CABT-B039

antibody from Creative Diagnostics
Targeting: CD52 CDW52, EDDM5, HE5
Provider product page for CABT-B039
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
CABT-B039 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-CD52 monoclonal antibody, clone NIT9-B6-B2-E8
Antibody type
Monoclonal
Description
Human CD52 is a glycosylphosphatidylinositol (GPI)-anchored antigen expressed on the all lymphocytes as well as within the male genital tract, where it can be produced by epithelial cells of the distal epididymis and duct deferens. CD52 can be shed into seminal plasma and then acquired by sperm cells during their passage through the genital tract, thus it is detectable on the surface of epididymal sperm and in the ejaculate but not on either spermatogenetic cells or testicular spermatozoa. Protein core of the sperm and lymphocyte CD52 is identical and it is a product of a single copy gene located on chromosome 1. However, N-linked carbohydrate side chains (attached to Asn-3) and GPI-anchor structure are different. Monoclonal antibodies directed against sperm CD52 may cause sperm immobilisation and agglutination and affect hamster oocyte penetration suggesting an association of this molecule with fertilisation.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Antibody clone number
NIT9-B6-B2-E8
Vial size
100_g
Concentration
1mg/mL
Storage
Store at -20°C
CD52 protein structure - CABT-B039 shown in red.