Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16623-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16623-1-AP, RRID:AB_10666165
- Product name
- ACADS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ACADS antibody (Cat. #16623-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Artemether regulates liver glycogen and lipid utilization through mitochondrial pyruvate oxidation in db/db mice.
Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity.
YBX1 as a prognostic biomarker and potential therapeutic target in hepatocellular carcinoma: A comprehensive investigation through bioinformatics analysis and in vitro study.
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Comparison of the stage-dependent mitochondrial changes in response to pressure overload between the diseased right and left ventricle in the rat.
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Dietary iron overload mitigates atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice: Role of dysregulated hepatic fatty acid metabolism.
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
ACADS acts as a potential methylation biomarker associated with the proliferation and metastasis of hepatocellular carcinomas.
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
Potent effects of dioscin against obesity in mice.
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Protective effects of dioscin against alcohol-induced liver injury.
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Weng W, Shen L, Yu X, Yuan R, Shao M, Han P, Sun H
American journal of translational research 2024;16(1):27-38
American journal of translational research 2024;16(1):27-38
Targeting Erbin-mitochondria axis in platelets/megakaryocytes promotes B cell-mediated antitumor immunity.
Zhang Z, Xu X, Zhang D, Zhao S, Wang C, Zhang G, Chen W, Liu J, Gong H, Rixiati Y, Li S, Shen T, Li J
Cell metabolism 2024 Mar 5;36(3):541-556.e9
Cell metabolism 2024 Mar 5;36(3):541-556.e9
YBX1 as a prognostic biomarker and potential therapeutic target in hepatocellular carcinoma: A comprehensive investigation through bioinformatics analysis and in vitro study.
Li Z, Lu W, Yin F, Huang A
Translational oncology 2024 Jul;45:101965
Translational oncology 2024 Jul;45:101965
Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation.
Mao Y, Zhang J, Zhou Q, He X, Zheng Z, Wei Y, Zhou K, Lin Y, Yu H, Zhang H, Zhou Y, Lin P, Wu B, Yuan Y, Zhao J, Xu W, Zhao S
Cell research 2024 Jan;34(1):13-30
Cell research 2024 Jan;34(1):13-30
Comparison of the stage-dependent mitochondrial changes in response to pressure overload between the diseased right and left ventricle in the rat.
Li L, Niemann B, Knapp F, Werner S, Mühlfeld C, Schneider JP, Jurida LM, Molenda N, Schmitz ML, Yin X, Mayr M, Schulz R, Kracht M, Rohrbach S
Basic research in cardiology 2024 Aug;119(4):587-611
Basic research in cardiology 2024 Aug;119(4):587-611
Riboflavin ameliorates pathological cardiac hypertrophy and fibrosis through the activation of short-chain acyl-CoA dehydrogenase.
Peng H, Xie M, Zhong X, Su Y, Qin X, Xu Q, Zhou S
European journal of pharmacology 2023 Sep 5;954:175849
European journal of pharmacology 2023 Sep 5;954:175849
Short-chain acyl-CoA dehydrogenase is a potential target for the treatment of vascular remodelling.
Zhong X, Li Z, Xu Q, Peng H, Su Y, Le K, Shu Z, Liao Y, Ma Z, Pan X, Xu S, Zhou S
Journal of hypertension 2023 May 1;41(5):775-793
Journal of hypertension 2023 May 1;41(5):775-793
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
Xu Q, Cao Y, Zhong X, Qin X, Feng J, Peng H, Su Y, Ma Z, Zhou S
British journal of pharmacology 2023 Dec;180(23):3024-3044
British journal of pharmacology 2023 Dec;180(23):3024-3044
Dietary iron overload mitigates atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice: Role of dysregulated hepatic fatty acid metabolism.
Xiao L, Luo G, Li H, Yao P, Tang Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Oct;1866(10):159004
Biochimica et biophysica acta. Molecular and cell biology of lipids 2021 Oct;1866(10):159004
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function.
Thapa D, Manning JR, Mushala BAS, Stoner MW, Zhang M, Scott I
Current research in physiology 2020 Dec;3:44-49
Current research in physiology 2020 Dec;3:44-49
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
ACADS acts as a potential methylation biomarker associated with the proliferation and metastasis of hepatocellular carcinomas.
Chen D, Feng X, Lv Z, Xu X, Lu Y, Wu W, Wu H, Liu H, Cao L, Ye S, Chen J, Wu J
Aging 2019 Oct 25;11(20):8825-8844
Aging 2019 Oct 25;11(20):8825-8844
Correction: Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2019 Aug 1;10(8):5240-5241
Food & function 2019 Aug 1;10(8):5240-5241
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
Thapa D, Zhang M, Manning JR, Guimarães DA, Stoner MW, O'Doherty RM, Shiva S, Scott I
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H265-H274
American journal of physiology. Heart and circulatory physiology 2017 Aug 1;313(2):H265-H274
Potent effects of dioscin against obesity in mice.
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, Zhao Y, Sun H, Yao J, Lin Y, Liu K, Peng J
Scientific reports 2015 Jan 22;5:7973
Scientific reports 2015 Jan 22;5:7973
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Huang D, Li T, Li X, Zhang L, Sun L, He X, Zhong X, Jia D, Song L, Semenza GL, Gao P, Zhang H
Cell reports 2014 Sep 25;8(6):1930-1942
Cell reports 2014 Sep 25;8(6):1930-1942
Protective effects of dioscin against alcohol-induced liver injury.
Xu T, Zheng L, Xu L, Yin L, Qi Y, Xu Y, Han X, Peng J
Archives of toxicology 2014 Mar;88(3):739-53
Archives of toxicology 2014 Mar;88(3):739-53
Total saponins from Rosa laevigata Michx fruit attenuates hepatic steatosis induced by high-fat diet in rats.
Dong D, Qi Y, Xu L, Yin L, Xu Y, Han X, Zhao Y, Peng J
Food & function 2014 Dec;5(12):3065-3075
Food & function 2014 Dec;5(12):3065-3075
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16623-1-AP(ACADS antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 16623-1-AP(ACADS antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACADS antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ACADS. This antibody recognizes human,mouse,rat, monkey antigen. The ACADS antibody has been validated for the following applications: ELISA, WB, IHC analysis.