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- Antibody Data
- Antigen structure
- References [216]
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- Product number
- 66761-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Collagen Type I antibody
- Antibody type
- Monoclonal
- Description
- Collagen Type I antibody (Cat. #66761-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, pig, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3D5E8
- Vial size
- 20ul, 150ul
Submitted references Buyang Huanwu Decoction Alleviates Chronic Intermittent Hypoxia-Induced Myocardial Inflammation and Fibrosis via the NF-κB/LOX Signaling Pathway.
Stem cell therapy targets THBS1 to reverse endometrial fibrosis.
Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
Inhibiting cGAS-STING to Preserve Mitochondrial-Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age-Related Tendinopathy.
Decoding the spatiotemporal development of the blood-brain barrier in human cortex.
Study on the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula by inhibiting M2 macrophage polarization and regulating TGF - β/SMAD signaling pathway.
N-acetylglucosamine ameliorates the transition from acute kidney injury to chronic kidney disease by reducing the accumulation of lipid droplets.
Advanced Hydrogel/Electrospun Nanofiber Composite Scaffold With Sequential Bioactive Factor Release for Rotator Cuff Repair.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Small-molecule LF3 alleviates angiotensin II-induced cardiac dysfunction via attenuating cardiac fibrosis.
SLIT3/ROBO1 axis contributes to angiogenic-osteogenic coupling in endothelial progenitor cells and peripheral blood mesenchymal stem cells.
Inhalable lipid nanoparticles for macrophage-specific STING gene editing to ameliorate pulmonary fibrosis.
Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
Mechanism of macrophage mitochondrial transfer in CBNPs induced EndMT of pulmonary microvascular endothelial cells.
Hyaluronic acid-based reactive oxygen species responsive nanocomposite hydrogel for sequential drug delivery and effective prevention of postoperative abdominal adhesions.
FOSL1 mediates collagen synthesis and myofibroblast transformation in aortic fibroblasts under Ang II-induced aortic dissection conditions.
Biodegradable Mg(2+)-releasing piezoelectric scaffold for segmental bone defect repair.
Lathyrane diterpenoids with anti-renal fibrotic activity from the aboveground parts of Euphorbia wallichii.
FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome.
Early Intervention of Subchondral Bone Resorption Mitigates Cartilage Degeneration in TMJOA.
Gas diffusion-mediated single-sided in situ gradient mineralized silk fibroin membrane for enhanced guided bone regeneration.
Transdermal delivery of salvianolic acid B using thermosensitive hydrogel for the treatment of skin photoaging.
Dual-PPARα/δ agonist H11 alleviates tendinopathy via modulating the Nrf2/HO-1/GPX4 pathway.
SLC22A17 affects the development of urethral stricture by promoting ferroptosis and inhibiting the activation of fibroblasts.
From rosemary and coffee to bioactive nanovesicles: exploring new frontiers in food functional ingredients.
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
An Immune-privileged niche mediates immunotherapy resistance in esophageal carcinoma.
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Biomimetic Multilayered Gas-Foaming Scaffold with Sustained bFGF Delivery for Annulus Fibrosus Regeneration.
DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.
Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF-β1.
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Treadmill running modulates infrapatellar fat pad remodeling in osteoarthritic rats in an intensity-dependent manner.
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Integrated network pharmacology and bioinformatics analysis reveals MME as key target of Notoginsenoside R1 in diabetic nephropathy.
BMP2@PDA-LDH functionalized coating on ZK60 magnesium alloy: Enhanced corrosion resistance and promoted bone defect regeneration.
LCZ696 (Sac/Val) protects against high-fat diet-induced kidney injury in mice by targeting ROCK2 to suppress ROCK2/NF-κB signaling.
VEGF-sustained regulation and hydrogel-activated graded porous titanium scaffold for functional regeneration of the tendon-bone interface.
CCT7 Regulates TRAF6-Mediated Autophagy to Promote Posttraumatic Joint Contracture.
Gamma delta T cells promote intestinal fibrosis via an interleukin-17A-induced transforming growth factor-beta signaling pathway in fibroblasts.
An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing.
Multifunctional 3D-Printed Titanium Alloy Composite-Coated Scaffold for Modulating the Immune Microenvironment and Promoting Osteogenesis.
Targeting Tumor Microenvironment-Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer.
Fibrosis suppressive effect and mechanism of CaSR positive allosteric modulators/p-dioxanone copolymers.
Salidroside ameliorates skin aging in male mice by promoting collagen regeneration via modulation of FOS and MMP9.
Store-operated Ca(2+) entry contributes to the ASM phenotype transition in asthma.
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics.
Curculigoside alleviates ferroptosis in renal interstitial fibrosis by regulating the Nrf2/HO-1 signaling pathway.
Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway.
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
Ivermectin attenuates Schistosoma japonicum-induced liver fibrosis and is associated with downregulation of YAP signaling.
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Vericiguat as a novel PPARα ligand alleviates pressure-overload-induced heart failure.
High-Yield Extruded Nanovesicles From Adipose Stem Cells Promote High-Quality Healing of Diabetic Wound Through WNT/β-Catenin Pathway Activation.
ADSC-enriched adipose extract alleviates cartilage fibrosis in temporomandibular joint osteoarthritis by inhibiting chondrocyte senescence.
Anemoside B4 improves cardiac function after myocardial infarction by regulating HTR2A/ERK pathway.
SIRT5 induces glomerular sclerosis in diabetic nephropathy through p53.
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
An Ile to Met polymorphism in ADCY9 promotes airway obstruction and remodeling in asthma.
Blocking IL-6 down-regulates PD-L1 expression and mitigates pulmonary fibrosis by inhibiting the STAT3 signaling pathway.
Isobavachin alleviates hyperuricemia-induced bone loss by GPR35-NLRP3 signal.
Single-cell RNA sequencing revealed the association between proximal tubular epithelial cells and renal interstitial cells in chronic kidney disease progression.
JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7.
Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cells.
Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation.
Transcriptional Study of Radiofrequency Device Using Experimental Mouse Model.
Dual-step photo-induced self-assembled hydrogel for endogenous oral mucosal wound healing.
A Highly Bioactive Organic-Inorganic Nanoparticle for Activating Wnt10b Mediated Osteogenesis by Specifically Anchor CCN3 Protein.
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA(+) macrophages contribute to atherosclerotic plaque formation.
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
Therapeutic inhibition of PHF21B attenuates pathological cardiac hypertrophy by inhibiting the BMP4/GSK3β/β-catenin axis.
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
Sequential SDF-1/CGRP-releasing smart composite hydrogel promotes osteoporotic fracture healing by targeting sensory nerve-regulated bone remodeling.
Cerebral [(18)F]AIF-FAPI-42-Based PET Imaging of Fibroblast Activation Protein for Non-invasive Quantification of Fibrosis After Ischemic Stroke.
Diabetic wound healing breakthrough: theaflavin-3, 3'-digallate nanoparticles@hydrogel activates the TGF-β1/SMAD3 pathway.
Micro/Nanofibrous Polycaprolactone Scaffolds Loaded with Gentamicin for Improved Antimicrobial Activities under Seawater Immersion.
Mast cell tryptase-PAR2 axis promotes ovarian fibrosis through RNF152-mediated stabilization of Bcl-xL.
TIMP1 regulation of cardiac fibroblast proliferation via the TGF-β/Smad pathway in an in vitro model of atrial fibrillation.
Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling.
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
Irisin attenuates liver fibrosis by regulating energy metabolism and HMGB1/β-catenin signaling in hepatic stellate cells.
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway.
FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation.
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
H3K36me3 modification by SETD2 is essential for Col11a2 and Sema3e transcription to maintain dentinogenesis in mice.
Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration.
Proteomics analysis revealed the therapeutic role of adipose-derived mesenchymal stem cells on radiation-induced colorectal fibrosis in rats.
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Bie Jia Jian pill ameliorates BDL-induced cholestatic hepatic fibrosis in rats by regulating intestinal microbial composition and TMAO-mediated PI3K/AKT signaling pathway.
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Sunscreen Formula of FeO(OH)·H(2)O/TiO(2) With Spectral Selectivity to Enhance Collagen Biosynthesis via Fibroblast Test.
Dedicator of cytokinesis protein 2 activates the epithelial-mesenchymal transition in renal fibrosis through the Rac1/PI3K/AKT pathway.
Histone methyltransferase KMT2A promotes pulmonary fibrogenesis via targeting pro-fibrotic factor PU.1 in fibroblasts.
Luteolin Mitigates Photoaging Caused by UVA-Induced Fibroblast Senescence by Modulating Oxidative Stress Pathways.
Early assessment and treatment of ventricular remodeling in vivo via a targeted ultrasonic molecular probe loaded with oxygen and cholecystokinin.
Exploring the osteogenic effects of simiao wan through activation of the PI3K/AKT pathway in osteoblasts.
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
Enhanced oral nanomedicine utilizing biomineralized oncolytic virus for synergistic gastrointestinal cancer therapy.
Synergistic dual chemophysical FeCu-MOF scaffold with PEMF stimulation drives angiogenic-osteogenic coupling for bone regeneration.
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.
Incorporating Stem Cell-Derived Small Extracellular Vesicles into a Multifunctional OHAMA-EPL Hydrogel Spray for Rapid Healing of Infected Skin Wounds.
Tubuloside B alleviates con A-induced acute liver injury by inhibiting the IL-23/JAK2/STAT3 signaling pathway hyperactivation during Th17 cell differentiation.
Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.
Enhanced therapeutic efficacy of repeated bone marrow-derived MSC administration in a murine model of pulmonary fibrosis.
Lupiwighteone Ameliorates Diabetic Nephropathy-Induced Renal Fibrosis via SIRT1/NF-κB Signaling Pathway-Mediated Inflammatory Response.
Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
A Di-aptamer-functionalized scaffold promotes bone regeneration by facilitating the selective retention of MSCs and EPCs and then promoting crosstalk between osteogenesis and angiogenesis.
Mesenchymal Stem Cell-Derived Extracellular Vesicles Embedded in a Self-Adaptive Multifunctional Hydrogel for Rapid Healing of Infected Wounds.
Renal tubular epithelial IGFBP7 interacts with PKM2 to drive renal lipid accumulation and fibrosis.
Advanced Dynamic Slurry Circulation System for Precision 3D Bioprinting of Osteogenic Ceramics: Enhanced Stability, Mechanical Performance Optimization, and In Vitro Bioactivity Validation.
A Novel pH-Responsive Baicalein@Chitosan Hydrogel for the Topical Treatment of Herpes Simplex Virus Type 1 Skin Infections: Therapeutic Potential and Mechanisms.
Luteolin 7-Glucuronide in Artemisia rupestris L. Extract Attenuates Pulmonary Fibrosis by Inhibiting Fibroblast Activation and FMT via Targeting of TGF-β1.
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.
Knockout of C1q/tumor necrosis factor-related protein-9 aggravates cardiac fibrosis in diabetic mice by regulating YAP-mediated autophagy.
Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
Omaveloxolone ameliorates glucocorticoid-induced osteonecrosis of the femoral head by promoting osteogenesis and angiogenesis.
Copper ion-doped multifunctional hydrogel with mild photothermal enhancement promotes vascularized bone regeneration.
Targeting Bacteria-Induced Ferroptosis of Bone Marrow Mesenchymal Stem Cells to Promote the Repair of Infected Bone Defects.
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis.
Exogenous PRAS40 reduces KLF4 expression and alleviates hypertrophic scar fibrosis and collagen deposition through inhibiting mTORC1.
Empagliflozin attenuates liver fibrosis in high-fat diet/streptozotocin-induced mice by modulating gut microbiota.
The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl(4)-caused murine liver fibrosis in vivo.
LncRNA Snhg12/IGFBP3 axis is involved in liver fibrosis by promoting the proliferation and activation of mouse hepatic stellate cells.
Carnosol attenuates angiotensin II-induced cardiac remodeling and inflammation via directly binding to p38 and inhibiting p38 activation.
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4.
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Recombinant Slit2 attenuates tracheal fibroblast activation in benign central airway obstruction by inhibiting the TGF-β1/Smad3 signaling pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway.
Aristolochic acid I promotes renal tubulointerstitial fibrosis by up-regulating expression of indoleamine 2,3-dioxygenase-1 (IDO1).
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
Discoidin Domain Receptor 2 Contributes to Breast Cancer Progression and Chemoresistance by Interacting with Collagen Type I.
The hematopoietic activity of EPO is unfavorable to the treatment of bleomycin-induced pulmonary fibrosis in mice.
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Drug repurposing screens to identify potential drugs for chronic kidney disease by targeting prostaglandin E2 receptor.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.
β-elemene alleviates hyperglycemia-induced cardiac inflammation and remodeling by inhibiting the JAK/STAT3-NF-κB pathway.
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
RhoA vesicle trafficking-mediated transglutaminase 2 membrane translocation promotes IgA1 mesangial deposition in IgA nephropathy.
Tobacco toxins induce osteoporosis through ferroptosis.
Costunolide alleviates hyperglycaemia-induced diabetic cardiomyopathy via inhibiting inflammatory responses and oxidative stress.
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy.
[Lipopolysaccharide stimulates macrophages to secrete exosomes containing miR-155-5p to promote activation and migration of hepatic stellate cells].
Focal adhesion kinase induces cardiac remodeling through NF-κB-mediated inflammatory responses in diabetic cardiomyopathy.
Experimental Design of Vertical Distraction Osteogenesis Using Simple 3 Screws.
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
Facile preparation of a novel nanoemulsion based hyaluronic acid hydrogel loading with Poria cocos triterpenoids extract for wound dressing.
Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca2+ mishandling and atrial fibrosis in active immunization rabbit models.
Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis.
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Albumin-Based Silibinin Nanocrystals Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy.
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Exploring the Role of Lycium barbarum Polysaccharide in Corneal Injury Repair and Investigating the Relevant Mechanisms through In Vivo and In Vitro Experiments.
miR-146a-5p Alleviates Radiation-Induced Liver Fibrosis by Regulating PTPRA-SRC Signaling in Mice.
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways.
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Photothermal lipolysis accelerates ECM production via macrophage-derived ALOX15-mediated p38 MAPK activation in fibroblasts.
A sustained release of BMP2 in urine-derived stem cells enhances the osteogenic differentiation and the potential of bone regeneration.
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Erratum: Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization.
Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development.
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Primary Repair for Treating Acute Proximal Anterior Cruciate Ligament Tears: A Histological Analysis and Prospective Clinical Trial.
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1.
Ginsenoside Rc Promotes Bone Formation in Ovariectomy-Induced Osteoporosis In Vivo and Osteogenic Differentiation In Vitro.
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl(4)-caused liver fibrosis.
Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.
Zanubrutinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway.
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro.
miR-506-3p regulates TGF- 1 and affects dermal fibroblast proliferation, migration and collagen formation after thermal injury.
Ppic modulates CCl(4)-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.
Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats.
MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
Silencing Proteasome 26S Subunit ATPase 2 (PSMC2) Protects the Osteogenic Differentiation In Vitro and Osteogenesis In Vivo.
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma.
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.
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Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization.
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Inhibiting cGAS-STING to Preserve Mitochondrial-Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age-Related Tendinopathy.
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Decoding the spatiotemporal development of the blood-brain barrier in human cortex.
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Study on the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula by inhibiting M2 macrophage polarization and regulating TGF - β/SMAD signaling pathway.
Hong L, Sun Y, Hou H, Zhang J, Shi W, Yang Y, Fan X, Zhu J
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N-acetylglucosamine ameliorates the transition from acute kidney injury to chronic kidney disease by reducing the accumulation of lipid droplets.
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Advanced Hydrogel/Electrospun Nanofiber Composite Scaffold With Sequential Bioactive Factor Release for Rotator Cuff Repair.
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Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
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Small-molecule LF3 alleviates angiotensin II-induced cardiac dysfunction via attenuating cardiac fibrosis.
Liu X, Zhang C, Jiang W, Wu J, Li G, Zhao J, Sun X, Huang J, Zhao L
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SLIT3/ROBO1 axis contributes to angiogenic-osteogenic coupling in endothelial progenitor cells and peripheral blood mesenchymal stem cells.
Rong Q, Ma L, Wang M, Liu Q, Zhang Y, Yuan Z, Tan X
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Inhalable lipid nanoparticles for macrophage-specific STING gene editing to ameliorate pulmonary fibrosis.
Wang Y, Liu X, Xuan W, Huang W, Zhu Y, Mao C, Liu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2026 Mar 6;
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Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
Zhang H, Liu Y, Zhang S, Wang Z, Zhang X, Zhang Y, Zhang J, Liang S, Li C, Su M, Tian Z, Luo L
Journal of nanobiotechnology 2026 Mar 16;24(1)
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Mechanism of macrophage mitochondrial transfer in CBNPs induced EndMT of pulmonary microvascular endothelial cells.
Wang M, Wang Q, Liu Q, Zhang S, Xie Y, Zhang T, Yang Z, Bao L, Pang Y, Shi D, Cheng J, Niu Y, Zhang Z, Zhang R
Journal of hazardous materials 2026 Mar 1;505:141468
Journal of hazardous materials 2026 Mar 1;505:141468
Hyaluronic acid-based reactive oxygen species responsive nanocomposite hydrogel for sequential drug delivery and effective prevention of postoperative abdominal adhesions.
Gong Y, Xiao D, Zhang T, Shi X, Wang S, Huang Y, Zhao C
Carbohydrate polymers 2026 Jun 1;381:125148
Carbohydrate polymers 2026 Jun 1;381:125148
FOSL1 mediates collagen synthesis and myofibroblast transformation in aortic fibroblasts under Ang II-induced aortic dissection conditions.
Zhong L, Zhang H, Huang Y, Zhang L, Zhang L, Liu Q, Liao Y, Zhang Q, Fu W, Wang C, Li X, Chen L, Li Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2026 Jun 1;221:107504
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2026 Jun 1;221:107504
Biodegradable Mg(2+)-releasing piezoelectric scaffold for segmental bone defect repair.
Wang C, Zhang T, Liu J, Wang X, Gao C, Chen J, Feng J, Dong Z, Wang X, Li Y, Zhao M, Li F, Yu Y, Cai Q, Tian H
Bioactive materials 2026 Jul;61:743-757
Bioactive materials 2026 Jul;61:743-757
Lathyrane diterpenoids with anti-renal fibrotic activity from the aboveground parts of Euphorbia wallichii.
Ma RF, Liu KY, Pan YB, Zhang H
Phytochemistry 2026 Jul;247:114875
Phytochemistry 2026 Jul;247:114875
FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome.
Zhang D, Liu W, Sun T, Xiao Y, Chen Q, Huang X, Wang X, Qi Q, Wang H, Wang T
Cell proliferation 2026 Jan;59(1):e70075
Cell proliferation 2026 Jan;59(1):e70075
Early Intervention of Subchondral Bone Resorption Mitigates Cartilage Degeneration in TMJOA.
Cao MN, Feng SY, Gao CC, Xiao Y, Li YX, Lei J, Fu KY
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Jan;55(1):133-146
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2026 Jan;55(1):133-146
Gas diffusion-mediated single-sided in situ gradient mineralized silk fibroin membrane for enhanced guided bone regeneration.
Li Z, Kong Y, Zhang Q, Han J, Chen K, Ma B
Dental materials : official publication of the Academy of Dental Materials 2026 Jan;42(1):157-167
Dental materials : official publication of the Academy of Dental Materials 2026 Jan;42(1):157-167
Transdermal delivery of salvianolic acid B using thermosensitive hydrogel for the treatment of skin photoaging.
Wu L, Tao Y, Xu Y, Liang Z, Zhao Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(1):113-127
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(1):113-127
Dual-PPARα/δ agonist H11 alleviates tendinopathy via modulating the Nrf2/HO-1/GPX4 pathway.
Lu Y, Yang S, Liu H, Zhang Y, Li Z, Lu J, Jiang Q, Xu X
Free radical biology & medicine 2026 Jan;242:333-344
Free radical biology & medicine 2026 Jan;242:333-344
SLC22A17 affects the development of urethral stricture by promoting ferroptosis and inhibiting the activation of fibroblasts.
Liang T, Deng C, Guo H, Dai Z, Lu Y, Jiang Y, Chen W
Biochemical and biophysical research communications 2026 Jan 8;795:153118
Biochemical and biophysical research communications 2026 Jan 8;795:153118
From rosemary and coffee to bioactive nanovesicles: exploring new frontiers in food functional ingredients.
d'Adduzio L, Aiello G, Musazzi U, Bollati C, Frigerio G, Fanzaga M, Musco MS, Lammi C
NPJ science of food 2026 Jan 28;10(1)
NPJ science of food 2026 Jan 28;10(1)
Targeting sorting nexin 3 to treat pulmonary fibrosis by dual modulating Wnt/β-catenin signaling.
Ma D, Yu W, Zhou H, Lin R, Sun X, Peng M, Lin C, Du H, Li Y, Liang H, Sun D, Liu P, Lu J
Cell death & disease 2026 Jan 15;17(1):43
Cell death & disease 2026 Jan 15;17(1):43
An Immune-privileged niche mediates immunotherapy resistance in esophageal carcinoma.
Wan L, Li B, Ma T, Wang M, Xie F, Ge H, Xiao Z, Chen X, Meng L, Zhang L, Xie K, Wang Q
Journal for immunotherapy of cancer 2026 Jan 14;14(1)
Journal for immunotherapy of cancer 2026 Jan 14;14(1)
Injectable hydrogels for osteomyelitis treatment induce metabolic reprogramming for protection against reinfection.
Chen H, Wei L, Yu Q, Wang C, Fan H, Li M, Dong R, Ma Y, Jiang J, Deng L, Wu MX, Lu M
Nature communications 2026 Jan 13;17(1):1613
Nature communications 2026 Jan 13;17(1):1613
Biomimetic Multilayered Gas-Foaming Scaffold with Sustained bFGF Delivery for Annulus Fibrosus Regeneration.
Chen Y, Li Y, Wei Z, Du L, Qian M, Wang J, Mo X, Deng Z, Ye X, Yu J
Advanced healthcare materials 2026 Feb;15(7):e02833
Advanced healthcare materials 2026 Feb;15(7):e02833
DOT1L promotes phenotypic transition of vascular smooth muscle cells following vascular injury in diabetes through activation of the FGFR4/PI3K/AKT/Jag/Notch signaling pathway.
Zhang J, Wu D, Cheng C, Yang Z, Chen Z, Liu L, Li W, Wang W, Huang C, Yang J
Cellular signalling 2026 Feb;138:112223
Cellular signalling 2026 Feb;138:112223
Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF-β1.
Peng L, Zhang L, Fan Y, Huang S, Zhao Q, Han C, Hao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e05256
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e05256
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Zhou Q, Liu W, Ge J, Liu X, Wang H, Fu W, Deng D
Pharmaceutics 2026 Feb 9;18(2)
Pharmaceutics 2026 Feb 9;18(2)
Treadmill running modulates infrapatellar fat pad remodeling in osteoarthritic rats in an intensity-dependent manner.
Chen Z, Li G, Deng H, Hu Z, Wang Q, He Z
BMC sports science, medicine & rehabilitation 2026 Feb 5;18(1)
BMC sports science, medicine & rehabilitation 2026 Feb 5;18(1)
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Yi D, Wu Z, Li X, Shao B, Xiao Y, Li T, Zhang X, Zhu J, Yang T, Deng Y, Huang T, Qiu T, Bai J, Shi X, Wu C, Wu Z, Sun X, Wang N
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Integrated network pharmacology and bioinformatics analysis reveals MME as key target of Notoginsenoside R1 in diabetic nephropathy.
Gan X, Liang M, Shadekejiang H, Hong H, Lu J, Li X, Zhang X, Lu C
BMC complementary medicine and therapies 2026 Feb 1;26(1)
BMC complementary medicine and therapies 2026 Feb 1;26(1)
BMP2@PDA-LDH functionalized coating on ZK60 magnesium alloy: Enhanced corrosion resistance and promoted bone defect regeneration.
Wang T, Zhou W, Li S, Le K, Zhang X, Wang J, Xie S, Wan Y, Xi W
Colloids and surfaces. B, Biointerfaces 2026 Aug;264:115650
Colloids and surfaces. B, Biointerfaces 2026 Aug;264:115650
LCZ696 (Sac/Val) protects against high-fat diet-induced kidney injury in mice by targeting ROCK2 to suppress ROCK2/NF-κB signaling.
Wang W, Huang Y, Guo X, Cao Z, Jiang H, Zheng Q, Shi S, Huang P, Zhou J, Hu F, Qian J
Cellular signalling 2026 Aug;144:112536
Cellular signalling 2026 Aug;144:112536
VEGF-sustained regulation and hydrogel-activated graded porous titanium scaffold for functional regeneration of the tendon-bone interface.
Lin T, Li J, Luo L, Sang H, Vashisth MK, Shen J, Luo X, Xu L, Pan J, Huang W
Materials today. Bio 2026 Apr;37:102903
Materials today. Bio 2026 Apr;37:102903
CCT7 Regulates TRAF6-Mediated Autophagy to Promote Posttraumatic Joint Contracture.
Li Y, Zhang W, Xu W, Huang Y, Cai H, Zhang N, Liang T, Liu G
Journal of cellular and molecular medicine 2026 Apr;30(7):e71051
Journal of cellular and molecular medicine 2026 Apr;30(7):e71051
Gamma delta T cells promote intestinal fibrosis via an interleukin-17A-induced transforming growth factor-beta signaling pathway in fibroblasts.
Li Y, Chen M, Chen C, Huang B, Liu F, Liang D, Sun D, He Z, Lan C
Molecular immunology 2026 Apr;192:21-31
Molecular immunology 2026 Apr;192:21-31
An injectable photo-crosslinking silk hydrogel system with biphasic release of BTXA and 5-Fu promotes scarless wound healing.
Xu M, Wang X, Zhou Z, Wang L, Zhou J, Hu X, Wang Y, Wu T
RSC advances 2026 Apr 8;16(21):18938-18951
RSC advances 2026 Apr 8;16(21):18938-18951
Multifunctional 3D-Printed Titanium Alloy Composite-Coated Scaffold for Modulating the Immune Microenvironment and Promoting Osteogenesis.
Ni R, Wang M, Chen Z, Wu Z, Jing Z, Li W
ACS applied materials & interfaces 2026 Apr 22;18(15):21844-21860
ACS applied materials & interfaces 2026 Apr 22;18(15):21844-21860
Targeting Tumor Microenvironment-Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer.
Shinder BM, Lee YS, Mao N, Salsabeel N, Zhang Z, Kaur H, Chen X, Chang Q, de Stanchina E, Gopalan A, Sawyers CL, Carver BS
Molecular cancer therapeutics 2026 Apr 2;25(4):662-671
Molecular cancer therapeutics 2026 Apr 2;25(4):662-671
Fibrosis suppressive effect and mechanism of CaSR positive allosteric modulators/p-dioxanone copolymers.
Feng C, Liu Y, Zhang C, Niu L, Dong J, Wang B
Drug delivery and translational research 2026 Apr 14;
Drug delivery and translational research 2026 Apr 14;
Salidroside ameliorates skin aging in male mice by promoting collagen regeneration via modulation of FOS and MMP9.
Wang Z, Yan X, Li X, Zhu H, Wang Y, Fan X, Lu X, Li X, Yang M, Zhang C, Wu Y
Biogerontology 2026 Apr 10;27(3)
Biogerontology 2026 Apr 10;27(3)
Store-operated Ca(2+) entry contributes to the ASM phenotype transition in asthma.
Ni H, Li T, Chen J, Wei Y, Xia M, Wang Q
Experimental lung research 2025;51(1):23-37
Experimental lung research 2025;51(1):23-37
Fibroblast Activation Protein-Targeted CAR-T Cells Induce Apoptosis in Murine Cardiac Myofibroblasts.
Li H, Zheng Q, Jiang Y, Yang L, Li S, Yang P, Yin G, Sun L
Cardiovascular therapeutics 2025;2025:7230505
Cardiovascular therapeutics 2025;2025:7230505
Exploring The Role of TOP2A in the Intersection of Pathogenic Mechanisms Between Rheumatoid Arthritis and Idiopathic Pulmonary Fibrosis Based on Bioinformatics.
Shi S, Hong X, Zhang Y, Chen S, Huang X, Zheng G, Hu B, Lu M, Li W, Zhong Y, Sun G, Ouyang Y
Journal of inflammation research 2025;18:3449-3468
Journal of inflammation research 2025;18:3449-3468
Curculigoside alleviates ferroptosis in renal interstitial fibrosis by regulating the Nrf2/HO-1 signaling pathway.
Liu T, Sui M, Yu C, Bao Y, Xing L, Hou D, Xie R
American journal of translational research 2025;17(10):7640-7658
American journal of translational research 2025;17(10):7640-7658
Exosomes derived from Panax notoginseng promote osteogenic differentiation of rBMSCs via the PI3K/AKT signaling pathway.
Wu N, Zhang L, Guo H
Frontiers in pharmacology 2025;16:1682548
Frontiers in pharmacology 2025;16:1682548
Thymoquinone and aerobic exercise mitigate HFpEF-induced cardiac injury via Apaf1/Cycs axis regulation.
Pei Z, Gao S, Yang J, Liu C, Pan Y
Frontiers in pharmacology 2025;16:1672570
Frontiers in pharmacology 2025;16:1672570
Ivermectin attenuates Schistosoma japonicum-induced liver fibrosis and is associated with downregulation of YAP signaling.
Xuan M, Zhang P, Guo J, Guan F, Lu S, Liu W
Frontiers in cellular and infection microbiology 2025;15:1678067
Frontiers in cellular and infection microbiology 2025;15:1678067
The endogenous glutamatergic transmitter system promotes collagen synthesis in cardiac fibroblasts under hypoxia.
Wang R, Yuan X, Xie T, Zhao X, Li J, Zhang X, Lv C
Frontiers in cardiovascular medicine 2025;12:1638650
Frontiers in cardiovascular medicine 2025;12:1638650
Low hydrostatic pressure promotes functional homeostasis of nucleus pulposus cells through the TRPV4/CRT/FA complex axis.
Hu J, Zhu Y, Pang Z, Li X, Zhang H, Li X, Gao Y, Wang Y, Li P, Zhou Q
Frontiers in medicine 2025;12:1531907
Frontiers in medicine 2025;12:1531907
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis.
Huang QH, Tang XY, Huang QY, Zhi SB, Zheng XQ, Gan CY, Huang MF, Pan ZF, Zhong ZX
Biochemical pharmacology 2025 Sep;239:117014
Biochemical pharmacology 2025 Sep;239:117014
Gut Metabolite Indole-3-Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging-Related Myocardial Fibrosis.
Lu J, Wang H, Zhang H, Li J, Li H, Chen Q, Han D, Liu J, Lv L, Xiong J, Yuan K, Wei X, Sheng S, Liu F, Shi Y, Dong Z, Li Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e01070
Integration of network pharmacology and transcriptomics to reveal the mechanism of Paeoniae Radix Alba Polysaccharide in alleviating hepatic fibrosis.
Fan X, Gao J, Liu S, Hua J, Shao D, Jia L, Shen Y, Wang Z, Jin Z, Wang J
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120357
Vericiguat as a novel PPARα ligand alleviates pressure-overload-induced heart failure.
Zhang P, Yuan C, Zhan Z, Zhou J, Huang P, Wang W, Qian J, Shan P
Toxicology and applied pharmacology 2025 Oct;503:117473
Toxicology and applied pharmacology 2025 Oct;503:117473
High-Yield Extruded Nanovesicles From Adipose Stem Cells Promote High-Quality Healing of Diabetic Wound Through WNT/β-Catenin Pathway Activation.
Yao T, Liu L, Miao Y, Li X, Yu Y, Sun R, Zhang Y, Cui L, Ma X
Journal of cellular and molecular medicine 2025 Oct;29(19):e70877
Journal of cellular and molecular medicine 2025 Oct;29(19):e70877
ADSC-enriched adipose extract alleviates cartilage fibrosis in temporomandibular joint osteoarthritis by inhibiting chondrocyte senescence.
Zhang Z, Jin D, Jing B, Zhou S, Sun Y, Van Dessel J, Ren R, Liu F, Zhang M, Li Y
Journal of translational medicine 2025 Oct 9;23(1):1072
Journal of translational medicine 2025 Oct 9;23(1):1072
Anemoside B4 improves cardiac function after myocardial infarction by regulating HTR2A/ERK pathway.
Lv M, Sun Q, Yu Y, Yu D
International immunopharmacology 2025 Oct 30;164:115394
International immunopharmacology 2025 Oct 30;164:115394
SIRT5 induces glomerular sclerosis in diabetic nephropathy through p53.
Liu S, Xu Z, Li X, Zhang Y, Cai Z, Yin X, Wang J
International immunopharmacology 2025 Oct 30;164:115352
International immunopharmacology 2025 Oct 30;164:115352
The β-glucan from Lentinus alleviates UVB-induced dermal fibroblasts senescence and skin photoaging.
Wei K, He L, Li X, Wu M, Wang H, Hu L, Xu H, Zhang Y, Zhou L, Xu X, Guo L
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
International journal of biological macromolecules 2025 Nov;329(Pt 2):147834
An Ile to Met polymorphism in ADCY9 promotes airway obstruction and remodeling in asthma.
Liang LM, Cai PC, Yu F, He XL, Song LJ, Lu YZ, Niu Q, Zhou YY, Jiang LJ, Jiang YH, Jia ZH, Zhao LQ, Wang M, Cheng PP, Chen SJ, Feng X, Li Q, Cui XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168015
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):168015
Blocking IL-6 down-regulates PD-L1 expression and mitigates pulmonary fibrosis by inhibiting the STAT3 signaling pathway.
Hu X, Tan J, Wang Y, Luan R, Ding D, Yue M, Zhao M, Xue Q, Yang J
Cellular signalling 2025 Nov;135:112019
Cellular signalling 2025 Nov;135:112019
Isobavachin alleviates hyperuricemia-induced bone loss by GPR35-NLRP3 signal.
Cen X, Mai S, Huang R, Lin S, Chen Y, Zhang S, Zhao P, Guo D, Liang X, Zhao Y, Feng H, Xiao Z, Lu X, Wan H, Wang H, Xie D, Pang J, Zhang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157368
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157368
Single-cell RNA sequencing revealed the association between proximal tubular epithelial cells and renal interstitial cells in chronic kidney disease progression.
Xu Y, Ye X, Peng Y, Wu S, Gao L, Huang X, Lu L, Lu J, Liu X
Scientific reports 2025 Nov 24;15(1):45256
Scientific reports 2025 Nov 24;15(1):45256
JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7.
Shen SR, Huang ZQ, Yang YD, Han JB, Fang ZM, Guan Y, Xu JC, Min JL, Wang Y, Wu GJ, Xiao ZX, Luo W, Huang ZQ, Liang G
Acta pharmacologica Sinica 2025 May;46(5):1275-1288
Acta pharmacologica Sinica 2025 May;46(5):1275-1288
Notch1 signaling regulates Sox9 and VEGFA expression and governs BMP2-induced endochondral ossification of mesenchymal stem cells.
Zou J, Du C, Liu S, Zhao P, Gao S, Chen B, Wu X, Huang W, Zhu Z, Liao J
Genes & diseases 2025 May;12(3):101336
Genes & diseases 2025 May;12(3):101336
Semaphorin 3E-Plexin D1 Axis Drives Lung Fibrosis through ErbB2-Mediated Fibroblast Activation.
Deng Z, Chen J, Yang R, Zhan Y, Chen S, Zhang J, Fu H, Gu Y, Huang Q, Wu J, Shan L, Gounni AS, Xie J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2415007
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(18):e2415007
Transcriptional Study of Radiofrequency Device Using Experimental Mouse Model.
Li X, Wang Z, Li X, Fan X, Lu X, Li Y, Pan Y, Zhu Z, Zhu M, Li W, Chan L, Yu S, Pan Y, Wu Y
International journal of molecular sciences 2025 May 7;26(9)
International journal of molecular sciences 2025 May 7;26(9)
Dual-step photo-induced self-assembled hydrogel for endogenous oral mucosal wound healing.
Fang S, Zhou Q, Zhou M, Li C, Xu H, Tang H, Zhang W, Guo R, Wei X, Zhang R
Light, science & applications 2025 May 15;14(1):186
Light, science & applications 2025 May 15;14(1):186
A Highly Bioactive Organic-Inorganic Nanoparticle for Activating Wnt10b Mediated Osteogenesis by Specifically Anchor CCN3 Protein.
Qiu Y, Wang C, Yang Y, Xu S, Huang H, Zhang L, Lei B, Zhao F
Advanced healthcare materials 2025 Mar;14(7):e2404075
Advanced healthcare materials 2025 Mar;14(7):e2404075
M2 macrophages promote PKM2 production in fibroblasts to alleviate UVB-induced photoaging.
Jia S, Shi N, Lu M, Wang X, Qi Y, Wang X, Zhao J, Jiang D
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Cell cycle (Georgetown, Tex.) 2025 Mar-Apr;24(5-8):86-102
Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA(+) macrophages contribute to atherosclerotic plaque formation.
Li M, Wu L, Wen Y, Wang A, Zhou X, Ren L, Lu Q, Li F, Zhu L, Tang C
Cellular and molecular life sciences : CMLS 2025 Mar 30;82(1):134
Cellular and molecular life sciences : CMLS 2025 Mar 30;82(1):134
CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B.
Li YY, Meng FL, Zhou SY, Du JM, Li WJ, Liu QY, Wu L, Zhao MM, Jin Y, Zhang QY, Li Y, Su GH
Scientific reports 2025 Mar 22;15(1):9985
Scientific reports 2025 Mar 22;15(1):9985
Therapeutic inhibition of PHF21B attenuates pathological cardiac hypertrophy by inhibiting the BMP4/GSK3β/β-catenin axis.
Sheng S, Liu G, Lv P, Liu J, Lv L, Yuan M, Luo D, Xiong J, Dong P, Zhang J, Xie B, Dong Z, Shi Y
European journal of pharmacology 2025 Mar 15;991:177346
European journal of pharmacology 2025 Mar 15;991:177346
Baicalin reduced vandetanib induced myocardial injury by regulating redox balance and NLRP3 inflammasome pathway.
Wang F, Li J, Zhang Z, Huang G, Zhang X, Liu Q, Xiao W, Liu F, Sun J, Liu Y, Ma Y, Zhuang R, Du Y, Wang X, Gao C, Gu X
Tissue & cell 2025 Jun;94:102795
Tissue & cell 2025 Jun;94:102795
Sequential SDF-1/CGRP-releasing smart composite hydrogel promotes osteoporotic fracture healing by targeting sensory nerve-regulated bone remodeling.
Wang Y, Pan Z, Wang Q, Shu Y, Tan Z, Chen Y, He J, Wang J, Wang J, Yan J
Materials today. Bio 2025 Jun;32:101750
Materials today. Bio 2025 Jun;32:101750
Cerebral [(18)F]AIF-FAPI-42-Based PET Imaging of Fibroblast Activation Protein for Non-invasive Quantification of Fibrosis After Ischemic Stroke.
Tang P, Liu Y, Peng S, Cai Z, Tang G, Zhou Z, Hu K, Zhong Y
Translational stroke research 2025 Jun;16(3):848-858
Translational stroke research 2025 Jun;16(3):848-858
Diabetic wound healing breakthrough: theaflavin-3, 3'-digallate nanoparticles@hydrogel activates the TGF-β1/SMAD3 pathway.
Dong X, Miao J, Wu L, Kong Z, Liu Z, Jia D, Zhai Q, Zhang D, Xu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156617
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156617
Micro/Nanofibrous Polycaprolactone Scaffolds Loaded with Gentamicin for Improved Antimicrobial Activities under Seawater Immersion.
Liu K, Su Y, Wei B, Guo X, Zhang Y, Wang S, Zhang S, Kang Y, Yu X, Zhu H, He J
Advanced healthcare materials 2025 Jun;14(16):e2501352
Advanced healthcare materials 2025 Jun;14(16):e2501352
Mast cell tryptase-PAR2 axis promotes ovarian fibrosis through RNF152-mediated stabilization of Bcl-xL.
Zhang X, Zhang J, Wang C
Journal of ovarian research 2025 Jun 5;18(1):122
Journal of ovarian research 2025 Jun 5;18(1):122
TIMP1 regulation of cardiac fibroblast proliferation via the TGF-β/Smad pathway in an in vitro model of atrial fibrillation.
Zhou Y, Zhang L, Zhang W, Gong Q, Zhang Z, Xu N, Wilson-Smith AR, Chen N
Journal of thoracic disease 2025 Jun 30;17(6):4249-4263
Journal of thoracic disease 2025 Jun 30;17(6):4249-4263
Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling.
Wang D, Tan Q, Zheng Q, Ma Y, Feng L
European journal of histochemistry : EJH 2025 Jun 17;69(3)
European journal of histochemistry : EJH 2025 Jun 17;69(3)
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Dong C, Zhou Y, Shen X, Hu S, Duan K, Chen T, Li W, Sun X, Li P, Wang P, Han Y, Li D, Zhi Q, Zhou J
Cell death & disease 2025 Jun 11;16(1):444
Cell death & disease 2025 Jun 11;16(1):444
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
Jiang J, Li Y, Chen Y, Wu Q, Ding S
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
Irisin attenuates liver fibrosis by regulating energy metabolism and HMGB1/β-catenin signaling in hepatic stellate cells.
Li F, Liu X, Bai N, Li Y, Hou M, Hou Y, Liu Y, Wang X, He Q, Li J
European journal of pharmacology 2025 Jul 5;998:177519
European journal of pharmacology 2025 Jul 5;998:177519
Hypoxia Induces HIF-1α Activation in Tendon Stem Cells to Enhance Extracellular Vesicle-Mediated Tendon Repair.
Wu Y, Zhang T, Miao Y, Zhang A, Wang S, Li X, Liu H, Guo Y, Sun Q, Li Z
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
ACS applied materials & interfaces 2025 Jul 30;17(30):42637-42657
Pantothenic acid ameliorates hepatic fibrosis by targeting IGFBP6 to regulate the TGF-β/SMADs pathway.
Jin Z, Jin Z, Liu Z, Yin Y, Zhang Y, Zhang Y, Kang J, Fang Y, Jiang W, Ning B
Communications biology 2025 Jul 29;8(1):1127
Communications biology 2025 Jul 29;8(1):1127
FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation.
Wu HY, Han L, Ran T, Sun Y, Zhang QX, Huang T, Zou GL, Zhang Y, Zhou YM, Lin GY, Chen SJ, Wang JL, Pan C, Lu F, Pu HF, Zhao XK
World journal of gastroenterology 2025 Jul 28;31(28):107361
World journal of gastroenterology 2025 Jul 28;31(28):107361
Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest.
Casey-Clyde T, Liu SJ, Pelonero A, Serrano JAC, Teng C, Jang YG, Vasudevan HN, Padmanabhan A, Bush JO, Raleigh DR
bioRxiv : the preprint server for biology 2025 Jul 21;
bioRxiv : the preprint server for biology 2025 Jul 21;
H3K36me3 modification by SETD2 is essential for Col11a2 and Sema3e transcription to maintain dentinogenesis in mice.
Niu J, Fu J, Feng H, Han J, Chen Z, Yang G, Yuan G
Development (Cambridge, England) 2025 Jul 15;152(14)
Development (Cambridge, England) 2025 Jul 15;152(14)
Apoptotic extracellular vesicles derived from human dental pulp stem cells facilitate periodontal tissue regeneration.
Xia J, Zhang Z, Weng J, Zhu G, Xu Z, Zeng L, Pathak JL, Yu L
BMC oral health 2025 Jul 11;25(1):1150
BMC oral health 2025 Jul 11;25(1):1150
Proteomics analysis revealed the therapeutic role of adipose-derived mesenchymal stem cells on radiation-induced colorectal fibrosis in rats.
Thandar M, Zhang L, Yang X, Chi P, Li Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117763
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jan;182:117763
Sang-Bai-Pi extract and its constituent regiafuran C ameliorate renal fibrosis through TGF-β/Smad and Wnt/β-catenin signaling pathways.
Wei QH, Pan YB, Tian LL, Wang YS, Wang JY, Liu X, Zhang H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156351
Bie Jia Jian pill ameliorates BDL-induced cholestatic hepatic fibrosis in rats by regulating intestinal microbial composition and TMAO-mediated PI3K/AKT signaling pathway.
Cui X, Zhang R, Li Y, Li P, Liu Y, Yu X, Zhou J, Wang L, Tian X, Li H, Zhang S, Lan T, Li X, Zhang G, Li J, Liu Z
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118910
Journal of ethnopharmacology 2025 Jan 30;337(Pt 2):118910
Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.
Xie J, Huang H, Xu S, Zhou K, Chen X, Fang J, Zhao F
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Journal of controlled release : official journal of the Controlled Release Society 2025 Jan 10;377:446-457
Sunscreen Formula of FeO(OH)·H(2)O/TiO(2) With Spectral Selectivity to Enhance Collagen Biosynthesis via Fibroblast Test.
Zhang X, Wen X, Wang Y, Jiang F, Chen Y, Liu Z
Journal of cosmetic dermatology 2025 Feb;24(2):e70060
Journal of cosmetic dermatology 2025 Feb;24(2):e70060
Dedicator of cytokinesis protein 2 activates the epithelial-mesenchymal transition in renal fibrosis through the Rac1/PI3K/AKT pathway.
Jia Y, Sun J, Chen S, Bian Y, Jiang A, Liang H, Du X
Biochimica et biophysica acta. Molecular cell research 2025 Feb;1872(2):119894
Biochimica et biophysica acta. Molecular cell research 2025 Feb;1872(2):119894
Histone methyltransferase KMT2A promotes pulmonary fibrogenesis via targeting pro-fibrotic factor PU.1 in fibroblasts.
Lyu W, Wang H, Ji T, Liu L, Chen H, Fan L, Zhong G, Wan N, Chen S, Chen J, Cai H, Xu H, Wang D, Dai J
Clinical and translational medicine 2025 Feb;15(2):e70217
Clinical and translational medicine 2025 Feb;15(2):e70217
Luteolin Mitigates Photoaging Caused by UVA-Induced Fibroblast Senescence by Modulating Oxidative Stress Pathways.
Yan Y, Huang H, Su T, Huang W, Wu X, Chen X, Ye S, Zhong J, Li C, Li Y
International journal of molecular sciences 2025 Feb 20;26(5)
International journal of molecular sciences 2025 Feb 20;26(5)
Early assessment and treatment of ventricular remodeling in vivo via a targeted ultrasonic molecular probe loaded with oxygen and cholecystokinin.
Wang C, Cheng H, Dong X, Zhan Y, Liu Y, Wu N, Tang R, He H, Cao Y, Yang L, Ren J, Li X, Li P
Journal of nanobiotechnology 2025 Feb 12;23(1):104
Journal of nanobiotechnology 2025 Feb 12;23(1):104
Exploring the osteogenic effects of simiao wan through activation of the PI3K/AKT pathway in osteoblasts.
Xin L, Feng HC, Zhang Q, Cen XL, Huang RR, Tan GY, Zhang Q
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119023
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119023
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
Hao R, Wang X, Liu C, Xue J
Inflammation 2025 Dec;48(6):4475-4491
Inflammation 2025 Dec;48(6):4475-4491
Enhanced oral nanomedicine utilizing biomineralized oncolytic virus for synergistic gastrointestinal cancer therapy.
Hu Z, Sun Y, Yu S, Zheng F, Yan Z, Lu N, Ye L, Yuan S, Zhu Y, Deng J, Wang J, Bai Y
Materials today. Bio 2025 Dec;35:102583
Materials today. Bio 2025 Dec;35:102583
Synergistic dual chemophysical FeCu-MOF scaffold with PEMF stimulation drives angiogenic-osteogenic coupling for bone regeneration.
Guo D, Wang W, Zhao D, Chen T, Ma X, Li Y, Zhang X
Materials today. Bio 2025 Dec;35:102324
Materials today. Bio 2025 Dec;35:102324
A H(2)-bioreactor for mitochondrial rehabilitation in infected bone defects regeneration.
Kong C, Si C, Liu H, Wang Y, Qiao J, Tang X, Sun H, Zhang J, Chang B
Materials today. Bio 2025 Dec;35:102295
Materials today. Bio 2025 Dec;35:102295
Targeting PBK in the fibroblast-to-myofibroblast transition: A novel therapeutic strategy for IPF.
Dong RH, Li X, Yue HH, Zhang FQ, He JH, Dou XR, Li H, Li YH, Li T, Zhang HL
Biochemical pharmacology 2025 Dec;242(Pt 2):117283
Biochemical pharmacology 2025 Dec;242(Pt 2):117283
Incorporating Stem Cell-Derived Small Extracellular Vesicles into a Multifunctional OHAMA-EPL Hydrogel Spray for Rapid Healing of Infected Skin Wounds.
He M, Wei Y, Chen X, Li J, Kang J, Li B, Liu D, Cai H
Advanced healthcare materials 2025 Dec;14(32):e04147
Advanced healthcare materials 2025 Dec;14(32):e04147
Tubuloside B alleviates con A-induced acute liver injury by inhibiting the IL-23/JAK2/STAT3 signaling pathway hyperactivation during Th17 cell differentiation.
Luo J, Yu Z, An W, Li M, Wei H, Wang Z, He L, Xiao F, Wei H
International immunopharmacology 2025 Dec 3;166:115586
International immunopharmacology 2025 Dec 3;166:115586
Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.
Fan Y, Tian Z, Zheng H, Xu R, Li B, Wang S, Huang Z, Wang M, Ding D, Zhao J, Xie J
International immunopharmacology 2025 Dec 3;166:115554
International immunopharmacology 2025 Dec 3;166:115554
Enhanced therapeutic efficacy of repeated bone marrow-derived MSC administration in a murine model of pulmonary fibrosis.
Zhou Z, Ding J, Han S, Duan Y, Chao J, Huang J
Stem cell research & therapy 2025 Dec 23;17(1):48
Stem cell research & therapy 2025 Dec 23;17(1):48
Lupiwighteone Ameliorates Diabetic Nephropathy-Induced Renal Fibrosis via SIRT1/NF-κB Signaling Pathway-Mediated Inflammatory Response.
Yang H, Pan H, Chen Z, Wang Y, Jiang W, Fang H, Yan K, Ren J, Tang L, Xu S
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31942-31956
Journal of agricultural and food chemistry 2025 Dec 17;73(50):31942-31956
Kirenol attenuates pressure overload-induced heart failure by enhancing autophagy in macrophages.
Huang Z, Pan L, Xiao Z, Rao F, Yakupu W, Rouzi A, Cheng K, Pang Y, Su Y, Wu D
International journal of cardiology 2025 Dec 1;440:133681
International journal of cardiology 2025 Dec 1;440:133681
Renal insulin-like growth factor binding-protein 7 is a critical promoter of progressive diabetic kidney disease.
Yu JT, Hu XW, Wang JN, Yang Q, Li XY, Shan RR, Pu T, Hou R, Shen XY, Wang YQ, Zhang F, Yu XW, Wang J, Li FH, Wen JG, Fan Y, Jin J, Jiang YY, Meng XM
Nature communications 2025 Dec 1;17(1):30
Nature communications 2025 Dec 1;17(1):30
A Di-aptamer-functionalized scaffold promotes bone regeneration by facilitating the selective retention of MSCs and EPCs and then promoting crosstalk between osteogenesis and angiogenesis.
Yang Q, Zhou J, Yang M, Wei J, Gui Y, Yang F, He S, Cai J, Yu B, Dai Q, Tang Z, Hou T
Biomaterials 2025 Aug;319:123197
Biomaterials 2025 Aug;319:123197
Mesenchymal Stem Cell-Derived Extracellular Vesicles Embedded in a Self-Adaptive Multifunctional Hydrogel for Rapid Healing of Infected Wounds.
Chen X, Wang X, He M, Kang J, Gu J, Wei Y, Li J, Li B, Hong X, Mao X, Liu D, Cai H
Advanced healthcare materials 2025 Aug;14(20):e2500980
Advanced healthcare materials 2025 Aug;14(20):e2500980
Renal tubular epithelial IGFBP7 interacts with PKM2 to drive renal lipid accumulation and fibrosis.
Yu JT, Xie SS, Shen XY, Li Z, Hu XW, Zhang Y, Dong ZH, Wang JN, Li XY, Dong YH, Li C, Ji ML, Suo XG, Yang C, Jin J, Wang W, Wen JG, Liu MM, Li L, Yang Q, Meng XM
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Aug 6;33(8):3757-3777
Molecular therapy : the journal of the American Society of Gene Therapy 2025 Aug 6;33(8):3757-3777
Advanced Dynamic Slurry Circulation System for Precision 3D Bioprinting of Osteogenic Ceramics: Enhanced Stability, Mechanical Performance Optimization, and In Vitro Bioactivity Validation.
He J, Xie M, Luo S, Tang G, Zou Z, Teng J, Zhao B, Cui D, Zhou T, Yang L, Ye C
ACS omega 2025 Aug 5;10(30):32895-32906
ACS omega 2025 Aug 5;10(30):32895-32906
A Novel pH-Responsive Baicalein@Chitosan Hydrogel for the Topical Treatment of Herpes Simplex Virus Type 1 Skin Infections: Therapeutic Potential and Mechanisms.
Lu Y, Zhou L, Ouyang A, Wang X, Wei X, Xing S, Nong F, Lin J, Wang H, Li Y, Deng J, Bao Y, Yang J, Jin R, Luo Z
Advanced healthcare materials 2025 Apr;14(11):e2403961
Advanced healthcare materials 2025 Apr;14(11):e2403961
Luteolin 7-Glucuronide in Artemisia rupestris L. Extract Attenuates Pulmonary Fibrosis by Inhibiting Fibroblast Activation and FMT via Targeting of TGF-β1.
Peng L, Fan Y, Wang L, Han C, Hao Z
Antioxidants (Basel, Switzerland) 2025 Apr 29;14(5)
Antioxidants (Basel, Switzerland) 2025 Apr 29;14(5)
Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages.
Luo C, Huang C, Zhu Y, Zhou Y, Qiao Y, Shi C, Gao Y, Guo Y, Wei L
Cell death & disease 2025 Apr 11;16(1):278
Cell death & disease 2025 Apr 11;16(1):278
Knockout of C1q/tumor necrosis factor-related protein-9 aggravates cardiac fibrosis in diabetic mice by regulating YAP-mediated autophagy.
Ruan S, Li J, Lei S, Zhang S, Xu D, Zuo A, Li L, Guo Y
Frontiers in pharmacology 2024;15:1407883
Frontiers in pharmacology 2024;15:1407883
Adipose-derived stem cells derived decellularized extracellular matrix enabled skin regeneration and remodeling.
Zhang J, Xiang Y, Yang Q, Chen J, Liu L, Jin J, Zhu S
Frontiers in bioengineering and biotechnology 2024;12:1347995
Frontiers in bioengineering and biotechnology 2024;12:1347995
Omaveloxolone ameliorates glucocorticoid-induced osteonecrosis of the femoral head by promoting osteogenesis and angiogenesis.
Wan C, Liang C, Peng H
Biochemical and biophysical research communications 2024 Sep 3;723:150188
Biochemical and biophysical research communications 2024 Sep 3;723:150188
Copper ion-doped multifunctional hydrogel with mild photothermal enhancement promotes vascularized bone regeneration.
Han C, Lu D, Yang S, Liu C, Guo F, Zhang K, Li P
Journal of biomaterials applications 2024 Oct;39(4):332-342
Journal of biomaterials applications 2024 Oct;39(4):332-342
Targeting Bacteria-Induced Ferroptosis of Bone Marrow Mesenchymal Stem Cells to Promote the Repair of Infected Bone Defects.
Yuan K, Yang Y, Lin Y, Zhou F, Huang K, Yang S, Kong W, Li F, Kan T, Wang Y, Cheng C, Liang Y, Chang H, Huang J, Ao H, Yu Z, Li H, Liu Y, Tang T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2404453
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2404453
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis.
Zhang Y, Wu R, Zhan X, Wang XY, Xiang LW, Duan YQ, You Y, Zhang JB, Wu R, Zhang YY, Duan L
Cell communication and signaling : CCS 2024 Nov 20;22(1):556
Cell communication and signaling : CCS 2024 Nov 20;22(1):556
Exogenous PRAS40 reduces KLF4 expression and alleviates hypertrophic scar fibrosis and collagen deposition through inhibiting mTORC1.
Wang C, Jiang D
Burns : journal of the International Society for Burn Injuries 2024 May;50(4):936-946
Burns : journal of the International Society for Burn Injuries 2024 May;50(4):936-946
Empagliflozin attenuates liver fibrosis in high-fat diet/streptozotocin-induced mice by modulating gut microbiota.
Huang C, Qian J, Liu Y, Zhang L, Yang Y
Clinical and experimental pharmacology & physiology 2024 Mar;51(3):e13842
Clinical and experimental pharmacology & physiology 2024 Mar;51(3):e13842
The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl(4)-caused murine liver fibrosis in vivo.
Liu B, Xie X, Yang X, Dou C, Tang H, Liu J
Human cell 2024 Mar;37(2):435-450
Human cell 2024 Mar;37(2):435-450
LncRNA Snhg12/IGFBP3 axis is involved in liver fibrosis by promoting the proliferation and activation of mouse hepatic stellate cells.
Liao J, Yuan Q, Luo L, Hu X, Li Z, Zhang Z
Journal of cell communication and signaling 2024 Jun;18(2):e12033
Journal of cell communication and signaling 2024 Jun;18(2):e12033
Carnosol attenuates angiotensin II-induced cardiac remodeling and inflammation via directly binding to p38 and inhibiting p38 activation.
Xu D, Ye B, Lin L, Jin Y, Jiang Y, Zheng Z, Chen Y, Han X, Wang W, Wu G, Zhuang Z, Shan P, Liang G
International immunopharmacology 2024 Jun 15;134:112143
International immunopharmacology 2024 Jun 15;134:112143
LDHA contributes to nicotine induced cardiac fibrosis through autophagy flux impairment.
Wu HH, Du JM, Liu P, Meng FL, Li YY, Li WJ, Wang SX, Du NL, Zheng Y, Zhang L, Wang HY, Liu YR, Song CH, Ni X, Li Y, Su GH
International immunopharmacology 2024 Jul 30;136:112338
International immunopharmacology 2024 Jul 30;136:112338
MBNL2 promotes aging-related cardiac fibrosis via inhibited SUMOylation of Krüppel-like factor4.
Lu J, Zhao Q, Wang L, Li J, Wang H, Lv L, Yuan M, Chen Q, Zhang Z, Luo D, Sheng S, Yuan K, Liu G, Liu M, Shi Y, Guo Y, Dong Z
iScience 2024 Jul 19;27(7):110163
iScience 2024 Jul 19;27(7):110163
3D-printed tri-element-doped hydroxyapatite/ polycaprolactone composite scaffolds with antibacterial potential for osteosarcoma therapy and bone regeneration.
Huang H, Qiang L, Fan M, Liu Y, Yang A, Chang D, Li J, Sun T, Wang Y, Guo R, Zhuang H, Li X, Guo T, Wang J, Tan H, Zheng P, Weng J
Bioactive materials 2024 Jan;31:18-37
Bioactive materials 2024 Jan;31:18-37
Recombinant Slit2 attenuates tracheal fibroblast activation in benign central airway obstruction by inhibiting the TGF-β1/Smad3 signaling pathway.
He C, Gu L, Li A, Li Y, Xiao R, Liao J, Mu J, Gan Y, Peng M, Mohan G, Liu W, Xu L, Guo S
Molecular and cellular probes 2024 Feb;73:101947
Molecular and cellular probes 2024 Feb;73:101947
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
Jiang B, Xiao S, Zhang S, Xiao F
Journal of ovarian research 2024 Feb 24;17(1):52
Journal of ovarian research 2024 Feb 24;17(1):52
Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway.
Qian C, Xu D, Wang J, Luo Y, Jin T, Huang L, Zhou Y, Cai Z, Jin B, Bao H, Wang Y
International immunopharmacology 2024 Feb 15;128:111551
International immunopharmacology 2024 Feb 15;128:111551
Aristolochic acid I promotes renal tubulointerstitial fibrosis by up-regulating expression of indoleamine 2,3-dioxygenase-1 (IDO1).
Chen L, Cheng S, Ying J, Zhang Q, Wang C, Wu H, Wang Y, Zhang H, Wang J, Ye J, Zhang L
Toxicology letters 2024 Dec;402:44-55
Toxicology letters 2024 Dec;402:44-55
Matrix vesicles from osteoblasts promote atherosclerotic calcification.
Wang X, Ren J, Fang F, Wang E, Li J, He W, Zhang Z, Shen Y, Liu X
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
Matrix biology : journal of the International Society for Matrix Biology 2024 Dec;134:79-92
Discoidin Domain Receptor 2 Contributes to Breast Cancer Progression and Chemoresistance by Interacting with Collagen Type I.
Sato A, Takagi K, Yoshida M, Yamaguchi-Tanaka M, Sagehashi M, Miki Y, Miyashita M, Suzuki T
Cancers 2024 Dec 23;16(24)
Cancers 2024 Dec 23;16(24)
The hematopoietic activity of EPO is unfavorable to the treatment of bleomycin-induced pulmonary fibrosis in mice.
Wu P, Zhang W, Zuo X, Liu S, Jin T, Jia J, Luo B, Wang G, Zhang Z
Biochemical and biophysical research communications 2024 Dec 20;739:150951
Biochemical and biophysical research communications 2024 Dec 20;739:150951
VDR regulates mitochondrial function as a protective mechanism against renal tubular cell injury in diabetic rats.
Chen H, Zhang H, Li AM, Liu YT, Liu Y, Zhang W, Yang C, Song N, Zhan M, Yang S
Redox biology 2024 Apr;70:103062
Redox biology 2024 Apr;70:103062
Phytic acid promotes high glucose-mediated bone marrow mesenchymal stem cells osteogenesis via modulating circEIF4B that sponges miR-186-5p and complexes with IGF2BP3.
Wu J, Li X, Nie H, Shen Y, Guo Z, Huihan Chu C, Cai K, Tang C
Biochemical pharmacology 2024 Apr;222:116118
Biochemical pharmacology 2024 Apr;222:116118
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Zhang Y, Lu YB, Zhu WJ, Gong XX, Qian R, Lu YJ, Li Y, Yao WF, Bao BH, Zhang Y, Zhang L, Cheng FF
Journal of ethnopharmacology 2024 Apr 24;324:117737
Journal of ethnopharmacology 2024 Apr 24;324:117737
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate renal fibrosis in diabetic nephropathy by targeting Hedgehog/SMO signaling.
Zhang K, Zheng S, Wu J, He J, Ouyang Y, Ao C, Lang R, Jiang Y, Yang Y, Xiao H, Li Y, Li M, Wang H, Li C, Wu D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23599
Drug repurposing screens to identify potential drugs for chronic kidney disease by targeting prostaglandin E2 receptor.
Huang HJ, Lee YH, Sung LC, Chen YJ, Chiu YJ, Chiu HW, Zheng CM
Computational and structural biotechnology journal 2023;21:3490-3502
Computational and structural biotechnology journal 2023;21:3490-3502
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Asarinin attenuates bleomycin-induced pulmonary fibrosis by activating PPARγ.
Zeng Q, Zhou TT, Huang WJ, Huang XT, Huang L, Zhang XH, Sang XX, Luo YY, Tian YM, Wu B, Liu L, Luo ZQ, He B, Liu W, Tang SY
Scientific reports 2023 Sep 7;13(1):14706
Scientific reports 2023 Sep 7;13(1):14706
β-elemene alleviates hyperglycemia-induced cardiac inflammation and remodeling by inhibiting the JAK/STAT3-NF-κB pathway.
Wang J, Qian C, Chen Y, Jin T, Jiang Y, Huang L, Fu X, Yang D, Jin L, Jin B, Wang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154987
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Oct;119:154987
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
RhoA vesicle trafficking-mediated transglutaminase 2 membrane translocation promotes IgA1 mesangial deposition in IgA nephropathy.
Zhong Z, Li Z, Li Y, Jiang L, Kong Q, Chen W, Feng S
JCI insight 2023 Oct 9;8(19)
JCI insight 2023 Oct 9;8(19)
Tobacco toxins induce osteoporosis through ferroptosis.
Jing Z, Li Y, Zhang H, Chen T, Yu J, Xu X, Zou Y, Wang X, Xiang K, Gong X, He P, Fu Y, Ren M, Ji P, Yang S
Redox biology 2023 Nov;67:102922
Redox biology 2023 Nov;67:102922
Costunolide alleviates hyperglycaemia-induced diabetic cardiomyopathy via inhibiting inflammatory responses and oxidative stress.
Jin B, Chen Y, Wang J, Chen Y, Zhang M, Huang J, Wang Y
Journal of cellular and molecular medicine 2023 Mar;27(6):831-845
Journal of cellular and molecular medicine 2023 Mar;27(6):831-845
3D-printed hydrogel particles containing PRP laden with TDSCs promote tendon repair in a rat model of tendinopathy.
Li C, Wang J, Yang W, Yu K, Hong J, Ji X, Yao M, Li S, Lu J, Chen Y, Yan S, Wu H, Ma C, Yu X, Jiang G, Liu A
Journal of nanobiotechnology 2023 Jun 3;21(1):177
Journal of nanobiotechnology 2023 Jun 3;21(1):177
[Lipopolysaccharide stimulates macrophages to secrete exosomes containing miR-155-5p to promote activation and migration of hepatic stellate cells].
Lin J, Lou A, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):994-1001
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):994-1001
Focal adhesion kinase induces cardiac remodeling through NF-κB-mediated inflammatory responses in diabetic cardiomyopathy.
Jin B, Wang J, Chen Y, Zuo W, Hong B, Li J, Huang F, Zhang M, Wang Y
International immunopharmacology 2023 Jul;120:110280
International immunopharmacology 2023 Jul;120:110280
Experimental Design of Vertical Distraction Osteogenesis Using Simple 3 Screws.
Li Z, Jiang D, Yao Y
The Journal of craniofacial surgery 2023 Jul-Aug 01;34(5):1599-1604
The Journal of craniofacial surgery 2023 Jul-Aug 01;34(5):1599-1604
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Huang K, Wu H, Xu X, Wu L, Li Q, Han L
Aging 2023 Jul 26;15(14):7187-7218
Aging 2023 Jul 26;15(14):7187-7218
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
Li RJ, Wu CY, Ke HL, Wang XP, Zhang YW
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
Facile preparation of a novel nanoemulsion based hyaluronic acid hydrogel loading with Poria cocos triterpenoids extract for wound dressing.
Ding X, Li S, Tian M, Yang P, Ding Y, Wang Y, Duan G, Zhang D, Chen B, Tan Q
International journal of biological macromolecules 2023 Jan 31;226:1490-1499
International journal of biological macromolecules 2023 Jan 31;226:1490-1499
Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca2+ mishandling and atrial fibrosis in active immunization rabbit models.
Sun H, Song J, Li K, Li Y, Shang L, Zhou Q, Lu Y, Zong Y, He X, Kari M, Yang H, Zhou X, Zhang L, Tang B
Clinical science (London, England : 1979) 2023 Jan 31;137(2):195-217
Clinical science (London, England : 1979) 2023 Jan 31;137(2):195-217
Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis.
Zhang MH, Han XX, Lu Y, Deng JJ, Zhang WH, Mao JQ, Mi J, Ding WH, Wu MJ, Yu LM, Liu YH
Respiratory physiology & neurobiology 2023 Feb;308:103980
Respiratory physiology & neurobiology 2023 Feb;308:103980
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Chen C, Chen Y, Lan YJ, Tian MN, Zhang YM, Lei ZY, Fan DL
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Albumin-Based Silibinin Nanocrystals Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy.
Luo S, Yang Y, Zhao T, Zhang R, Fang C, Li Y, Zhang Z, Gong T
ACS applied materials & interfaces 2023 Feb 15;15(6):7747-7758
ACS applied materials & interfaces 2023 Feb 15;15(6):7747-7758
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
Exploring the Role of Lycium barbarum Polysaccharide in Corneal Injury Repair and Investigating the Relevant Mechanisms through In Vivo and In Vitro Experiments.
Liu Q, Nan Y, Yang Y, Li X, Jiang W, Jiao T, Li J, Jia X, Ye M, Niu Y, Yuan L
Molecules (Basel, Switzerland) 2023 Dec 20;29(1)
Molecules (Basel, Switzerland) 2023 Dec 20;29(1)
miR-146a-5p Alleviates Radiation-Induced Liver Fibrosis by Regulating PTPRA-SRC Signaling in Mice.
Yuan BY, Zhuang Y, Wu ZF, Zhao XM, Zhang L, Chen GW, Zeng ZC
Radiation research 2023 Dec 1;200(6):531-537
Radiation research 2023 Dec 1;200(6):531-537
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats.
Wang M, Zhao M, Xu S, Zheng Z, Zhang J, Pan W, Yin Z, Liu J, Wei C, Wan J, Xu Y
Biochemical pharmacology 2023 Aug;214:115671
Biochemical pharmacology 2023 Aug;214:115671
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
Ni WJ, Zhou H, Lu H, Ma NN, Hou BB, Li W, Kong FX, Yu JT, Hou R, Jin J, Wen JG, Zhang T, Meng XM
Clinical and translational medicine 2023 Aug;13(8):e1359
Clinical and translational medicine 2023 Aug;13(8):e1359
NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways.
Meng L, Lu Y, Wang X, Cheng C, Xue F, Xie L, Zhang Y, Sui W, Zhang M, Zhang Y, Zhang C
Science advances 2023 Aug 2;9(31):eadd4222
Science advances 2023 Aug 2;9(31):eadd4222
Nitration of cAMP-Response Element Binding Protein Participates in Myocardial Infarction-Induced Myocardial Fibrosis via Accelerating Transcription of Col1a2 and Cxcl12.
Xue K, Chen S, Chai J, Yan W, Zhu X, Ji D, Wu Y, Liu H, Wang W
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Antioxidants & redox signaling 2023 Apr;38(10-12):709-730
Photothermal lipolysis accelerates ECM production via macrophage-derived ALOX15-mediated p38 MAPK activation in fibroblasts.
Wu S, Wang C, Yao M, Han D, Li Q
Journal of biophotonics 2023 Apr;16(4):e202200321
Journal of biophotonics 2023 Apr;16(4):e202200321
A sustained release of BMP2 in urine-derived stem cells enhances the osteogenic differentiation and the potential of bone regeneration.
Wu S, Chen Z, Yu X, Duan X, Chen J, Liu G, Gong M, Xing F, Sun J, Huang S, Xiang Z
Regenerative biomaterials 2022;9:rbac015
Regenerative biomaterials 2022;9:rbac015
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Zhang Y, Wang D, Wu K, Shao X, Diao H, Wang Z, Sun M, Huang X, Li Y, Tang X, Yan M, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension.
Tang Y, Huo X, Liu J, Tang Y, Zhang M, Xie W, Zheng Z, He J, Lian J
Cardiovascular therapeutics 2022;2022:4382999
Cardiovascular therapeutics 2022;2022:4382999
Eugenol-Preconditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Antioxidant Capacity of Tendon Stem Cells In Vitro and In Vivo.
Li X, Su Z, Shen K, Wang Q, Xu C, Wang F, Zhang Y, Jiang D
Oxidative medicine and cellular longevity 2022;2022:3945195
Oxidative medicine and cellular longevity 2022;2022:3945195
Ginsenoside Rb1 Alleviates Bleomycin-Induced Pulmonary Inflammation and Fibrosis by Suppressing Central Nucleotide-Binding Oligomerization-, Leucine-Rich Repeat-, and Pyrin Domains-Containing Protein Three Inflammasome Activation and the NF-κB Pathway.
Liu J, Fan G, Tao N, Feng F, Meng C, Sun T
Drug design, development and therapy 2022;16:1793-1809
Drug design, development and therapy 2022;16:1793-1809
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Li Z, Geng J, Xie B, He J, Wang J, Peng L, Hu Y, Dai H, Wang C
Frontiers in pharmacology 2022;13:834604
Frontiers in pharmacology 2022;13:834604
Erratum: Addendum: A novel N-Arylpyridone compound alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 pathway and regulating macrophage polarization.
Fan M, Xiao H, Song D, Zhu L, Zhang J, Zhang X, Wang J, Dai H, Wang C
Frontiers in pharmacology 2022;13:1108989
Frontiers in pharmacology 2022;13:1108989
Multitranscriptome analyses of keloid fibroblasts reveal the role of the HIF-1α/HOXC6/ERK axis in keloid development.
Wang Q, Zhong Y, Li Z, Zhu D, Lu H, Chen P, Li C, Peng X, Li Q, Zeng K
Burns & trauma 2022;10:tkac013
Burns & trauma 2022;10:tkac013
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Zhu H, Liu H, Chen X, Xu X, Zhang S, Xie D
Frontiers in cell and developmental biology 2022;10:971736
Frontiers in cell and developmental biology 2022;10:971736
Primary Repair for Treating Acute Proximal Anterior Cruciate Ligament Tears: A Histological Analysis and Prospective Clinical Trial.
Yang Y, Jin Z, Luo J, Zhang D, Shen P, Zheng D, Liu D, Bai L
Frontiers in bioengineering and biotechnology 2022;10:913900
Frontiers in bioengineering and biotechnology 2022;10:913900
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Liu Y, Kong X, You Y, Xiang L, Zhang Y, Wu R, Zhou L, Duan L
Cells 2022 Nov 12;11(22)
Cells 2022 Nov 12;11(22)
Loss of RTN3 phenocopies chronic kidney disease and results in activation of the IGF2-JAK2 pathway in proximal tubular epithelial cells.
Fan LL, Du R, Liu JS, Jin JY, Wang CY, Dong Y, He WX, Yan RQ, Xiang R
Experimental & molecular medicine 2022 May;54(5):653-661
Experimental & molecular medicine 2022 May;54(5):653-661
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1.
Luo P, Liu D, Zhang Q, Yang F, Wong YK, Xia F, Zhang J, Chen J, Tian Y, Yang C, Dai L, Shen HM, Wang J
Acta pharmaceutica Sinica. B 2022 May;12(5):2300-2314
Acta pharmaceutica Sinica. B 2022 May;12(5):2300-2314
Ginsenoside Rc Promotes Bone Formation in Ovariectomy-Induced Osteoporosis In Vivo and Osteogenic Differentiation In Vitro.
Yang N, Zhang X, Li L, Xu T, Li M, Zhao Q, Yu J, Wang J, Liu Z
International journal of molecular sciences 2022 May 31;23(11)
International journal of molecular sciences 2022 May 31;23(11)
Upregulation of Periostin Through CREB Participates in Myocardial Infarction-induced Myocardial Fibrosis.
Xue K, Chen S, Chai J, Yan W, Zhu X, Dai H, Wang W
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Journal of cardiovascular pharmacology 2022 May 1;79(5):687-697
Optimization of the saffron compound essence formula and its effect on preventing skin photoaging.
Li Q, Liu L, Jiang S, Xu Z, Lin S, Tong Y, Wang P
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
Journal of cosmetic dermatology 2022 Mar;21(3):1251-1262
Overexpression of G Protein-Coupled Receptor 40 Protects Obesity-Induced Cardiomyopathy Through the SIRT1/LKB1/AMPK Pathway.
Li SN, Yu YL, Wang BY, Qiao SY, Hu MM, Wang H, Fu CN, Dong B
Human gene therapy 2022 Jun;33(11-12):598-613
Human gene therapy 2022 Jun;33(11-12):598-613
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.
Guan S, Liu H, Zhou J, Zhang Q, Bi H
Toxicology letters 2022 Jun 15;363:45-54
Toxicology letters 2022 Jun 15;363:45-54
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl(4)-caused liver fibrosis.
Liao J, Zhang Z, Yuan Q, Luo L, Hu X
Toxicology letters 2022 Jun 1;362:38-49
Toxicology letters 2022 Jun 1;362:38-49
Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.
Chang P, Li S, Sun Q, Guo K, Wang H, Li S, Zhang L, Xie Y, Zheng X, Liu Y
Macromolecular bioscience 2022 Feb;22(2):e2100403
Macromolecular bioscience 2022 Feb;22(2):e2100403
Zanubrutinib attenuates bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β1 signaling pathway.
Chen S, Wei Y, Li S, Miao Y, Gu J, Cui Y, Liu Z, Liang J, Wei L, Li X, Zhou H, Yang C
International immunopharmacology 2022 Dec;113(Pt A):109316
International immunopharmacology 2022 Dec;113(Pt A):109316
Evaluation of HZX-960, a novel DCN1-UBC12 interaction inhibitor, as a potential antifibrotic compound for liver fibrosis.
Zhou W, Dong G, Gao G, He Z, Xu J, Aziz S, Ma L, Zhao W
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Aug 1;100(4):309-324
Biochemistry and cell biology = Biochimie et biologie cellulaire 2022 Aug 1;100(4):309-324
Immunohistochemical expression of osteopontin and collagens in choroid plexus of human brains.
Wakamatsu K, Chiba Y, Murakami R, Matsumoto K, Miyai Y, Kawauchi M, Yanase K, Uemura N, Ueno M
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Apr;42(2):117-125
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
Qi X, Luo B, Deng M, Cao J, Hou S, Xie Z, Tong B, Xiong W
Experimental eye research 2022 Apr;217:108971
Experimental eye research 2022 Apr;217:108971
GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro.
Speca S, Dubuquoy C, Rousseaux C, Chavatte P, Desreumaux P, Spagnolo P
PloS one 2021;16(9):e0257281
PloS one 2021;16(9):e0257281
miR-506-3p regulates TGF- 1 and affects dermal fibroblast proliferation, migration and collagen formation after thermal injury.
Yang M, Yang Z, Pan X, Huang X, Yang L, Xue Y
Tissue & cell 2021 Oct;72:101548
Tissue & cell 2021 Oct;72:101548
Ppic modulates CCl(4)-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.
Yang X, Shu B, Zhou Y, Li Z, He C
Toxicology letters 2021 Oct 10;350:52-61
Toxicology letters 2021 Oct 10;350:52-61
Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats.
Li Z, Lu D, Jin T, Liu X, Hao J
Toxicology letters 2021 Oct 1;349:84-91
Toxicology letters 2021 Oct 1;349:84-91
MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.
Xie X, Dou CY, Zhou Y, Zhou Q, Tang HB
Digestive diseases and sciences 2021 Jun;66(6):1928-1939
Digestive diseases and sciences 2021 Jun;66(6):1928-1939
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Miao Z, Ding Y, Bi Y, Chen M, Cao X, Wang F
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2021 Jun;54(3):411-419
Metformin Carbon Dots for Promoting Periodontal Bone Regeneration via Activation of ERK/AMPK Pathway.
Ren C, Hao X, Wang L, Hu Y, Meng L, Zheng S, Ren F, Bu W, Wang H, Li D, Zhang K, Sun H
Advanced healthcare materials 2021 Jun;10(12):e2100196
Advanced healthcare materials 2021 Jun;10(12):e2100196
Silencing Proteasome 26S Subunit ATPase 2 (PSMC2) Protects the Osteogenic Differentiation In Vitro and Osteogenesis In Vivo.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Calcified tissue international 2021 Jul;109(1):44-54
Calcified tissue international 2021 Jul;109(1):44-54
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151
International immunopharmacology 2021 Jan;90:107151
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.
Liao J, Zhang Z, Yuan Q, Liu Q, Kuang J, Fang Y, Hu X
Toxicology letters 2021 Jan 1;336:21-31
Toxicology letters 2021 Jan 1;336:21-31
Polo Like Kinase 4 (PLK4) impairs human bone marrow mesenchymal stem cell (BMSC) viability and osteogenic differentiation.
Zhou B, Peng K, Wang G, Chen W, Kang Y
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Biochemical and biophysical research communications 2021 Apr 16;549:221-228
Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.
Zhou J, Zhang X, Wan L, Yu J, Li T, Lu Z, Fang N, Sun L, Ye F
Medical science monitor : international medical journal of experimental and clinical research 2021 Apr 14;27:e929438
Medical science monitor : international medical journal of experimental and clinical research 2021 Apr 14;27:e929438
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma.
Li Y, Chen R, Yang J, Mo S, Quek K, Kok CH, Cheng XD, Tian S, Zhang W, Qin JJ
Frontiers in genetics 2020;11:814
Frontiers in genetics 2020;11:814
The AKT inhibitor MK2206 suppresses airway inflammation and the pro‑remodeling pathway in a TDI‑induced asthma mouse model.
Cui H, Cheng Y, He Y, Cheng W, Zhao W, Zhao H, Zhou FH, Wang L, Dong J, Cai S
Molecular medicine reports 2020 Nov;22(5):3723-3734
Molecular medicine reports 2020 Nov;22(5):3723-3734
Adipose‑derived mesenchymal stem cells ameliorate dibutyltin dichloride‑induced chronic pancreatitis by inhibiting the PI3K/AKT/mTOR signaling pathway.
Xu X, Yu H, Sun L, Zheng C, Shan Y, Zhou Z, Wang C, Chen B
Molecular medicine reports 2020 Apr;21(4):1833-1840
Molecular medicine reports 2020 Apr;21(4):1833-1840
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