces and colloids 2025 May 27;41(20):12510-12519
Langmuir : the ACS journal of surfaces and colloids 2025 May 27;41(20):12510-12519
Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis.
Peng B, Guo X, Kang J, Pan S, Wei L, Wang L, Li B, Han G, Cheng Y
Journal of translational medicine 2025 May 27;23(1):593
Journal of translational medicine 2025 May 27;23(1):593
Identifying and Targeting Key Driver Genes for Collagen Production within the 11q13/14 Breast Cancer Amplicon.
Araiza-Olivera D, Prudnikova TY, Uribe-Alvarez C, Cai KQ, Franco-Barraza J, Dones JM, Raines RT, Chernoff J
Molecular cancer research : MCR 2025 May 2;23(5):405-415
Molecular cancer research : MCR 2025 May 2;23(5):405-415
Vascular grafts with a mimetic microenvironment extracted from extracellular matrix of adipocytes can promote endothelialization in vivo.
Wang J, Xu M, Liu H, Wang D, Zhang H, Xu Z, Shi X, Liu X, Tan Z
Acta biomaterialia 2025 May 15;198:49-62
Acta biomaterialia 2025 May 15;198:49-62
The surface protein Gbp of Fusobacterium nucleatum inhibits osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2.
Dong R, Li M, Gu XF, Gao H, Wei Z, Qi H, Zhang J, Feng Q
Journal of translational medicine 2025 May 14;23(1):540
Journal of translational medicine 2025 May 14;23(1):540
Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms.
Zhang J, Li Z, Song X, Cai P, Liu Q
Scientific reports 2025 May 13;15(1):16664
Scientific reports 2025 May 13;15(1):16664
Exploring the wound-healing mechanism of Cayratia japonica extract: A combined experimental and network pharmacology study.
Cheng M, Hou Y, Chen Q, Ge S, Chen C, Zheng X, Zhang C
Journal of ethnopharmacology 2025 May 12;347:119810
Journal of ethnopharmacology 2025 May 12;347:119810
GAMG alleviates liver fibrosis through inducing ferroptosis in inflammatory macrophages via the IRF1/SLC7A11 signaling pathway.
Pang Q, Zhou S, Wang Y, Pan H, Wang Z, Qin X, Zhu C, Chen S, Liu H, Hu X, Jin H
Redox biology 2025 Mar;80:103509
Redox biology 2025 Mar;80:103509
TRPV4 as a Novel Regulator of Ferroptosis in Colon Adenocarcinoma: Implications for Prognosis and Therapeutic Targeting.
Ren X, Chen W, Liu Y, Chen Z, Wang X, Sun X
Digestive diseases and sciences 2025 Mar;70(3):1064-1077
Digestive diseases and sciences 2025 Mar;70(3):1064-1077
Exploring the mechanism of tiRNA-Val-CAC-002 in the pathogenesis of oral submucous fibrosis.
Zeng L, Peng H, Sun L, Yu H, Wu Y
Journal of oral biosciences 2025 Mar;67(1):100588
Journal of oral biosciences 2025 Mar;67(1):100588
LINC00525 promotes cell proliferation and collagen expression through feedforward regulation of TGF-β signaling in hypertrophic scar fibroblasts.
Chen L, Yin Y, Li J, Li Q, Zhu Z, Li J
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
Burns : journal of the International Society for Burn Injuries 2025 Mar;51(2):107353
ADAMTS13 attenuates renal fibrosis by suppressing thrombospondin 1 mediated TGF-β1/Smad3 activation.
Guo J, Zhou S, Wang H, Qiu X, Dong F, Jiang S, Xu N, Cui Y, Liu R, Li P, Ma Z, Zhao L, Lai EY
Toxicology and applied pharmacology 2025 Mar;496:117260
Toxicology and applied pharmacology 2025 Mar;496:117260
Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC.
Wang J, Lv ZY, Li P, Zhang Y, Li X, Shen DF
Molecular and cellular biochemistry 2025 Mar;480(3):1611-1625
Molecular and cellular biochemistry 2025 Mar;480(3):1611-1625
A derivative of tanshinone IIA and salviadione, 15a, inhibits inflammation and alleviates DSS-induced colitis in mice by direct binding and inhibition of RIPK2.
Hu CH, Chen Y, Jin TY, Wang Z, Jin B, Liao J, Ding CY, Zhang A, Tang WY, Zhang LX, Xu LY, Ning FM, Liang G, Wei XH, Wang Y
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Acta pharmacologica Sinica 2025 Mar;46(3):672-686
Osteomimix: A Multidimensional Biomimetic Cascade Strategy for Bone Defect Repair.
Wu X, Yang H, Liu G, Sun W, Li J, Zhao Y, Gao X, Liu X, Song F, Wang S, Lu Z, Chen C, Huang C
Advanced materials (Deerfield Beach, Fla.) 2025 Mar;37(11):e2416715
Advanced materials (Deerfield Beach, Fla.) 2025 Mar;37(11):e2416715
Shenmai Injection Reduces Cardiomyocyte Apoptosis Induced by Doxorubicin through miR-30a/Bcl-2.
Zhang XN, Li YY, Lyu SC, Jia QJ, Zhang JP, Liu LT
Chinese journal of integrative medicine 2025 Mar;31(3):240-250
Chinese journal of integrative medicine 2025 Mar;31(3):240-250
Methacrylated silk fibroin based composite hydrogel with ROS-scavenging and osteogenic ability to orchestrate diabetic bone regeneration.
Wang R, He X, Su S, Bai J, Liu H, Zhou F
International journal of biological macromolecules 2025 Mar;294:138945
International journal of biological macromolecules 2025 Mar;294:138945
CD39 Contributes to the Ability of Cell Invasion in Heterogeneity of Colorectal Cancer.
Li X, Shen Y, Lang J, Wu J, Qian Z, Shen G, Shen Y
Journal of cellular and molecular medicine 2025 Mar;29(5):e70486
Journal of cellular and molecular medicine 2025 Mar;29(5):e70486
p16INK4a Deletion Alleviated Obesity-Associated Kidney Fibrosis by Regulating Metabolic Reprogramming and the Inflammasome Pathway.
Liu Q, Wang F, Du Y, Liu Y, Zhang Z, Zhang X, Li J, Huang G, Liu F, Li B, Xiao W, Sui C, Bao N, Zhuang R, Gao C, Wang X, Gu X
Journal of cellular and molecular medicine 2025 Mar;29(5):e70444
Journal of cellular and molecular medicine 2025 Mar;29(5):e70444
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis.
Wang M, Li W, Shao Y, Wang F, Huang Y, Wei C, Li P, Sun K, Yan X, Gou Z
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119919
Biochimica et biophysica acta. Molecular cell research 2025 Mar;1872(3):119919
Intravenous injection of PCSK9 gain-of-function mutation in C57BL/6J background mice on Angiotensin II-induced AAA.
Xu X, Li X, Zhai C, Yao Y, Li X, Ming C, Sun J, Wang H, Mao Y, Zhang L
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167657
Exosomes derived from fibroblasts in DFUs delay wound healing by delivering miR-93-5p to target macrophage ATG16L1.
Xu Z, Ni T, Zhang Q, Sun X, Zhao L, Lin J, Gao W, Yi M, Zhang L, Tu L, Wu G, Yan W
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167640
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167640
1-benzyl-6-nitro-4-phenyl-4-(methoxycarbonyl)-2(1H)-pyridinone, a novel pirfenidone derivative, alleviate hepatic fibrosis through T cells.
Hu MX, Li JQ, Zhang HW, Ma YK, Zhao BJ, Xiao L, Liang W, Wang Y, Wang C, Wu CG, Liu TT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Mar;184:117907
The role of fibromodulin in myocardial fibrosis in a diabetic cardiomyopathy rat model.
Dai X, Yang F, Chen D, Yang L, Dong Z, Chen C, Xiao J
FEBS open bio 2025 Mar;15(3):436-446
FEBS open bio 2025 Mar;15(3):436-446
Nitazoxanide protects against heart failure with preserved ejection and metabolic syndrome induced by high-fat diet (HFD) plus L-NAME "two-hit" in mice.
Chen J, Zhang L, Xie T, Zhang X, Pan C, Sun F, Li W, Sun Z, Dong D
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1397-1414
Acta pharmaceutica Sinica. B 2025 Mar;15(3):1397-1414
Improved Black Phosphorus Nanocomposite Hydrogel for Bone Defect Repairing: Mechanisms for Advancing Osteogenesis.
Wu A, Ma G, Chen Y, Gui H, Sun B, Zhang B, Liu Y, Zhang S, Lian G, Song D, Zhang D
Advanced healthcare materials 2025 Mar;14(7):e2404934
Advanced healthcare materials 2025 Mar;14(7):e2404934
Highly expressed VGLL3 in keloid fibroblasts promotes glycolysis and collagen production via the activation of Wnt/β-catenin signaling.
Liu Y, Yang Z, Lin N, Liu Y, Chen H
Cellular signalling 2025 Mar;127:111604
Cellular signalling 2025 Mar;127:111604
Extracellular vesicle-packaged PKM2 from endometriotic stromal cells promotes endometrial collagen I deposition by inhibiting autophagy in endometriosis.
Zhu Y, Gao L, Zhang J, Li M, Zhou J, Zhou J
Cellular signalling 2025 Mar;127:111523
Cellular signalling 2025 Mar;127:111523
Targeting the E Prostanoid Receptor EP4 Mitigates Cardiac Fibrosis Induced by β-Adrenergic Activation.
Xu H, Mao X, Wang Y, Zhu C, Liang B, Zhao Y, Zhou M, Ye L, Hong M, Shao H, Wang Y, Li H, Qi Y, Yang Y, Chen L, Guan Y, Zhang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2413324
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2413324
Evenly Distributed Microporous Structure and E7 Peptide Functionalization Synergistically Accelerate Osteogenesis and Angiogenesis in Engineered Periosteum.
Li Q, Li C, Yan J, Zhang C, Jiang Y, Hu X, Han L, Li L, Wang P, Zhao L, Zhao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2406084
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2406084
Extracellular Mitochondrial-Derived Vesicles Affect the Progression of Diabetic Foot Ulcer by Regulating Oxidative Stress and Mitochondrial Dysfunction.
Zhang H, Yan Z, Zhu J, Li Z, Chen L, Zheng W, Dai Z, Yang J, Yun X, Wang Y, Zhou H, Jiang Z, Yu Q, Li S, Huang W, Yang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2407574
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2407574
Reticulophagy promotes EMT-induced fibrosis in offspring's lung tissue after maternal exposure to carbon black nanoparticles during gestation by a m(5)C-dependent manner.
Du Z, Liu Q, Wang M, Gao Y, Li Q, Yang Y, Lu T, Bao L, Pang Y, Wang H, Niu Y, Zhang R
Journal of hazardous materials 2025 Mar 5;485:136873
Journal of hazardous materials 2025 Mar 5;485:136873
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
Xu Y, Li G, Liu W, Ge D, Hao Z, Wang W
Urolithiasis 2025 Mar 4;53(1):44
Urolithiasis 2025 Mar 4;53(1):44
Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA(+) macrophages contribute to atherosclerotic plaque formation.
Li M, Wu L, Wen Y, Wang A, Zhou X, Ren L, Lu Q, Li F, Zhu L, Tang C
Cellular and molecular life sciences : CMLS 2025 Mar 30;82(1):134
Cellular and molecular life sciences : CMLS 2025 Mar 30;82(1):134
Genetic and Molecular Characterization of H9c2 Rat Myoblast Cell Line.
Liehr T, Kankel S, Hardt KS, Buhl EM, Noels H, Keller DT, Schröder-Lange SK, Weiskirchen R
Cells 2025 Mar 28;14(7)
Cells 2025 Mar 28;14(7)
Targeted Degradation of Bromodomain-Containing Protein 4 Enabled by Reactive Oxygen Species-Activatable NanoPROTACs as an Efficient Strategy to Reverse Liver Fibrosis in Chronic Liver Injury.
Bi T, Liang P, Zhao Q, Wu J, Zhou Y, Xu Y, Fan X, Yang G, Sun Q, Ren W, Yang Y, Liu Z
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Journal of medicinal chemistry 2025 Mar 27;68(6):6328-6338
Molecular mechanisms and therapeutic targets in glioblastoma multiforme: network and single-cell analyses.
Chen X, Zhong X, Zhang F, Zhou X, Yue X, Li X
Scientific reports 2025 Mar 27;15(1):10558
Scientific reports 2025 Mar 27;15(1):10558
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Cheng Y, Song T, Yao J, Wang Q, Meng C, Feng F
Scientific reports 2025 Mar 27;15(1):10548
Scientific reports 2025 Mar 27;15(1):10548
Phosphatase PHLPP1 is an alveolar-macrophage-intrinsic transcriptional checkpoint controlling pulmonary fibrosis.
Jiang Y, Zhang Y, Wang X, Xiang Y, Wang Z, Wang B, Ding Y, Gao Y, Rui B, Bai J, Ding Y, Chen C, Zhan Z, Liu X
Cell reports 2025 Mar 25;44(3):115399
Cell reports 2025 Mar 25;44(3):115399
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition.
Wu Y, Zhu W, Wang L, Zhang W, Zhang K, Sun M, Guan J, Liu S, Liu Y
European journal of pharmacology 2025 Mar 15;991:177333
European journal of pharmacology 2025 Mar 15;991:177333
Ciliary neurotrophic factor (CNTF) contributes to pelvic organ prolapse by modulating collagen expression via the JAK2-STAT3 pathway.
Xu Z, Zhu Q, Yang Y, Shan W, Jiang F, Zou Q, Wang W
Journal of molecular histology 2025 Mar 14;56(2):107
Journal of molecular histology 2025 Mar 14;56(2):107
Static Topographical Cue Combined with Dynamic Fluid Stimulation Enhances the Macrophage Extracellular Vesicle Yield and Therapeutic Potential for Bone Defects.
Huang H, Xiao L, Fang L, Lei M, Liu Z, Gao S, Lei Q, Lei J, Wei R, Lei Y, Xue L, Geng Z, Cai L, Yan F
ACS nano 2025 Mar 11;19(9):8667-8691
ACS nano 2025 Mar 11;19(9):8667-8691
Trbp inhibits cardiac fibrosis through TGF-β pathway-mediated cross-talk between cardiomyocytes and fibroblasts.
Pan B, Hu D, Lu YW, Luo J, Xu XH, Guo H, Deng R, Liang Z, Wang Y, Ma Q, Mably JD, Tian J, Wang DZ
Clinical science (London, England : 1979) 2025 Mar 11;139(5):1-14
Clinical science (London, England : 1979) 2025 Mar 11;139(5):1-14
Astilbin Alleviates Radiation-Induced Pulmonary Fibrosis via circPRKCE Targeting the TGF-β/Smad7 Pathway to Inhibit Epithelial-Mesenchymal Transition.
Shi Z, Liu J, Qin J, Liang X, Ou X, Zhang T, Yan X, Hu Q, Huang W, Hu K
Biomedicines 2025 Mar 11;13(3)
Biomedicines 2025 Mar 11;13(3)
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Chang J, Lu J, Liu Q, Xiang T, Zhang S, Yi Y, Li D, Liu T, Liu Z, Chen X, Dong Z, Li C, Yi H, Yu S, Huang L, Qu F, Wang M, Wang D, Dong H, Cheng G, Zhu L, Li J, Li C, Wu P, Xie X, Teschendorff AE, Lin D, Wang X, Wu C
Cancer cell 2025 Mar 10;43(3):380-397.e7
Cancer cell 2025 Mar 10;43(3):380-397.e7
Harnessing Anti-Inflammatory and Regenerative Potential: GelMA Hydrogel Loaded with IL-10 and Kartogenin for Intervertebral Disc Degeneration Therapy.
Yang S, Shi J, Qiao Y, Teng Y, Zhong X, Wu T, Liu C, Ge J, Yang H, Zou J
ACS biomaterials science & engineering 2025 Mar 10;11(3):1486-1497
ACS biomaterials science & engineering 2025 Mar 10;11(3):1486-1497
Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model.
Ha AW, Sudhadevi T, Jafri A, Mayer C, MacFarlane PM, Natarajan V, Harijith A
Pediatric research 2025 Jun;97(7):2462-2474
Pediatric research 2025 Jun;97(7):2462-2474
Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.
Wang W, Jiang C, Chen JH, Chen YL, Zhang ZW, Yang ZC, Li J, Li XC
JOR spine 2025 Jun;8(2):e70061
JOR spine 2025 Jun;8(2):e70061
Beneficial effects of Akkermansia muciniphila on benign prostatic hyperplasia and metabolic syndrome.
Wu S, Yin X, Yang P, Gong B, Wang Z
Archives of biochemistry and biophysics 2025 Jun;768:110294
Archives of biochemistry and biophysics 2025 Jun;768:110294
A thermosensitive hydrogel with synergistic stromal targeting and antitumor immunity modulation for pancreatic cancer immunotherapy.
Zhao G, Guo F, Yan W, Qu Y, Yan C, Lv H, Li G, Zhao J, Xie H, Li Y, Tian T, Zhao Z
Materials today. Bio 2025 Jun;32:101882
Materials today. Bio 2025 Jun;32:101882
A novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration.
Su S, Bai J, Wang R, Gao S, Zhou R, Zhou F
Materials today. Bio 2025 Jun;32:101759
Materials today. Bio 2025 Jun;32:101759
Polyvinyl alcohol/graphene oxide/dextran hydrogel doped copper oxide modified biochar with nano-enzymatic activity and multiple synergistic effects for accelerated diabetic wound healing.
Yang J, Ding C, Ding Q, Zhang S, Chai G, Wei H, Li D, Sui Q, Liu W, Liang D, Zhao T
International journal of biological macromolecules 2025 Jun;315(Pt 1):144480
International journal of biological macromolecules 2025 Jun;315(Pt 1):144480
Lycium barbarum polysaccharide alleviate cadmium-induced mitochondrial dysfunction mediated pyroptosis in duck liver.
Song J, Luo X, Xiong L, Li S, Chen Y, Liu W, Yuan Y, Ma Y, Bian J, Liu Z, Zou H
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
International journal of biological macromolecules 2025 Jun;311(Pt 4):143989
P4HB, a novel succinated protein, is essential for fumarate-induced cancer metastasis.
Song X, Rao H, Huang C, Huang M, Ma Y, Xin J, Hou J, Hu Z, He L, Pan F, Yang L, Guo Z
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
International journal of biological macromolecules 2025 Jun;311(Pt 3):143885
Shuangshi Tonglin Capsule Improves Prostate Fibrosis through Nrf2/TGF-β1 Signaling Pathways.
Wang ZQ, Mao P, Wang BA, Guo Q, Liu H, Yuan Y, Wang C, Liu JP, Zhu XM, Wei H
Chinese journal of integrative medicine 2025 Jun;31(6):518-528
Chinese journal of integrative medicine 2025 Jun;31(6):518-528
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Acetylation of H3K18 activated by p300 promotes osteogenesis in human adipose-derived mesenchymal stem cells.
Zeng L, Chen C, Xiong Y, Liu Y, Huang M, Ye J, Zhong J, Peng W
Biochemical pharmacology 2025 Jun;236:116901
Biochemical pharmacology 2025 Jun;236:116901
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Zhou Y, Yang G, Liu J, Yao S, Jia J, Tang X, Gong X, Wan F, Wu R, Zhao Z, Liang H, Liu L, Liu Q, Xie S, Long X, Xiang X, Wang G, Xiao B
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Neferine reduces synovial inflammation and cardiac complications in a collagen-induced arthritis mouse model via inhibiting NF-κB/NLRP3 inflammasome axis.
Cao J, Zhang H, Ni Y, Ning X
Molecular immunology 2025 Jun;182:117-125
Molecular immunology 2025 Jun;182:117-125
A 3D Co-Culture System Inspired by Fracture Healing Cell Interactions for Bone Tissue Engineering.
Wu J, Wang Y, Wang L, Xie W, Wan Q, Wang J, Chen J, Pei X, Zhu Z
Advanced healthcare materials 2025 Jun;14(16):e2500534
Advanced healthcare materials 2025 Jun;14(16):e2500534
Injectable Alginate/β-TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis.
Zhou YH, Zou ZH, Teng JX, Wu ZY, Luo SW, Ning X, Ye C, Yang L, Toh WS
Advanced healthcare materials 2025 Jun;14(15):e2500617
Advanced healthcare materials 2025 Jun;14(15):e2500617
FP receptor inhibits autophagy to aggravate aging-related cardiac fibrosis through PI3K/AKT/mTOR signaling pathway.
Qi J, Lu B, Jin CW, Shang YY, Pan H, Li H, Tong ZJ, Zhang W, Han L, Zhong M
Archives of gerontology and geriatrics 2025 Jun;133:105824
Archives of gerontology and geriatrics 2025 Jun;133:105824
MTFR2-Mediated Fission Drives Fatty Acid and Mitochondrial Co-Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis.
Zhang L, Zhou B, Yang J, Ren C, Luo J, Li Z, Liu Q, Huang Z, Wu Z, Jiang N
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2416419
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2416419
Molecular adaptations in MMP genes support lung elasticity and diving adaptations in cetaceans.
Zhang Y, Lv W, Yan W, Guo B, Yang G, Ren W
BMC genomics 2025 Jun 5;26(1):562
BMC genomics 2025 Jun 5;26(1):562
Inhibition of Matrix Metalloproteinase-7 Attenuates Subpleural Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease.
Xiong L, Liang LM, Ye SY, Cui XL, Hu SH, Lian CY, Sun WJ, Lv YP, Zhang HD, Wang M, Xiang F, Xiong L, Ye H, Ma WL, Song LJ
Biomedicines 2025 Jun 27;13(7)
Biomedicines 2025 Jun 27;13(7)
Heshuxiaoji pill suppresses steatohepatitis and fibrosis by regulating the AngII-BACH1 mediated vasoconstriction.
Pu Y, Ren W, Gan Z, Wang S, Peng M, Yue R, Huang R
Journal of ethnopharmacology 2025 Jun 26;350:119989
Journal of ethnopharmacology 2025 Jun 26;350:119989
Network pharmacology and bioinformatics analysis reveals: NXC improves cardiac lymphangiogenesis through miR-126-3p/SPRED1 regulating the VEGF-C axis to ameliorate post-myocardial infarction heart failure.
Xu J, Wang C, Xu Y, Wang H, Wang X
Journal of ethnopharmacology 2025 Jun 26;350:119959
Journal of ethnopharmacology 2025 Jun 26;350:119959
Rebastinib attenuates acute lung injury by promoting NLRP3 ubiquitination and blocking NLRP3/GSDMD signaling pathway in macrophages and protecting alveolar epithelial cells.
Wang L, Chen H, Lu C, Ding Y, He Y, Xu J, Xu J, Zhang Z
International immunopharmacology 2025 Jun 26;159:114819
International immunopharmacology 2025 Jun 26;159:114819
Notch3 enhances the synergistic effect of all-trans retinoic acid and calcipotriol in pancreatic stellate cell activation.
Lian Z, Du WH, Tusup-Han PG, Zhang YX
Journal of translational medicine 2025 Jun 22;23(1):694
Journal of translational medicine 2025 Jun 22;23(1):694
Celastrol alleviates esophageal stricture in rats by inhibiting NLR family pyrin domain containing 3 activation.
Zhang MX, Wu C, Feng XX, Tian W, Zhao NH, Lu PP, Ding Q, Liu M
World journal of gastroenterology 2025 Jun 21;31(23):106949
World journal of gastroenterology 2025 Jun 21;31(23):106949
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
Xanthine oxidase inhibitor allopurinol preserves cardiac function after experimental malocclusion induced by occlusal disharmony in mice.
Mitsubayashi T, Suita K, Ohnuki Y, Ishikawa M, Ito A, Matsuo I, Miyamoto G, Abe M, Morii A, Mototani Y, Nariyama M, Matsubara R, Hayakawa Y, Okumura S
The journal of physiological sciences : JPS 2025 Jul;75(2):100029
The journal of physiological sciences : JPS 2025 Jul;75(2):100029
Sequential construction of vascularized and mineralized bone organoids using engineered ECM-DNA-CPO-based bionic matrix for efficient bone regeneration.
Gai T, Zhang H, Hu Y, Li R, Wang J, Chen X, Wang J, Chen Z, Jing Y, Wang C, Bai L, Wang X, Su J
Bioactive materials 2025 Jul;49:362-377
Bioactive materials 2025 Jul;49:362-377
Immune-modulated adhesive hydrogel for enhancing osteochondral graft adhesion and cartilage repair.
Zhou J, Ji X, Xue Y, Yang W, Zhong G, Zhou Z, Chen X, Lei Z, Lu T, Zhang Y, Liu J, Ma L
Bioactive materials 2025 Jul;49:23-38
Bioactive materials 2025 Jul;49:23-38
Mechanistic Insights Into 5'-tiRNA-His-GTG Mediated Activation of the JNK Pathway in Skin Photoaging.
Liu L, Xu Z, Dai X, Zhou X, Chen L, Luan C, Huang D, Chen H, Zhang J, Hu Y, Chen K
Aging cell 2025 Jul;24(7):e70049
Aging cell 2025 Jul;24(7):e70049
The mechanism of action of GLUT1 in promoting NETs-mediated impairment of macrophage phenotypic switching based on macrophage-fibroblast interplay.
Li W, Li S, Sun W, Han D
Cytokine 2025 Jul;191:156946
Cytokine 2025 Jul;191:156946
Stiffness regulates extracellular matrix synthesis in fibroblasts by DDR1-TGF-β/STAT3 mechanotransduction axis.
Han X, Zhang C, Lei Q, Xu J, Zhou Y
Biomaterials advances 2025 Jul;172:214240
Biomaterials advances 2025 Jul;172:214240
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection.
Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
Acta pharmaceutica Sinica. B 2025 Jul;15(7):3663-3684
CD11b Blockade Ameliorates Myocardial Ischemia/Reperfusion Injury by Reducing Neutrophil and Monocyte Infiltration.
Fu P, Han X, Lin QY, Wang N, Sun FF, Zhang YL, Li HH, Zhang B
Journal of the American Heart Association 2025 Jul;14(13):e038142
Journal of the American Heart Association 2025 Jul;14(13):e038142
Exploring the molecular mechanisms through which overexpression of TET3 alleviates liver fibrosis in mice via ferroptosis in hepatic stellate cells.
Liu Y, Feng LL, Han B, Cai LJ, Liu RY, Tang S, Yang Q
Cellular signalling 2025 Jul;131:111747
Cellular signalling 2025 Jul;131:111747
Inhibition of RACK1-Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome.
Cui J, Yang M, Yu C, Zhang H, Gong Y, Hu Y, Wang Y, Yuan Q, Pan A, Li J, Hu Y, Jin Z, Peng X, Wu A, Wang J, Wang Q, Zhang Y, Hu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2411355
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2411355
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization.
Xuan C, Chen D, Zhang S, Li C, Fang Q, Chen D, Liu J, Jiang X, Zhang Y, Shen W, Cai G, Chen X, Li P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2414587
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2414587
Dermal papilla cells-conditioned medium attenuates oxidative stress-induced senescence via ferroptosis inhibition.
Ru Z, Wu Y, Qu Q, Miao Y, Zhu L, Hu Z
Scientific reports 2025 Jul 9;15(1):24789
Scientific reports 2025 Jul 9;15(1):24789
Benzothiazole amide analogues as antagonists of TRPC 6 channels: A therapeutic approach for kidney fibrosis.
Ren C, Xu Q, Luo Q, Qiao X, Ding T, Wang W, Zeng X, Chen C, Xiao Y, Hong X
European journal of medicinal chemistry 2025 Jul 5;291:117628
European journal of medicinal chemistry 2025 Jul 5;291:117628
Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages.
Kang B, Jia Z, Li W, Zhang W
Pharmaceutics 2025 Jul 30;17(8)
Pharmaceutics 2025 Jul 30;17(8)
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Wu Y, Zhang T, Miao Y, Zhang A, Wang S, Li X, Liu H, Guo Y, Sun Q, Li Z
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
Identifying fibroblast-derived sFRP2 as a therapeutic target and engineering siRNA therapy for uterine scarring.
Cheng J, Zhang S, Gui Q, Pu Z, Chen Z, Wei Q, Qi H, Zhang J
Nature communications 2025 Jul 25;16(1):6850
Nature communications 2025 Jul 25;16(1):6850
Gluconic acid alleviates hypertrophic scar formation through binding PLOD1, reducing p-AKT signaling and activating autophagy.
Li J, Zeng S, Sun Y, Zou J, Zhang E, Yan Q, Chen L, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156825
Bioactive fraction of processed Curcumae Rhizoma-Sparganii Rhizoma anti-liver fibrosis by regulate taurine metabolism through PI3K/AKT pathway.
Hao M, Chen Z, Wang P, Lu Y, An D, Yang Q, Han X, Wang K, Sang X, Cao G
Journal of ethnopharmacology 2025 Jul 24;351:120090
Journal of ethnopharmacology 2025 Jul 24;351:120090
Maternal obesity impairs fetal brown adipogenesis by attenuating fetal FGF21 signaling.
Hua L, Shen W, Gao D, Yang Y, Yang X, Zhang H, Liu S, Liu L, Cao Y, Jiang X, Han X, Jin C, Feng B, Che L, Xu S, Lin Y, Li J, Fang Z, Luo T, Li M, Wu D, Zhuo Y
Cell reports 2025 Jul 22;44(7):115935
Cell reports 2025 Jul 22;44(7):115935
Growth hormone combined with estrogen improves intrauterine adhesion fibrosis by downregulating endometrial microbial citraconic acid to target β-catenin protein.
Zeng Y, Yang Y, Zeng F, Feng Q
mSystems 2025 Jul 22;10(7):e0169224
mSystems 2025 Jul 22;10(7):e0169224
Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.
Xu W, Gao W, Zhang Y, Hou G, Zhang W, Deng J, Wang K, Xu Y, Liu B, Xu T, Liu C, Liang T
Journal of nanobiotechnology 2025 Jul 21;23(1):531
Journal of nanobiotechnology 2025 Jul 21;23(1):531
GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis.
Zhao W, Cao H, Xu W, Duan Y, Gan Y, Huang S, Cao Y, Long S, Zhang Y, Yu G, Wang L
Biomolecules 2025 Jul 20;15(7)
Biomolecules 2025 Jul 20;15(7)
Exploring PU.1 as a Therapeutic Target to Mitigate Oxidative Stress and Inflammation in Peritoneal Dialysis-Induced Peritoneal Fibrosis.
Zhong S, Su W, Wang Y, Liu D, Li X, Ma F, Xu L, Gao J, Wang H, Sun J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70766
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 15;39(13):e70766
Blocking calcium-MYC regulatory axis inhibits early dedifferentiation of chondrocytes and contributes to cartilage regeneration.
Wu X, Fu Y, Ma J, Wang H, Li C, Zhu Y, Wang Q, Guo X, Zhang T, He A
Stem cell research & therapy 2025 Jul 15;16(1):372
Stem cell research & therapy 2025 Jul 15;16(1):372
Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing.
Fu Y, Xie JL, Zhang XL, Xie GM, Zhang XM, Han YT, Xu MM, Zhang J, Zhang J
Journal of nanobiotechnology 2025 Jul 14;23(1):506
Journal of nanobiotechnology 2025 Jul 14;23(1):506
Alleviation of fibrosis and oxidative stress in pressure overload-induced cardiac remodeling and heart failure via SIRT3 activation by colchicine.
Wu M, Chen G, Peng Y, Luo S
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Biochemical and biophysical research communications 2025 Jul 12;770:151957
Dendrobium officinale-derived nanovesicles: a natural therapy for comprehensive regulation of angiogenesis, inflammation, and tissue repair to enhance skin wound healing.
Tu J, Xu L, Guo Y, Zhang M, Gan M, Bao X, Yang R, Liu H, Lin F
Bioresources and bioprocessing 2025 Jul 12;12(1):74
Bioresources and bioprocessing 2025 Jul 12;12(1):74
Identification and analysis of extracellular matrix and epithelial-mesenchymal transition-related genes in idiopathic pulmonary fibrosis by bioinformatics analysis and experimental validation.
Huang X, Yu W, Tian J, Zhang Y, Wei A, Li Y, Chen S
Gene 2025 Jul 10;956:149464
Gene 2025 Jul 10;956:149464
ALKBH5 regulates intrauterine adhesion progression through m6A dependent FABP4 mRNA stabilization and serum lipid metabolism.
Yang X, Feng Q
Communications biology 2025 Jul 1;8(1):973
Communications biology 2025 Jul 1;8(1):973
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid-Associated Orbitopathy-Like Features Through the JAK/STAT Signaling Pathway.
Liu R, Xin X, Ma S, Guo J, Wu C, Qi X, Luo B
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
Investigative ophthalmology & visual science 2025 Jul 1;66(9):68
Biodegradable Zn-xY alloys with enhanced osteogenesis and angiogenesis effects for bone implant applications.
Liang S, Du S, Zheng Y, Xia D, Zhou Y
Acta biomaterialia 2025 Jul 1;201:684-702
Acta biomaterialia 2025 Jul 1;201:684-702
Comparison of the effects of Liraglutide, Tirzepatide, and Retatrutide on diabetic kidney disease in db/db mice.
Ma J, Hu X, Zhang W, Tao M, Wang M, Lu W
Endocrine 2025 Jan;87(1):159-169
Endocrine 2025 Jan;87(1):159-169
Moderate static magnetic field regulates iron metabolism and salvage bone loss caused by iron accumulation.
Zhen C, Wang S, Yang J, Zhang G, Cai C, Wang J, Wang A, Xu Y, Fang Y, Wei M, Yin D, Luo X, Gong M, Zhang H, Shang P
Journal of orthopaedic translation 2025 Jan;50:144-157
Journal of orthopaedic translation 2025 Jan;50:144-157
Localization of α-smooth muscle actin in osteoblast differentiation during periodontal development.
Takebe H, Sato H, Mizoguchi T, Hosoya A
Cell and tissue research 2025 Jan;399(1):119-127
Cell and tissue research 2025 Jan;399(1):119-127
Topography immune-responsive silk films for skin regeneration.
Yang F, Wang Y, Yang D, Zheng X, Xie X, Feng K, Cheng G, Hu Q, Chai C, Zhang Q
International journal of biological macromolecules 2025 Jan;287:138543
International journal of biological macromolecules 2025 Jan;287:138543
Sympathetic nerve promotes renal fibrosis by activating M2 macrophages through β2-AR-Gsa.
Liu L, Deng Y, Li Q, Cai Y, Zhang C, Zhang T, Xu G, Han M
Clinical immunology (Orlando, Fla.) 2025 Jan;270:110397
Clinical immunology (Orlando, Fla.) 2025 Jan;270:110397
ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion.
Bai R, Liang B, Guo Y, Liu W, Wen Z, Wang Z, Zhang Y, Du J, Song Y, Yu Z, Ma X
Journal of cosmetic dermatology 2025 Jan;24(1):e16767
Journal of cosmetic dermatology 2025 Jan;24(1):e16767
Betulin gel alleviates esophageal stricture following endoscopic submucosal dissection: an animal study.
Ma D, Yang F, Yu Q, Zhou X, Li Z, Wang Y, Chen J
Esophagus : official journal of the Japan Esophageal Society 2025 Jan;22(1):105-114
Esophagus : official journal of the Japan Esophageal Society 2025 Jan;22(1):105-114
Magnesium-Impregnated Membrane Promotes Bone Regeneration in Rat Skull Defect by N-Linked Glycosylation of SPARC via MagT1.
Chen W, Lu H, Yu W, Huang L, Bian M, Wang N, Xiang X, Mo G, Zhang C, Li Y, Jiang L, Zhang J
Advanced healthcare materials 2025 Jan;14(2):e2402705
Advanced healthcare materials 2025 Jan;14(2):e2402705
Inhibition of PKM2 by shikonin impedes TGF-β1 expression by repressing histone lactylation to alleviate renal fibrosis.
Xiang T, Wang X, Huang S, Zhou K, Fei S, Zhou B, Yue K, Li Q, Xue S, Dai Y, Zhang J, Ni H, Sun C, Huang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156324
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156324
Single-cell RNA sequencing reveals the heterogeneity of myofibroblasts in wound repair.
Liu M, Liu X, Zhang J, Liang S, Gong Y, Shi S, Yuan X
Genomics 2025 Jan;117(1):110982
Genomics 2025 Jan;117(1):110982
Copper ions-photo dual-crosslinked alginate hydrogel for angiogenesis and osteogenesis.
Liu G, Ye S, Li Y, Yang J, Wang S, Liu Y, Yang S, Tian Y, Yin M, Cheng B
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37790
Journal of biomedical materials research. Part A 2025 Jan;113(1):e37790
The CLCA1/TMEM16A/Cl- current axis associates with H2S deficiency in diabetic kidney injury.
Lee HJ, Sun Y, Das F, Ju W, Nair V, Kevil CG, Varadarajan S, Zhang G, Ghosh Choudhury G, Singh BB, Kretzler M, Nelson RG, Sharma K, Kasinath BS
JCI insight 2025 Jan 9;10(1)
JCI insight 2025 Jan 9;10(1)
Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection: A natural ingredient strategy.
Zhou X, Ma D, He YX, Jin J, Wang HL, Wang YF, Yang F, Liu JQ, Chen J, Li Z
World journal of gastroenterology 2025 Jan 7;31(1):98561
World journal of gastroenterology 2025 Jan 7;31(1):98561
Exploring the molecular mechanisms for renoprotective effects of Huangkui capsule on diabetic nephropathy mice by comprehensive serum metabolomics analysis.
Yan X, Li P, Liu C, Yin F, Han J, Sun H, Zheng Y, Chen X, Guan S, Wang X
Journal of ethnopharmacology 2025 Jan 31;340:119223
Journal of ethnopharmacology 2025 Jan 31;340:119223
Baricitinib represses the myocardial fibrosis via blocking JAK/STAT and TGF-β1 pathways in vivo and in vitro.
Feng R, Liu H, Chen Y
BMC cardiovascular disorders 2025 Jan 31;25(1):65
BMC cardiovascular disorders 2025 Jan 31;25(1):65
Comparison of chemical composition between imitation wild and transplanted Astragali Radix and their therapeutic effects on heart failure.
Zhang C, Zhu Y, Wang M, Chen R, Sun X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118827
Inhibition of HIF-1α ameliorates pulmonary fibrosis by suppressing M2 macrophage polarization through PRMT1/STAT6 signals.
Liang J, Ran Y, Hu C, Zhou J, Ye L, Su W, Liu Z, Xi J
International immunopharmacology 2025 Jan 27;146:113931
International immunopharmacology 2025 Jan 27;146:113931
Adipose mesenchymal stem cell-derived extracellular vesicles alleviate renal fibrosis by reducing epithelial-mesenchymal transition via the FOXS1/Wnt/β-catenin signaling pathway.
Sun J, Jia Y, Chen S, Bian Y, Liang H, Du X
International immunopharmacology 2025 Jan 27;146:113880
International immunopharmacology 2025 Jan 27;146:113880
Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2.
Chen Z, Zhou T, Yin Z, Duan P, Zhang Y, Feng Y, Shi R, Xu Y, Pang R, Tan H
Bone & joint research 2025 Jan 17;14(1):20-32
Bone & joint research 2025 Jan 17;14(1):20-32
SR9009 attenuates TGF-β1-induced renal fibrotic responses by inhibiting the NOX4/p38 signaling pathway in NRK-49F cells.
Takaguri A, Shinohe S, Noro R, Sakuraba M, Satoh C, Ohashi R, Satoh K
European journal of pharmacology 2025 Jan 15;987:177162
European journal of pharmacology 2025 Jan 15;987:177162
Umbilical cord mesenchymal stem cell-derived exosomal Follistatin inhibits fibrosis and promotes muscle regeneration in mice by influencing Smad2 and AKT signaling.
Hu H, Yin Y, Zhou H, Jiang B, Cai T, Wu S, Guo S
Experimental cell research 2025 Jan 15;444(2):114396
Experimental cell research 2025 Jan 15;444(2):114396
Wenshen Xiaozheng Tang alleviates fibrosis in endometriosis by regulating differentiation and paracrine signaling of endometrium-derived mesenchymal stem cells.
Zhang Z, Zhou X, Xia L, Li N, Xu S, Dong X, Zhu L, Huang M, Wan G
Journal of ethnopharmacology 2025 Jan 10;336:118724
Journal of ethnopharmacology 2025 Jan 10;336:118724
Functional Characteristics of the Crosstalk Between Vocal Fold Fibroblasts and Macrophages-The Role of Vibration in Vocal Fold Inflammation.
Steffan B, Grossmann T, Gerstenberger C, Gugatschka M, Hortobagyi D, Kirsch A, Grill M
Journal of voice : official journal of the Voice Foundation 2025 Jan 10;
Journal of voice : official journal of the Voice Foundation 2025 Jan 10;
Injectable agents for the induction of Peyronie's disease in model rats: a comparative study.
Du GJ, Xing SY, Wu N, Wang T, Jiang YH, Song T, Yang BB, Dai YT
Asian journal of andrology 2025 Jan 1;27(1):96-100
Asian journal of andrology 2025 Jan 1;27(1):96-100
Nicotinamide n-methyltransferase inhibitor synergizes with sodium-glucose cotransporter 2 inhibitor to protect renal tubular epithelium in experimental models of type 2 diabetes mellitus.
Yang Y, Li F, Li Y, Li X, Zhao Z, Zhang N, Li H
Journal of diabetes and its complications 2025 Feb;39(2):108952
Journal of diabetes and its complications 2025 Feb;39(2):108952
Acid-Induced in Situ Phase Separation and Percolation for Constructing Bi-Continuous Phase Hydrogel Electrodes With Motion-Insensitive Property.
Han Q, Gao X, Zhang C, Tian Y, Liang S, Li X, Jing Y, Zhang M, Wang A, Bai S
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(6):e2415445
Advanced materials (Deerfield Beach, Fla.) 2025 Feb;37(6):e2415445
α-arbutin prevents UVA-induced skin photodamage via alleviating DNA damage and collagen degradation in NIH-3T3 cells.
Zhao N, Nie X, Yan Y, Liu Z, Chen X, Shu P, Zhong J
Journal of photochemistry and photobiology. B, Biology 2025 Feb;263:113100
Journal of photochemistry and photobiology. B, Biology 2025 Feb;263:113100
Hyperlipidemia impairs bone repair and regeneration via miR-193a-3p/STMN1/PI3K/Akt axis.
Shang J, Li Z, Ma A, Zhu T, Ma G, Gui H, Ren H, Sun B, Wang W, Wang X, Liu C, Li C, Wang Z, Lan J
Biochemical pharmacology 2025 Feb;232:116693
Biochemical pharmacology 2025 Feb;232:116693
Injectable tissue-engineered human cartilage matrix composite fibrin glue for regeneration of articular cartilage defects.
Wang C, Yao H, Shi J, Zhang Z, Cong B, Wu Z, Shang X, Hu X, Yang J, Sun H, Gu Z, Cheng G, Chong H, Wang DA, Zhao Y
Biomaterials advances 2025 Feb;167:214095
Biomaterials advances 2025 Feb;167:214095
Ubiquitin-specific protease 25 improves myocardial ischemia-reperfusion injury by deubiquitinating NLRP3 and negatively regulating NLRP3 inflammasome activity in cardiomyocytes.
Ye B, Xu D, Zhong L, Wang Y, Wang W, Xu H, Han X, Min J, Wu G, Huang W, Liang G
Clinical and translational medicine 2025 Feb;15(2):e70243
Clinical and translational medicine 2025 Feb;15(2):e70243
Engineering Macrophage-Derived Exosome to Deliver Pirfenidone: A Novel Approach to Combat Silicotic Pulmonary Fibrosis.
Chen Z, Yun X, Tian J, Li F, Zhang Z, Meng J, Li N, Bian H, Duan S, Zhang L
Advanced healthcare materials 2025 Feb;14(4):e2403227
Advanced healthcare materials 2025 Feb;14(4):e2403227
Asiatic acid improves the damage of HaCaT cells induced by nitrogen mustard through inhibiting endoplasmic reticulum stress.
Liu H, Cheng J, Ye F, Dong X, Ge W, Wang X, Zhao Y, Dan G, Chen M, Sai Y
Toxicology research 2025 Feb;14(1):tfaf019
Toxicology research 2025 Feb;14(1):tfaf019
A CNA-35-based high-throughput fibrosis assay reveals ORAI1 as a regulator of collagen release from pancreatic stellate cells.
Schleinhege R, Neumann I, Oeckinghaus A, Schwab A, Pethő Z
Matrix biology : journal of the International Society for Matrix Biology 2025 Feb;135:70-86
Matrix biology : journal of the International Society for Matrix Biology 2025 Feb;135:70-86
CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model.
Yang ZC, Lin H, Liu GJ, Pan H, Zhu JL, Zhang XH, Gao F, Wang Z, Wang ZH
Stem cell research & therapy 2025 Feb 7;16(1):52
Stem cell research & therapy 2025 Feb 7;16(1):52
Melatonin alleviates senile osteoporosis by regulating autophagy and enhancing fracture healing in aged mice.
Zhang D, Zhu T, Bai J, Chen C, Wen J, Zhou Y, Guan X
Bone & joint research 2025 Feb 6;14(2):97-110
Bone & joint research 2025 Feb 6;14(2):97-110
Enhancing the Therapeutic Efficacy of Berberine and Quercetin Through Salt Formulation for Liver Fibrosis Treatment.
Cheng Y, Yu H, Yang S, Tian X, Zhao M, Ren L, Guo X, Hu C, Jiang J, Wang L
International journal of molecular sciences 2025 Feb 28;26(5)
International journal of molecular sciences 2025 Feb 28;26(5)
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway.
Dong M, Ma X, Li F
Stem cell research & therapy 2025 Feb 28;16(1):103
Stem cell research & therapy 2025 Feb 28;16(1):103
Ultrasound-guided renal subcapsular transplantation of mesenchymal stem cells for treatment of acute kidney injury in a minipig model: safety and efficacy evaluation.
Xiao T, Chen Y, Jiang B, Huang M, Liang Y, Xu Y, Zheng X, Wang W, Chen X, Cai G
Stem cell research & therapy 2025 Feb 28;16(1):102
Stem cell research & therapy 2025 Feb 28;16(1):102
Huangqi-Danshen decoction alleviates renal fibrosis through targeting SCD1 to modulate cGAS/STING signaling.
Peng Y, Wu S, Xu Y, Ye X, Huang X, Gao L, Lu J, Liu X
Journal of ethnopharmacology 2025 Feb 27;342:119364
Journal of ethnopharmacology 2025 Feb 27;342:119364
Mesoscale orchestration of collagen-based hierarchical mineralization.
Shen M, Zhang C, Zhang Y, Lu D, Yuan J, Wang Z, Wu M, Zhu M, Chen Q
Nature communications 2025 Feb 27;16(1):2041
Nature communications 2025 Feb 27;16(1):2041
MTHFD2 stabilizes LOX expression through RNA methylation modification to promote sepsis-induced acute kidney injury progression.
Sun S, Han B, Ren G, Fan L, Sun J, Li H, Huang J
Human cell 2025 Feb 26;38(2):62
Human cell 2025 Feb 26;38(2):62
Ether bond-modified lipid nanoparticles for enhancing the treatment effect of hepatic fibrosis.
Chu R, Kong J, Gao Q, Yang Y, Pan T, Lu X, Wang Z, Wang Y, He J
International journal of pharmaceutics 2025 Feb 25;671:125192
International journal of pharmaceutics 2025 Feb 25;671:125192
ITIH5-mediated fibroblast/macrophage crosstalk exacerbates cardiac remodelling after myocardial infarction.
Wu Y, Meng L, Zhan S, Li M, Huang J, Chen X, Chen L, Gao X, Chen H, Chen H, Zhong Y, Xu L, Xu Y
Journal of translational medicine 2025 Feb 24;23(1):224
Journal of translational medicine 2025 Feb 24;23(1):224
Drop-shaped microgrooves guide unidirectional cell migration for enhanced endothelialization.
Wang XW, Ye CQ, Tang Q, Yu HM, Wang J, Fu GS, Ren KF, Yu L, Ji J
Nature communications 2025 Feb 24;16(1):1928
Nature communications 2025 Feb 24;16(1):1928
CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis.
Li Z, Jiang J, Cai K, Qiao Y, Zhang X, Wang L, Kang Y, Wu X, Zhao B, Wang X, Zhang T, Lin Z, Wu J, Lu S, Gao H, Jin H, Xu C, Huangfu X, James Z, Chen Q, Zheng X, Liu NN, Zhao J
Bone research 2025 Feb 24;13(1):26
Bone research 2025 Feb 24;13(1):26
Focal Adhesion Regulation as a Strategy against Kidney Fibrosis.
Geng J, Zheng K, Wang P, Su B, Wei Q, Liu X
ACS chemical biology 2025 Feb 21;20(2):464-478
ACS chemical biology 2025 Feb 21;20(2):464-478
Cancer-secreted exosomal miR-1246 promotes colorectal cancer liver metastasis by activating hepatic stellate cells.
Liu X, Liu J, Wang X, Zou Y, Tao X, Li J, Ye M, Xu W, Deng Y, Liu L, Sun J, Zhang Q
Molecular medicine (Cambridge, Mass.) 2025 Feb 20;31(1):68
Molecular medicine (Cambridge, Mass.) 2025 Feb 20;31(1):68
The natural product-derived JM-9 alleviates high-fat diet-induced fatty liver in mice by targeting MD2.
Jin L, Cui Y, Zhang Q, Xiong Y, Zheng X, Ye J, Zhang A, Xiao Z, Zhuang Z, Liang G, Hu X, Luo W, Zhu W
International immunopharmacology 2025 Feb 20;148:114053
International immunopharmacology 2025 Feb 20;148:114053
Growth Differentiation Factor 15 Inhibits Cardiac Fibrosis, Oxidative Stress, Inflammation, and Apoptosis in a Rat Model of Heart Failure with Preserved Ejection Fraction.
Meng X, Li Y, Meng L, Yang C, Xia C, Wang X, Wang F
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
Frontiers in bioscience (Landmark edition) 2025 Feb 18;30(2):26857
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss.
Zhu Q, Wang Y, Xu L, Shi M, Meng Y, Shao C, Lu Y, He Y, Huang J, Li X, Li B, Long Y, Ding Y, Qi J, Wang W, Du Y, Sun Y
The Journal of clinical endocrinology and metabolism 2025 Feb 18;110(3):658-667
The Journal of clinical endocrinology and metabolism 2025 Feb 18;110(3):658-667
Discovery of novel capsaicin analogs as TRPV1 inhibitors for the treatment of idiopathic pulmonary fibrosis.
Cao Y, Wen Y, Zhou Z, Xi R, Shuai W, Zhang J, Suksamrarn A, Zhang G, Lu XX, Wang F
European journal of medicinal chemistry 2025 Feb 15;284:117229
European journal of medicinal chemistry 2025 Feb 15;284:117229
Inhibition of tubular epithelial cells ferroptosis alleviates renal interstitial fibrosis by reducing lipid hydroperoxides and TGF-β/Smad signaling.
Chen Y, Dai Y, Huang Y, Zhang L, Zhang C, Gao H, Yan Q
Cell communication and signaling : CCS 2025 Feb 11;23(1):81
Cell communication and signaling : CCS 2025 Feb 11;23(1):81
Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.
Zhang Y, Tang Z, Chen L, Yang M, Zeng Y, Bai X, Zhang B, Zhou J, Zhang W, Tang S
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Journal of controlled release : official journal of the Controlled Release Society 2025 Feb 10;378:961-981
Recombinant Humanized Collagen Enhances Secreted Protein Levels of Fibroblasts and Facilitates Rats' Skin Basement Membrane Reinforcement.
Ye S, Chen B, Jeevithan L, Yang H, Kong Y, Diao X, Wu W
Journal of functional biomaterials 2025 Feb 1;16(2)
Journal of functional biomaterials 2025 Feb 1;16(2)
Plasma-activated solutions prevent peritoneal adhesion formation by regulating eNOS expression in mesothelial cells.
Ma Y, Sun T, Ren K, Ma R, Min T, Wang X, Yuan Y, Xie X, Zhang B, Deng X, Peng Y, Liu Y, Nan Y, Wang W, Zhou Z, Xu G, Li K, Zhu K, Hao N, Dang C, Zhang G, Zhang H
Journal of advanced research 2025 Dec;78:555-571
Journal of advanced research 2025 Dec;78:555-571
SPP1-mediated crosstalk between macrophage and fibroblasts promotes benign airway stenosis.
Niu F, Sun B, Yu Y, Xu X, Li H, Huang L, Wang Y, Cai Z
Archives of biochemistry and biophysics 2025 Dec;774:110627
Archives of biochemistry and biophysics 2025 Dec;774:110627
An Electrospun Heparin Modified Nanofiber Membrane Carrying Multiple Growth Factors for Dental Pulp Regeneration.
Li XL, Liu H, Fan W, Fan B
International dental journal 2025 Dec;75(6):103919
International dental journal 2025 Dec;75(6):103919
Uncovering the mechanistic basis of Rheum palmatum L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular docking, and experimental validation.
He W, Wei Z, Li S, Han S, Ma J, Wu L, Lu D, Ta G
Pharmaceutical biology 2025 Dec;63(1):582-606
Pharmaceutical biology 2025 Dec;63(1):582-606
Nano MgO loaded thermosensitive HPCH@HA hydrogel accelerates in situ bone repair through osteoimmunomodulation while enhancing angiogenesis and osteogenesis.
Ni F, Chang L, Peng Y, Li D, Wu D, Li K, Zhang X, Jiang X, Shao Z, Chen Y, Wang H
Bioactive materials 2025 Dec;54:248-272
Bioactive materials 2025 Dec;54:248-272
Concentrated Micronized Fat Ameliorates Skin Fibrosis in Bleomycin-Induced Murine Model and Enhances Fat Graft Survival.
Ma X, Dong M, Yin N, Li F
Aesthetic plastic surgery 2025 Dec;49(24):6942-6953
Aesthetic plastic surgery 2025 Dec;49(24):6942-6953
Mulberry-derived carbon dots attenuate kidney fibrosis through direct inhibition of PI3K.
Liu T, Wu Y, Wang C, Zhou T, Yang R, Zhang X, Yan W, Fan Q, Lu Z
Materials today. Bio 2025 Dec;35:102626
Materials today. Bio 2025 Dec;35:102626
3D printing combined with thermally induced phase separation for engineering hierarchical osteogenic PLA scaffolds.
Yun X, Li Z, Yan Z, Li S, Dai Z, Hu J, Ren Y, Huang L, Wang Q, Zhang C, Li J, Deng C, Liu H, Zheng W, Zhong C, Zhang Z
Materials today. Bio 2025 Dec;35:102621
Materials today. Bio 2025 Dec;35:102621
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
Zhang A, Liu Z, Zou L, Yang L, Wu Y, Wang X, Cao D, Liu J, Yang X, Zhang S
Materials today. Bio 2025 Dec;35:102308
Materials today. Bio 2025 Dec;35:102308
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Kong C, Si C, Liu H, Wang Y, Qiao J, Tang X, Sun H, Zhang J, Chang B
Materials today. Bio 2025 Dec;35:102295
Materials today. Bio 2025 Dec;35:102295
STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.
Qian L, Deng S, Tian T, He Y, Li Y, Wang X, Tian T, Jiang M, Pan Y, Li D
Experimental dermatology 2025 Dec;34(12):e70193
Experimental dermatology 2025 Dec;34(12):e70193
Aldehyde Dehydrogenase 6 Family Member A1 Facilitates Ti Implant Osseointegration in Hyperlipidemia.
Wang YN, Yu L, Liu Y, Xu X, Zhang D, Liu S, Ge S
Oral diseases 2025 Dec;31(12):3437-3449
Oral diseases 2025 Dec;31(12):3437-3449
Hypericin-mediated photodynamic therapy promotes apoptosis and inhibits fibrosis by inducing HMOX1-mediated ferroptosis in hypertrophic scar fibroblasts.
Li X, Chen Z, Liu M, An J, Shang J, Zhu G, Wen H, Guo G
Journal of photochemistry and photobiology. B, Biology 2025 Dec;273:113303
Journal of photochemistry and photobiology. B, Biology 2025 Dec;273:113303
Asiatic acid inhibits endothelial-to-mesenchymal transition in diabetic kidney disease by reducing acetyl-CoA production via targeting ACSS2.
Lin RH, Chen JC, Xu SS, Xu YY, Pan K, Wang L, Zhang J, Yin ZQ, Huang YP
Biochemical pharmacology 2025 Dec;242(Pt 2):117311
Biochemical pharmacology 2025 Dec;242(Pt 2):117311
Stellarin I: A Bioactive Cyclic Nonapeptide with Potent Anti-renal Fibrosis Activity from the Root of Stellaria yunnanensis Franch.
Deng R, Gu C, Wang J, Li X, Xin X, Yang Y, Li J, Xia C, An F
Chemistry & biodiversity 2025 Dec;22(12):e02177
Chemistry & biodiversity 2025 Dec;22(12):e02177
Myofibroblast specific knockdown of NSUN2 suppresses cardiac fibrosis post-myocardial infarction.
Sun Z, Li N, Huang M, Li Y, Wang C, Qu Z, Yu S, Mei Z, Wu B, Dou S, Jiang J, Zhang Y, Huang C, Han J, Yue Y, Li X, Dong Y, Du W
Journal of molecular and cellular cardiology 2025 Dec;209:27-36
Journal of molecular and cellular cardiology 2025 Dec;209:27-36
LIPUS promotes osteogenesis via the mcirc_9393-miR-217/326-SIRT1 axis in porous Ti6Al4V scaffolds.
Cao H, Yu Y, Wu L, Hao F
Bone 2025 Dec;201:117647
Bone 2025 Dec;201:117647
Docking and database screening identify manidipine as a potential modulator of matrix metalloproteinase-7 in chronic kidney disease.
Liao CT, Lin YC, Huang HJ, Liu WC, Kan WC, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Dec;193:118748
5'tiRNA-Glu-TTC targets TRPV3 and activates the PI3K/AKT signaling pathway to modulate skin photoaging.
Xu Z, Liu L, Dai X, Zhou X, Chen L, Chen H, Luan C, Huang D, Zhang J, Hu Y, Chen K, Gu H
Non-coding RNA research 2025 Dec;15:29-43
Non-coding RNA research 2025 Dec;15:29-43
Bmi-1 overexpression mitigates vitamin D deficiency-induced pulmonary fibrosis via TIME pathway.
Zhang J, Huang M, Zhou J, Chen H, Wang Z, Jin J, Shu L, Miao D
Cellular signalling 2025 Dec;136:112180
Cellular signalling 2025 Dec;136:112180
HMGB1-enhanced autophagic degradation of E-cadherin facilitates mesothelial trans-differentiation and postoperative peritoneal adhesion.
Yuan X, Yang S, Qu C, Zhang R, Ren Y, Sun Y, Li E, Li G, Zhang J, Du J, Shen T, Jiang Z, Li X
BMC gastroenterology 2025 Dec 30;26(1):83
BMC gastroenterology 2025 Dec 30;26(1):83
Cx43 hemichannel-mediated paracrine involves in the promotion of MSCs on skin wound healing.
Dou X, Zhang Y, Yang X, Niu Y, Wang DE, Xu H
Stem cell research & therapy 2025 Dec 3;16(1):672
Stem cell research & therapy 2025 Dec 3;16(1):672
Dual-functional nanovesicles simultaneously inhibit stromal fibrosis and angiogenesis to suppress cholangiocarcinoma progression.
Zhang L, Duan X, Shi Q, Yao X, Chen Q, Wan J, Wang F, Ni C, Li Y, Wang M, Sheng Y, Zheng W, Liu J, Ji T, Qin Z
Journal of nanobiotechnology 2025 Dec 22;23(1):781
Journal of nanobiotechnology 2025 Dec 22;23(1):781
Enhancement of drug delivery through fibroblast activation protein-targeted near-infrared photoimmunotherapy.
Nishimura S, Noma K, Matsumoto T, Takeda Y, Takahashi T, Matsumoto H, Kawasaki K, Kawai H, Kunitomo T, Akai M, Kobayashi T, Nishiwaki N, Kashima H, Kato T, Kikuchi S, Tanabe S, Ohara T, Tazawa H, Shirakawa Y, Choyke PL, Kobayashi H, Fujiwara T
JCI insight 2025 Dec 22;10(24)
JCI insight 2025 Dec 22;10(24)
Fibrotic collagen-targeted delivery system blocks pancreatic intercellular crosstalk to alleviate pancreatic fibrosis.
Wang H, Qi L, Fang YF, Liu Y, Ye Z, Chen BT, Wang Y, Jiang HL, Li L
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114278
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114278
Procyanidin B2 mitigate asthmatic airway remodeling by inhibiting TGF-β1-induced airway smooth muscle proliferation through ROS signaling.
Liang W, Zhang M, Wang H, Feng L, Li D, Hao R, Xie W, Zeng X, Ma Y
Tissue & cell 2025 Aug;95:102863
Tissue & cell 2025 Aug;95:102863
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.
Kuang B, Geng N, Yi M, Zeng Q, Fan M, Xian M, Deng L, Chen C, Pan Y, Kuang L, Luo F, Xie Y, Liu C, Deng Z, Nie M, Du Y, Guo F
Journal of advanced research 2025 Aug;74:493-511
Journal of advanced research 2025 Aug;74:493-511
Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment.
Yu B, Peng L, Dang W, Fu Y, Li Z, Feng J, Zhao H, Wang T, Xu F, Yarmush ML, Huang H
Bioactive materials 2025 Aug;50:461-474
Bioactive materials 2025 Aug;50:461-474
TGF-β drives myofibroblast activation and inflammatory mediator production in vulvar lichen sclerosus.
Fischer SA, Mahamed Z, Updike A, Boachie B, Greene C, Agwaze R, Parr K, Love T, Bonham AD, Linder MA, Falsetta ML
AJOG global reports 2025 Aug;5(3):100528
AJOG global reports 2025 Aug;5(3):100528
Inhibition of GDNF-Driven Macrophage-to-Myofibroblast Transition Protects Against Colitis-Associated Intestinal Fibrosis.
Zeng J, Du XL, Lu QQ, Chen WQ, Yang XJ
Inflammation 2025 Aug;48(4):2069-2077
Inflammation 2025 Aug;48(4):2069-2077
Adhesive hydrogel based on Konjac Glucomannan (KGM) loaded with siACTC1-exosomes for enhanced post-surgical keloid treatment.
Zhong Y, Zhang Y, Liu Y, Zeng K, Fan L, Wang Q, Zhang J
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
International journal of biological macromolecules 2025 Aug;319(Pt 3):145360
Polo-like kinase 1 drives hypoxia-induced renal fibrosis via PTEN/PGK1-mediated glycolytic activation.
Jiang A, Chen S, Yu X, Jia Y, Sun J, Bian Y, Du X, Gu X
International journal of biological macromolecules 2025 Aug;319(Pt 1):145305
International journal of biological macromolecules 2025 Aug;319(Pt 1):145305
Silencing PIM1 inhibits ENO1-induced AKT activation and attenuates fibrillogenesis during spinal cord injury-induced skeletal muscle atrophy.
Yu X, Cao J, Wang B, Fu J, Liu J, Sui T, Wang Z, Wu C, Chang J, Cao X, Zhang S
The Journal of biological chemistry 2025 Aug;301(8):110398
The Journal of biological chemistry 2025 Aug;301(8):110398
From stem cells to skin: ADSCP6 peptide's role in transforming scar therapy.
Li J, Zeng S, Zhou B, Yan Q, Sun Y, Chen L, Zhang E, Li J
Biochemical pharmacology 2025 Aug;238:116980
Biochemical pharmacology 2025 Aug;238:116980
Molten-Salt-Mediated Synthesis of Atomic Manganese/Cobalt Catalysts on Bioceramic Microparticles for Catalytic Anti-Osteoarthritis Treatments.
Deng R, Zhang Z, Wu A, Shu C, Song S, Yuan F, Xu Z, Yang M, Ye J, Song Y, Zhu Y, Yu JK
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e05500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e05500
Butyrate protects against myocardial ischemia injury and cardiomyocyte pyroptosis by inhibiting MALT1-mediated Nrf2 ubiquitination and degradation.
Zhang P, Su Y, Cheng Y
Journal of molecular histology 2025 Aug 8;56(4):261
Journal of molecular histology 2025 Aug 8;56(4):261
Paclitaxel-mediated microtubule stabilization regulates flexor tendon repair in rats.
Yang JJ, Xu SW, Zhang XY, Mao WF, Wu YF
Bone & joint research 2025 Aug 6;14(8):685-695
Bone & joint research 2025 Aug 6;14(8):685-695
Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus.
Zhang H, Yang H, Wu Y, Shi Y, Xu M, Zhang Y, Chen H, Sun L
Lupus science & medicine 2025 Aug 5;12(2)
Lupus science & medicine 2025 Aug 5;12(2)
Rehmannioside A alleviates renal inflammation and fibrosis in hypertensive nephropathy via AT1R/MAPK14/IL-17 signaling pathway.
Liu F, Wang J, Sun Z, Yu X
Biochemical and biophysical research communications 2025 Aug 30;776:152237
Biochemical and biophysical research communications 2025 Aug 30;776:152237
Maimendong decoction and its active ingredient, ophiopogonin D, alleviate bleomycin-induced pulmonary fibrosis by regulating the behavior of lung fibroblasts.
Yang M, Zhang X, Bao S, Yang S, Zhang Y, Liu Y, Li C, Zou J, Li J, Yan S
Chinese medicine 2025 Aug 29;20(1):135
Chinese medicine 2025 Aug 29;20(1):135
Low-protein Calorie-restriction Mitigates Diabetic Mice Kidney Injury via the Gut-Kidney Axis.
Zhang R, Wei X, Xu Y, Han C, Cai X, Wu Y, Geng Y, Liu C
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2025 Aug 27;95(4):37311
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2025 Aug 27;95(4):37311
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Cui Z, Gu G, Chen F, Li J, Du X, Chen S, Zhang H, Li C, Shao J, Xi J, Du Y, Zhao Q, Xi Y
Cell death & disease 2025 Aug 27;16(1):651
Cell death & disease 2025 Aug 27;16(1):651
MSC-derived exosomes improve endometrial fibrosis via the lncRNA IGF2R/ miR-143-5p/AQP8 axis.
Huo X, Chen J, Qian M, Xue Q, Xu P, Wang Y, Jiang Z, Luo Q, Xiong Y
Stem cell research & therapy 2025 Aug 27;16(1):464
Stem cell research & therapy 2025 Aug 27;16(1):464
Lysionotin attenuates bleomycin-induced pulmonary fibrosis by activating AMPK/Nrf2 pathway.
Zhang X, Xiong D, Deng L, Qian R, Tang S, Liu W, Li Y, Liu L, Xie W, Lin M
Scientific reports 2025 Aug 25;15(1):31306
Scientific reports 2025 Aug 25;15(1):31306
[Haematococcus pluvialis alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting transformation of lung fibroblasts into myofibroblast].
Zhang X, Man J, Zhang Y, Zheng Y, Wang H, Yuan Y, Xie X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Aug 20;45(8):1672-1681
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
Qiao G, Li C, Wang M, Zhang W, Shi J, Meng B, Zhang L, Zhang R, Qi H, Xin S
BMC gastroenterology 2025 Aug 20;25(1):605
BMC gastroenterology 2025 Aug 20;25(1):605
Eupatorium lindleyanum DC Ameliorates Carbon Tetrachloride-Induced Hepatic Inflammation and Fibrotic Response in Mice.
Yang J, Wang Y, Zhuo L, Lu G, Zhang M, Huang J, Li Y, Liu W, Qi J, Zhu A, Zhou Z
Pharmaceuticals (Basel, Switzerland) 2025 Aug 20;18(8)
Pharmaceuticals (Basel, Switzerland) 2025 Aug 20;18(8)
The protective role of ureteral stents in reducing fibrosis and preventing stricture in ureteral injuries of different severities.
Gu H, Yang T, Qin Z, Zhang S, Wang L, Zhao Z
BMC urology 2025 Aug 19;25(1):204
BMC urology 2025 Aug 19;25(1):204
NAT10 Mediates Cardiac Fibrosis Induced by Myocardial Infarction Through ac4C Modification of TGFBR1 mRNA.
Zhou J, Chen Y, Chen J, Xia G, Zeng J, Wang L
Cell biology and toxicology 2025 Aug 12;41(1):125
Cell biology and toxicology 2025 Aug 12;41(1):125
Ergosterol from edible fungi: Enhancing fatty acid oxidation via CPT1A to protect against diabetic kidney disease.
Dong Z, Li X, Wang X, Xu J, Xu W
Food & function 2025 Aug 11;16(16):6599-6611
Food & function 2025 Aug 11;16(16):6599-6611
Targeted Delivery of CD34 Aptamer-Coupled Tocilizumab Microspheres for Effective Treatment of Thyroid-Associated Ophthalmopathy.
Luo Y, Yin J, Cao J, Xie B, Zhang F, Ouyang S, Zhou J, Tan Y, Xiong W
Investigative ophthalmology & visual science 2025 Aug 1;66(11):57
Investigative ophthalmology & visual science 2025 Aug 1;66(11):57
The Role of Luteolin in Inhibiting Prostaglandin-Endoperoxide Synthase 2 to Relieve Neointimal Hyperplasia in Arteriovenous Fistula.
Zhang R, Li W, Yang J, Fan X, Fan H, Li W
Advanced biology 2025 Apr;9(4):e2400437
Advanced biology 2025 Apr;9(4):e2400437
Tanshinone IIA alleviates pulmonary fibrosis by modulating glutamine metabolic reprogramming based on [U-(13)C(5)]-glutamine metabolic flux analysis.
Shan B, Guo C, Zhou H, Chen J
Journal of advanced research 2025 Apr;70:531-544
Journal of advanced research 2025 Apr;70:531-544
Thymoquinone mitigates cardiac hypertrophy by activating adaptive autophagy via the PPAR‑γ/14‑3‑3γ pathway.
Qiu RB, Zhao ST, Xu ZQ, Hu LJ, Zeng RY, Qiu ZC, Peng HZ, Zhou LF, Cao YP, Wan L
International journal of molecular medicine 2025 Apr;55(4)
International journal of molecular medicine 2025 Apr;55(4)
Nrf2 deficiency aggravates hepatic cadmium accumulation, inflammatory response and subsequent injury induced by chronic cadmium exposure in mice.
Chen C, Han X, Xu N, Shen W, Wang G, Jiao J, Kong W, Yu J, Fu J, Pi J
Toxicology and applied pharmacology 2025 Apr;497:117263
Toxicology and applied pharmacology 2025 Apr;497:117263
Circadian clock gene BMAL1 is involved in transforming growth factor β1-induced fibrotic response in NRK-49F cells.
Takaguri A, Noro R, Shinohe S, Murayama R, Sakuraba M, Nomura R, Satoh K
Cell biology international 2025 Apr;49(4):365-373
Cell biology international 2025 Apr;49(4):365-373
Synergizing adaptive immunity and regenerative signals to enhance osteochondral defects repair.
Lin C, Ying C, Xu Y, Zou Y, Chen R, Xu K, Ji X, Cao Q, Weng J, Jiang L, Ye C, Xu K, He Y, Li W, Wu L, Ran J, Xiong Y, Yu X, Bao J
Bioactive materials 2025 Apr;46:242-258
Bioactive materials 2025 Apr;46:242-258
Engineered Stem Cell Booster Breaks Pathological Barriers to Treat Chronic Pancreatitis.
Han H, Chen BT, Liu Y, Qi L, Xing L, Wang H, Zhao M, Zhang C, Yu P, Wei N, Wang J, Zhou F, Wang GJ, Cheng XW, Huang ZJ, Li L, Jiang HL
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(14):e2416261
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(14):e2416261
Engineered MSCs Break Endothelial-Myofibroblast Crosstalk in Pulmonary Fibrosis: Reconstructing the Vascular Niche.
Fang YF, Zhang C, Han MM, Wang Y, Zhou TJ, Xing L, Wei N, Wang J, Jeong JH, Zhou F, Wang GJ, Jiang HL
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(13):e2414601
Advanced materials (Deerfield Beach, Fla.) 2025 Apr;37(13):e2414601
BMAL1 Regulates Collagen Production in the Myometrium and Leiomyomas.
Dai Y, Ono M, Suzuki T, Hayashi S, Kojima J, Sasaki T, Fujiwara T, Daikoku T, Terakawa J, Maida Y, Ando H, Fujiwara H, Kuji N, Nishi H
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1115-1128
Reproductive sciences (Thousand Oaks, Calif.) 2025 Apr;32(4):1115-1128
3D bioprinted piezoelectric hydrogel synergized with LIPUS to promote bone regeneration.
Li M, Hu X, Liu X, Zhao L, Zhao W, Li Y, Bie X, Jiao H, Zhao Y, Ma C
Materials today. Bio 2025 Apr;31:101604
Materials today. Bio 2025 Apr;31:101604
Hydrogel inspired by "adobe" with antibacterial and antioxidant properties for diabetic wound healing.
Li Z, Chen R, Hao Z, E Y, Guo Q, Li J, Zhu S
Materials today. Bio 2025 Apr;31:101477
Materials today. Bio 2025 Apr;31:101477
A nanoemulgel formulation of acetylated Crataegus pinnatifida polysaccharide for the treatment of skin photoaging in mice.
Ain NU, Akhlaq MH, Zhu K, Ji W, Yi L, Li D, Zhang Z
International journal of biological macromolecules 2025 Apr;303:140649
International journal of biological macromolecules 2025 Apr;303:140649
Hepatoprotective effects of polysaccharide from Morchella esculenta are associated with activation of the AMPK/Sirt1 signaling pathway in mice with NAFLD.
Wang D, Zhang M, Zhang Y, Yin Z, Zhang S, Zhao Z, Duan Y
International journal of biological macromolecules 2025 Apr;301:140444
International journal of biological macromolecules 2025 Apr;301:140444
circSIRT2/miR-542-3p/VASH1 axis regulates endothelial-to-mesenchymal transition (EndMT) in subretinal fibrosis in age-related macular degeneration models.
Zhang M, Wu J, Wang Y, Wu Y, Wan X, Jiang M, Bo Q, Chen J, Sun X
Aging cell 2025 Apr;24(4):e14443
Aging cell 2025 Apr;24(4):e14443
Tamibarotene directly targets the NACHT domain of NLRP3 to alleviate acute myocardial infarction.
Chen X, Wang Y, Huang J, Dou H, Zhang Z, Zheng Y, Long R, Zhang X, Xu F, Ye W, Xiao Q
Biochemical pharmacology 2025 Apr;234:116801
Biochemical pharmacology 2025 Apr;234:116801
Impact of red-lime and white-lime betel quid on oral cell lines: Cytotoxicity and effects on fibronectin and type I collagen expression.
Wu CC, Kao YH, Kim YD, Ting CC, Chen H, Wu FC, Miura K, Ogasawara T, Hoshi K, Lo WL, Chen YC, Jeng JH, Ko EC
Journal of dental sciences 2025 Apr;20(2):819-829
Journal of dental sciences 2025 Apr;20(2):819-829
Hypoxia amplifies arecoline-induced invasion and metastasis in oral squamous cell carcinoma - Insights into TGF-β1 signaling and collagen production.
Wu FC, Ting CC, Jeng JH, Chen H, Kim YD, Wu CC, Kao YH, Tseng CH, Chen YK, Ogasawara T, Hoshi K, Lo WL, Takahashi T, Yang YH, Ko EC
Journal of dental sciences 2025 Apr;20(2):1129-1138
Journal of dental sciences 2025 Apr;20(2):1129-1138
Metformin Alleviates Fibrosis of Trabecular Meshwork Cells Induced by TGFβ2 Through the Activation of Autophagy.
Ren J, Wu P, Liu M, Zhang X, Guo Z, Liu Y, Zhao R, Wang G, Duan S, Li H
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
Dose-response : a publication of International Hormesis Society 2025 Apr-Jun;23(2):15593258251341598
Chrysophanol Attenuates Cardiac Fibrosis and Arrhythmia by Suppressing the Endoplasmic Reticulum Stress/Pyroptosis Axis and Inflammation.
Liu C, Qiu S, Liu X, Huang R, Fang Z
Phytotherapy research : PTR 2025 Apr 5;
Phytotherapy research : PTR 2025 Apr 5;
A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells.
Lee SY, Jang Y, Seok HY, Moon YH
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70541
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70541
Exercise-Mediated Mechanical Stress Promotes Osteogenic Differentiation of BMSCs Through Upregulation of Lactylation via the IER3/LDHB Axis.
Dai S, Chen Z, Liu X, Dong J, Zhang Z, Yang Z, Huang M, Cai L, Xiao X, Zhu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70537
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70537
Fullerol Initiates Stem Cell-Nanomaterials Interactions for Enhanced Tissue Regeneration via Clathrin-Mediated Endocytosis and Nuclear Factor Erythroid 2-Related Factor 2 Signaling.
Liu H, Zhu Y, Chen W, Sheng R, Liu C, Sun Y, Liu J, Wang M, Lu J, Chen J, Zhang W
ACS applied materials & interfaces 2025 Apr 30;17(17):25011-25034
ACS applied materials & interfaces 2025 Apr 30;17(17):25011-25034
OTUD1 inhibits endometriosis fibrosis by deubiquitinating MADH7.
Chang X, Zhang Y, Deng M, Yang R, Zhang J, Hao M, Miao J
Molecular human reproduction 2025 Apr 3;31(2)
Molecular human reproduction 2025 Apr 3;31(2)
Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration.
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F
RSC advances 2025 Apr 28;15(18):13857-13873
RSC advances 2025 Apr 28;15(18):13857-13873
LncRNA MRF targeting FSHR inhibits the osteogenic differentiation of BMSCs and bone defect repair through the regulation of the cAMP-PKA-CREB signaling pathway.
Ning Q, Li M, Liao Z, Chen E, Liu H, Liang Y, Chen Y, Li Y, Huang L
Stem cell research & therapy 2025 Apr 23;16(1):200
Stem cell research & therapy 2025 Apr 23;16(1):200
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF.
Zhou W, Wang J, Ding L, Cai R, Cheng J, Liang P, Zhu Y, Zhang Z
Scientific reports 2025 Apr 21;15(1):13805
Scientific reports 2025 Apr 21;15(1):13805
Dehydrocorydaline attenuates bleomycin-induced pulmonary fibrosis by inhibiting fibroblast activation.
He J, Yue H, Zhang S, Dong R, Zhang F, Wang X, Wang K, Zhang H, Yang D, Dong Z, Liu H
Respiratory research 2025 Apr 12;26(1):136
Respiratory research 2025 Apr 12;26(1):136
Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation.
Ni X, Wei Z, Peng Y, Zheng L, Shang J, Liu F, Li Y, Liu J
Ecotoxicology and environmental safety 2025 Apr 1;294:118113
Ecotoxicology and environmental safety 2025 Apr 1;294:118113
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Xiao Y, He Y, Zhong D, Liu B, Tang Z, Lan X, Dong Y, Du H, Liu Y, Luo J
ACS nano 2025 Apr 1;19(12):11841-11860
ACS nano 2025 Apr 1;19(12):11841-11860
Effects of Different Light Environments with Varying Spectral Composition on the Axial Lengths and Scleral Specificity Protein 1 and Collagen Type I Expression in Juvenile Guinea Pigs.
Yuan J, Wang Y, Xu X, Yang M, Fan Y, Shi X, Sun L, Shan M, Ma L
Folia biologica 2024;70(4):219-228
Folia biologica 2024;70(4):219-228
An Integrated Dual-Layer Heterogeneous Polycaprolactone Scaffold Promotes Oral Mucosal Wound Healing through Inhibiting Bacterial Adhesion and Mediating HGF-1 Behavior.
Hong G, Hu Z, Zhou Y, Chen M, Wu H, Lu W, Jin W, Yao K, Xie Z, Shi J
Research (Washington, D.C.) 2024;7:0499
Research (Washington, D.C.) 2024;7:0499
Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop.
Zhang X, Wang J, Xiang S, Zhao L, Lv M, Duan Y, Gao G, Wang P, Jie Chen J, Xu J, Xie Z, Zhang Z
The American journal of Chinese medicine 2024;52(6):1795-1817
The American journal of Chinese medicine 2024;52(6):1795-1817
Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.
Liu X, Zhao W, Hu M, Zhang Y, Wang J, Zhang L
Iranian journal of basic medical sciences 2024;27(5):588-595
Iranian journal of basic medical sciences 2024;27(5):588-595
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin.
Zhang C, Wang WS, Yao G, Zhu Y, Lin Y, Lu J, Sun K, Sun Y
Human reproduction open 2024;2024(1):hoae002
Human reproduction open 2024;2024(1):hoae002
Comparative Analysis of the Therapeutic Effects of MSCs From Umbilical Cord, Bone Marrow, and Adipose Tissue and Investigating the Impact of Oxidized RNA on Radiation-Induced Lung Injury.
Zhai R, Tai F, Ding K, Tan X, Li H, Cao Z, Ge C, Zheng X, Fu H
Stem cells international 2024;2024:7419270
Stem cells international 2024;2024:7419270
Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF-β/Smad Signaling Pathway.
Xu G, Ma T, Zhou C, Zhao F, Peng K, Li B
Analytical cellular pathology (Amsterdam) 2024;2024:2751280
Analytical cellular pathology (Amsterdam) 2024;2024:2751280
Lysozyme promotes renal fibrosis through the JAK/STAT3 signal pathway in diabetic nephropathy.
Ren Y, Yu M, Zheng D, He W, Jin J
Archives of medical science : AMS 2024;20(1):233-247
Archives of medical science : AMS 2024;20(1):233-247
Swimming alleviates myocardial fibrosis of type II diabetic rats through activating miR-34a-mediated SIRT1/PGC-1α/FNDC5 signal pathway.
Guo Y, Zhou F, Fan J, Wu T, Jia S, Li J, Chen N
PloS one 2024;19(9):e0310136
PloS one 2024;19(9):e0310136
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Wang Y, Deng X, Wei J, Yang Z, Du Y, Song S, Shi Y, Wu H
PloS one 2024;19(6):e0299389
PloS one 2024;19(6):e0299389
SIRT3 regulates cardiolipin biosynthesis in pressure overload-induced cardiac remodeling by PPARγ-mediated mechanism.
Liu LX, Zheng XH, Hai JH, Zhang CM, Ti Y, Chen TS, Bu PL
PloS one 2024;19(4):e0301990
PloS one 2024;19(4):e0301990
TAK-242 alleviates diabetic cardiomyopathy via inhibiting pyroptosis and TLR4/CaMKII/NLRP3 pathway.
Zhao X, Zhang J, Xu F, Shang L, Liu Q, Shen C
Open life sciences 2024;19(1):20220957
Open life sciences 2024;19(1):20220957
Liposomes Loaded with 5-Fluorouracil Can Improve the Efficacy in Pathological Scars.
Li Y, Sun Q, Hao L, Shan H, Jiang Z, Wang Y, Chen Z, Zhu W, Zhao S
International journal of nanomedicine 2024;19:7353-7365
International journal of nanomedicine 2024;19:7353-7365
A TSHR-Targeting Aptamer in Monocytes Correlating with Clinical Activity in TAO.
Cao J, Zhang F, Chen H, Wu B, Yin J, Chenzhao C, Xiong W
International journal of nanomedicine 2024;19:3577-3588
International journal of nanomedicine 2024;19:3577-3588
Pretreatment of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes with Quercetin Enhances the Healing of Diabetic Skin Wounds by Modulating Host-Microbiota Interactions.
Wu S, Zhou Z, Li Y, Wu R, Jiang J
International journal of nanomedicine 2024;19:12557-12581
International journal of nanomedicine 2024;19:12557-12581
Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway.
Wang D, Wang J, Yin Z, Gong K, Zhang S, Zha Z, Duan Y
International journal of nanomedicine 2024;19:10839-10856
International journal of nanomedicine 2024;19:10839-10856
Graphene Oxide Quantum Dots-Preactivated Dental Pulp Stem Cells/GelMA Facilitates Mitophagy-Regulated Bone Regeneration.
Yan X, An N, Zhang Z, Qiu Q, Yang D, Wei P, Zhang X, Qiu L, Guo J
International journal of nanomedicine 2024;19:10107-10128
International journal of nanomedicine 2024;19:10107-10128
Catalpol Enhances Osteogenic Differentiation of Human Periodontal Stem Cells and Modulates Periodontal Tissue Remodeling in an Orthodontic Tooth Movement Rat Model.
Hu J, Song Y, Zhang Y, Yang P, Chen S, Wu Z, Zhang J
Drug design, development and therapy 2024;18:4943-4960
Drug design, development and therapy 2024;18:4943-4960
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Guo C, Jiao M, Cui Y, Li P, Yao J, Dong J, Liao L
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Qizhu Rougan Granules suppress liver fibrosis by inhibiting the expression of the P2Y14 receptor on hepatic stellate cells.
Tao Y, Niu Q, Yao Y, Wang K, Dong H, Zhao X, Zeng Z, Li H
Frontiers in pharmacology 2024;15:1528100
Frontiers in pharmacology 2024;15:1528100
Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway.
Liu S, Cao Y, Yuan Q, Xie Y, Zhu Y, Yao L, Zhang C
Frontiers in pharmacology 2024;15:1510098
Frontiers in pharmacology 2024;15:1510098
Licoricesaponin G2 ameliorates bleomycin-induced pulmonary fibrosis via targeting TNF-α signaling pathway and inhibiting the epithelial-mesenchymal transition.
Ma J, Ding L, Zang X, Wei R, Yang Y, Zhang W, Su H, Li X, Li M, Sun J, Zhang Z, Wang Z, Zhao D, Li X, Zhao L, Tong X
Frontiers in pharmacology 2024;15:1437231
Frontiers in pharmacology 2024;15:1437231
RMRP accelerates ligamentum flavum hypertrophy by regulating GSDMD-mediated pyroptosis through Gli1 SUMOylation.
Yan X, Liu T, Zhang R, Ma Q, Sun C
Frontiers in immunology 2024;15:1427970
Frontiers in immunology 2024;15:1427970
Deciphering m(6)A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy.
Li J, Wei L, Hu K, He Y, Gong G, Liu Q, Zhang Y, Zhou K, Guo J, Hua Y, Tang J, Li Y
Theranostics 2024;14(9):3486-3508
Theranostics 2024;14(9):3486-3508
Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.
Shao M, Cheng H, Li X, Qiu Y, Zhang Y, Chang Y, Fu J, Shen M, Xu X, Feng D, Han Y, Yue S, Zhou Y, Luo Z
Theranostics 2024;14(7):2687-2705
Theranostics 2024;14(7):2687-2705
Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts.
Zhou ZY, Song K, Liu ZY, Ke YF, Shi Y, Cai K, Zhao R, Sun X, Tao H, Zhao JY
Theranostics 2024;14(19):7333-7348
Theranostics 2024;14(19):7333-7348
Activating autophagy promotes skin regeneration induced by mechanical stretch during tissue expansion.
Du J, Liu W, Song Y, Zhang Y, Dong C, Xiong S, Huang Z, Wang T, Ding J, He Q, Yu Z, Ma X
Burns & trauma 2024;12:tkad057
Burns & trauma 2024;12:tkad057
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
Dai S, Xu M, Pang Q, Sun J, Lin X, Chu X, Guo C, Xu J
Burns & trauma 2024;12:tkad036
Burns & trauma 2024;12:tkad036
Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction.
Ni J, Zhang X, Huang H, Ni Z, Luo J, Zhong Y, Hui M, Liu Z, Qian J, Zhang Q
PeerJ 2024;12:e17009
PeerJ 2024;12:e17009
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
Ding S, Jiang J, Li Y
PeerJ 2024;12:e16703
PeerJ 2024;12:e16703
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Zhao L, Zhang J, Song Q, Dai C, Qin Y, Li A
Frontiers in cell and developmental biology 2024;12:1516898
Frontiers in cell and developmental biology 2024;12:1516898
Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.
Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X
Frontiers in cell and developmental biology 2024;12:1376814
Frontiers in cell and developmental biology 2024;12:1376814
Recombinant humanized type I collagen remodels decidual immune microenvironment at maternal-fetal interface by modulating Th17/Treg imbalance.
Wang L, Zeng H, Li H, Dai J, You S, Jiang H, Wei Q, Dong Z, Liu S, Ren J, Zhu Y, Yang X, He F, Hu L
International journal of biological macromolecules 2024 Sep;276(Pt 2):133994
International journal of biological macromolecules 2024 Sep;276(Pt 2):133994
Counteracting TGM2 by a Fibroin peptide ameliorated Adriamycin-induced nephropathy via regulation of lipid metabolism through PANX1-PPAR α/PANK1 pathway.
Li SS, Liu QJ, Bao JX, Lu MT, Deng BQ, Li WW, Cao CC
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:26-39
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:26-39
A novel senolytic drug for pulmonary fibrosis: BTSA1 targets apoptosis of senescent myofibroblasts by activating BAX.
Shen M, Fu J, Zhang Y, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Zhou Y, Luo Z
Aging cell 2024 Sep;23(9):e14229
Aging cell 2024 Sep;23(9):e14229
METTL14-mediated methylation of SLC25A3 mitigates mitochondrial damage in osteoblasts, leading to the improvement of osteoporosis.
Wang P, Zhou W, Chen F, Zhang X, Zhang Q, Chen Y, Zhang N
Experimental gerontology 2024 Sep;194:112496
Experimental gerontology 2024 Sep;194:112496
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Xu X, Wang Y, Song Q, Zheng H, Lv J, Fu Z, Mao X, Li Y, Wu H, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Metabolic Control During Macrophage Polarization by a Citrate-Functionalized Scaffold for Maintaining Bone Homeostasis.
Wu X, Xia Y, Dai H, Hong C, Zhao Y, Wei W, Zheng D
Advanced healthcare materials 2024 Sep;13(22):e2400770
Advanced healthcare materials 2024 Sep;13(22):e2400770
A New Rat Model of Sacral Cord Injury Producing a Neurogenic Bladder and Its Functional and Mechanistic Studies.
Bai K, Hou Y, Zhang Z, Yuan F, Huang X, Liu P, Zou X, Sun J
Biomolecules 2024 Sep 9;14(9)
Biomolecules 2024 Sep 9;14(9)
Construction of multilayered small intestine-like tissue by reproducing interstitial flow.
Deguchi S, Kosugi K, Takeishi N, Watanabe Y, Morimoto S, Negoro R, Yokoi F, Futatsusako H, Nakajima-Koyama M, Iwasaki M, Yamamoto T, Kawaguchi Y, Torisawa YS, Takayama K
Cell stem cell 2024 Sep 5;31(9):1315-1326.e8
Cell stem cell 2024 Sep 5;31(9):1315-1326.e8
IKKα-STAT3-S727 axis: a novel mechanism in DOX-induced cardiomyopathy.
Chen G, Yao Y, Liu Y, Zhang R, Wen C, Zhou Q, Xu Y, Wang W, Jiang H, Tao Z, Chen W, Qiu Z, Chen X
Cellular and molecular life sciences : CMLS 2024 Sep 17;81(1):406
Cellular and molecular life sciences : CMLS 2024 Sep 17;81(1):406
TRIM16 mitigates impaired osteogenic differentiation and antioxidant response in D-galactose-induced senescent osteoblasts.
Li K, Huang K, Lu Q, Geng W, Jiang D, Guo A
European journal of pharmacology 2024 Sep 15;979:176849
European journal of pharmacology 2024 Sep 15;979:176849
Deficiency of geranylgeranyl biphosphate synthase in kidney tubules causes cystic kidney disease.
Shao X, Wang K, Wu J, Ma X, Zhao Y, Xu T, Dai C, Zhang F, Wang Y, Ren X, Lu K, Yin Z, Guo B, Cao C, Xu X, Xue B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 15;38(17):e23875
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Sep 15;38(17):e23875
Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice.
Zhang N, Zhang B, Chen X, Zhang Y, Wang Y, Lu S, Zhang H, Chen Y, Jiang H, Zhou H
International journal of biological macromolecules 2024 Sep 13;280(Pt 1):135550
International journal of biological macromolecules 2024 Sep 13;280(Pt 1):135550
Mechanosensitive Piezo1 channels promote neurogenic bladder fibrosis via regulating TGF-β1/smad and Hippo/YAP1 pathways.
Feng S, Yu Z, Yang Y, Xiong Q, Yan X, Bi Y
Experimental cell research 2024 Sep 1;442(1):114218
Experimental cell research 2024 Sep 1;442(1):114218
Chemotactic recruitment of genetically engineered cell membrane-camouflaged metal-organic framework nanoparticles for ischemic osteonecrosis treatment.
Jiang H, Xia W, Xia T, Jiang L, Yu J, Zhu X, Lin C, Lou C, Wang W, Chai Y, Wan R, Wang J, Xue X, Pan X
Acta biomaterialia 2024 Sep 1;185:410-428
Acta biomaterialia 2024 Sep 1;185:410-428
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Sun X, Wang N, Jiang H, Liu Q, Xiao C, Xu J, Wu Y, Mei J, Wu S, Lin Z
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.
Peng Z, Wang H, Zheng J, Chen H, Wang J, Weber HC, Yuan L, Qin X, Xiang Y, Liu C, Ji M, Liu H, Qu X
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13916
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13916
Calcipotriol abrogates TGF-β1/pSmad3-mediated collagen 1 synthesis in pancreatic stellate cells by downregulating RUNX1.
Zheng M, Li H, Sun L, Cui S, Zhang W, Gao Y, Gao R
Toxicology and applied pharmacology 2024 Oct;491:117078
Toxicology and applied pharmacology 2024 Oct;491:117078
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
Kong L, Liang Y, Hou J, Zhang W, Jiang S
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
Site-specific bioorthogonal regulation of bone morphogenetic protein 2 expression for effective bone regeneration.
Sun Y, Zhang X, Hong W, Qin Y, Man Y, He M, Liu JW, Chen J
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:577-589
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:577-589
Flexible and high-strength bioactive glass fiber membrane for bone regeneration with the aid of alkoxysilane sol spinnability.
Mao J, Sun J, Wang L, Liu X, Bi J
Materials today. Bio 2024 Oct;28:101224
Materials today. Bio 2024 Oct;28:101224
A photothermal responsive system accelerating nitric oxide release to enhance bone repair by promoting osteogenesis and angiogenesis.
Cheng Y, Huo Y, Yu Y, Duan P, Dong X, Yu Z, Cheng Q, Dai H, Pan Z
Materials today. Bio 2024 Oct;28:101180
Materials today. Bio 2024 Oct;28:101180
Melatonin-loaded bioactive microspheres accelerate aged bone regeneration by formation of tunneling nanotubes to enhance mitochondrial transfer.
Xiong H, Qiu H, Wang C, Qiu Y, Tan S, Chen K, Zhao F, Song J
Materials today. Bio 2024 Oct;28:101175
Materials today. Bio 2024 Oct;28:101175
RELA-mediated upregulation of LINC03047 promotes ferroptosis in silica-induced pulmonary fibrosis via SLC39A14.
Zhang B, Wang E, Zhou S, Han R, Wu W, Sun G, Cao C, Wang R
Free radical biology & medicine 2024 Oct;223:250-262
Free radical biology & medicine 2024 Oct;223:250-262
Liraglutide Promotes Diabetic Wound Healing via Myo1c/Dock5.
Zhang Q, Zhang C, Kang C, Zhu J, He Q, Li H, Tong Q, Wang M, Zhang L, Xiong X, Wang Y, Qu H, Zheng H, Zheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2405987
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2405987
The Effect of Metformin on Radiation-Induced Lung Fibrosis in Mice.
Chen YZ, Zhao L, Wei W, Gu J, Liu ZH, Shan WY, Dong J, Li C, Qin LQ, Xu JY
Dose-response : a publication of International Hormesis Society 2024 Oct-Dec;22(4):15593258241308051
Dose-response : a publication of International Hormesis Society 2024 Oct-Dec;22(4):15593258241308051
Decrease of Prolylcarboxypeptidase Dose of Aqueous Humor is Involved in the Pathogenesis of Primary Open-Angle Glaucoma via Finetuning of the Local Ocular Renin-Angiotensin System.
Ren J, Xiao Y, Wang D, Cui H, Zhao R, Guo Z, Wang Y, Zhu S, Tang B, Wang J, Wang G, Wang H, Hu X, Thorne RF, Duan S, Li H
Dose-response : a publication of International Hormesis Society 2024 Oct-Dec;22(4):15593258241298062
Dose-response : a publication of International Hormesis Society 2024 Oct-Dec;22(4):15593258241298062
S100A2 activation promotes interstitial fibrosis in kidneys by FoxO1-mediated epithelial-mesenchymal transition.
Yang X, Zheng F, Yan P, Liu X, Chen X, Du X, Zhang Y, Wang P, Chen C, Lu H, Bai Y
Cell biology and toxicology 2024 Oct 9;40(1):86
Cell biology and toxicology 2024 Oct 9;40(1):86
LMK235 ameliorates inflammation and fibrosis after myocardial infarction by inhibiting LSD1-related pathway.
Lv F, Xie L, Li L, Lin J
Scientific reports 2024 Oct 8;14(1):23450
Scientific reports 2024 Oct 8;14(1):23450
Albendazole ameliorates aerobic glycolysis in myofibroblasts to reverse pulmonary fibrosis.
Zeng C, Yue H, Wang C, Ju X, Wang T, Fu X, Zhou Q, Zhang H, He L, Yu J, Wang Y
Journal of translational medicine 2024 Oct 7;22(1):910
Journal of translational medicine 2024 Oct 7;22(1):910
Non-pharmacological interventions of intermittent fasting and pulsed radiofrequency energy (PRFE) combination therapy promote diabetic wound healing.
Huang Y, Qin P, Zhou P, Long B, Zhang S, Gao R, Zhu B, Li Y, Li Q
Nutrition & diabetes 2024 Oct 7;14(1):83
Nutrition & diabetes 2024 Oct 7;14(1):83
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition.
Zhuang Z, Liu A, Zhang J, Han S, Tang L, Yu T, Shi Y, Li H, Yang H, Bai P, Tang Y
Journal of translational medicine 2024 Oct 31;22(1):983
Journal of translational medicine 2024 Oct 31;22(1):983
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
Liu M, Song L, Lai Y, Gao F, Man J
Scientific reports 2024 Oct 30;14(1):26044
Scientific reports 2024 Oct 30;14(1):26044
Modification of transvaginal polypropylene mesh with co-axis electrospun nanofibrous membrane to alleviate complications following surgical implantation.
Guo T, Hu X, Du Z, Wang X, Lang J, Liu J, Xu H, Sun Z
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Journal of nanobiotechnology 2024 Oct 3;22(1):598
Construction and performance evaluation of fully biomimetic hyaline cartilage matrix scaffolds for joint defect regeneration.
Sun H, Wu Z, Liu L, Hu X, Zhao Y, Wang C, Yang J, Gu Z, Wang DA, Yao H
Biomedical materials (Bristol, England) 2024 Oct 28;19(6)
Biomedical materials (Bristol, England) 2024 Oct 28;19(6)
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation.
Wang G, Zhao R, Guo Z, Cui H, Wang D, Ren J, Zhu S, Zhang K, Tang B, Zhang J, Li P, Duan S, Li H
Human cell 2024 Oct 22;38(1):4
Human cell 2024 Oct 22;38(1):4
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation.
Liu C, Zhang Q, Zhou H, Jin L, Liu C, Yang M, Zhao X, Ding W, Xie W, Kong H
Journal of translational medicine 2024 Oct 21;22(1):954
Journal of translational medicine 2024 Oct 21;22(1):954
CCT6A alleviates pulmonary fibrosis by inhibiting HIF-1α-mediated lactate production.
Yan P, Yang K, Xu M, Zhu M, Duan Y, Li W, Liu L, Liang C, Li Z, Pan X, Wang L, Yu G
Journal of molecular cell biology 2024 Oct 21;16(5)
Journal of molecular cell biology 2024 Oct 21;16(5)
Nuclear receptor 4A1 ameliorates UUO-induced renal fibrosis by inhibiting the PI3K/AKT pathway.
Wang H, Wei Z, Xu C, Fang F, Wang Z, Zhong Y, Wang X
Scientific reports 2024 Oct 21;14(1):24787
Scientific reports 2024 Oct 21;14(1):24787
ADAM8 promotes alcoholic liver fibrosis through the MAPK signaling pathway.
Yang M, Li S, Luo R, Zhao Y, Sun Y, Li H, Cui Q, Wu J, Mao L
The journal of physiological sciences : JPS 2024 Oct 16;74(1):52
The journal of physiological sciences : JPS 2024 Oct 16;74(1):52
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels.
Liu DD, Liu XL, Zheng TF, Li X, Zhao YC, Pan JC, Yuan C, Wang QQ, Zhang M
European journal of pharmacology 2024 Oct 15;981:176875
European journal of pharmacology 2024 Oct 15;981:176875
NLRP3 inflammasome inhibition decreases Schistosomiasis japonica-induced granulomatous inflammation and fibrosis in BALB/c mice.
Lu Y, Liu J, Tang W, Zhang H
Infection and immunity 2024 Oct 15;92(10):e0005524
Infection and immunity 2024 Oct 15;92(10):e0005524
NIR-II light based combinatorial management of hypertrophic scar by inducing autophagy in fibroblasts.
Dong Y, Wang H, Zhang Y, Wu Y, Lu L, Yu H, Zhou L, Zhao P, Ouyang S, Song Z, Hu Z, Lv D, Rong Y, Zhao Z, Tao J, Tang B, Luo S
Journal of nanobiotechnology 2024 Oct 15;22(1):625
Journal of nanobiotechnology 2024 Oct 15;22(1):625
Asiaticoside improves diabetic nephropathy by reducing inflammation, oxidative stress, and fibrosis: An in vitro and in vivo study.
Zhuang LG, Zhang R, Jin GX, Pei XY, Wang Q, Ge XX
World journal of diabetes 2024 Oct 15;15(10):2111-2122
World journal of diabetes 2024 Oct 15;15(10):2111-2122
A proteomics-based study of the mechanism of oxymatrine to ameliorate hepatic fibrosis in mice.
Wu J, Jin X, Li W, Liu E
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2024 Oct 15;1247:124280
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2024 Oct 15;1247:124280
Leptin promotes tendon stem/progenitor cell senescence through the AKT-mTOR signaling pathway.
Lei C, Li Y, Chen J, Nie D, Song X, Lei C, Zhou Y, Wang W, Sun J
Experimental cell research 2024 Oct 1;442(2):114274
Experimental cell research 2024 Oct 1;442(2):114274
CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis.
Chen C, Feng C, Luo Q, Zeng Y, Yuan W, Cui Y, Tang Z, Zhang H, Li T, Peng J, Peng L, Xie X, Guo Y, Peng F, Jiang X, Bai P, Qi Z, Dai H
Life sciences 2024 Oct 1;354:122945
Life sciences 2024 Oct 1;354:122945
The LncRNA6524/miR-92a-2-5p/Dvl1/Wnt/β-catenin axis promotes renal fibrosis in the UUO mouse model.
Xie Y, Zhang G, Pan J, Qiu S, Zhang D
Archives of biochemistry and biophysics 2024 Nov;761:110175
Archives of biochemistry and biophysics 2024 Nov;761:110175
Injectable citrate-based polyurethane-urea as a tug-of-war-inspired bioactive self-expansive and planar-fixing screw augmented bone-tendon healing.
Tao M, Fang Z, Zhu Y, Ju Y, Hou Z, Fu M, Lu Z, Cai D, Yang J, Guo J
Bioactive materials 2024 Nov;41:108-126
Bioactive materials 2024 Nov;41:108-126
Targeted Therapy of Osteoarthritis via Intra-Articular Delivery of Lipid-Nanoparticle-Encapsulated Recombinant Human FGF18 mRNA.
Sun M, Ma B, Pan Z, Zhao Y, Tian L, Fan Y, Kong W, Wang J, Xu B, Ao Y, Guo Q, Wang X, Peng X, Li X, Cheng J, Miao L, Wang K, Hu X
Advanced healthcare materials 2024 Nov;13(29):e2400804
Advanced healthcare materials 2024 Nov;13(29):e2400804
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
Li HY, Xu XY, Lv SH, Chen W, Wang Y, Fu Y, Yang JP
Cellular signalling 2024 Nov;123:111373
Cellular signalling 2024 Nov;123:111373
Angiotensin II depends on hippo/YAP signaling to reprogram angiogenesis and promote liver fibrosis.
Zhou Y, Liang P, Bi T, Tang B, Zhu X, Liu X, Wang H, Shen H, Sun Q, Yang S, Ren W
Cellular signalling 2024 Nov;123:111355
Cellular signalling 2024 Nov;123:111355
Mitophagy deficiency activates stimulator of interferon genes activation and aggravates pathogenetic cardiac remodeling.
Zhou G, Wang X, Guo M, Qu C, Gao L, Yu J, Li Y, Luo S, Shi Q, Guo Y
Genes & diseases 2024 Nov;11(6):101074
Genes & diseases 2024 Nov;11(6):101074
Fusion protein of FGF21 and elastin-like peptide improves wound healing in diabetic mice via inflammation modulation, collagen synthesis, and vascular network formation.
Xiong F, Jiang X, Wu Y, Xiong J, Chen Y, Wang B, Ye X, Liang X
European journal of pharmacology 2024 Nov 5;982:176953
European journal of pharmacology 2024 Nov 5;982:176953
Targeting GPR39 in structure-based drug discovery reduces Ang II-induced hypertension.
Hua D, Huang W, Xie Q, Xu W, Tang L, Liu M, Wu X, Zhang Q, Cao X, Li P, Sheng Y
Communications biology 2024 Nov 5;7(1):1441
Communications biology 2024 Nov 5;7(1):1441
Quercetin Alleviates Scleral Remodeling Through Inhibiting the PERK-EIF2α Axis in Experiment Myopia.
Zhang M, Zhang R, Hao J, Zhao X, Ma Z, Peng Y, Bao B, Xin J, Yin X, Bi H, Guo D
Investigative ophthalmology & visual science 2024 Nov 4;65(13):11
Investigative ophthalmology & visual science 2024 Nov 4;65(13):11
Dexamethasone: a cheap and convenient way to alleviate subsequent stenosis after thermal injury on ureter.
Xia W, Huang F, Song Q, He Y, Li B
Translational andrology and urology 2024 Nov 30;13(11):2498-2509
Translational andrology and urology 2024 Nov 30;13(11):2498-2509
DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis.
Wang J, Xia Z, Qing B, Chen Y, Gu L, Chen H, Ge Z, Yuan Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):228
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):228
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis.
Zhang M, Zhang Y, He J, Wang X, Wang Y, Li L, Tao L, Zhang M, Shen X
Chinese medicine 2024 Nov 22;19(1):164
Chinese medicine 2024 Nov 22;19(1):164
Transcriptomics of tissue exosomes to investigate miR-195-5p's amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study.
Chen JM, Huang QY, Chen WH, Wu JX, Zheng LT, You HJ, Shi YC, Lin S, Shi QR
Journal of translational medicine 2024 Nov 21;22(1):1050
Journal of translational medicine 2024 Nov 21;22(1):1050
Exploring the role of iNOS in HFpEF-Related myocardial fibrosis: Involvement of PTEN-PI3K/AKT signaling pathway.
You H, Gou Q, Dong M, Chang F, Xiu J
Biochemical and biophysical research communications 2024 Nov 19;734:150589
Biochemical and biophysical research communications 2024 Nov 19;734:150589
CD248 interacts with ECM to promote hypertrophic scar formation and development.
Zhang L, Shang Y, Han C, Li M, Zhang J, Li Y, Shen K, Jia Y, Han D, Wen W, Yang Y, Hu D
Gene 2024 Nov 15;927:148730
Gene 2024 Nov 15;927:148730
Deacetylation of HnRNP U mediated by sirtuin1 ameliorates aged rat with liver fibrosis via inhibiting p53-related senescence and NLRP3-related inflammation.
Liu J, Ma X, Guo W, Lu B, Yue Y, Yang X, Wang R, Wu C, Zhang B, Li X, Luo X
International immunopharmacology 2024 Nov 15;141:113026
International immunopharmacology 2024 Nov 15;141:113026
Mechanics-activated fibroblasts promote pulmonary group 2 innate lymphoid cell plasticity propelling silicosis progression.
He Y, Yang F, Yang L, Yuan H, You Y, Chen Y, Wu X, Min H, Chen J, Li C
Nature communications 2024 Nov 12;15(1):9770
Nature communications 2024 Nov 12;15(1):9770
Overexpression of STX11 alleviates pulmonary fibrosis by inhibiting fibroblast activation via the PI3K/AKT/mTOR pathway.
Huang G, Yang X, Yu Q, Luo Q, Ju C, Zhang B, Chen Y, Liang Z, Xia S, Wang X, Xiang D, Zhong N, Tang XX
Signal transduction and targeted therapy 2024 Nov 11;9(1):306
Signal transduction and targeted therapy 2024 Nov 11;9(1):306
Gaudichaudione H ameliorates liver fibrosis and inflammation by targeting NRF2 signaling pathway.
Shi M, Guo Y, Xu J, Yan L, Li X, Liu R, Feng Y, Zhang Y, Zhao Y, Zhang C, Du K, Li M, Zhang Y, Zhang J, Li Z, Ren D, Liu P
Free radical biology & medicine 2024 Nov 1;224:770-784
Free radical biology & medicine 2024 Nov 1;224:770-784
Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways.
Zhao YN, Liu ZD, Yan T, Xu TX, Jin TY, Jiang YS, Zuo W, Lee KY, Huang LJ, Wang Y
Acta pharmacologica Sinica 2024 May;45(5):988-1001
Acta pharmacologica Sinica 2024 May;45(5):988-1001
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Fu TL, Li GR, Li DH, He RY, Liu BH, Xiong R, Xu CZ, Lu ZL, Song CK, Qiu HL, Wang WJ, Zou SS, Yi K, Li N, Geng Q
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Regulatory T cell-derived exosome mediated macrophages polarization for osteogenic differentiation in fracture repair.
Wu T, Wang L, Jian C, Gao C, Liu Y, Fu Z, Shi C
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:266-282
Journal of controlled release : official journal of the Controlled Release Society 2024 May;369:266-282
Factors Affecting the Evaluation of Collagen Deposition and Fibrosis In Vitro.
Fathi P, Sundaresan V, Alfonso AL, Rama Varma A, Sadtler K
Tissue engineering. Part A 2024 May;30(9-10):367-380
Tissue engineering. Part A 2024 May;30(9-10):367-380
Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis.
Song Q, Li H, Yan H, Yu Z, Li Z, Yuan J, Jiang N, Ni Z, Gu L, Fang W
Journal of cellular and molecular medicine 2024 May;28(10):e18381
Journal of cellular and molecular medicine 2024 May;28(10):e18381
Multifunctional tannic acid-based nanocomposite methacrylated silk fibroin hydrogel with the ability to scavenge reactive oxygen species and reduce inflammation for bone regeneration.
Wang R, He X, Su S, Bai J, Liu H, Zhou F
International journal of biological macromolecules 2024 May;266(Pt 2):131357
International journal of biological macromolecules 2024 May;266(Pt 2):131357
TGF-β1 inhibitor P144 protects against benign restenosis after esophageal stenting through TGF-β1/Smads signaling pathway inhibition.
Wu JZ, Zhou C, Liu S, Zhang JX, Yang W, Shi HB, Zhou WZ
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024 May;25(2):214-222
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024 May;25(2):214-222
Effect of polydimethylsiloxane surface morphology on osteogenic differentiation of mesenchymal stem cells through SIRT1 signalling pathway.
Hu Z, Yang F, Xiang P, Luo Z, Liang T, Xu H
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 2024 May;238(5):537-549
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 2024 May;238(5):537-549
METTL14 affects UVB-induced human dermal fibroblasts photoaging via miR-100-3p biogenesis in an m(6)A-dependent manner.
Chen L, Hu Y, Zhang M, Liu L, Ma J, Xu Z, Zhang J, Gu H, Chen K
Aging cell 2024 May;23(5):e14123
Aging cell 2024 May;23(5):e14123
Kefir peptides mitigate bleomycin-induced pulmonary fibrosis in mice through modulating oxidative stress, inflammation and gut microbiota.
Lan YW, Chen YC, Yen CC, Chen HL, Tung MC, Fan HC, Chen CM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116431
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116431
Cornus officinalis with high pressure wine steaming enhanced anti-hepatic fibrosis: Possible through SIRT3-AMPK axis.
Han X, Ning Y, Dou X, Wang Y, Shan Q, Shi K, Wang Z, Ding C, Hao M, Wang K, Peng M, Kuang H, Yang Q, Sang X, Cao G
Journal of pharmaceutical analysis 2024 May;14(5):100927
Journal of pharmaceutical analysis 2024 May;14(5):100927
Harnessing Mechanical Stress with Viscoelastic Biomaterials for Periodontal Ligament Regeneration.
Zhang JJ, Li X, Tian Y, Zou JK, Gan D, Deng DK, Jiao C, Yin Y, Tian BM, Wu RX, Chen FM, He XT
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(18):e2309562
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
Wang Y, Liu Y, Zhang Y, Zhang Z, Xu L, Wang J, Yang Y, Hu B, Yao Y, Wei M, Wang J, Tang B, Zhang K, Liu S, Yang G
European journal of medicinal chemistry 2024 May 5;271:116395
European journal of medicinal chemistry 2024 May 5;271:116395
Describing the Cellular Impact of IQOS™ Smoke Extract and Vibration on Human Vocal Fold Fibroblasts.
Grossmann T, Kirsch A, Gerstenberger C, Steffan B, Gugatschka M
Journal of voice : official journal of the Voice Foundation 2024 May 4;
Journal of voice : official journal of the Voice Foundation 2024 May 4;
DDX58 variant triggers IFN-β-induced autophagy in trabecular meshwork and influences intraocular pressure.
Huang X, Zhou X, Zhang F, Wang X, Duan X, Liu K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23651
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23651
Chaperone-mediated autophagy protects the bone formation from excessive inflammation through PI3K/AKT/GSK3β/β-catenin pathway.
Hang K, Wang Y, Bai J, Wang Z, Wu W, Zhu W, Liu S, Pan Z, Chen J, Chen W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23646
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23646
Inhibition of OGG1 ameliorates pulmonary fibrosis via preventing M2 macrophage polarization and activating PINK1-mediated mitophagy.
Wu W, Jia H, Chen S, Ma X, Zhou S, Qiu L, Wu X, Li P, Chu H, Zhang G
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Molecular medicine (Cambridge, Mass.) 2024 May 31;30(1):72
Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability.
Wang C, Wang X, Zhang Y, Mi Y, Han Y, Zhi Y, Zhao R, Cui N, Ma Q, Zhang H, Xue D, Qiao R, Han J, Yu Y, Li J, Shaiea M, Liu D, Gu G, Wang C
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
Acta biochimica et biophysica Sinica 2024 May 30;56(12):1802-1812
Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.
Wang J, Liu S, Sun L, Kong Z, Chai J, Wen J, Tian X, Chen N, Xu C
Scientific reports 2024 May 3;14(1):10206
Scientific reports 2024 May 3;14(1):10206
miR-19a-3p enhances TGF-β1-induced cardiac fibroblast activation via targeting BAMBI.
Shi P, Tan A, Ma Y, Que L, Li C, Shao Y, Sun H, Li Y, Li J
Journal of biomedical research 2024 May 29;39(2):171-183
Journal of biomedical research 2024 May 29;39(2):171-183
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Extracellular Vesicles Induce Fetal Wound Healing Features Revealed by Single-Cell RNA Sequencing.
Liu Y, Zhang M, Wang C, Chen H, Su D, Yang C, Tao Y, Lv X, Zhou Z, Li J, Liao Y, You J, Wang Z, Cheng F, Yang R
ACS nano 2024 May 28;18(21):13696-13713
ACS nano 2024 May 28;18(21):13696-13713
CRYAB suppresses ferroptosis and promotes osteogenic differentiation of human bone marrow stem cells via binding and stabilizing FTH1.
Tian B, Li X, Li W, Shi Z, He X, Wang S, Zhu X, Shi N, Li Y, Wan P, Zhu C
Aging 2024 May 22;16(10):8965-8979
Aging 2024 May 22;16(10):8965-8979
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
Bi G, Zhang X, Li W, Lu X, He X, Li Y, Bai R, Zhang H
Cell reports methods 2024 May 20;4(5):100778
Cell reports methods 2024 May 20;4(5):100778
MicroRNA-142-3p alleviated high salt-induced cardiac fibrosis via downregulating optineurin-mediated mitophagy.
Li Y, Zhao K, Hu Y, Yang F, Li P, Liu Y
iScience 2024 May 17;27(5):109764
iScience 2024 May 17;27(5):109764
2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis.
Peng F, Liao M, Jin W, Liu W, Li Z, Fan Z, Zou L, Chen S, Zhu L, Zhao Q, Zhan G, Ouyang L, Peng C, Han B, Zhang J, Fu L
Signal transduction and targeted therapy 2024 May 15;9(1):133
Signal transduction and targeted therapy 2024 May 15;9(1):133
Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects.
Wang FR, Peng ML, Zhu QF, Yu LL, Zhang LJ, Xu SY, Wang Q, Li J, He X, Liao SG, Ao JL, Xu GB
Journal of ethnopharmacology 2024 May 10;325:117830
Journal of ethnopharmacology 2024 May 10;325:117830
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
Xiang W, Yin G, Liu H, Wei J, Yu X, Xie Y, Zhang L, XueTang, Jiang W, Lu N
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Song B, Zhu Y, Zhao Y, Wang K, Peng Y, Chen L, Yu Z, Song B
International wound journal 2024 Mar;21(3):e14481
International wound journal 2024 Mar;21(3):e14481
OTUD1 promotes isoprenaline- and myocardial infarction-induced heart failure by targeting PDE5A in cardiomyocytes.
Wang Q, Liang S, Qian J, Xu J, Zheng Q, Wang M, Guo X, Min J, Wu G, Zhuang Z, Luo W, Liang G
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167018
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):167018
Characterization of Chitosan-Gallic Acid Graft Copolymer for Periodontal Dressing Hydrogel Application.
Feng M, Zeng X, Lin Q, Wang Y, Wei H, Yang S, Wang G, Chen X, Guo M, Yang X, Hu J, Zhang Y, Yang X, Du Y, Zhao Y
Advanced healthcare materials 2024 Mar;13(7):e2302877
Advanced healthcare materials 2024 Mar;13(7):e2302877
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Cheng P, Wang X, Liu Q, Yang T, Dai E, Sha W, Qu H, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Flexible Organic Photovoltaic-Powered Hydrogel Bioelectronic Dressing With Biomimetic Electrical Stimulation for Healing Infected Diabetic Wounds.
Hu YW, Wang YH, Yang F, Liu DX, Lu GH, Li ST, Wei ZX, Shen X, Jiang ZD, Zhao YF, Pang Q, Song BY, Shi ZW, Shafique S, Zhou K, Chen XL, Su WM, Jian JW, Tang KQ, Liu TL, Zhu YB
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2307746
Peptide-Based Hydrogel Scaffold Facilitates Articular Cartilage Damage Repair.
Chen C, Wu D, Wang Z, Liu L, He J, Li J, Chu B, Wang S, Yu B, Liu W
ACS applied materials & interfaces 2024 Mar 6;16(9):11336-11348
ACS applied materials & interfaces 2024 Mar 6;16(9):11336-11348
Astaxanthin attenuates cigarette smoke-induced small airway remodeling via the AKT1 signaling pathway.
Ding H, Yan L, Wang Y, Lu Y, Deng M, Wang Y, Wang Q, Zhou X
Respiratory research 2024 Mar 30;25(1):148
Respiratory research 2024 Mar 30;25(1):148
Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon.
Araiza-Olivera D, Prudnikova TY, Uribe-Alvarez C, Cai KQ, Franco-Barraza J, Dones JM, Raines RT, Chernoff J
bioRxiv : the preprint server for biology 2024 Mar 28;
bioRxiv : the preprint server for biology 2024 Mar 28;
Human periodontal ligament stem cell sheets activated by graphene oxide quantum dots repair periodontal bone defects by promoting mitochondrial dynamics dependent osteogenic differentiation.
An N, Yan X, Qiu Q, Zhang Z, Zhang X, Zheng B, Zhao Z, Guo J, Liu Y
Journal of nanobiotechnology 2024 Mar 27;22(1):133
Journal of nanobiotechnology 2024 Mar 27;22(1):133
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB
European journal of pharmacology 2024 Mar 15;967:176353
European journal of pharmacology 2024 Mar 15;967:176353
Polystyrene microplastic-induced extracellular vesicles cause kidney-related effects in the crosstalk between tubular cells and fibroblasts.
Wang YL, Huang CC, Zheng CM, Liu WC, Lee YH, Chiu HW
Ecotoxicology and environmental safety 2024 Mar 15;273:116098
Ecotoxicology and environmental safety 2024 Mar 15;273:116098
Tianhuang formula ameliorates liver fibrosis by inhibiting CCL2-CCR2 axis and MAPK/NF-κB signaling pathway.
Lan T, Chen B, Hu X, Cao J, Chen S, Ding X, Li S, Fu Y, Liu H, Luo D, Rong X, Guo J
Journal of ethnopharmacology 2024 Mar 1;321:117516
Journal of ethnopharmacology 2024 Mar 1;321:117516
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
Fibroblast-Specific Depletion of Human Antigen R Alleviates Myocardial Fibrosis Induced by Cardiac Stress.
Patil M, Singh S, Dubey PK, Tousif S, Umbarkar P, Zhang Q, Lal H, Sewell-Loftin MK, Umeshappa CS, Ghebre YT, Pogwizd S, Zhang J, Krishnamurthy P
JACC. Basic to translational science 2024 Jun;9(6):754-770
JACC. Basic to translational science 2024 Jun;9(6):754-770
In vitro modeling of recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-aminolevulinic acid photodynamic therapy efficacy.
Jiang H, He K, Tan J, Zhu D, Yang N, Wang Y, Zhang J, Li X, Ren Y, Lu Y
Photodiagnosis and photodynamic therapy 2024 Jun;47:104093
Photodiagnosis and photodynamic therapy 2024 Jun;47:104093
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
Wang X, Li X, Ma X, Zhang L, Han T, Zhang D
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
Calcitriol ameliorates the progression of hepatic fibrosis through autophagy-related gene 16-like 1-mediated autophagy.
Guo E, Yuan H, Li R, Yang J, Liu S, Liu A, Jiang X
The American journal of the medical sciences 2024 Jun;367(6):382-396
The American journal of the medical sciences 2024 Jun;367(6):382-396
The total xanthones extracted from Gentianella acuta alleviates HFpEF by activating the IRE1α/Xbp1s pathway.
Zhao L, Qin Y, Liu Y, An L, Liu W, Zhang C, Song Q, Dai C, Zhang J, Li A
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Journal of cellular and molecular medicine 2024 Jun;28(11):e18466
Injectable, stable, and biodegradable hydrogel with platelet-rich plasma induced by l-serine and sodium alginate for effective treatment of intrauterine adhesions.
Xie X, Ao X, Xu R, Lv H, Tan S, Wu J, Zhao L, Wang Y
International journal of biological macromolecules 2024 Jun;270(Pt 1):132363
International journal of biological macromolecules 2024 Jun;270(Pt 1):132363
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a.
Lou S, Zhu W, Yu T, Zhang Q, Wang M, Jin L, Xiong Y, Xu J, Wang Q, Chen G, Liang G, Hu X, Luo W
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167140
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167140
Protective role of hydrogen sulfide against diabetic cardiomyopathy by inhibiting pyroptosis and myocardial fibrosis.
Liu M, Zeng C, Zhang Y, Xin Y, Deng S, Hu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jun;175:116613
Synergistic effects of photodynamic therapy and chemotherapy: Activating the intrinsic/extrinsic apoptotic pathway of anoikis for triple-negative breast cancer treatment.
Zhang T, Wang X, Wang D, Lei M, Hu Y, Chen Z, Li Y, Luo Y, Zhang L, Zhu Y
Biomaterials advances 2024 Jun;160:213859
Biomaterials advances 2024 Jun;160:213859
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
Jin H, Liu Y, Lei Y, Li G, Huang L, Zhang Z
Toxicology research 2024 Jun;13(3):tfae067
Toxicology research 2024 Jun;13(3):tfae067
Gasdermin D silencing alleviates airway inflammation and remodeling in an ovalbumin-induced asthmatic mouse model.
Wu J, Wang P, Xie X, Yang X, Tang S, Zhao J, Liu T, Wang J, Zhang J, Xia T, Feng X
Cell death & disease 2024 Jun 7;15(6):400
Cell death & disease 2024 Jun 7;15(6):400
Involvement of necroptotic cell death in macrophages in progression of bleomycin and LPS-induced acute exacerbation of idiopathic pulmonary fibrosis.
Koike A, Hayashi K, Fujimori K
European journal of pharmacology 2024 Jun 5;972:176572
European journal of pharmacology 2024 Jun 5;972:176572
Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1(+) Th17 cells and fibroblasts.
Xu Y, Zheng C, Jiang P, Ji S, Ullah S, Zhao Y, Su D, Xu G, Zhang M, Zou X
International immunopharmacology 2024 Jun 30;135:112298
International immunopharmacology 2024 Jun 30;135:112298
Platelet membrane biomimetic nanoparticle-targeted delivery of TGF-β1 siRNA attenuates renal inflammation and fibrosis.
Fei S, Ma Y, Zhou B, Chen X, Zhang Y, Yue K, Li Q, Gui Y, Xiang T, Liu J, Yang B, Wang L, Huang X
International journal of pharmaceutics 2024 Jun 25;659:124261
International journal of pharmaceutics 2024 Jun 25;659:124261
The Development of a 3D PET Fibrous Scaffold Modified with an Umbilical Cord dECM for Liver Tissue Engineering.
Li Y, Zhang Y, Zhong K, Liao S, Zhang G
Polymers 2024 Jun 25;16(13)
Polymers 2024 Jun 25;16(13)
Cold exposure-induced plasma exosomes impair bone mass by inhibiting autophagy.
Lei LM, Li FX, Lin X, Xu F, Shan SK, Guo B, Zheng MH, Tang KX, Wang Y, Xu QS, Ouyang WL, Duan JY, Wu YY, Cao YC, Zhou ZA, He SY, Wu YL, Chen X, Lin ZJ, Pan Y, Yuan LQ, Li ZH
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Journal of nanobiotechnology 2024 Jun 23;22(1):361
Sodium arsenite induces hepatic stellate cells activation by m(6)A modification of TGF-β1 during liver fibrosis.
Qiu T, Hou K, Zhang J, Wang N, Yao X, Yang G, Jiang L, Dong J, Miao M, Bai J, Sun X
Ecotoxicology and environmental safety 2024 Jun 15;278:116435
Ecotoxicology and environmental safety 2024 Jun 15;278:116435
Trigonelline hydrochloride attenuates silica-induced pulmonary fibrosis by orchestrating fibroblast to myofibroblast differentiation.
Zhang F, Yue H, Dong R, He J, Zhou L, Dou X, Wang L, Zheng P, Mao Z, Zhu X, Wang Y, Liu H, Zhang H
Respiratory research 2024 Jun 15;25(1):242
Respiratory research 2024 Jun 15;25(1):242
CircFgfr2 promotes osteogenic differentiation of rat dental follicle cells by targeting the miR-133a-3p/DLX3 signaling pathway.
Xu C, Xu Z, Li G, Li J, Ye L, Ning Y, Du Y
Heliyon 2024 Jun 15;10(11):e32498
Heliyon 2024 Jun 15;10(11):e32498
Alantolactone attenuates high-fat diet-induced inflammation and oxidative stress in non-alcoholic fatty liver disease.
Wang J, Jiang Y, Jin L, Qian C, Zuo W, Lin J, Xie L, Jin B, Zhao Y, Huang L, Wang Y
Nutrition & diabetes 2024 Jun 10;14(1):41
Nutrition & diabetes 2024 Jun 10;14(1):41
C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis.
Hu W, Wang Y, Yang H, Zhang L, Liu B, Ji Y, Song X, Lv C, Zhang S
Archives of pharmacal research 2024 Jul;47(7):659-674
Archives of pharmacal research 2024 Jul;47(7):659-674
Carnosol prevents cardiac remodeling and ventricular arrhythmias in pressure overload-induced heart failure mice.
Fang Z, Lu M, Huang R, Wang G, Yushanjiang F, Jiang X, Li J
Phytotherapy research : PTR 2024 Jul;38(7):3763-3781
Phytotherapy research : PTR 2024 Jul;38(7):3763-3781
Alginate-containing 3D-printed hydrogel scaffolds incorporated with strontium promotes vascularization and bone regeneration.
Miao A, Li Q, Tang G, Lu Q
International journal of biological macromolecules 2024 Jul;273(Pt 1):133038
International journal of biological macromolecules 2024 Jul;273(Pt 1):133038
Intracellular and extracellular Cyclophilin a promote cardiac fibrosis through TGF-β signaling in response to angiotensin Ⅱ.
Cao M, Zhao Q, Xia H, Lyu S, Luo J, Fu K, Chen R, Yuan W
Biochemical pharmacology 2024 Jul;225:116271
Biochemical pharmacology 2024 Jul;225:116271
Picroside II promotes HSC apoptosis and inhibits the cholestatic liver fibrosis in Mdr2(-/-) mice by polarizing M1 macrophages and balancing immune responses.
Jia K, Ma Z, Zhang Y, Xie K, Li J, Wu J, Qu J, Li F, Li X
Chinese journal of natural medicines 2024 Jul;22(7):582-598
Chinese journal of natural medicines 2024 Jul;22(7):582-598
LGR5 Modulates Differentiated Phenotypes of Chondrocytes Through PI3K/AKT Signaling Pathway.
Wu X, Fu Y, Ma J, Li C, He A, Zhang T
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Tissue engineering and regenerative medicine 2024 Jul;21(5):791-807
Long Non-coding RNA ZFAS1 Regulates Fibrosis and Scortosis in the Cell Model of Diabetic Nephropathy Through miR-525-5p/SGK1 Axis.
Zhuang L, Jin G, Wang Q, Ge X, Pei X
Applied biochemistry and biotechnology 2024 Jul;196(7):3731-3746
Applied biochemistry and biotechnology 2024 Jul;196(7):3731-3746
Hierarchically Biomimetic Scaffolds with Anisotropic Micropores and Nanotopological Patterns to Promote Bone Regeneration via Geometric Modulation.
Wei X, Chen J, Shen HY, Jiang K, Ren H, Liu Y, Luo E, Zhang J, Xu JZ, Li ZM
Advanced healthcare materials 2024 Jul;13(17):e2304178
Advanced healthcare materials 2024 Jul;13(17):e2304178
Lapagyl mitigates UV-induced inflammation and immunosuppression via Foxp3+ Tregs and CCL pathway: A single-cell transcriptomics study.
Xie Y, Yang A, Li N, Zheng H, Zhong Y, Jin Y, Li J, Ye R, Du L, Hu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155679
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155679
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
Hu D, Lai J, Chen Q, Bai L
Stem cell research & therapy 2024 Jul 6;15(1):199
Stem cell research & therapy 2024 Jul 6;15(1):199
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition.
Zhang Z, Hu J
Journal of translational medicine 2024 Jul 3;22(1):617
Journal of translational medicine 2024 Jul 3;22(1):617
Aggregation-Induced Emission CN-Based Nanoparticles to Alleviate Hypoxic Liver Fibrosis via Triggering HSC Ferroptosis and Enhancing Photodynamic Therapy.
Liu MX, Cai YT, Wang RJ, Zhu PF, Liu YC, Sun H, Ling Y, Zhu WZ, Chen J, Zhang XL
ACS applied materials & interfaces 2024 Jul 3;16(26):33021-33037
ACS applied materials & interfaces 2024 Jul 3;16(26):33021-33037
Salvianolic acid B protects against UVB-induced skin aging via activation of NRF2.
Sun JM, Liu YX, Liu YD, Ho CK, Tsai YT, Wen DS, Huang L, Zheng DN, Gao Y, Zhang YF, Yu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155676
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155676
Flexible Sono-Piezo Patch for Functional Sweat Gland Repair through Endogenous Microenvironmental Remodeling.
Pi W, Chen H, Liu Y, Xiang J, Zhang H, Yang X, Zhang M, Cao J, Chang T, Zheng Y, Liu S, Zhang H, Han Q, Liu K, Fu X, Shao Y, Sun X
ACS nano 2024 Jul 22;
ACS nano 2024 Jul 22;
Mesenchymal stem cells ameliorate inflammation and pyroptosis in diabetic cardiomyopathy via the miRNA-223-3p/NLRP3 pathway.
Yang Q, Chen Q, Li S, Luo J
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
Diabetology & metabolic syndrome 2024 Jul 2;16(1):146
Comparative Analysis of Decellularization Methods for the Production of Decellularized Umbilical Cord Matrix.
Li Y, Zhang Y, Zhang G
Current issues in molecular biology 2024 Jul 19;46(7):7686-7701
Current issues in molecular biology 2024 Jul 19;46(7):7686-7701
CircSMAD3 represses SMAD3 phosphorylation and ameliorates cardiac remodeling by recruiting YBX1.
Mei S, Ma X, Zhou L, Wuyun Q, Wang J, Xiao Q, Wang M, Zhang K, Chen C, Yan J, Ding H
iScience 2024 Jul 19;27(7):110200
iScience 2024 Jul 19;27(7):110200
Procyanidin C1 inhibits bleomycin-induced pulmonary fibrosis in mice by selective clearance of senescent myofibroblasts.
Shao M, Qiu Y, Shen M, Liu W, Feng D, Luo Z, Zhou Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23749
Isorhamnetin inhibits hypertrophic scar formation through TGF-β1/Smad and TGF-β1/CREB3L1 signaling pathways.
Wu J, Song Y, Wang J, Wang T, Yang L, Shi Y, Song B, Yu Z
Heliyon 2024 Jul 15;10(13):e33802
Heliyon 2024 Jul 15;10(13):e33802
Targeting of G protein-coupled receptor 39 alleviates angiotensin II-induced renal damage by reducing ribonucleotide reductase M2.
Hua D, Huang W, Xu W, Zhang Y, Xie Q, Li P, Sheng Y
Experimental cell research 2024 Jul 1;440(1):114102
Experimental cell research 2024 Jul 1;440(1):114102
A new mechanism in negative pressure wound therapy: interleukin-17 alters chromatin accessibility profiling.
Xiao S, Wang W, Zhao C, Ren P, Dong L, Zhang H, Ma F, Li X, Bian Y
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
American journal of physiology. Cell physiology 2024 Jul 1;327(1):C193-C204
ROS-responsive core-shell nano-inhibitor impedes pyruvate metabolism for reinforced photodynamic therapy and interrupted pre-metastatic niche formation.
Lv M, Zhao B, Zhang J, Miao G, Wei S, Tang Y, Liu X, Qian H, Huang D, Chen W, Zhong Y
Acta biomaterialia 2024 Jul 1;182:288-300
Acta biomaterialia 2024 Jul 1;182:288-300
Cysteine and glycine-rich protein 2 retards platelet-derived growth factor-BB-evoked phenotypic transition of airway smooth muscle cells by decreasing YAP/TAZ activity.
Wang H, Zhang Y, Zhong B, Geng Y, Hao J, Jin Q, Hou W
Cell biochemistry and function 2024 Jan;42(1):e3896
Cell biochemistry and function 2024 Jan;42(1):e3896
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
Zhang Q, Li Y, Wang S, Gu D, Zhang C, Xu S, Fang X, Li C, Wu H, Xiong W
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Su X, Li S, Zhang Y, Tie X, Feng R, Guo X, Qiao X, Wang L
The American journal of pathology 2024 Jan;194(1):101-120
The American journal of pathology 2024 Jan;194(1):101-120
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Inhibition of TGFβ1 activation prevents radiation-induced lung fibrosis.
Yi M, Yuan Y, Ma L, Li L, Qin W, Wu B, Zheng B, Liao X, Hu G, Liu B
Clinical and translational medicine 2024 Jan;14(1):e1546
Clinical and translational medicine 2024 Jan;14(1):e1546
Intermittent mild cold stimulation alleviates cold stress-induced pulmonary fibrosis by inhibiting the TGF-β1/Smad signaling pathway in broilers.
Wei H, Zhang Y, Li T, Zhang S, Yin J, Liu Y, Xing L, Bao J, Li J
Poultry science 2024 Jan;103(1):103246
Poultry science 2024 Jan;103(1):103246
Regulation of the immune microenvironment by pioglitazone-loaded polylactic glycolic acid nanosphere composite scaffolds to promote vascularization and bone regeneration.
Fan S, Tan Y, Yuan X, Liu C, Wu X, Dai T, Ni S, Wang J, Weng Y, Zhao H
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Journal of tissue engineering 2024 Jan-Dec;15:20417314241231452
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Zhao WM, Li XL, Zhu Y, Shi R, Wang ZJ, Xiao JP, Wang DG
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
Nanoscaled Titanium Oxide Layer Provokes Quick Osseointegration on 3D-Printed Dental Implants: A Domino Effect Induced by Hydrophilic Surface.
Shu T, Wang X, Li M, Ma S, Cao J, Sun G, Lai T, Liu S, Li A, Qu Z, Pei D
ACS nano 2024 Jan 9;18(1):783-797
ACS nano 2024 Jan 9;18(1):783-797
Hsa_circ_0081065 exacerbates IH-induced EndMT via regulating miR-665/HIF-1α signal axis and HIF-1α nuclear translocation.
Jiang S, Xing X, Hong M, Zhang X, Xu F, Zhang GH
Scientific reports 2024 Jan 9;14(1):904
Scientific reports 2024 Jan 9;14(1):904
Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.
Shuangshuang H, Mengmeng S, Lan Z, Fang Z, Yu L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Li G, Ren Y, Li E, Deng K, Qu C, Zhang J, Zhang L, Wang X, Lian J, Zhou H, Wang Z, Shen T, Li X, Jiang Z
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.
Feng H, Yang L, Yang H, Cheng D, Li M, Song E, Xu T
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
Molecular therapy : the journal of the American Society of Gene Therapy 2024 Jan 3;32(1):218-226
Morroniside-mediated mitigation of stem cell and endothelial cell dysfunction for the therapy of glucocorticoid-induced osteonecrosis of the femoral head.
Jiang H, Wang W, Mao Y, Jiang L, Yu J, Zhu X, Fu H, Lin Z, Shen H, Pan X, Xue X
International immunopharmacology 2024 Jan 25;127:111421
International immunopharmacology 2024 Jan 25;127:111421
Rejuvenating Hyaline Cartilaginous Phenotype of Dedifferentiated Chondrocytes in Collagen II Scaffolds: A Mechanism Study Using Chondrocyte Membrane Nanoaggregates as Antagonists.
Zhou H, Mu Y, Ma C, Zhang Z, Tao C, Wang DA
ACS nano 2024 Jan 23;18(3):2077-2090
ACS nano 2024 Jan 23;18(3):2077-2090
S100A8/A9 promotes endometrial fibrosis via regulating RAGE/JAK2/STAT3 signaling pathway.
Xin X, Liu H, Zhang S, Li P, Zhao X, Zhang X, Li S, Wu S, Zhao F, Tan J
Communications biology 2024 Jan 22;7(1):116
Communications biology 2024 Jan 22;7(1):116
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
Wang Y, Wen C, Jing R, Yang Y, Qin Y, Qi T, Hu C, Bai X, Wu C, Pei C
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Hua Q, Ren L
Chinese medicine 2024 Jan 18;19(1):12
Chinese medicine 2024 Jan 18;19(1):12
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
JOSD2 mediates isoprenaline-induced heart failure by deubiquitinating CaMKIIδ in cardiomyocytes.
Xu J, Liang S, Wang Q, Zheng Q, Wang M, Qian J, Yu T, Lou S, Luo W, Zhou H, Liang G
Cellular and molecular life sciences : CMLS 2024 Jan 10;81(1):18
Cellular and molecular life sciences : CMLS 2024 Jan 10;81(1):18
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Zhu JH, Wang L, Ma ZX, Duan JA, Tao JH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Oxidative modification of collagen by malondialdehyde in porcine skin.
Paculová V, Prasad A, Sedlářová M, Pospíšil P
Archives of biochemistry and biophysics 2024 Feb;752:109850
Archives of biochemistry and biophysics 2024 Feb;752:109850
Microplastics cause hepatotoxicity in diabetic mice by disrupting glucolipid metabolism via PP2A/AMPK/HNF4A and promoting fibrosis via the Wnt/β-catenin pathway.
Li X, Feng L, Kuang Q, Wang X, Yang J, Niu X, Gao L, Huang L, Luo P, Li L
Environmental toxicology 2024 Feb;39(2):1018-1030
Environmental toxicology 2024 Feb;39(2):1018-1030
Nerve growth factor promote osteogenic differentiation of dental pulp stem cells through MEK/ERK signalling pathways.
Cheng C, Tang S, Cui S, Yang T, Li L, Zhai M, Wei F, Ding G
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
Journal of cellular and molecular medicine 2024 Feb;28(4):e18143
An Injectable Composite Hydrogel of Verteporfin-Bonded Carboxymethyl Chitosan and Oxidized Sodium Alginate Facilitates Scarless Full-Thickness Skin Regeneration.
Yang JT, Wu D, Li J, Zhao C, Zhu L, Xu C, Xu N
Macromolecular bioscience 2024 Feb;24(2):e2300165
Macromolecular bioscience 2024 Feb;24(2):e2300165
Tanshinone IIA ameliorates energy metabolism dysfunction of pulmonary fibrosis using (13)C metabolic flux analysis.
Shan B, Zhou H, Guo C, Liu X, Wu M, Zhai R, Chen J
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
Journal of pharmaceutical analysis 2024 Feb;14(2):244-258
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
Ren Y, Li G, Li E, Deng K, Lian J, Gao Q, Wang H, Wang X, Wang Z, Shen T, Jiang Z, Li X, Qiu G
European journal of pharmacology 2024 Feb 5;964:176272
European journal of pharmacology 2024 Feb 5;964:176272
In Vitro and In Vivo Bone-Forming Effect of a Low-Molecular-Weight Collagen Peptide.
Hwang JM, Lee MH, Kwon Y, Chung HC, Kim DU, Lee JH
Journal of microbiology and biotechnology 2024 Feb 28;34(2):415-424
Journal of microbiology and biotechnology 2024 Feb 28;34(2):415-424
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Wang Y, Li X, Guan X, Song Z, Liu H, Guan Z, Wang J, Zhu L, Zhang D, Zhao L, Xie P, Wei X, Shang N, Liu Y, Jin Z, Ji Z, Dai G
International journal of molecular sciences 2024 Feb 27;25(5)
International journal of molecular sciences 2024 Feb 27;25(5)
Endothelial Robo4 suppresses endothelial-to-mesenchymal transition induced by irradiation and improves hematopoietic reconstitution.
Adzraku SY, Cao C, Zhou Q, Yuan K, Hao X, Li Y, Yuan S, Huang Y, Xu K, Qiao J, Ju W, Zeng L
Cell death & disease 2024 Feb 21;15(2):159
Cell death & disease 2024 Feb 21;15(2):159
miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway.
Wei J, Chen Y, Feng T, Wei Y, Yang C, Zhang C, Li W, Liu G
Functional & integrative genomics 2024 Feb 20;24(2):37
Functional & integrative genomics 2024 Feb 20;24(2):37
[Ubiquitin-specific protease 42 regulates osteogenic differentiation of human adipose-derived stem cells].
Pan Y, Gu H, Xiao H, Zhao L, Tang Y, Ge W
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2024 Feb 18;56(1):9-16
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2024 Feb 18;56(1):9-16
Pharmacological inhibition of ICOS attenuates the protective effect of exercise on cardiac fibrosis induced by isoproterenol.
Peng Y, Qin D, Wang Y, Gao W, Xu X
European journal of pharmacology 2024 Feb 15;965:176327
European journal of pharmacology 2024 Feb 15;965:176327
M(3) subtype of muscarinic acetylcholine receptor inhibits cardiac fibrosis via targeting microRNA-29b/beta-site app cleaving enzyme 1 axis.
Li W, Yu J, Yang Y, Wang J, Liu Y, Wang J, Hu J, Yuan Y, Du Z
Cardiovascular diagnosis and therapy 2024 Feb 15;14(1):143-157
Cardiovascular diagnosis and therapy 2024 Feb 15;14(1):143-157
CRP inhibits the osteoblastic differentiation of OPCs via the up-regulation of primary cilia and repression of the Hedgehog signaling pathway.
Xu J, Wu X, Zhu H, Zhu Y, Du K, Deng X, Wang C
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
Medical oncology (Northwood, London, England) 2024 Feb 12;41(3):72
PUD@HA/PEEK Scaffold Induces Subchondral Bone Regeneration to Repair Osteochondral Defect in Rabbits.
Li M, Teng M, Mao G, Sun Y, Liu S, Li R, Wang X, Qiu Y
ACS biomaterials science & engineering 2024 Feb 12;10(2):1006-1017
ACS biomaterials science & engineering 2024 Feb 12;10(2):1006-1017
Buyang Huanwu Decoction suppresses cardiac inflammation and fibrosis in mice after myocardial infarction through inhibition of the TLR4 signalling pathway.
Zhang G, Han X, Xu T, Liu M, Chen G, Xie L, Xu H, Hua Y, Pang M, Hu C, Wu Y, Liu B, Zhou Y
Journal of ethnopharmacology 2024 Feb 10;320:117388
Journal of ethnopharmacology 2024 Feb 10;320:117388
Halofuginone ameliorates the susceptibility to atrial fibrillation by activating the PI3K/Akt signaling pathway.
Xu F, Zhao X, Zhang J, Shen C
Journal of molecular histology 2024 Dec;55(6):1295-1306
Journal of molecular histology 2024 Dec;55(6):1295-1306
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Shen C, Jiang Y, Lin J, Guo Q, Fang D
Journal of molecular histology 2024 Dec;55(6):1163-1175
Journal of molecular histology 2024 Dec;55(6):1163-1175
[(18)F]AlF-CBP imaging of type I collagen for non-invasive monitoring of pulmonary fibrosis in preclinical models.
Liu Y, Tang P, Peng S, Zhong J, Xu Z, Zhong J, Su J, Zhong Y, Hu K
European journal of nuclear medicine and molecular imaging 2024 Dec;52(1):22-35
European journal of nuclear medicine and molecular imaging 2024 Dec;52(1):22-35
Mesenchymal stem cells may alleviate angiotensin II-induced myocardial fibrosis and hypertrophy by upregulating SFRS3 expression.
Gu L, Wan X, Liu Y, Gong Z, Huang R, Shi Y, Liu H
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 2024 Dec;43(12):645-656
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Li L, Jin RJ, Ji L
Environmental toxicology 2024 Dec;39(12):5382-5390
Environmental toxicology 2024 Dec;39(12):5382-5390
α-Mangostin Attenuates Blood Pressure and Reverses Vascular Remodeling by Balancing ACE/AT1R and ACE2/Ang-(1-7)/MasR Axes in Ang II-Infused Hypertensive Mice.
Xue QQ, Liu CH, Zhang DY, Li MX, Li Y
Phytotherapy research : PTR 2024 Dec;38(12):5918-5929
Phytotherapy research : PTR 2024 Dec;38(12):5918-5929
Macrophage polarization and macrophage-related factor expression in hypertrophy of the ligamentum flavum.
Jiang C, Wang W, Chen YL, Chen JH, Zhang ZW, Li J, Yang ZC, Li XC
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2024 Dec;33(12):4476-4487
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2024 Dec;33(12):4476-4487
Exploring the anti‑oxidative mechanisms of Rhodiola rosea in ameliorating myocardial fibrosis through network pharmacology and in vitro experiments.
Zhang L, Yin H, Xie Y, Zhang Y, Dong F, Wu K, Yang L, Lv H
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Dihydrolipoamide S-acetyltransferase activation alleviates diabetic kidney disease via AMPK-autophagy axis and mitochondrial protection.
Zhou P, Wang N, Lu S, Xiong J, Zhang Y, Jiang Q, Qian Q, Zhou Q, Liu J, Chen S
Translational research : the journal of laboratory and clinical medicine 2024 Dec;274:81-100
Translational research : the journal of laboratory and clinical medicine 2024 Dec;274:81-100
Heat shock protein 27 downregulation attenuates isoprenaline-induced myocardial fibrosis and diastolic dysfunction by modulating the endothelial-mesenchymal transition.
Zou Y, Shi H, Li Y, Li T, Liu N, Liu B
Biochemical pharmacology 2024 Dec;230(Pt 3):116612
Biochemical pharmacology 2024 Dec;230(Pt 3):116612
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
Zhang Y, Wang X, Huang J, Zhang X, Bu L, Zhang Y, Liang F, Wu S, Zhang M, Zhang L, Zhang L
Aging cell 2024 Dec;23(12):e14333
Aging cell 2024 Dec;23(12):e14333
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
Wu D, Zhang H, Li F, Liu S, Wang Y, Zhang Z, Wang J, Wu Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
An anti-RAGE chimeric antibody alleviates CCl(4)-induced liver fibrosis via RAGE/NF-kB pathway in mice.
Liu J, Li H, Chen H, Xiao X, Jin Z, Paerhati P, Bao W, Cui C, Zhu J, Yuan Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117737
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Dec;181:117737
Diagnostic significance of LncRNA MIAT in periodontitis and the molecular mechanisms influencing periodontal ligament fibroblasts via the miR-204-5p/DKK1 axis.
Ren Y, Zheng J, Cao Y, Zhu Y, Ling Z, Zhang Z, Huang M
Archives of oral biology 2024 Dec;168:106066
Archives of oral biology 2024 Dec;168:106066
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
Wang X, Ren J, Fang F, Wang E, Li J, He W, Zhang Z, Shen Y, Liu X
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
The JNK-associated leucine zipper protein exerts a protective effect on renal parenchymal injury by limiting the inflammatory secretome in tubular cells.
Li C, Wang X, Tian M, Zhang M, Zhang X, Fu Q, Liu L, Zhang L, Wang H
Cellular signalling 2024 Dec;124:111428
Cellular signalling 2024 Dec;124:111428
Genetic Characteristics of the Rat Fibroblast Cell Line Rat-1.
Liehr T, Kankel S, Buhl EM, Schröder-Lange SK, Weiskirchen R
Cells 2024 Dec 29;14(1)
Cells 2024 Dec 29;14(1)
LCCP exposure leads to skin cell senescence damage by triggering oxidative stress mediated by mitochondrial Ca(2+) overload.
Zhang M, Zhang R, Kong Y, Li J, Wang G, Wu D, Wu M, Lan H
International immunopharmacology 2024 Dec 25;143(Pt 2):113471
International immunopharmacology 2024 Dec 25;143(Pt 2):113471
The bach1/G9a/Slc7a11 axis epigenetically promotes renal fibrosis by mediated ferroptosis.
Yao X, Yang S, Chen L, Lin F, Ruan Y, Rao T, Cheng F
International immunopharmacology 2024 Dec 25;143(Pt 1):113363
International immunopharmacology 2024 Dec 25;143(Pt 1):113363
Cell membrane-camouflaged nanoparticles activate fibroblast-myofibroblast transition to promote skin wound healing.
Jia Q, Ding Y, Su Z, Chen H, Ye J, Xie D, Wu Y, He H, Peng Y, Ni Y
Biofabrication 2024 Dec 23;17(1)
Biofabrication 2024 Dec 23;17(1)
Baicalin improves isoproterenol-induced cardiac remodeling by regulating the Nrf2-dependent signaling pathway.
Qian K, Song L, Guo JM, Fu D, Shi J, Ma Y, Ge ZJ, Li L, Zhang SQ
BMC cardiovascular disorders 2024 Dec 20;24(1):733
BMC cardiovascular disorders 2024 Dec 20;24(1):733
Myricetin Alleviates Silica-Mediated Lung Fibrosis via PPARγ-PGC-1α Loop and Suppressing Mitochondrial Senescence in Epithelial Cells.
Xie W, Deng L, Zhang X, Huang X, Ding J, Liu W, Tang SY
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Journal of agricultural and food chemistry 2024 Dec 18;72(50):27737-27749
Cerium Oxide Nanoparticles-Reinforced GelMA Hydrogel Loading Bone Marrow Stem Cells with Osteogenic and Inflammatory Regulatory Capacity for Bone Defect Repair.
Wang R, He X, Bai J, Su S, Zhou R, Gao S, Liu H, Zhou F
ACS applied materials & interfaces 2024 Dec 11;16(49):67373-67384
ACS applied materials & interfaces 2024 Dec 11;16(49):67373-67384
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes.
Wang D, Yu X, Gao K, Li F, Li X, Pu H, Zhang P, Guo S, Wang W
Redox biology 2024 Aug;74:103223
Redox biology 2024 Aug;74:103223
Vaspin facilitates the proliferation and osteogenic differentiation of periodontal ligament stem cells.
Jing Z, Feng X, Li X, Zhang X, Pan C
Journal of periodontal research 2024 Aug;59(4):812-820
Journal of periodontal research 2024 Aug;59(4):812-820
Serum deprivation protein response intervenes in the proliferation, motility, and extracellular matrix production in keloid fibroblasts by blocking the amplification of TGF-β1/SMAD signal cascade via ERK1/2.
Li P, Han M, Wang L, Gao C
Toxicology and applied pharmacology 2024 Aug;489:117012
Toxicology and applied pharmacology 2024 Aug;489:117012
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1.
Deng BL, Lin DX, Li ZP, Li K, Wei PY, Luo CC, Zhang MY, Zhou Q, Yang ZL, Chen Z
Current medical science 2024 Aug;44(4):718-725
Current medical science 2024 Aug;44(4):718-725
A Superparamagnetic Composite Hydrogel Scaffold as In Vivo Dynamic Monitorable Theranostic Platform for Osteoarthritis Regeneration.
Rong M, Liu D, Xu X, Li A, Bai Y, Yang G, Liu K, Zhang Z, Wang L, Wang K, Lu L, Jiang Y, Liu J, Zhang X
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(35):e2405641
Advanced materials (Deerfield Beach, Fla.) 2024 Aug;36(35):e2405641
Macromolecular Crowding Enhances Matrix Protein Deposition in Tissue-Engineered Vascular Grafts.
Liu Q, Liu J, Sun XH, Xu JY, Xiao C, Jiang HJ, Wu YD, Lin ZY
Tissue engineering. Part A 2024 Aug;30(15-16):473-484
Tissue engineering. Part A 2024 Aug;30(15-16):473-484
Aldehyde Dehydrogenase 2 Deficiency Aggravates Lung Fibrosis through Mitochondrial Dysfunction and Aging in Fibroblasts.
Wei Y, Gao S, Li C, Huang X, Xie B, Geng J, Dai H, Wang C
The American journal of pathology 2024 Aug;194(8):1458-1477
The American journal of pathology 2024 Aug;194(8):1458-1477
Bulk and single-cell transcriptome profiling identify potential cellular targets of the long noncoding RNA Gas5 in renal fibrosis.
Zhang X, Hu S, Xiang X, Li Z, Chen Z, Xia C, He Q, Jin J, Chen H
Biochimica et biophysica acta. Molecular basis of disease 2024 Aug;1870(6):167206
Biochimica et biophysica acta. Molecular basis of disease 2024 Aug;1870(6):167206
PGC-1α/LDHA signaling facilitates glycolysis initiation to regulate mechanically induced bone remodeling under inflammatory microenvironment.
Liu J, Wang J, Wang Z, Ren H, Zhang Z, Fu Y, Li L, Shen Z, Li T, Tang S, Wei F
Bone 2024 Aug;185:117132
Bone 2024 Aug;185:117132
Injectable, degradable, and mechanically adaptive hydrogel induced by L-serine and allyl-functionalized chitosan with platelet-rich plasma for treating intrauterine adhesions.
Lv H, Xu R, Xie X, Liang Q, Yuan W, Xia Y, Ao X, Tan S, Zhao L, Wu J, Wang Y
Acta biomaterialia 2024 Aug;184:144-155
Acta biomaterialia 2024 Aug;184:144-155
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Zhou S, Guo L, Cui X, Zhang X, Yang Y, Zhang M, Zhang P
Cellular signalling 2024 Aug;120:111217
Cellular signalling 2024 Aug;120:111217
GelMA loaded with platelet lysate promotes skin regeneration and angiogenesis in pressure ulcers by activating STAT3.
Jin T, Fu Z, Zhou L, Chen L, Wang J, Wang L, Yan S, Li T, Jin P
Scientific reports 2024 Aug 7;14(1):18345
Scientific reports 2024 Aug 7;14(1):18345
Gas6-Axl signal promotes indoor VOCs exposure-induced pulmonary fibrosis via pulmonary microvascular endothelial cells-fibroblasts cross-talk.
Liu Q, Niu Y, Pei Z, Yang Y, Xie Y, Wang M, Wang J, Wu M, Zheng J, Yang P, Hao H, Pang Y, Bao L, Dai Y, Niu Y, Zhang R
Journal of hazardous materials 2024 Aug 5;474:134786
Journal of hazardous materials 2024 Aug 5;474:134786
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion.
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F
Progress in orthodontics 2024 Aug 5;25(1):30
Progress in orthodontics 2024 Aug 5;25(1):30
Titanium nanoparticles released from orthopedic implants induce muscle fibrosis via activation of SNAI2.
Zhang G, Deng L, Jiang Z, Xiang G, Zeng Z, Zhang H, Wang Y
Journal of nanobiotechnology 2024 Aug 30;22(1):522
Journal of nanobiotechnology 2024 Aug 30;22(1):522
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Zheng JH, Zhu YH, Yang J, Ji PX, Zhao RK, Duan ZH, Yao HF, Jia QY, Yin YF, Hu LP, Li Q, Jiang SH, Huo YM, Liu W, Sun YW, Liu DJ
Cell reports 2024 Aug 27;43(8):114633
Cell reports 2024 Aug 27;43(8):114633
miR-450a-2-3p targets ERK(1/2) to ameliorate ISO-induced cardiac fibrosis in mice.
Liu L, Luo F
Genes & nutrition 2024 Aug 19;19(1):16
Genes & nutrition 2024 Aug 19;19(1):16
USP36 regulates the proliferation, survival, and differentiation of hFOB1.19 osteoblast.
Yan J, Gu X, Gao X, Shao Y, Ji M
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Journal of orthopaedic surgery and research 2024 Aug 17;19(1):483
Association of IL-9 Cytokines with Hepatic Injury in Echinococcus granulosus Infection.
Zhou T, Xu X, Zhu J, Aizezi M, Aierken A, Meng M, He R, Aimulajiang K, Wen H
Biomolecules 2024 Aug 14;14(8)
Biomolecules 2024 Aug 14;14(8)
METTL3 Promotes Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration by Regulating TLR2 m6A Methylation and Gut Microbiota.
Ni S, Huang X, Li X, Shi C, Fan M, Zhao L, Rong Z, Zhang H
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Aug 1;79(8)
The journals of gerontology. Series A, Biological sciences and medical sciences 2024 Aug 1;79(8)
A novel PDGFR inhibitor WQ-C-401 prevents pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.
Huang W, Zhou H, He Y, Wang A, Wang B, Chen Y, Liu C, Wang H, Xie W, Kong H
Experimental cell research 2024 Aug 1;441(1):114154
Experimental cell research 2024 Aug 1;441(1):114154
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
Targeting S100A9 Prevents β-Adrenergic Activation-Induced Cardiac Injury.
Liu J, Chen X, Zeng L, Zhang L, Wang F, Peng C, Huang X, Li S, Liu Y, Shou W, Li X, Cao D
Inflammation 2024 Apr;47(2):789-806
Inflammation 2024 Apr;47(2):789-806
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition.
Wu Q, Liu WJ, Ma XY, Chang JS, Zhao XY, Liu YH, Yu XY
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
Acta pharmacologica Sinica 2024 Apr;45(4):738-750
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
Tan X, Wang J, Liu X, Xie G, Ouyang F
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
Schwann cell derived pleiotrophin stimulates fibroblast for proliferation and excessive collagen deposition in plexiform neurofibroma.
Tian Z, Du Z, Bai G, Gong Q, You Y, Xu G, Liu J, Xiao M, Wang Y, He Y
Cancer gene therapy 2024 Apr;31(4):627-640
Cancer gene therapy 2024 Apr;31(4):627-640
SLC15A3 plays a crucial role in pulmonary fibrosis by regulating macrophage oxidative stress.
Luo J, Li P, Dong M, Zhang Y, Lu S, Chen M, Zhou H, Lin N, Jiang H, Wang Y
Cell death and differentiation 2024 Apr;31(4):417-430
Cell death and differentiation 2024 Apr;31(4):417-430
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Xu W, Mo W, Han D, Dai W, Xu X, Li J, Xu X
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Herb pair of Rhubarb-Astragalus mitigates renal interstitial fibrosis through downregulation of autophagy via p38-MAPK/TGF-β1 and p38-MAPK/smad2/3 pathways.
Li J, Qin X, Xu W, Zhang H, Huang S, Yang Y, Qin M, Mi Z, Zhong X
The international journal of biochemistry & cell biology 2024 Apr;169:106549
The international journal of biochemistry & cell biology 2024 Apr;169:106549
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Wei J, Wang DF, Cui CC, Tan JJ, Peng MY, Lu HX
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Immunity, inflammation and disease 2024 Apr;12(4):e1237
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway.
Zhang T, Cao RJ, Niu JL, Chen ZH, Mu SQ, Cao T, Pang JX, Dong LH
Cellular & molecular biology letters 2024 Apr 8;29(1):47
Cellular & molecular biology letters 2024 Apr 8;29(1):47
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
Zeng Q, Wen BB, Liu X, Luo YY, Hu ZG, Huang L, Zhang XH, Huang XT, Zhou TT, Sang XX, Luo YY, Xiong DY, Luo ZQ, Liu W, Tang SY
Chinese medicine 2024 Apr 8;19(1):60
Chinese medicine 2024 Apr 8;19(1):60
Histone methyltransferase Suv39h1 regulates hepatic stellate cell activation and is targetable in liver fibrosis.
Kong M, Zhou J, Kang A, Kuai Y, Xu H, Li M, Miao X, Guo Y, Fan Z, Xu Y, Li Z
Gut 2024 Apr 5;73(5):810-824
Gut 2024 Apr 5;73(5):810-824
GKT137831 in combination with adipose-derived stem cells alleviates high glucose-induced inflammaging and improves diabetic wound healing.
Dong Y, Zhang Y, Li F, Tang B, Lv D, Wang H, Luo S
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Journal of leukocyte biology 2024 Apr 29;115(5):882-892
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
Liang D, Liu L, Qi Y, Nan F, Huang J, Tang S, Tang J, Chen N
Journal of ethnopharmacology 2024 Apr 24;324:117745
Journal of ethnopharmacology 2024 Apr 24;324:117745
Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling.
Zhong D, Chen J, Qiao R, Song C, Hao C, Zou Y, Bai M, Su W, Yang B, Sun D, Jia Z, Sun Y
Cell reports 2024 Apr 23;43(4):114075
Cell reports 2024 Apr 23;43(4):114075
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization.
Zhang R, Jiang Q, Gao S, Zhang H, Xia Q, Liu B, Zhu J, Jiang H, Zhao R, Dong H, Li X, Zhang Y, Yang C, Gu X, Sun L, Zhou H
International immunopharmacology 2024 Apr 20;131:111774
International immunopharmacology 2024 Apr 20;131:111774
ED-71 ameliorates bone regeneration in type 2 diabetes by reducing ferroptosis in osteoblasts via the HIF1α pathway.
Wang M, Liu Y, Gui H, Ma G, Li B, Zhang Z, Yu G, Wu A, Xu X, Zhang D
European journal of pharmacology 2024 Apr 15;969:176303
European journal of pharmacology 2024 Apr 15;969:176303
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Li Y, Zuo C, Wu X, Ding Y, Wei Y, Chen S, Lu X, Xu J, Liu S, Zhou G, Cai L
Cell death & disease 2024 Apr 13;15(4):263
Cell death & disease 2024 Apr 13;15(4):263
LncRNA GAS5 restrains ISO-induced cardiac fibrosis by modulating mir-217 regulation of SIRT1.
Zhang YH, Sun TT, Liu ZH, Li X, Fan XF, Han LP
Scientific reports 2024 Apr 1;14(1):7652
Scientific reports 2024 Apr 1;14(1):7652
Photocurable 3D-printed PMBG/TCP biphasic scaffold mimicking vasculature for bone regeneration.
Zhang C, Ren Y, Kong W, Liu Y, Li H, Yang H, Cai B, Dai K, Wang C, Tang L, Niu H, Wang J
International journal of bioprinting 2023;9(5):767
International journal of bioprinting 2023;9(5):767
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Pan Y, Liu Y
Allergologia et immunopathologia 2023;51(4):71-77
Allergologia et immunopathologia 2023;51(4):71-77
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Mao X, Xie X, Ma J, Wei Y, Huang Z, Wang T, Zhu J, Wang Y, Zhao H, Hua J
Biological & pharmaceutical bulletin 2023;46(7):929-938
Biological & pharmaceutical bulletin 2023;46(7):929-938
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
Li X, Yao Y, Wei L
Iranian journal of basic medical sciences 2023;26(9):1047-1052
Iranian journal of basic medical sciences 2023;26(9):1047-1052
hUMSCs Restore Uterine Function by Inhibiting Endometrial Fibrosis via Regulation of the MMP-9/TIMP-1 Ratio in CDDP-Induced Injury Rats.
Tang Y, Si Y, Liu C, Li C, Qu L, Liu Y, Fu Q, Luo Q
Stem cells international 2023;2023:8014052
Stem cells international 2023;2023:8014052
IFN-α-2b Reduces Postoperative Arthrofibrosis in Rats by Inhibiting Fibroblast Proliferation and Migration through STAT1/p21 Signaling Pathway.
Liu Z, Fan Z, Wang R, Li X, Chen H, Wang J
Mediators of inflammation 2023;2023:1699946
Mediators of inflammation 2023;2023:1699946
Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail Signaling.
Wu Y, Bai Y, Feng Y, Zhang Q, Diao Z, Liu W
International journal of medical sciences 2023;20(5):669-681
International journal of medical sciences 2023;20(5):669-681
Hyaluronic acid hydrogels support to generate integrated bone formation through endochondral ossification in vivo using mesenchymal stem cells.
Yamazaki S, Hirayama R, Ikeda Y, Iseki S, Yoda T, Ikeda MA
PloS one 2023;18(2):e0281345
PloS one 2023;18(2):e0281345
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Wang X, Yan X, Huang F, Wu L
Open life sciences 2023;18(1):20220679
Open life sciences 2023;18(1):20220679
Combining Porous Se@SiO(2) Nanocomposites and dECM Enhances the Myogenic Differentiation of Adipose-Derived Stem Cells.
Zhang YC, Yang YX, Liu Y, Liu XJ, Dai JH, Gao RS, Hu YY, Fei WY
International journal of nanomedicine 2023;18:7661-7676
International journal of nanomedicine 2023;18:7661-7676
Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment.
Zhang Y, Han X, Wang K, Liu D, Ding X, Hu Z, Wang J
International journal of nanomedicine 2023;18:4329-4346
International journal of nanomedicine 2023;18:4329-4346
Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats.
Yao M, Lian D, Wu M, Zhou Y, Fang Y, Zhang S, Zhang W, Yang Y, Li R, Chen H, Chen Y, Shen A, Peng J
Drug design, development and therapy 2023;17:2749-2762
Drug design, development and therapy 2023;17:2749-2762
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Yu R, Yuan Y, Liu Z, Liu L, Xu Z, Zhao Y, Jia C, Zhang P, Li H, Liu Y, Wang Y, Li W, Nie L, Sun X, Li Y, Liu B, Liu H
Frontiers in immunology 2023;14:1171150
Frontiers in immunology 2023;14:1171150
Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease.
Zhu E, Liu Y, Zhong M, Liu Y, Jiang X, Shu X, Li N, Guan H, Xia Y, Li J, Lan HY, Zheng Z
Frontiers in immunology 2023;14:1142240
Frontiers in immunology 2023;14:1142240
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
Lu J, Gao J, Sun J, Wang H, Sun H, Huang Q, Zhang Y, Zhong S
Frontiers in pharmacology 2023;14:1106339
Frontiers in pharmacology 2023;14:1106339
Gastrodin attenuates renal injury and collagen deposition via suppression of the TGF-β1/Smad2/3 signaling pathway based on network pharmacology analysis.
Wen Y, Zhang X, Wei L, Wu M, Cheng Y, Zheng H, Shen A, Fu C, Ali F, Long L, Lu Y, Li J, Peng J
Frontiers in pharmacology 2023;14:1082281
Frontiers in pharmacology 2023;14:1082281
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer.
Li X, Luo X, Hu S
BioImpacts : BI 2023;13(2):89-96
BioImpacts : BI 2023;13(2):89-96
S100 calcium-binding protein A9 promotes skin regeneration through toll-like receptor 4 during tissue expansion.
Zhang Y, Song Y, Du J, Liu W, Dong C, Huang Z, Zhang Z, Yang L, Wang T, Xiong S, Dong L, Guo Y, Dang J, He Q, Yu Z, Ma X
Burns & trauma 2023;11:tkad030
Burns & trauma 2023;11:tkad030
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Zhu Y, Wang T, Bao MJ, Qu XH, Li ZM
Frontiers in bioengineering and biotechnology 2023;11:1168136
Frontiers in bioengineering and biotechnology 2023;11:1168136
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Association of FOXO3A with right ventricular myocardial fibrosis and its detection by speckle-tracking echocardiography in pulmonary hypertension.
Song R, Wang P, Yang L, Liu J, Chen Z, Ding Y
Echocardiography (Mount Kisco, N.Y.) 2023 Sep;40(9):958-968
Echocardiography (Mount Kisco, N.Y.) 2023 Sep;40(9):958-968
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524
The journal of gene medicine 2023 Sep;25(9):e3524
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Axitinib attenuates the progression of liver fibrosis by restoring mitochondrial function.
Li H, Zhang R, Hu Y, Li J, Yang Y, Wu D, Gu X, Zhang F, Zhou H, Yang C
International immunopharmacology 2023 Sep;122:110555
International immunopharmacology 2023 Sep;122:110555
Gentianella acuta-derived Gen-miR-1 suppresses myocardial fibrosis by targeting HAX1/HMG20A/Smads axis to attenuate inflammation in cardiac fibroblasts.
Zhang T, Zhang Y, Li S, Ge H, Song Q, Zhang Y, Yang G, Li A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154923
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Peng H, Xie M, Zhong X, Su Y, Qin X, Xu Q, Zhou S
European journal of pharmacology 2023 Sep 5;954:175849
European journal of pharmacology 2023 Sep 5;954:175849
Inhibition of ACSL4 ameliorates tubular ferroptotic cell death and protects against fibrotic kidney disease.
Dai Y, Chen Y, Mo D, Jin R, Huang Y, Zhang L, Zhang C, Gao H, Yan Q
Communications biology 2023 Sep 5;6(1):907
Communications biology 2023 Sep 5;6(1):907
Site-specific Atg13 methylation-mediated autophagy regulates epithelial inflammation in PM2.5-induced pulmonary fibrosis.
Ning J, Pei Z, Wang M, Hu H, Chen M, Liu Q, Wu M, Yang P, Geng Z, Zheng J, Du Z, Hu W, Wang Q, Pang Y, Bao L, Niu Y, Leng S, Zhang R
Journal of hazardous materials 2023 Sep 5;457:131791
Journal of hazardous materials 2023 Sep 5;457:131791
Impaired autophagy activity-induced abnormal differentiation of bone marrow stem cells is related to adolescent idiopathic scoliosis osteopenia.
Zhang H, Yang G, Li J, Xiao L, Guo C, Wang Y
Chinese medical journal 2023 Sep 5;136(17):2077-2085
Chinese medical journal 2023 Sep 5;136(17):2077-2085
Omentin-1 induces mechanically activated fibroblasts lipogenic differentiation through pkm2/yap/pparγ pathway to promote lung fibrosis resolution.
Zhang Y, Fu J, Li C, Chang Y, Li X, Cheng H, Qiu Y, Shao M, Han Y, Feng D, Yue S, Sun Z, Luo Z, Zhou Y
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):308
Multi-targeting liposomal codelivery of cisplatin and rapamycin inhibits pancreatic cancer growth and metastasis through stromal modulation.
Zhu W, Yu H, Jia M, Lin C, Yuan Z, Tan X, Yan P
International journal of pharmaceutics 2023 Sep 25;644:123316
International journal of pharmaceutics 2023 Sep 25;644:123316
Construction of a Collagen-like Protein Based on Elastin-like Polypeptide Fusion and Evaluation of Its Performance in Promoting Wound Healing.
Chen Y, Wu Y, Xiong F, Yu W, Wang T, Xiong J, Zhou L, Hu F, Ye X, Liang X
Molecules (Basel, Switzerland) 2023 Sep 23;28(19)
Molecules (Basel, Switzerland) 2023 Sep 23;28(19)
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts.
Zhang L, Liu HH, Yang F, Zhang ZY, Wu Y, Li F, Dang SP, Zhang ZY, Qian LL, Wang RX
BMC cardiovascular disorders 2023 Sep 21;23(1):474
BMC cardiovascular disorders 2023 Sep 21;23(1):474
Near-Infrared Light-Controlled MicroRNA-21-Loaded Upconversion Nanoparticles to Promote Bone Formation in the Midpalatal Suture.
Liu B, Wang B, Wang Z, Meng Y, Li Y, Li L, Wang J, Zhai M, Liu R, Wei F
ACS applied materials & interfaces 2023 Sep 20;15(37):43503-43514
ACS applied materials & interfaces 2023 Sep 20;15(37):43503-43514
Efficient intervention for pulmonary fibrosis via mitochondrial transfer promoted by mitochondrial biogenesis.
Huang T, Lin R, Su Y, Sun H, Zheng X, Zhang J, Lu X, Zhao B, Jiang X, Huang L, Li N, Shi J, Fan X, Xu D, Zhang T, Gao J
Nature communications 2023 Sep 18;14(1):5781
Nature communications 2023 Sep 18;14(1):5781
Qingda granule ameliorates vascular remodeling and phenotypic transformation of adventitial fibroblasts via suppressing the TGF-β1/Smad2/3 pathway.
Wu M, Zhang S, Zhang W, Zhou Y, Guo Z, Fang Y, Yang Y, Shen Z, Lian D, Shen A, Peng J
Journal of ethnopharmacology 2023 Sep 15;313:116535
Journal of ethnopharmacology 2023 Sep 15;313:116535
Human adipose ECM alleviates radiation-induced skin fibrosis via endothelial cell-mediated M2 macrophage polarization.
Chinnapaka S, Yang KS, Surucu Y, Bengur FB, Arellano JA, Tirmizi Z, Malekzadeh H, Epperly MW, Hou W, Greenberger JS, Rubin JP, Ejaz A
iScience 2023 Sep 15;26(9):107660
iScience 2023 Sep 15;26(9):107660
MYCT1 attenuates renal fibrosis and tubular injury in diabetic kidney disease.
Li X, Fan QL, Ma TK, Liu C, Shi H, Sun YY, Wang Y, Ding DX, Tang A, Qin Y, Yang Q, Ding H, Li HY, Fu WN
iScience 2023 Sep 15;26(9):107609
iScience 2023 Sep 15;26(9):107609
Overexpression of KLF4 Suppresses Pulmonary Fibrosis through the HIF-1α/Endoplasmic Reticulum Stress Signaling Pathway.
Wei S, Qi F, Wu Y, Liu X
International journal of molecular sciences 2023 Sep 12;24(18)
International journal of molecular sciences 2023 Sep 12;24(18)
Robust Osteoconductive β-Tricalcium Phosphate/L-poly(lactic acid) Membrane via Orientation-Strengthening Technology.
Liu S, Chen W, Xiao L, Zhao Z, Liu F, Lu S, Chen C, Luo W, Jiang L, Li Y
ACS biomaterials science & engineering 2023 Sep 11;9(9):5293-5303
ACS biomaterials science & engineering 2023 Sep 11;9(9):5293-5303
Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis.
Kong X, Zhao Y, Wang X, Yu Y, Meng Y, Yan G, Yu M, Jiang L, Song W, Wang B, Wang X
Chemico-biological interactions 2023 Sep 1;382:110640
Chemico-biological interactions 2023 Sep 1;382:110640
N-methylpiperazine-diepoxyovatodiolide ameliorates peritoneal fibrosis via suppressing TGF-β/Smad and JAK/STAT signaling pathway.
Mo M, Zeng Y, Zeng Y, Li S, He X, Chen X, Luo Q, Liu M, Luo C, Dou X, Peng F, Long H
Chemico-biological interactions 2023 Sep 1;382:110589
Chemico-biological interactions 2023 Sep 1;382:110589
UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathway.
Cui S, Zhang X, Li Y, Hu S, Wu B, Fang Z, Gao J, Li M, Wu H, Tao B, Xia H, Xu L
Cellular & molecular biology letters 2023 Sep 1;28(1):71
Cellular & molecular biology letters 2023 Sep 1;28(1):71
Increased Expression of Adipokines in Patients With Frozen Shoulder.
Qiao Y, Yao X, Zhao Y, Kang Y, Xu C, Zhao J, Zhao S
The American journal of sports medicine 2023 Oct;51(12):3261-3267
The American journal of sports medicine 2023 Oct;51(12):3261-3267
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
Zhu ZD, Zhang M, Wang Z, Jiang CR, Huang CJ, Cheng HJ, Guan QY, Su TT, Wang MM, Gao Y, Wu HF, Wei W, Han YS, Wang QT
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
CHI3L1 promotes myocardial fibrosis via regulating lncRNA TUG1/miR-495-3p/ETS1 axis.
Sun Y, Shan X, Guo J, Liu X, Ma D
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1436-1451
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1436-1451
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Zhang L, Li W, Liu X, Guo J, Wu X, Wang J
Experimental eye research 2023 Oct;235:109628
Experimental eye research 2023 Oct;235:109628
Myeloid-specific deletion of Capns1 attenuates myocardial infarction injury via restoring mitochondrial function and inhibiting inflammasome activation.
Xiao Z, Wei X, Li M, Yang K, Chen R, Su Y, Yu Z, Liang Y, Ge J
Journal of molecular and cellular cardiology 2023 Oct;183:54-66
Journal of molecular and cellular cardiology 2023 Oct;183:54-66
Inhibition of annexin A7 suppresses senescence-associated heterochromatin foci formation and senescence through the AMPK/mTOR pathway in human dermal fibroblasts.
Li N, Yan X, Cui X, Zhao C, Lin Z, Miao J
Journal of cellular biochemistry 2023 Oct;124(10):1603-1614
Journal of cellular biochemistry 2023 Oct;124(10):1603-1614
Farnesoid X receptor activation is required for the anti-inflammatory and anti-oxidative stress effects of Alisol B 23-acetate in carbon tetrachloride-induced liver fibrosis in mice.
Zhang L, Lin W, Cai Y, Huang Z, Zhao R, Yan T, Xu H, Liu Z
International immunopharmacology 2023 Oct;123:110768
International immunopharmacology 2023 Oct;123:110768
Photocurable 3D-Printed PMBG/TCP Scaffold Coordinated with PTH (1-34) Bidirectionally Regulates Bone Homeostasis to Accelerate Bone Regeneration.
Ren Y, Kong W, Liu Y, Yang X, Xu X, Qiang L, Mi X, Zhang C, Niu H, Wang C, Wang J
Advanced healthcare materials 2023 Oct;12(25):e2300292
Advanced healthcare materials 2023 Oct;12(25):e2300292
Downregulation of fibromodulin attenuates inflammatory signaling and atrial fibrosis in spontaneously hypertensive rats with atrial fibrillation via inhibiting TLR4/NLRP3 signaling pathway.
Liang Y, Zhou Y, Wang J, He Y
Immunity, inflammation and disease 2023 Oct;11(10):e1003
Immunity, inflammation and disease 2023 Oct;11(10):e1003
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling.
Shu G, Sun H, Zhang T, Zhu A, Lei X, Wang C, Song A, Deng X
European journal of pharmacology 2023 Oct 5;956:175964
European journal of pharmacology 2023 Oct 5;956:175964
Caveolin-1 scaffolding domain peptide prevents corpus cavernosum fibrosis and erectile dysfunction in bilateral cavernous nerve injury-induced rats.
Xi Y, Ge Y, Hu D, Xia T, Chen J, Zhang C, Cui Y, Xiao H
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
The journal of sexual medicine 2023 Oct 31;20(11):1274-1284
Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes.
Zhang L, Liu HH, Yang F, Zhang ZY, Zhang ZY, Zhao XX, Qian LL, Dang SP, Wang RX
Diabetology & metabolic syndrome 2023 Oct 28;15(1):217
Diabetology & metabolic syndrome 2023 Oct 28;15(1):217
Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis.
Xia W, Chen X, Zhu Z, Chen H, Li B, Wang K, Huang L, Liu Z, Chen Z
Scientific reports 2023 Oct 23;13(1):18076
Scientific reports 2023 Oct 23;13(1):18076
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
He X, Yang L, Wang M, Zhang P, Wang R, Ji D, Gao C, Xia Z
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
Substrate-dependent interaction of SPOP and RACK1 aggravates cardiac fibrosis following myocardial infarction.
Yang W, Zhuang Y, Wu H, Su S, Li Y, Wang C, Tian Z, Peng L, Zhang X, Liu J, Pei X, Yuan W, Hu X, Meng B, Li D, Zhang Y, Shan H, Pan Z, Lu Y
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Cell chemical biology 2023 Oct 19;30(10):1248-1260.e4
Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53.
Zhang C, Zheng Z, Xu K, Cheng G, Wu H, Liu J
International journal of molecular sciences 2023 Oct 17;24(20)
International journal of molecular sciences 2023 Oct 17;24(20)
Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients.
Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman HI, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R, Kidney Precision Medicine Project
The Journal of clinical investigation 2023 Oct 16;133(20)
The Journal of clinical investigation 2023 Oct 16;133(20)
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
Zheng M, Li H, Gao Y, Brigstock DR, Gao R
European journal of pharmacology 2023 Oct 15;957:176000
European journal of pharmacology 2023 Oct 15;957:176000
Inhibition of miR-543 alleviates cardiac fibroblast-to-myofibroblast transformation and collagen expression in insulin resistance via targeting PTEN.
Tan YM, Cao LY, Jiao YQ, Han L, Tang MX, Wang ZH, Zhang W, Zhong M, Zhang L
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Molecular and cellular endocrinology 2023 Oct 1;576:111996
Structural analysis and attenuates hyperuricemic nephropathy of dextran from the Imperata cylindrica Beauv. var. major (Nees) C. E. Hubb.
Yu W, Xiong Y, Liu M, Zeng D, Zhao H, Liu J, Lu W
Carbohydrate polymers 2023 Oct 1;317:121064
Carbohydrate polymers 2023 Oct 1;317:121064
Single-nucleus RNA sequencing reveals heterogenous microenvironments and specific drug response between cervical squamous cell carcinoma and adenocarcinoma.
Lin S, Sun Y, Cao C, Zhu Z, Xu Y, Liu B, Hu B, Peng T, Zhi W, Xu M, Ding W, Ren F, Ma D, Li G, Wu P
EBioMedicine 2023 Nov;97:104846
EBioMedicine 2023 Nov;97:104846
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Xu L, Jiang H, Xie J, Xu Q, Zhou J, Lu X, Wang M, Dong L, Zuo D
Heliyon 2023 Nov;9(11):e21882
Heliyon 2023 Nov;9(11):e21882
Local administration of liposomal-based Plekhf1 gene therapy attenuates pulmonary fibrosis by modulating macrophage polarization.
Yan L, Hou C, Liu J, Wang Y, Zeng C, Yu J, Zhou T, Zhou Q, Duan S, Xiong W
Science China. Life sciences 2023 Nov;66(11):2571-2586
Science China. Life sciences 2023 Nov;66(11):2571-2586
Macrophage RAGE deficiency prevents myocardial fibrosis by repressing autophagy-mediated macrophage alternative activation.
He J, Wei L, Tan S, Liang B, Liu J, Lu L, Wang T, Wang J, Huang Y, Chen Z, Li H, Zhang L, Zhou Z, Cao Y, Ye X, Yang Z, Xian S, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23259
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23259
Knockdown of Bach1 protects periodontal bone regeneration from inflammatory damage.
Yuan Z, Li J, Zou X, Liu C, Lu J, Ni C, Tang L, Wu X, Yan F
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Journal of cellular and molecular medicine 2023 Nov;27(22):3465-3477
Aryl hydrocarbon receptor regulates IL-22 receptor expression on thymic epithelial cell and accelerates thymus regeneration.
Shen J, Wang Y, Zheng F, Cao S, Lan Q, Xu K, Pan B
NPJ Regenerative medicine 2023 Nov 8;8(1):64
NPJ Regenerative medicine 2023 Nov 8;8(1):64
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
BSHXF-medicated serum combined with ADSCs regulates the TGF-β1/Smad pathway to repair oxidatively damaged NPCs and its component analysis.
Duan J, Li Z, Liu E, Long H, Chen L, Yang S
Journal of ethnopharmacology 2023 Nov 15;316:116692
Journal of ethnopharmacology 2023 Nov 15;316:116692
Injectable kaempferol-loaded fibrin glue regulates the metabolic balance and inhibits inflammation in intervertebral disc degeneration.
Gao W, Bao J, Zhang Y, He D, Zhang L, Zhang J, Pan H, Wang D
Scientific reports 2023 Nov 15;13(1):20001
Scientific reports 2023 Nov 15;13(1):20001
Hyaluronic acid-mediated collagen intrafibrillar mineralization and enhancement of dentin remineralization.
Wu H, Shao C, Shi J, Hu Z, Zhou Y, Chen Z, Tang R, Xie Z, Jin W
Carbohydrate polymers 2023 Nov 1;319:121174
Carbohydrate polymers 2023 Nov 1;319:121174
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Wang K, Li Z, Ding Y, Liu Z, Li Y, Liu X, Sun Y, Hong J, Zheng W, Qian L, Xu D
Journal of physiology and biochemistry 2023 May;79(2):341-353
Journal of physiology and biochemistry 2023 May;79(2):341-353
Silk Fibroin and Sericin Differentially Potentiate the Paracrine and Regenerative Functions of Stem Cells Through Multiomics Analysis.
Zhang Y, Sheng R, Chen J, Wang H, Zhu Y, Cao Z, Zhao X, Wang Z, Liu C, Chen Z, Zhang P, Kuang B, Zheng H, Shen C, Yao Q, Zhang W
Advanced materials (Deerfield Beach, Fla.) 2023 May;35(20):e2210517
Advanced materials (Deerfield Beach, Fla.) 2023 May;35(20):e2210517
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ding S, Jiang J, Zhang G, Yu M, Zheng Y
Ecotoxicology and environmental safety 2023 May;256:114897
Ecotoxicology and environmental safety 2023 May;256:114897
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
Chen H, Tao X, Cao H, Li B, Sun Q, Wang W, Zou Y, Mu M, Tao H, Zhao Y, Ge D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Xia G, Wen Z, Zhang L, Huang J, Wang X, Liang C, Cui X, Cao X, Wu S
Experimental gerontology 2023 May;175:112140
Experimental gerontology 2023 May;175:112140
Pilose antler extract restores type I and III collagen to accelerate wound healing.
Li L, Ma Y, He G, Ma S, Wang Y, Sun Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114510
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114510
GATA6 triggers fibroblast activation and tracheal fibrosis through the Wnt/β-catenin pathway.
Li A, Gu L, Mu J, Li Y, Wang X, Jiang J, Bai Y, Yang M, He C, Xiao R, Liao J, Jin X, Xiao M, Xiao Y, Zhang X, Tan T, Peng M, Xu L, Guo S
Cellular signalling 2023 May;105:110593
Cellular signalling 2023 May;105:110593
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis.
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W, Liao J
Genes & diseases 2023 May;10(3):1040-1054
Genes & diseases 2023 May;10(3):1040-1054
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
Hou XX, Li YW, Song JL, Zhang W, Liu R, Yuan H, Feng TT, Jiang ZY, Li WT, Zhu CL
World journal of gastroenterology 2023 May 7;29(17):2616-2627
World journal of gastroenterology 2023 May 7;29(17):2616-2627
KLF9 Promotes Osteogenic Differentiation of Dental Stem Cells by Negatively Regulating Notch1 Mediated Signaling Pathway.
Zhao X, Mai Z, Lu Y, Cui L, Yu J
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
Frontiers in bioscience (Landmark edition) 2023 May 6;28(5):85
Apatinib remodels the immunosuppressive tumor ecosystem of gastric cancer enhancing anti-PD-1 immunotherapy.
Luo Q, Dong Z, Xie W, Fu X, Lin L, Zeng Q, Chen Y, Ye G, Chen M, Hu H, Wang L, Xie Y, Cai W
Cell reports 2023 May 30;42(5):112437
Cell reports 2023 May 30;42(5):112437
Oleuropein-Rich Gellan Gum/Alginate Films as Innovative Treatments against Photo-Induced Skin Aging.
Busto F, Licini C, Luccarini A, Damiani E, Mattioli-Belmonte M, Cometa S, De Giglio E
Molecules (Basel, Switzerland) 2023 May 25;28(11)
Molecules (Basel, Switzerland) 2023 May 25;28(11)
Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α-sXBP1-GATA4 pathway.
Su H, Xu J, Su Z, Xiao C, Wang J, Zhong W, Meng C, Yang D, Zhu Y
Cellular and molecular life sciences : CMLS 2023 May 23;80(6):161
Cellular and molecular life sciences : CMLS 2023 May 23;80(6):161
Crosstalk between the JAK2 and TGF-β1 signaling pathways in scleroderma-related interstitial lung disease targeted by baricitinib.
Wang D, Wei Y, Xu L, Zhang J
Advances in rheumatology (London, England) 2023 May 16;63(1):22
Advances in rheumatology (London, England) 2023 May 16;63(1):22
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Xi T, Wang R, Pi D, Ouyang J, Yang J
Experimental cell research 2023 May 1;426(1):113556
Experimental cell research 2023 May 1;426(1):113556
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
Wang X, Jiang X, Li B, Zheng J, Guo J, Gao L, Du M, Weng X, Li L, Chen S, Zhang J, Fang L, Liu T, Wang L, Liu W, Neculai D, Sun Q
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
The role of interleukin 36γ in the epithelial-mesenchymal transition process of chronic rhinosinusitis: A pilot study.
Shen LF, Chen HH, Guo Y
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Mar;48(2):347-355
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Mar;48(2):347-355
Ginsenoside Re inhibits myocardial fibrosis by regulating miR-489/myd88/NF-κB pathway.
Sun J, Wang R, Chao T, Peng J, Wang C, Chen K
Journal of ginseng research 2023 Mar;47(2):218-227
Journal of ginseng research 2023 Mar;47(2):218-227
MetBil as a novel molecular regulator in ischemia-induced cardiac fibrosis via METTL3-mediated m6A modification.
Zhuang Y, Li T, Hu X, Xie Y, Pei X, Wang C, Li Y, Liu J, Tian Z, Zhang X, Peng L, Meng B, Wu H, Yuan W, Pan Z, Lu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Mar;37(3):e22797
m(6)A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis.
Chen L, Xia S, Wang F, Zhou Y, Wang S, Yang T, Li Y, Xu M, Zhou Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S
Pharmacological research 2023 Mar;189:106704
Pharmacological research 2023 Mar;189:106704
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling.
Pi L, Sun C, Jn-Simon N, Basha S, Thomas H, Figueroa V, Zarrinpar A, Cao Q, Petersen B
Journal of cell communication and signaling 2023 Mar;17(1):137-150
Journal of cell communication and signaling 2023 Mar;17(1):137-150
Herbal formula Jiawei Xiaochengqi decoction prevents postoperative abdominal adhesion in a rat model through inhibition of CXCL2-CXCR2 pathway.
Liu W, Wu F, Bi X, Hou L, Wang C, Li Y, Zeng Z, Xia C, Tang L, Hou C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154662
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Mar;111:154662
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
Wang S, Huang Z, Liu Y, Sun H, Zhou Y, Shi J
Translational lung cancer research 2023 Mar 31;12(3):427-445
Translational lung cancer research 2023 Mar 31;12(3):427-445
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Li Y, Xu W, Makova S, Brueckner M, Sun Z
eLife 2023 Mar 15;12
eLife 2023 Mar 15;12
Luteolin reduces cardiac damage caused by hyperlipidemia in Sprague-Dawley rats.
Dong M, Luo Y, Lan Y, He Q, Xu L, Pei Z
Heliyon 2023 Jun;9(6):e17613
Heliyon 2023 Jun;9(6):e17613
PCSK9 Inhibition Regulates Infarction-Induced Cardiac Myofibroblast Transdifferentiation via Notch1 Signaling.
Wu C, Lin D, Ji J, Jiang Y, Jiang F, Wang Y
Cell biochemistry and biophysics 2023 Jun;81(2):359-369
Cell biochemistry and biophysics 2023 Jun;81(2):359-369
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis.
Zhao Y, Fan X, Wang Q, Zhen J, Li X, Zhou P, Lang Y, Sheng Q, Zhang T, Huang T, Zhao Y, Lv Z, Wang R
Redox biology 2023 Jun;62:102674
Redox biology 2023 Jun;62:102674
Cartilage-like protein hydrogels engineered via entanglement.
Fu L, Li L, Bian Q, Xue B, Jin J, Li J, Cao Y, Jiang Q, Li H
Nature 2023 Jun;618(7966):740-747
Nature 2023 Jun;618(7966):740-747
TGF-β-induced PI3K/AKT/mTOR pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease.
Tang Q, Markby GR, MacNair AJ, Tang K, Tkacz M, Parys M, Phadwal K, MacRae VE, Corcoran BM
Cell proliferation 2023 Jun;56(6):e13435
Cell proliferation 2023 Jun;56(6):e13435
Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair.
Sun H, Xu J, Wang Y, Shen S, Xu X, Zhang L, Jiang Q
Bioactive materials 2023 Jun;24:477-496
Bioactive materials 2023 Jun;24:477-496
Continuously released Zn(2+) in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties.
Li C, Sun F, Tian J, Li J, Sun H, Zhang Y, Guo S, Lin Y, Sun X, Zhao Y
Bioactive materials 2023 Jun;24:361-375
Bioactive materials 2023 Jun;24:361-375
Hsa-miR-379 down-regulates Rac1/MLK3/JNK/AP-1/Collagen I cascade reaction by targeting connective tissue growth factor in human alveolar basal epithelial A549 cells.
Shan J, Wu MY, Zhang YC, Lin YJ, Cheng B, Gao YR, Liu ZH, Xu HM
Cytokine 2023 Jun;166:156191
Cytokine 2023 Jun;166:156191
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
Xu Q, Zhu W, Tang M, Zhang M, Liu Y, Li Z, Rao Z, He X, Ma R, Xue X
Cytokine 2023 Jun;166:156188
Cytokine 2023 Jun;166:156188
Liensinine prevents ischemic injury following myocardial infarction via inhibition of Wnt/β‑catenin signaling activation.
Shen F, Wu C, Zhong X, Ma E, Peng J, Zhu W, Wo D, Ren DN
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114675
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Sun Y, Weng J, Chen X, Ma S, Zhang Y, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Yu J, Zhao X, Yan X, Li W, Liu Y, Wang J, Wang J, Yang Y, Hao Y, Liang Z, Tao Y, Yuan Y, Du Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells.
Kong H, Song Q, Hu W, Guo S, Xiang D, Huang S, Xu X, He J, Pan L, Tao R, Yu H, Huang J
Parasites & vectors 2023 Jun 6;16(1):184
Parasites & vectors 2023 Jun 6;16(1):184
Wound Gel with Antimicrobial Effects Based on Polyvinyl Alcohol and Functional Aryloxycyclotriphosphazene.
Yudaev P, Butorova I, Chuev V, Posokhova V, Klyukin B, Chistyakov E
Polymers 2023 Jun 27;15(13)
Polymers 2023 Jun 27;15(13)
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
Wang R, Yang YM
World journal of cardiology 2023 Jun 26;15(6):293-308
World journal of cardiology 2023 Jun 26;15(6):293-308
Ginsenoside Rk3 Regulates Nonalcoholic Steatohepatitis by Modulation of Intestinal Flora and the PI3K/AKT Signaling Pathway in C57BL/6 Mice.
Guo M, Zhu C, Fu R, Ma X, Duan Z, Fan D
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
Journal of agricultural and food chemistry 2023 Jun 21;71(24):9370-9380
Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis.
Wang Y, Xiong L, Dong Z, Ran K, Bai W, Mo Z, Huang K, Ye Y, Tao Y, Yin S, Li M, He Q
ACS applied materials & interfaces 2023 Jun 21;15(24):28941-28953
ACS applied materials & interfaces 2023 Jun 21;15(24):28941-28953
RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse.
Chen Y, Tang R, Xiong W, Zhang F, Wang N, Xie B, Cao J, Chen Z, Ma C
Journal of translational medicine 2023 Jun 18;21(1):396
Journal of translational medicine 2023 Jun 18;21(1):396
Baicalin inhibited both the Furin/TGFβ1/Smad3/TSP-1 pathway in endothelial cells and the AKT/Ca(2+)/ROS pathway in platelets to ameliorate inflammatory coagulopathy.
Wang P, Wu J, Wang Q, Zhuang S, Zhao J, Yu Y, Zhang W, Zheng Y, Liu X
European journal of pharmacology 2023 Jun 15;949:175674
European journal of pharmacology 2023 Jun 15;949:175674
A seminal perspective on the role of chondroitin sulfate in biomineralization.
Hao JX, Wan QQ, Mu Z, Gu JT, Yu WW, Qin W, Li YT, Wang CY, Ma YX, Jiao K, Tay F, Niu L
Carbohydrate polymers 2023 Jun 15;310:120738
Carbohydrate polymers 2023 Jun 15;310:120738
Sparganii Rhizoma alleviates pulmonary fibrosis by inhibiting fibroblasts differentiation and epithelial-mesenchymal transition mediated by TGF-β1/ Smad2/3 pathway.
Liu J, Gao D, Ding Q, Zhang B, Zhu W, Shi Y
Journal of ethnopharmacology 2023 Jun 12;309:116305
Journal of ethnopharmacology 2023 Jun 12;309:116305
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse.
Guo T, Du Z, Wang XQ, Lang JH, Sun ZJ
Connective tissue research 2023 Jul;64(4):376-388
Connective tissue research 2023 Jul;64(4):376-388
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1.
Wang S, Qu Y, Fang X, Ding Q, Zhao H, Yu X, Xu T, Lu R, Jing S, Liu C, Wu H, Liu Y
Experimental & molecular medicine 2023 Jul;55(7):1413-1423
Experimental & molecular medicine 2023 Jul;55(7):1413-1423
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Wei S, Cheng X, Li J, Zhai K, Huang J, Wang S, Li Y, Liu D
Artificial organs 2023 Jul;47(7):1163-1173
Artificial organs 2023 Jul;47(7):1163-1173
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Ren G, Lv W, Ding Y, Wang L, Cui Z, Li R, Tian J, Zhang C
Journal of ginseng research 2023 Jul;47(4):543-551
Journal of ginseng research 2023 Jul;47(4):543-551
3D Printed Biomimetic Metamaterials with Graded Porosity and Tapering Topology for Improved Cell Seeding and Bone Regeneration.
Zhang L, Wang B, Song B, Yao Y, Choi SK, Yang C, Shi Y
Bioactive materials 2023 Jul;25:677-688
Bioactive materials 2023 Jul;25:677-688
Neotuberostemonine and tuberostemonine ameliorate pulmonary fibrosis through suppressing TGF-β and SDF-1 secreted by macrophages and fibroblasts via the PI3K-dependent AKT and ERK pathways.
Fu S, Song X, Hu Y, Zhu Q, Lv X, Tang X, Zhang M
Chinese journal of natural medicines 2023 Jul;21(7):527-539
Chinese journal of natural medicines 2023 Jul;21(7):527-539
hUMSCs Transplantation Regulates AMPK/NR4A1 Signaling Axis to Inhibit Ovarian Fibrosis in POI Rats.
Cui L, Bao H, Zhu W, Tang Y, Luo Q, Si Y, Fu Q, Jiang Z
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Stem cell reviews and reports 2023 Jul;19(5):1449-1465
Inhaled Lipid Nanoparticles Alleviate Established Pulmonary Fibrosis.
Li D, Zhao A, Zhu J, Wang C, Shen J, Zheng Z, Pan F, Liu Z, Chen Q, Yang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Jul;19(30):e2300545
Small (Weinheim an der Bergstrasse, Germany) 2023 Jul;19(30):e2300545
Sacha inchi albumin delays skin-aging by alleviating inflammation, oxidative stress and regulating gut microbiota in d-galactose induced-aging mice.
Zeng J, An M, Tian W, Wang K, Du B, Li P
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
Journal of the science of food and agriculture 2023 Jul;103(9):4470-4480
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Ai C, Sun X, Xiao S, Guo L, Shang M, Shi D, Meng D, Zhao Y, Wang X, Li J
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Odontoblasts release exosomes to regulate the odontoblastic differentiation of dental pulp stem cells.
Luo X, Feng W, Huang S, Miao S, Jiang T, Lei Q, Yin J, Zhang S, Bai X, Hao C, Li W, Ma D
Stem cell research & therapy 2023 Jul 8;14(1):176
Stem cell research & therapy 2023 Jul 8;14(1):176
Metformin attenuates chronic lung allograft dysfunction: evidence in rat models.
Tian D, Zheng X, Tang H, Huang H, Wang J, Xu L, Li C, Yan H, Yu R, Nan J, Liu M, Guo X, Jian S, Wang T, Deng S, Pu Q, Liu L
Respiratory research 2023 Jul 29;24(1):192
Respiratory research 2023 Jul 29;24(1):192
CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function.
Yin Y, Mu C, Wang J, Wang Y, Hu W, Zhu W, Yu X, Hao W, Zheng Y, Li Q, Han W
Toxics 2023 Jul 26;11(8)
Toxics 2023 Jul 26;11(8)
Echinacoside-Zinc Nanomaterial Inhibits Skin Glycation by Suppressing the Transcriptional Activation of the Receptor for Advanced Glycation End-Products.
Han J, Sun Y, Wu T, Hou X, Zheng S, Zhang H, Lin T, Liu H, Sun T
ACS nano 2023 Jul 25;17(14):14123-14135
ACS nano 2023 Jul 25;17(14):14123-14135
Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice.
Han MM, He XY, Tang L, Qi L, Yang MY, Wang Y, Xing L, Jeong JH, Jiang HL
Science advances 2023 Jul 21;9(29):eadg5358
Science advances 2023 Jul 21;9(29):eadg5358
Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH.
Yao S, Zhou Z, Wang L, Lv H, Liu D, Zhu Q, Zhang X, Zhao G, Hu Y
iScience 2023 Jul 21;26(7):107201
iScience 2023 Jul 21;26(7):107201
Different exercise training intensities prevent type 2 diabetes mellitus-induced myocardial injury in male mice.
Pei Z, Zhou R, Yao W, Dong S, Liu Y, Gao Z
iScience 2023 Jul 21;26(7):107080
iScience 2023 Jul 21;26(7):107080
Triptolide with hepatotoxicity and nephrotoxicity used in local delivery treatment of myocardial infarction by thermosensitive hydrogel.
Wang K, Zhu K, Zhu Z, Shao F, Qian R, Wang C, Dong H, Li Y, Gao Z, Zhao J
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Journal of nanobiotechnology 2023 Jul 17;21(1):227
Crystalline silica-induced macrophage pyroptosis interacting with mitophagy contributes to pulmonary fibrosis via modulating mitochondria homeostasis.
Wei Y, You Y, Zhang J, Ban J, Min H, Li C, Chen J
Journal of hazardous materials 2023 Jul 15;454:131562
Journal of hazardous materials 2023 Jul 15;454:131562
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Ge Y, Hu D, Xi Y, Wang H, Xia T, Chen J, Pu X, Xiao H
Life sciences 2023 Jul 15;325:121767
Life sciences 2023 Jul 15;325:121767
Gypenosides suppress fibrosis of the renal NRK-49F cells by targeting miR-378a-5p through the PI3K/AKT signaling pathway.
Zhang L, Wang X, He S, Zhang F, Li Y
Journal of ethnopharmacology 2023 Jul 15;311:116466
Journal of ethnopharmacology 2023 Jul 15;311:116466
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Lv J, Zhang R, Li D, Liu Y
Functional & integrative genomics 2023 Jul 14;23(3):241
Functional & integrative genomics 2023 Jul 14;23(3):241
Instantaneous self-healing and strongly adhesive self-adaptive hyaluronic acid-based hydrogel for controlled drug release to promote tendon wound healing.
Ren Z, Duan Z, Zhang Z, Fu R, Zhu C, Fan D
International journal of biological macromolecules 2023 Jul 1;242(Pt 2):125001
International journal of biological macromolecules 2023 Jul 1;242(Pt 2):125001
Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation.
Wang MX, Luo W, Ye L, Jin LM, Yang B, Zhang QH, Qian JC, Wang Y, Zhang Y, Liang G
Acta pharmacologica Sinica 2023 Jan;44(1):120-132
Acta pharmacologica Sinica 2023 Jan;44(1):120-132
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
IKKα aggravates renal fibrogenesis by positively regulating the Wnt/β-catenin pathway.
Zhang H, Pan B, Huang W, Ma M, Zhang F, Jiang L, Qian C, Wan X, Cao C
Immunology 2023 Jan;168(1):120-134
Immunology 2023 Jan;168(1):120-134
Differentiation ability of Gli1(+) cells during orthodontic tooth movement.
Seki Y, Takebe H, Mizoguchi T, Nakamura H, Iijima M, Irie K, Hosoya A
Bone 2023 Jan;166:116609
Bone 2023 Jan;166:116609
The combination of exercise and metformin inhibits TGF-β1/Smad pathway to attenuate myocardial fibrosis in db/db mice by reducing NF-κB-mediated inflammatory response.
Liu J, Lu J, Zhang L, Liu Y, Zhang Y, Gao Y, Yuan X, Xiang M, Tang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114080
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jan;157:114080
The aggravate role of exosomal circRNA11:120406118|12040782 on macrophage pyroptosis through miR-30b-5p/NLRP3 axis in silica-induced lung fibrosis.
Zhang Q, Ban J, Chang S, Qu H, Chen J, Liu F
International immunopharmacology 2023 Jan;114:109476
International immunopharmacology 2023 Jan;114:109476
Sodium houttuyfonate against cardiac fibrosis attenuates isoproterenol-induced heart failure by binding to MMP2 and p38.
Tan R, You Q, Cui J, Wang M, Song N, An K, Lin L, Adu-Amankwaah J, Yuan J, Sun H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154590
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154590
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Chen C, Sun S, Zhao J, Wu Q, He W, Sun W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
Li H, Cui H, Ren J, Wang D, Zhao R, Zhu S, Liu S, Liu X, Tian S, Zhang Y, Zhao P, Li P, Thorne RF, Duan S
Cell transplantation 2023 Jan-Dec;32:9636897231162526
Cell transplantation 2023 Jan-Dec;32:9636897231162526
Cannabidiol Rescues TNF-α-Inhibited Proliferation, Migration, and Osteogenic/Odontogenic Differentiation of Dental Pulp Stem Cells.
Yu L, Zeng L, Zhang Z, Zhu G, Xu Z, Xia J, Weng J, Li J, Pathak JL
Biomolecules 2023 Jan 6;13(1)
Biomolecules 2023 Jan 6;13(1)
7,8-Dihydroxyflavone alleviates cardiac fibrosis by restoring circadian signals via downregulating Bmal1/Akt pathway.
Hang PZ, Liu J, Wang JP, Li FF, Li PF, Kong QN, Shi J, Ji HY, Du ZM, Zhao J
European journal of pharmacology 2023 Jan 5;938:175420
European journal of pharmacology 2023 Jan 5;938:175420
Epigenetic control of LncRNA NEAT1 enables cardiac fibroblast pyroptosis and cardiac fibrosis.
Ding JF, Zhou Y, Xu SS, Shi KH, Sun H, Tu B, Song K, Xuan HY, Sha JM, Zhao JY, Tao H
European journal of pharmacology 2023 Jan 5;938:175398
European journal of pharmacology 2023 Jan 5;938:175398
Promotion of the genipin crosslinked chitosan-fiber hydrogel loaded with sustained release of clemastine fumarate in diabetic wound repair.
Zuo R, Shi J, Jiang S, Chu M, Wang Q, Kong L, Kang Q, Guo Y, Guan J
International journal of biological macromolecules 2023 Jan 31;226:900-914
International journal of biological macromolecules 2023 Jan 31;226:900-914
Berberin sustained-release nanoparticles were enriched in infarcted rat myocardium and resolved inflammation.
Zhu K, Yao Y, Wang K, Shao F, Zhu Z, Song Y, Zhou Z, Jiang D, Lan X, Qin C
Journal of nanobiotechnology 2023 Jan 28;21(1):33
Journal of nanobiotechnology 2023 Jan 28;21(1):33
Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease.
Cao Y, Cheng K, Yang M, Deng Z, Ma Y, Yan X, Zhang Y, Jia Z, Wang J, Tu K, Liang J, Zhang M
Journal of nanobiotechnology 2023 Jan 19;21(1):21
Journal of nanobiotechnology 2023 Jan 19;21(1):21
Irisin ameliorates D-galactose-induced skeletal muscle fibrosis via the PI3K/Akt pathway.
Wu Y, Wu Y, Yu J, Zhang Y, Li Y, Fu R, Sun Y, Zhao K, Xiao Q
European journal of pharmacology 2023 Jan 15;939:175476
European journal of pharmacology 2023 Jan 15;939:175476
Alamandine/MrgD axis prevents TGF-β1-mediated fibroblast activation via regulation of aerobic glycolysis and mitophagy.
Wang W, Zhang Y, Huang W, Yuan Y, Hong Q, Xie Z, Li L, Chen Y, Li X, Meng Y
Journal of translational medicine 2023 Jan 13;21(1):24
Journal of translational medicine 2023 Jan 13;21(1):24
Macrophage-derived exosomal lncRNA MSTRG.91634.7 inhibits fibroblasts activation by targeting PINK1 in silica-induced lung fibrosis.
Ban J, Liu F, Zhang Q, Chang S, Zeng X, Chen J
Toxicology letters 2023 Jan 1;372:36-44
Toxicology letters 2023 Jan 1;372:36-44
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H
Journal of periodontology 2023 Feb;94(2):277-289
Journal of periodontology 2023 Feb;94(2):277-289
Metformin enhances the osteogenic activity of rat bone marrow mesenchymal stem cells by inhibiting oxidative stress induced by diabetes mellitus: an in vitro and in vivo study.
Dong K, Zhou WJ, Liu ZH
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Journal of periodontal & implant science 2023 Feb;53(1):54-68
Toll-like receptor-2 in cardiomyocytes and macrophages mediates isoproterenol-induced cardiac inflammation and remodeling.
Qian J, Liang S, Wang Q, Xu J, Huang W, Wu G, Liang G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22740
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22740
Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.
Kim M, Kruhlak M, Hoffmann V, Zerfas P, Bishop K, Doolittle WKL, Edmondson EF, Zhu YJ, Cheng SY
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250
Mechanism of YY1 mediating autophagy dependent ferroptosis in PM2.5 induced cardiac fibrosis.
Hu H, Li L, Zhang H, Zhang Y, Liu Q, Chen M, Ning J, Pang Y, Hu W, Niu Y, Zhang R
Chemosphere 2023 Feb;315:137749
Chemosphere 2023 Feb;315:137749
Hyperlipidemia impacts osteogenesis via lipophagy.
Ji C, Zhang Z, Xu X, Song D, Zhang D
Bone 2023 Feb;167:116643
Bone 2023 Feb;167:116643
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
Shi X, Wu Y, Ni H, Li M, Qi B, Xu Y
International immunopharmacology 2023 Feb;115:109600
International immunopharmacology 2023 Feb;115:109600
A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice.
Jin L, Wang M, Yang B, Ye L, Zhu W, Zhang Q, Lou S, Zhang Y, Luo W, Liang G
International immunopharmacology 2023 Feb;115:109587
International immunopharmacology 2023 Feb;115:109587
Loss of Protein Kinase D2 Activity Protects Against Bleomycin-Induced Dermal Fibrosis in Mice.
Chen L, Zhao J, Chao Y, Roy A, Guo W, Qian J, Xu W, Domsic RT, Lafyatis R, Lu B, Deng F, Wang QJ
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100018
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100018
Naringenin is a Potential Immunomodulator for Inhibiting Liver Fibrosis by Inhibiting the cGAS-STING Pathway.
Chen L, Xia S, Wang S, Zhou Y, Wang F, Li Z, Li Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S
Journal of clinical and translational hepatology 2023 Feb 28;11(1):26-37
Journal of clinical and translational hepatology 2023 Feb 28;11(1):26-37
Stimulus-Responsive Zwitterionic Prodrug Delivery System with Sustained Release of Hydrogen Sulfide for Protective Aortic Dissection.
Ren B, Liu R, He Q, Wu T, Song L, Wang H, Gu J
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
ACS applied materials & interfaces 2023 Feb 22;15(7):9099-9109
Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia-reperfusion injury.
Li X, Guo L, Wang J, Yang X
European journal of medical research 2023 Feb 20;28(1):84
European journal of medical research 2023 Feb 20;28(1):84
FNDC5/Irisin Inhibits the Inflammatory Response and Mediates the Aerobic Exercise-Induced Improvement of Liver Injury after Myocardial Infarction.
Wang T, Yu M, Li H, Qin S, Ren W, Ma Y, Bo W, Xi Y, Cai M, Tian Z
International journal of molecular sciences 2023 Feb 19;24(4)
International journal of molecular sciences 2023 Feb 19;24(4)
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
Dong H, Han X, Hao M, Yang Q, Lyu Q, Tang D, Shen Z, Wang K, Kuang H, Cao G, Peng M, Shao M
Communications biology 2023 Feb 16;6(1):184
Communications biology 2023 Feb 16;6(1):184
C1Q labels a highly aggressive macrophage-like leukemia population indicating extramedullary infiltration and relapse.
Yang LX, Zhang CT, Yang MY, Zhang XH, Liu HC, Luo CH, Jiang Y, Wang ZM, Yang ZY, Shi ZP, Yang YC, Wei RQ, Zhou L, Mi J, Zhou AW, Yao ZR, Xia L, Yan JS, Lu Y
Blood 2023 Feb 16;141(7):766-786
Blood 2023 Feb 16;141(7):766-786
Albumin-Based Silibinin Nanocrystals Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy.
Luo S, Yang Y, Zhao T, Zhang R, Fang C, Li Y, Zhang Z, Gong T
ACS applied materials & interfaces 2023 Feb 15;15(6):7747-7758
ACS applied materials & interfaces 2023 Feb 15;15(6):7747-7758
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Hu Y, Jiang H, Xu Y, Chen G, Fan R, Zhou Y, Liu Y, Yao Y, Liu R, Chen W, Zhang K, Chen X, Wang R, Qiu Z
Cell death discovery 2023 Feb 14;9(1):63
Cell death discovery 2023 Feb 14;9(1):63
Deciphering the underlying wound healing mechanisms of Streptocaulon juventas (Lour.) Merr. by integrating network pharmacology, transcriptomics, and experimental validation.
Li Y, Zang J, Wang X, Feng X, Qiu F
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115890
Journal of ethnopharmacology 2023 Feb 10;302(Pt A):115890
Lactoferrin attenuated urban particulate matter-induced nephrotoxicity by regulating the CSF2/CENPE axis.
Liu WC, Chiu HW, Chou CL, Chiu YJ, Lee YH
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120871
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120871
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207
Tissue & cell 2023 Dec;85:102207
Nanomechanical-based classification of prostate tumor using atomic force microscopy.
Zeng J, Zhang Y, Xu R, Chen H, Tang X, Zhang S, Yang H
The Prostate 2023 Dec;83(16):1591-1601
The Prostate 2023 Dec;83(16):1591-1601
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Yuan T, Xia Y, Pan S, Li B, Ye Z, Yan X, Hu W, Li L, Song B, Yu W, Li H, Rao T, Lin F, Zhou X, Cheng F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Design of a Haversian system-like gradient porous scaffold based on triply periodic minimal surfaces for promoting bone regeneration.
Li L, Wang P, Liang H, Jin J, Zhang Y, Shi J, Zhang Y, He S, Mao H, Xue B, Lai J, Zhu L, Jiang Q
Journal of advanced research 2023 Dec;54:89-104
Journal of advanced research 2023 Dec;54:89-104
LPS-induced macrophage exosomes promote the activation of hepatic stellate cells and the intervention study of total astragalus saponins combined with glycyrrhizic acid.
Deng K, Dai Z, Yang P, Yang D, Zhou Y
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3097-3105
Anatomical record (Hoboken, N.J. : 2007) 2023 Dec;306(12):3097-3105
Inhaled pulmonary surfactant biomimetic liposomes for reversing idiopathic pulmonary fibrosis through synergistic therapeutic strategy.
Wang B, Gao Y, Sun L, Xue M, Wang M, Zhang Z, Zhang L, Zhang H
Biomaterials 2023 Dec;303:122404
Biomaterials 2023 Dec;303:122404
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Yang J, Shi X, Gao R, Fan L, Chen R, Cao Y, Xu T, Yang J
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Electrospun sandwich mesh structures loaded with naringenin and vitamin K(2) polycaprolactone/gelatin nanofibers synergistically promote bone regeneration.
Wang J, Shao L, Wu X, Liu C, Ni S, Dai T, Liu H, Zhao H
Materials today. Bio 2023 Dec;23:100794
Materials today. Bio 2023 Dec;23:100794
Anthelmintic nitazoxanide protects against experimental pulmonary fibrosis.
Chen XY, Dong YC, Yu YY, Jiang M, Bu WJ, Li P, Sun ZJ, Dong DL
British journal of pharmacology 2023 Dec;180(23):3008-3023
British journal of pharmacology 2023 Dec;180(23):3008-3023
Expression and function of CCN2-derived circRNAs in chondrocytes.
Kato S, Kawata K, Nishida T, Mizukawa T, Takigawa M, Iida S, Kubota S
Journal of cell communication and signaling 2023 Dec;17(4):1501-1515
Journal of cell communication and signaling 2023 Dec;17(4):1501-1515
Pancreatic Acinar Cells-Derived Sphingosine-1-Phosphate Contributes to Fibrosis of Chronic Pancreatitis via Inducing Autophagy and Activation of Pancreatic Stellate Cells.
Wang D, Han S, Lv G, Hu Y, Zhuo W, Zeng Z, Tang J, Huang Y, Wang F, Wang J, Zhao Y, Zhao G
Gastroenterology 2023 Dec;165(6):1488-1504.e20
Gastroenterology 2023 Dec;165(6):1488-1504.e20
Diabetic and nondiabetic BMSC-derived exosomes affect bone regeneration via regulating miR-17-5p/SMAD7 axis.
Li Z, Zhang B, Shang J, Wang Y, Jia L, She X, Xu X, Zhang D, Guo J, Zhang F
International immunopharmacology 2023 Dec;125(Pt B):111190
International immunopharmacology 2023 Dec;125(Pt B):111190
BMAL1 inhibits renal fibrosis and renal interstitial inflammation by targeting the ERK1/2/ELK-1/Egr-1 axis.
Chen W, Zhao S, Xing J, Yu W, Rao T, Zhou X, Ruan Y, Li S, Xia Y, Song T, Zou F, Li W, Cheng F
International immunopharmacology 2023 Dec;125(Pt B):111140
International immunopharmacology 2023 Dec;125(Pt B):111140
Activation of cGAS-STING signaling pathway promotes liver fibrosis and hepatic sinusoidal microthrombosis.
Luo S, Luo R, Lu H, Zhang R, Deng G, Luo H, Yu X, Wang C, Zhang H, Zhang Y, Huang W, Sun J, Liu Y, Huang F, Lei Z
International immunopharmacology 2023 Dec;125(Pt B):111132
International immunopharmacology 2023 Dec;125(Pt B):111132
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
He C, Wang W, Wei G, Wang Y, Wei Y, Wang J, Zhang Z
International immunopharmacology 2023 Dec;125(Pt A):111144
International immunopharmacology 2023 Dec;125(Pt A):111144
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Bao S, Chen T, Chen J, Zhang J, Zhang G, Hui Y, Li J, Yan S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Liu C, Zhao M, Chen J, Xu L, Wang K, Li G
European journal of pharmacology 2023 Dec 5;960:176121
European journal of pharmacology 2023 Dec 5;960:176121
TRIOBP modulates β-catenin signaling by regulation of miR-29b in idiopathic pulmonary fibrosis.
Wang L, Zhao W, Xia C, Ma S, Li Z, Wang N, Ding L, Wang Y, Cheng L, Liu H, Yang J, Li Y, Rosas I, Yu G
Cellular and molecular life sciences : CMLS 2023 Dec 29;81(1):13
Cellular and molecular life sciences : CMLS 2023 Dec 29;81(1):13
Effect of a New Hyaluronic Acid Hydrogel Dermal Filler Cross-Linked With Lysine Amino Acid for Skin Augmentation and Rejuvenation.
Guo Y, Wei W, Wang H, Li Q, Wei C, Zhang J, Jin P
Aesthetic surgery journal 2023 Dec 14;44(1):NP87-NP97
Aesthetic surgery journal 2023 Dec 14;44(1):NP87-NP97
The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis.
Zhu Y, Kang A, Kuai Y, Guo Y, Miao X, Zhu L, Kong M, Li N
Cell death & disease 2023 Dec 14;14(12):826
Cell death & disease 2023 Dec 14;14(12):826
Aloin Attenuates Oxidative Stress, Inflammation, and CCl(4)-Induced Liver Fibrosis in Mice: Possible Role of TGF-β/Smad Signaling.
Bai J, Qian B, Cai T, Chen Y, Li T, Cheng Y, Wu Z, Liu C, Ye M, Du Y, Fu W
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Journal of agricultural and food chemistry 2023 Dec 13;71(49):19475-19487
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Liu D, Song Y, Chen H, You Y, Zhu L, Zhang J, Xu X, Hu J, Huang X, Wu X, Xu X, Jiang S, Du Y
Nature communications 2023 Dec 13;14(1):8268
Nature communications 2023 Dec 13;14(1):8268
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Wang P, Zhuang W, Zheng Z, Zhang L, Zhang X, Chen Q
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
The application of a novel platform of multiparametric magnetic resonance imaging in a bioenvironmental toxic carbon tetrachloride-induced mouse model of liver fibrosis.
Qiuling L, Qilin Y, Cheng Y, Minping Z, Kangning W, Enhua X
Environmental research 2023 Dec 1;238(Pt 1):117130
Environmental research 2023 Dec 1;238(Pt 1):117130
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Wang L, Yu X, Li H, He D, Zeng S, Xiang Z
Chinese medicine 2023 Dec 1;18(1):158
Chinese medicine 2023 Dec 1;18(1):158
AP-1 signaling modulates cardiac fibroblast stress responses.
Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ
Journal of cell science 2023 Dec 1;136(23)
Journal of cell science 2023 Dec 1;136(23)
Sirt1 Overexpression Inhibits Fibrous Scar Formation and Improves Functional Recovery After Cerebral Ischemic Injury Through the Deacetylation of 14-3-3ζ.
Chen Y, Huang J, Liu J, Zhu H, Li X, Wen J, Tian M, Ren J, Zhou L, Yang Q
Molecular neurobiology 2023 Aug;60(8):4795-4810
Molecular neurobiology 2023 Aug;60(8):4795-4810
SCNN1B regulates the proliferation, migration, and collagen deposition of human lung fibroblasts.
Yan Y, Zhang Y, Zhang J, Ying L
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
In vitro cellular & developmental biology. Animal 2023 Aug;59(7):479-485
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Sustained release of magnesium and zinc ions synergistically accelerates wound healing.
Yang F, Xue Y, Wang F, Guo D, He Y, Zhao X, Yan F, Xu Y, Xia D, Liu Y
Bioactive materials 2023 Aug;26:88-101
Bioactive materials 2023 Aug;26:88-101
TSLP/TSLPR promotes renal fibrosis by activating STAT3 in renal fibroblasts.
Wang D, Wang F, Huang Y, Wang J, Luo H, Zhang P, Peng J, Tang G, Wang Y, Yu L, Ni D
International immunopharmacology 2023 Aug;121:110430
International immunopharmacology 2023 Aug;121:110430
Tough Gelatin Hydrogel for Tissue Engineering.
Yuan X, Zhu Z, Xia P, Wang Z, Zhao X, Jiang X, Wang T, Gao Q, Xu J, Shan D, Guo B, Yao Q, He Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301665
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Aug;10(24):e2301665
Tissue pleiotropic effect of biotin and prebiotic supplementation in established obesity.
Voland L, Yuan M, Lecoutre S, Debédat J, Pelloux V, Pradeau M, Coles E, Merabtene F, Zhang C, Mardinoglu A, Le Roy T, Soula H, Clément K
American journal of physiology. Endocrinology and metabolism 2023 Aug 30;
American journal of physiology. Endocrinology and metabolism 2023 Aug 30;
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Su H, Zhang C
Journal of translational medicine 2023 Aug 2;21(1):521
Journal of translational medicine 2023 Aug 2;21(1):521
Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway.
Zhang B, Li X, Zhou X, Lou C, Wang S, Lv H, Zhang G, Fang Y, Yin D, Shang P
iScience 2023 Aug 18;26(8):107365
iScience 2023 Aug 18;26(8):107365
Transcriptomics Reveals Molecular Features of the Bilateral Pelvic Nerve Injury Rat Model of Detrusor Underactivity.
Wang J, Ren L, Liu X, Xu W, Liu M, Hu P, Wang T, Liu J, Ling Q
Biomolecules 2023 Aug 18;13(8)
Biomolecules 2023 Aug 18;13(8)
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism.
Hou X, Li Y, Song J, Peng L, Zhang W, Liu R, Yuan H, Feng T, Li J, Li W, Zhu C
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration.
Hertig V, Villeneuve L, Calderone A
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C496-C508
American journal of physiology. Cell physiology 2023 Aug 1;325(2):C496-C508
Aristolochic acid I exposure triggers ovarian dysfunction by activating NLRP3 inflammasome and affecting mitochondrial homeostasis.
Sun MX, Qiao FX, Xu ZR, Liu YC, Xu CL, Wang HL, Qi ZQ, Liu Y
Free radical biology & medicine 2023 Aug 1;204:313-324
Free radical biology & medicine 2023 Aug 1;204:313-324
Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway.
Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Apr;72(4):879-892
Changes in N6-methyladenosine RNA methylomes of human periodontal ligament cells in response to inflammatory conditions.
Zou X, Liu C, Wu X, Yuan Z, Yan F
Journal of periodontal research 2023 Apr;58(2):444-455
Journal of periodontal research 2023 Apr;58(2):444-455
Relaxin-2 Prevents Erectile Dysfunction by Cavernous Nerve, Endothelial and Histopathological Protection Effects in Rats with Bilateral Cavernous Nerve Injury.
Liu K, Sun T, Xu W, Song J, Chen Y, Ruan Y, Li H, Cui K, Zhang Y, Feng Y, Pan J, Liang E, Xin Z, Wang T, Wang S, Liu J, Luan Y
The world journal of men's health 2023 Apr;41(2):434-445
The world journal of men's health 2023 Apr;41(2):434-445
Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti-Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis.
Li F, Zhao Y, Cheng Z, Wang Y, Yue Y, Cheng X, Sun J, Atabakhshi-Kashi M, Yao J, Dou J, Yu J, Zhang X, Qi Y, Li X, Qi X, Nie G
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(17):e2212206
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(17):e2212206
Deficiency of HtrA3 Attenuates Bleomycin-Induced Pulmonary Fibrosis Via TGF-β1/Smad Signaling Pathway.
Li G, Shen C, Wei D, Yang X, Jiang C, Yang X, Mao W, Zou J, Tan J, Chen J
Lung 2023 Apr;201(2):235-242
Lung 2023 Apr;201(2):235-242
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
Hao M, Yao Z, Zhao M, Chen Z, Wang P, Sang X, Yang Q, Wang K, Han X, Cao G
Journal of ethnopharmacology 2023 Apr 6;305:116111
Journal of ethnopharmacology 2023 Apr 6;305:116111
PDGFBB improved the biological function of menstrual blood-derived stromal cells and the anti-fibrotic properties of exosomes.
Zhang X, Zhang S, Qi J, Zhao F, Lu Y, Li S, Wu S, Li P, Tan J
Stem cell research & therapy 2023 Apr 28;14(1):113
Stem cell research & therapy 2023 Apr 28;14(1):113
Stiffness-dependent dynamic effect of inflammation on keratocyte phenotype and differentiation.
Chen J, Mo Q, Sheng R, Long Q, Chen Z, Liu C, Zhang A, Luo Y, Liu J, Zhang W
Biomedical materials (Bristol, England) 2023 Apr 27;18(4)
Biomedical materials (Bristol, England) 2023 Apr 27;18(4)
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Zhang Y, Fu J, Han Y, Feng D, Yue S, Zhou Y, Luo Z
Biomedicines 2023 Apr 26;11(5)
Biomedicines 2023 Apr 26;11(5)
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Wang Y, Gao J, Sun L, Li Q, Kang N, Gao C, Li T
Journal of ethnopharmacology 2023 Apr 24;306:116180
Journal of ethnopharmacology 2023 Apr 24;306:116180
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050
Journal of ethnopharmacology 2023 Apr 24;306:116050
Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex.
Aoyama S, Kido Y, Kanamoto M, Naito M, Nakanishi M, Kanna M, Yamamotoya T, Asano T, Nakatsu Y
Experimental cell research 2023 Apr 15;425(2):113544
Experimental cell research 2023 Apr 15;425(2):113544
Metformin Collaborates with PINK1/Mfn2 Overexpression to Prevent Cardiac Injury by Improving Mitochondrial Function.
Ma Z, Liu Z, Li X, Zhang H, Han D, Xiong W, Zhou H, Yang X, Zeng Q, Ren H, Xu D
Biology 2023 Apr 11;12(4)
Biology 2023 Apr 11;12(4)
GL-V9 ameliorates liver fibrosis by inhibiting TGF-β/smad pathway.
Guo Y, Tian G, Chen X, Hou Y, Zhang X, Xue X, Zhao L, Wu Y
Experimental cell research 2023 Apr 1;425(1):113521
Experimental cell research 2023 Apr 1;425(1):113521
Suppression of SMOC2 alleviates myocardial fibrosis via the ILK/p38 pathway.
Rui H, Zhao F, Yuhua L, Hong J
Frontiers in cardiovascular medicine 2022;9:951704
Frontiers in cardiovascular medicine 2022;9:951704
Research on the Mechanism and Prevention of Hypertension Caused by Apatinib Through the RhoA/ROCK Signaling Pathway in a Mouse Model of Gastric Cancer.
Wang W, He Q, Li C, Zhuang C, Zhang H, Wang Q, Fan X, Qi M, Sun R, Yu J
Frontiers in cardiovascular medicine 2022;9:873829
Frontiers in cardiovascular medicine 2022;9:873829
Using Collagen Peptides From the Skin of Monkfish (Lophius litulon) to Ameliorate Kidney Damage in High-Fat Diet Fed Mice by Regulating the Nrf2 Pathway and NLRP3 Signaling.
Miao B, Zheng J, Zheng G, Tian X, Zhang W, Yuan F, Yang Z
Frontiers in nutrition 2022;9:798708
Frontiers in nutrition 2022;9:798708
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
Wang M, Zhao M, Yu J, Xu Y, Zhang J, Liu J, Zheng Z, Ye J, Wang Z, Ye D, Feng Y, Xu S, Pan W, Wei C, Wan J
Frontiers in cardiovascular medicine 2022;9:727474
Frontiers in cardiovascular medicine 2022;9:727474
CIDEC: A Potential Factor in Diabetic Vascular Inflammation.
Song FQ, Zhou HM, Ma WX, Li YL, Hu BA, Shang YY, Wang ZH, Zhong M, Zhang W, Ti Y
Journal of vascular research 2022;59(2):114-123
Journal of vascular research 2022;59(2):114-123
Loureirin A Exerts Antikeloid Activity by Antagonizing the TGF-β1/Smad Signalling Pathway.
Ma H, Duan X, Zhang R, Li H, Guo Y, Tian Y, Huang M, Chen G, Wang Z, Li L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8661288
Network Pharmacology Prediction and Molecular Docking-Based Strategy to Discover the Potential Pharmacological Mechanism of Wen-Yu-Jin against Pulmonary Fibrosis in a Mouse Model.
Wang L, Zhu W, Sun R, Liu J, Ma Q, Zhang B, Shi Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7753508
Evidence-based complementary and alternative medicine : eCAM 2022;2022:7753508
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Zou X, Li T, Mao Y, Zhu M, Chen X, Niu J, Dong T, Jiang J, Yang X
BioMed research international 2022;2022:6441179
BioMed research international 2022;2022:6441179
Therapeutic Potential of Synthetic Human β-Defensin 1 Short Motif Pep-B on Lipopolysaccharide-Stimulated Human Dental Pulp Stem Cells.
Shi J, Hu Z, Zhou Y, Zuo M, Wu H, Jin W, Xie Z
Mediators of inflammation 2022;2022:6141967
Mediators of inflammation 2022;2022:6141967
Shenxian-Shengmai Oral Liquid Evoke Autophagy of Fibroblast to Attenuate Sinoatrial Node Fibrosis in Sick Sinus Syndrome Mice via the AKT/mTOR Pathway.
Chen C, Zhang H, Hou S, Liu Y, Ren L, Hao M, Chen K, Li L, Cai X, Deng Z, Liu Z, Hou P
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5219277
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5219277
Mechanism of Action of Zhi Gan Cao Decoction for Atrial Fibrillation and Myocardial Fibrosis in a Mouse Model of Atrial Fibrillation: A Network Pharmacology-Based Study.
Gao L, Kan C, Chen X, Xu S, Shi K
Computational and mathematical methods in medicine 2022;2022:4525873
Computational and mathematical methods in medicine 2022;2022:4525873
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L, Fan C, Wang G, Gu X, Lin J
Oxidative medicine and cellular longevity 2022;2022:3415528
Oxidative medicine and cellular longevity 2022;2022:3415528
Silencing of TLR4 Inhibits Atrial Fibrosis and Susceptibility to Atrial Fibrillation via Downregulation of NLRP3-TGF-β in Spontaneously Hypertensive Rats.
Ge C, Zhao Y, Liang Y, He Y
Disease markers 2022;2022:2466150
Disease markers 2022;2022:2466150
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1247806
Oxidative medicine and cellular longevity 2022;2022:1247806
Stearoyl-CoA Desaturase-1 dependent lipid droplets accumulation in cancer-associated fibroblasts facilitates the progression of lung cancer.
Zhang Y, Gu Z, Wan J, Lou X, Liu S, Wang Y, Bian Y, Wang F, Li Z, Qin Z
International journal of biological sciences 2022;18(16):6114-6128
International journal of biological sciences 2022;18(16):6114-6128
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Liu C, Wang C, Yang F, Lu Y, Du P, Hu K, Yin X, Zhao P, Lu G
PloS one 2022;17(4):e0265049
PloS one 2022;17(4):e0265049
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
Drug design, development and therapy 2022;16:1713-1729
Drug design, development and therapy 2022;16:1713-1729
Effect of Tensile Frequency on the Osteogenic Differentiation of Periodontal Ligament Stem Cells.
Wang W, Wang M, Guo X, Zhao Y, Ahmed MMS, Qi H, Chen X
International journal of general medicine 2022;15:5957-5971
International journal of general medicine 2022;15:5957-5971
C-X-C-Chemokine-Receptor-Type-4 Inhibitor AMD3100 Attenuates Pulmonary Inflammation and Fibrosis in Silicotic Mice.
Sun Q, Tao X, Li B, Cao H, Chen H, Zou Y, Tao H, Mu M, Wang W, Xu K
Journal of inflammation research 2022;15:5827-5843
Journal of inflammation research 2022;15:5827-5843
STAMP2 Attenuates Cardiac Dysfunction and Insulin Resistance in Diabetic Cardiomyopathy via NMRAL1-Mediated NF-κB Inhibition in Type 2 Diabetic Rats.
Gao Z, Ti Y, Lu B, Song FQ, Zhang L, Hu BA, Xie JY, Zhang W, Han L, Zhong M
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3219-3229
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:3219-3229
Compared with High-intensity Interval Exercise, Moderate Intensity Constant Load Exercise is more effective in curbing the Growth and Metastasis of Lung Cancer.
Ge Z, Wu S, Qi Z, Ding S
Journal of Cancer 2022;13(5):1468-1479
Journal of Cancer 2022;13(5):1468-1479
CaM/CaMKII mediates activation and proliferation of hepatic stellate cells regulated by ASIC1a.
Liu H, Lu WL, Hong HQ, Li MJ, Ye MP, Rao QF, Kong JL, Luan SH, Huang Y, Hu QH, Wu FR
Frontiers in pharmacology 2022;13:996667
Frontiers in pharmacology 2022;13:996667
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
Huang Q, Xiao R, Lu J, Zhang Y, Xu L, Gao J, Sun J, Wang H
Frontiers in pharmacology 2022;13:973182
Frontiers in pharmacology 2022;13:973182
Phosphatidylethanolamine-binding protein 4 deficiency exacerbates carbon tetrachloride-induced liver fibrosis by regulating the NF-κB signaling pathway.
Luo Q, Ling Y, Li Y, Qu X, Shi Q, Zheng S, Li Y, Huang Y, Zhou X
Frontiers in pharmacology 2022;13:964829
Frontiers in pharmacology 2022;13:964829
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Zhan Z, Li A, Zhang W, Wu X, He J, Li Z, Li Y, Sun J, Zhang H
Frontiers in endocrinology 2022;13:914865
Frontiers in endocrinology 2022;13:914865
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Wang C, Sun Y
Frontiers in endocrinology 2022;13:823740
Frontiers in endocrinology 2022;13:823740
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Xiang J, Zhang H, Zhou X, Wang D, Chen R, Tan W, Liang L, Shi M, Zhang F, Xiao Y, Zhou Y, Wang Y, Guo B
Frontiers in pharmacology 2022;13:819787
Frontiers in pharmacology 2022;13:819787
Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.
Gu YH, Ren KW, Wang Y, Wang SH, Yu XH, Xu LW, Li HH, Bi HL
Frontiers in pharmacology 2022;13:1021361
Frontiers in pharmacology 2022;13:1021361
Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis.
Wang H, Jiang C, Yang Y, Li J, Wang Y, Wang C, Gao Y
PeerJ 2022;10:e13592
PeerJ 2022;10:e13592
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Dong Y, Lv D, Zhao Z, Xu Z, Hu Z, Tang B
Frontiers in bioengineering and biotechnology 2022;10:892015
Frontiers in bioengineering and biotechnology 2022;10:892015
miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα.
Ma H, Wang X, Liu X, Wang C, Gao X, Niu J
Frontiers in cell and developmental biology 2022;10:841248
Frontiers in cell and developmental biology 2022;10:841248
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
Niu Z, Wang L, Qin X, Ye Z, Xie B, Hu Y
Toxicology 2022 Sep;479:153310
Toxicology 2022 Sep;479:153310
Exosomal miR-7002-5p derived from highglucose-induced macrophages suppresses autophagy in tubular epithelial cells by targeting Atg9b.
Zhao J, Chen J, Zhu W, Qi XM, Wu YG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Sep;36(9):e22501
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Dong J, Zhang L, Ruan B, Lv Z, Wang H, Wang Y, Jiang Q, Cao W
Biomaterials 2022 Sep;288:121742
Biomaterials 2022 Sep;288:121742
LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.
Chen L, Su Y, Yin B, Li S, Cheng X, He Y, Jia C
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
The Journal of investigative dermatology 2022 Sep;142(9):2395-2405.e7
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Ma T, Cheng H, Li T, Chen Y, Cai T, Bai J, Wu Z, Xia X, Liang T, Du Y, Fu W
Bioorganic chemistry 2022 Sep;126:105899
Bioorganic chemistry 2022 Sep;126:105899
Nanosilicate-Reinforced Silk Fibroin Hydrogel for Endogenous Regeneration of Both Cartilage and Subchondral Bone.
Sheng R, Chen J, Wang H, Luo Y, Liu J, Chen Z, Mo Q, Chi J, Ling C, Tan X, Yao Q, Zhang W
Advanced healthcare materials 2022 Sep;11(17):e2200602
Advanced healthcare materials 2022 Sep;11(17):e2200602
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice.
Zhao K, Xu T, Mao Y, Wu X, Hua D, Sheng Y, Li P
Biology direct 2022 Sep 27;17(1):25
Biology direct 2022 Sep 27;17(1):25
PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling.
Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, Zhang R, Luan J, Zhu J, Gu X, Xiao T, Huang H, Chen S, Ning W, Yang G, Yang C, Zhou H
Science advances 2022 Sep 23;8(38):eabo0987
Science advances 2022 Sep 23;8(38):eabo0987
Grp94 Inhibitor HCP1 Inhibits Human Dermal Fibroblast Senescence.
Cui X, Hao X, Wen J, Zhang S, Zhao B, Miao J
Genes 2022 Sep 14;13(9)
Genes 2022 Sep 14;13(9)
EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy.
Gong Y, Dou Y, Wang L, Wang X, Zhao Z
Cellular signalling 2022 Oct;98:110407
Cellular signalling 2022 Oct;98:110407
A Combination Therapy Using Electrical Stimulation and Adaptive, Conductive Hydrogels Loaded with Self-Assembled Nanogels Incorporating Short Interfering RNA Promotes the Repair of Diabetic Chronic Wounds.
Lei H, Fan D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Oct;9(30):e2201425
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho.
Zhou W, Chen MM, Liu HL, Si ZL, Wu WH, Jiang H, Wang LX, Vaziri ND, An XF, Su K, Chen C, Tan NH, Zhang ZH
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
Acta pharmacologica Sinica 2022 Oct;43(10):2609-2623
Green Tea Polyphenols Prevent Early Vascular Aging Induced by High-Fat Diet via Promoting Autophagy in Young Adult Rats.
Xiao XT, He SQ, Wu NN, Lin XC, Zhao J, Tian C
Current medical science 2022 Oct;42(5):981-990
Current medical science 2022 Oct;42(5):981-990
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Guo Z, Geng M, Huang Y, Han G, Jing R, Lin C, Zhang X, Zhang M, Fan G, Wang F, Yin H
Cell death and differentiation 2022 Oct;29(10):1928-1940
Cell death and differentiation 2022 Oct;29(10):1928-1940
Epididymal white adipose tissue promotes angiotensin II-induced cardiac fibrosis in an exosome-dependent manner.
Su M, Li W, Yuan Y, Liu S, Liang C, Liu HE, Zhang R, Liu Y, Sun LI, Wei Y, Li C, Han X, Hao H, Zhao X, Luo Y, Yan S, Pan Z, Li Y
Translational research : the journal of laboratory and clinical medicine 2022 Oct;248:51-67
Translational research : the journal of laboratory and clinical medicine 2022 Oct;248:51-67
Curcumin analog JM-2 alleviates diabetic cardiomyopathy inflammation and remodeling by inhibiting the NF-κB pathway.
Wang M, Jin L, Zhang Q, Zhu W, He H, Lou S, Luo W, Han X, Liang G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113590
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113590
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
Zheng CM, Lu KC, Chen YJ, Li CY, Lee YH, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
FGFR2 Mutation p.Cys342Arg Enhances Mitochondrial Metabolism-Mediated Osteogenesis via FGF/FGFR-AMPK-Erk1/2 Axis in Crouzon Syndrome.
Wang Y, Liu Y, Chen H, Liu X, Zhang Y, Wang Y, Gu Y
Cells 2022 Oct 5;11(19)
Cells 2022 Oct 5;11(19)
HOCI Probe CPP Induces the Differentiation of Human Dermal Fibroblasts into Vascular Endothelial Cells through PHD2/HIF-1α/HEY1 Signaling Pathway.
Cui X, Wen J, Li N, Hao X, Zhang S, Zhao B, Wu X, Miao J
Cells 2022 Oct 4;11(19)
Cells 2022 Oct 4;11(19)
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Li M, Yang D, Yan H, Tang Z, Jiang D, Zhang J, Chi Z, Nie W, Zhen W, Yu W, Chen S, Wang Z, Yu Q, Zhang X, Yang F, Fan S, Lin X, Wang D
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Synergistic anti-inflammatory effect of gut microbiota and lithocholic acid on liver fibrosis.
Shao J, Ge T, Tang C, Wang G, Pang L, Chen Z
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1389-1401
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2022 Nov;71(10-11):1389-1401
Critical role of PAFR/YAP1 positive feedback loop in cardiac fibrosis.
Li TY, Su W, Li LL, Zhao XG, Yang N, Gai JX, Lv X, Zhang J, Huang MQ, Zhang Q, Ji WH, Song XY, Zhou YH, Li XL, Shan HL, Liang HH
Acta pharmacologica Sinica 2022 Nov;43(11):2862-2872
Acta pharmacologica Sinica 2022 Nov;43(11):2862-2872
Niobium promotes fracture healing in rats by regulating the PI3K-Akt signalling pathway: An in vivo and in vitro study.
Tan J, Li J, Cao B, Wu J, Luo D, Ran Z, Deng L, Li X, Jiang W, Xie K, Wang L, Hao Y
Journal of orthopaedic translation 2022 Nov;37:113-125
Journal of orthopaedic translation 2022 Nov;37:113-125
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Mai X, Shang J, Chen Q, Gu S, Hong Y, Zhou J, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
Pathological collagen targeting and penetrating liposomes for idiopathic pulmonary fibrosis therapy.
Yang MY, Lin YJ, Han MM, Bi YY, He XY, Xing L, Jeong JH, Zhou TJ, Jiang HL
Journal of controlled release : official journal of the Controlled Release Society 2022 Nov;351:623-637
Journal of controlled release : official journal of the Controlled Release Society 2022 Nov;351:623-637
Antifibrotic pyridine-containing monoterpene alkaloids from Caryopteris glutinosa.
Zhang X, Cao Y, Pan D, Yao X, Wang F, Zhang G, Luo Y
Phytochemistry 2022 Nov;203:113378
Phytochemistry 2022 Nov;203:113378
Blockade of the pentraxin 3/CD44 interaction attenuates lung injury-induced fibrosis.
Chi JY, Hsiao YW, Liang HY, Huang TH, Chen FW, Chen CY, Ko CY, Cheng CC, Wang JM
Clinical and translational medicine 2022 Nov;12(11):e1099
Clinical and translational medicine 2022 Nov;12(11):e1099
The Impact of Sleep Disturbance on Gut Microbiota, Atrial Substrate, and Atrial Fibrillation Inducibility in Mice: A Multi-Omics Analysis.
Zuo K, Fang C, Fu Y, Liu Z, Liu Y, Liu L, Wang Y, Wang H, Yin X, Liu X, Li J, Zhong J, Chen M, Yang X, Xu L
Metabolites 2022 Nov 20;12(11)
Metabolites 2022 Nov 20;12(11)
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
Alfonso García SL, Mira Uribe LM, Castaño López S, Parada-Sanchez MT, Arboleda-Toro D
Cells 2022 Nov 17;11(22)
Cells 2022 Nov 17;11(22)
Sophocarpine Alleviates Isoproterenol-Induced Kidney Injury by Suppressing Inflammation, Apoptosis, Oxidative Stress and Fibrosis.
Zhou W, Fu Y, Xu JS
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Molecules (Basel, Switzerland) 2022 Nov 15;27(22)
Dietary N(ε)-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
Wang ZQ, Sun Z
World journal of diabetes 2022 Nov 15;13(11):972-985
World journal of diabetes 2022 Nov 15;13(11):972-985
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway.
Li F, Wei R, Huang M, Chen J, Li P, Ma Y, Chen X
Food & function 2022 Nov 14;13(22):11896-11914
Food & function 2022 Nov 14;13(22):11896-11914
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
Yin X, Peng J, Gu L, Liu Y, Li X, Wu J, Xu B, Zhuge Y, Zhang F
Cell death & disease 2022 Nov 14;13(11):955
Cell death & disease 2022 Nov 14;13(11):955
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Yu Z, Xie X, Su X, Lv H, Song S, Liu C, You Y, Tian M, Zhu L, Wang L, Qi J, Zhu Q
Cellular signalling 2022 May;93:110304
Cellular signalling 2022 May;93:110304
Effects of thymoquinone against angiotensin II‑induced cardiac damage in apolipoprotein E‑deficient mice.
Zhang L, Zhang H, Ma J, Wang Y, Pei Z, Ding H
International journal of molecular medicine 2022 May;49(5)
International journal of molecular medicine 2022 May;49(5)
Interfering Hsa_circRNA_0060640 Suppresses TGF-β2-Induced Proliferation, Motility and EMT in Human Lens Epithelium Cells by Targeting miR-214-3p and Collagen Type I alpha2 Chain.
Guo M, Su F, Chen Y, Su B
Current eye research 2022 May;47(5):735-746
Current eye research 2022 May;47(5):735-746
Cryo-injury procedure-induced cardiac regeneration shows unique gene expression profiles in the newt Pleurodeles waltl.
Uemasu H, Ikuta H, Igawa T, Suzuki M, Kyakuno M, Iwata Y, Tazawa I, Ogino H, Satoh Y, Takeuchi T, Namba N, Hayashi T
Developmental dynamics : an official publication of the American Association of Anatomists 2022 May;251(5):864-876
Developmental dynamics : an official publication of the American Association of Anatomists 2022 May;251(5):864-876
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease.
Zhan Y, Chen J, Wu J, Gu Y, Huang Q, Deng Z, Chen S, Wu X, Lv Y, Zeng Z, Xie J
Respiratory research 2022 May 12;23(1):120
Respiratory research 2022 May 12;23(1):120
MicroRNA-24-3p alleviates cardiac fibrosis by suppressing cardiac fibroblasts mitophagy via downregulating PHB2.
Zhang Y, Wang Z, Lan D, Zhao J, Wang L, Shao X, Wang D, Wu K, Sun M, Huang X, Yan M, Liang H, Rong X, Diao H, Guo J
Pharmacological research 2022 Mar;177:106124
Pharmacological research 2022 Mar;177:106124
Improved epicardial cardiac fibroblast generation from iPSCs.
Whitehead AJ, Hocker JD, Ren B, Engler AJ
Journal of molecular and cellular cardiology 2022 Mar;164:58-68
Journal of molecular and cellular cardiology 2022 Mar;164:58-68
Rab31 promotes activation of hepatic stellate cells by accelerating TGF-β receptor II complex endocytosis.
Qiu C, Liu Y, Huang S, Ning B, He S, Zhong L
The international journal of biochemistry & cell biology 2022 Mar;144:106170
The international journal of biochemistry & cell biology 2022 Mar;144:106170
Injectable recombinant human collagen-derived material with high cell adhesion activity limits adverse remodelling and improves pelvic floor function in pelvic floor dysfunction rats.
Li H, You S, Yang X, Liu S, Hu L
Biomaterials advances 2022 Mar;134:112715
Biomaterials advances 2022 Mar;134:112715
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
Feng Y, Bao Y, Ding J, Li H, Liu W, Wang X, Guan H, Chen Z
Bioengineered 2022 Mar;13(3):5779-5791
Bioengineered 2022 Mar;13(3):5779-5791
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Shi J, Sun J, Liu L, Shan T, Meng H, Yang T, Wang S, Wei T, Chen B, Ma Y, Wang Q, Wang H, Liu J, Wang L
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling.
Liu P, Li Y, Li M, Zhou H, Zhang H, Zhang Y, Xu J, Xu Y, Zhang J, Xia B, Cheng H, Ke Y, Zhang X
iScience 2022 Mar 18;25(3):103867
iScience 2022 Mar 18;25(3):103867
Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox.
Wang ZX, Luo ZW, Li FX, Cao J, Rao SS, Liu YW, Wang YY, Zhu GQ, Gong JS, Zou JT, Wang Q, Tan YJ, Zhang Y, Hu Y, Li YY, Yin H, Wang XK, He ZH, Ren L, Liu ZZ, Hu XK, Yuan LQ, Xu R, Chen CY, Xie H
Nature communications 2022 Mar 18;13(1):1453
Nature communications 2022 Mar 18;13(1):1453
Daidzein suppresses TGF-β1-induced cardiac fibroblast activation via the TGF-β1/SMAD2/3 signaling pathway.
Shu J, Hu L, Wu Y, Chen L, Huang K, Wang Z, Liang M
European journal of pharmacology 2022 Mar 15;919:174805
European journal of pharmacology 2022 Mar 15;919:174805
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Gu W, Wang L, Deng G, Gu X, Tang Z, Li S, Jin W, Yang J, Guo X, Li Q
Toxicology letters 2022 Mar 1;357:11-19
Toxicology letters 2022 Mar 1;357:11-19
Adiponectin Alleviates Intestinal Fibrosis by Enhancing AMP-Activated Protein Kinase Phosphorylation.
Xie M, Xiong Z, Yin S, Xiong J, Li X, Jin L, Zhang F, Chen H, Lan P, Lian L
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
Digestive diseases and sciences 2022 Jun;67(6):2232-2243
Pyrroloquinoline quinone ameliorates diabetic cardiomyopathy by inhibiting the pyroptosis signaling pathway in C57BL/6 mice and AC16 cells.
Qu XF, Zhai BZ, Hu WL, Lou MH, Chen YH, Liu YF, Chen JG, Mei S, You ZQ, Liu Z, Zhang LJ, Zhang YH, Wang Y
European journal of nutrition 2022 Jun;61(4):1823-1836
European journal of nutrition 2022 Jun;61(4):1823-1836
Citri Reticulatae Pericarpium alleviates postmyocardial infarction heart failure by upregulating PPARγ expression.
Chen M, Zhu H, Zhu Q, Wu X, Zhou Y, Gao R, Shi M, Zhang T, Yin T, Zhang H, Shang H, Li X
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):661-673
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):661-673
Atorvastatin reduces IOP in ocular hypertension in vivo and suppresses ECM in trabecular meshwork perhaps via FGD4.
Song XY, Chen YY, Liu WT, Cong L, Zhang JL, Zhang Y, Zhang YY
International journal of molecular medicine 2022 Jun;49(6)
International journal of molecular medicine 2022 Jun;49(6)
Protection of CAPE-pNO(2) Against Chronic Myocardial Ischemia by the TGF-Β1/Galectin-3 Pathway In Vivo and In Vitro.
Wan Q, Zhang L, Zhou Q, Han Y, Li Z, Li B
Inflammation 2022 Jun;45(3):1039-1058
Inflammation 2022 Jun;45(3):1039-1058
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
Jie L, Hong RT, Zhang YJ, Sha LL, Chen W, Ren XF
Current medical science 2022 Jun;42(3):498-504
Current medical science 2022 Jun;42(3):498-504
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Wang S, Yan H, Fang B, Gu C, Guo J, Qiu P, Song N, Xu W, Zhang J, Lin X, Fang X
Biomaterials 2022 Jun;285:121519
Biomaterials 2022 Jun;285:121519
Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells.
Qu X, Zhai B, Liu Y, Chen Y, Xie Z, Wang Q, Wu Y, Liu Z, Chen J, Mei S, Wu J, You Z, Yu Y, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112998
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112998
Histamine Deficiency Promotes Myofibroblasts Transformation from HDC-Expressing CD11b(+) Myeloid Cells in Injured Hearts Post Myocardial Infarction.
Zhu B, Zhu X, Wang X, Wu J, Ding S, Zhang W, Zou Y, Ge J, Yang X
Journal of cardiovascular translational research 2022 Jun;15(3):621-634
Journal of cardiovascular translational research 2022 Jun;15(3):621-634
Human amniotic fluid mesenchymal stem cells attenuate pancreatic cancer cell proliferation and tumor growth in an orthotopic xenograft mouse model.
Chen YC, Lan YW, Huang SM, Yen CC, Chen W, Wu WJ, Staniczek T, Chong KY, Chen CM
Stem cell research & therapy 2022 Jun 3;13(1):235
Stem cell research & therapy 2022 Jun 3;13(1):235
Long noncoding RNA GAS5 attenuates cigarette smoke-induced airway remodeling by regulating miR-217-5p/PTEN axis.
Du Y, Ding Y, Shi T, He W, Feng J, Mei Z, Chen X, Feng X, Zhang X, Jie Z
Acta biochimica et biophysica Sinica 2022 Jun 25;54(7):931-939
Acta biochimica et biophysica Sinica 2022 Jun 25;54(7):931-939
Beta-hydroxybutyrate dampens adipose progenitors' profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms.
Lecoutre S, Merabtene F, El Hachem EJ, Gamblin C, Rouault C, Sokolovska N, Soula H, Lai WS, Blackshear PJ, Clément K, Dugail I
Molecular metabolism 2022 Jul;61:101512
Molecular metabolism 2022 Jul;61:101512
Integrated multicomponent analysis based on UHPLC-Q-Exactive Orbitrap-MS and network pharmacology to elucidate the potential mechanism of Baoyuan decoction against idiopathic pulmonary fibrosis.
Zhang B, Gao D, Xu G, Zhu W, Liu J, Sun R, Wang L, Zhang C, Ding Q, Shi Y
Phytochemical analysis : PCA 2022 Jul;33(5):678-695
Phytochemical analysis : PCA 2022 Jul;33(5):678-695
KGF-2 Regulates STAP-2-Mediated Signal Transducer and Activator of Transcription 3 Signaling and Reduces Skin Scar Formation.
Zhou Q, Gong J, Bi J, Yang X, Zhang L, Lu C, Li L, Chen M, Cai J, Yang R, Li X, Li Z, Wang X
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
The Journal of investigative dermatology 2022 Jul;142(7):2003-2013.e5
Postnatal Deletion of Bmal1 in Cardiomyocyte Promotes Pressure Overload Induced Cardiac Remodeling in Mice.
Liang Q, Xu H, Liu M, Qian L, Yan J, Yang G, Chen L
Journal of the American Heart Association 2022 Jul 5;11(13):e025021
Journal of the American Heart Association 2022 Jul 5;11(13):e025021
Bone marrow mesenchymal stem cells inhibit hepatic fibrosis via the AABR07028795.2/rno-miR-667-5p axis.
Feng Y, Li Y, Xu M, Meng H, Dai C, Yao Z, Lin N
Stem cell research & therapy 2022 Jul 28;13(1):375
Stem cell research & therapy 2022 Jul 28;13(1):375
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1.
Ma R, Zhang D, Song Y, Kong J, Mu C, Shen P, Gui W
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):961-973
TGFβ1-transfected tendon stem cells promote tendon fibrosis.
Yu HB, Xiong J, Zhang HZ, Chen Q, Xie XY
Journal of orthopaedic surgery and research 2022 Jul 21;17(1):358
Journal of orthopaedic surgery and research 2022 Jul 21;17(1):358
Revealing the mechanism of Jiegeng decoction attenuates bleomycin-induced pulmonary fibrosis via PI3K/Akt signaling pathway based on lipidomics and transcriptomics.
Xu Y, Wang X, Han D, Wang J, Luo Z, Jin T, Shi C, Zhou X, Lin L, Shan J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154207
ANGPTL8 is a negative regulator in pathological cardiac hypertrophy.
Hu L, Wei J, Zhang Y, Wang Z, Tang J, Tang J, Gao Y, Zhang X, Li Y, Liu Y, Ma S, Guo X, Zhang Q
Cell death & disease 2022 Jul 18;13(7):621
Cell death & disease 2022 Jul 18;13(7):621
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Morphological changes of macrophages and their potential contribution to tendon healing.
Yang QQ, Zhang L, Zhou YL, Tang JB
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
Colloids and surfaces. B, Biointerfaces 2022 Jan;209(Pt 1):112145
VX-765 ameliorates renal injury and fibrosis in diabetes by regulating caspase-1-mediated pyroptosis and inflammation.
Wen S, Deng F, Li L, Xu L, Li X, Fan Q
Journal of diabetes investigation 2022 Jan;13(1):22-33
Journal of diabetes investigation 2022 Jan;13(1):22-33
Long-term explant culture: an improved method for consistently harvesting homogeneous populations of keloid fibroblasts.
Li J, Zou Y, Wang S, Guo S, Huang Z, Huo R
Bioengineered 2022 Jan;13(1):1565-1574
Bioengineered 2022 Jan;13(1):1565-1574
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
Ning J, Du H, Zhang Y, Liu Q, Jiang T, Pang Y, Tian X, Yan L, Niu Y, Zhang R
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion.
Airik M, McCourt B, Ozturk TT, Huynh AB, Zhang X, Tometich JT, Topaloglu R, Ozen H, Orhan D, Nejak-Bowen K, Monga SP, Hand TW, Ozaltin F, Airik R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Feb;36(2):e22157
Protein tyrosine phosphatase 1B regulates fibroblasts proliferation, motility and extracellular matrix synthesis via the MAPK/ERK signalling pathway in keloid.
Qian L, Wang Q, Wei C, Wang L, Yang Y, Deng X, Liu J, Qi F
Experimental dermatology 2022 Feb;31(2):202-213
Experimental dermatology 2022 Feb;31(2):202-213
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Xie L, Wang T, Lin S, Lu Z, Wang Y, Shen Z, Cheng Y, Shen A, Peng J, Chu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Berberine ameliorates erectile dysfunction in rats with streptozotocin-induced diabetes mellitus through the attenuation of apoptosis by inhibiting the SPHK1/S1P/S1PR2 and MAPK pathways.
Liu K, Sun T, Luan Y, Chen Y, Song J, Ling L, Yuan P, Li R, Cui K, Ruan Y, Lan R, Wang T, Wang S, Liu J, Rao K
Andrology 2022 Feb;10(2):404-418
Andrology 2022 Feb;10(2):404-418
A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer.
Yang C, Zhang H, Chen M, Wang S, Qian R, Zhang L, Huang X, Wang J, Liu Z, Qin W, Wang C, Hang H, Wang H
eLife 2022 Feb 22;11
eLife 2022 Feb 22;11
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Tao H, Zhao H, Ge D, Liao J, Shao L, Mo A, Hu L, Xu K, Wu J, Mu M, Li B, Tao X, Wang J
Toxicology letters 2022 Feb 1;355:150-159
Toxicology letters 2022 Feb 1;355:150-159
Qingda granule prevents obesity-induced hypertension and cardiac dysfunction by inhibiting adverse Akt signaling activation.
Gao Q, Ma E, Chen J, Zhao Q, He J, Peng J, Zhu W, Ren DN, Wo D
Heliyon 2022 Dec;8(12):e12099
Heliyon 2022 Dec;8(12):e12099
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy.
Lv S, Zhang W, Yuan P, Lu C, Dong J, Zhang J
Pharmaceutical biology 2022 Dec;60(1):722-728
Pharmaceutical biology 2022 Dec;60(1):722-728
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway.
Wang H, Jiang Q, Zhang L
Pharmaceutical biology 2022 Dec;60(1):1407-1416
Pharmaceutical biology 2022 Dec;60(1):1407-1416
Cellular communication network factor 1 interlinks autophagy and ERK signaling to promote osteogenesis of periodontal ligament stem cells.
Li Z, Wu Z, Xi X, Zhao F, Liu H, Liu D
Journal of periodontal research 2022 Dec;57(6):1169-1182
Journal of periodontal research 2022 Dec;57(6):1169-1182
CircHOMER1 aggravates oxidative stress, inflammation and extracellular matrix deposition in high glucose-induced human mesangial cells.
Shu S, Xu Z, Lu H, Li Z, Zhang Y
Nephrology (Carlton, Vic.) 2022 Dec;27(12):983-993
Nephrology (Carlton, Vic.) 2022 Dec;27(12):983-993
An improved explants culture method: Sustainable isolation of keloid fibroblasts with primary characteristics.
He Y, Zhang S, Bao W, Xue Y, Yin B, Cheng X, Zhang Z, Jia C
Journal of cosmetic dermatology 2022 Dec;21(12):7131-7139
Journal of cosmetic dermatology 2022 Dec;21(12):7131-7139
PVA/pectin composite hydrogels inducing osteogenesis for bone regeneration.
Hu Z, Cheng J, Xu S, Cheng X, Zhao J, Kenny Low ZW, Chee PL, Lu Z, Zheng L, Kai D
Materials today. Bio 2022 Dec;16:100431
Materials today. Bio 2022 Dec;16:100431
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
Bioprinted living tissue constructs with layer-specific, growth factor-loaded microspheres for improved enthesis healing of a rotator cuff.
Bai L, Han Q, Meng Z, Chen B, Qu X, Xu M, Su Y, Qiu Z, Xue Y, He J, Zhang J, Yin Z
Acta biomaterialia 2022 Dec;154:275-289
Acta biomaterialia 2022 Dec;154:275-289
Freeze-casting osteochondral scaffolds: The presence of a nutrient-permeable film between the bone and cartilage defect reduces cartilage regeneration.
Chen J, Li Y, Liu S, Du Y, Zhang S, Wang J
Acta biomaterialia 2022 Dec;154:168-179
Acta biomaterialia 2022 Dec;154:168-179
IL-8 exacerbates CCl(4)-induced liver fibrosis in human IL-8-expressing mice via the PI3K/Akt/HIF-1α pathway.
Ma Y, Bao Y, Wu L, Ke Y, Tan L, Ren H, Song J, Zhang Q, Jin Y
Molecular immunology 2022 Dec;152:111-122
Molecular immunology 2022 Dec;152:111-122
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Lian N, Jin H, Zhu W, Zhang C, Qi Y, Jiang M, Mao J, Lu X, Zhao F, Xi B, Qi X, Li Y
Acta histochemica 2022 Dec;124(8):151961
Acta histochemica 2022 Dec;124(8):151961
β3 adrenoceptor agonist mirabegron protects against right ventricular remodeling and drives Drp1 inhibition.
Zhao L, Luo H, Li T, Zhao X, Liu Y
Cardiovascular diagnosis and therapy 2022 Dec;12(6):815-827
Cardiovascular diagnosis and therapy 2022 Dec;12(6):815-827
Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice.
Zhang L, Zhang H, Gu J, Xu W, Yuan N, Sun J, Li H
International immunopharmacology 2022 Dec;113(Pt B):109433
International immunopharmacology 2022 Dec;113(Pt B):109433
Astrocyte-derived sEVs alleviate fibrosis and promote functional recovery after spinal cord injury in rats.
Lu Y, Chen C, Wang H, Du R, Ji J, Xu T, Yang C, Chen X
International immunopharmacology 2022 Dec;113(Pt A):109322
International immunopharmacology 2022 Dec;113(Pt A):109322
Hydroxyapatite-Tethered Peptide Hydrogel Promotes Osteogenesis.
Yu H, Song J, Zhang X, Jiang K, Fan H, Li Y, Zhao Y, Liu S, Hao D, Li G
Gels (Basel, Switzerland) 2022 Dec 8;8(12)
Gels (Basel, Switzerland) 2022 Dec 8;8(12)
The m(6)A methyltransferase Mettl3 deficiency attenuates hepatic stellate cell activation and liver fibrosis.
Li Y, Kang X, Zhou Z, Pan L, Chen H, Liang X, Chu J, Dong S, Liu C, Yu S, Tu D, Zhang Y, Ge M, Chen W, Xu Y, Zhang Q
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3714-3728
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Dec 7;30(12):3714-3728
Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3.
Bai Y, Liu J, Jiang X, Li X, Zhang B, Luo X
Cells 2022 Dec 3;11(23)
Cells 2022 Dec 3;11(23)
TIPARP is involved in the regulation of intraocular pressure.
Zhang Y, Song M, Bi Y, Lei Y, Sun X, Chen Y
Communications biology 2022 Dec 19;5(1):1386
Communications biology 2022 Dec 19;5(1):1386
Non-cell-autonomous activation of hedgehog signaling contributes to disease progression in a mouse model of renal cystic ciliopathy.
Hsieh CL, Jerman SJ, Sun Z
Human molecular genetics 2022 Dec 16;31(24):4228-4240
Human molecular genetics 2022 Dec 16;31(24):4228-4240
ER-phagy Is Involved in the Degradation of Collagen I by IL-1β in Human Amnion in Parturition.
Mi YB, Liu XH, Wang WS, Wang LY, Ling LJ, Sun K, Ying H
Journal of immunology (Baltimore, Md. : 1950) 2022 Dec 15;209(12):2322-2329
Journal of immunology (Baltimore, Md. : 1950) 2022 Dec 15;209(12):2322-2329
Nanosilica-Anchored Polycaprolactone/Chitosan Nanofibrous Bioscaffold to Boost Osteogenesis for Bone Tissue Engineering.
Ge S, Zhu X, Zhang C, Jia D, Shang W, Ding C, Yang J, Feng Y
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Molecules (Basel, Switzerland) 2022 Dec 13;27(24)
Fluid Shear Stress Regulates Osteogenic Differentiation via AnnexinA6-Mediated Autophagy in MC3T3-E1 Cells.
Pei T, Su G, Yang J, Gao W, Yang X, Zhang Y, Ren J, Shen Y, Liu X
International journal of molecular sciences 2022 Dec 11;23(24)
International journal of molecular sciences 2022 Dec 11;23(24)
Extracellular matrix modulating enzyme functionalized biomimetic Au nanoplatform-mediated enhanced tumor penetration and synergistic antitumor therapy for pancreatic cancer.
Yang XY, Zhang JG, Zhou QM, Yu JN, Lu YF, Wang XJ, Zhou JP, Ding XF, Du YZ, Yu RS
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Journal of nanobiotechnology 2022 Dec 10;20(1):524
Piezo1 act as a potential oncogene in pancreatic cancer progression.
Zhu Z, Li W, Gong M, Wang L, Yue Y, Qian W, Zhou C, Duan W, Han L, Li L, Wu Z, Ma Q, Lin M, Wang S, Wang Z
Life sciences 2022 Dec 1;310:121035
Life sciences 2022 Dec 1;310:121035
Celecoxib activates autophagy by inhibiting the mTOR signaling pathway and prevents apoptosis in nucleus pulposus cells.
Chen W, Yasen M, Wang H, Zhuang C, Wang Z, Lu S, Jiang L, Lin H
BMC pharmacology & toxicology 2022 Dec 1;23(1):90
BMC pharmacology & toxicology 2022 Dec 1;23(1):90
Exercise-derived peptide protects against pathological cardiac remodeling.
Yin A, Yuan R, Xiao Q, Zhang W, Xu K, Yang X, Yang W, Xu L, Wang X, Zhuang F, Li Y, Cai Z, Sun Z, Zhou B, He B, Shen L
EBioMedicine 2022 Aug;82:104164
EBioMedicine 2022 Aug;82:104164
Thin film nanoarchitectonics of layer-by-layer assembly with reduced graphene oxide on intraocular lens for photothermal therapy of posterior capsular opacification.
Zhang C, Guo Q, Tong Z, Chen S, Mao Z, Yu Y
Journal of colloid and interface science 2022 Aug;619:348-358
Journal of colloid and interface science 2022 Aug;619:348-358
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Feng XW, Cheng QL, Fang L, Liu WY, Liu LW, Sun CQ, Lu ZH, Li GM, Gu RZ
Journal of food biochemistry 2022 Aug;46(8):e14162
Journal of food biochemistry 2022 Aug;46(8):e14162
Hypoxia facilitates proliferation of smooth muscle cells derived from pluripotent stem cells for vascular tissue engineering.
Fang L, Mei J, Yao B, Liu J, Liu P, Wang X, Zhou J, Lin Z
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
Journal of tissue engineering and regenerative medicine 2022 Aug;16(8):744-756
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
AGEs-RAGE axis mediates myocardial fibrosis via activation of cardiac fibroblasts induced by autophagy in heart failure.
Liang B, Zhou Z, Yang Z, Liu J, Zhang L, He J, Li H, Huang Y, Yang Q, Xian S, Wang L
Experimental physiology 2022 Aug;107(8):879-891
Experimental physiology 2022 Aug;107(8):879-891
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
An L, Zhang M, Lin Y, Jiang T, Xu K, Xiao S, Cai L, Kwan HY, Liu Z, Su T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Lidocaine Inhibited Tendon Cell Proliferation and Extracellular Matrix Production by Down Regulation of Cyclin A, CDK2, Type I and Type III Collagen Expression.
Chen YC, Chang HN, Pang JS, Lin LP, Chen JM, Yu TY, Tsai WC
International journal of molecular sciences 2022 Aug 7;23(15)
International journal of molecular sciences 2022 Aug 7;23(15)
The compound losartan cream inhibits scar formation via TGF-β/Smad pathway.
Zhao WY, Zhang LY, Wang ZC, Fang QQ, Wang XF, Du YZ, Shi BH, Lou D, Xuan GD, Tan WQ
Scientific reports 2022 Aug 22;12(1):14327
Scientific reports 2022 Aug 22;12(1):14327
Maresin1 Suppresses High-Glucose-Induced Ferroptosis in Osteoblasts via NRF2 Activation in Type 2 Diabetic Osteoporosis.
Zhang Z, Ji C, Wang YN, Liu S, Wang M, Xu X, Zhang D
Cells 2022 Aug 17;11(16)
Cells 2022 Aug 17;11(16)
Targeted inhibition of TGF-β type I receptor by AZ12601011 protects against kidney fibrosis.
Suo XG, Wang F, Xu CH, He XY, Wang JN, Zhang Y, Ni WJ, Lu H, Ji ML, He Y, Xie SS, Yang YR, Wen JG, Jin J, Gong Q, Li J, Liu MM, Meng XM
European journal of pharmacology 2022 Aug 15;929:175116
European journal of pharmacology 2022 Aug 15;929:175116
Semaphorin 3A attenuates the hypoxia suppression of osteogenesis in periodontal ligament stem cells.
Chang X, Zhou F, Bu L, Wang N, Deng J, Wang S
Journal of periodontal research 2022 Apr;57(2):425-433
Journal of periodontal research 2022 Apr;57(2):425-433
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts.
Dubey S, Dubey PK, Umeshappa CS, Ghebre YT, Krishnamurthy P
Journal of cellular physiology 2022 Apr;237(4):2169-2182
Journal of cellular physiology 2022 Apr;237(4):2169-2182
Suppression of LMCD1 ameliorates renal fibrosis by blocking the activation of ERK pathway.
Yu R, Tian M, He P, Chen J, Zhao Z, Zhang Y, Zhang B
Biochimica et biophysica acta. Molecular cell research 2022 Apr;1869(4):119200
Biochimica et biophysica acta. Molecular cell research 2022 Apr;1869(4):119200
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Wei A, Gao Q, Chen F, Zhu X, Chen X, Zhang L, Su X, Dai J, Shi Y, Cao W
British journal of pharmacology 2022 Apr;179(7):1304-1318
British journal of pharmacology 2022 Apr;179(7):1304-1318
N-acetylcysteine promotes cyclic mechanical stress-induced osteogenic differentiation of periodontal ligament stem cells by down-regulating Nrf2 expression.
Xi X, Li ZX, Zhao Y, Liu H, Chen S, Liu DX
Journal of dental sciences 2022 Apr;17(2):750-762
Journal of dental sciences 2022 Apr;17(2):750-762
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Liu Z, Xu B, Ding Y, Ding X, Yang Z
Bioengineered 2022 Apr;13(4):9357-9368
Bioengineered 2022 Apr;13(4):9357-9368
MCC950 ameliorates ventricular arrhythmia vulnerability induced by heart failure.
Jiang X, Yang F, Ou D, Huang L, Li H, Lang M
Bioengineered 2022 Apr;13(4):8593-8604
Bioengineered 2022 Apr;13(4):8593-8604
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression.
Li J, Li Z, Wang S, Bi J, Huo R
Bioengineered 2022 Apr;13(4):8515-8525
Bioengineered 2022 Apr;13(4):8515-8525
PEDF is an antifibrosis factor that inhibits the activation of fibroblasts in a bleomycin-induced pulmonary fibrosis rat model.
Qin X, Jia C, Liang J, Chen J, Liu X, Chao Z, Qin H, Yuan Y, Liu Z, Zhang Z, Dong H, Zhang H
Respiratory research 2022 Apr 22;23(1):100
Respiratory research 2022 Apr 22;23(1):100
Exosomes derived from hypoxia preconditioned mesenchymal stem cells laden in a silk hydrogel promote cartilage regeneration via the miR-205-5p/PTEN/AKT pathway.
Shen K, Duan A, Cheng J, Yuan T, Zhou J, Song H, Chen Z, Wan B, Liu J, Zhang X, Zhang Y, Xie R, Liu F, Fan W, Zuo Q
Acta biomaterialia 2022 Apr 15;143:173-188
Acta biomaterialia 2022 Apr 15;143:173-188
Nrf2 Activation Is Involved in Cyclic Mechanical Stress-Stimulated Osteogenic Differentiation in Periodontal Ligament Stem Cells via PI3K/Akt Signaling and HO1-SOD2 Interaction.
Xi X, Li Z, Liu H, Chen S, Liu D
Frontiers in cell and developmental biology 2021;9:816000
Frontiers in cell and developmental biology 2021;9:816000
Epigenetic Repression of Chloride Channel Accessory 2 Transcription in Cardiac Fibroblast: Implication in Cardiac Fibrosis.
Shao T, Xue Y, Fang M
Frontiers in cell and developmental biology 2021;9:771466
Frontiers in cell and developmental biology 2021;9:771466
Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H
Frontiers in cell and developmental biology 2021;9:719351
Frontiers in cell and developmental biology 2021;9:719351
Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication.
Pan C, Fang Q, Liu P, Ma D, Cao S, Zhang L, Chen Q, Hu T, Wang J
Frontiers in cell and developmental biology 2021;9:708513
Frontiers in cell and developmental biology 2021;9:708513
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694
Frontiers in medicine 2021;8:807694
Isoproterenol-Induced Cardiomyopathy Recovery Intervention: Amlexanox and Forskolin Enhances the Resolution of Catecholamine Stress-Induced Maladaptive Myocardial Remodeling.
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adu-Amankwaah J, Shang W, Li K, Deng QM, Mprah R, Ndzie Noah ML, Sun H
Frontiers in cardiovascular medicine 2021;8:719805
Frontiers in cardiovascular medicine 2021;8:719805
Estrogen Protects Vasomotor Functions in Rats During Catecholamine Stress.
Zhang L, Li C, Yang L, Adzika GK, Machuki JO, Shi M, Sun Q, Sun H
Frontiers in cardiovascular medicine 2021;8:679240
Frontiers in cardiovascular medicine 2021;8:679240
Early Passive Leg Movement Prevents Against the Development of Heart Failure With Preserved Ejection Fraction in Rats.
Liu J, Ji XX, Fu Y, Zhang WC, Ji HF, Liu JW, Cheng XS, Dong YF
Frontiers in cardiovascular medicine 2021;8:655009
Frontiers in cardiovascular medicine 2021;8:655009
In Vitro Methods to Evaluate the Effects of Mesenchymal Stem Cells on TGF-β1-Induced Pulmonary Fibrosis.
Lan YW, Chen CM, Chong KY
Methods in molecular biology (Clifton, N.J.) 2021;2269:83-92
Methods in molecular biology (Clifton, N.J.) 2021;2269:83-92
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Zhou Y, Yin T, Shi M, Chen M, Wu X, Wang K, Cheang I, Li Y, Shang H, Zhang H, Li X
PPAR research 2021;2021:9947656
PPAR research 2021;2021:9947656
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Deficiency of IKKα in Macrophages Mitigates Fibrosis Progression in the Kidney after Renal Ischemia-Reperfusion Injury.
Zhang F, Fan L, Zhang H, Huang WJ, Sun D, Pan BB, Wan X, Cao CC
Journal of immunology research 2021;2021:5521051
Journal of immunology research 2021;2021:5521051
CircRNA FAT1 Regulates Osteoblastic Differentiation of Periodontal Ligament Stem Cells via miR-4781-3p/SMAD5 Pathway.
Ye Y, Ke Y, Liu L, Xiao T, Yu J
Stem cells international 2021;2021:5177488
Stem cells international 2021;2021:5177488
NEDD4L-induced β-catenin ubiquitination suppresses the formation and progression of interstitial pulmonary fibrosis via inhibiting the CTHRC1/HIF-1α axis.
Chen L, Yang Y, Yan H, Peng X, Zou J
International journal of biological sciences 2021;17(13):3320-3330
International journal of biological sciences 2021;17(13):3320-3330
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Pressing Intervention Promotes the Skeletal Muscle Repair of Traumatic Myofascial Trigger Points in Rats.
Jiang Q, Feng X, Liu D, Li T, Kuang X, Liu X, Li W, Li J
Journal of pain research 2021;14:3267-3278
Journal of pain research 2021;14:3267-3278
Substance P-induced RAD16-I scaffold mediated hUCMSCs stereo-culture triggers production of mineralized nodules and collagen-like fibers by promoting osteogenic genes expression.
Li Y, Zhang S, Li W, Zheng X, Xue Y, Hu K, Zhou H
American journal of translational research 2021;13(4):1990-2005
American journal of translational research 2021;13(4):1990-2005
Deletion of p16 accelerates fracture healing in geriatric mice.
Ding Q, Liu H, Liu L, Ma C, Qin H, Wei Y, Ren Y
American journal of translational research 2021;13(10):11107-11125
American journal of translational research 2021;13(10):11107-11125
Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence.
Li Q, Deng Y, Liu L, Zhang C, Cai Y, Zhang T, Han M, Xu G
Frontiers in immunology 2021;12:823935
Frontiers in immunology 2021;12:823935
Resolvin D1 attenuates CCl4 Induced Liver Fibrosis by Inhibiting Autophagy-Mediated HSC activation via AKT/mTOR Pathway.
Li J, Deng X, Wang S, Jiang Q, Xu K
Frontiers in pharmacology 2021;12:792414
Frontiers in pharmacology 2021;12:792414
Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway.
Zhang X, Wang L, Guo R, Xiao J, Liu X, Dong M, Luan X, Ji X, Lu H
Frontiers in pharmacology 2021;12:753881
Frontiers in pharmacology 2021;12:753881
Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney.
Rong Q, Han B, Li Y, Yin H, Li J, Hou Y
Frontiers in pharmacology 2021;12:729384
Frontiers in pharmacology 2021;12:729384
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
You S, Xu J, Wu B, Wu S, Zhang Y, Sun Y, Zhang N
Frontiers in genetics 2021;12:698570
Frontiers in genetics 2021;12:698570
LncRNA Nuclear-Enriched Abundant Transcript 1 Regulates Atrial Fibrosis via the miR-320/NPAS2 Axis in Atrial Fibrillation.
Dai H, Zhao N, Liu H, Zheng Y, Zhao L
Frontiers in pharmacology 2021;12:647124
Frontiers in pharmacology 2021;12:647124
Activation of the Cholinergic Anti-inflammatory Pathway Attenuated Angiotension II-Dependent Hypertension and Renal Injury.
Wu SJ, Shi ZW, Wang X, Ren FF, Xie ZY, Lei L, Chen P
Frontiers in pharmacology 2021;12:593682
Frontiers in pharmacology 2021;12:593682
Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries.
Tsai WC, Yu TY, Chang GJ, Chang HN, Lin LP, Lin MS, Pang JS
The American journal of sports medicine 2021 Sep;49(11):3102-3112
The American journal of sports medicine 2021 Sep;49(11):3102-3112
Identifying miRNA modules associated with progression of keloids through weighted gene co-expression network analysis and experimental validation in vitro.
Lv W, Ren Y, Wu M, Luo X, Yu J, Zhang Q, Wu Y
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Burns : journal of the International Society for Burn Injuries 2021 Sep;47(6):1359-1372
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
Zhao W, Zhang X, Hou M, Zhang Y, Tang Y, Li L, Dong S, Liu L, Zhao D, Li W, Nan Y
Histology and histopathology 2021 Sep;36(9):967-979
Histology and histopathology 2021 Sep;36(9):967-979
Exercise training ameliorates early diabetic kidney injury by regulating the H(2) S/SIRT1/p53 pathway.
Yang L, Li DX, Cao BQ, Liu SJ, Xu DH, Zhu XY, Liu YJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Sep;35(9):e21823
IGF-1-Expressing Placenta-Derived Mesenchymal Stem Cells Promote Scalding Wound Healing.
Cheng S, Lv R, Xu J, Hirman AR, Du L
The Journal of surgical research 2021 Sep;265:100-113
The Journal of surgical research 2021 Sep;265:100-113
Hydrogen gas inhalation ameliorates cardiac remodelling and fibrosis by regulating NLRP3 inflammasome in myocardial infarction rats.
Nie C, Zou R, Pan S, A R, Gao Y, Yang H, Bai J, Xi S, Wang X, Hong X, Yang W
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
Journal of cellular and molecular medicine 2021 Sep;25(18):8997-9010
The different functions of short and long thymic stromal lymphopoietin isoforms in autophagy-mediated asthmatic airway inflammation and remodeling.
Zhao J, Zhang J, Tang S, Wang J, Liu T, Zeng R, Zhu W, Zhang K, Wu J
Immunobiology 2021 Sep;226(5):152124
Immunobiology 2021 Sep;226(5):152124
Penetration Cascade of Size Switchable Nanosystem in Desmoplastic Stroma for Improved Pancreatic Cancer Therapy.
Zhao X, Yang X, Wang X, Zhao X, Zhang Y, Liu S, Anderson GJ, Kim SJ, Li Y, Nie G
ACS nano 2021 Sep 28;15(9):14149-14161
ACS nano 2021 Sep 28;15(9):14149-14161
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload.
Zou Y, Pan L, Shen Y, Wang X, Huang C, Wang H, Jin X, Yin C, Wang Y, Jia J, Qian J, Zou Y, Gong H, Ge J
Cell death & disease 2021 Sep 25;12(10):877
Cell death & disease 2021 Sep 25;12(10):877
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Lam HYP, Yang TH, Liang TR, Cheng PC, Chang KC, Peng SY
Acta tropica 2021 Oct;222:106033
Acta tropica 2021 Oct;222:106033
Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.
Shen L, Song X, Xu Y, Tian R, Wang Y, Li P, Li J, Bai H, Zhu H, Wang D
Engineering in life sciences 2021 Oct;21(10):683-692
Engineering in life sciences 2021 Oct;21(10):683-692
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Zhao K, Yang C, Zhang J, Sun W, Zhou B, Kong X, Shi J
Cell death discovery 2021 Oct 13;7(1):291
Cell death discovery 2021 Oct 13;7(1):291
Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.
Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694
Journal of ginseng research 2021 Nov;45(6):683-694
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Li X, Zhang F, Qu L, Xie Y, Ruan Y, Guo Z, Mao Y, Zou Q, Shi M, Xiao Y, Wang Y, Zhou Y, Guo B
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Injectable self-assembling peptide nanofiber hydrogel as a bioactive 3D platform to promote chronic wound tissue regeneration.
Lou P, Liu S, Wang Y, Pan C, Xu X, Zhao M, Liao G, Yang G, Yuan Y, Li L, Zhang J, Chen Y, Cheng J, Lu Y, Liu J
Acta biomaterialia 2021 Nov;135:100-112
Acta biomaterialia 2021 Nov;135:100-112
Exosomal MicroRNA-21 Promotes Keloid Fibroblast Proliferation and Collagen Production by Inhibiting Smad7.
Li Q, Fang L, Chen J, Zhou S, Zhou K, Cheng F, Cen Y, Qing Y, Wu J
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
Journal of burn care & research : official publication of the American Burn Association 2021 Nov 24;42(6):1266-1274
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
Ge S, Yang W, Chen H, Yuan Q, Liu S, Zhao Y, Zhang J
International journal of molecular sciences 2021 Nov 17;22(22)
International journal of molecular sciences 2021 Nov 17;22(22)
Lipoxin A4 inhibits ovalbumin-induced airway inflammation and airway remodeling in a mouse model of asthma.
Liu Y, Wei L, He C, Chen R, Meng L
Chemico-biological interactions 2021 Nov 1;349:109660
Chemico-biological interactions 2021 Nov 1;349:109660
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Li N, Ouyang Y, Xu X, Yuan Z, Liu C, Zhu Z
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Fluorofenidone inhibits epithelial-mesenchymal transition in human lens epithelial cell line FHL 124: a promising therapeutic strategy against posterior capsular opacification.
Zhuang H, Zheng NX, Lin L, Zhang WZ, Zhang WY, Yu QQ, Xu W
Arquivos brasileiros de oftalmologia 2021 May-Jun;84(3):258-266
Arquivos brasileiros de oftalmologia 2021 May-Jun;84(3):258-266
Splicing factor SRSF6 mediates pleural fibrosis.
Liang LM, Xiong L, Cheng PP, Chen SJ, Feng X, Zhou YY, Niu Q, Wang M, Chen Q, Song LJ, Yu F, He XL, Xiang F, Wang X, Ye H, Ma WL
JCI insight 2021 May 24;6(10)
JCI insight 2021 May 24;6(10)
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, Wei L, Wu H, Liang B, Li H, Huang Y, Lu L, Yang Z, Xian S, Wang L
Cell death & disease 2021 May 11;12(5):470
Cell death & disease 2021 May 11;12(5):470
Dopamine receptor D2 inhibition alleviates diabetic hepatic stellate cells fibrosis by regulating the TGF-β1/Smads and NFκB pathways.
Zhao B, Li S, Guo Z, Chen Z, Zhang X, Xu C, Chen J, Wei C
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
Clinical and experimental pharmacology & physiology 2021 Mar;48(3):370-380
ADAMTS13 inhibits oxidative stress and ameliorates progressive chronic kidney disease following ischaemia/reperfusion injury.
Zhou S, Guo J, Zhao L, Liao Y, Zhou Q, Cui Y, Hu W, Chen J, Ren X, Wei Q, Jiang S, Zheng Y, Li L, Wilcox CS, Persson PB, Patzak A, Tian J, Yin Lai E
Acta physiologica (Oxford, England) 2021 Mar;231(3):e13586
Acta physiologica (Oxford, England) 2021 Mar;231(3):e13586
Umbilical cord-derived mesenchymal stem cells exert anti-fibrotic action on hypertrophic scar-derived fibroblasts in co-culture by inhibiting the activation of the TGF β1/Smad3 pathway.
Meng X, Gao X, Chen X, Yu J
Experimental and therapeutic medicine 2021 Mar;21(3):210
Experimental and therapeutic medicine 2021 Mar;21(3):210
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
SAIL: a new conserved anti-fibrotic lncRNA in the heart.
Luo S, Zhang M, Wu H, Ding X, Li D, Dong X, Hu X, Su S, Shang W, Wu J, Xiao H, Yang W, Zhang Q, Zhang J, Lu Y, Pan Z
Basic research in cardiology 2021 Mar 6;116(1):15
Basic research in cardiology 2021 Mar 6;116(1):15
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway.
Liang J, Yuan H, Xu L, Wang F, Bao X, Yan Y, Wang H, Zhang C, Jin R, Ma L, Zhang J, Huri L, Su X, Xiao R, Ma Y
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):775-785
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):775-785
Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.
Han D, Xu Y, Peng WP, Feng F, Wang Z, Gu C, Zhou X
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Medical science monitor : international medical journal of experimental and clinical research 2021 Mar 12;27:e928547
Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency.
Zhang S, Huang B, Su P, Chang Q, Li P, Song A, Zhao X, Yuan Z, Tan J
Stem cell research & therapy 2021 Mar 12;12(1):178
Stem cell research & therapy 2021 Mar 12;12(1):178
WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.
Sun C, Ma Q, Yin J, Zhang H, Liu X
Experimental & molecular medicine 2021 Jun;53(6):1068-1079
Experimental & molecular medicine 2021 Jun;53(6):1068-1079
HIF-1α is necessary for activation and tumour-promotion effect of cancer-associated fibroblasts in lung cancer.
Zhang Y, Bian Y, Wang Y, Wang Y, Duan X, Han Y, Zhang L, Wang F, Gu Z, Qin Z
Journal of cellular and molecular medicine 2021 Jun;25(12):5457-5469
Journal of cellular and molecular medicine 2021 Jun;25(12):5457-5469
Role and mechanism of TXNIP in ageing-related renal fibrosis.
He Q, Li Y, Zhang W, Chen J, Deng W, Liu Q, Liu Y, Liu D
Mechanisms of ageing and development 2021 Jun;196:111475
Mechanisms of ageing and development 2021 Jun;196:111475
Pre-emptive pharmacological inhibition of fatty acid-binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism.
Chen Y, Dai Y, Song K, Huang Y, Zhang L, Zhang C, Yan Q, Gao H
Cell death & disease 2021 Jun 3;12(6):572
Cell death & disease 2021 Jun 3;12(6):572
Comparison of chondrogenesis-related biological behaviors between human urine-derived stem cells and human bone marrow mesenchymal stem cells from the same individual.
Sun J, Xing F, Zou M, Gong M, Li L, Xiang Z
Stem cell research & therapy 2021 Jun 28;12(1):366
Stem cell research & therapy 2021 Jun 28;12(1):366
Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition.
Wei J, Zhao Q, Yang G, Huang R, Li C, Qi Y, Hao C, Yao W
Journal of cellular and molecular medicine 2021 Jun 2;25(13):6417-28
Journal of cellular and molecular medicine 2021 Jun 2;25(13):6417-28
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Xi X, Zhao Y, Liu H, Li Z, Chen S, Liu D
Experimental cell research 2021 Jun 15;403(2):112598
Experimental cell research 2021 Jun 15;403(2):112598
Vincristine attenuates cardiac fibrosis through the inhibition of NLRP3 inflammasome activation.
Ge C, Cheng Y, Fan Y, He Y
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Clinical science (London, England : 1979) 2021 Jun 11;135(11):1409-1426
Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury.
Lee HJ, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, Salmon AB, Ikeno Y, Ross C, O'Connor CL, Ju W, Bitzer M, Chen Y, Choudhury GG, Singh BB, Sharma K, Kasinath BS
Aging cell 2021 Jul;20(7):e13407
Aging cell 2021 Jul;20(7):e13407
Periplocymarin protects against myocardial fibrosis induced by β-adrenergic activation in mice.
Yun W, Qian L, Yuan R, Xu H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jul;139:111562
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Liu J, Jin Y, Wang B, Zhang J, Zuo S
FEBS open bio 2021 Jul;11(7):2033-2040
FEBS open bio 2021 Jul;11(7):2033-2040
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Liu J, Jin Y, Wang B, Wang Y, Zuo S, Zhang J
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Huoxin Pill inhibits isoproterenol-induced transdifferentiation and collagen synthesis in cardiac fibroblasts through the TGF-β/Smads pathway.
Peng M, Yang M, Lu Y, Lin S, Gao H, Xie L, Huang B, Chen D, Shen A, Shen Z, Peng J, Chu J
Journal of ethnopharmacology 2021 Jul 15;275:114061
Journal of ethnopharmacology 2021 Jul 15;275:114061
SPP1 derived from silica-exposed macrophage exosomes triggers fibroblast transdifferentiation.
Huang R, Hao C, Wang D, Zhao Q, Li C, Wang C, Yao W
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Toxicology and applied pharmacology 2021 Jul 1;422:115559
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Liu J, Peng D, You J, Zhou O, Qiu H, Hao C, Chen H, Fu Z, Zou L
Stem cells and development 2021 Jul 1;30(13):660-670
Stem cells and development 2021 Jul 1;30(13):660-670
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Lin J, Deng H, Zhang Y, Zou L, Fu Z, Dai J
Pediatric pulmonology 2021 Jan;56(1):129-137
Pediatric pulmonology 2021 Jan;56(1):129-137
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, Huang Q, Wei J
Cell biochemistry and function 2021 Jan;39(1):77-87
Cell biochemistry and function 2021 Jan;39(1):77-87
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.
Lv W, Wu M, Ren Y, Luo X, Hu W, Zhang Q, Wu Y
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
Citrate regulates extracellular matrix mineralization during osteoblast differentiation in vitro.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
Journal of inorganic biochemistry 2021 Jan;214:111269
Journal of inorganic biochemistry 2021 Jan;214:111269
Naringin attenuates renal interstitial fibrosis by regulating the TGF-β/Smad signaling pathway and inflammation.
Wang R, Wu G, Dai T, Lang Y, Chi Z, Yang S, Dong D
Experimental and therapeutic medicine 2021 Jan;21(1):66
Experimental and therapeutic medicine 2021 Jan;21(1):66
Responsive and activable nanomedicines for remodeling the tumor microenvironment.
Zhang Y, Han X, Nie G
Nature protocols 2021 Jan;16(1):405-430
Nature protocols 2021 Jan;16(1):405-430
Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension.
Sun X, Zhou M, Wen G, Huang Y, Wu J, Peng L, Jiang W, Yuan H, Lu Y, Cai J
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
Journal of the American Heart Association 2021 Jan 5;10(1):e016364
Bortezomib limits renal allograft interstitial fibrosis by inhibiting NF-κB/TNF-α/Akt/mTOR/P70S6K/Smurf2 pathway via IκBα protein stabilization.
Suo C, Gui Z, Wang Z, Zhou J, Zheng M, Chen H, Fei S, Gu M, Tan R
Clinical science (London, England : 1979) 2021 Jan 15;135(1):53-69
Clinical science (London, England : 1979) 2021 Jan 15;135(1):53-69
lncRNA NEAT1 ameliorates LPS‑induced inflammation in MG63 cells by activating autophagy and suppressing the NLRP3 inflammasome.
Dai W, Wang M, Wang P, Wen J, Wang J, Cha S, Xiao X, He Y, Shu R, Bai D
International journal of molecular medicine 2021 Feb;47(2):607-620
International journal of molecular medicine 2021 Feb;47(2):607-620
Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts.
Li T, Zhuang Y, Yang W, Xie Y, Shang W, Su S, Dong X, Wu J, Jiang W, Zhou Y, Li Y, Zhou X, Zhang M, Lu Y, Pan Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21162
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Luteolin attenuates angiotensin II‑induced renal damage in apolipoprotein E‑deficient mice.
Liu YS, Yang Q, Li S, Luo L, Liu HY, Li XY, Gao ZN
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Proximal tubular epithelial insulin receptor mediates high-fat diet-induced kidney injury.
Lee HJ, Mariappan MM, Norton L, Bakewell T, Feliers D, Oh SB, Donati A, Rubannelsonkumar CS, Venkatachalam MA, Harris SE, Rubera I, Tauc M, Ghosh Choudhury G, Kahn CR, Sharma K, DeFronzo RA, Kasinath BS
JCI insight 2021 Feb 8;6(3)
JCI insight 2021 Feb 8;6(3)
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats.
An R, Wang X, Yang L, Zhang J, Wang N, Xu F, Hou Y, Zhang H, Zhang L
Toxicology 2021 Feb 15;449:152665
Toxicology 2021 Feb 15;449:152665
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
Wang R, Peng L, Lv D, Shang F, Yan J, Li G, Li D, Ouyang J, Yang J
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Journal of cardiovascular pharmacology 2021 Feb 1;77(2):189-199
Ginsenoside Rb1 attenuates age-associated vascular impairment by modulating the Gas6 pathway.
Ke S, Wu L, Wang M, Liu D, Shi G, Zhu J, Qian X
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Pharmaceutical biology 2021 Dec;59(1):1369-1377
Epigallocatechin gallate (EGCG) attenuates myocardial hypertrophy and fibrosis induced by transverse aortic constriction via inhibiting the Akt/mTOR pathway.
Cui Y, Wang Y, Liu G
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Pharmaceutical biology 2021 Dec;59(1):1305-1313
Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β-catenin signaling.
Wang Q, Ma E, Wo D, Chen J, He J, Peng J, Zhu W, Ren DN
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Journal of cellular and molecular medicine 2021 Dec;25(24):11053-11062
Adipose-derived mesenchymal stem cell exosomes inhibit transforming growth factor-β1-induced collagen synthesis in oral mucosal fibroblasts.
Liu J, Li F, Liu B, Yao Z, Li L, Liu G, Peng L, Wang Y, Huang J
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Experimental and therapeutic medicine 2021 Dec;22(6):1419
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
Zhao K, Mao Y, Ye X, Ma J, Sun L, Li P, Li Y
European journal of pharmacology 2021 Dec 5;912:174587
European journal of pharmacology 2021 Dec 5;912:174587
The application of human periodontal ligament stem cells and biomimetic silk scaffold for in situ tendon regeneration.
Chen J, Mo Q, Sheng R, Zhu A, Ling C, Luo Y, Zhang A, Chen Z, Yao Q, Cai Z, Zhang W
Stem cell research & therapy 2021 Dec 4;12(1):596
Stem cell research & therapy 2021 Dec 4;12(1):596
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Wu Y, Qi Y, Qiu Z, Chen W
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity.
Fujimoto Y, Kaji K, Nishimura N, Enomoto M, Murata K, Takeda S, Takaya H, Kawaratani H, Moriya K, Namisaki T, Akahane T, Yoshiji H
World journal of gastroenterology 2021 Dec 28;27(48):8323-8342
World journal of gastroenterology 2021 Dec 28;27(48):8323-8342
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Li B, Mu M, Sun Q, Cao H, Liu Q, Liu J, Zhang J, Xu K, Hu D, Tao X, Wang J
Toxicology letters 2021 Dec 15;353:1-12
Toxicology letters 2021 Dec 15;353:1-12
Gsα deficiency facilitates cardiac remodeling via CREB/ Bmp10-mediated signaling.
Yin P, Li D, Zhao Q, Cai M, Wu Z, Shi Y, Su L
Cell death discovery 2021 Dec 14;7(1):391
Cell death discovery 2021 Dec 14;7(1):391
Enzymatically crosslinked silk-nanosilicate reinforced hydrogel with dual-lineage bioactivity for osteochondral tissue engineering.
Zhang W, Zhang Y, Zhang A, Ling C, Sheng R, Li X, Yao Q, Chen J
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112215
Materials science & engineering. C, Materials for biological applications 2021 Aug;127:112215
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity.
Cutolo M, Gotelli E, Montagna P, Tardito S, Paolino S, Pizzorni C, Sulli A, Smith V, Soldano S
Arthritis research & therapy 2021 Aug 3;23(1):205
Arthritis research & therapy 2021 Aug 3;23(1):205
ER-anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6.
Zuo S, Wang B, Liu J, Kong D, Cui H, Jia Y, Wang C, Xu X, Chen G, Wang Y, Yang L, Zhang K, Ai D, Du J, Shen Y, Yu Y
The EMBO journal 2021 Aug 16;40(16):e107403
The EMBO journal 2021 Aug 16;40(16):e107403
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Zhou S, He Y, Zhang W, Xiong Y, Jiang L, Wang J, Cui X, Qu Y, Ge F
Journal of ethnopharmacology 2021 Aug 10;276:114189
Journal of ethnopharmacology 2021 Aug 10;276:114189
Adenosine A3 receptor activated in H(2)O(2) oxidative stress of primary open-angle glaucoma.
Zhou Z, Gao Z, Yan W, Zhang Y, Huang J, Xiong K
Annals of translational medicine 2021 Apr;9(7):526
Annals of translational medicine 2021 Apr;9(7):526
Matrine attenuates pathological cardiac fibrosis via RPS5/p38 in mice.
Zhang X, Hu C, Zhang N, Wei WY, Li LL, Wu HM, Ma ZG, Tang QZ
Acta pharmacologica Sinica 2021 Apr;42(4):573-584
Acta pharmacologica Sinica 2021 Apr;42(4):573-584
Overexpression of Fgf8 in the epidermis inhibits hair follicle development.
Wang Z, Chen Y, Chen M, Zhang Y
Experimental dermatology 2021 Apr;30(4):494-502
Experimental dermatology 2021 Apr;30(4):494-502
Endogenous production of n-3 polyunsaturated fatty acids protects mice from carbon tetrachloride-induced liver fibrosis by regulating mTOR and Bcl-2/Bax signalling pathways.
Shan C, Wang R, Wang S, Zhang Z, Xing C, Feng W, Zhao Z, Zhou S, Zhao AZ, Mu Y, Li F
Experimental physiology 2021 Apr;106(4):983-993
Experimental physiology 2021 Apr;106(4):983-993
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
The Antiproliferative and Antifibrotic Effects of Cisplatin on Primary Human Vocal Fold Fibroblasts.
Xu H, Wang Q, Fan GK
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
ORL; journal for oto-rhino-laryngology and its related specialties 2020;82(4):188-200
CDKN2a/p16 Antagonizes Hepatic Stellate Cell Activation and Liver Fibrosis by Modulating ROS Levels.
Lv F, Li N, Kong M, Wu J, Fan Z, Miao D, Xu Y, Ye Q, Wang Y
Frontiers in cell and developmental biology 2020;8:176
Frontiers in cell and developmental biology 2020;8:176
Ginsenoside Rb1 Ameliorates Age-Related Myocardial Dysfunction by Regulating the NF-κB Signaling Pathway.
Ke SY, Liu DH, Wu L, Yu XG, Wang M, Shi GY, Wen RH, Zhou B, Hao BS, Liu Y, Zhu JM, Qian XX
The American journal of Chinese medicine 2020;48(6):1369-1383
The American journal of Chinese medicine 2020;48(6):1369-1383
Protective Effects of MitoTEMPO on Nonalcoholic Fatty Liver Disease via Regulating Myeloid-Derived Suppressor Cells and Inflammation in Mice.
Wu J, Zheng L, Mo J, Yao X, Fan C, Bao Y
BioMed research international 2020;2020:9329427
BioMed research international 2020;2020:9329427
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, Chen Z, Wang S, Liu J
Oxidative medicine and cellular longevity 2020;2020:6834236
Oxidative medicine and cellular longevity 2020;2020:6834236
Exposure to Air Pollution Exacerbates Inflammation in Rats with Preexisting COPD.
Wang J, Li Y, Zhao P, Tian Y, Liu X, He H, Jia R, Oliver BG, Li J
Mediators of inflammation 2020;2020:4260204
Mediators of inflammation 2020;2020:4260204
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Gu J, Chen C, Wang J, Chen T, Yao W, Yan T, Liu Z
Oxidative medicine and cellular longevity 2020;2020:2452848
Oxidative medicine and cellular longevity 2020;2020:2452848
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
Resveratrol promotes osteoblastic differentiation in a rat model of postmenopausal osteoporosis by regulating autophagy.
Wang W, Zhang LM, Guo C, Han JF
Nutrition & metabolism 2020;17:29
Nutrition & metabolism 2020;17:29
Galectin-3 Induces Atrial Fibrosis by Activating the TGF-β1/Smad Pathway in Patients with Atrial Fibrillation.
Xiao M, Zhang M, Bie M, Wang X, Guo J, Xiao H
Cardiology 2020;145(7):446-455
Cardiology 2020;145(7):446-455
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
Yan M, Shen M, Xu L, Huang J, He G, An M, Li X, Gao Z, Meng X
OncoTargets and therapy 2020;13:9455-9463
OncoTargets and therapy 2020;13:9455-9463
Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation.
Wu SJ, Lin ZH, Lin YZ, Rao ZH, Lin JF, Wu LP, Li L
Frontiers in physiology 2020;11:33
Frontiers in physiology 2020;11:33
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
Li L, Nie X, Yi M, Qin W, Li F, Wu B, Yuan X
Frontiers in oncology 2020;10:528686
Frontiers in oncology 2020;10:528686
Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.
Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y
Cell death and differentiation 2020 Sep;27(9):2605-2619
Cell death and differentiation 2020 Sep;27(9):2605-2619
miR-26a attenuates cardiac apoptosis and fibrosis by targeting ataxia-telangiectasia mutated in myocardial infarction.
Chiang MH, Liang CJ, Lin LC, Yang YF, Huang CC, Chen YH, Kao HL, Chen YC, Ke SR, Lee CW, Lin MS, Chen YL
Journal of cellular physiology 2020 Sep;235(9):6085-6102
Journal of cellular physiology 2020 Sep;235(9):6085-6102
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
Wang X, Li D, Wu H, Liu F, Liu F, Zhang Q, Li J
Mechanisms of ageing and development 2020 Sep;190:111293
Mechanisms of ageing and development 2020 Sep;190:111293
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β(1)/Smad3 signaling pathway to inhibit ovarian fibrosis to repair ovarian function in POI rats.
Cui L, Bao H, Liu Z, Man X, Liu H, Hou Y, Luo Q, Wang S, Fu Q, Zhang H
Stem cell research & therapy 2020 Sep 7;11(1):386
Stem cell research & therapy 2020 Sep 7;11(1):386
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Wang Z, Zhao Y, Zhao H, Zhou J, Feng D, Tang F, Li Y, Lv L, Chen Z, Ma X, Tian X, Yao J
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Polystyrene microplastics cause cardiac fibrosis by activating Wnt/β-catenin signaling pathway and promoting cardiomyocyte apoptosis in rats.
Li Z, Zhu S, Liu Q, Wei J, Jin Y, Wang X, Zhang L
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):115025
MSC-derived exosomes protect against oxidative stress-induced skin injury via adaptive regulation of the NRF2 defense system.
Wang T, Jian Z, Baskys A, Yang J, Li J, Guo H, Hei Y, Xian P, He Z, Li Z, Li N, Long Q
Biomaterials 2020 Oct;257:120264
Biomaterials 2020 Oct;257:120264
Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells.
Kong H, He J, Guo S, Song Q, Xiang D, Tao R, Yu H, Chen G, Huang Z, Ning Q, Huang J
PLoS pathogens 2020 Oct;16(10):e1008947
PLoS pathogens 2020 Oct;16(10):e1008947
Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, Zhu L, Yao X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110522
TGFβ acts through PDGFRβ to activate mTORC1 via the Akt/PRAS40 axis and causes glomerular mesangial cell hypertrophy and matrix protein expression.
Maity S, Das F, Kasinath BS, Ghosh-Choudhury N, Ghosh Choudhury G
The Journal of biological chemistry 2020 Oct 16;295(42):14262-14278
The Journal of biological chemistry 2020 Oct 16;295(42):14262-14278
MAD2B contributes to parietal epithelial cell activation and crescentic glomerulonephritis via Skp2.
Ye C, Xiong W, Lei CT, Tang H, Su H, Yi F, Zhang C
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
American journal of physiology. Renal physiology 2020 Oct 1;319(4):F636-F646
Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.
Cheng H, Wu X, Ni G, Wang S, Peng W, Zhang H, Gao J, Li X
Annals of translational medicine 2020 Nov;8(21):1396
Annals of translational medicine 2020 Nov;8(21):1396
Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis.
Liu F, Yu F, Lu YZ, Cheng PP, Liang LM, Wang M, Chen SJ, Huang Y, Song LJ, He XL, Xiong L, Xin JB, Ma WL, Ye H
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Biochimica et biophysica acta. Molecular cell research 2020 Nov;1867(11):118806
Magnesium Calcium Phosphate Cement Incorporating Citrate for Vascularized Bone Regeneration.
Wu X, Dai H, Yu S, Zhao Y, Long Y, Li W, Tu J
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
ACS biomaterials science & engineering 2020 Nov 9;6(11):6299-6308
Involvement of FATP2-mediated tubular lipid metabolic reprogramming in renal fibrogenesis.
Chen Y, Yan Q, Lv M, Song K, Dai Y, Huang Y, Zhang L, Zhang C, Gao H
Cell death & disease 2020 Nov 20;11(11):994
Cell death & disease 2020 Nov 20;11(11):994
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function.
Sudhahar V, Okur MN, O'Bryan JP, Minshall RD, Fulton D, Ushio-Fukai M, Fukai T
American journal of physiology. Cell physiology 2020 Nov 1;319(5):C933-C944
American journal of physiology. Cell physiology 2020 Nov 1;319(5):C933-C944
Inhibition of miR-182-5p attenuates pulmonary fibrosis via TGF-β/Smad pathway.
Chen Y, Zhang Q, Zhou Y, Yang Z, Tan M
Human & experimental toxicology 2020 May;39(5):683-695
Human & experimental toxicology 2020 May;39(5):683-695
TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, Yu Q, Zhou Y, Zhang J, Chen J, Ji J, Chen K, Wang F, Dai W, Fan X, Guo C
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Journal of cellular and molecular medicine 2020 May;24(9):5224-5237
Melatonin up-regulates bone marrow mesenchymal stem cells osteogenic action but suppresses their mediated osteoclastogenesis via MT(2) -inactivated NF-κB pathway.
Zhou Y, Wang C, Si J, Wang B, Zhang D, Ding D, Zhang J, Wang H
British journal of pharmacology 2020 May;177(9):2106-2122
British journal of pharmacology 2020 May;177(9):2106-2122
Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models.
Liu YC, Wang HL, Huang YZ, Weng YH, Chen RS, Tsai WC, Yeh TH, Lu CS, Chen YL, Lin YW, Chen YJ, Hsu CC, Chiu CH, Chiu CC
Biochemical pharmacology 2020 May;175:113919
Biochemical pharmacology 2020 May;175:113919
Comprehensive circRNA expression profile and construction of circRNA-related ceRNA network in cardiac fibrosis.
Gu X, Jiang YN, Wang WJ, Zhang J, Shang DS, Sun CB, Tian JT, Tian JW, Yu B, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109944
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:109944
Lactoferrin Contributes a Renoprotective Effect in Acute Kidney Injury and Early Renal Fibrosis.
Hsu YH, Chiu IJ, Lin YF, Chen YJ, Lee YH, Chiu HW
Pharmaceutics 2020 May 8;12(5)
Pharmaceutics 2020 May 8;12(5)
HUWE1 promotes EGFR ubiquitination and degradation to protect against renal tubulointerstitial fibrosis.
Zhu Q, Dong H, Bukhari AA, Zhao A, Li M, Sun Y, Zhang X, Cao C, Su D, Liang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4591-4601
G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.
Lai S, Fu X, Yang S, Zhang S, Lin Q, Zhang M, Chen H
Journal of diabetes 2020 Mar;12(3):247-258
Journal of diabetes 2020 Mar;12(3):247-258
Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing.
Liu Q, Wen Y, Qiu J, Zhang Z, Jin Z, Cao M, Jiao Y, Yang H
Heliyon 2020 Jun;6(6):e04347
Heliyon 2020 Jun;6(6):e04347
Epithelial-mesenchymal transition and metastasis of colon cancer cells induced by the FAK pathway in cancer-associated fibroblasts.
Xuefeng X, Hou MX, Yang ZW, Agudamu A, Wang F, Su XL, Li X, Shi L, Terigele T, Bao LL, Wu XL
The Journal of international medical research 2020 Jun;48(6):300060520931242
The Journal of international medical research 2020 Jun;48(6):300060520931242
Meprin-α (Mep1A) enhances TNF-α secretion by mast cells and aggravates abdominal aortic aneurysms.
Gao R, Liu D, Guo W, Ge W, Fan T, Li B, Gao P, Liu B, Zheng Y, Wang J
British journal of pharmacology 2020 Jun;177(12):2872-2885
British journal of pharmacology 2020 Jun;177(12):2872-2885
LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p.
Wang J, Zhang S, Li X, Gong M
Aging 2020 Jun 6;12(11):10441-10456
Aging 2020 Jun 6;12(11):10441-10456
High expression of AMAP1, an ARF6 effector, is associated with elevated levels of PD-L1 and fibrosis of pancreatic cancer.
Tsutaho A, Hashimoto A, Hashimoto S, Hata S, Kachi S, Hirano S, Sabe H
Cell communication and signaling : CCS 2020 Jun 24;18(1):101
Cell communication and signaling : CCS 2020 Jun 24;18(1):101
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, Yang Y, Lu J, Pei G
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Si-Miao-Yong-An decoction attenuates cardiac fibrosis via suppressing TGF-β1 pathway and interfering with MMP-TIMPs expression.
Su C, Wang Q, Luo H, Jiao W, Tang J, Li L, Tian L, Chen X, Liu B, Yu X, Li S, Guo S, Wang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jul;127:110132
Design, synthesis and discovery of 2(1H)-quinolone derivatives for the treatment of pulmonary fibrosis through inhibition of TGF-β/smad dependent and independent pathway.
Xue L, Deng D, Zheng S, Tang M, Yang Z, Pei H, Chen Y, Yang T, Liu K, Ye H, Chen L
European journal of medicinal chemistry 2020 Jul 1;197:112259
European journal of medicinal chemistry 2020 Jul 1;197:112259
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X
International journal of molecular medicine 2020 Jan;45(1):175-185
International journal of molecular medicine 2020 Jan;45(1):175-185
Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.
Du MY, Duan JX, Zhang CY, Yang HH, Guan XX, Zhong WJ, Liu YZ, Li ZM, Cheng YR, Zhou Y, Guan CX
Cell biology international 2020 Jan;44(1):98-107
Cell biology international 2020 Jan;44(1):98-107
Left Atrial Appendage Fibrosis and 3-Year Clinical Outcomes in Atrial Fibrillation After Endoscopic Ablation: A Histologic Analysis.
Ma N, Lu R, Zhao D, Jiang Z, Tang M, Bao C, Mei J
The Annals of thoracic surgery 2020 Jan;109(1):69-76
The Annals of thoracic surgery 2020 Jan;109(1):69-76
The Effect of Mitomycin C on Reducing Endometrial Fibrosis for Intrauterine Adhesion.
Xu F, Shen X, Sun C, Xu X, Wang W, Zheng J
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 2;26:e920670
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 2;26:e920670
Fibroblasts Derived From Human Adipose Stem Cells Produce More Effective Extracellular Matrix and Migrate Faster Compared to Primary Dermal Fibroblasts.
Gersch RP, Raum JC, Calvert C, Percec I
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
Aesthetic surgery journal 2020 Jan 1;40(1):108-117
Synthesis and discovery of new compounds bearing coumarin scaffold for the treatment of pulmonary fibrosis.
Deng D, Pei H, Lan T, Zhu J, Tang M, Xue L, Yang Z, Zheng S, Ye H, Chen L
European journal of medicinal chemistry 2020 Jan 1;185:111790
European journal of medicinal chemistry 2020 Jan 1;185:111790
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Zhang N, Zhang Y, Wu B, You S, Sun Y
Redox biology 2020 Feb;30:101419
Redox biology 2020 Feb;30:101419
N(6)-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon black particles in rats.
Han B, Chu C, Su X, Zhang N, Zhou L, Zhang M, Yang S, Shi L, Zhao B, Niu Y, Zhang R
Nanotoxicology 2020 Feb;14(1):1-20
Nanotoxicology 2020 Feb;14(1):1-20
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X
Cell death & disease 2020 Feb 24;11(2):146
Cell death & disease 2020 Feb 24;11(2):146
Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis.
Wang D, Wang T, Wang R, Zhang X, Wang L, Xiang Z, Zhuang L, Shen S, Wang H, Gao Q, Wang Y
Journal of translational medicine 2020 Feb 17;18(1):84
Journal of translational medicine 2020 Feb 17;18(1):84
An all-silk-derived functional nanosphere matrix for sequential biomolecule delivery and in situ osteochondral regeneration.
Zhang W, Ling C, Zhang A, Liu H, Jiang Y, Li X, Sheng R, Yao Q, Chen J
Bioactive materials 2020 Dec;5(4):832-843
Bioactive materials 2020 Dec;5(4):832-843
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
Cutolo M, Soldano S, Montagna P, Martinelli G, Tardito S, Corallo C, Giordano N, Tavilla P, Cozzani E, Parodi A, Sulli A, Pizzorni C, Patane M, Smith V, Paolino S
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage.
Zhang J, Ge J, Xu Y, Chen J, Zhou A, Sun L, Gao Y, Zhang Y, Gu T, Ning X
International journal of biological macromolecules 2020 Dec 1;164:4466-4474
International journal of biological macromolecules 2020 Dec 1;164:4466-4474
Morroniside attenuates high glucose-induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis.
Sun Y, Zhu Y, Liu X, Chai Y, Xu J
Cell proliferation 2020 Aug;53(8):e12866
Cell proliferation 2020 Aug;53(8):e12866
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, Feng J, Ye Q, Li J, Li G, Fan Z
International journal of molecular medicine 2020 Aug;46(2):633-640
International journal of molecular medicine 2020 Aug;46(2):633-640
Biomineralizaion of hydroxyapatite on polyethylene terephthalate artificial ligaments promotes graft-bone healing after anterior cruciate ligament reconstruction: An in vitro and in vivo study.
Cai J, Ai C, Chen J, Chen S
Journal of biomaterials applications 2020 Aug;35(2):193-204
Journal of biomaterials applications 2020 Aug;35(2):193-204
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Wu L, Mo W, Feng J, Li J, Yu Q, Li S, Zhang J, Chen K, Ji J, Dai W, Wu J, Xu X, Mao Y, Guo C
British journal of pharmacology 2020 Aug;177(16):3760-3777
British journal of pharmacology 2020 Aug;177(16):3760-3777
Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit.
Xu HL, Yang WG, Chen PP, Chen R, Xue PP, Wang LF, Yuan JD, Yao Q, Chen B, Zhao YZ
Biotechnology journal 2020 Aug;15(8):e2000004
Biotechnology journal 2020 Aug;15(8):e2000004
Isoliquiritigenin inhibits TGF-β1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells.
He J, Peng H, Wang M, Liu Y, Guo X, Wang B, Dai L, Cheng X, Meng Z, Yuan L, Cai F, Tang Y
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):810-820
Acta biochimica et biophysica Sinica 2020 Aug 5;52(8):810-820
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
A novel knitted scaffold made of microfiber/nanofiber core-sheath yarns for tendon tissue engineering.
Cai J, Xie X, Li D, Wang L, Jiang J, Mo X, Zhao J
Biomaterials science 2020 Aug 11;8(16):4413-4425
Biomaterials science 2020 Aug 11;8(16):4413-4425
RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice.
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, Cheng Q, Xu D, Xie H, Chen P, Zheng P, Zhang Y, Zhou L, Zhang W, Yu C, Liu J, Lu L
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Journal of molecular medicine (Berlin, Germany) 2020 Apr;98(4):527-540
Pharmacologic inhibition of RGD-binding integrins ameliorates fibrosis and improves function following kidney injury.
Basta J, Robbins L, Stout L, Prinsen MJ, Griggs DW, Rauchman M
Physiological reports 2020 Apr;8(7):e14329
Physiological reports 2020 Apr;8(7):e14329
LncRNA MIAT/miR-133a-3p axis regulates atrial fibrillation and atrial fibrillation-induced myocardial fibrosis.
Yao L, Zhou B, You L, Hu H, Xie R
Molecular biology reports 2020 Apr;47(4):2605-2617
Molecular biology reports 2020 Apr;47(4):2605-2617
Downregulation of miR-96 suppresses the profibrogenic functions of cardiac fibroblasts induced by angiotensin II and attenuates atrial fibrosis by upregulating KLF13.
Su L, Yao Y, Song W
Human cell 2020 Apr;33(2):337-346
Human cell 2020 Apr;33(2):337-346
COX-2/sEH dual inhibitor PTUPB alleviates bleomycin-induced pulmonary fibrosis in mice via inhibiting senescence.
Zhang CY, Duan JX, Yang HH, Sun CC, Zhong WJ, Tao JH, Guan XX, Jiang HL, Hammock BD, Hwang SH, Zhou Y, Guan CX
The FEBS journal 2020 Apr;287(8):1666-1680
The FEBS journal 2020 Apr;287(8):1666-1680
Long-term voluntary running prevents the onset of symptomatic Friedreich's ataxia in mice.
Zhao H, Lewellen BM, Wilson RJ, Cui D, Drake JC, Zhang M, Yan Z
Scientific reports 2020 Apr 8;10(1):6095
Scientific reports 2020 Apr 8;10(1):6095
Septin4 as an autophagy modulator regulates Angiotensin-II mediated VSMCs proliferation and migration.
Wang N, Xu F, Lu S, Zhang N, Sun Y
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Biochemical and biophysical research communications 2020 Apr 30;525(2):272-279
Silica particles disorganize the polarization of pulmonary macrophages in mice.
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, Ding M, Zhao A, Yao W
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Ecotoxicology and environmental safety 2020 Apr 15;193:110364
Dysregulation of the Wnt Signaling Pathway and Synovial Stem Cell Dysfunction in Osteoarthritis Development.
Huang J, Chen C, Liang C, Luo P, Xia G, Zhang L, Wang X, Wen Z, Cao X, Wu S
Stem cells and development 2020 Apr 1;29(7):401-413
Stem cells and development 2020 Apr 1;29(7):401-413
Kartogenin hydrolysis product 4-aminobiphenyl distributes to cartilage and mediates cartilage regeneration.
Zhang S, Hu P, Liu T, Li Z, Huang Y, Liao J, Hamid MR, Wen L, Wang T, Mo C, Alini M, Grad S, Wang T, Chen D, Zhou G
Theranostics 2019;9(24):7108-7121
Theranostics 2019;9(24):7108-7121
Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats.
Zhang Y, Yang J, Zhuan L, Zang G, Wang T, Liu J
PeerJ 2019;7:e7507
PeerJ 2019;7:e7507
Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.
Ban D, Hua S, Zhang W, Shen C, Miao X, Liu W
Cellular & molecular biology letters 2019;24:52
Cellular & molecular biology letters 2019;24:52
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Li Z, Chen D, Jia Y, Feng Y, Wang C, Tong Y, Cui R, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2019;2019:6565283
Oxidative medicine and cellular longevity 2019;2019:6565283
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway.
Milanesi S, Garibaldi S, Saio M, Ghigliotti G, Picciotto D, Ameri P, Garibotto G, Barisione C, Verzola D
Oxidative medicine and cellular longevity 2019;2019:2050183
Oxidative medicine and cellular longevity 2019;2019:2050183
A Biomimetic Model for Mineralization of Type-I Collagen Fibrils.
Yao S, Xu Y, Shao C, Nudelman F, Sommerdijk NAJM, Tang R
Methods in molecular biology (Clifton, N.J.) 2019;1944:39-54
Methods in molecular biology (Clifton, N.J.) 2019;1944:39-54
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
Presence and function of stress granules in atrial fibrillation.
Dong G, Liang F, Sun B, Wang C, Liu Y, Guan X, Yang B, Xiu C, Yang N, Liu F, Lu T, Han W
PloS one 2019;14(4):e0213769
PloS one 2019;14(4):e0213769
A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.
Tran BH, Yu Y, Chang L, Tan B, Jia W, Xiong Y, Dai T, Zhong R, Zhang W, Le VM, Rose P, Wang Z, Mao Y, Zhu YZ
International journal of nanomedicine 2019;14:10061-10077
International journal of nanomedicine 2019;14:10061-10077
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, Liu J
International journal of clinical and experimental pathology 2019;12(3):867-875
International journal of clinical and experimental pathology 2019;12(3):867-875
A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation.
Zhang C, Zhu X, Li L, Ma T, Shi M, Yang Y, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1297-1309
Stachydrine Ameliorates Cardiac Fibrosis Through Inhibition of Angiotensin II/Transformation Growth Factor β1 Fibrogenic Axis.
Liu X, Shan X, Chen H, Li Z, Zhao P, Zhang C, Guo W, Xu M, Lu R
Frontiers in pharmacology 2019;10:538
Frontiers in pharmacology 2019;10:538
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
Shao M, Wen ZB, Yang HH, Zhang CY, Xiong JB, Guan XX, Zhong WJ, Jiang HL, Sun CC, Luo XQ, He XF, Zhou Y, Guan CX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
Rubidium-Containing Calcium Alginate Hydrogel for Antibacterial and Diabetic Skin Wound Healing Applications.
He X, Ding Y, Xie W, Sun R, Hunt NC, Song J, Sun X, Peng C, Zeng Q, Tan Y, Liu Y
ACS biomaterials science & engineering 2019 Sep 9;5(9):4726-4738
ACS biomaterials science & engineering 2019 Sep 9;5(9):4726-4738
lncRNA NR_038323 Suppresses Renal Fibrosis in Diabetic Nephropathy by Targeting the miR-324-3p/DUSP1 Axis.
Ge Y, Wang J, Wu D, Zhou Y, Qiu S, Chen J, Zhu X, Xiang X, Li H, Zhang D
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Molecular therapy. Nucleic acids 2019 Sep 6;17:741-753
Germacrane Sesquiterpenoids as a New Type of Anticardiac Fibrosis Agent Targeting Transforming Growth Factor β Type I Receptor.
Lou LL, Ni FQ, Chen L, Shaker S, Li W, Wang R, Tang GH, Yin S
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Journal of medicinal chemistry 2019 Sep 12;62(17):7961-7975
Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation.
Sun L, Xu T, Chen Y, Qu W, Sun D, Song X, Yuan Q, Yao L
Life sciences 2019 Sep 1;232:116609
Life sciences 2019 Sep 1;232:116609
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
Qu R, Chen X, Yuan Y, Wang W, Qiu C, Liu L, Li P, Zhang Z, Vasilev K, Liu L, Hayball J, Zhao Y, Li Y, Li W
Inflammation 2019 Oct;42(5):1652-1665
Inflammation 2019 Oct;42(5):1652-1665
The effect of topical ramipril and losartan cream in inhibiting scar formation.
Zheng B, Fang QQ, Wang XF, Shi BH, Zhao WY, Chen CY, Zhang MX, Zhang LY, Hu YY, Shi P, Ma L, Tan WQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109394
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Liu ZH, Zhang Y, Wang X, Fan XF, Zhang Y, Li X, Gong YS, Han LP
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Oct;118:109227
Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.
Chen TT, Peng S, Wang Y, Hu Y, Shen Y, Xu Y, Yin J, Liu C, Cao J
Biomolecules 2019 Oct 25;9(11)
Biomolecules 2019 Oct 25;9(11)
Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.
Tan X, Hu L, Shu Z, Chen L, Li X, Du M, Sun D, Mao X, Deng S, Huang K, Zhang F
Diabetes 2019 Nov;68(11):2063-2073
Diabetes 2019 Nov;68(11):2063-2073
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
Gu W, Yuan Y, Wang L, Yang H, Li S, Tang Z, Li Q
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
ClC-3 chloride channels are involved in estradiol regulation of bone formation by MC3T3-E1 osteoblasts.
Deng Z, Li W, Xu J, Yu M, Li D, Tan Q, Wang D, Chen L, Wang L
Journal of cellular biochemistry 2019 May;120(5):8366-8375
Journal of cellular biochemistry 2019 May;120(5):8366-8375
Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro.
Kong D, Zhang D, Cui Q, Wang K, Tang J, Liu Z, Wu G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 May;113:108706
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 May;113:108706
Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.
Gao J, Guo Y, Chen Y, Zhou J, Liu Y, Su P
Gene 2019 May 20;697:11-18
Gene 2019 May 20;697:11-18
Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, Zhang B, Sun C, Ning J, Feng L, Zhang H, Ma X
Toxicology and applied pharmacology 2019 May 15;371:63-73
Toxicology and applied pharmacology 2019 May 15;371:63-73
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H
EBioMedicine 2019 Mar;41:670-682
EBioMedicine 2019 Mar;41:670-682
Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis.
Chen YX, Zhu DY, Gao J, Xu ZL, Tao SC, Yin WJ, Zhang YL, Gao YS, Zhang CQ
The FEBS journal 2019 Mar;286(6):1101-1119
The FEBS journal 2019 Mar;286(6):1101-1119
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, Wang J, Feng X
Pain physician 2019 Mar;22(2):155-164
Pain physician 2019 Mar;22(2):155-164
Citric acid enhances the physical properties, cytocompatibility and osteogenesis of magnesium calcium phosphate cement.
Wang S, Xu C, Yu S, Wu X, Jie Z, Dai H
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Journal of the mechanical behavior of biomedical materials 2019 Jun;94:42-50
Aloe-Emodin Ameliorates Renal Fibrosis Via Inhibiting PI3K/Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Dou F, Liu Y, Liu L, Wang J, Sun T, Mu F, Guo Q, Guo C, Jia N, Liu W, Ding Y, Wen A
Rejuvenation research 2019 Jun;22(3):218-229
Rejuvenation research 2019 Jun;22(3):218-229
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats.
Liu H, Dong Y, Feng X, Li L, Jiao Y, Bai S, Feng Z, Yu H, Li X, Zhao Y
Stem cell research & therapy 2019 Jun 18;10(1):180
Stem cell research & therapy 2019 Jun 18;10(1):180
Induction of Fibrosis and Autophagy in Kidney Cells by Vinyl Chloride.
Hsu YH, Chuang HC, Lee YH, Lin YF, Chiu YJ, Wang YL, Wu MS, Chiu HW
Cells 2019 Jun 17;8(6)
Cells 2019 Jun 17;8(6)
Small molecule inhibitor of TGF-β signaling enables robust osteogenesis of autologous GMSCs to successfully repair minipig severe maxillofacial bone defects.
Shi A, Heinayati A, Bao D, Liu H, Ding X, Tong X, Wang L, Wang B, Qin H
Stem cell research & therapy 2019 Jun 13;10(1):172
Stem cell research & therapy 2019 Jun 13;10(1):172
Aspirin targets P4HA2 through inhibiting NF-κB and LMCD1-AS1/let-7g to inhibit tumour growth and collagen deposition in hepatocellular carcinoma.
Wang T, Fu X, Jin T, Zhang L, Liu B, Wu Y, Xu F, Wang X, Ye K, Zhang W, Ye L
EBioMedicine 2019 Jul;45:168-180
EBioMedicine 2019 Jul;45:168-180
Eliciting α7-nAChR exerts cardioprotective effects on ischemic cardiomyopathy via activation of AMPK signalling.
Lin ZH, Li YC, Wu SJ, Zheng C, Lin YZ, Lian H, Lin WQ, Lin JF
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
Journal of cellular and molecular medicine 2019 Jul;23(7):4746-4758
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, Wei X, Lu S, Bai F, Wang D, Lin X, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Sun J, Su W, Zhao X, Shan T, Jin T, Guo Y, Li C, Li R, Zhou Y, Shan H, Sun X, Liang H
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Role of synovium-derived fibrous cartilage in temporomandibular joint synovial chondromatosis.
Li Y, Feng Y, Cao P, Ke J, Fang W, Cai H, Deng M, Long X
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):79-86
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2019 Jan;48(1):79-86
Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.
Liu T, Xu L, Wang C, Chen K, Xia Y, Li J, Li S, Wu L, Feng J, Xu S, Wang W, Lu X, Fan X, Mo W, Zhou Y, Zhao Y, Guo C
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Journal of gastroenterology and hepatology 2019 Jan;34(1):263-276
Gene-targeted deletion in mice of the Ets-1 transcription factor, a candidate gene in the Jacobsen syndrome kidney "critical region," causes abnormal kidney development.
Ye M, Xu L, Fu M, Chen D, Mattina T, Zufardi O, Rossi E, Bush KT, Nigam SK, Grossfeld P
American journal of medical genetics. Part A 2019 Jan;179(1):71-77
American journal of medical genetics. Part A 2019 Jan;179(1):71-77
Neutralization of IL-18 by IL-18 binding protein ameliorates bleomycin-induced pulmonary fibrosis via inhibition of epithelial-mesenchymal transition.
Zhang LM, Zhang Y, Fei C, Zhang J, Wang L, Yi ZW, Gao G
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Biochemical and biophysical research communications 2019 Jan 8;508(2):660-666
Electrophoretic Deposition of Bioadaptive Drug Delivery Coatings on Magnesium Alloy for Bone Repair.
Qi H, Heise S, Zhou J, Schuhladen K, Yang Y, Cui N, Dong R, Virtanen S, Chen Q, Boccaccini AR, Lu T
ACS applied materials & interfaces 2019 Feb 27;11(8):8625-8634
ACS applied materials & interfaces 2019 Feb 27;11(8):8625-8634
Involvement of serum amyloid A1 in the rupture of fetal membranes through induction of collagen I degradation.
Wang WS, Li WJ, Wang YW, Wang LY, Mi YB, Lu JW, Lu Y, Zhang CY, Sun K
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
Clinical science (London, England : 1979) 2019 Feb 14;133(3):515-530
A Novel Tissue-Engineered Corneal Stromal Equivalent Based on Amniotic Membrane and Keratocytes.
Che X, Wu H, Jia C, Sun H, Ou S, Wang J, Jeyalatha MV, He X, Yu J, Zuo C, Liu Z, Li W
Investigative ophthalmology & visual science 2019 Feb 1;60(2):517-527
Investigative ophthalmology & visual science 2019 Feb 1;60(2):517-527
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.
Meng Y, Pan M, Zheng B, Chen Y, Li W, Yang Q, Zheng Z, Sun N, Zhang Y, Li X
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Antioxidants & redox signaling 2019 Feb 1;30(4):520-541
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Zou LX, Chen C, Yan X, Lin QY, Fang J, Li PB, Han X, Wang QS, Guo SB, Li HH, Zhang YL
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Molecular nutrition & food research 2019 Dec;63(24):e1900418
Paeonol prevents IL-1β-induced inflammatory response and degradation of type II collagen in human primary chondrocytes.
Wang Q, Xu X, Kang Z, Zhang Z, Li Y
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2139-2145
Artificial cells, nanomedicine, and biotechnology 2019 Dec;47(1):2139-2145
Study of Bone Regeneration and Osteointegration Effect of a Novel Selective Laser-Melted Titanium-Tantalum-Niobium-Zirconium Alloy Scaffold.
Guo Y, Wu J, Xie K, Tan J, Yang Y, Zhao S, Wang L, Jiang W, Hao Y
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
ACS biomaterials science & engineering 2019 Dec 9;5(12):6463-6473
Exogenous H2S mitigates myocardial fibrosis in diabetic rats through suppression of the canonical Wnt pathway.
Yang R, Jia Q, Ma SF, Wang Y, Mehmood S, Chen Y
International journal of molecular medicine 2019 Aug;44(2):549-558
International journal of molecular medicine 2019 Aug;44(2):549-558
High cholesterol inhibits tendon-related gene expressions in tendon-derived stem cells through reactive oxygen species-activated nuclear factor-κB signaling.
Li K, Deng G, Deng Y, Chen S, Wu H, Cheng C, Zhang X, Yu B, Zhang K
Journal of cellular physiology 2019 Aug;234(10):18017-18028
Journal of cellular physiology 2019 Aug;234(10):18017-18028
LncRNA PCFL promotes cardiac fibrosis via miR-378/GRB2 pathway following myocardial infarction.
Sun F, Zhuang Y, Zhu H, Wu H, Li D, Zhan L, Yang W, Yuan Y, Xie Y, Yang S, Luo S, Jiang W, Zhang J, Pan Z, Lu Y
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
Journal of molecular and cellular cardiology 2019 Aug;133:188-198
IMM-H007 improves heart function via reducing cardiac fibrosis.
Ge W, Zhang W, Gao R, Li B, Zhu H, Wang J
European journal of pharmacology 2019 Aug 15;857:172442
European journal of pharmacology 2019 Aug 15;857:172442
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Liraglutide prevents β-cell apoptosis via inactivation of NOX2 and its related signaling pathway.
Ding M, Fang QH, Cui YT, Shen QL, Liu Q, Wang PH, Yu DM, Li CJ
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Journal of diabetes and its complications 2019 Apr;33(4):267-277
Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.
Zhao J, Meng M, Zhang J, Li L, Zhu X, Zhang L, Wang C, Gao M
Molecular medicine reports 2019 Apr;19(4):3168-3178
Molecular medicine reports 2019 Apr;19(4):3168-3178
The inhibitory effects of COL1A2 on colorectal cancer cell proliferation, migration, and invasion.
Yu Y, Liu D, Liu Z, Li S, Ge Y, Sun W, Liu B
Journal of Cancer 2018;9(16):2953-2962
Journal of Cancer 2018;9(16):2953-2962
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, Wang C, Zhou J, Gao D, Hu Y, Tian X, Yao J
Frontiers in pharmacology 2018;9:1277
Frontiers in pharmacology 2018;9:1277
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.
Liang H, Pan Z, Zhao X, Liu L, Sun J, Su X, Xu C, Zhou Y, Zhao D, Xu B, Li X, Yang B, Lu Y, Shan H
Theranostics 2018;8(4):1180-1194
Theranostics 2018;8(4):1180-1194
Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation.
Zhou B, Ling L, Zhang F, Liu TY, Zhou H, Qi XH, Chen Q, Li YH, Kang YM, Zhu GQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):227-236
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(1):227-236
Downregulation of S100A4 Alleviates Cardiac Fibrosis via Wnt/β -Catenin Pathway in Mice.
Qian L, Hong J, Zhang Y, Zhu M, Wang X, Zhang Y, Chu M, Yao J, Xu D
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2551-2560
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(6):2551-2560
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
International journal of chronic obstructive pulmonary disease 2018;13:473-486
International journal of chronic obstructive pulmonary disease 2018;13:473-486
Wenyang Huazhuo Tongluo formula inhibits fibrosis via suppressing Wnt/β-catenin signaling pathway in a Bleomycin-induced systemic sclerosis mouse model.
Wang Q, Zang W, Han L, Yang L, Ye S, Ouyang J, Zhang C, Bi Y, Zhang C, Bian H
Chinese medicine 2018;13:17
Chinese medicine 2018;13:17
TGF-β1/Smad3 signaling promotes collagen synthesis in pulmonary artery smooth muscle by down-regulating miR-29b.
Wang T, Li Y, Chen J, Xie L, Xiao T
International journal of clinical and experimental pathology 2018;11(12):5592-5601
International journal of clinical and experimental pathology 2018;11(12):5592-5601
A novel bioscaffold with naturally-occurring extracellular matrix promotes hepatocyte survival and vessel patency in mouse models of heterologous transplantation.
Yang W, Chen Q, Xia R, Zhang Y, Shuai L, Lai J, You X, Jiang Y, Bie P, Zhang L, Zhang H, Bai L
Biomaterials 2018 Sep;177:52-66
Biomaterials 2018 Sep;177:52-66
Interleukin-17 enhances cardiac ventricular remodeling via activating MAPK pathway in ischemic heart failure.
Chang SL, Hsiao YW, Tsai YN, Lin SF, Liu SH, Lin YJ, Lo LW, Chung FP, Chao TF, Hu YF, Tuan TC, Liao JN, Hsieh YC, Wu TJ, Higa S, Chen SA
Journal of molecular and cellular cardiology 2018 Sep;122:69-79
Journal of molecular and cellular cardiology 2018 Sep;122:69-79
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
Wu J, Liu J, Ding Y, Zhu M, Lu K, Zhou J, Xie X, Xu Y, Shen X, Chen Y, Shao X, Zhu C
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Zhao X, Sun J, Chen Y, Su W, Shan H, Li Y, Wang Y, Zheng N, Shan H, Liang H
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
Zhang C, Liu XQ, Sun HN, Meng XM, Bao YW, Zhang HP, Pan FM, Zhang C
International immunopharmacology 2018 Oct;63:183-190
International immunopharmacology 2018 Oct;63:183-190
lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a.
Li X, Yu T, Shan H, Jiang H, Sun J, Zhao X, Su W, Yang L, Shan H, Liang H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2018 Oct;32(10):5285-5297
Antifibrotic Agent Pirfenidone Protects against Development of Radiation-Induced Pulmonary Fibrosis in a Murine Model.
Qin W, Liu B, Yi M, Li L, Tang Y, Wu B, Yuan X
Radiation research 2018 Oct;190(4):396-403
Radiation research 2018 Oct;190(4):396-403
Salvianolic Acid B-Alleviated Angiotensin II Induces Cardiac Fibrosis by Suppressing NF-κB Pathway In Vitro.
Wang C, Luo H, Xu Y, Tao L, Chang C, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Medical science monitor : international medical journal of experimental and clinical research 2018 Oct 26;24:7654-7664
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway.
Zhao X, Qu G, Song C, Li R, Liu W, Lv C, Song X, Zhang J, Li M
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Toxicology and applied pharmacology 2018 Oct 1;356:15-24
Emission of sulfur dioxide from polyurethane foam and respiratory health effects.
Xu W, Li J, Zhang W, Wang Z, Wu J, Ge X, Wu J, Cao Y, Xie Y, Ying D, Wang Y, Wang L, Qiao Z, Jia J
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt A):90-97
Environmental pollution (Barking, Essex : 1987) 2018 Nov;242(Pt A):90-97
Thrombin induces protease-activated receptor 1 signaling and activation of human atrial fibroblasts and dabigatran prevents these effects.
Altieri P, Bertolotto M, Fabbi P, Sportelli E, Balbi M, Santini F, Brunelli C, Canepa M, Montecucco F, Ameri P
International journal of cardiology 2018 Nov 15;271:219-227
International journal of cardiology 2018 Nov 15;271:219-227
Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro.
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z
Redox biology 2018 May;15:62-73
Redox biology 2018 May;15:62-73
Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration.
Luo X, Wang D, Zhu X, Wang G, You Y, Ning Z, Li Y, Jin S, Huang Y, Hu Y, Chen T, Meng Y, Li X
Cell death & disease 2018 May 1;9(5):576
Cell death & disease 2018 May 1;9(5):576
Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1.
Liu X, Zhang Y, Shi M, Wang Y, Zhang F, Yan R, Liu L, Xiao Y, Guo B
Biochemical and biophysical research communications 2018 Mar 18;497(4):1110-1116
Biochemical and biophysical research communications 2018 Mar 18;497(4):1110-1116
Interleukin-6 Promotes Proliferation but Inhibits Tenogenic Differentiation via the Janus Kinase/Signal Transducers and Activators of Transcription 3 (JAK/STAT3) Pathway in Tendon-Derived Stem Cells.
Chen S, Deng G, Li K, Zheng H, Wang G, Yu B, Zhang K
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Medical science monitor : international medical journal of experimental and clinical research 2018 Mar 16;24:1567-1573
Effects of nicotine on the metabolism and gene expression profile of Sprague‑Dawley rat primary osteoblasts.
Liang D, Wang KJ, Tang ZQ, Liu RH, Zeng F, Cheng MY, Lian QS, Wu HK
Molecular medicine reports 2018 Jun;17(6):8269-8281
Molecular medicine reports 2018 Jun;17(6):8269-8281
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, Chang Q, Duan Z
BMC gastroenterology 2018 Jul 11;18(1):112
BMC gastroenterology 2018 Jul 11;18(1):112
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Aucubin Protects against TGFβ1-Induced Cardiac Fibroblasts Activation by Mediating the AMPKα/mTOR Signaling Pathway.
Xiao Y, Chang W, Wu QQ, Jiang XH, Duan MX, Jin YG, Tang QZ
Planta medica 2018 Jan;84(2):91-99
Planta medica 2018 Jan;84(2):91-99
COL1A2 is a Novel Biomarker to Improve Clinical Prediction in Human Gastric Cancer: Integrating Bioinformatics and Meta-Analysis.
Rong L, Huang W, Tian S, Chi X, Zhao P, Liu F
Pathology oncology research : POR 2018 Jan;24(1):129-134
Pathology oncology research : POR 2018 Jan;24(1):129-134
Losartan loaded liposomes improve the antitumor efficacy of liposomal paclitaxel modified with pH sensitive peptides by inhibition of collagen in breast cancer.
Xia T, He Q, Shi K, Wang Y, Yu Q, Zhang L, Zhang Q, Gao H, Ma L, Liu J
Pharmaceutical development and technology 2018 Jan;23(1):13-21
Pharmaceutical development and technology 2018 Jan;23(1):13-21
Regulation of pancreatic stellate cell activation by Notch3.
Song H, Zhang Y
BMC cancer 2018 Jan 5;18(1):36
BMC cancer 2018 Jan 5;18(1):36
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
Zhang X, Ma ZG, Yuan YP, Xu SC, Wei WY, Song P, Kong CY, Deng W, Tang QZ
Cell death & disease 2018 Jan 24;9(2):102
Cell death & disease 2018 Jan 24;9(2):102
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984
Crosslinking Enzyme Lysyl Oxidase Modulates Scleral Remodeling in Form-Deprivation Myopia.
Yuan Y, Li M, Chen Q, Me R, Yu Y, Gu Q, Shi G, Ke B
Current eye research 2018 Feb;43(2):200-207
Current eye research 2018 Feb;43(2):200-207
Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas After Chronic Alcohol Exposure.
Li H, Xiu M, Wang S, Brigstock DR, Sun L, Qu L, Gao R
Alcoholism, clinical and experimental research 2018 Feb;42(2):306-314
Alcoholism, clinical and experimental research 2018 Feb;42(2):306-314
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
Wu J, Xing C, Zhang L, Mao H, Chen X, Liang M, Wang F, Ren H, Cui H, Jiang A, Wang Z, Zou M, Ji Y
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, Li Y, Xu Y, Zhong Z, Shen J, Chu D
Cellular & molecular immunology 2018 Feb;15(2):120-134
Cellular & molecular immunology 2018 Feb;15(2):120-134
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Li Z, Ding Q, Ling LP, Wu Y, Meng DX, Li X, Zhang CQ
World journal of gastroenterology 2018 Feb 21;24(7):819-832
World journal of gastroenterology 2018 Feb 21;24(7):819-832
Baicalin inhibits pressure overload-induced cardiac fibrosis through regulating AMPK/TGF-β/Smads signaling pathway.
Xiao Y, Ye J, Zhou Y, Huang J, Liu X, Huang B, Zhu L, Wu B, Zhang G, Cai Y
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Archives of biochemistry and biophysics 2018 Feb 15;640:37-46
Interleukin‑10 promotes proliferation and migration, and inhibits tendon differentiation via the JAK/Stat3 pathway in tendon‑derived stem cells in vitro.
Deng G, Li K, Chen S, Chen P, Zheng H, Yu B, Zhang K
Molecular medicine reports 2018 Dec;18(6):5044-5052
Molecular medicine reports 2018 Dec;18(6):5044-5052
CAPE-pNO(2) attenuates diabetic cardiomyopathy through the NOX4/NF-κB pathway in STZ-induced diabetic mice.
Fan L, Xiao Q, Zhang L, Wang X, Huang Q, Li S, Zhao X, Li Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Dec;108:1640-1650
Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem.
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, Wang Y, Zhao R, Anderson GJ, Zhao Y, Nie G
Nature communications 2018 Aug 23;9(1):3390
Nature communications 2018 Aug 23;9(1):3390
Effect of Polyhydroxybutyrate/Chitosan/Bioglass nanofiber scaffold on proliferation and differentiation of stem cells from human exfoliated deciduous teeth into odontoblast-like cells.
Khoroushi M, Foroughi MR, Karbasi S, Hashemibeni B, Khademi AA
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:128-139
Materials science & engineering. C, Materials for biological applications 2018 Aug 1;89:128-139
Hydrogen sulfide ameliorates aging-associated changes in the kidney.
Lee HJ, Feliers D, Barnes JL, Oh S, Choudhury GG, Diaz V, Galvan V, Strong R, Nelson J, Salmon A, Kevil CG, Kasinath BS
GeroScience 2018 Apr;40(2):163-176
GeroScience 2018 Apr;40(2):163-176
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Sun L, Xiu M, Wang S, Brigstock DR, Li H, Qu L, Gao R
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Zhao W, Yang A, Chen W, Wang P, Liu T, Cong M, Xu A, Yan X, Jia J, You H
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Zhao X, Sun J, Su W, Shan H, Zhang B, Wang Y, Shabanova A, Shan H, Liang H
International journal of molecular sciences 2018 Apr 9;19(4)
International journal of molecular sciences 2018 Apr 9;19(4)
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
Pei Z, Hu J, Bai Q, Liu B, Cheng D, Liu H, Na R, Yu Q
RSC advances 2018 Apr 17;8(26):14633-14639
RSC advances 2018 Apr 17;8(26):14633-14639
Novel decellularized liver matrix-alginate hybrid gel beads for the 3D culture of hepatocellular carcinoma cells.
Sun D, Liu Y, Wang H, Deng F, Zhang Y, Zhao S, Ma X, Wu H, Sun G
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
International journal of biological macromolecules 2018 Apr 1;109:1154-1163
The Protective Effect of Cordycepin On Alcohol-Induced Osteonecrosis of the Femoral Head.
Chen YX, Zhu DY, Xu ZL, Yin JH, Yu XW, Mei J, Gao YS, Zhang CQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2391-2403
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(6):2391-2403
Far-infrared suppresses skin photoaging in ultraviolet B-exposed fibroblasts and hairless mice.
Chiu HW, Chen CH, Chen YJ, Hsu YH
PloS one 2017;12(3):e0174042
PloS one 2017;12(3):e0174042
Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.
Luo H, Liu B, Zhao L, He J, Li T, Zha L, Li X, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
Journal of the American Society of Hypertension : JASH 2017 Oct;11(10):673-683.e3
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Cai Y, Ma W, Xiao Y, Wu B, Li X, Liu F, Qiu J, Zhang G
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
MicroRNA-133 overexpression promotes the therapeutic efficacy of mesenchymal stem cells on acute myocardial infarction.
Chen Y, Zhao Y, Chen W, Xie L, Zhao ZA, Yang J, Chen Y, Lei W, Shen Z
Stem cell research & therapy 2017 Nov 25;8(1):268
Stem cell research & therapy 2017 Nov 25;8(1):268
The protective effect of PFTα on alcohol-induced osteonecrosis of the femoral head.
Chen YX, Zhu DY, Yin JH, Yin WJ, Zhang YL, Ding H, Yu XW, Mei J, Gao YS, Zhang CQ
Oncotarget 2017 Nov 21;8(59):100691-100707
Oncotarget 2017 Nov 21;8(59):100691-100707
The effects of artocarpin on wound healing: in vitro and in vivo studies.
Yeh CJ, Chen CC, Leu YL, Lin MW, Chiu MM, Wang SH
Scientific reports 2017 Nov 15;7(1):15599
Scientific reports 2017 Nov 15;7(1):15599
Bcl-3 is a novel biomarker of renal fibrosis in chronic kidney disease.
Chen R, Wang L, Liu S, Chen X, Hu Y, Liu H, Zhang H, Jiang Y, Wang Q, Ye D, Li L, Liu D, Pan X, Wei L, Li X, Zhang X
Oncotarget 2017 Nov 14;8(57):97206-97216
Oncotarget 2017 Nov 14;8(57):97206-97216
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling.
Feng GS, Zhu CG, Li ZM, Wang PX, Huang Y, Liu M, He P, Lou LL, Chen SR, Liu PQ
Acta pharmacologica Sinica 2017 May;38(5):638-650
Acta pharmacologica Sinica 2017 May;38(5):638-650
MgAl layered double hydroxide/chitosan porous scaffolds loaded with PFTα to promote bone regeneration.
Chen YX, Zhu R, Ke QF, Gao YS, Zhang CQ, Guo YP
Nanoscale 2017 May 25;9(20):6765-6776
Nanoscale 2017 May 25;9(20):6765-6776
Cadherin-11 modulates cell morphology and collagen synthesis in periodontal ligament cells under mechanical stress.
Feng L, Zhang Y, Kou X, Yang R, Liu D, Wang X, Song Y, Cao H, He D, Gan Y, Zhou Y
The Angle orthodontist 2017 Mar;87(2):193-199
The Angle orthodontist 2017 Mar;87(2):193-199
Activation of E-prostanoid 3 receptor in macrophages facilitates cardiac healing after myocardial infarction.
Tang J, Shen Y, Chen G, Wan Q, Wang K, Zhang J, Qin J, Liu G, Zuo S, Tao B, Yu Y, Wang J, Lazarus M, Yu Y
Nature communications 2017 Mar 3;8:14656
Nature communications 2017 Mar 3;8:14656
Evodiamine attenuates TGF-β1-induced fibroblast activation and endothelial to mesenchymal transition.
Wu QQ, Xiao Y, Jiang XH, Yuan Y, Yang Z, Chang W, Bian ZY, Tang QZ
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Molecular and cellular biochemistry 2017 Jun;430(1-2):81-90
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Tu J, Li W, Zhang Y, Wu X, Song Y, Kang L, Liu W, Wang K, Li S, Hua W, Yang C
Inflammation 2017 Jun;40(3):725-734
Inflammation 2017 Jun;40(3):725-734
Development of a new biodegradable operative clip made of a magnesium alloy: Evaluation of its safety and tolerability for canine cholecystectomy.
Yoshida T, Fukumoto T, Urade T, Kido M, Toyama H, Asari S, Ajiki T, Ikeo N, Mukai T, Ku Y
Surgery 2017 Jun;161(6):1553-1560
Surgery 2017 Jun;161(6):1553-1560
SC79-loaded ZSM-5/chitosan porous scaffolds with enhanced stem cell osteogenic differentiation and bone regeneration.
Zhu R, Chen YX, Ke QF, Gao YS, Guo YP
Journal of materials chemistry. B 2017 Jul 7;5(25):5009-5018
Journal of materials chemistry. B 2017 Jul 7;5(25):5009-5018
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat.
Luo L, Xi C, Xu T, Zhang G, Qun E, Zhang W
European journal of pharmacology 2017 Jul 15;807:109-116
European journal of pharmacology 2017 Jul 15;807:109-116
Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver.
Luo L, Xu T, Wang P, Mao L, Xi C, Huang J, Zhang W
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2017 Feb;69(2):73-81
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Cowling RT, Park JI, Sotimehin AE, Greenberg BH
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Journal of molecular and cellular cardiology 2017 Dec;113:1-8
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
Relaxin alleviates TGFβ1-induced cardiac fibrosis via inhibition of Stat3-dependent autophagy.
Yuan Y, Zhang Y, Han X, Li Y, Zhao X, Sheng L, Li Y
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Biochemical and biophysical research communications 2017 Dec 2;493(4):1601-1607
Hepatitis B virus X protein promotes the development of liver fibrosis and hepatoma through downregulation of miR-30e targeting P4HA2 mRNA.
Feng GX, Li J, Yang Z, Zhang SQ, Liu YX, Zhang WY, Ye LH, Zhang XD
Oncogene 2017 Dec 14;36(50):6895-6905
Oncogene 2017 Dec 14;36(50):6895-6905
Electrospun Decellularized Lung Matrix Scaffold for Airway Smooth Muscle Culture.
Young BM, Shankar K, Allen BP, Pouliot RA, Schneck MB, Mikhaiel NS, Heise RL
ACS biomaterials science & engineering 2017 Dec 11;3(12):3480-3492
ACS biomaterials science & engineering 2017 Dec 11;3(12):3480-3492
Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Wu L, Zhang Q, Mo W, Feng J, Li S, Li J, Liu T, Xu S, Wang W, Lu X, Yu Q, Chen K, Xia Y, Lu J, Xu L, Zhou Y, Fan X, Guo C
Scientific reports 2017 Aug 24;7(1):9289
Scientific reports 2017 Aug 24;7(1):9289
Autophagic Degradation of Collagen 1A1 by Cortisol in Human Amnion Fibroblasts.
Mi Y, Wang W, Zhang C, Liu C, Lu J, Li W, Zuo R, Myatt L, Sun K
Endocrinology 2017 Apr 1;158(4):1005-1014
Endocrinology 2017 Apr 1;158(4):1005-1014
Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state.
Sun A, Wang Y, Liu J, Yu X, Sun Y, Yang F, Dong S, Wu J, Zhao Y, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:36
Cell & bioscience 2016;6:36
Sonodynamic Therapy Inhibits Fibrogenesis in Rat Cardiac Fibroblasts Induced by TGF-β1.
Guo Y, Dong Z, Shi Y, Wang W, Wang L, Sun J, Sun X, Tian Z, Yao J, Li Z, Cheng J, Tian Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(3-4):579-588
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Zhang J, An SJ, Fu JQ, Liu P, Shao TM, Li M, Li X, Jiao Z, Chai XQ
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;40(1-2):347-360
Expression of Wnt/β-Catenin Signaling Pathway and Its Regulatory Role in Type I Collagen with TGF-β1 in Scleral Fibroblasts from an Experimentally Induced Myopia Guinea Pig Model.
Li M, Yuan Y, Chen Q, Me R, Gu Q, Yu Y, Sheng M, Ke B
Journal of ophthalmology 2016;2016:5126560
Journal of ophthalmology 2016;2016:5126560
Tetramethylpyrazine Attenuates Transdifferentiation of TGF-β2-Treated Human Tenon's Fibroblasts.
Cai X, Yang Y, Chen P, Ye Y, Liu X, Wu K, Yu M
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Investigative ophthalmology & visual science 2016 Sep 1;57(11):4740-8
Suppression for lung metastasis by depletion of collagen I and lysyl oxidase via losartan assisted with paclitaxel-loaded pH-sensitive liposomes in breast cancer.
Zhang L, Wang Y, Xia T, Yu Q, Zhang Q, Yang Y, Cun X, Lu L, Gao H, Zhang Z, He Q
Drug delivery 2016 Oct;23(8):2970-2979
Drug delivery 2016 Oct;23(8):2970-2979
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Tang H, Fan D, Lei CT, Ye C, Gao P, Chen S, Meng XF, Su H, Zhang C
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Store-Operated Ca(2+) Entry (SOCE) contributes to angiotensin II-induced cardiac fibrosis in cardiac fibroblasts.
Zhang B, Jiang J, Yue Z, Liu S, Ma Y, Yu N, Gao Y, Sun S, Chen S, Liu P
Journal of pharmacological sciences 2016 Nov;132(3):171-180
Journal of pharmacological sciences 2016 Nov;132(3):171-180
PPAR-γ is involved in the protective effect of 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside against cardiac fibrosis in pressure-overloaded rats.
Peng Y, Zeng Y, Xu J, Huang XL, Zhang W, Xu XL
European journal of pharmacology 2016 Nov 15;791:105-114
European journal of pharmacology 2016 Nov 15;791:105-114
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Zhang Y, Wang JH, Zhang YY, Wang YZ, Wang J, Zhao Y, Jin XX, Xue GL, Li PH, Sun YL, Huang QH, Song XT, Zhang ZR, Gao X, Yang BF, Du ZM, Pan ZW
Scientific reports 2016 Mar 14;6:23010
Scientific reports 2016 Mar 14;6:23010
miR-26a suppresses EMT by disrupting the Lin28B/let-7d axis: potential cross-talks among miRNAs in IPF.
Liang H, Liu S, Chen Y, Bai X, Liu L, Dong Y, Hu M, Su X, Chen Y, Huangfu L, Li X, Gu Y, Shan H
Journal of molecular medicine (Berlin, Germany) 2016 Jun;94(6):655-65
Journal of molecular medicine (Berlin, Germany) 2016 Jun;94(6):655-65
Increased expression of Talin1 in the eutopic and ectopic endometria of women with adenomyosis.
Jiang J, Sun A, Wang Y, Deng Y
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2016 Jun;32(6):469-72
A dual strategy to improve the penetration and treatment of breast cancer by combining shrinking nanoparticles with collagen depletion by losartan.
Cun X, Ruan S, Chen J, Zhang L, Li J, He Q, Gao H
Acta biomaterialia 2016 Feb;31:186-196
Acta biomaterialia 2016 Feb;31:186-196
An Ultra-thin Amniotic Membrane as Carrier in Corneal Epithelium Tissue-Engineering.
Zhang L, Zou D, Li S, Wang J, Qu Y, Ou S, Jia C, Li J, He H, Liu T, Yang J, Chen Y, Liu Z, Li W
Scientific reports 2016 Feb 15;6:21021
Scientific reports 2016 Feb 15;6:21021
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Protective effects of triptolide on TLR4 mediated autoimmune and inflammatory response induced myocardial fibrosis in diabetic cardiomyopathy.
Guo X, Xue M, Li CJ, Yang W, Wang SS, Ma ZJ, Zhang XN, Wang XY, Zhao R, Chang BC, Chen LM
Journal of ethnopharmacology 2016 Dec 4;193:333-344
Journal of ethnopharmacology 2016 Dec 4;193:333-344
A fundamental study on the dynamics of multiple biomarkers in mouse excisional wounds for wound age estimation.
Wang LL, Zhao R, Liu CS, Liu M, Li SS, Li JY, Jiang SK, Zhang M, Tian ZL, Wang M, Zhang MZ, Guan DW
Journal of forensic and legal medicine 2016 Apr;39:138-46
Journal of forensic and legal medicine 2016 Apr;39:138-46
MALAT1 functions as a competing endogenous RNA to mediate Rac1 expression by sequestering miR-101b in liver fibrosis.
Yu F, Lu Z, Cai J, Huang K, Chen B, Li G, Dong P, Zheng J
Cell cycle (Georgetown, Tex.) 2015;14(24):3885-96
Cell cycle (Georgetown, Tex.) 2015;14(24):3885-96
Ursolic acid attenuates diabetic mesangial cell injury through the up-regulation of autophagy via miRNA-21/PTEN/Akt/mTOR suppression.
Lu X, Fan Q, Xu L, Li L, Yue Y, Xu Y, Su Y, Zhang D, Wang L
PloS one 2015;10(2):e0117400
PloS one 2015;10(2):e0117400
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
High Tumor Penetration of Paclitaxel Loaded pH Sensitive Cleavable Liposomes by Depletion of Tumor Collagen I in Breast Cancer.
Zhang L, Wang Y, Yang Y, Liu Y, Ruan S, Zhang Q, Tai X, Chen J, Xia T, Qiu Y, Gao H, He Q
ACS applied materials & interfaces 2015 May 13;7(18):9691-701
ACS applied materials & interfaces 2015 May 13;7(18):9691-701
Establishing principles of macromolecular crowding for in vitro fibrosis research of the vocal fold lamina propria.
Graupp M, Gruber HJ, Weiss G, Kiesler K, Bachna-Rotter S, Friedrich G, Gugatschka M
The Laryngoscope 2015 Jun;125(6):E203-9
The Laryngoscope 2015 Jun;125(6):E203-9
High doses of (-)-epigallocatechin-3-gallate from green tea induces cardiac fibrosis in mice.
Cai Y, He SQ, Hong HQ, Cai YP, Zhao L, Zhang M
Biotechnology letters 2015 Dec;37(12):2371-7
Biotechnology letters 2015 Dec;37(12):2371-7
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Ahram DF, Cook AC, Kecova H, Grozdanic SD, Kuehn MH
Molecular vision 2014;20:497-510
Molecular vision 2014;20:497-510
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Ma J, Zhou D, Fan M, Wang H, Huang C, Zhang Z, Wu Y, Li W, Chen Y, Liu Z
Investigative ophthalmology & visual science 2014 Sep 4;55(10):6691-703
Investigative ophthalmology & visual science 2014 Sep 4;55(10):6691-703
Surface chemistry modulates osteoblasts sensitivity to low fluid shear stress.
Xing J, Li Y, Lin M, Wang J, Wu J, Ma Y, Wang Y, Yang L, Luo Y
Journal of biomedical materials research. Part A 2014 Nov;102(11):4151-60
Journal of biomedical materials research. Part A 2014 Nov;102(11):4151-60
Mechano growth factor E peptide regulates migration and differentiation of bone marrow mesenchymal stem cells.
Cui H, Yi Q, Feng J, Yang L, Tang L
Journal of molecular endocrinology 2014 Apr;52(2):111-20
Journal of molecular endocrinology 2014 Apr;52(2):111-20
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Xu D, Yang W, Hu Y, Luo Z, Li J, Hou Y, Liu Y, Cai K
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Inhibition of farnesyl pyrophosphate synthase attenuates angiotensin II-induced cardiac hypertrophy and fibrosis in vivo.
Yang J, Zhu HH, Chen GP, Ye Y, Zhao CZ, Mou Y, Hu SJ
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
The international journal of biochemistry & cell biology 2013 Mar;45(3):657-66
The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism.
Liu T, Wang P, Cong M, Xu Y, Jia J, You H
Bioscience reports 2013 Jun 5;33(3)
Bioscience reports 2013 Jun 5;33(3)
Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model.
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, Sun X, Mao L, Xiang H
Journal of natural medicines 2013 Jan;67(1):86-97
Journal of natural medicines 2013 Jan;67(1):86-97
Molecular events in matrix protein metabolism in the aging kidney.
Sataranatarajan K, Feliers D, Mariappan MM, Lee HJ, Lee MJ, Day RT, Yalamanchili HB, Choudhury GG, Barnes JL, Van Remmen H, Richardson A, Kasinath BS
Aging cell 2012 Dec;11(6):1065-73
Aging cell 2012 Dec;11(6):1065-73
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 14695-1-AP(COL1A2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin cancer using 14695-1-AP(COL1A2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Collagen Type I antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Collagen Type I. This antibody recognizes human, mouse antigen. The Collagen Type I antibody has been validated for the following applications: ELISA, WB, IHC analysis.
