NBP2-54402JF646

antibody from Novus Biologicals

Targeting: KRT10 CK10, K10, KPP

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

NBP2-54402JF646

Provider

Novus Biologicals

Product name

Mouse Monoclonal Cytokeratin 10 Antibody

Antibody type

Monoclonal

Description

Protein A or G purified. This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

Reactivity

Human, Canine, Feline

Host

Mouse

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C in the dark.