Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16135-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16135-1-AP, RRID:AB_2210480
- Product name
- UBXN1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBXN1 antibody (Cat. #16135-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Allelic heterogeneity and abnormal vesicle recycling in PLAA-related neurodevelopmental disorders.
SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1.
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
p53 promotes antiviral innate immunity by driving hexosamine metabolism.
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
The p97-UBXN1 complex regulates aggresome formation.
UBXN1 interacts with the S1 protein of transmissible gastroenteritis coronavirus and plays a role in viral replication.
Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1.
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
The CRISPR/Cas9 system targeting EGFR exon 17 abrogates NF-κB activation via epigenetic modulation of UBXN1 in EGFRwt/vIII glioma cells.
Iacomino M, Houerbi N, Fortuna S, Howe J, Li S, Scorrano G, Riva A, Cheng KW, Steiman M, Peltekova I, Yusuf A, Baldassari S, Tamburro S, Scudieri P, Musante I, Di Ludovico A, Guerrisi S, Balagura G, Corsello A, Efthymiou S, Murphy D, Uva P, Verrotti A, Fiorillo C, Delvecchio M, Accogli A, Elsabbagh M, Houlden H, Scherer SW, Striano P, Zara F, Chou TF, Salpietro V
Frontiers in molecular neuroscience 2024;17:1268013
Frontiers in molecular neuroscience 2024;17:1268013
SUB1 promotes colorectal cancer metastasis by activating NF-κB signaling via UBR5-mediated ubiquitination of UBXN1.
Wang H, Chen W, Wang Y, Gao Y, Zhang Z, Mi S, Wang L, Xue M
Science China. Life sciences 2024 Jun;67(6):1199-1211
Science China. Life sciences 2024 Jun;67(6):1199-1211
UBXN1 maintains ER proteostasis and represses UPR activation by modulating translation.
Ahlstedt BA, Ganji R, Mukkavalli S, Paulo JA, Gygi SP, Raman M
EMBO reports 2024 Feb;25(2):672-703
EMBO reports 2024 Feb;25(2):672-703
p53 promotes antiviral innate immunity by driving hexosamine metabolism.
Xia W, Jiang P
Cell reports 2024 Feb 27;43(2):113724
Cell reports 2024 Feb 27;43(2):113724
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M
Nature communications 2023 Feb 6;14(1):638
Nature communications 2023 Feb 6;14(1):638
PTRF/Cavin-1 as a Novel RNA-Binding Protein Expedites the NF-κB/PD-L1 Axis by Stabilizing lncRNA NEAT1, Contributing to Tumorigenesis and Immune Evasion in Glioblastoma.
Yi K, Cui X, Liu X, Wang Y, Zhao J, Yang S, Xu C, Yang E, Xiao M, Hong B, Fang C, Kang C, Tan Y, Wang Q
Frontiers in immunology 2021;12:802795
Frontiers in immunology 2021;12:802795
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
Alderson TR, Adriaenssens E, Asselbergh B, Pritišanac I, Van Lent J, Gastall HY, Wälti MA, Louis JM, Timmerman V, Baldwin AJ, Lp Benesch J
The EMBO journal 2021 Apr 15;40(8):e103811
The EMBO journal 2021 Apr 15;40(8):e103811
The p97-UBXN1 complex regulates aggresome formation.
Mukkavalli S, Klickstein JA, Ortiz B, Juo P, Raman M
Journal of cell science 2021 Apr 1;134(7)
Journal of cell science 2021 Apr 1;134(7)
UBXN1 interacts with the S1 protein of transmissible gastroenteritis coronavirus and plays a role in viral replication.
Yuan P, Huang S, Yang Z, Xie L, Wang K, Yang Y, Ran L, Yu Q, Song Z
Veterinary research 2019 Apr 27;50(1):28
Veterinary research 2019 Apr 27;50(1):28
Possible role of the Nipah virus V protein in the regulation of the interferon beta induction by interacting with UBX domain-containing protein1.
Uchida S, Horie R, Sato H, Kai C, Yoneda M
Scientific reports 2018 May 16;8(1):7682
Scientific reports 2018 May 16;8(1):7682
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)
Molecular and cellular biology 2018 Jul 1;38(13)
The CRISPR/Cas9 system targeting EGFR exon 17 abrogates NF-κB activation via epigenetic modulation of UBXN1 in EGFRwt/vIII glioma cells.
Huang K, Yang C, Wang QX, Li YS, Fang C, Tan YL, Wei JW, Wang YF, Li X, Zhou JH, Zhou BC, Yi KK, Zhang KL, Li J, Kang CS
Cancer letters 2017 Mar 1;388:269-280
Cancer letters 2017 Mar 1;388:269-280
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBXN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human UBXN1. This antibody recognizes human,mouse,rat antigen. The UBXN1 antibody has been validated for the following applications: ELISA, WB analysis.
