26864-1-AP

antibody from Proteintech Group

Targeting: SLC7A11 xCT

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26864-1-AP

Provider

Proteintech Group

Product name

SLC7A11/xCT antibody

Antibody type

Polyclonal

Description

KD/KO validated SLC7A11/xCT antibody (Cat. #26864-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.

Ni H, Ruan G, Sun C, Yang X, Miao Z, Li J, Chen Y, Qin H, Liu Y, Zheng L, Xing Y, Xi T, Li X
Environmental toxicology 2022 Feb;37(2):192-200

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Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.

Song Q, Liao W, Chen X, He Z, Li, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343

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Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.

Li L, Li H, Li Y, Feng J, Guan D, Zhang Y, Fu Y, Li S, Li C
Oxidative medicine and cellular longevity 2021;2021:5594059

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Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.

Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400

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Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT.

Zheng YW, Miao XY, Xiong L, Chen B, Kong FH, Zhou JJ, Liu ZT, Wen Y, Zhang ZJ, Zou H
Frontiers in pharmacology 2021;12:723488

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Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.

Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223

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Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.

Li P, Jiang M, Li K, Li H, Zhou Y, Xiao X, Xu Y, Krishfield S, Lipsky PE, Tsokos GC, Zhang X
Nature immunology 2021 Sep;22(9):1107-1117

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Anti-PD-L1 DNAzyme Loaded Photothermal Mn²⁺ /Fe³⁺ Hybrid Metal-Phenolic Networks for Cyclically Amplified Tumor Ferroptosis-Immunotherapy.

Liu P, Shi X, Peng Y, Hu J, Ding J, Zhou W
Advanced healthcare materials 2021 Nov 29;:e2102315

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Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.

Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188

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MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis.

Ni H, Qin H, Sun C, Liu Y, Ruan G, Guo Q, Xi T, Xing Y, Zheng L
Stem cell research & therapy 2021 Jun 5;12(1):325

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Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.

Guo L, Zhang T, Wang F, Chen X, Xu H, Zhou C, Chen M, Yu F, Wang S, Yang D, Wu B
British journal of pharmacology 2021 Jan;178(2):328-345

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A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis.

Wang Z, Chen X, Liu N, Shi Y, Liu Y, Ouyang L, Tam S, Xiao D, Liu S, Wen F, Tao Y
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):263-274

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Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms.

Sun L, Dong H, Zhang W, Wang N, Ni N, Bai X, Liu N
DNA and cell biology 2021 Feb;40(2):172-183

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CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.

Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142

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IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.

Zhang L, Liu W, Liu F, Wang Q, Song M, Yu Q, Tang K, Teng T, Wu D, Wang X, Han W, Li Y
Oxidative medicine and cellular longevity 2020;2020:1675613

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Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.

Hoshino T, Yamakado H, Takahashi R, Matsuzawa SI
FEBS open bio 2020 Sep;10(9):1758-1764

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Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.

Xu X, Zhang X, Wei C, Zheng D, Lu X, Yang Y, Luo A, Zhang K, Duan X, Wang Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450

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The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma.

Tang B, Zhu J, Li J, Fan K, Gao Y, Cheng S, Kong C, Zheng L, Wu F, Weng Q, Lu C, Ji J
Cell communication and signaling : CCS 2020 Oct 28;18(1):174

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Discovery of a novel ferroptosis inducer-talaroconvolutin A-killing colorectal cancer cells in vitro and in vivo.

Xia Y, Liu S, Li C, Ai Z, Shen W, Ren W, Yang X
Cell death & disease 2020 Nov 17;11(11):988

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Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.

Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574

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Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.

Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, Sampilvanjil A, Ito J, Nakagawa K, Kuwata H, Hara S, Mizuta K, Sakuma Y, Sata N, Takahashi M
Cell death & disease 2020 Feb 24;11(2):144