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- References [10]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17628-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17628-1-AP, RRID:AB_2171654
- Product name
- PRMT3 antibody
- Antibody type
- Polyclonal
- Description
- PRMT3 antibody (Cat. #17628-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Discovery of the First-in-Class Protein Arginine Methyltransferase 1 PROTAC Degrader.
PRMT3-mediated post-translational adaptation to fasting regulates metabolic flexibility.
A novel 3-alkenylindol-2-one derivative selectively inhibits the growth of acute myeloid leukemia via modulation of the MYC-PRMT pathway.
Dynamic Arginine Methylation of YBX1 Relay Controls Its Phase Separation and Chemoradiotherapy Resistance in Rectal Cancer.
Chicken PRMT3 facilitates IBDV replication.
Targeting PRMT3 impairs methylation and oligomerization of HSP60 to boost anti-tumor immunity by activating cGAS/STING signaling.
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Shotgun proteomic investigation of methyltransferase and methylation profiles in lipopolysaccharide stimulated RAW264.7 murine macrophages.
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5.
Ribavirin inhibits the growth and ascites formation of hepatocellular carcinoma through downregulation of type I CARM1 and type II PRMT5.
Guo S, Li J, Lin J, Chen Y, Liu C, Liu H, He Z, Zhu Y, Wang L, Yang F, Luo C, Li Z, Jin J, Ye F
Journal of medicinal chemistry 2026 Mar 26;69(6):6775-6789
Journal of medicinal chemistry 2026 Mar 26;69(6):6775-6789
PRMT3-mediated post-translational adaptation to fasting regulates metabolic flexibility.
Huang Z, Liu X, Chen X, Zhou Y, Chen Q, Liu Y, Zhu H, Cheng K, Feng Y, Dong M, Song L, Wang L, Liu S, Shan T, Kuang S, Dong Y, Vidal-Puig A, Zhang Y, Jia Z
Nature communications 2026 Feb 2;17(1)
Nature communications 2026 Feb 2;17(1)
A novel 3-alkenylindol-2-one derivative selectively inhibits the growth of acute myeloid leukemia via modulation of the MYC-PRMT pathway.
Dong S, Yang R, Wang Y, Fang X, Han X, Gu M, Chen S, Zhang B
Biochemical pharmacology 2025 Oct;240:117111
Biochemical pharmacology 2025 Oct;240:117111
Dynamic Arginine Methylation of YBX1 Relay Controls Its Phase Separation and Chemoradiotherapy Resistance in Rectal Cancer.
Shi Y, Wan T, Liu S, Liu H, Zeng Z, Li W, Liang Z, Xiong L, Luo S, Yuan Y, Huang L, Kang L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e02786
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e02786
Chicken PRMT3 facilitates IBDV replication.
Xiong Z, Cao J, Xiu M, Li A, Li X, Zhang Y, Zeng Q, Hu Y, Yang Y, Wu H
Poultry science 2024 Sep;103(9):103989
Poultry science 2024 Sep;103(9):103989
Targeting PRMT3 impairs methylation and oligomerization of HSP60 to boost anti-tumor immunity by activating cGAS/STING signaling.
Shi Y, Wu Z, Liu S, Zuo D, Niu Y, Qiu Y, Qiao L, He W, Qiu J, Yuan Y, Wang G, Li B
Nature communications 2024 Sep 10;15(1):7930
Nature communications 2024 Sep 10;15(1):7930
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Zhou G, Zhang C, Peng H, Su X, Huang Q, Zhao Z, Zhao G
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Shotgun proteomic investigation of methyltransferase and methylation profiles in lipopolysaccharide stimulated RAW264.7 murine macrophages.
Aizawa Y, Mori M, Suzuki T, Saito A, Inoue H
Biomedical research (Tokyo, Japan) 2022;43(3):73-80
Biomedical research (Tokyo, Japan) 2022;43(3):73-80
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5.
Zhang Q, Yang R, Tian Y, Ge S, Nan X, Zhu S, Dong S, Zhang B
Basic & clinical pharmacology & toxicology 2022 Jul;131(1):18-33
Basic & clinical pharmacology & toxicology 2022 Jul;131(1):18-33
Ribavirin inhibits the growth and ascites formation of hepatocellular carcinoma through downregulation of type I CARM1 and type II PRMT5.
Tian Y, Yang W, Yang R, Zhang Q, Hao L, Bian E, Yang Y, Huang X, Wu Y, Zhang B
Toxicology and applied pharmacology 2022 Jan 15;435:115829
Toxicology and applied pharmacology 2022 Jan 15;435:115829
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 17628-1-AP(PRMT3 antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 17628-1-AP(PRMT3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRMT3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PRMT3. This antibody recognizes human,mouse,rat antigen. The PRMT3 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
