BS3325

antibody from Bioworld Technology, Inc
Targeting: MRPS22 C3orf5, GIBT, GK002, MRP-S22
Provider product page for BS3325
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS3325 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS3325, RRID:AB_1914369
Product name
MRP S22 (R263) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 230-280 of Human MRP-S22.
Description
The mitoribosomes are composed of a 4:1 ratio of protein to RNA, with the proteins forming two subunits, the 28S subunit and the 39S subunit. Across species, the proteins that make up the mitoribosome subunits vary greatly in sequence, preventing easy recognition by sequence homology. MRP-S22 (mitochondrial 28S ribosomal protein S22), also known as S22mt, is a 360 amino acid mitochondrial ribosomal protein. Localized to the mitochondria, MRP-S22 is present in the 28S subunit of the mitoribosomes. Defects of MRP-S22 are the cause of combined oxidative phosphorylation deficiency type 5 (COXPD5). COXPD5 is an antenatal mitochondrial disease characterized by hypotonia, edema, cardiomyopathy and tubulopathy.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MRPS22 protein structure - BS3325 shown in red.