Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19943-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19943-1-AP, RRID:AB_10646486
- Product name
- ERBB4 antibody
- Antibody type
- Polyclonal
- Description
- ERBB4 antibody (Cat. #19943-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway.
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis.
Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes.
Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.
Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease.
EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.
Identification of targetable kinases in idiopathic pulmonary fibrosis.
DNAJC12 as a Mediator Between ESR1 and ERBB4 in Breast Carcinoma Cells.
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling.
ErbB1 and ErbB2 overexpression in patients with sinonasal inverted papilloma and inverted papilloma with squamous cell carcinoma in China.
Transactivated Epidermal Growth Factor Receptor Recruitment of α-actinin-4 From F-actin Contributes to Invasion of Brain Microvascular Endothelial Cells by Meningitic Escherichia coli.
EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis.
Wang X, Wu H, Tang L, Fu W, He Y, Zeng C, Wang WE
Journal of molecular and cellular cardiology 2024 Feb;187:26-37
Journal of molecular and cellular cardiology 2024 Feb;187:26-37
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
Gao YZ, Wu XM, Zhou ZQ, Liu PM, Yang JJ, Ji MH
Molecular neurobiology 2023 Jun;60(6):3210-3226
Molecular neurobiology 2023 Jun;60(6):3210-3226
Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis.
Zhang Y, Zhu Y, Wang J, Jin L, Guo M, Chen L, Zhang L, Li Y, Wan B, Zhang R, Jia W, Hu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2204824
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2204824
Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes.
Ye D, Wang Q, Yang Y, Chen B, Zhang F, Wang Z, Luan Z
Cellular and molecular neurobiology 2023 Jul;43(5):2337-2358
Cellular and molecular neurobiology 2023 Jul;43(5):2337-2358
Hepatitis B virus X protein increases LASP1 SUMOylation to stabilize HER2 and facilitate hepatocarcinogenesis.
You H, Yuan D, Li Q, Zhang N, Kong D, Yu T, Liu X, Liu X, Zhou R, Kong F, Zheng K, Tang R
International journal of biological macromolecules 2023 Jan 31;226:996-1009
International journal of biological macromolecules 2023 Jan 31;226:996-1009
Neuregulin-1 attenuates hemolysis- and ischemia induced-cerebrovascular inflammation associated with sickle cell disease.
Chambliss C, Stiles JK, Gee BE
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Feb;32(2):106912
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2023 Feb;32(2):106912
EGFR promotes ALKBH5 nuclear retention to attenuate N6-methyladenosine and protect against ferroptosis in glioblastoma.
Lv D, Zhong C, Dixit D, Yang K, Wu Q, Godugu B, Prager BC, Zhao G, Wang X, Xie Q, Bao S, He C, Heiland DH, Rosenfeld MG, Rich JN
Molecular cell 2023 Dec 7;83(23):4334-4351.e7
Molecular cell 2023 Dec 7;83(23):4334-4351.e7
Identification of targetable kinases in idiopathic pulmonary fibrosis.
Higo H, Ohashi K, Tomida S, Okawa S, Yamamoto H, Sugimoto S, Senoo S, Makimoto G, Ninomiya K, Nakasuka T, Nishii K, Taniguchi A, Kubo T, Ichihara E, Hotta K, Miyahara N, Maeda Y, Toyooka S, Kiura K
Respiratory research 2022 Feb 7;23(1):20
Respiratory research 2022 Feb 7;23(1):20
DNAJC12 as a Mediator Between ESR1 and ERBB4 in Breast Carcinoma Cells.
Lin M, Wang YN, Ye Y, Xiong Z, Guo F, Chen H
Frontiers in oncology 2021;11:582277
Frontiers in oncology 2021;11:582277
MicroRNA-936/ERBB4/Akt axis exhibits anticancer properties of gastric cancer through inhibition of cell proliferation, migration, and invasion.
Liu S, Gong Y, Xu XD, Shen H, Gao S, Bao HD, Guo SB, Yu XF, Gong J
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
The Kaohsiung journal of medical sciences 2021 Feb;37(2):111-120
AK003290 Protects Myocardial Cells Against Apoptosis and Promotes Cardiac Function Recovery Via miR-539-3p/ErbB4 Axis in Ischemic-Reperfusion Injury.
Tang Y, Tang Y, Xiang Y, Yan J, Guo K
DNA and cell biology 2021 Dec;40(12):1528-1538
DNA and cell biology 2021 Dec;40(12):1528-1538
JAC1 suppresses proliferation of breast cancer through the JWA/p38/SMURF1/HER2 signaling.
Ren Y, Chen D, Zhai Z, Chen J, Li A, Liang Y, Zhou J
Cell death discovery 2021 Apr 19;7(1):85
Cell death discovery 2021 Apr 19;7(1):85
ErbB1 and ErbB2 overexpression in patients with sinonasal inverted papilloma and inverted papilloma with squamous cell carcinoma in China.
Li H, Hu L, Zhang H, Wang D
Acta oto-laryngologica 2019 Dec;139(12):1104-1111
Acta oto-laryngologica 2019 Dec;139(12):1104-1111
Transactivated Epidermal Growth Factor Receptor Recruitment of α-actinin-4 From F-actin Contributes to Invasion of Brain Microvascular Endothelial Cells by Meningitic Escherichia coli.
Fu J, Li L, Yang X, Yang R, Amjad N, Liu L, Tan C, Chen H, Wang X
Frontiers in cellular and infection microbiology 2018;8:448
Frontiers in cellular and infection microbiology 2018;8:448
EGFR transactivation contributes to neuroinflammation in Streptococcus suis meningitis.
Yang XP, Fu JY, Yang RC, Liu WT, Zhang T, Yang B, Miao L, Dou BB, Tan C, Chen HC, Wang XR
Journal of neuroinflammation 2016 Oct 19;13(1):274
Journal of neuroinflammation 2016 Oct 19;13(1):274
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 19943-1-AP(ERBB4 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 19943-1-AP(ERBB4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ERBB4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ERBB4. This antibody recognizes human,mouse,rat antigen. The ERBB4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.