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- References [21]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 22050-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22050-1-AP, RRID:AB_11182378
- Product name
- CEP97 antibody
- Antibody type
- Polyclonal
- Description
- CEP97 antibody (Cat. #22050-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, Canine and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Canine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dual roles of CCDC102A in governing centrosome duplication and cohesion.
Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells.
Time-series reconstruction of the molecular architecture of human centriole assembly.
INPP5E regulates CD3ζ enrichment at the immune synapse by phosphoinositide distribution control.
CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis.
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole.
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function.
Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila.
Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1.
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling.
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Centrin2 regulates CP110 removal in primary cilium formation.
Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis.
Wang T, Fan G, Xia Y, Zou Y, Liu Y, Wang J, Hu Y, Teng J, Huang N, Chen J
Cell reports 2024 Feb 27;43(2):113696
Cell reports 2024 Feb 27;43(2):113696
Mouse SAS-6 is required for centriole formation in embryos and integrity in embryonic stem cells.
Grzonka M, Bazzi H
eLife 2024 Feb 26;13
eLife 2024 Feb 26;13
Time-series reconstruction of the molecular architecture of human centriole assembly.
Laporte MH, Gambarotto D, Bertiaux É, Bournonville L, Louvel V, Nunes JM, Borgers S, Hamel V, Guichard P
Cell 2024 Apr 25;187(9):2158-2174.e19
Cell 2024 Apr 25;187(9):2158-2174.e19
INPP5E regulates CD3ζ enrichment at the immune synapse by phosphoinositide distribution control.
Chiu TY, Lo CH, Lin YH, Lai YD, Lin SS, Fang YT, Huang WS, Huang SY, Tsai PY, Yang FH, Chong WM, Wu YC, Tsai HC, Liu YW, Hsu CL, Liao JC, Wang WJ
Communications biology 2023 Sep 5;6(1):911
Communications biology 2023 Sep 5;6(1):911
CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis.
Wang Y, Zhang Y, Guo X, Zheng Y, Zhang X, Feng S, Wu HY
BMC biology 2023 May 24;21(1):124
BMC biology 2023 May 24;21(1):124
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
Hall EA, Kumar D, Prosser SL, Yeyati PL, Herranz-Pérez V, García-Verdugo JM, Rose L, McKie L, Dodd DO, Tennant PA, Megaw R, Murphy LC, Ferreira MF, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter JF, Mill P
eLife 2023 Feb 15;12
eLife 2023 Feb 15;12
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.
Song T, Yang Y, Zhou P, Ran J, Zhang L, Wu X, Xie W, Zhong T, Liu H, Liu M, Li D, Zhao H, Zhou J
EMBO reports 2022 May 4;23(5):e54090
EMBO reports 2022 May 4;23(5):e54090
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole.
Shen XL, Yuan JF, Qin XH, Song GP, Hu HB, Tu HQ, Song ZQ, Li PY, Xu YL, Li S, Jian XX, Li JN, He CY, Yu XP, Liang LY, Wu M, Han QY, Wang K, Li AL, Zhou T, Zhang YC, Wang N, Li HY
The Journal of cell biology 2022 Jan 3;221(1)
The Journal of cell biology 2022 Jan 3;221(1)
A ciliopathy complex builds distal appendages to initiate ciliogenesis.
Kumar D, Rains A, Herranz-Pérez V, Lu Q, Shi X, Swaney DL, Stevenson E, Krogan NJ, Huang B, Westlake C, Garcia-Verdugo JM, Yoder BK, Reiter JF
The Journal of cell biology 2021 Sep 6;220(9)
The Journal of cell biology 2021 Sep 6;220(9)
NudCL2 is an autophagy receptor that mediates selective autophagic degradation of CP110 at mother centrioles to promote ciliogenesis.
Liu M, Zhang W, Li M, Feng J, Kuang W, Chen X, Yang F, Sun Q, Xu Z, Hua J, Yang C, Liu W, Shu Q, Yang Y, Zhou T, Xie S
Cell research 2021 Nov;31(11):1199-1211
Cell research 2021 Nov;31(11):1199-1211
LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome.
Bozal-Basterra L, Gonzalez-Santamarta M, Muratore V, Bermejo-Arteagabeitia A, Da Fonseca C, Barroso-Gomila O, Azkargorta M, Iloro I, Pampliega O, Andrade R, Martín-Martín N, Branon TC, Ting AY, Rodríguez JA, Carracedo A, Elortza F, Sutherland JD, Barrio R
eLife 2020 Jun 18;9
eLife 2020 Jun 18;9
Altered gene regulation as a candidate mechanism by which ciliopathy gene SDCCAG8 contributes to schizophrenia and cognitive function.
Flynn M, Whitton L, Donohoe G, Morrison CG, Morris DW
Human molecular genetics 2020 Feb 1;29(3):407-417
Human molecular genetics 2020 Feb 1;29(3):407-417
Cep97 Is Required for Centriole Structural Integrity and Cilia Formation in Drosophila.
Dobbelaere J, Schmidt Cernohorska M, Huranova M, Slade D, Dammermann A
Current biology : CB 2020 Aug 3;30(15):3045-3056.e7
Current biology : CB 2020 Aug 3;30(15):3045-3056.e7
Neddylation inhibitor MLN4924 suppresses cilia formation by modulating AKT1.
Mao H, Tang Z, Li H, Sun B, Tan M, Fan S, Zhu Y, Sun Y
Protein & cell 2019 Oct;10(10):726-744
Protein & cell 2019 Oct;10(10):726-744
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
Lo CH, Lin IH, Yang TT, Huang YC, Tanos BE, Chou PC, Chang CW, Tsay YG, Liao JC, Wang WJ
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation.
Wang T, Zou Y, Huang N, Teng J, Chen J
Cell reports 2019 Nov 12;29(7):2078-2091.e5
Cell reports 2019 Nov 12;29(7):2078-2091.e5
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling.
Frikstad KM, Molinari E, Thoresen M, Ramsbottom SA, Hughes F, Letteboer SJF, Gilani S, Schink KO, Stokke T, Geimer S, Pedersen LB, Giles RH, Akhmanova A, Roepman R, Sayer JA, Patzke S
Cell reports 2019 Aug 13;28(7):1907-1922.e6
Cell reports 2019 Aug 13;28(7):1907-1922.e6
M-Phase Phosphoprotein 9 regulates ciliogenesis by modulating CP110-CEP97 complex localization at the mother centriole.
Huang N, Zhang D, Li F, Chai P, Wang S, Teng J, Chen J
Nature communications 2018 Oct 30;9(1):4511
Nature communications 2018 Oct 30;9(1):4511
Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome.
Bozal-Basterra L, Martín-Ruíz I, Pirone L, Liang Y, Sigurðsson JO, Gonzalez-Santamarta M, Giordano I, Gabicagogeascoa E, de Luca A, Rodríguez JA, Wilkie AOM, Kohlhase J, Eastwood D, Yale C, Olsen JV, Rauchman M, Anderson KV, Sutherland JD, Barrio R
American journal of human genetics 2018 Feb 1;102(2):249-265
American journal of human genetics 2018 Feb 1;102(2):249-265
Centrin2 regulates CP110 removal in primary cilium formation.
Prosser SL, Morrison CG
The Journal of cell biology 2015 Mar 16;208(6):693-701
The Journal of cell biology 2015 Mar 16;208(6):693-701
Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis.
Stinchcombe JC, Randzavola LO, Angus KL, Mantell JM, Verkade P, Griffiths GM
Current biology : CB 2015 Dec 21;25(24):3239-44
Current biology : CB 2015 Dec 21;25(24):3239-44
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HL-60 cells were subjected to SDS PAGE followed by western blot with 22050-1-AP(CEP97 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CEP97 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CEP97. This antibody recognizes human antigen. The CEP97 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
