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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 11604-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11604-1-AP, RRID:AB_2258046
- Product name
- ALDH4A1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ALDH4A1 antibody (Cat. #11604-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Impaired xCT-mediated cystine uptake drives serine and proline metabolic reprogramming and mitochondrial fission in skeletal muscle cells.
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons.
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure.
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
Kanaan MN, Karam CY, Kennedy LS, Pileggi CA, Hamilton L, Cuperlovic-Culf M, Harper ME
Redox biology 2025 Oct;86:103839
Redox biology 2025 Oct;86:103839
Noninvasive Optogenetics Realized by iPSC-Derived Tentacled Carrier in Alzheimer's Disease Treatment.
Zhai Y, Gao F, Shi S, Zhong Q, Zhang J, Fang J, He F, Zhang Y, Li Y, Liu F, Xue B, Gu Y, Li S
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Advanced materials (Deerfield Beach, Fla.) 2025 Aug;37(32):e2419768
Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons.
Pardo E, Kim T, Wallrabe H, Zengeler KE, Sagar VK, Mingledorff G, Sun X, Periasamy A, Lukens JR, Bloom GS, Norambuena A
bioRxiv : the preprint server for biology 2024 Nov 1;
bioRxiv : the preprint server for biology 2024 Nov 1;
Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells.
Linder SJ, Bernasocchi T, MartÃnez-Pastor B, Sullivan KD, Galbraith MD, Lewis CA, Ferrer CM, Boon R, Silveira GG, Cho HM, Vidoudez C, Shroff S, Oliveira-Costa JP, Ross KN, Massri R, Matoba Y, Kim E, Rueda BR, Stott SL, Gottlieb E, Espinosa JM, Mostoslavsky R
Nature metabolism 2023 Dec;5(12):2131-2147
Nature metabolism 2023 Dec;5(12):2131-2147
Pharmacological targeting PTK6 inhibits the JAK2/STAT3 sustained stemness and reverses chemoresistance of colorectal cancer.
Liu C, Pan Z, Chen Q, Chen Z, Liu W, Wu L, Jiang M, Lin W, Zhang Y, Lin W, Zhou R, Zhao L
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Journal of experimental & clinical cancer research : CR 2021 Sep 22;40(1):297
Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure.
Jones B, Balasubramaniam M, Lebowitz JJ, Taylor A, Villalta F, Khoshbouei H, Grueter C, Grueter B, Dash C, Pandhare J
Scientific reports 2021 Jan 14;11(1):1422
Scientific reports 2021 Jan 14;11(1):1422
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
Liu W, Le A, Hancock C, Lane AN, Dang CV, Fan TW, Phang JM
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 5;109(23):8983-8
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 5;109(23):8983-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 11604-1-AP(ALDH4A1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 11604-1-AP(ALDH4A1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALDH4A1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ALDH4A1. This antibody recognizes human,mouse,rat antigen. The ALDH4A1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
