Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 18790-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18790-1-AP, RRID:AB_10597093
- Product name
- GNMT antibody
- Antibody type
- Polyclonal
- Description
- GNMT antibody (Cat. #18790-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Brucine Suppresses Malignant Progression of Prostate Cancer by Decreasing Sarcosine Accumulation via Downregulation of GNMT in the Glycine/sarcosine Metabolic Pathway.
Parental betaine supplementation promotes gosling growth with epigenetic modulation of IGF gene family in the liver.
The Immunohistochemical Profile of Mammary Tissue in Women With Macromastia and Its Potential Clinical Implications.
Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers.
In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses.
Nuclear localization dictates hepatocarcinogenesis suppression by glycine N-methyltransferase.
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients.
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes.
Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
Transgenerational Inheritance of Betaine-Induced Epigenetic Alterations in Estrogen-Responsive IGF-2/IGFBP2 Genes in Rat Hippocampus.
Elevated N-methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform.
DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.
Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†.
Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression.
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation.
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Miao L, Liu Y, Chen W, Gao C, Zhang Y, Wei J, Cao X
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
Cell biochemistry and biophysics 2024 Sep;82(3):2373-2385
Parental betaine supplementation promotes gosling growth with epigenetic modulation of IGF gene family in the liver.
Ma S, Wang Y, Chen L, Wang W, Zhuang X, Liu Y, Zhao R
Journal of animal science 2024 Jan 3;102
Journal of animal science 2024 Jan 3;102
The Immunohistochemical Profile of Mammary Tissue in Women With Macromastia and Its Potential Clinical Implications.
Antoszewski B, Kasielska-Trojan A, Jones TE, Danilewicz M, Jones MW
Endocrinology 2024 Feb 20;165(4)
Endocrinology 2024 Feb 20;165(4)
Glycogen Storage Disease Phenotypes Accompanying the Perturbation of the Methionine Cycle in NDRG3-Deficient Mouse Livers.
Sohn HA, Lee DC, Park A, Kang M, Yoon BH, Lee CH, Kim YH, Oh KJ, Kim CY, Park SH, Koo H, Kim HC, Yoon WK, Lim DS, Kim D, Park KC, Yeom YI
Cells 2022 May 4;11(9)
Cells 2022 May 4;11(9)
In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses.
Abobaker H, Omer NA, Hu Y, Idriss AA, Zhao R
Poultry science 2022 Jun;101(6):101871
Poultry science 2022 Jun;101(6):101871
Nuclear localization dictates hepatocarcinogenesis suppression by glycine N-methyltransferase.
Simile MM, Cigliano A, Paliogiannis P, Daino L, Manetti R, Feo CF, Calvisi DF, Feo F, Pascale RM
Translational oncology 2022 Jan;15(1):101239
Translational oncology 2022 Jan;15(1):101239
Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction.
Rome FI, Hughey CC
Molecular metabolism 2022 Apr;58:101452
Molecular metabolism 2022 Apr;58:101452
MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients.
Chu PY, Wu HJ, Wang SM, Chen PM, Tang FY, Chiang EI
International journal of molecular sciences 2021 May 20;22(10)
International journal of molecular sciences 2021 May 20;22(10)
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes.
Omer NA, Hu Y, Idriss AA, Abobaker H, Hou Z, Yang S, Ma W, Zhao R
Poultry science 2020 Jun;99(6):3121-3132
Poultry science 2020 Jun;99(6):3121-3132
Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
Hu Y, Feng Y, Ding Z, Lv L, Sui Y, Sun Q, Abobaker H, Cai D, Zhao R
Poultry science 2020 Jun;99(6):3111-3120
Poultry science 2020 Jun;99(6):3111-3120
Transgenerational Inheritance of Betaine-Induced Epigenetic Alterations in Estrogen-Responsive IGF-2/IGFBP2 Genes in Rat Hippocampus.
Yang Y, Jiang W, Yang S, Qi F, Zhao R
Molecular nutrition & food research 2020 Apr;64(8):e1900823
Molecular nutrition & food research 2020 Apr;64(8):e1900823
Elevated N-methyltransferase expression induced by hepatic stellate cells contributes to the metastasis of hepatocellular carcinoma via regulation of the CD44v3 isoform.
Li J, You S, Zhang S, Hu Q, Wang F, Chi X, Zhao W, Xie C, Zhang C, Yu Y, Liu J, Zhao Y, Liu P, Zhang Y, Wei X, Li Q, Wang X, Yin Z
Molecular oncology 2019 Sep;13(9):1993-2009
Molecular oncology 2019 Sep;13(9):1993-2009
DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.
Yang Y, Yang S, Liu J, Feng Y, Qi F, Zhao R
Molecular nutrition & food research 2019 Jun;63(12):e1801334
Molecular nutrition & food research 2019 Jun;63(12):e1801334
Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†.
Jia L, Zeng Y, Hu Y, Liu J, Yin C, Niu Y, Wang C, Li J, Jia Y, Hong J, Zhao R
Biology of reproduction 2019 Apr 1;100(4):907-916
Biology of reproduction 2019 Apr 1;100(4):907-916
Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression.
Omer NA, Hu Y, Hu Y, Idriss AA, Abobaker H, Hou Z, Dong H, Zhao R
Journal of animal science and biotechnology 2018;9:2
Journal of animal science and biotechnology 2018;9:2
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
Hu Y, Sun Q, Hu Y, Hou Z, Zong Y, Omer NA, Abobaker H, Zhao R
The Journal of nutrition 2018 Mar 1;148(3):316-325
The Journal of nutrition 2018 Mar 1;148(3):316-325
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
Zhao N, Yang S, Jia Y, Sun B, He B, Zhao R
The Journal of nutritional biochemistry 2018 Apr;54:105-112
The Journal of nutritional biochemistry 2018 Apr;54:105-112
Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation.
Zhao N, Yang S, Hu Y, Dong H, Zhao R
Molecular nutrition & food research 2017 Aug;61(8)
Molecular nutrition & food research 2017 Aug;61(8)
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, Zhao R
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, Zhao R
Nutrients 2016 Oct 18;8(10)
Nutrients 2016 Oct 18;8(10)
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R
Journal of agricultural and food chemistry 2016 Oct 12;64(40):7530-7539
Journal of agricultural and food chemistry 2016 Oct 12;64(40):7530-7539
Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.
Jia L, Li J, He B, Jia Y, Niu Y, Wang C, Zhao R
Scientific reports 2016 Jan 13;6:19436
Scientific reports 2016 Jan 13;6:19436
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
Li X, Sun Q, Li X, Cai D, Sui S, Jia Y, Song H, Zhao R
European journal of nutrition 2015 Oct;54(7):1201-10
European journal of nutrition 2015 Oct;54(7):1201-10
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Jia Y, Song H, Gao G, Cai D, Yang X, Zhao R
Journal of agricultural and food chemistry 2015 Nov 25;63(46):10152-60
Journal of agricultural and food chemistry 2015 Nov 25;63(46):10152-60
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GNMT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GNMT. This antibody recognizes human, mouse, rat antigen. The GNMT antibody has been validated for the following applications: ELISA, WB analysis.
