DPABH-03416

antibody from Creative Diagnostics

Targeting: LDB3 CMD1C, KIAA0613, PDLIM6, ZASP

No application information provided.

Antibody Data

Product number

DPABH-03416

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-03416, RRID:AB_2520305

Product name

Rabbit Anti-Human LDB3 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified