FNab08425

antibody from FineTest Biotech

Targeting: SYT1 P65, SVP65, SYT

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ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: FNab08425 - Provider product page
Provider: FineTest Biotech
Product name: Synaptotagmin-1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis(PMID: 8058779). SYT1(synaptotagmin I) was firstly identified as a 65-kDa protein with a wide distribution in neuronal and neurosecretory tissue(PMID: 7298720). Calcium binding to SYT1 participates in triggering neurotransmitter release at the synapse(PMID: 11242035). In addition to regulating exocytosis, SYT1 has also been implicated in endocytosis and neurite outgrowth(PMID: 15492212; 11078930; 10336114). This antibody recognizes endogenous SYT1, which has an experimentally determined molecular mass of 65-68 kDa. An additional band of 47 kDa could also be detected, which is corresponding to the calculated molecular weight of SYT1.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: synaptotagmin I
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

SYT1 protein structure - FNab08425 shown in red.