CABT-L2020

antibody from Creative Diagnostics

Targeting: IDH2

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-L2020

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human IDH2 Polyclonal Antibody

Antibody type

Polyclonal

Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Reactivity

Human, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

200 _g

Concentration

Lot specific

Storage

Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.