Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10507-2-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10507-2-AP, RRID:AB_2299495
- Product name
- PDZK1 antibody
- Antibody type
- Polyclonal
- Description
- PDZK1 antibody (Cat. #10507-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The mature stem of green Asparagus as a potential dietary supplement for hyperuricemia: Asparagus ameliorates hyperuricemia by regulating hepatic uric acid metabolism and renal uric acid excretion.
PDZK1 Protects Against RPE Senescence by Targeting the 14-3-3ε-mTOR Axis to Attenuate Early Diabetic Retinopathy.
PDZK1 regulated by miR-145-5p protects against endothelial cell apoptosis and diabetic retinopathy by targeting mitochondrial function.
PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma.
Lactiplantibacillus plantarum 06CC2 Enhanced the Expression of Intestinal Uric Acid Excretion Transporter in Mice.
miR-101-3p-mediated role of PDZK1 in hepatocellular carcinoma progression and the underlying PI3K/Akt signaling mechanism.
PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function.
Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.
GRP/GRPR signaling pathway aggravates hyperuricemia-induced renal inflammation and fibrosis via ABCG2-dependent mechanisms.
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
Correlation between PDZK1, Cdc37, Akt and breast cancer malignancy: the role of PDZK1 in cell growth through Akt stabilization by increasing and interacting with Cdc37.
PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.
Zhang Y, Ding Y, Wang X, Wang T, Li Z, Tan R, Li Z
Food chemistry: X 2026 Jan;33:103482
Food chemistry: X 2026 Jan;33:103482
PDZK1 Protects Against RPE Senescence by Targeting the 14-3-3ε-mTOR Axis to Attenuate Early Diabetic Retinopathy.
Zhao J, Zhang J, Liu Y, Wang L, Huang C, Chi W, An M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e11288
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e11288
PDZK1 regulated by miR-145-5p protects against endothelial cell apoptosis and diabetic retinopathy by targeting mitochondrial function.
An M, Huang J, Zhao J, Wang L, Liu Y
Experimental eye research 2025 May;254:110314
Experimental eye research 2025 May;254:110314
PDZK1 inhibits MRP2-mediated oxaliplatin chemosensitivity in hepatocellular carcinoma.
Duan Z, Li J, Ren C, Chen Y, Feng D, Ma Y, Zhao C
Scientific reports 2025 Apr 18;15(1):13438
Scientific reports 2025 Apr 18;15(1):13438
Lactiplantibacillus plantarum 06CC2 Enhanced the Expression of Intestinal Uric Acid Excretion Transporter in Mice.
Nei S, Matsusaki T, Kawakubo H, Ogawa K, Nishiyama K, Tsend-Ayush C, Nakano T, Takeshita M, Shinyama T, Yamasaki M
Nutrients 2024 Sep 9;16(17)
Nutrients 2024 Sep 9;16(17)
miR-101-3p-mediated role of PDZK1 in hepatocellular carcinoma progression and the underlying PI3K/Akt signaling mechanism.
Gao H, Gao Z, Liu X, Sun X, Hu Z, Song Z, Zhang C, Fei J, Wang X
Cell division 2024 Mar 26;19(1):9
Cell division 2024 Mar 26;19(1):9
PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function.
Shao Y, Zhang H, Guan H, Wu C, Qi W, Yang L, Yin J, Zhang H, Liu L, Lu Y, Zhao Y, Zhang S, Zeng C, Wang G, Bai X, Cai D
Bone research 2024 Jul 17;12(1):41
Bone research 2024 Jul 17;12(1):41
Promoter hypomethylated PDZK1 acts as a tumorigenic gene in glioma by interacting with AKT1.
Ren X, Deng D, Xiang S, Feng J
Aging 2024 Apr 25;16(8):7174-7187
Aging 2024 Apr 25;16(8):7174-7187
GRP/GRPR signaling pathway aggravates hyperuricemia-induced renal inflammation and fibrosis via ABCG2-dependent mechanisms.
Sun HL, Bian HG, Liu XM, Zhang H, Ying J, Yang H, Zu T, Cui GQ, Liao YF, Xu MF, Meng XM, Jin J
Biochemical pharmacology 2023 Dec;218:115901
Biochemical pharmacology 2023 Dec;218:115901
Downregulation of vimentin expression increased drug resistance in ovarian cancer cells.
Huo Y, Zheng Z, Chen Y, Wang Q, Zhang Z, Deng H
Oncotarget 2016 Jul 19;7(29):45876-45888
Oncotarget 2016 Jul 19;7(29):45876-45888
Correlation between PDZK1, Cdc37, Akt and breast cancer malignancy: the role of PDZK1 in cell growth through Akt stabilization by increasing and interacting with Cdc37.
Kim H, Abd Elmageed ZY, Davis C, El-Bahrawy AH, Naura AS, Ekaidi I, Abdel-Mageed AB, Boulares AH
Molecular medicine (Cambridge, Mass.) 2014 Jul 14;20(1):270-9
Molecular medicine (Cambridge, Mass.) 2014 Jul 14;20(1):270-9
PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.
Kim H, Abd Elmageed ZY, Ju J, Naura AS, Abdel-Mageed AB, Varughese S, Paul D, Alahari S, Catling A, Kim JG, Boulares AH
Molecular medicine (Cambridge, Mass.) 2013 Aug 28;19(1):253-62
Molecular medicine (Cambridge, Mass.) 2013 Aug 28;19(1):253-62
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PDZK1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PDZK1. This antibody recognizes human, mouse, rat antigen. The PDZK1 antibody has been validated for the following applications: ELISA, WB analysis.