Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 21524-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21524-1-AP, RRID:AB_10733520
- Product name
- CCT4 antibody
- Antibody type
- Polyclonal
- Description
- CCT4 antibody (Cat. #21524-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging.
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
hsa_circ_0001018 promotes papillary thyroid cancer by facilitating cell survival, invasion, G(1)/S cell cycle progression, and repressing cell apoptosis via crosstalk with miR-338-3p and SOX4.
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT.
Lima TI, Laurila PP, Wohlwend M, Morel JD, Goeminne LJE, Li H, Romani M, Li X, Oh CM, Park D, Rodríguez-López S, Ivanisevic J, Gallart-Ayala H, Crisol B, Delort F, Batonnet-Pichon S, Silveira LR, Sankabattula Pavani Veera Venkata L, Padala AK, Jain S, Auwerx J
Science translational medicine 2023 May 17;15(696):eade6509
Science translational medicine 2023 May 17;15(696):eade6509
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Fang J, Ma Y, Li Y, Li J, Zhang X, Han X, Ma S, Guan F
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
Molecular carcinogenesis 2022 Nov;61(11):1043-1055
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Ma X, Lu C, Chen Y, Li S, Ma N, Tao X, Li Y, Wang J, Zhou M, Yan YB, Li P, Heydari K, Deng H, Zhang M, Yi C, Ge L
Cell 2022 Apr 14;185(8):1325-1345.e22
Cell 2022 Apr 14;185(8):1325-1345.e22
hsa_circ_0001018 promotes papillary thyroid cancer by facilitating cell survival, invasion, G(1)/S cell cycle progression, and repressing cell apoptosis via crosstalk with miR-338-3p and SOX4.
Luo Q, Guo F, Fu Q, Sui G
Molecular therapy. Nucleic acids 2021 Jun 4;24:591-609
Molecular therapy. Nucleic acids 2021 Jun 4;24:591-609
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
Zhang YC, Bai YF, Yuan JF, Shen XL, Xu YL, Jian XX, Li S, Song ZQ, Hu HB, Li PY, Tu HQ, Han QY, Wang N, Li AL, Zhang XM, Wu M, Zhou T, Li HY
The Journal of cell biology 2021 Feb 1;220(2)
The Journal of cell biology 2021 Feb 1;220(2)
Serum antibody response to group II chaperonin from Methanobrevibacter oralis and human chaperonin CCT.
Hirai K, Maeda H, Omori K, Yamamoto T, Kokeguchi S, Takashiba S
Pathogens and disease 2013 Jun;68(1):12-9
Pathogens and disease 2013 Jun;68(1):12-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21524-1-AP(CCT4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 21524-1-AP(CCT4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCT4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CCT4. This antibody recognizes human, mouse, rat antigen. The CCT4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.