Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12053-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12053-1-AP, RRID:AB_2161180
- Product name
- PELI1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PELI1 antibody (Cat. #12053-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references miR-369-3p Regulates Microglia Polarization and Neuroinflammation in Traumatic Spinal Cord Injury by Targeting PELI1.
Pellino1 Exacerbates Diabetic Kidney Disease Through NLRP3 Inflammasome Driven Pyroptosis in Renal Tubular Epithelial Cells.
PRMT1/PRMT5-Mediated Differential Arginine Methylation of CRIP1 Promotes the Recurrence of Small Cell Lung Cancer after Chemotherapy.
Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins.
PELI1 overexpression contributes to pancreatic cancer progression through upregulating ubiquitination-mediated INPP5J degradation.
Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency.
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Li Y, Sun G, Lin R, Huang Y
Global spine journal 2026 Jan 2;:21925682251406197
Global spine journal 2026 Jan 2;:21925682251406197
Pellino1 Exacerbates Diabetic Kidney Disease Through NLRP3 Inflammasome Driven Pyroptosis in Renal Tubular Epithelial Cells.
Zhou X, Zhang R, Guo Z, Yang Y, Yan R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71721
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 15;40(7):e71721
PRMT1/PRMT5-Mediated Differential Arginine Methylation of CRIP1 Promotes the Recurrence of Small Cell Lung Cancer after Chemotherapy.
Han Y, Ma L, Zhang X, Ren Q, Yuan Q, Zhou J, Ren Y, Wan N, Jin X, Hou J, Wang Y, Huang B, Zhang Y, Lu J
International journal of biological sciences 2025;21(13):5956-5974
International journal of biological sciences 2025;21(13):5956-5974
Cathepsin D promotes acute myeloid leukemia progression through stabilization of the anti-apoptotic proteins.
Jiang H, Wang Y, Wang C, Yang L, Wang S, Wang F, Xue S, Zhang Z, Fu H, Dong T, Yuan J, Li Z, Li K
Cell death & disease 2025 Aug 12;16(1):611
Cell death & disease 2025 Aug 12;16(1):611
PELI1 overexpression contributes to pancreatic cancer progression through upregulating ubiquitination-mediated INPP5J degradation.
Zhou W, Deng X, Liu L, Yuan Y, Meng X, Ma J
Cellular signalling 2024 Aug;120:111194
Cellular signalling 2024 Aug;120:111194
Regulatory T Cells Overexpressing Peli1 Show Better Efficacy in Repairing Ovarian Endocrine Function in Autoimmune Premature Ovarian Insufficiency.
Wang Y, Zhuo A, Yang Y, Wang Q, Xie J, Ma W, Chen Y, Gao M, Tang L, Fu X
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100005
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100005
MiR-30c-5p loss-induced PELI1 accumulation regulates cell proliferation and migration via activating PI3K/AKT pathway in papillary thyroid carcinoma.
Zheng T, Zhou Y, Xu X, Qi X, Liu J, Pu Y, Zhang S, Gao X, Luo X, Li M, Wang X, Dong L, Wang Y, Mao C
Journal of translational medicine 2022 Jan 6;20(1):20
Journal of translational medicine 2022 Jan 6;20(1):20
Peli1 impairs microglial Aβ phagocytosis through promoting C/EBPβ degradation.
Xu J, Yu T, Pietronigro EC, Yuan J, Arioli J, Pei Y, Luo X, Ye J, Constantin G, Mao C, Xiao Y
PLoS biology 2020 Oct;18(10):e3000837
PLoS biology 2020 Oct;18(10):e3000837
MiR-153-3p induces immune dysregulation by inhibiting PELI1 expression in umbilical cord-derived mesenchymal stem cells in patients with systemic lupus erythematosus.
Li D, Li X, Duan M, Dou Y, Feng Y, Nan N, Zhang W
Autoimmunity 2020 Jun;53(4):201-209
Autoimmunity 2020 Jun;53(4):201-209
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The PELI1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PELI1. This antibody recognizes human, mouse, rat antigen. The PELI1 antibody has been validated for the following applications: ELISA, WB analysis.