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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Product number
- ABIN108570 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-MUS81 Endonuclease Homolog (S. Cerevisiae) (MUS81) antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- MTA30 2G10-3
- Vial size
- 50 μL
- Storage
- 4°C
Submitted references CtIP is required to initiate replication-dependent interstrand crosslink repair.
Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN.
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype.
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease.
Mechanism of Holliday junction resolution by the human GEN1 protein.
Telomere recombination requires the MUS81 endonuclease.
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.
Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures.
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
Duquette ML, Zhu Q, Taylor ER, Tsay AJ, Shi LZ, Berns MW, McGowan CH
PLoS genetics 2012;8(11):e1003050
PLoS genetics 2012;8(11):e1003050
Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN.
Murfuni I, De Santis A, Federico M, Bignami M, Pichierri P, Franchitto A
Carcinogenesis 2012 Sep;33(9):1655-63
Carcinogenesis 2012 Sep;33(9):1655-63
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.
Regairaz M, Zhang YW, Fu H, Agama KK, Tata N, Agrawal S, Aladjem MI, Pommier Y
The Journal of cell biology 2011 Nov 28;195(5):739-49
The Journal of cell biology 2011 Nov 28;195(5):739-49
SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype.
Stoepker C, Hain K, Schuster B, Hilhorst-Hofstee Y, Rooimans MA, Steltenpool J, Oostra AB, Eirich K, Korthof ET, Nieuwint AW, Jaspers NG, Bettecken T, Joenje H, Schindler D, Rouse J, de Winter JP
Nature genetics 2011 Feb;43(2):138-41
Nature genetics 2011 Feb;43(2):138-41
Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease.
Domínguez-Kelly R, Martín Y, Koundrioukoff S, Tanenbaum ME, Smits VA, Medema RH, Debatisse M, Freire R
The Journal of cell biology 2011 Aug 22;194(4):567-79
The Journal of cell biology 2011 Aug 22;194(4):567-79
Mechanism of Holliday junction resolution by the human GEN1 protein.
Rass U, Compton SA, Matos J, Singleton MR, Ip SC, Blanco MG, Griffith JD, West SC
Genes & development 2010 Jul 15;24(14):1559-69
Genes & development 2010 Jul 15;24(14):1559-69
Telomere recombination requires the MUS81 endonuclease.
Zeng S, Xiang T, Pandita TK, Gonzalez-Suarez I, Gonzalo S, Harris CC, Yang Q
Nature cell biology 2009 May;11(5):616-23
Nature cell biology 2009 May;11(5):616-23
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
Svendsen JM, Smogorzewska A, Sowa ME, O'Connell BC, Gygi SP, Elledge SJ, Harper JW
Cell 2009 Jul 10;138(1):63-77
Cell 2009 Jul 10;138(1):63-77
Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.
Franchitto A, Pirzio LM, Prosperi E, Sapora O, Bignami M, Pichierri P
The Journal of cell biology 2008 Oct 20;183(2):241-52
The Journal of cell biology 2008 Oct 20;183(2):241-52
Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures.
Taylor ER, McGowan CH
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 11;105(10):3757-62
Proceedings of the National Academy of Sciences of the United States of America 2008 Mar 11;105(10):3757-62
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
Nomura Y, Adachi N, Koyama H
Genes to cells : devoted to molecular & cellular mechanisms 2007 Oct;12(10):1111-22
Genes to cells : devoted to molecular & cellular mechanisms 2007 Oct;12(10):1111-22
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