Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8106 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- AGFG1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human AGFG1.
- Description
- HIV-1 Rev is the prototype of a class of retroviral regulatory proteins that control the sequence-specific nuclear export and translation of a class of incompletely spliced HIV-1 mRNAs that encode viral structural proteins. In the absence of Rev, these late viral RNAs remain sequestered in the nucleus until they are either spliced or degraded. The protein designated Rev interacting protein (RIP) or Rev/Rex activation domain-binding protein (Rab) contains 562 amino acids. RIP/Rab has been identified as a cellular cofactor that binds not only to the HIV-1 Rev activation domain, but also to equivalent domains of other Rev and Rex proteins. On the basis of these findings it has been speculated that RIP/Rab is required for the Rev response and thus for HIV-1 replication.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of AGFG1 polyclonal antibody