Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS2668 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- DPF2 (E174) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 140-188 of Human DPF2.
- Description
- DPF2 (D4, zinc and double PHD fingers family 2), also known as REQ (Requiem), UBID4 or ubi-d4, is a 391 amino acid protein that is a member of the D4 domain family. DPF2, a ubiquitously expressed protein, localizes to the nucleus and contains one C2H2- and two PHD-type zinc finger motifs. DPF2 may function as a transcription factor that is necessary for apoptosis and may also play a role in the development and maturation of lymphoid cells. It is thought that, during apoptosis, DPF2 activity is inhibited by LRF (Leukemia/lymphoma-related factor), which is upregulated by integrin. This suggests that DPF2 may be a potential target for future cancer therapies that induce apoptosis in leukemia cells. Alternative splicing of this gene generates multiple isoforms lacking certain domain.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of DPF2 (E174) pAb at 1:1000 dilution Lane1:THP-1 whole cell lysate(37ug) Lane2:MCF-7 whole cell lysate(48ug) Lane3:RAW264.7 whole cell lysate(57ug) Lane4:NIH3T3 whole cell lysate(48ug) Lane5:H9C2 whole cell lysate(37ug)