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- Antigen structure
- References [865]
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- Product number
- 26864-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SLC7A11/xCT antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SLC7A11/xCT antibody (Cat. #26864-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis.
Aloperine Induces Ferroptosis of Colorectal Cancer Cells via the Nrf2 Pathway.
Actinidia chinensis Planch Root extracts trigger ferroptosis in colorectal cancer via the p53/SLC7A11/GPX4 axis.
Epigenetic activation of SLC7A11 defines a ferroptosis-immune axis and enables robust DNA methylation-based diagnosis of lung squamous cell carcinoma.
The contribution of ferroptosis to the epithelial-mesenchymal transition phenotype in models of age-related macular degeneration.
Monitoring early micro-oxidation under refrigeration: iron and oxidative markers predict quality loss in grass carp.
ETV4 transcriptionally activates STAT6 to inhibit ferroptosis and promote immune escape in thyroid cancer.
Ginsenoside Rb2 Attenuates Microvascular Endothelial Stress Injury by Mediating Mitochondrial Pathway Pyroptosis via the DNA-PKcs-SIRT5 Axis.
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Multi-omics reveals that 4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota.
Yitangkang decoction in the treatment of glomerular filtration barrier damage through AMPKα1/ZDHHC8/SLC7A11/GPX4 and TGF-β/Smad signaling pathways: A multi-omics analysis.
NUP62 promotes breast cancer progression and inhibits ferroptosis by stabilizing NRF2 in a KEAP1-dependent way.
Multifunctionally Modified Low Molecular Weight PEI for Efficient Gene Delivery and Ferroptosis-Induced Antitumor Activity.
Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis.
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Concurrent Ferroptosis and Apoptosis in Resveratrol-Treated Glioblastoma Cells: Relevance With NRF2 Downregulation and Oxidative Stress.
PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury.
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
Apatinib and silver nanoparticles synergize against gastric cancer through the PI3K/Akt signaling pathway-mediated ferroptosis.
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis.
USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer.
Trolline attenuates diabetic vascular injury by regulating SLC7A11-mediated ferroptosis and mitochondrial dysfunction.
Curcumin protects against difenoconazole-induced kidney injury in carp by inhibiting ferroptosis through the Nrf2/GPX4 axis.
NOX1/4 drives hepatic iron and lipid dysregulation, redox imbalance, and inflammation in ethanol-fed mice.
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
The effect and mechanism of albiflorin in alleviating hepatic fibrosis by mediating hepatocyte ferroptosis via the SLC7A11/GPX4 signaling pathway.
Disulfidptosis induced by intermittent fasting and metformin enhances the efficacy of anti-PD-1 therapy in renal cancer.
FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.
Study on the effects and mechanisms of M2 macrophages on PYCR1-promoted biological behavior of hepatocellular carcinoma cells.
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
AMBRA1 activation alleviates zearalenone-induced swine testicular cell ferroptosis by facilitating mitophagy.
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Protean bio-heterojunction nanoparticle coating for dynamically modulating diabetic microenvironment.
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Role of PTP1B in coordinating synaptic plasticity and ferroptosis: A mechanism underlying the antidepressant effect of spinosin from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou.
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
CDDO-Me alleviates doxorubicin/lapatinib-induced cardiotoxicity by activating the NRF2/GPX4 axis to inhibit oxidative stress and ferroptosis.
Pyrvinium pamoate inhibits the survival of intracellular Mycobacterium tuberculosis through suppression of macrophage ferroptosis.
Design and synthesis of dual mitochondria-targeted biguanide derivatives as potential anticancer agents.
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Identifying cathepsin B as a key regulator of programmed cell death in acute pancreatitis.
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Muskardia inhibits proliferation and migration of human coronary artery smooth muscle cells by regulating SLC7A11 mRNA stability via the hsa_circTEX10-PCBP2 Axis.
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells.
Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation.
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Dictamnine inhibited keratinocyte hyperproliferation and alleviated psoriasis-like dermatitis via blocking HIF1A-mediated ferroptotic pathway.
Rottlerin triggers dual degradation of SLC7A11 and GPX4 to drive ferroptosis and chemosensitization in hepatocellular carcinoma.
Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway.
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Ferroptosis-related gene signature predicts prognosis and immunotherapy response in hepatocellular carcinoma: A multi-cohort retrospective study.
Integrating bioinformatic analyses and experimental validation of disulfidptosis-related genes and TMX4 in melanoma progression.
Moscatilin alleviates severe acute pancreatitis by activating the NRF2/HO-1 pathway to inhibit ferroptosis.
SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer.
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries.
NSUN2 Knockdown Promotes the Ferroptosis of Colorectal Cancer Cells Via m5C Modification of SLC7A11 mRNA.
Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway.
Integrating TWAS, chemical-genomic networks, and experimental models: melatonin as a ferroptosis inhibitor in osteoarthritis therapy.
Protective Effects of Liriodendrin Against Oxidative Stress and Ferroptosis in a Mouse Model of Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Smart responsive injectable hydrogel loaded with icariin inhibits ferroptosis and promotes nucleus pulposus repair in intervertebral disc degeneration.
A Functional Nanocomposite Tri-Activates Cuproptosis, Ferroptosis, and Mitophagy Death Pathway to Oppose Malignancies.
Melatonin counteracts Iodoacetic acid induced ferroptosis by regulating Nrf2 in porcine oocytes.
Curcumin pretreatment enhances the capacity of BMSC exosomes to attenuate renal ischemia-reperfusion injury by ferroptosis suppression via miR-16-5p/Smad3/Mb axis.
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
A novel mechanism of chlorogenic acid against type 2 diabetes-induced diabetic retinopathy: suppressing ferroptosis via NRF2/xCT/GPX4 and STAT3 signaling.
Targeting mitochondrial phosphatase PGAM5 alleviates ferroptosis and acute pancreatitis by upregulating NRF2-mediated FSP1 expression.
Saposhnikovia divaricata Inhibits Inflammation, Oxidative Stress, and Ferroptosis to Alleviate DSS-Induced Ulcerative Colitis.
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
Integrated multi-omics analysis reveals GPD1L-mediated dysregulation of glycerophospholipid metabolism facilitates the progression of lung adenocarcinoma.
Supplemental exposure to polystyrene nanoplastics synergistically amplifies calcium oxalate crystal-induced injury to renal tubular epithelium, accelerating the formation of calcium oxalate kidney stones.
TFEB-nuclear translocation promotes BNIP3-mediated mitophagy and alleviates oxidative stress and ferroptosis in acute pancreatitis.
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Nrf2 de-SUMOylation alleviates myocardial ischemia-reperfusion injury (MIRI) by attenuating myocardial ferroptosis in mice.
Xin Jia congrong tusizi decoction reverses ferroptosis in granulosa cells to rescue ovarian function decline via p53/Nrf2/SLC7A11/GPX4 signaling pathway.
Ageing promotes metastasis via activation of the integrated stress response.
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
Puerarin promotes nerve regeneration and functional recovery after peripheral nerve injury by inhibiting ACSL4-dependent ferroptosis.
Di-(2-Ethylhexyl) phthalate causes testicular ferroptosis though deficiency of androgen receptor and disruption of mitochondrial quality control.
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
Apigenin-5-O-glucoside alleviates hepatic fibrosis through NOX4-mediated ferroptosis in zebrafish.
Remimazolam Ameliorates Autistic-Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD.
Inhibition of Calcium-Dependent Lipid Droplets Relocation of ACSL4-PKCβ-ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis.
Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease.
Stabilizing MARCH7 as a ferro-guardian against ferroptosis.
Downregulation of SELENOS Suppresses the Progression of Renal Cell Carcinoma by Activating Ferroptosis.
Aberrant expression of TRIM26 suppresses ferroptosis through regulating GPX4 protein stability in colorectal cancer.
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
Peroxisome-derived and liver-specific hydroxyacid oxidase 1-mediated hydrogen peroxide promotes ferroptosis by augmenting peroxisomal ROS.
Saikosaponin D Alleviates Liver Ischemia-Reperfusion Injury by Inhibiting Mitophagy-Associated Ferroptosis via the STAT3/PINK1 Pathway.
EGF-Upregulated lncRNA ESSENCE Promotes Colorectal Cancer Growth through Stabilizing CAD and Ferroptosis Defense.
CircRNA circ_0015278 induces ferroptosis in lung adenocarcinoma through the miR-1228/P53 axis.
TMEM105 modulates disulfidptosis and tumor growth in pancreatic cancer via the β-catenin-c-MYC-GLUT1 axis.
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Ferroptosis-Resistant Adipocytes Drive Keloid Pathogenesis via GPX4-Mediated Adipocyte-Mesenchymal Transition and Iron-Cystine Metabolic Communication.
Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells.
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Sakuranetin Prevents Acetaminophen-Induced Liver Injury via Nrf2-Induced Inhibition of Hepatocyte Ferroptosis.
Ghrelin alleviates high glucose-induced retinal microvascular endothelial cell injury by activating Nrf2/HO-1 pathway to inhibit ferroptosis.
Astragaloside IV Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis via the p53/SLC7A11/GPX4 Axis.
Carnosic acid attenuates diabetic retinopathy via the SIRT1 signaling pathway: neuroprotection and endothelial cell preservation.
Clara cell secretory protein 16 protects against PM2.5-induced ferroptosis in mouse lung epithelial cells in a concentration-dependent manner.
Ferroptosis-related genes as prognostic markers for survival and immunotherapy in triple-negative breast cancer: analysis of public databases and a single institution.
Resveratrol Induces Oxidative Stress and Downregulates GPX4 and xCT to Activate the Ferroptosis Pathway for Anti-Bladder Cancer Organoids.
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
SDCBP2 promotes tumor progression and is a novel ferroptosis-related prognostic biomarker in lung adenocarcinoma.
Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis.
Identification of ferroptosis-genes associated with pediatric inflammatory bowel disease bioinformatics and machine learning approaches.
The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study.
FGA modulates immune infiltration and tumor progression via SLC7A11/xCT-mediated disulfidptosis in the tumor microenvironment of lung adenocarcinoma.
Synergistic effect of regorafenib with aminoglycosides in ferroptosis-mediated liver injury.
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Hydrogen sulfide and ferroptosis inhibition underlies the dietary restriction-induced protection against cyclophosphamide cystitis.
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Metformin attenuates diabetic osteoporosis by suppressing ferroptosis via the AMPK/Nrf2 pathway.
Bioactive natural alkaloid 6-Methoxydihydrosanguinarine exerts anti-tumor effects in hepatocellular carcinoma cells via ferroptosis.
STOML2 inhibits sorafenib-induced ferroptosis in hepatocellular carcinoma via p-AKT signaling pathway.
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Asaraldehyde suppresses non-small cell lung cancer progression via ferroptosis induction and inhibition of PI3K-AKT signaling.
Ginsenoside Rh2 repressed the progression of prostate cancer through the mitochondrial damage induced by mitophagy and ferroptosis.
Bioinformatics and experimental unveiling of TIMP1 as a novel therapeutic target in colorectal cancer ferroptosis.
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer.
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Perillaldehyde synergizes with ferroptosis inducers to promote ferroptotic cell death in gastric cancer.
Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis.
POLR1A inhibits ferroptosis by regulating TFAM-mediated mitophagy and iron homeostasis.
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
NAT10-Mediated N4-Acetylation of SLC7A11 mRNA Promotes Hepatocellular Carcinoma Progression and Metastasis by Repressing Ferroptosis.
Rutin Alleviates Breast Cancer Resistance to Tamoxifen By Downregulating ABC Transporters, Inducing ROS Generation and Resetting Redox Status.
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Dimethylmalonate induces ferroptosis by inhibiting the SUCNR1/PI3K/HIF-1α/SLC7A11 signaling axis in triple-negative breast cancer.
Alexidine dihydrochloride enhances the sensitivity of human hepatocellular carcinoma to disulfidptosis via ATF4-DDIT3 activation.
β-elemene promotes ferroptosis to improve the sensitivity of imatinib in gastrointestinal stromal tumours by targeting N6AMT1.
Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinoma.
Formononetin enhances cisplatin chemotherapy sensitivity in osteosarcoma by inducing ferroptosis and reconstructing the immune microenvironment.
Neonatal necrotizing enterocolitis attenuates adult asthma via eosinophil ferroptosis.
ROS-Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling.
TMAO regulates OTUB1-mediated SLC7A11 stability to promote NAFLD progression.
FGF5 alleviates ferroptosis in renal tubular epithelial cells by inducing mitophagy under in vitro ischemia-reperfusion-like injury.
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
lncRNA CASC9 stabilizes MUC1 by binding to U2AF2 to inhibit cellular ferroptosis and alleviate LPS-induced cell injury.
Ulinastatin protects against cisplatin-induced ovarian damage via Nrf2/Keap1 pathway.
BRD-K20733377 inhibits ferroptosis and alleviates intervertebral disc degeneration via the STAT3/NFKB1 axis: a multiapproach study.
Extrachromosomal circular DNA drives ferroptosis and immunity in trophoblasts via the STING pathway in preeclampsia.
Mechanism of xihuang pill inhibition of SLC7A11 deubiquitination through downregulation of the OTUB1 to promote ferroptosis in triple-negative breast cancer.
Protecting the brain from stroke: Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection.
Peroxiredoxins as novel indicators in multiple myeloma associated with ferroptosis and immune infiltration.
Self-assembled cyanidin-3-O-glucoside nanoparticles alleviate inflammation and ferroptosis induced by PRRSV infection.
Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis.
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
Entospletinib alleviates acute liver injury and acute kidney injury by inhibiting ferroptosis.
TFAP2A-mediated Transcriptional Activation of ELMO1 Inhibits Ferroptosis and Promotes Esophageal Squamous Cell Carcinoma Progression.
Aloperine ameliorates radiation enteritis by driving the TAS2R138-PLCβ/GAPDH axis-mediated glucose metabolic reprogramming to inhibit ferroptosis in intestinal epithelial cells.
Mycophenolate mofetil inhibits ferroptosis by boosting autophagy to prevent pulmonary fibrosis.
Glycyrrhizic Acid Ameliorates LPS-Induced WI-38 Cell Inflammation, Oxidative Stress, and Ferroptosis via Targeting METTL14 in Infantile Pneumonia.
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
3D printed GelMA/HAMA based mechanical microenvironment boosted PDAC chemoresistance via NRF2-repressed ferroptosis.
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Ferredoxin 1-like maintains iron homeostasis and hepatoma cell survival.
CROT overactivation within peroxisomes confers chemoresistance to non-small cell lung cancer by targeting fatty acid oxidation-Nrf2-ferroptosis resistance axis.
5-HT regulates resistance to aumolertinib by attenuating ferroptosis in lung adenocarcinoma.
Panx3 mediates ferroptosis via the AKT/mTOR signaling pathway in oral squamous cell carcinoma.
IL-6/KIAA1429 promotes ferroptosis resistance in endometrial cancer through m6A modification of DDIT3.
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
TXNIP mediates ferroptosis in a bronchopulmonary dysplasia mouse model by regulating the SLC7A11/GPX4 pathway.
SLC25A10 promotes cisplatin resistance by inhibiting ferroptosis in cervical cancer.
Metabolic interplay between exogenous cystine and glutamine dependence in triple-negative breast cancer.
Molecular subtypes and prognostic signature rooted in disulfidptosis highlight tumor microenvironment in lung adenocarcinoma.
Integrated Multiomic Analysis Reveals the Therapeutic Potential of Danhong Injection in Mitigating Radiation-Induced Heart Disease by Modulating Ferroptosis.
Analysis of the Correlation Between Depression-like Behaviors and Lipid Peroxidation in the Prefrontal Cortex of Mice: The Impact of Early Life Stress.
Lycium barbarum polysaccharide alleviates osteoarthritis progression in mice DMM model by inhibiting chondrocytes ferroptosis and promoting the gut Lactobacillus/Alistipes ratio.
Mechanistic insights into the renoprotective effects of artesunate in cisplatin-induced acute kidney injury.
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis.
Atraric acid attenuates chronic intermittent hypoxia-induced lung injury by inhibiting ferroptosis through activation of the NRF2 pathway.
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Targeting ZNRF2-mediated SLC3A2 plasma membrane translocation enhances ferroptosis in lung adenocarcinoma.
ML385 increases ferroptosis via inhibiting Nrf2/HO-1 pathway to enhances the sensitivity of MCF-7 TAMR to tamoxifen.
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
SPINT2 inhibits NEDD4L-mediated ACSL4 ubiquitination to promote ferroptosis and suppress gallbladder cancer progression.
Structural characterization and functional role of SLC7A6 in GSSG transport and Ferroptosis regulation.
Bovine viral diarrhea virus E2 targets SLC3A2 to modulate lipid peroxidation for replication advantage.
Exosomal CagA induces macrophage polarization and ferroptosis by JAK1-2/STAT1 signaling pathway in Helicobacter pylori-associated gastritis.
Systemic aldehyde storm induced by allyl alcohol exposure results in extensive hepatic ferroptosis in Aldh2∗2 knock-in mice.
Botulinum Toxin Type A as a Therapeutic Agent in Epilepsy: Attenuation of Neuronal Ferroptosis and Cognitive Dysfunction.
Cardiomyocyte-specific knockout of Oip5-as1 exacerbates MI/R-induced ferroptosis via p62/KEAP1/NRF2 inhibition.
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
Downregulation of acetyl-CoA carboxylase induces ferroptosis and inhibits tumor growth in oral squamous cell carcinoma.
Sestrin2 Exerts a Novel Protective Effect Against LPS-Induced Ferroptosis via the Nrf2-SLC7A11-GPX4 Signaling Axis.
Taoren Honghua Jian improves ferroptosis-mediated myocardial damage following myocardial infarction via Nrf2-dependent enhancement of GPX4/FSP1.
Screening of key genes related to disulfidptosis in psoriasis based on the analysis of WGCNA.
NAT10-mediated lipid metabolic reprogramming drives EGFR-TKI resistance in non-small cell lung cancer via ac4C-dependent mRNA stabilization.
miR-188-5p accelerates intervertebral disc degeneration by mediating P4HB to regulate ferroptosis in nucleus pulposus cells.
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Unveiling tectorigenin: A novel ferroptosis inducer targeting EGFR in bladder cancer.
Jianpi Huayu decoction exerts antitumor effects in pancreatic cancer via SCD1-mediated lipid metabolism remodeling/ferroptosis axis.
Verbascoside (VB) Inhibits Ischemic Stroke Progression via Suppression of Cell Damage and Ferroptosis By Targeting LCN2/ALOX5/SLC7A11/GPX4 Expression.
Rescuing fertility: C-Phycocyanin prevents ovarian damage through NRF2-mediated ferroptosis pathways in polycystic ovary syndrome models.
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
BECN1 activator peptide Tat-beclin 1 promotes ferroptosis via the BECN1-SLC7A11 axis to inhibit NSCLC progression.
NCOA4-mediated ferroptosis conducive to EMT inhibition in colorectal cancer cells was achieved through the PI3K/AKT/mTOR pathway.
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer.
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment.
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Alkannin triggered apoptosis and ferroptosis in gastric cancer by suppressing lipid metabolism mediated by the c-Fos/SREBF1 axis.
Resveratrol Promotes Wound Healing by Enhancing Angiogenesis via Inhibition of Ferroptosis.
Human antigen R -mediated autophagy-related gene 3 methylation enhances autophagy-driven ferroptosis in Crohn's disease colitis.
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma.
METTL9 mediated N1-Histidine methylation of SLC39A7 confers ferroptosis resistance and inhibits adipogenic differentiation in mesenchymal stem cells.
Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.
Turning Waste into Treasure: Radiation Byproduct-Induced Fe(III)/Fe(II) Conversion for Efficient Ferroptosis to Improve Iodine-131-Based Transarterial Radioembolization for Liver Tumors.
NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis.
Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
The STEAP4 target NQO1 mediates colon tumorigenesis.
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury.
Platelet-Rich Plasma-Derived Exosome-Encapsulated Hydrogels Accelerate Diabetic Wound Healing by Inhibiting Fibroblast Ferroptosis.
TRIM21 knockdown alleviates hemorrhage induced hepatic ischemia reperfusion injury by suppressing ferroptosis-induced NETs.
Deciphering the Role of Ferroptosis in the Pathogenesis of Peripheral Artery Disease Myopathy.
Erythrocyte Membrane-Camouflaged Xanthohumol Nanoparticles Mitigate Doxorubicin-Induced Cardiotoxicity by Inhibiting Ferroptosis.
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
Integration of Bioinformatics and Machine Learning Strategies Identifies Ferroptosis and Immune Infiltration Signatures in Peri-Implantitis.
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.
Lactate Dehydrogenase A Is a Novel Positive Regulator of Vascular Smooth Muscle Cell Ferroptosis During Aortic Dissection.
USP13 facilitates a ferroptosis-to-autophagy switch by activation of the NFE2L2/NRF2-SQSTM1/p62-KEAP1 axis dependent on the KRAS signaling pathway.
p53 inhibits OTUD5 transcription to promote GPX4 degradation and induce ferroptosis in gastric cancer.
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways.
HMGB1 secretion by resveratrol in NSCLC: A pathway to ferroptosis-mediated platelet activation suppression.
The Lactate-Primed KAT8‒PCK2 Axis Exacerbates Hepatic Ferroptosis During Ischemia/Reperfusion Injury by Reprogramming OXSM-Dependent Mitochondrial Fatty Acid Synthesis.
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Moscatilin Induces Ferroptosis in Clear Cell Renal Cell Carcinoma via the JAK-STAT Signaling Pathway.
Induction of UBQLN1-mediated PGC1α stability by isoliensinine overcame hypoxia-induced resistance in liver cancer cells.
AC129507.1 is a ferroptosis-related target identified by a novel mitochondria-related lncRNA signature that is involved in the tumor immune microenvironment in gastric cancer.
ALPK1 signaling pathway activation by HMGB1 drives microglial pyroptosis and ferroptosis and brain injury after acute ischemic stroke.
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm.
Increased melanin induces aberrant keratinocyte - melanocyte - basal - fibroblast cell communication and fibrogenesis by inducing iron overload and ferroptosis resistance in keloids.
Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3.
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
Bisphenol F induces spermatogenic cell ferroptosis via FTO-mediated m6A regulation of FTH1.
Cyclic vinyl sulfones activate NRF2 to protect from oxidative stress-induced programmed necrosis.
Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's disease.
CBX3 promotes multidrug resistance by suppressing ferroptosis in colorectal carcinoma via the CUL3/NRF2/GPX2 axis.
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
IGF2BP1/AIFM2 axis regulates ferroptosis and glycolysis to drive hepatocellular carcinoma progression.
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Antitumor/anti-inflammatory effects/tissue healing as an all-in-one therapeutic strategy for nasopharyngeal carcinoma.
Mechanistic evaluation of a traditional herbal decoction in attenuating hepatic fibrosis via Nrf2/GPX4 pathway activation and ferroptosis inhibition.
Network pharmacology analysis reveals that coumestrol targets ZYX to inhibit ferroptosis and alleviate acute pancreatitis.
Mitigating PCOS progression: The protective effect of C-phycocyanin on ovarian granulosa cell pyroptosis via the NRF2/NLRP3/GSDMD pathway.
Cyanidin-3-O-glucoside mitigates Staphylococcus aureus-induced mastitis by suppressing inflammatory responses and Ferroptosis mediated by SESN2/Nrf2.
Circular Shear Printing of Spiral-Oriented CF-PP Components for Enhanced Mechanical Performance and Warp Mitigation.
CISD2 ameliorates heatstroke-associated early cognitive deficits by inhibiting ferroptosis and maintaining dendritic spine density in hippocampal neurons in mice.
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
Targeting SIX2 as a novel sensitization strategy of sorafenib treatment on advanced hepatocellular carcinoma through modulating METTL9-SLC7A11 axis.
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
BTN3A2 interacted with MFGE8 to alleviate preeclampsia by promoting ferroptosis and inhibiting angiogenesis.
Ferulic acid/GRB2/NF-κB signaling pathway that alleviates ferroptosis-induced apoptosis of nucleus pulposus cells is a potential mechanism for intervertebral disc degeneration.
MGST1 Inhibits Sevoflurane-Induced Ferroptosis and Activates the Wnt Pathway in HT22 Cells.
Aerobic Exercise Activates Fibroblast Growth Factor 21 and Alleviates Cardiac Ischemia/Reperfusion-induced Neuronal Oxidative Stress and Ferroptosis in Paraventricular Nucleus.
Carfilzomib promotes Iodine-125 seed radiation-induced apoptosis, paraptosis, and ferroptosis in esophageal squamous cell carcinoma by aggravating endoplasmic reticulum stress.
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
SPATA2/CYLD Pathway-Dependent Deubiquitylation of p53 Promotes Ferroptosis in Rat Heart After Ischaemia/Reperfusion Through Suppression of SLC7A11.
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Identification of FADS2 as a Contributor of Ferroptosis Escape in Bladder Cancer.
Methionine sulfoxide reductase A deficiency aggravated ferroptosis in LPS-induced acute kidney injury by inhibiting the AMPK/NRF2 axis and activating the CaMKII/HIF-1α pathway.
Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity.
Apatinib combined with paclitaxel suppresses synergistically TNBC progression through enhancing ferroptosis susceptibility regulated SLC7A11/GPX4/ACSL4 axis.
Exploring the molecular mechanisms through which overexpression of TET3 alleviates liver fibrosis in mice via ferroptosis in hepatic stellate cells.
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
Targeting myeloid differentiation protein 2 ameliorates rheumatoid arthritis by inhibiting inflammation and ferroptosis via MAPK and NF-κB signaling pathways.
Transcription factor TCF3 promotes bladder cancer development via TMBIM6-Ca(2+)-dependent ferroptosis.
Cadmium Inhibits Proliferation of Human Bronchial Epithelial BEAS-2B Cells Through Inducing Ferroptosis via Targeted Regulation of the Nrf2/SLC7A11/GPX4 Pathway.
Ponicidin triggered ferroptosis in esophageal squamous cell carcinoma by suppressing the SLC7A11/Glutathione/GPX4 signalling axis.
Caffeic acid phenethyl ester protects renal tubular epithelial cells against ferroptosis in diabetic kidney disease via restoring PINK1-mediated mitophagy.
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Large-sized polystyrene microplastics induce oxidative stress in AML12 cells.
The SDF-1α/MTDH axis inhibits ferroptosis and promotes the formation of anti-VEGF-resistant choroidal neovascularization by facilitating the nuclear translocation of SREBP1.
Irisin prevents liver injury during exhausting physical activity by suppressing ferroptosis via Nrf2/GPX4 signaling.
Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways.
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
The role of SLC7A11 in arsenite-induced oncogenic phenotypes of human bronchial epithelial cells: A metabolic perspective.
TBBPA-BDBPE induces ferroptosis in trophoblasts through chaperone-mediated autophagy of GPX4.
SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway.
Leveraging diverse cell death patterns in osteosarcoma patients and identification of the function of FADS2 in osteosarcoma cells.
cDTL contributes to breast cancer progression through regulating redox homeostasis via affecting the function of system xc().
LRRC45 accelerates bladder cancer development and ferroptosis inhibition via stabilizing NRF2 by competitively KEAP1 interaction.
Lipoxin A4 suppresses neutrophil extracellular traps formation through the FPR2-dependent regulation of METTL3 in ischemic stroke.
The synergistic protective effects of paeoniflorin and β-ecdysterone against cardiac hypertrophy through suppressing oxidative stress and ferroptosis.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period.
Bardoxolone methyl triggers Ferroptosis in cardiomyocytes.
Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.
Enhanced glycolysis-derived lactate promotes microglial activation in Parkinson's disease via histone lactylation.
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Targeting estrogen-regulated system x(c)(-) promotes ferroptosis and endocrine sensitivity of ER+ breast cancer.
Comprehensive Pan-Cancer Analysis and Functional Studies Reveal SLC2A6 as a Ferroptosis Modulator in Hepatocellular carcinoma.
Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma.
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
ZC3H13 may participate in the ferroptosis process of sepsis-induced cardiomyopathy by regulating the expression of Pnn and Rbm25.
Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms.
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Trehalose Inhibits ferroptosis Through Activating SIRT3/SOD2 Signaling Axis and Alleviates Brain Injury After Traumatic Brain Injury.
CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis.
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1.
Platycodin D2 Mediates Incomplete Autophagy and Ferroptosis in Breast Cancer Cells by Regulating Mitochondrial ROS.
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma.
Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis.
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Ferristatin II protects nucleus pulposus against degeneration through inhibiting ferroptosis and activating HIF-1α pathway mediated mitophagy.
Hypoxia-Regulated CD44 and xCT Expression Contributes to Late Postoperative Epilepsy in Glioblastoma.
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis.
GLS1-mediated glutamine metabolism mitigates oxidative stress-induced matrix degradation, ferroptosis, and senescence in nucleus pulposus cells by modulating Fe(2+) homeostasis.
Lactate-Fueled Theranostic Nanoplatforms for Enhanced MRI-Guided Ferroptosis Synergistic with Immunotherapy of Hepatocellular Carcinoma.
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
Puerarin reduces susceptibility to ventricular arrhythmias and inhibits ferroptosis via Sirt1/Nrf2 signaling in high-fat-diet rats.
Ferroptosis suppressor protein 1 regulated oligodendrocytes ferroptosis rescued by idebenone in spinal cord injury.
ZBTB20 promotes ferroptosis through inhibiting TMEM109 expression in glioblastoma cells.
Targeting SLC7 A11 Ameliorates Ulcerative Colitis by Promoting Efferocytosis Through the ERK1/2 Pathway.
Maresin-1 alleviates sepsis-induced acute kidney injury by inhibiting ferroptosis via the Nrf2/HO-1/Gpx4 signaling pathway.
4-Methoxylonchocarpin protects against cisplatin induced acute kidney injury via regulating ferroptosis.
Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production.
Network pharmacology combined with experiments to explore the molecular mechanism of Jiawei Erzhi pill protects against atherosclerosis by inhibiting ferroptosis.
Development and Validation of a New Prediction Criteria for Neoadjuvant Chemotherapy Response in Locally Advanced Gastric Cancer Based on Ferroptosis-Related Biomarkers.
Lactoferrin-cyanidin-3-glucoside nanoparticles alleviate inflammation and oxidative stress via Sesn2/Nrf2 activation in mastitis.
Injectable magnetic hydrogel induces multi-programmed cell death and deep tumor regression in magnetic hyperthermia therapy in hepatocellular carcinoma.
Integrated transcriptome profiling and in vitro analysis reveals MLN4924's role in inducing ferroptosis in acute myeloid leukemia.
FXR/SMAD3 Regulates SOX9 to Inhibit Hepatic Fibrosis in Biliary Atresia via Inhibiting Ferroptosis of Hepatic Stellate Cells.
Astaxanthin suppress ferroptosis through the Akt1-FoxO3a signaling pathway to alleviates brain injury after intracerebral hemorrhage.
HOXA13 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating SLC7A11 and SLC3A2.
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
CBX2 and EZH2 cooperatively contribute to 5-Fu resistance in gastric cancer by suppressing ferroptosis via trimethylation of H3k27.
Inhibition of EgRad50 leads to impaired DNA repair in Echinococcus granulosus sensu stricto.
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway.
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
MiR-122-5p modulates ferroptosis via SLC7A11: A potential therapeutic target in autoimmune hepatitis.
Echinacoside as a Novel Ferroptosis Inducer in Hepatocellular Carcinoma: Mechanistic Insights from TP53/SLC7A11/GPX4 Pathway Modulation.
Super-enhancers mediates SLC7A11 via FOXA1 to regulate disulfidptosis in prostate cancer.
Cytochrome c Oxidase Subunit COX4-1 Reprograms Erastin-Induced Cell Death from Ferroptosis to Apoptosis: A Transmitochondrial Study.
Tip60-HDAC8-SMURF2-mediated β-TrCP1 degradation is a key mechanism for hypoxia-induced cell death and tissue injury.
NEDD4 suppresses ferroptosis in lung ischemia-reperfusion injury by ubiquitinating and degrading SLC1A5.
Ferroptosis inhibition via the ROS-GPX4 axis drives microplastic-induced malignant progression of nasopharyngeal carcinoma.
Targeting intrinsically disordered nuclear protein 1 (NUPR1) with single-domain antibodies alleviates triple-negative breast cancer (TNBC) progression in vivo.
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC.
Auranofin facilitates gemcitabine sensitivity by regulating TXNRD1-related ferroptosis in pancreatic ductal adenocarcinoma.
RBMS2 mediates SLC7A11 transcription-translation to regulate ferroptosis in colorectal cancer.
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Nrg4 Secreted by Brown Adipose Tissue Suppresses Ferroptosis of Sepsis-Induced Liver Injury.
PRMT5 K240lac confers ferroptosis resistance via ALKBH5/SLC7A11 axis in colorectal cancer.
SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.
METTL3 increases ferroptosis resistance to facilitate the tumor-like features of rheumatoid arthritis synovial fibroblasts through enhancing SLC7A11 mRNA stability in an m6A-IGF2BP2-dependent manner.
A novel FTO-targeting nanodrug induces disulfidptosis and ameliorates the suppressive tumor immune environment to treat uveal melanoma.
A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis.
Salinomycin inhibits SREBP1 to sensitize ferroptosis and ameliorate sorafenib resistance in clear cell renal cell carcinoma.
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
WTAP Dysregulation Mediates HLF-m6A Modification to Inhibit Trophoblast Ferroptosis in Preeclampsia.
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
Erchen decoction alleviates silicosis by attenuating ferroptosis and fibrosis in alveolar macrophages via modulating the P53/HMOX1 pathway.
Bu-Yang decoction attenuates OVX-induced sarcopenia by upregulating CXCR4 to suppress GPX4-mediated ferroptosis.
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer.
A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma.
Sulfasalazine induces ferroptosis in osteosarcomas by regulating Nrf2/SLC7A11/GPX4 signaling axis.
Synthesis of USP5-IN-1 derivatives as novel USP5 inhibitors with potent activity against cholangiocarcinoma cells.
Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection.
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Key role of the CSE/transsulfuration pathway in macrophage phenotypic change under iron overload.
Decreased gut microbiome-derived indole-3-propionic acid mediates the exacerbation of myocardial ischemia/reperfusion injury following depression via the brain-gut-heart axis.
Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux.
Generation of Myeloid-Specific Bmal1 Knockout Mice and Identification of Bmal1-Regulated Ferroptosis in Macrophages.
Regulatory factor X1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by transcriptional regulation of BECN1.
Nrf2 alleviates acute ischemic stroke induced ferroptosis via regulating xCT/GPX4 pathway.
β-Diketone Functionalized Microspheres Chelate Reactive Iron via Metal Coordination for Cartilage Repair.
Yinaoxin granule alleviates cerebral ischemia-reperfusion injury by ferroptosis inhibition through Nrf2 pathway activation.
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Dapagliflozin alleviates high-fat-induced obesity cardiomyopathy by inhibiting ferroptosis.
MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non-Small Cell Lung Cancer.
Short-term effects of subacute ruminal acidosis on ferroptosis and iron metabolism in the livers of lactating sheep fed a high-grain diet.
Tanshinone IIA Ameliorates Myocardial Ischemia-Reperfusion Injury via Activating HDAC1-Repressed Nrf2-xCT/Gpx4/HO-1 Axis.
The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication.
Mechanism of Mitophagy to Protect Yak Kidney from Hypoxia-Induced Fibrosis Damage by Regulating Ferroptosis Pathway.
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Identification of HCAR1 as a ferroptosis-related biomarker of gastric cancer based on a novel ferroptosis-related prognostic model and in vitro experiments.
TAZ/NRF2 positive feedback loop contributes to proliferation in bladder cancer through antagonistic ferroptosis.
Vaccarin alleviates renal ischemia-reperfusion injury by inhibiting inflammation and ferroptosis.
Saponins from Astragalus membranaceus (Fisch.) Bge Alleviated Neuronal Ferroptosis in Alzheimer's Disease by Regulating the NOX4/Nrf2 Signaling Pathway.
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
RNF128 promotes gastric cancer progression by inhibiting autophagy-dependent ferroptosis through Beclin1 ubiquitination.
FADS2 inhibits colorectal cancer cell proliferation by regulating ferroptosis through SLC7A11/GPX4.
Artesunate induces ferroptosis in osteosarcoma through NCOA4-mediated ferritinophagy.
TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer.
CircMFN2/miR-361-3p/ELK1 feedback loop promotes glutaminolysis and the progression of hepatocellular carcinoma.
Protocadherin 17 weakens the lenvatinib resistance of liver cancer through inducing ferroptosis.
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Cell Cycle-Related Centromere Protein F Deficiency Suppresses Ovarian Cancer Cell Growth by Inducing Ferroptosis.
Triptolide Attenuates Renal Slit Diagram to Tight Junction Transition in Diabetic Kidney Disease by Regulating Nrf2-Ferroptosis Pathway.
Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice.
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis.
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Gandouling Regulates Ferroptosis and Improves Neuroinflammation in Wilson's Disease Through the LCN2/NLRP3 Signaling Pathway.
The High Expression of SLC7A11 and GPX4 are Significantly Correlated with β-Catenin in Colorectal Cancer.
miR-141-3p promotes paclitaxel resistance by attenuating ferroptosis via the Keap1-Nrf2 signaling pathway in breast cancer.
NCAPD3-mediated ferroptosis of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells.
Dissecting the functions and regulatory mechanisms of disulfidoptosis-related RPN1 in pan-cancer: modulation of immune microenvironment and cellular senescence.
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
Hydrogen sulfide protects against toxicant acrolein-induced ferroptotic cell death in Sertoli cells.
Multidimensional role of adapalene in regulating cell death in multiple myeloma.
LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway.
Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis.
Exosomal miR-223-3p from bone marrow mesenchymal stem cells targets HDAC2 to downregulate STAT3 phosphorylation to alleviate HBx-induced ferroptosis in podocytes.
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer.
EIF4A3-induced circ_0022382 promotes breast cancer cell progression through the let-7a-5p/PI3K/AKT/mTOR signaling pathway and SLC7A11 axis.
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Unveiling the mechanism of photothermal therapy in acne man-agement: targeting sebaceous gland ferroptosis via umbilical cord mesenchymal stem cell membrane-encapsulated Au-Ag-PDA.
RAB17 promotes endometrial cancer progression by inhibiting TFRC-dependent ferroptosis.
Aldo-Keto reductase 1C3 reduces myocardial cell damage after acute myocardial infarction by activating the Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2-antioxidant response element pathway to inhibit ferroptosis.
Ursolic Acid Ameliorates Alcoholic Liver Injury through Attenuating Oxidative Stress-Mediated Ferroptosis and Modulating Gut Microbiota.
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
Oxidative stress induces ferroptosis in tendon stem cells by regulating mitophagy through cGAS-STING pathway.
Downregulation of the (pro)renin receptor alleviates ferroptosis-associated cardiac pathological changes via the NCOA 4-mediated ferritinophagy pathway in diabetic cardiomyopathy.
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
Borna disease virus 1 induces ferroptosis, contributing to lethal encephalitis.
Targeting GPX4-mediated ferroptosis protection sensitizes BRCA1-deficient cancer cells to PARP inhibitors.
Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response.
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway.
NAT10 inhibition promotes ac4C-dependent ferroptosis to counteract sorafenib resistance in nasopharyngeal carcinoma.
Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1.
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
TRIB3 inhibition by palbociclib sensitizes prostate cancer to ferroptosis via downregulating SOX2/SLC7A11 expression.
Hyperbaric Oxygen Improves Cognitive Impairment Induced by Hypoxia via Upregulating the Expression of Oleic Acid and MBOAT2 of Mice.
A respiratory Streptococcus strain inhibits Acinetobacter baumannii from causing inflammatory damage through ferroptosis.
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Succinylated Type I Collagen Regulates Ferroptosis to Attenuate Skin Photoaging.
The Protective Effects of Polygala tenuifolia and Tenuifolin on Corticosterone-Evoked Ferroptosis, Oxidative Stress, and Neuroinflammation: Insights from Molecular Dynamics Simulations and In Vitro Experiments.
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells.
The protective role of RACK1 in hepatic ischemia‒reperfusion injury-induced ferroptosis.
Metformin suppresses metabolic dysfunction-associated fatty liver disease by ferroptosis and apoptosis via activation of oxidative stress.
CBR-470-1 protects against cardiomyocyte death in ischaemia/reperfusion injury by activating the Nrf2-GPX4 cascade.
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Isoliquiritigenin alleviates SLC7A11-mediated efferocytosis inhibition to promote wounds healing in diabetes.
Licochalcone A decreases cancer cell proliferation and enhances ferroptosis in acute myeloid leukemia through suppressing the IGF2BP3/MDM2 cascade.
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma.
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
Echinacoside Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Inhibiting Ferroptosis via Nrf2/HMOX1 Pathway.
Matrine protects against experimental autoimmune encephalomyelitis through modulating microglial ferroptosis.
Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2.
KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11.
NEDD4L contributes to ferroptosis and cell growth inhibition in esophageal squamous cell carcinoma by facilitating xCT ubiquitination.
Huperzine A protected against ferroptosis via activating PI3K/Akt signaling in lipopolysaccharide induced acute lung injury.
Total extracts from Abelmoschus manihot (L.) alleviate radiation-induced cardiomyocyte ferroptosis via regulating redox imbalances mediated by the NOX4/xCT/GPX4 axis.
Carthamin yellow alleviates dextran sodium sulfate-induced ulcerative colitis by repairing the intestinal barrier and activating the Nrf2/GPX4 axis.
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
HIF-2α/TFR1 mediated iron homeostasis disruption aggravates cartilage endplate degeneration through ferroptotic damage and mtDNA release: A new mechanism of intervertebral disc degeneration.
N-acetylcysteine Protects Against Myocardial Ischemia-Reperfusion Injury Through Anti-ferroptosis in Type 1 Diabetic Mice.
Co-exposure of arsenic and polystyrene-nanoplastics induced kidney injury by disrupting mitochondrial homeostasis and mtROS-mediated ferritinophagy and ferroptosis.
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Quercetin Inhibits Neuronal Pyroptosis and Ferroptosis by Modulating Microglial M1/M2 Polarization in Atherosclerosis.
Non-cytotoxic nanomolar concentration of arctigenin protects neuronal cells from chemotherapy-induced ferroptosis by regulating SLC7A11-cystine-cysteine axis.
Anti-ferroptosis exosomes engineered for targeting M2 microglia to improve neurological function in ischemic stroke.
Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma.
Lizhong decoction ameliorates ulcerative colitis by inhibiting ferroptosis of enterocytes via the Nrf2/SLC7A11/GPX4 pathway.
Pharmacological inhibition of p300 ameliorates steatosis, inflammation, and fibrosis in mice with non-alcoholic steatohepatitis.
IL-1α facilitates GSH synthesis to counteract oxidative stress in oral squamous cell carcinoma under glucose-deprivation.
Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance.
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Circular RNA ANKIB1 alleviates hypoxia-induced cardiomyocyte injury by modulating miR-452-5p/SLC7A11 axis.
Boosting the synergism between cancer ferroptosis and immunotherapy via targeted stimuli-responsive liposomes.
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Ferroptosis in Osteocytes as a Target for Protection Against Postmenopausal Osteoporosis.
VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Pentoxifylline protects against cerebral ischaemia-reperfusion injury through ferroptosis regulation via the Nrf2/SLC7A11/GPX4 signalling pathway.
Mesenchymal stem cells inhibit ferroptosis by activating the Nrf2 antioxidation pathway in severe acute pancreatitis-associated acute lung injury.
Cell-Cycle-related Protein Centromere Protein F Deficiency Inhibits Cervical Cancer Cell Growth by Inducing Ferroptosis Via Nrf2 Inactivation.
Widespread S-persulfidation in activated macrophages as a protective mechanism against oxidative-inflammatory stress.
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells.
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Botulinum toxin A attenuates osteoarthritis development via inhibiting chondrocyte ferroptosis through SLC7Al1/GPX4 axis.
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis.
MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway.
Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload.
α-Ketoglutarate alleviates osteoarthritis by inhibiting ferroptosis via the ETV4/SLC7A11/GPX4 signaling pathway.
ERRFI1 exacerbates hepatic ischemia reperfusion injury by promoting hepatocyte apoptosis and ferroptosis in a GRB2-dependent manner.
HMOX1 regulates ferroptosis via mic14 and its impact on chemotherapy resistance in small-cell lung cancer.
Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway.
HDAC inhibitors activate lipid peroxidation and ferroptosis in gastric cancer.
DDX39B protects against sorafenib-induced ferroptosis by facilitating the splicing and cytoplasmic export of GPX4 pre-mRNA in hepatocellular carcinoma.
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
Quercetin inhibits neuronal Ferroptosis and promotes immune response by targeting lipid metabolism-related gene PTGS2 to alleviate breast cancer-related depression.
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
Selenomethionine protects the liver from dietary deoxynivalenol exposure via Nrf2/PPARγ-GPX4-ferroptosis pathway in mice.
RETRACTED ARTICLE: Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway.
Arvanil induces ferroptosis of hepatocellular carcinoma by binding to MICU1.
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma.
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Niujiao Dihuang Jiedu decoction promotes SLC7A11 m5C methylation modification against ferroptosis in acute-on-chronic liver failure.
Polyphyllin I induced ferroptosis to suppress the progression of hepatocellular carcinoma through activation of the mitochondrial dysfunction via Nrf2/HO-1/GPX4 axis.
Chrysophanol induces apoptosis and ferroptosis of gastric cancer cells by targeted regulation of mTOR.
Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.
SNRPB promotes the progression of hepatocellular carcinoma via regulating cell cycle, oxidative stress, and ferroptosis.
In silico prediction and experimental validation to reveal the protective mechanism of Puerarin against excessive extracellular matrix accumulation through inhibiting ferroptosis in diabetic nephropathy.
Pan-Cancer Analysis Reveals Disulfidoptosis-Associated Genes as Promising Immunotherapeutic Targets: Insights Gained from Bulk Omics and Single-Cell Sequencing Validation.
Sodium Butyrate Alleviates Free Fatty Acid-Induced Steatosis in Primary Chicken Hepatocytes via Regulating the ROS/GPX4/Ferroptosis Pathway.
LncRNA MEG3 suppresses erastin-induced ferroptosis of chondrocytes via regulating miR-885-5p/SLC7A11 axis.
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma.
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers.
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
In situ generation of hybrid alginate hydrogels for enhanced breast tumor ferrotherapy through multiplex magnifying redox imbalances.
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression.
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma.
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
A novel tsRNA-5008a promotes ferroptosis in cardiomyocytes that causes atrial structural remodeling predisposed to atrial fibrillation.
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms.
PRKN-mediated the ubiquitination of IQGAP3 regulates cell growth, metastasis and ferroptosis in early-onset colorectal cancer.
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Sirt6 overexpression relieves ferroptosis and delays the progression of diabetic nephropathy via Nrf2/GPX4 pathway.
β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis.
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Puerarin alleviates symptoms of preeclampsia through the repression of trophoblast ferroptosis via the CREB/HO-1 pathway.
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Suyin Detoxification Granule alleviates trimethylamine N-oxide-induced tubular ferroptosis and renal fibrosis to prevent chronic kidney disease progression.
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis.
Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation.
To explore the protective mechanism of promethazine against hippocampal neuron injury based on network pharmacology and experimental verification.
Gypenoside A-loaded mPEG-PLGA nanoparticles ameliorate high-glucose-induced retinal microvasculopathy by inhibiting ferroptosis.
Simvastatin induces ferroptosis and activates anti-tumor immunity to sensitize anti-PD-1 immunotherapy in microsatellite stable gastric cancer.
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
Inhibition of miR-9-3p facilitates ferroptosis by activating SAT1/p53 pathway in lung adenocarcinoma.
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
Protective Effects of Tormentic Acid on Unilateral Ureteral Obstruction-Induced Renal Injury, Inflammation, and Fibrosis: A Comprehensive Approach to Reducing Oxidative Stress, Apoptosis, and Ferroptosis.
Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes.
REV-ERBα inhibitor rescues MPTP/MPP(+)-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway.
High glucose elevates intracellular calcium level and induces ferroptosis in glomerular endothelial cells through the miR-223-3p/ITPR3 pathway.
Pharmacodynamic insights into maresin 1: Enhancing flap viability via the keap1/Nrf2 axis to control ROS-driven apoptosis and ferroptosis.
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells via ATP6V0D1-mediated ABCB1 inhibition.
Curcumin inhibits PAT-induced renal ferroptosis via the p62/Keap1/Nrf2 signalling pathway.
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway.
Glutamine Mitigates Oxidative Stress-Induced Matrix Degradation, Ferroptosis, and Pyroptosis in Nucleus Pulposus Cells via Deubiquitinating and Stabilizing Nrf2.
ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair.
Baicalin protects against hepatocyte injury caused by aflatoxin B(1) via the TP53-related ferroptosis Pathway.
SLC7A11 and the glutathione pathway as novel prognostic markers in resectable pancreatic ductal adenocarcinoma: A metabolomics study of clinical specimens.
Nanoliposomes Encapsulated Rapamycin/Resveratrol to Induce Apoptosis and Ferroptosis for Enhanced Colorectal Cancer Therapy.
Effects on Iron Metabolism and System Xc- /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells.
Natural Product Auraptene Targets SLC7A11 for Degradation and Induces Hepatocellular Carcinoma Ferroptosis.
PRMT5-mediated FUBP1 methylation accelerates prostate cancer progression.
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway.
Phosphoproteomics Reveals Novel Insights into the Pathogenesis and Identifies New Therapeutic Kinase Targets of Ulcerative Colitis.
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53-P21/Nrf2 activation in a HuR-dependent m6A manner.
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy.
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Copper Exposure Induced Chicken Hepatotoxicity: Involvement of Ferroptosis Mediated by Lipid Peroxidation, Ferritinophagy, and Inhibition of FSP1-CoQ10 and Nrf2/SLC7A11/GPX4 Axis.
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen.
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Vitamin D Promotes Ferroptosis in Colorectal Cancer Stem Cells via SLC7A11 Downregulation.
Loss of Lactate/Proton Monocarboxylate Transporter 4 Induces Ferroptosis via the AMPK/ACC Pathway and Inhibition of Autophagy on Human Bladder Cancer 5637 Cell Line.
Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination.
miR-432-5p Inhibits the Ferroptosis in Cardiomyocytes Induced by Hypoxia/Reoxygenation via Activating Nrf2/SLC7A11 Axis by Degrading Keap1.
GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver Failure.
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Solute Carrier Family 7 Member 11 (SLC7A11) is a Potential Prognostic Biomarker in Uterine Corpus Endometrial Carcinoma.
AhR Promotes the Development of Non-small cell lung cancer by Inducing SLC7A11-dependent Antioxidant Function.
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression.
Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel.
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Paraquat-induced ferroptosis suppression via NRF2 expression regulation.
CAPG interference induces apoptosis and ferroptosis in colorectal cancer cells through the P53 pathway.
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis.
Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway.
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
The clinical predictive value and regulation mechanism of microRNA-188-5p in contrast-induced acute kidney injury.
2, 2-dimethylthiazolidine hydrochloride protects against experimental contrast-induced acute kidney injury via inhibition of tubular ferroptosis.
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis.
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
IRF1 suppresses colon cancer proliferation by reducing SPI1-mediated transcriptional activation of GPX4 and promoting ferroptosis.
Ferroptosis contributes to cyclophosphamide-induced hemorrhagic cystitis.
Qi-Shen-Tang alleviates retinitis pigmentosa by inhibiting ferroptotic features via the NRF2/GPX4 signaling pathway.
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
Inhibition of ferroptosis alleviates chronic unpredictable mild stress-induced depression in mice via tsRNA-3029b.
Drug Repurposing-Based Brain-Targeting Self-Assembly Nanoplatform Using Enhanced Ferroptosis against Glioblastoma.
Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the NRF2 pathway.
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Identification of disulfidptosis-related subtypes and development of a prognosis model based on stacking framework in renal clear cell carcinoma.
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
Vitamin D Attenuates Ulcerative Colitis by Inhibiting ACSL4-Mediated Ferroptosis.
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Metabolomics analysis reveals cytotoxic effects of ouabain towards psoriatic keratinocytes via impairment of glutathione metabolism.
p53 Activates the Lipoxygenase Activity of ALOX15B via Inhibiting SLC7A11 to Induce Ferroptosis in Bladder Cancer Cells.
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Engineering MMP-2 Activated Nanoparticles Carrying B7-H3 Bispecific Antibodies for Ferroptosis-Enhanced Glioblastoma Immunotherapy.
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Identification of a ferroptosis-related gene signature for prognosis prediction in colorectal cancer patients and relationship with vitamin D.
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Mechanism of ferroptosis in a rat model of premature ovarian insufficiency induced by cisplatin.
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma.
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Mesenchymal stem cell-derived exosomal microRNA-367-3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2.
Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis.
Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.
Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Graphdiyne nanoplatforms for photothermal-ferroptosis combination therapy against glioblastoma.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Artemisia argyi H.Lév. & Vaniot essential oil induces ferroptosis in pancreatic cancer cells via up-regulation of TFR1 and depletion of γ-glutamyl cycle.
Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.
Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway.
The effect of ferroptosis - related proteins and histone deacetylases1 on neoadjuvant chemotherapy in breast cancer.
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Medroxyprogesterone acetate-resistant endometrial cancer cells are susceptible to ferroptosis inducers.
m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis.
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.
DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson's disease.
Treatment with paraquat affects the expression of ferroptosis-related genes.
Sodium Butyrate Induces CRC Cell Ferroptosis via the CD44/SLC7A11 Pathway and Exhibits a Synergistic Therapeutic Effect with Erastin.
Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells.
MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells.
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
pH-sensitive molybdenum (Mo)-based polyoxometalate nanoclusters have therapeutic efficacy in inflammatory bowel disease by counteracting ferroptosis.
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Feasibility of [(18)F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type KRAS Colorectal Cancer.
Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma.
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway.
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway.
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
The ubiquitin-specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression.
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis.
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Inhibition of Connexin43 Improves the Recovery of Spinal Cord Injury Against Ferroptosis via the SLC7A11/GPX4 Pathway.
A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Targeting the Na(+)/K(+) ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity.
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury.
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Single-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis.
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts.
Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage.
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Cardiac Fibroblasts Promote Ferroptosis in Atrial Fibrillation by Secreting Exo-miR-23a-3p Targeting SLC7A11.
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene SLC7A11 as a Prognostic Biomarker for Cancer.
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Ferrostatin-1 Ameliorates Liver Dysfunction via Reducing Iron in Thioacetamide-induced Acute Liver Injury in Mice.
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Induction of Ferroptosis by Ophiopogonin-B Through Regulating the Gene Signature AURKA in NSCLC.
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics.
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
ARPC1A is regulated by STAT3 to inhibit ferroptosis and promote prostate cancer progression.
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Targeting NRF2 Sensitizes Esophageal Adenocarcinoma Cells to Cisplatin through Induction of Ferroptosis and Apoptosis.
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia-reperfusion injury after cardiac surgery with cardiopulmonary bypass.
Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway.
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling.
PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma.
Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors.
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis.
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma.
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Functional role of the SLC7A11-AS1/xCT axis in the development of gastric cancer cisplatin-resistance by a GSH-dependent mechanism.
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Action of the Nrf2/ARE signaling pathway on oxidative stress in choroid plexus epithelial cells following lanthanum chloride treatment.
CEMIP promotes extracellular matrix-detached prostate cancer cell survival by inhibiting ferroptosis.
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis.
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ(1-42)-induced Alzheimer's disease mice and glutamate-injured HT22 cells.
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
C8orf76 Modulates Ferroptosis in Liver Cancer via Transcriptionally Up-Regulating SLC7A11.
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m(6)A modification.
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
Dihydroquercetin suppresses cigarette smoke induced ferroptosis in the pathogenesis of chronic obstructive pulmonary disease by activating Nrf2-mediated pathway.
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
The dual role of p62 in ferroptosis of glioblastoma according to p53 status.
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
A multi-omic landscape of steatosis-to-NASH progression.
Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis.
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
An all-in-one biomimetic iron-small interfering RNA nanoplatform induces ferroptosis for cancer therapy.
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination.
Anti-PD-L1 DNAzyme Loaded Photothermal Mn(2+) /Fe(3+) Hybrid Metal-Phenolic Networks for Cyclically Amplified Tumor Ferroptosis-Immunotherapy.
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Construction and Validation of a Combined Ferroptosis and Hypoxia Prognostic Signature for Hepatocellular Carcinoma.
Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT.
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner.
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis.
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis.
Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms.
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.
Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma.
Discovery of a novel ferroptosis inducer-talaroconvolutin A-killing colorectal cancer cells in vitro and in vivo.
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Jiang J, Xu Y, Dai T, Chen J, Li S, Meng Q
PloS one 2026;21(2):e0342242
PloS one 2026;21(2):e0342242
Aloperine Induces Ferroptosis of Colorectal Cancer Cells via the Nrf2 Pathway.
An J, Tian L, Wang R, Ma D, Song J, Yuan R, Wu J, Bu Y, Wang J
OncoTargets and therapy 2026;19:575500
OncoTargets and therapy 2026;19:575500
Actinidia chinensis Planch Root extracts trigger ferroptosis in colorectal cancer via the p53/SLC7A11/GPX4 axis.
Ma C, Chen R, Wang H, Qiu K, Xia Q, Yang S, Wang J, Cheng Z, Cui W, Lu J, Duan S
Frontiers in pharmacology 2026;17:1724983
Frontiers in pharmacology 2026;17:1724983
Epigenetic activation of SLC7A11 defines a ferroptosis-immune axis and enables robust DNA methylation-based diagnosis of lung squamous cell carcinoma.
Lu HP, Nong K, Pang L, Tang Y, Li Q, Chen Z, Xiao L, Zhu L, Li D, Chen Y, Chen G, Ling J, Li J, Chen G, Dang YW
PeerJ 2026;14:e20686
PeerJ 2026;14:e20686
The contribution of ferroptosis to the epithelial-mesenchymal transition phenotype in models of age-related macular degeneration.
Yang X, Xu W, Xie H, Guo X, Zhu F, Xing Y, Chen C
Frontiers in cell and developmental biology 2026;14:1718715
Frontiers in cell and developmental biology 2026;14:1718715
Monitoring early micro-oxidation under refrigeration: iron and oxidative markers predict quality loss in grass carp.
Xiong X, Feng R, Zhang H, Ding N, Zhuang S, Tan Y, Ma H, Hong H, Luo Y
Current research in food science 2026;12:101307
Current research in food science 2026;12:101307
ETV4 transcriptionally activates STAT6 to inhibit ferroptosis and promote immune escape in thyroid cancer.
Zong W, Wang Y, Xu B
Endocrine research 2026 May;51(2):78-92
Endocrine research 2026 May;51(2):78-92
Ginsenoside Rb2 Attenuates Microvascular Endothelial Stress Injury by Mediating Mitochondrial Pathway Pyroptosis via the DNA-PKcs-SIRT5 Axis.
Pu X, Yan Z, Liu J, Wang Y, Guan X, Wu Q, Zhang Q, Liu R, Chang X
Phytotherapy research : PTR 2026 May;40(5):2895-2914
Phytotherapy research : PTR 2026 May;40(5):2895-2914
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
Yuan Q, Zhao Y, Zhou F, Zhang Y, Jia X, Yao J, Lv M, Wang J, Lv L
International journal of biological macromolecules 2026 May;361:151988
International journal of biological macromolecules 2026 May;361:151988
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Li S, Chen L, Fang Z, Shen W, Cai J, Dong B, Lin T, Zhang R, Jin L, Liu C, Wu F, Wu Q, Chen D
Free radical biology & medicine 2026 May;248:401-412
Free radical biology & medicine 2026 May;248:401-412
Multi-omics reveals that 4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota.
Zhang T, Zou R, Chen Z, Li Y, Sun X, Sun X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Yitangkang decoction in the treatment of glomerular filtration barrier damage through AMPKα1/ZDHHC8/SLC7A11/GPX4 and TGF-β/Smad signaling pathways: A multi-omics analysis.
Yu J, Zhang H, Wu Y, Di Z, Shi Y, Fan X, Dong B, Dai J, Wang Z, Chen Y, Liu W, Zhang W
Journal of ethnopharmacology 2026 May 23;363:121410
Journal of ethnopharmacology 2026 May 23;363:121410
NUP62 promotes breast cancer progression and inhibits ferroptosis by stabilizing NRF2 in a KEAP1-dependent way.
Qiu Z, Lin Y, Chen S, Cao W, Yang J, Li R, Chen Y, Yao X, Fu S, Jin N
iScience 2026 May 15;29(5):115484
iScience 2026 May 15;29(5):115484
Multifunctionally Modified Low Molecular Weight PEI for Efficient Gene Delivery and Ferroptosis-Induced Antitumor Activity.
Lei Y, Sun S, Wang R, Zhang J
Biomacromolecules 2026 May 11;27(5):3292-3302
Biomacromolecules 2026 May 11;27(5):3292-3302
Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis.
Zhu Y, Zhao W, Li W, Wang J, Chen H, Wang Z, Wang X, Chen X
Journal of advanced research 2026 Mar;81:673-687
Journal of advanced research 2026 Mar;81:673-687
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Yang F, Liu D, Hu L, Tan H, Wei Y, Yang R, Huang B, Zou Q, Wu Q, He Y, Mai H, Lan X, Yan Y, Huang Z, Huang X, Fu Z, Deng Z, Huang Q, Yao S, Liang Y
Molecular and cellular endocrinology 2026 Mar;613:112721
Molecular and cellular endocrinology 2026 Mar;613:112721
Concurrent Ferroptosis and Apoptosis in Resveratrol-Treated Glioblastoma Cells: Relevance With NRF2 Downregulation and Oxidative Stress.
Farman A, Zheng X, Wu ML, Hong L, Qian W, Liu J
Cell biology international 2026 Mar;50(3):e70153
Cell biology international 2026 Mar;50(3):e70153
PDK4-driven lactate accumulation facilitates LPCAT2 lactylation to exacerbate sepsis-induced acute lung injury.
Deng Y, Qiu Y, Li X, Gong T, Guo J, Liang H, Yuan Z, Hei Z, Zhang X, Liu Y
Cell death and differentiation 2026 Mar;33(3):557-573
Cell death and differentiation 2026 Mar;33(3):557-573
Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway
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Li P, Wan X, Li W, Cheng D, Yang Y, Wang Y, Zhu R, Chen Y, Liu H, Zhang Z
Molecular medicine reports 2026 Mar;33(3)
Molecular medicine reports 2026 Mar;33(3)
Acceleration of Lactate Uptake and Utilization Contributes to Neuroprotective Action of FGF21 Involved in Naturally Aging Mice.
Ji K, Wei H, Wang R, Wu Y, Li C, Gao H, Zhao L
Aging cell 2026 Mar;25(3):e70423
Aging cell 2026 Mar;25(3):e70423
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
Zuo T, Shi C, Li J, Li D, Luo X, Xu M, Su M, Lu H, Zhang Y, Hu X, Zhou Q, Shubhra QTH, He X, Cai X
Acta biomaterialia 2026 Mar;212:593-612
Acta biomaterialia 2026 Mar;212:593-612
Apatinib and silver nanoparticles synergize against gastric cancer through the PI3K/Akt signaling pathway-mediated ferroptosis.
Lin Z, Deng Z, Liang J, Chen B, Huang Y, Liu B, Zhao Y
Journal of pharmaceutical analysis 2026 Mar;16(3):101400
Journal of pharmaceutical analysis 2026 Mar;16(3):101400
M6A reader IGF2BP3 stabili1zes SLC7A11 to antagonize ferroptosis and promote gastric tumorigenesis.
Yang Y, Ye H, Qin S, Lin M, Liu Y, Li X
Cellular signalling 2026 Mar;139:112295
Cellular signalling 2026 Mar;139:112295
USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer.
Chen W, Wang L, Fan H, Li L, Zhang L, Li R, Liu F, Wen F, Ye Y, Huang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e16588
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e16588
Trolline attenuates diabetic vascular injury by regulating SLC7A11-mediated ferroptosis and mitochondrial dysfunction.
Liu W, Lu C, Yang B, Liu Y, Yan J, Song T, Wang X
Gene 2026 Mar 5;981:149968
Gene 2026 Mar 5;981:149968
Curcumin protects against difenoconazole-induced kidney injury in carp by inhibiting ferroptosis through the Nrf2/GPX4 axis.
Zhang S, Li X, Gao Y, Dong Q, Jin X, Shi P, Dong J
Fish physiology and biochemistry 2026 Mar 5;52(2)
Fish physiology and biochemistry 2026 Mar 5;52(2)
NOX1/4 drives hepatic iron and lipid dysregulation, redox imbalance, and inflammation in ethanol-fed mice.
Yu L, He T, Zhang P, Zhao X, Xun L, Li R, Wan P
Scientific reports 2026 Mar 5;16(1)
Scientific reports 2026 Mar 5;16(1)
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
Duan Z, Zhuo B, Ma D, Hua Z, Han X, Cai L, Yang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
The effect and mechanism of albiflorin in alleviating hepatic fibrosis by mediating hepatocyte ferroptosis via the SLC7A11/GPX4 signaling pathway.
Liu Y, Li S, Zhao X, Tian J, Xiao Z, Ma S
Journal of ethnopharmacology 2026 Mar 25;359:121080
Journal of ethnopharmacology 2026 Mar 25;359:121080
Disulfidptosis induced by intermittent fasting and metformin enhances the efficacy of anti-PD-1 therapy in renal cancer.
Wang H, Qi Y, Zhou Y, Xia W, Dong Y, Ren L, Xia Z, Li Q, Chen Z, Yang Z, Wang Y, Zhang C
Cell communication and signaling : CCS 2026 Mar 24;24(1)
Cell communication and signaling : CCS 2026 Mar 24;24(1)
FAK/SRC-JNK axis promotes ferroptosis via upregulating ACSL4 expression.
Qin J, Ma S, Wang J, Huang S, Luan J, He J, Hou G, Sun N, Zhang W, Gao M
Cell death & disease 2026 Mar 20;17(1)
Cell death & disease 2026 Mar 20;17(1)
Study on the effects and mechanisms of M2 macrophages on PYCR1-promoted biological behavior of hepatocellular carcinoma cells.
Jin X, Hou Y, Guo J, Zhang J, Wu W
Scientific reports 2026 Mar 16;16(1)
Scientific reports 2026 Mar 16;16(1)
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Chen SX, Qi X, Zheng XT, Bi ZM, Zhang Y, Wang YM
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
AMBRA1 activation alleviates zearalenone-induced swine testicular cell ferroptosis by facilitating mitophagy.
Hu Z, Yang S, Zhang X, Lou M, Yu Q, Cheng Y, Chang Y, Jiang F, Chen M, Wang J, Song Y, Zheng J, Mao X, Wang Y, Li J, Zhao Y
Journal of animal science and biotechnology 2026 Mar 14;17(1)
Journal of animal science and biotechnology 2026 Mar 14;17(1)
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Xu Y, Zhang Y, Sun Z, Gong J, Shen Q, Meng H, Liu X, Chen J, Hao Y, Xu Z, Ma K, Ma L, Guo K, Pan X, Fu X, Zhang C
Materials today. Bio 2026 Jun;38:103117
Materials today. Bio 2026 Jun;38:103117
Protean bio-heterojunction nanoparticle coating for dynamically modulating diabetic microenvironment.
Pan L, Zheng A, Huang N, Zhang S, Peng L, Zheng F, Cao L, Wang X, Jiang X
Biomaterials 2026 Jun;329:123912
Biomaterials 2026 Jun;329:123912
Bufotenidine attenuates astrocyte ferroptosis in depressive-like behaviors through targeting GluA1 to reduce neuronal lipid synthesis.
Wu W, Chen Z, Xu Y, Xie X, Tan A, Hu M, Xu D, Lv X, Chen W, Zhou J, Zhu Y, Ma H
Free radical biology & medicine 2026 Jun;249:589-602
Free radical biology & medicine 2026 Jun;249:589-602
Cancer cell membrane and iRGD peptide co-modified cantharidin liposomes for targeted therapy and immunotherapy of triple-negative breast cancer.
Guo Q, Wang S, Zhong Z, Zhou L, Xia X
Free radical biology & medicine 2026 Jun;249:273-291
Free radical biology & medicine 2026 Jun;249:273-291
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Cheng Y, Shi YZ, Zheng JY, Liu YB, Chen YT, Bao JX, He XY, Chen JQ, Li Q, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Role of PTP1B in coordinating synaptic plasticity and ferroptosis: A mechanism underlying the antidepressant effect of spinosin from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou.
Wang Y, Zhang Y, Wang J, Wu X, Li Y, Sun W, Song L, Gong M, He Q, Qin L, Wang Q, Ji L, Zhang T
Journal of ethnopharmacology 2026 Jun 12;364:121428
Journal of ethnopharmacology 2026 Jun 12;364:121428
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Wu W, Cheng Z, Shi P, Gao H, Chen X, Wu W, Yu Z, Yang C, Zhang Y
Bioactive materials 2026 Jul;61:555-576
Bioactive materials 2026 Jul;61:555-576
CDDO-Me alleviates doxorubicin/lapatinib-induced cardiotoxicity by activating the NRF2/GPX4 axis to inhibit oxidative stress and ferroptosis.
Chen X, Chen B, Hu Q, Suo L, Yin M, Huang G, Huang Z, Yin Y, Zhou W
Free radical biology & medicine 2026 Jul;250:468-482
Free radical biology & medicine 2026 Jul;250:468-482
Pyrvinium pamoate inhibits the survival of intracellular Mycobacterium tuberculosis through suppression of macrophage ferroptosis.
Guan Q, Zhou Y, Han JL, Guo F, Li Z, Zhou Y, Zhang XL
Bioorganic chemistry 2026 Jul 5;175:109753
Bioorganic chemistry 2026 Jul 5;175:109753
Design and synthesis of dual mitochondria-targeted biguanide derivatives as potential anticancer agents.
Ning Y, Yang X, Chen L, Yi J, Li J, Lin Y, Mu L, Xu C
Bioorganic chemistry 2026 Jul 15;176:109847
Bioorganic chemistry 2026 Jul 15;176:109847
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Li R, Zhu Y, Wei H, Yu M, Xu Y
International immunopharmacology 2026 Jul 1;180:116688
International immunopharmacology 2026 Jul 1;180:116688
Identifying cathepsin B as a key regulator of programmed cell death in acute pancreatitis.
Xie X, Jia Y, Wang Z, Zhang H, Lu J, Cao F, Li F
International immunopharmacology 2026 Jul 1;180:116680
International immunopharmacology 2026 Jul 1;180:116680
SS-31 improves post-cardiac arrest brain injury by inhibiting microglial ferroptosis and polarization.
Jiang T, Zhang H, Sun Y, Ji X, Xue L, Pan C, Guo Y, Xu F
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2026 Jan;23(1):e00772
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Dong R, Wang G, Shi Y, Gao J, Hu W, Zhang T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Muskardia inhibits proliferation and migration of human coronary artery smooth muscle cells by regulating SLC7A11 mRNA stability via the hsa_circTEX10-PCBP2 Axis.
Li C, Duan M, Chen Z, He S, Chi B, Zhang X, Ren M, Bie H, Jia Q, An F, Wang G, Jia E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157709
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157709
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Li Z, Sun S, Zhao Z, Guo Y, He Q, Yang M, Zheng J, Li J, Xue W, Ding C
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells.
Yang F, Liang P, Guo H, Yan W, Wang G, Tang X, Liang Z
International journal of immunopathology and pharmacology 2026 Jan-Dec;40:3946320261427239
International journal of immunopathology and pharmacology 2026 Jan-Dec;40:3946320261427239
Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation.
Drekolia MK, Mettner J, Wang D, Delgado Lagos F, Koch C, Hecker D, Eresch J, Mao Y, Bähr M, Weichenhan D, Cordero J, Wittig J, Zhang B, Cui H, Li X, Oo JA, Weigert A, Siragusa M, Klatt S, Fleming I, Günther S, Looso M, Brandes RP, Langer HF, Papapetropoulos A, Singhal M, Schulz MH, Plass C, Heineke J, Dobreva G, Hu J, Bibli SI
Cell metabolism 2026 Jan 6;38(1):115-134.e20
Cell metabolism 2026 Jan 6;38(1):115-134.e20
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Yu C, Zhang T, Yuan J, Su Y, Zhang H, Xu L, Li X, Cui J, Xu R, Zhou Y, Huang H, Zhou X, Zhou Y, Zhang E
Cancer cell international 2026 Jan 6;26(1):64
Cancer cell international 2026 Jan 6;26(1):64
Dictamnine inhibited keratinocyte hyperproliferation and alleviated psoriasis-like dermatitis via blocking HIF1A-mediated ferroptotic pathway.
Wang W, Zhang J, Jiang SL, Rao ZM, Liu H, Wang L, Cai CL, Xu XC, Yu CH, Wang W
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120607
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120607
Rottlerin triggers dual degradation of SLC7A11 and GPX4 to drive ferroptosis and chemosensitization in hepatocellular carcinoma.
Luo H, Jin X, Gao C, Deng Q, Han L, Hu F, Tong R, Li D, Yang H, Bian X
Cell death discovery 2026 Jan 30;12(1):89
Cell death discovery 2026 Jan 30;12(1):89
Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway.
Zhang H, Chang A, Xu X, Peng H, Zhang K, Yang J, Li W, Wang X, Wang W, Yin X, Qu C, Dong X, Ni J
Current issues in molecular biology 2026 Jan 27;48(2)
Current issues in molecular biology 2026 Jan 27;48(2)
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Li Y, Zhang B, Zhang Z, Yan W, Wang H, Xu X, Lv A, Liao Z, Guo L
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Ferroptosis-related gene signature predicts prognosis and immunotherapy response in hepatocellular carcinoma: A multi-cohort retrospective study.
Li L, Pang J, Chen J, Pan Y, Liang L, Bai X, He Y, Yang H
Medicine 2026 Jan 23;105(4):e47262
Medicine 2026 Jan 23;105(4):e47262
Integrating bioinformatic analyses and experimental validation of disulfidptosis-related genes and TMX4 in melanoma progression.
Yi Y, Tao R, Shi Z, Chen L, Zhu Z, Wu M
Cancer cell international 2026 Jan 20;26(1):86
Cancer cell international 2026 Jan 20;26(1):86
Moscatilin alleviates severe acute pancreatitis by activating the NRF2/HO-1 pathway to inhibit ferroptosis.
Niu L, Yang Z, Zeng Y, Huang Z, Yang T, Liu S, Zhong H, Ye M, Lei S, Gao L, Tan P, Fu W
International immunopharmacology 2026 Jan 15;169:115972
International immunopharmacology 2026 Jan 15;169:115972
SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer.
Zhong H, Chen R, Chen T, Lin M, Wen S, Zhang M, Liu D, Yu J, Chen J, Yi B, Liang R, Jiang W, Li Z
Apoptosis : an international journal on programmed cell death 2026 Jan 10;31(1):30
Apoptosis : an international journal on programmed cell death 2026 Jan 10;31(1):30
Modulation of Macrophage ferroptosis under the guide of infrared thermography promotes the healing of pressure injuries.
Jiang X, Zhang X, Deng H, Lin L, Wang Y, Wang Y, Huang J, Yang N, Xu S, Wang J, Shi K, Tao K, Chen Z, Cai F, Zhou K, Xiao J
Journal of advanced research 2026 Feb;80:265-285
Journal of advanced research 2026 Feb;80:265-285
NSUN2 Knockdown Promotes the Ferroptosis of Colorectal Cancer Cells Via m5C Modification of SLC7A11 mRNA.
Tong R, Li Y, Wang J, Liu C, Liu Y, Li R, Wang X
Biochemical genetics 2026 Feb;64(1):524-537
Biochemical genetics 2026 Feb;64(1):524-537
Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway.
Jinke H, Jiaqi Z, Zhihong L, Jing MA, Fengyun W, Xudong T
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):34-38
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):34-38
Integrating TWAS, chemical-genomic networks, and experimental models: melatonin as a ferroptosis inhibitor in osteoarthritis therapy.
Feng R, Aihaiti Y, Yu H, Xu K, Lu C, Xu P
Clinical rheumatology 2026 Feb;45(2):1559-1572
Clinical rheumatology 2026 Feb;45(2):1559-1572
Protective Effects of Liriodendrin Against Oxidative Stress and Ferroptosis in a Mouse Model of Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.
Lin FC, Wu SW, Chen SP, Su CH, Tsai SC, Kuan YH
Environmental toxicology 2026 Feb;41(2):131-140
Environmental toxicology 2026 Feb;41(2):131-140
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Dou T, Zhu X, Li H, Wang R, He J, Geng H, Zhang W, Yu Q, Zhao H, Yang H
Genes and immunity 2026 Feb;27(1):91-105
Genes and immunity 2026 Feb;27(1):91-105
Smart responsive injectable hydrogel loaded with icariin inhibits ferroptosis and promotes nucleus pulposus repair in intervertebral disc degeneration.
Lin Z, Mai L, Luo H, Wang Z, Lin Y, Wang H, Chen S, Su G, Hu X, Chen B, Cao X
Biomaterials advances 2026 Feb;179:214513
Biomaterials advances 2026 Feb;179:214513
A Functional Nanocomposite Tri-Activates Cuproptosis, Ferroptosis, and Mitophagy Death Pathway to Oppose Malignancies.
Deng K, Gao W, Wen Y, Huang J, Li X, Yang X, Wu M
Advanced healthcare materials 2026 Feb;15(6):e03530
Advanced healthcare materials 2026 Feb;15(6):e03530
Melatonin counteracts Iodoacetic acid induced ferroptosis by regulating Nrf2 in porcine oocytes.
Lu QY, Zhan CL, Lee SH, Li XH, Kim JD, Lee GH, Sim JM, Song HJ, Jin YY, Cui XS
Cellular signalling 2026 Feb;138:112257
Cellular signalling 2026 Feb;138:112257
Curcumin pretreatment enhances the capacity of BMSC exosomes to attenuate renal ischemia-reperfusion injury by ferroptosis suppression via miR-16-5p/Smad3/Mb axis.
Chen B, Chen J, Shen Z, Liu S, Mei Y, Cai H, Li K, Peng Z, Zhang L, Wang W, Lu S
Stem cell research & therapy 2026 Feb 9;17(1)
Stem cell research & therapy 2026 Feb 9;17(1)
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Yi D, Wu Z, Li X, Shao B, Xiao Y, Li T, Zhang X, Zhu J, Yang T, Deng Y, Huang T, Qiu T, Bai J, Shi X, Wu C, Wu Z, Sun X, Wang N
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
A novel mechanism of chlorogenic acid against type 2 diabetes-induced diabetic retinopathy: suppressing ferroptosis via NRF2/xCT/GPX4 and STAT3 signaling.
Zheng J, Wang X, Guo Y, Feng L
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb 23;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Feb 23;
Targeting mitochondrial phosphatase PGAM5 alleviates ferroptosis and acute pancreatitis by upregulating NRF2-mediated FSP1 expression.
Ma S, Qin J, Luan J, Hou G, He J, Gao M
Cell death & disease 2026 Feb 21;17(1)
Cell death & disease 2026 Feb 21;17(1)
Saposhnikovia divaricata Inhibits Inflammation, Oxidative Stress, and Ferroptosis to Alleviate DSS-Induced Ulcerative Colitis.
Liu L, Dou Q, Zhao X, Liang Y, Tian Z, Su D, Zhou L, Hu X
Antioxidants (Basel, Switzerland) 2026 Feb 18;15(2)
Antioxidants (Basel, Switzerland) 2026 Feb 18;15(2)
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
Nie R, Zhou H, Chen L, Quan H, Zhang Y, Lin Z
Cell death discovery 2026 Feb 18;12(1)
Cell death discovery 2026 Feb 18;12(1)
CircRNA-TMEM71 Inhibits Human Aortic Smooth Muscle Cell Ferroptosis and Prevents Aortic Dissection Formation Through IGF2BP3-Mediated Stability of FSP1.
Zhu L, He C, Shi H, Shao G, Sun L
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
Journal of the American Heart Association 2026 Feb 17;15(4):e043108
Integrated multi-omics analysis reveals GPD1L-mediated dysregulation of glycerophospholipid metabolism facilitates the progression of lung adenocarcinoma.
Sun Y, Yan Y, Zhou Y, Chen Y, Liu C, Bao Y, Zhang Y, Han H, Chen H
Respiratory research 2026 Feb 14;27(1):86
Respiratory research 2026 Feb 14;27(1):86
Supplemental exposure to polystyrene nanoplastics synergistically amplifies calcium oxalate crystal-induced injury to renal tubular epithelium, accelerating the formation of calcium oxalate kidney stones.
Su X, Yang Y, Xiang H, Dong C, Shi M, Wang Y, Zhou Q, Song Q, He Z, Jiang Q, Chen B, Wang Y, Xiong Y, Yang S
Particle and fibre toxicology 2026 Feb 12;23(1)
Particle and fibre toxicology 2026 Feb 12;23(1)
TFEB-nuclear translocation promotes BNIP3-mediated mitophagy and alleviates oxidative stress and ferroptosis in acute pancreatitis.
Zhang H, Jia Y, Wang Z, Li J, Xie X, Ding Y, Cao F, Li F
Free radical biology & medicine 2026 Feb 1;243:398-413
Free radical biology & medicine 2026 Feb 1;243:398-413
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275
Free radical biology & medicine 2026 Feb 1;243:260-275
Bromodomain-containing protein 4 knockdown promotes neuronal ferroptosis in a mouse model of subarachnoid hemorrhage.
Lu P, Zhang F, Yang L, He Y, Kong X, Guo K, Xie Y, Xie H, Xie B, Jiang Y, Peng J
Neural regeneration research 2026 Feb 1;21(2):715-729
Neural regeneration research 2026 Feb 1;21(2):715-729
Nrf2 de-SUMOylation alleviates myocardial ischemia-reperfusion injury (MIRI) by attenuating myocardial ferroptosis in mice.
Shi Q, Yao W, Zhang W, Xu J, Wang X, Wei X, Hu S, Fan Q, Yang H, Wu X, Cai R
Redox report : communications in free radical research 2026 Dec;31(1):2624946
Redox report : communications in free radical research 2026 Dec;31(1):2624946
Xin Jia congrong tusizi decoction reverses ferroptosis in granulosa cells to rescue ovarian function decline via p53/Nrf2/SLC7A11/GPX4 signaling pathway.
Liu M, Sun Y, Liu X, Wei S, Yang J, Wang Y, Wu K, Wu Y
Journal of ethnopharmacology 2026 Aug 10;367:121659
Journal of ethnopharmacology 2026 Aug 10;367:121659
Ageing promotes metastasis via activation of the integrated stress response.
Patel AAH, Dzanan JJ, Ali KX, Eklund EA, Alvarez SW, Raj D, Dankis M, Altinönder I, Schwarz M, Le Gal K, Bedel E, El Zowalaty AE, Jonasson E, Albatrok H, Gul N, Bossowski JP, Pillai R, Micke P, Botling J, Akyürek LM, Angeletti D, Sayin SI, Härtlova A, Papagiannakopoulos T, Olofsson Bagge R, Ståhlberg A, Hallqvist A, Wiel C, Sayin VI
Nature 2026 Apr;652(8112):1339-1348
Nature 2026 Apr;652(8112):1339-1348
Injectable Zn(2+)-Driven carrier-free hydrogel via self-assembly of natural small molecules for liver fibrosis therapy through concurrent autophagy activation and ferroptosis inhibition.
Zhu C, Jia S, Wang J, Gao F, Lin Y, Nie A, Guo Z, Zhou Z, Xu B, Lei H
Materials today. Bio 2026 Apr;37:102828
Materials today. Bio 2026 Apr;37:102828
Puerarin promotes nerve regeneration and functional recovery after peripheral nerve injury by inhibiting ACSL4-dependent ferroptosis.
Sun T, Huang L, Zhao Y, Sun Q, Luo X, Wu Z, Sun J, Li M, Huo Q, Wang H
International journal of biological macromolecules 2026 Apr;357:151404
International journal of biological macromolecules 2026 Apr;357:151404
Di-(2-Ethylhexyl) phthalate causes testicular ferroptosis though deficiency of androgen receptor and disruption of mitochondrial quality control.
Tian Q, Yan X, Xu J, Ma J, Sun X, Li J, Wang N, Yao X, Qiu T, Zhang C, Deng H, Yang G
Free radical biology & medicine 2026 Apr;247:348-360
Free radical biology & medicine 2026 Apr;247:348-360
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
Ren J, Wu S, Su T, Li H, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
Apigenin-5-O-glucoside alleviates hepatic fibrosis through NOX4-mediated ferroptosis in zebrafish.
Li M, Deng K, Cheng J, Shi H, Li Y, Wang Y, Wen J, Lv Z, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157956
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157956
Remimazolam Ameliorates Autistic-Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD.
Zhang Y, Lin J, Tong C, Fu X, Shan M, Huang Y, Zhang K, Zheng J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e08520
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(20):e08520
Inhibition of Calcium-Dependent Lipid Droplets Relocation of ACSL4-PKCβ-ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis.
Hou G, Luan J, Xu X, Qin J, Ma S, He J, Sun N, Zhang W, Gao M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e15768
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(19):e15768
Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease.
Tang Y, Wang S, Wang Y, Zhang T, Liu Y, Di Y
Histochemistry and cell biology 2026 Apr 5;164(1)
Histochemistry and cell biology 2026 Apr 5;164(1)
Stabilizing MARCH7 as a ferro-guardian against ferroptosis.
Huang W, Wang R, Yang X, Yang S, Yang X, He G, Dai S, Li C, Gao L, Zhang T, Zhang P, Chen R, Zheng K, Wu J, Min J, Ba Q, Wang F, Zhang Q
Cell 2026 Apr 27;
Cell 2026 Apr 27;
Downregulation of SELENOS Suppresses the Progression of Renal Cell Carcinoma by Activating Ferroptosis.
Li Q, Wu Y, Xu Y, Shi H, Xu J, Xu S
Biological trace element research 2026 Apr 22;
Biological trace element research 2026 Apr 22;
Aberrant expression of TRIM26 suppresses ferroptosis through regulating GPX4 protein stability in colorectal cancer.
Wu G, Zheng K, Xu S, Wang J, Xu J
Molecular biology reports 2026 Apr 16;53(1)
Molecular biology reports 2026 Apr 16;53(1)
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
Yu L, Zhai Z, Wang Y, Wang L, Li Q, Guo Y, Liang Y, Tang L
International immunopharmacology 2026 Apr 15;175:116448
International immunopharmacology 2026 Apr 15;175:116448
Peroxisome-derived and liver-specific hydroxyacid oxidase 1-mediated hydrogen peroxide promotes ferroptosis by augmenting peroxisomal ROS.
Peng X, Zhou Y, Chen J, Wang Z, Peng X, Wang H, Shu L, Liu N, Long Y, Linghu L, Zhang Z, Peng Y, Zhao Y, Xiao D, Shi Y, Liu S, Tao Y
Journal of advanced research 2026 Apr 15;
Journal of advanced research 2026 Apr 15;
Saikosaponin D Alleviates Liver Ischemia-Reperfusion Injury by Inhibiting Mitophagy-Associated Ferroptosis via the STAT3/PINK1 Pathway.
Liu X, Xu Y, Yu X, Feng X, Han Y, Cai H, Du J, Chen L
Phytotherapy research : PTR 2026 Apr 12;
Phytotherapy research : PTR 2026 Apr 12;
EGF-Upregulated lncRNA ESSENCE Promotes Colorectal Cancer Growth through Stabilizing CAD and Ferroptosis Defense.
Xie X, Zhang B, Peng J, Ma N, Pan Q, Wei Y, Jin H, Yu F, Huang X, Zhang P, Wang J, Zheng J, Ying X, Liu RY, Yu H, Lee MH, Meng X
Research (Washington, D.C.) 2025;8:0649
Research (Washington, D.C.) 2025;8:0649
CircRNA circ_0015278 induces ferroptosis in lung adenocarcinoma through the miR-1228/P53 axis.
Xia L, Li G, Zhou Q, Feng YU, Ma H
Oncology research 2025;33(2):465-475
Oncology research 2025;33(2):465-475
TMEM105 modulates disulfidptosis and tumor growth in pancreatic cancer via the β-catenin-c-MYC-GLUT1 axis.
Yin Y, Sun Y, Yao H, Yu F, Jia Q, Hu C, Zhu Y, Duan Z, Liu D, Sun Y, Huo Y, Yang M, Liu W
International journal of biological sciences 2025;21(5):1932-1948
International journal of biological sciences 2025;21(5):1932-1948
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274
International journal of biological sciences 2025;21(3):1259-1274
Ferroptosis-Resistant Adipocytes Drive Keloid Pathogenesis via GPX4-Mediated Adipocyte-Mesenchymal Transition and Iron-Cystine Metabolic Communication.
Shi X, Xia X, Xiao Y, Shu H, Xu Z, Liu M, Shi C, Zhang Y, Wei Y, Gong Y, Wang W, Chen Y, Liu J, Huang J, Shi M, Wang J, Wu W
International journal of biological sciences 2025;21(11):5097-5115
International journal of biological sciences 2025;21(11):5097-5115
Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells.
Huang M, Li D, Xia Z, Liao S, Si W, Yuan C, Liao Y, Wu W, Jiang M, Yu X, Quan Y
PloS one 2025;20(5):e0322746
PloS one 2025;20(5):e0322746
CMSP exerts anti-tumor effects on small cell lung cancer cells by inducing mitochondrial dysfunction and ferroptosis.
Yan X, Niu Y, Wang Y, Wei S, Han L, Guo Z, Zhao L, Gao F
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Open medicine (Warsaw, Poland) 2025;20(1):20241100
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Wang W, Li Z, Lyu C, Wang T, Han C, Cui S, Wang J, Xu R
International journal of nanomedicine 2025;20:4035-4050
International journal of nanomedicine 2025;20:4035-4050
Sakuranetin Prevents Acetaminophen-Induced Liver Injury via Nrf2-Induced Inhibition of Hepatocyte Ferroptosis.
Long Z, Yu X, Li S, Cheng N, Huo C, Zhang X, Wang S
Drug design, development and therapy 2025;19:159-171
Drug design, development and therapy 2025;19:159-171
Ghrelin alleviates high glucose-induced retinal microvascular endothelial cell injury by activating Nrf2/HO-1 pathway to inhibit ferroptosis.
Wang FF, Li R, Liao D, Liu CQ, Yang XL
International journal of ophthalmology 2025;18(6):978-985
International journal of ophthalmology 2025;18(6):978-985
Astragaloside IV Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis via the p53/SLC7A11/GPX4 Axis.
Tang Z, Cheng L, Li M, Chen J, Huang C
Journal of inflammation research 2025;18:16169-16186
Journal of inflammation research 2025;18:16169-16186
Carnosic acid attenuates diabetic retinopathy via the SIRT1 signaling pathway: neuroprotection and endothelial cell preservation.
Mai H, Liu C, Fu B, Ji X, Chen M, Zhang Y, Lin Y, Chen J, Song Y, Gu S
American journal of translational research 2025;17(3):2293-2310
American journal of translational research 2025;17(3):2293-2310
Clara cell secretory protein 16 protects against PM2.5-induced ferroptosis in mouse lung epithelial cells in a concentration-dependent manner.
Wang A, Lin J, Yang S
American journal of translational research 2025;17(10):7915-7926
American journal of translational research 2025;17(10):7915-7926
Ferroptosis-related genes as prognostic markers for survival and immunotherapy in triple-negative breast cancer: analysis of public databases and a single institution.
Xie Y, Tao Z, Wang B, Zhao Y, Chen X, Li B, Wang J, Chen G, Hu X
Therapeutic advances in medical oncology 2025;17:17588359251322291
Therapeutic advances in medical oncology 2025;17:17588359251322291
Resveratrol Induces Oxidative Stress and Downregulates GPX4 and xCT to Activate the Ferroptosis Pathway for Anti-Bladder Cancer Organoids.
Chen X, Lu JL, Li H, Liu GY, Li TT, Xiao KH, Ye HS, Li S, Chen X, Liu J
Journal of Cancer 2025;16(8):2613-2625
Journal of Cancer 2025;16(8):2613-2625
Integrated network pharmacology and experimental verification to reveal the mechanisms of curcumin in the treatment of colorectal cancer.
Yuan Z, Hu J, Cai C, Liu F, Chen H, Zeng B
Frontiers in pharmacology 2025;16:1703562
Frontiers in pharmacology 2025;16:1703562
SDCBP2 promotes tumor progression and is a novel ferroptosis-related prognostic biomarker in lung adenocarcinoma.
Sun S, Gu Z, Yuan S, Zhang K, Liu W, Wei Z, Fan W, Wang Z, Zhao T, Tang M, Gao X, Zhang G, Li X, Pan X
Frontiers in immunology 2025;16:1692308
Frontiers in immunology 2025;16:1692308
Vitamin D ameliorates prediabetic cardiac injure via modulation of the ErbB4/ferroptosis signaling axis.
Miao Y, Zhang Y, Zhang L, Chen H, Tang L, Li W, Gu C, Lang L, Li X, Song H
Frontiers in immunology 2025;16:1626295
Frontiers in immunology 2025;16:1626295
Identification of ferroptosis-genes associated with pediatric inflammatory bowel disease bioinformatics and machine learning approaches.
Xu Z, Yang M, Ou C, Mao L, Liu Z
Frontiers in immunology 2025;16:1619944
Frontiers in immunology 2025;16:1619944
The pivotal regulatory role of the FEV-SLC7A11 axis in ferroptosis elucidates the anti-aging mechanism of β-sitosterol in a cross-species study.
Fang Z, Xie L, Wang J, Li J, Pan Y, Chen L, Cao S, Zhou Q, Li S, Zhang C, Li L
Frontiers in pharmacology 2025;16:1600489
Frontiers in pharmacology 2025;16:1600489
FGA modulates immune infiltration and tumor progression via SLC7A11/xCT-mediated disulfidptosis in the tumor microenvironment of lung adenocarcinoma.
Li G, Li Q, Yang S, Guo D, Tao Y, Jia Y
Frontiers in immunology 2025;16:1595900
Frontiers in immunology 2025;16:1595900
Synergistic effect of regorafenib with aminoglycosides in ferroptosis-mediated liver injury.
Raja Dahar M, Zhou S, Hu H, Lei J, Zeng K, Yu L
Frontiers in pharmacology 2025;16:1586578
Frontiers in pharmacology 2025;16:1586578
Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in intestinal cells.
Zhao X, Yan L, Tian L, Zhang X, Liu R, Li Z
Frontiers in pharmacology 2025;16:1581085
Frontiers in pharmacology 2025;16:1581085
Hydrogen sulfide and ferroptosis inhibition underlies the dietary restriction-induced protection against cyclophosphamide cystitis.
Mao Z, Chen P, Ji Q, Zhao X, Zhong K, Zeng X
Frontiers in pharmacology 2025;16:1562852
Frontiers in pharmacology 2025;16:1562852
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Wang H, Chen B, Xiao P, Han D, Gao B, Yan Y, Zhao R, Pan T, Zhang J, Zhou M, Lv L, Gao H
Frontiers in microbiology 2025;16:1542801
Frontiers in microbiology 2025;16:1542801
Metformin attenuates diabetic osteoporosis by suppressing ferroptosis via the AMPK/Nrf2 pathway.
Liu Y, Fu Z, Wang X, Yang Q, Liu S, Zhu D
Frontiers in pharmacology 2025;16:1527316
Frontiers in pharmacology 2025;16:1527316
Bioactive natural alkaloid 6-Methoxydihydrosanguinarine exerts anti-tumor effects in hepatocellular carcinoma cells via ferroptosis.
Han L, Gao C, Jin X, Li Y, Chen L, Li D, Deng Q, Bian X
Frontiers in pharmacology 2025;16:1500461
Frontiers in pharmacology 2025;16:1500461
STOML2 inhibits sorafenib-induced ferroptosis in hepatocellular carcinoma via p-AKT signaling pathway.
Yin R, Tao Y, Han J, Zhang J, Yu K, Zheng Y, Li X, Huang C
American journal of cancer research 2025;15(4):1614-1628
American journal of cancer research 2025;15(4):1614-1628
The contrasting regulatory effects of valproic acid on ferroptosis and disulfidptosis in hepatocellular carcinoma.
Liu R, Li X, Xu J, Yan L, Hu K, Shi M, Zhang Y, Zhao Y, Fan Y, Wang G, Guo Y, Feng Y, Liu P
Theranostics 2025;15(17):9091-9113
Theranostics 2025;15(17):9091-9113
Injectable SF-platform orchestrates GPX4-targeted ferroptosis-autophagy-immunogenic circuit for overcoming oxidative resistance in triple-negative breast cancer.
Yuan H, Li X, Yu M, Cao Y, Wu L, Shi S, Yang Y, Yu K, Liang B
Theranostics 2025;15(17):8757-8778
Theranostics 2025;15(17):8757-8778
Asaraldehyde suppresses non-small cell lung cancer progression via ferroptosis induction and inhibition of PI3K-AKT signaling.
Yin H, Hu Z, You ZR, Xiao CX, Li XX, Liu ZF, Xu GQ
American journal of cancer research 2025;15(10):4276-4290
American journal of cancer research 2025;15(10):4276-4290
Ginsenoside Rh2 repressed the progression of prostate cancer through the mitochondrial damage induced by mitophagy and ferroptosis.
He Z, Shi J, Zhu B, Tian Z, Zhang Z, Zhang C
Frontiers in oncology 2025;15:1633891
Frontiers in oncology 2025;15:1633891
Bioinformatics and experimental unveiling of TIMP1 as a novel therapeutic target in colorectal cancer ferroptosis.
Tang C, Li Z, Song T, Lu L, Chen B, Zhang T, Zhang Y, Yang J, Lao J, Chen H
Frontiers in oncology 2025;15:1593107
Frontiers in oncology 2025;15:1593107
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer.
Zheng X, Li W, Li X, Yao Q, Zheng L, Fan R, Bie P
Frontiers in oncology 2025;15:1585236
Frontiers in oncology 2025;15:1585236
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Song Y, Hai E, He L, Zhang N, Zhang N, Wang J, Sun Y, Zeng D, Zhang J
Frontiers in cell and developmental biology 2025;13:1610621
Frontiers in cell and developmental biology 2025;13:1610621
Perillaldehyde synergizes with ferroptosis inducers to promote ferroptotic cell death in gastric cancer.
Wang R, Cui JF, Lv J, Song JL, Lu YY, Huang XJ, Lin ZK, Zhang SY, Wang SS, Qiu WS
Frontiers in cell and developmental biology 2025;13:1598520
Frontiers in cell and developmental biology 2025;13:1598520
Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.
Gong W, Wang Y, Li Q, Gao Y, Li J
Frontiers in molecular biosciences 2025;12:1557218
Frontiers in molecular biosciences 2025;12:1557218
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis.
Wang X, Li J, Qin R, Yin Y, Li J, Lin S, Zou X
Frontiers in molecular biosciences 2025;12:1523494
Frontiers in molecular biosciences 2025;12:1523494
POLR1A inhibits ferroptosis by regulating TFAM-mediated mitophagy and iron homeostasis.
Zhang T, Gao Y, Harhai M, Jourdain AA, Marti TM, Vassella E, Yang Z, Zhou Q, Dorn P, Peng RW
Redox biology 2025 Sep;85:103758
Redox biology 2025 Sep;85:103758
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
Jia H, Liu S, Wang W, He P, Zhao F, Xu X
Toxicology 2025 Sep;516:154197
Toxicology 2025 Sep;516:154197
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Chu G, Wang J, Wang Z, Cai X, Shi S, Qing Q, Zhong Y, Zhang Q
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
NAT10-Mediated N4-Acetylation of SLC7A11 mRNA Promotes Hepatocellular Carcinoma Progression and Metastasis by Repressing Ferroptosis.
Wang C, Liu J, Chang H, Wu Y, Chai Z, Jia P, Yuan Y, Tan L
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70496
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70496
Rutin Alleviates Breast Cancer Resistance to Tamoxifen By Downregulating ABC Transporters, Inducing ROS Generation and Resetting Redox Status.
Effat H, Radwan AM, Sharaky M, Abosharaf HA
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70490
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70490
Brucine Inhibits Gastric Cancer via Activation of Ferroptosis Through Regulating the NF-κB Signaling Pathway.
Zhang B, Yu C, Zhang S, Zhang M
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Journal of biochemical and molecular toxicology 2025 Sep;39(9):e70479
Dimethylmalonate induces ferroptosis by inhibiting the SUCNR1/PI3K/HIF-1α/SLC7A11 signaling axis in triple-negative breast cancer.
Huang W, Lin Q, Cao Y, Gong C, Jin L, Wang Y, Peng R
Biochemical pharmacology 2025 Sep;239:117051
Biochemical pharmacology 2025 Sep;239:117051
Alexidine dihydrochloride enhances the sensitivity of human hepatocellular carcinoma to disulfidptosis via ATF4-DDIT3 activation.
Li M, Xu J, Du K, Wang G, Feng Y, Liu P
Free radical biology & medicine 2025 Sep;237:585-599
Free radical biology & medicine 2025 Sep;237:585-599
β-elemene promotes ferroptosis to improve the sensitivity of imatinib in gastrointestinal stromal tumours by targeting N6AMT1.
Lan J, Zhang W, Zeng K, Li C, He J, Li X, Yang R, Chi J, Hong Z, Wang W, Zhou C, Xiao B, Fan W, Lin J, Ou Q, Fang Y, Pan Z, Peng J, Li W, Wu X
Clinical and translational medicine 2025 Sep;15(9):e70438
Clinical and translational medicine 2025 Sep;15(9):e70438
Alpha-Heredin targets CAMKⅡ/DRP1-Mediated mitochondrial fission to trigger ferroptosis in pancreatic ductal adenocarcinoma.
Li X, Si W, Zhang Y, Yang P, Ruan L, Ba H, Chen Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157048
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157048
Formononetin enhances cisplatin chemotherapy sensitivity in osteosarcoma by inducing ferroptosis and reconstructing the immune microenvironment.
Liu Y, Xie T, Liang J, Feng W, Yang M, Li S, Xiong L, Luo K, Li F, Tang S, Liu S, Huang Q, Tang H, Tang F, Wei Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156960
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156960
Neonatal necrotizing enterocolitis attenuates adult asthma via eosinophil ferroptosis.
Lai J, Zhang H, Li H, Li F, Huang D, Huang D, Zhao X, Wang Y, Jiang C, Huang R, Hao H, Wu B, Wu D
Cellular signalling 2025 Sep;133:111878
Cellular signalling 2025 Sep;133:111878
ROS-Responsive Hydrogel for Localized Delivery of Nampt and Stat3 Inhibitors Exhibits Synergistic Antitumor Effects in Colorectal Cancer Through Ferroptosis Induction and Immune Microenvironment Remodeling.
Ye C, Mi M, Shi S, Qi L, Weng S, Wang L, Lu Y, Chen C, Tan Y, Yang M, Guo C, Bai R, Fang X, Wang J, Yuan Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e06599
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e06599
TMAO regulates OTUB1-mediated SLC7A11 stability to promote NAFLD progression.
Zhong B, Zhu Q, Wei P, Wang X
Biochemical and biophysical research communications 2025 Sep 8;778:152352
Biochemical and biophysical research communications 2025 Sep 8;778:152352
FGF5 alleviates ferroptosis in renal tubular epithelial cells by inducing mitophagy under in vitro ischemia-reperfusion-like injury.
Lin D, Wu T, Huang H, Hong X
Journal of molecular histology 2025 Sep 6;56(5):299
Journal of molecular histology 2025 Sep 6;56(5):299
Mechanism of ferroptosis in hypoxia-induced pulmonary vascular remodeling in hypoxia pulmonary hypertension: a study based on the ACE2-Ang-(1-7)-Mas axis.
Abudukeremu A, Aikemu A, Yang T, Fang L, Shanahati D, Nijiati Y
Chemico-biological interactions 2025 Sep 5;418:111596
Chemico-biological interactions 2025 Sep 5;418:111596
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
Ma C, Wang J, Cui S, Xu R
European journal of pharmacology 2025 Sep 5;1002:177859
European journal of pharmacology 2025 Sep 5;1002:177859
lncRNA CASC9 stabilizes MUC1 by binding to U2AF2 to inhibit cellular ferroptosis and alleviate LPS-induced cell injury.
Chen K, Chen C, Chen S, Zheng X, Pan G, Liang Y
European journal of pharmacology 2025 Sep 5;1002:177818
European journal of pharmacology 2025 Sep 5;1002:177818
Ulinastatin protects against cisplatin-induced ovarian damage via Nrf2/Keap1 pathway.
Zhao L, Wu Y, Zhang X, Li Y, Li Y, Fu Z
Journal of ovarian research 2025 Sep 29;18(1):207
Journal of ovarian research 2025 Sep 29;18(1):207
BRD-K20733377 inhibits ferroptosis and alleviates intervertebral disc degeneration via the STAT3/NFKB1 axis: a multiapproach study.
Sun H, You X, Li Z, Li Z, Hua B, Liu C, Zhang Y, Wu H, Zai S, Zhang L
Stem cell research & therapy 2025 Sep 29;16(1):531
Stem cell research & therapy 2025 Sep 29;16(1):531
Extrachromosomal circular DNA drives ferroptosis and immunity in trophoblasts via the STING pathway in preeclampsia.
Wang X, Bian W, Huang M, Li T, Xiong H, Xiang S, Li H, Yang H, Yang H
Biochemical and biophysical research communications 2025 Sep 25;781:152522
Biochemical and biophysical research communications 2025 Sep 25;781:152522
Mechanism of xihuang pill inhibition of SLC7A11 deubiquitination through downregulation of the OTUB1 to promote ferroptosis in triple-negative breast cancer.
Qiu Y, Zhang G, Su R, Chen Y, Yi C, Zhan S, Zhang H, Liu T, Li J, Wu Y, Yan X, Ma M
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120456
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120456
Protecting the brain from stroke: Huoxue Rongluo formula (HXRLF) targets ferroptosis for neuroprotection.
Ma Q, Luo L, Liao Y, Yang R, Ouyang X, Zhang Y, Yan S, Gong C, Liu L, Zhou D
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120329
Journal of ethnopharmacology 2025 Sep 25;353(Pt A):120329
Peroxiredoxins as novel indicators in multiple myeloma associated with ferroptosis and immune infiltration.
Chen Y, Peng X, Feng Z, Zhang L, Bai J, Li Y, Li L, Zhang L
Scientific reports 2025 Sep 25;15(1):32765
Scientific reports 2025 Sep 25;15(1):32765
Self-assembled cyanidin-3-O-glucoside nanoparticles alleviate inflammation and ferroptosis induced by PRRSV infection.
Chen X, Pang Y, Amona FM, Liu Z, Wang F, Liang Y, Yang J, Zhang W, Fang X, Chen X
Journal of virology 2025 Sep 23;99(9):e0095425
Journal of virology 2025 Sep 23;99(9):e0095425
Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis.
Lin Y, Feng J, Zhao M, Zhang L, Li Y, Chen X, Lin C, Lin J, Lin Q, Li J, Wu L, Li L
ACS chemical biology 2025 Sep 19;20(9):2191-2203
ACS chemical biology 2025 Sep 19;20(9):2191-2203
Farrerol ameliorates diabetic cardiomyopathy by inhibiting ferroptosis via miR-29b-3p/SIRT1 signaling pathway in endothelial cells.
Guo Y, Yu XR, Gu HD, Wang YJ, Yang ZG, Chi JF, Zhang LP, Lin H
World journal of diabetes 2025 Sep 15;16(9):109553
World journal of diabetes 2025 Sep 15;16(9):109553
Entospletinib alleviates acute liver injury and acute kidney injury by inhibiting ferroptosis.
Zhao M, Lin Y, Zeng Q, Li Y, Feng J, Chen X, Lin C, Zhang L, Zhong Y, Lin J, Lin Q, Li J, Wu L, Liu X, Li L
European journal of pharmacology 2025 Sep 15;1003:177939
European journal of pharmacology 2025 Sep 15;1003:177939
TFAP2A-mediated Transcriptional Activation of ELMO1 Inhibits Ferroptosis and Promotes Esophageal Squamous Cell Carcinoma Progression.
Deng Z, Xu J, Liu Z
Molecular biotechnology 2025 Sep 13;
Molecular biotechnology 2025 Sep 13;
Aloperine ameliorates radiation enteritis by driving the TAS2R138-PLCβ/GAPDH axis-mediated glucose metabolic reprogramming to inhibit ferroptosis in intestinal epithelial cells.
Zeng X, Pang S, Lu H, Zhu J, Li Z, Liu N, Zhang X, Wang Y, Wei Z
Biochemical pharmacology 2025 Sep 1;242(Pt 1):117292
Biochemical pharmacology 2025 Sep 1;242(Pt 1):117292
Mycophenolate mofetil inhibits ferroptosis by boosting autophagy to prevent pulmonary fibrosis.
Liu W, Liu B, Lv C, Li H, Wang Y, Song X, Chen M
Archives of biochemistry and biophysics 2025 Oct;772:110553
Archives of biochemistry and biophysics 2025 Oct;772:110553
Glycyrrhizic Acid Ameliorates LPS-Induced WI-38 Cell Inflammation, Oxidative Stress, and Ferroptosis via Targeting METTL14 in Infantile Pneumonia.
Xie X, Wang C, Sun Y, Sun T, Song Y, Wang N, Wang Z, Wang Y
Clinical and experimental pharmacology & physiology 2025 Oct;52(10):e70068
Clinical and experimental pharmacology & physiology 2025 Oct;52(10):e70068
4-Octyl Itaconate Attenuates Postmenopausal Osteoporosis by Inhibiting Ferroptosis and Enhancing Osteogenesis via the Nrf2 Pathway.
Li Y, Li Y, Li P, Yang L, Li H
Inflammation 2025 Oct;48(5):3326-3339
Inflammation 2025 Oct;48(5):3326-3339
3D printed GelMA/HAMA based mechanical microenvironment boosted PDAC chemoresistance via NRF2-repressed ferroptosis.
Yan J, Wu D, Zhu B, Guan X, Zhang X, Guo Y, Lu Y
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114816
Colloids and surfaces. B, Biointerfaces 2025 Oct;254:114816
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610
Free radical biology & medicine 2025 Oct;238:595-610
Ferredoxin 1-like maintains iron homeostasis and hepatoma cell survival.
Zheng J, Zheng S, Zhou Q, Wu Y, Zhu C, Zheng Y, Li H, Li M, Zhong W, Yan D
Free radical biology & medicine 2025 Oct;238:52-63
Free radical biology & medicine 2025 Oct;238:52-63
CROT overactivation within peroxisomes confers chemoresistance to non-small cell lung cancer by targeting fatty acid oxidation-Nrf2-ferroptosis resistance axis.
Hua C, Zhang G, Yu W, Zhou J, Ru L, Xue G, Zheng L, Wang M, Wang Y, Yu D, Wang Q, Liu J, Wang R, Deng W, Tang R, Guo W
Pharmacological research 2025 Oct;220:107911
Pharmacological research 2025 Oct;220:107911
5-HT regulates resistance to aumolertinib by attenuating ferroptosis in lung adenocarcinoma.
Feng Y, He Y, Zuo R, Gong W, Gao Y, Wang Y, Wang Y, Chen W, Chen L, Luo Y, Yuan D, Chen P, Guo H
EMBO molecular medicine 2025 Oct;17(10):2586-2611
EMBO molecular medicine 2025 Oct;17(10):2586-2611
Panx3 mediates ferroptosis via the AKT/mTOR signaling pathway in oral squamous cell carcinoma.
Li X, Zhao Y, Liu Y, Zhang CS, Xu ZY, Wang SR, Zhang TM, Zhang Y, Liang SX, Yan YB
Cellular signalling 2025 Oct;134:111908
Cellular signalling 2025 Oct;134:111908
IL-6/KIAA1429 promotes ferroptosis resistance in endometrial cancer through m6A modification of DDIT3.
Shen X, Shu W, Zhang J, Zhou T, Dong K, Zhang J, Yao Y, Li H, Cheng S, Zhang T, Chen G, Yu S, Zhang Q, Wang H, Liu Y
Cellular signalling 2025 Oct;134:111906
Cellular signalling 2025 Oct;134:111906
PIEZO1-GPX4 Axis Mediates Mechanical Stress-Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation.
Chen F, Peng F, Chen S, Du Y, Li J, Fan Y, Cui Z, Gu G, Zhang H, Jiang Z, Wang G, Jing X, Dong J, Li T, Xi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e02052
TXNIP mediates ferroptosis in a bronchopulmonary dysplasia mouse model by regulating the SLC7A11/GPX4 pathway.
Chen D, Yin F, Yang P, Xia W, Huang Y, Feng Y, Yang L, Lin S, Zhang Q
Scientific reports 2025 Oct 8;15(1):35188
Scientific reports 2025 Oct 8;15(1):35188
SLC25A10 promotes cisplatin resistance by inhibiting ferroptosis in cervical cancer.
Ma C, Lu X, Ni C, Gao Y, Yang F, Chen S, Du Y, Zhao F, Cao Y, Huang H
Cell death discovery 2025 Oct 7;11(1):447
Cell death discovery 2025 Oct 7;11(1):447
Metabolic interplay between exogenous cystine and glutamine dependence in triple-negative breast cancer.
Ge Z, Wallace M, Turner R, Yin M, Rooney MF, Porter RK
Cell death discovery 2025 Oct 6;11(1):430
Cell death discovery 2025 Oct 6;11(1):430
Molecular subtypes and prognostic signature rooted in disulfidptosis highlight tumor microenvironment in lung adenocarcinoma.
Xia W, Liu J, Chen R, Feng J, Wu L, Wang Y, Wang X, Song C, Mao W
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2025 Oct 30;37(5):796-820
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2025 Oct 30;37(5):796-820
Integrated Multiomic Analysis Reveals the Therapeutic Potential of Danhong Injection in Mitigating Radiation-Induced Heart Disease by Modulating Ferroptosis.
Wang BW, Wang G, Zhang Z, Lu WJ, Li YL, Shu YB, Xie P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71106
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71106
Analysis of the Correlation Between Depression-like Behaviors and Lipid Peroxidation in the Prefrontal Cortex of Mice: The Impact of Early Life Stress.
Mi X, Ye ZL, Zhang XJ, Dai XM, Luo ZS
Brain sciences 2025 Oct 15;15(10)
Brain sciences 2025 Oct 15;15(10)
Lycium barbarum polysaccharide alleviates osteoarthritis progression in mice DMM model by inhibiting chondrocytes ferroptosis and promoting the gut Lactobacillus/Alistipes ratio.
Meng T, Wang J, Hou N, Wang Y, Gu Y, Lu M, Zheng S, Lu M
Molecular biology reports 2025 Oct 11;52(1):1021
Molecular biology reports 2025 Oct 11;52(1):1021
Mechanistic insights into the renoprotective effects of artesunate in cisplatin-induced acute kidney injury.
Chen H, Guo R, Zhang C, Zhang L, Hu H, Du P, Duan J, Chen L, Ma X, Xue J, Mao Y, Jiang T
Life sciences 2025 Oct 1;378:123820
Life sciences 2025 Oct 1;378:123820
Upregulation of ACSL1 in synovial macrophages promotes lipid peroxidation via the IκB/NF-κB pathway to accelerate osteoarthritis.
Yao Z, Yuan Z, Li Y, Li X, Peng C, Jin J, Zhang H, Bai X, Pan J, Cai D
Journal of orthopaedic translation 2025 Nov;55:360-375
Journal of orthopaedic translation 2025 Nov;55:360-375
Atraric acid attenuates chronic intermittent hypoxia-induced lung injury by inhibiting ferroptosis through activation of the NRF2 pathway.
Chen J, Zhou L, Li M, Wang J, Chen Y, Xia J, Lin Y, Chen H, Dong Z
Toxicology and applied pharmacology 2025 Nov;504:117540
Toxicology and applied pharmacology 2025 Nov;504:117540
NPB-1575 attenuates neuroinflammation and resists ferroptosis in rat ischemic stroke via IRS2 signaling pathway.
Li XN, Shang NY, Liu MY, Sui SY, Tang JS, Lan JQ, Kang YY, Zhang BD, Wen ZP, Feng XH, Wu L, Dai JG, Peng Y
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Acta pharmacologica Sinica 2025 Nov;46(11):2893-2907
Targeting ZNRF2-mediated SLC3A2 plasma membrane translocation enhances ferroptosis in lung adenocarcinoma.
Zhang W, Li J, Zhao J, Lu D, Zhang M, Ma C, Yang Y, Gu L, Zhu J, Zeng Y, Huang JA, Liu Z
Oncogene 2025 Nov;44(45):4339-4351
Oncogene 2025 Nov;44(45):4339-4351
ML385 increases ferroptosis via inhibiting Nrf2/HO-1 pathway to enhances the sensitivity of MCF-7 TAMR to tamoxifen.
Yuan J, Huang W, Lin M, Sun S, Zhong F, Ye L, Yin H, Ou X, Zeng Z
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):16081-16093
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):16081-16093
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
Ren R, Fan T, Li Y, Li C, Jin F, Gao H, Wang X, Xu Y, Li X, Li S, Liu H
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
SPINT2 inhibits NEDD4L-mediated ACSL4 ubiquitination to promote ferroptosis and suppress gallbladder cancer progression.
Ye P, Yang X, Wang H, Ren Y, Gao M, Wang Y, Guo Y, Sun Y, Xu J
International journal of biological macromolecules 2025 Nov;330(Pt 3):148141
International journal of biological macromolecules 2025 Nov;330(Pt 3):148141
Structural characterization and functional role of SLC7A6 in GSSG transport and Ferroptosis regulation.
Yan G, Chen M, Lu Z, Huang H, Wang X, Qin W, Mo S, Zhong P, Han C, Ye X
International journal of biological macromolecules 2025 Nov;330(Pt 3):148008
International journal of biological macromolecules 2025 Nov;330(Pt 3):148008
Bovine viral diarrhea virus E2 targets SLC3A2 to modulate lipid peroxidation for replication advantage.
Wu D, Rehman FU, Zheng J, Yang K, Jiang C, Xu X, Yuan X, Guo A
International journal of biological macromolecules 2025 Nov;329(Pt 1):147663
International journal of biological macromolecules 2025 Nov;329(Pt 1):147663
Exosomal CagA induces macrophage polarization and ferroptosis by JAK1-2/STAT1 signaling pathway in Helicobacter pylori-associated gastritis.
Lin J, Lu W, Cheng S, Zhang Z, Hu Y, Chen S, Li H, Chi J, Liu X, Guo Y, Xu C
Free radical biology & medicine 2025 Nov;239:91-103
Free radical biology & medicine 2025 Nov;239:91-103
Systemic aldehyde storm induced by allyl alcohol exposure results in extensive hepatic ferroptosis in Aldh2∗2 knock-in mice.
Takami Y, Nakamura J, Katahira J, Maeda Y, Tanaka M, Kuwamura M, Okada T, Izawa T
Free radical biology & medicine 2025 Nov;239:177-188
Free radical biology & medicine 2025 Nov;239:177-188
Botulinum Toxin Type A as a Therapeutic Agent in Epilepsy: Attenuation of Neuronal Ferroptosis and Cognitive Dysfunction.
Li S, Huang Z, Ma Y, Zheng Y, Du M, Lian Y
Brain and behavior 2025 Nov;15(11):e70930
Brain and behavior 2025 Nov;15(11):e70930
Cardiomyocyte-specific knockout of Oip5-as1 exacerbates MI/R-induced ferroptosis via p62/KEAP1/NRF2 inhibition.
Hu S, Chen C, Wei S, Bai M, Niu X
Cellular signalling 2025 Nov;135:112007
Cellular signalling 2025 Nov;135:112007
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
Chang X, Zhang Y, Wang Q, Yang W, Zhang R, Cong X, Xiao W, Piao J, Lin Z, Jin A
Cellular signalling 2025 Nov;135:111998
Cellular signalling 2025 Nov;135:111998
Downregulation of acetyl-CoA carboxylase induces ferroptosis and inhibits tumor growth in oral squamous cell carcinoma.
Xu Z, Jia G
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2025 Nov;100(8):451-459
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2025 Nov;100(8):451-459
Sestrin2 Exerts a Novel Protective Effect Against LPS-Induced Ferroptosis via the Nrf2-SLC7A11-GPX4 Signaling Axis.
Zhang X, Yin J, Yang Y, Peng J, Xu Y, Zhang W, Xiao H, Lu Z, Liu H, Wen Y, Liu M, Chen E, Zhang X, Guo S, Han L, Feng H, Zhao P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71251
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 30;39(22):e71251
Taoren Honghua Jian improves ferroptosis-mediated myocardial damage following myocardial infarction via Nrf2-dependent enhancement of GPX4/FSP1.
Zhang GY, Zhang F, Xie LP, Han X, Wang ZX, Wang WL, Peng Y, Xu HL, Xu T, Pang MJ, Liu B, Wang D, Zhou YC, Wu YT
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1726-1741
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1726-1741
Screening of key genes related to disulfidptosis in psoriasis based on the analysis of WGCNA.
Li Q, Xu P, Piao Y, Wang Z, Lv C
Scientific reports 2025 Nov 28;15(1):45579
Scientific reports 2025 Nov 28;15(1):45579
NAT10-mediated lipid metabolic reprogramming drives EGFR-TKI resistance in non-small cell lung cancer via ac4C-dependent mRNA stabilization.
Fang S, Zhu Y, Chen W, Mao W, Fang Y, Chen Z, Hong Z, Zhao X, Su W, Pan Y, Yao G, Wang J, Zhou C
Experimental hematology & oncology 2025 Nov 27;14(1):134
Experimental hematology & oncology 2025 Nov 27;14(1):134
miR-188-5p accelerates intervertebral disc degeneration by mediating P4HB to regulate ferroptosis in nucleus pulposus cells.
Yan J, Miao S, Zhu Y, Gao Y, Chen R, Gong Y, Zhou Q
European journal of medical research 2025 Nov 25;31(1):8
European journal of medical research 2025 Nov 25;31(1):8
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Peng H, Chang A, Zhang H, Xu X, Wang W, Zhang K, Yang J, Xie S, Peng X, Yin X, Qu C, Fu J, Ni J, Dong X
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Unveiling tectorigenin: A novel ferroptosis inducer targeting EGFR in bladder cancer.
Zhai J, Tan R, Yuan S, Che B, Xiong K, Lu L, Li Y, Wu C, Zhang Y, Zhang H, Tang K, Tang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157419
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157419
Jianpi Huayu decoction exerts antitumor effects in pancreatic cancer via SCD1-mediated lipid metabolism remodeling/ferroptosis axis.
Chen X, Ren Y, Yao R, Liu S, Fang C, Luo R, Shi H, Zhu X, Lai Y, Zhao X, Zhong C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157389
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157389
Verbascoside (VB) Inhibits Ischemic Stroke Progression via Suppression of Cell Damage and Ferroptosis By Targeting LCN2/ALOX5/SLC7A11/GPX4 Expression.
Zhang C, You J, Zhou X, Feng J, Li Q, Zhou H
Molecular neurobiology 2025 Nov 21;63(1):116
Molecular neurobiology 2025 Nov 21;63(1):116
Rescuing fertility: C-Phycocyanin prevents ovarian damage through NRF2-mediated ferroptosis pathways in polycystic ovary syndrome models.
Zhang J, Shen QS, Chen YX, Cheng HR, Zhang W, Xing T, Liu YJ, Cao YX, Liang D, Luo M, Yu B
Zoological research 2025 Nov 18;46(6):1531-1548
Zoological research 2025 Nov 18;46(6):1531-1548
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
Han B, Ma C, Liu Y, Shi C, Guo J, Bai M, Duan M, Meng S, Liu J, He M
Molecular neurobiology 2025 Nov 15;63(1):43
Molecular neurobiology 2025 Nov 15;63(1):43
BECN1 activator peptide Tat-beclin 1 promotes ferroptosis via the BECN1-SLC7A11 axis to inhibit NSCLC progression.
Gou J, Ma Y, Wu C, Zhang T, Jia T
Immunologic research 2025 Nov 13;73(1):163
Immunologic research 2025 Nov 13;73(1):163
NCOA4-mediated ferroptosis conducive to EMT inhibition in colorectal cancer cells was achieved through the PI3K/AKT/mTOR pathway.
Fu Y, Zhao Q, Li Y, Sun Y, He B, Li C, Zhang W, Yin Y, Li C
Scientific reports 2025 Nov 11;15(1):39542
Scientific reports 2025 Nov 11;15(1):39542
NRG1/PDGFC loop between fibroblasts and cancer cells drives paclitaxel resistance via ferroptosis suppression in breast cancer.
Duan WL, Wang XJ, Gu LH, Guo A, Ding YY, Lin P, Zhang BG
Cell death discovery 2025 Nov 10;11(1):520
Cell death discovery 2025 Nov 10;11(1):520
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Teng LS, Ying ZD, Sun XH, Hou HC, Qiu SD, Liu P, Li KJ, Zhang L, Sheng XH
Chemico-biological interactions 2025 Nov 1;421:111724
Chemico-biological interactions 2025 Nov 1;421:111724
Targeting PIM1 by Bruceine D attenuates skin fibrosis via myofibroblast ferroptosis.
Wang J, Song Y, Tan X, Wang T, Shi Y, Xu X, Du J, Yu Z, Song B
Redox biology 2025 May;82:103619
Redox biology 2025 May;82:103619
Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment.
Cheng Z, Hu Y, Liu Y, Wang X, Xue R, Cai K, Li L, Li M, Luo Z
Fundamental research 2025 May;5(3):1047-1062
Fundamental research 2025 May;5(3):1047-1062
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Xiong X, Huang H, Wang N, Zhou K, Song X
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Alkannin triggered apoptosis and ferroptosis in gastric cancer by suppressing lipid metabolism mediated by the c-Fos/SREBF1 axis.
Yu H, Kou Q, Yuan H, Qi Y, Li Q, Li L, Zhao G, Wang G, Li S, Qu J, Chen H, Zhao M, Wang Q, Li S, Chen K, Lu C, Xiao H, Lin P, Li K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156604
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156604
Resveratrol Promotes Wound Healing by Enhancing Angiogenesis via Inhibition of Ferroptosis.
Pan Y, Xia M, Luo J, Lu S
Food science & nutrition 2025 May;13(5):e70254
Food science & nutrition 2025 May;13(5):e70254
Human antigen R -mediated autophagy-related gene 3 methylation enhances autophagy-driven ferroptosis in Crohn's disease colitis.
Li Z, Chang Y, He D, Dong K, Zhang H, Wang S
International immunopharmacology 2025 May 8;154:114565
International immunopharmacology 2025 May 8;154:114565
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
Gao L, Chang X, Han Y, Li J, Meng Y, Yang X, Jiang Z
International immunopharmacology 2025 May 8;154:114490
International immunopharmacology 2025 May 8;154:114490
HSPA9 contributes to tumor progression and ferroptosis resistance by enhancing USP14-driven SLC7A11 deubiquitination in multiple myeloma.
Shen N, Xia Y, Shen X, Hua W, Shi M, Chen L
Cell reports 2025 May 27;44(5):115720
Cell reports 2025 May 27;44(5):115720
METTL9 mediated N1-Histidine methylation of SLC39A7 confers ferroptosis resistance and inhibits adipogenic differentiation in mesenchymal stem cells.
Jin J, Li Q, Zhang Y, Ji P, Wang X, Zhang Y, Yuan Z, Jiang J, Tian G, Cai M, Feng P, Wu Y, Wang P, Liu W
Molecular medicine (Cambridge, Mass.) 2025 May 26;31(1):206
Molecular medicine (Cambridge, Mass.) 2025 May 26;31(1):206
Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.
Xu X, Zhang H, Chang A, Peng H, Li S, Zhang K, Wang W, Yin X, Qu C, Dong X, Ni J
International journal of molecular sciences 2025 May 24;26(11)
International journal of molecular sciences 2025 May 24;26(11)
Turning Waste into Treasure: Radiation Byproduct-Induced Fe(III)/Fe(II) Conversion for Efficient Ferroptosis to Improve Iodine-131-Based Transarterial Radioembolization for Liver Tumors.
Xu J, Luo X, Su W, Jia G, Cai H, Li D, Li R, Wang X, Yang Y, Wang T, Zuo C
ACS applied materials & interfaces 2025 May 21;17(20):29170-29182
ACS applied materials & interfaces 2025 May 21;17(20):29170-29182
NCOA5 induces sorafenib resistance in hepatocellular carcinoma by inhibiting ferroptosis.
Gao S, Fan L, Wang H, Wang A, Hu M, Zhang L, Sun G
Cell death discovery 2025 May 2;11(1):215
Cell death discovery 2025 May 2;11(1):215
Inhibition of TPI1 Sensitizes Cisplatin-Resistant Oral Cancer to Ferroptosis.
Wang D, Zheng H, Chen Y, Hao J, Zhou Y, Li N
Biomedicines 2025 May 19;13(5)
Biomedicines 2025 May 19;13(5)
Inhibition of ULK1 attenuates ferroptosis-mediated cardiac hypertrophy via HMGA2/METTL14/SLC7A11 axis in mice.
Zhang M, Sha Y, Wang J, Qi H, Shi P, Liu Y, Jiang M, Ba L, Liu Y, Cao Y, Zhang Q, Sun H
European journal of pharmacology 2025 May 15;995:177416
European journal of pharmacology 2025 May 15;995:177416
The STEAP4 target NQO1 mediates colon tumorigenesis.
Yin K, Villareal L, Wu X, Arcos M, Lee J, Martin DR, In JG, Leslie K, Zhang DD, Xue X
Journal of cell science 2025 May 15;138(10)
Journal of cell science 2025 May 15;138(10)
Cohabitation facilitates microbiome shifts that promote isoflavone transformation to ameliorate liver injury.
Zeng Y, Wu R, He Y, Zhang Q, Wang Z, Qin P, Yang F, Han Y, Hao M, Zheng Y, Gao L, Chen X, Zhao X, Zeng Z, Lian ZX, Xiao W, Liu Z, Zhao ZB, Gong S
Cell host & microbe 2025 May 14;33(5):688-704.e10
Cell host & microbe 2025 May 14;33(5):688-704.e10
Platelet-Rich Plasma-Derived Exosome-Encapsulated Hydrogels Accelerate Diabetic Wound Healing by Inhibiting Fibroblast Ferroptosis.
Wang S, Wu J, Ren K, Zhang Y, Gao F, Chen Y, Chen C, Lu J
ACS applied materials & interfaces 2025 May 14;17(19):27923-27936
ACS applied materials & interfaces 2025 May 14;17(19):27923-27936
TRIM21 knockdown alleviates hemorrhage induced hepatic ischemia reperfusion injury by suppressing ferroptosis-induced NETs.
Wang S, Li Z, Chang Y, He D, Dong K, Cheng X
Scientific reports 2025 May 14;15(1):16731
Scientific reports 2025 May 14;15(1):16731
Deciphering the Role of Ferroptosis in the Pathogenesis of Peripheral Artery Disease Myopathy.
Wilkinson T, Fletcher E, Ring A, Bradley C, Papoutsi E, Miserlis D, Smith RS, Bohannon WT, Pipinos II, Koutakis P
Biology 2025 May 12;14(5)
Biology 2025 May 12;14(5)
Erythrocyte Membrane-Camouflaged Xanthohumol Nanoparticles Mitigate Doxorubicin-Induced Cardiotoxicity by Inhibiting Ferroptosis.
Li J, Zeng Y, Liu F, Liao X, Zhong C, Dong S, Cai Y, Yang P
ACS biomaterials science & engineering 2025 May 12;11(5):2727-2738
ACS biomaterials science & engineering 2025 May 12;11(5):2727-2738
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
Lu Q, Shao N, Fang Z, Ouyang Z, Shen Y, Yang R, Liu H, Cai B, Wei T
Chemico-biological interactions 2025 May 1;412:111459
Chemico-biological interactions 2025 May 1;412:111459
Integration of Bioinformatics and Machine Learning Strategies Identifies Ferroptosis and Immune Infiltration Signatures in Peri-Implantitis.
Huang J, Zou Y, Deng H, Zha J, Pathak JL, Chen Y, Ge Q, Wang L
International journal of molecular sciences 2025 May 1;26(9)
International journal of molecular sciences 2025 May 1;26(9)
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.
Li W, Han J, Huang B, Xu T, Wan Y, Luo D, Kong W, Yu Y, Zhang L, Nian Y, Chu B, Yin C
The EMBO journal 2025 Mar;44(6):1641-1662
The EMBO journal 2025 Mar;44(6):1641-1662
Lactate Dehydrogenase A Is a Novel Positive Regulator of Vascular Smooth Muscle Cell Ferroptosis During Aortic Dissection.
Feng X, Yi X, Huo B, Luo H, Chen J, Guo X, Fang ZM, Gong FH, Wei X, Jiang DS, Chen Y
Antioxidants & redox signaling 2025 Mar;42(7-9):378-392
Antioxidants & redox signaling 2025 Mar;42(7-9):378-392
USP13 facilitates a ferroptosis-to-autophagy switch by activation of the NFE2L2/NRF2-SQSTM1/p62-KEAP1 axis dependent on the KRAS signaling pathway.
Chen L, Ning J, Linghu L, Tang J, Liu N, Long Y, Sun J, Lv C, Shi Y, Tao T, Xiao D, Cao Y, Wang X, Liu S, Li G, Zhang B, Tao Y
Autophagy 2025 Mar;21(3):565-582
Autophagy 2025 Mar;21(3):565-582
p53 inhibits OTUD5 transcription to promote GPX4 degradation and induce ferroptosis in gastric cancer.
Zhang J, Tian T, Li X, Xu K, Lu Y, Li X, Zhao X, Cui Z, Wang Z, Zhou Y, Xu Y, Li H, Zhang Y, Du Y, Lv L, Xu Y
Clinical and translational medicine 2025 Mar;15(3):e70271
Clinical and translational medicine 2025 Mar;15(3):e70271
Targeting YBX1-m5C mediates RNF115 mRNA circularisation and translation to enhance vulnerability of ferroptosis in hepatocellular carcinoma.
Li O, An K, Wang H, Li X, Wang Y, Huang L, Du Y, Qin N, Dong J, Wei J, Sun R, Shi Y, Guo Y, Sun X, Yang Y, Yang YG, Kan Q, Tian X
Clinical and translational medicine 2025 Mar;15(3):e70270
Clinical and translational medicine 2025 Mar;15(3):e70270
Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways.
Zhang M, Guan X, Dong Z, Yang C, Xiong C, Cheng W, Shang A, Liu Y, Guo X, Zhang B, Zhang B, Jin S, Qi W, Alexandrovna BT, Jiang Y, Du Z, Xu C
Clinical and translational medicine 2025 Mar;15(3):e70247
Clinical and translational medicine 2025 Mar;15(3):e70247
HMGB1 secretion by resveratrol in NSCLC: A pathway to ferroptosis-mediated platelet activation suppression.
Zhang Y, Bao S, Zeng J, Liu J, Li X, Zhang B, Wang H, Cheng Y, Zhang H, Xia W, Zu L, Xu X, Xu S, Song Z
Cellular signalling 2025 Mar;127:111607
Cellular signalling 2025 Mar;127:111607
The Lactate-Primed KAT8‒PCK2 Axis Exacerbates Hepatic Ferroptosis During Ischemia/Reperfusion Injury by Reprogramming OXSM-Dependent Mitochondrial Fatty Acid Synthesis.
Yuan J, Yang M, Wu Z, Wu J, Zheng K, Wang J, Zeng Q, Chen M, Lv T, Shi Y, Yang J, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2414141
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2414141
Gaudichaudione H Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Disulfidptosis via Regulating NRF2-SLC7A11 Signaling Pathway.
Shi M, Li X, Guo Y, Zhang Y, Xu J, Yan L, Liu R, Wang H, Tang S, Zhao Y, Li Z, Feng Y, Ren D, Liu P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(11):e2411131
Moscatilin Induces Ferroptosis in Clear Cell Renal Cell Carcinoma via the JAK-STAT Signaling Pathway.
Chen P, Yang J, Chen L, Liu C, Li Z, Long X, Wu J, Wu B, Wu J
Chemical biology & drug design 2025 Mar;105(3):e70071
Chemical biology & drug design 2025 Mar;105(3):e70071
Induction of UBQLN1-mediated PGC1α stability by isoliensinine overcame hypoxia-induced resistance in liver cancer cells.
Xu X, Li W, Zhou Y, Wang M, Ji S, Xia S, Li Y, Guo X, Huan S, Wang F, Zhang F, Cheng H, Yin G, Zheng S
BioFactors (Oxford, England) 2025 Mar-Apr;51(2):e70008
BioFactors (Oxford, England) 2025 Mar-Apr;51(2):e70008
AC129507.1 is a ferroptosis-related target identified by a novel mitochondria-related lncRNA signature that is involved in the tumor immune microenvironment in gastric cancer.
Yu S, Liang J, Liu L, Chen M, Chen C, Zhou D
Journal of translational medicine 2025 Mar 6;23(1):290
Journal of translational medicine 2025 Mar 6;23(1):290
ALPK1 signaling pathway activation by HMGB1 drives microglial pyroptosis and ferroptosis and brain injury after acute ischemic stroke.
Du O, Yan YL, Yang HY, Yang YX, Wu AG, Guo YK, Li K, Qiao G, Du JR, Long FY
International immunopharmacology 2025 Mar 6;149:114229
International immunopharmacology 2025 Mar 6;149:114229
Edaravone dextranol alleviates ferroptosis, Cuproptosis, and blood-brain barrier damage after acute cerebral infarction.
Jin G, Han W, Duan T, Xue Z, Song C, Xu Y, Yu M
Metabolic brain disease 2025 Mar 3;40(3):134
Metabolic brain disease 2025 Mar 3;40(3):134
ROS-responsive nanoparticles with selenomethionine for ferroptosis modulation in abdominal aortic aneurysm.
He H, Chen L, Peng J, Guo J, Xiao X, Dou C, Chen H, Zhan S, Han X, Yao W
iScience 2025 Mar 21;28(3):111880
iScience 2025 Mar 21;28(3):111880
Increased melanin induces aberrant keratinocyte - melanocyte - basal - fibroblast cell communication and fibrogenesis by inducing iron overload and ferroptosis resistance in keloids.
Shi X, Xia X, Xiao Y, Zhang Y, Gong Y, Chen Y, Shi C, Wang W, Liu J, Huang J, Liu M, Xu Z, Ma Y, Shi M, Wang J, Wu W
Cell communication and signaling : CCS 2025 Mar 18;23(1):141
Cell communication and signaling : CCS 2025 Mar 18;23(1):141
Monounsaturated fatty acids promote cancer radioresistance by inhibiting ferroptosis through ACSL3.
Cao Y, Li J, Chen Y, Wang Y, Liu Z, Huang L, Liu B, Feng Y, Yao S, Zhou L, Yin Y, Huang Z
Cell death & disease 2025 Mar 18;16(1):184
Cell death & disease 2025 Mar 18;16(1):184
Smilax glabra Flavonoids Inhibit AMPK Activation and Induce Ferroptosis in Obesity-Associated Colorectal Cancer.
Xu J, Cai Z, Pang Z, Chen J, Zhu K, Wang D, Tu J
International journal of molecular sciences 2025 Mar 10;26(6)
International journal of molecular sciences 2025 Mar 10;26(6)
Bisphenol F induces spermatogenic cell ferroptosis via FTO-mediated m6A regulation of FTH1.
Zhou SM, Shi Y, Li JY, Wang N, Zeng Y, Chen HQ, Tan YP, Deng SW, Liu QQ, Huang XQ, Wang YQ, Zhou ZY, Liu WB
Free radical biology & medicine 2025 Mar 1;229:364-373
Free radical biology & medicine 2025 Mar 1;229:364-373
Cyclic vinyl sulfones activate NRF2 to protect from oxidative stress-induced programmed necrosis.
Davidovich P, Nikolaev D, Khadiullina R, Gurzhiy V, Bulatov E
Bioorganic & medicinal chemistry letters 2025 Mar 1;117:130058
Bioorganic & medicinal chemistry letters 2025 Mar 1;117:130058
Ceftriaxone affects ferroptosis and alleviates glial cell activation in Parkinson's disease.
Zhi H, Wang X, Chen Y, Cai Z, Li J, Guo D
International journal of molecular medicine 2025 Jun;55(6)
International journal of molecular medicine 2025 Jun;55(6)
CBX3 promotes multidrug resistance by suppressing ferroptosis in colorectal carcinoma via the CUL3/NRF2/GPX2 axis.
Bai X, Duan T, Shao J, Zhang Y, Xing G, Wang J, Liu X, Wang M, He Y, Wang H, Zhang ZY, Ni M, Zhou JY, Pan J
Oncogene 2025 Jun;44(22):1678-1693
Oncogene 2025 Jun;44(22):1678-1693
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment.
Yan Y, Hu J, Han N, Li HT, Yang X, Li LG, Xu Z, Xia F, Li J, Li TF, Chen R
Materials today. Bio 2025 Jun;32:101848
Materials today. Bio 2025 Jun;32:101848
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Yi G, Li M, Zhou J, Li J, Song X, Li S, Liu J, Zhang H, Chen Z
Materials today. Bio 2025 Jun;32:101697
Materials today. Bio 2025 Jun;32:101697
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
IGF2BP1/AIFM2 axis regulates ferroptosis and glycolysis to drive hepatocellular carcinoma progression.
Peng W, Liang J, Qian X, Li M, Nie M, Chen B
Cellular signalling 2025 Jun;130:111660
Cellular signalling 2025 Jun;130:111660
Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.
Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325
Antitumor/anti-inflammatory effects/tissue healing as an all-in-one therapeutic strategy for nasopharyngeal carcinoma.
Ni F, Lv H, Lin L, Zhang Y, Qiao Y, Zhang X, Li Z, Wang X, Dai X, Dong J
Journal of nanobiotechnology 2025 Jun 9;23(1):431
Journal of nanobiotechnology 2025 Jun 9;23(1):431
Mechanistic evaluation of a traditional herbal decoction in attenuating hepatic fibrosis via Nrf2/GPX4 pathway activation and ferroptosis inhibition.
Liu JJ, Zhou XQ, Zhou JL, Tong LJ, Hu LX, Liu X, Hu LM, Zhou CX, Dai Q
Hereditas 2025 Jun 9;162(1):100
Hereditas 2025 Jun 9;162(1):100
Network pharmacology analysis reveals that coumestrol targets ZYX to inhibit ferroptosis and alleviate acute pancreatitis.
Chen J, Xu H, Gao L, Niu L, Huang Z, Liu S, Huang S, Chen Y, Li J, Tan P, Fu W
International immunopharmacology 2025 Jun 26;159:114948
International immunopharmacology 2025 Jun 26;159:114948
Mitigating PCOS progression: The protective effect of C-phycocyanin on ovarian granulosa cell pyroptosis via the NRF2/NLRP3/GSDMD pathway.
Zhang J, Chen Y, Han B, Liu Y, Li X, Yang J, Liu Y, Cao Y, Liang D, Yu B
International immunopharmacology 2025 Jun 26;159:114917
International immunopharmacology 2025 Jun 26;159:114917
Cyanidin-3-O-glucoside mitigates Staphylococcus aureus-induced mastitis by suppressing inflammatory responses and Ferroptosis mediated by SESN2/Nrf2.
Pang Y, Ke Y, Amona FM, Chen X, Liu Z, Chen J, Liang Y, Wang F, Wang Y, Fang X, Chen X, Zhang C
International immunopharmacology 2025 Jun 26;159:114868
International immunopharmacology 2025 Jun 26;159:114868
Circular Shear Printing of Spiral-Oriented CF-PP Components for Enhanced Mechanical Performance and Warp Mitigation.
Mi D, Yang T, Jiang J, Bai H, Jia S
Polymers 2025 Jun 22;17(13)
Polymers 2025 Jun 22;17(13)
CISD2 ameliorates heatstroke-associated early cognitive deficits by inhibiting ferroptosis and maintaining dendritic spine density in hippocampal neurons in mice.
Zeng L, Sun J, Ji K, Zhang L, Niu J, Ma K, Yan Y, Hei Z, Sun Y
Neuroscience 2025 Jun 21;577:282-299
Neuroscience 2025 Jun 21;577:282-299
The upregulation of TNKS1 drives the phenotypic switching of vascular smooth muscle cells in aortic dissection through the activation of ferroptosis.
Xu X, Lin W, Liu T, Yuan C, Yan Y, Diao Y, Xiong J, Shao Y, Ni B
International immunopharmacology 2025 Jun 17;158:114722
International immunopharmacology 2025 Jun 17;158:114722
Targeting SIX2 as a novel sensitization strategy of sorafenib treatment on advanced hepatocellular carcinoma through modulating METTL9-SLC7A11 axis.
Lu J, Cai D, Qian L, Wang Y, Ai S, Song P, Sun F, Sun Y, Liang M, Jiang H, Wang X, Wang M, Lu X, Guan W, Shen X
NPJ precision oncology 2025 Jun 16;9(1):186
NPJ precision oncology 2025 Jun 16;9(1):186
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
Liu W, Zhou X, Xiao L, Huang X, Chang D, Zhong X, Zeng M, Xian Y, Zheng Y, Huang W, Huang R, Huang M
Chinese medicine 2025 Jun 10;20(1):83
Chinese medicine 2025 Jun 10;20(1):83
BTN3A2 interacted with MFGE8 to alleviate preeclampsia by promoting ferroptosis and inhibiting angiogenesis.
Yuan X, Wang Q, Hu C, Yong W, Li P
Life sciences 2025 Jun 1;370:123584
Life sciences 2025 Jun 1;370:123584
Ferulic acid/GRB2/NF-κB signaling pathway that alleviates ferroptosis-induced apoptosis of nucleus pulposus cells is a potential mechanism for intervertebral disc degeneration.
Li M, Liu X
Journal of orthopaedics 2025 Jul;65:302-309
Journal of orthopaedics 2025 Jul;65:302-309
MGST1 Inhibits Sevoflurane-Induced Ferroptosis and Activates the Wnt Pathway in HT22 Cells.
Gao S, Wang X, Shao Z, Chen J
Molecular neurobiology 2025 Jul;62(7):9497-9505
Molecular neurobiology 2025 Jul;62(7):9497-9505
Aerobic Exercise Activates Fibroblast Growth Factor 21 and Alleviates Cardiac Ischemia/Reperfusion-induced Neuronal Oxidative Stress and Ferroptosis in Paraventricular Nucleus.
Zhao Y, Feng L, Wu C, Xu Y, Bo W, Di L, Pan S, Cai M, Tian Z
Molecular neurobiology 2025 Jul;62(7):8484-8501
Molecular neurobiology 2025 Jul;62(7):8484-8501
Carfilzomib promotes Iodine-125 seed radiation-induced apoptosis, paraptosis, and ferroptosis in esophageal squamous cell carcinoma by aggravating endoplasmic reticulum stress.
Wang C, Zha YL, Wang H, Sun B, Qiang WG, Yuan Y, Shi HB, Hu WW
Translational oncology 2025 Jul;57:102393
Translational oncology 2025 Jul;57:102393
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
Li F, Qi Q, Qiao Y, Huang Y, Lu Y, Gu K, Liu H, Gao C, Liu S, Wu H
International journal of molecular medicine 2025 Jul;56(1)
International journal of molecular medicine 2025 Jul;56(1)
SPATA2/CYLD Pathway-Dependent Deubiquitylation of p53 Promotes Ferroptosis in Rat Heart After Ischaemia/Reperfusion Through Suppression of SLC7A11.
Duan DQ, Li MR, Lu LQ, Yao BF, Huang LL, Luo XJ, Peng J
Heart, lung & circulation 2025 Jul;34(7):719-729
Heart, lung & circulation 2025 Jul;34(7):719-729
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Ma MQ, Yang C, Jin SY, Yang Y, Pan YY, Lin XH
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Identification of FADS2 as a Contributor of Ferroptosis Escape in Bladder Cancer.
Li P, Yao S, Qi W, Liu H, Zhang X, Zhou B, Zhang S, Zhang Y, Liang H, Huang H, Zhao Y, Shi B, Chen J, Liu J
Journal of cellular and molecular medicine 2025 Jul;29(14):e70710
Journal of cellular and molecular medicine 2025 Jul;29(14):e70710
Methionine sulfoxide reductase A deficiency aggravated ferroptosis in LPS-induced acute kidney injury by inhibiting the AMPK/NRF2 axis and activating the CaMKII/HIF-1α pathway.
Yang L, Xiao JJ, Zhang L, Lu Q, Hu BB, Liu Y, Pu JX, Hu JW, Yu H, Wu X, Zhang BF
Free radical biology & medicine 2025 Jul;234:248-263
Free radical biology & medicine 2025 Jul;234:248-263
Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity.
Yao R, Zeng Y, Zhang Y, Cao X, Mao J, Li W, Xu K, Liu L
Cellular signalling 2025 Jul;131:111767
Cellular signalling 2025 Jul;131:111767
Apatinib combined with paclitaxel suppresses synergistically TNBC progression through enhancing ferroptosis susceptibility regulated SLC7A11/GPX4/ACSL4 axis.
Ma X, Cao D, Zhang Y, Ding X, Hu Z, Wang J
Cellular signalling 2025 Jul;131:111760
Cellular signalling 2025 Jul;131:111760
Exploring the molecular mechanisms through which overexpression of TET3 alleviates liver fibrosis in mice via ferroptosis in hepatic stellate cells.
Liu Y, Feng LL, Han B, Cai LJ, Liu RY, Tang S, Yang Q
Cellular signalling 2025 Jul;131:111747
Cellular signalling 2025 Jul;131:111747
Fucoxanthin Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Mice via Nrf2/HO-1/GPX4-Mediated Ferroptosis Pathway.
Liu Z, Ye J, Xi J, Li Q, Tang Y, Tian Y, Wang D, Yang Z, Ding Y
Food science & nutrition 2025 Jul;13(7):e70589
Food science & nutrition 2025 Jul;13(7):e70589
Targeting myeloid differentiation protein 2 ameliorates rheumatoid arthritis by inhibiting inflammation and ferroptosis via MAPK and NF-κB signaling pathways.
Zhou L, Yang T, Zhang S, Liu D, Feng C, Ni J, Shi Q, Liu Y, Meng Y, Zhu Y, Tang H, Wang J, Ma A
Journal of molecular medicine (Berlin, Germany) 2025 Jul;103(7):821-836
Journal of molecular medicine (Berlin, Germany) 2025 Jul;103(7):821-836
Transcription factor TCF3 promotes bladder cancer development via TMBIM6-Ca(2+)-dependent ferroptosis.
Yang WF, Guo WM, Luo QT, Lu J, Tan ZK, Ye YC, Fan G
Cell death discovery 2025 Jul 3;11(1):303
Cell death discovery 2025 Jul 3;11(1):303
Cadmium Inhibits Proliferation of Human Bronchial Epithelial BEAS-2B Cells Through Inducing Ferroptosis via Targeted Regulation of the Nrf2/SLC7A11/GPX4 Pathway.
Li H, Qiu Z, Chen L, Zhang T, Wei D, Chen X, Wang Y
International journal of molecular sciences 2025 Jul 25;26(15)
International journal of molecular sciences 2025 Jul 25;26(15)
Ponicidin triggered ferroptosis in esophageal squamous cell carcinoma by suppressing the SLC7A11/Glutathione/GPX4 signalling axis.
Liu W, Zhang J, Wu M, Ren D, Chen C, Du Z, Li Q, Chang J, Pu Q, Liu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156925
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156925
Caffeic acid phenethyl ester protects renal tubular epithelial cells against ferroptosis in diabetic kidney disease via restoring PINK1-mediated mitophagy.
Lu Y, Zhu Y, Feng S, Cong Q, Chen S, Zeng Y, Song K, Hu J
Molecular medicine (Cambridge, Mass.) 2025 Jul 24;31(1):264
Molecular medicine (Cambridge, Mass.) 2025 Jul 24;31(1):264
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Wang S, Zhu L, Wang Y, Han Y, Wang Q, Yang W, Zhao L, Zhang Y, Pei D, Huang W, Jin A, Lin Z, Piao J
Cell death & disease 2025 Jul 23;16(1):549
Cell death & disease 2025 Jul 23;16(1):549
Large-sized polystyrene microplastics induce oxidative stress in AML12 cells.
Zhao B, Liu R, Guo S, Li S, Huang Z, Wang Y, Yu C, Hou Z, Zhang Y, Zhang Y, Liu X
Scientific reports 2025 Jul 22;15(1):26616
Scientific reports 2025 Jul 22;15(1):26616
The SDF-1α/MTDH axis inhibits ferroptosis and promotes the formation of anti-VEGF-resistant choroidal neovascularization by facilitating the nuclear translocation of SREBP1.
Zou R, Zhang X, Dai X, Yuan Y, Dai J, Yuan F
Cell biology and toxicology 2025 Jul 17;41(1):118
Cell biology and toxicology 2025 Jul 17;41(1):118
Irisin prevents liver injury during exhausting physical activity by suppressing ferroptosis via Nrf2/GPX4 signaling.
Li Z, Wang B, Li X
BMC gastroenterology 2025 Jul 11;25(1):516
BMC gastroenterology 2025 Jul 11;25(1):516
Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
Wu F, Song C, Yin H, Chen R, Huang G, Zhang J, Chen H, Lin L, Yin J, Xie L, Liu W
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113814
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113814
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways.
Liu X, Chen Y, Zhang L, Qi Z, Yang L, Huang C, Wang L, Lin D
Antioxidants (Basel, Switzerland) 2025 Jul 10;14(7)
Antioxidants (Basel, Switzerland) 2025 Jul 10;14(7)
Trim65 mitigates doxorubicin-induced myocardial injury by reducing ferroptosis.
Ma X, Chen W, Hu Z, Xie L, Li Z, Liu H, Li Z, Jiang Z, Huang J, Jiang C, Huang K, Xiao S
Experimental cell research 2025 Jul 1;450(1):114613
Experimental cell research 2025 Jul 1;450(1):114613
The role of SLC7A11 in arsenite-induced oncogenic phenotypes of human bronchial epithelial cells: A metabolic perspective.
Fang X, Ruan Y, Yin X, Wang J, Chen C, Hu Y, Wang H, Pi J, Xu Y
Environmental pollution (Barking, Essex : 1987) 2025 Jul 1;376:126381
Environmental pollution (Barking, Essex : 1987) 2025 Jul 1;376:126381
TBBPA-BDBPE induces ferroptosis in trophoblasts through chaperone-mediated autophagy of GPX4.
Mu Y, Wang K, Kang Y, Fang Z, Yu S, Zhou J, Li S, Zhang M
Ecotoxicology and environmental safety 2025 Jul 1;299:118425
Ecotoxicology and environmental safety 2025 Jul 1;299:118425
SLC10A3 regulates ferroptosis of glioblastoma through the STAT3/GPX4 pathway.
Sun Q, Lu H, Yuan F, Zhao Q, Wei Y, Wang R, Chen Q, Liu B
Scientific reports 2025 Jul 1;15(1):21259
Scientific reports 2025 Jul 1;15(1):21259
Leveraging diverse cell death patterns in osteosarcoma patients and identification of the function of FADS2 in osteosarcoma cells.
Bai G, Zhao S, Chen L, Zhao M, Chen W
Scientific reports 2025 Jul 1;15(1):20831
Scientific reports 2025 Jul 1;15(1):20831
cDTL contributes to breast cancer progression through regulating redox homeostasis via affecting the function of system xc().
Wang S, Liu L, Li X, Li Q, Wang Y, Feng X
Biochemical and biophysical research communications 2025 Jan;744:151196
Biochemical and biophysical research communications 2025 Jan;744:151196
LRRC45 accelerates bladder cancer development and ferroptosis inhibition via stabilizing NRF2 by competitively KEAP1 interaction.
Fan L, Guo D, Zhu C, Gao C, Wang Y, Yin F, Liu M, Zhou Y, Wei T, Xiong X, Yu K, Le A
Free radical biology & medicine 2025 Jan;226:29-42
Free radical biology & medicine 2025 Jan;226:29-42
Lipoxin A4 suppresses neutrophil extracellular traps formation through the FPR2-dependent regulation of METTL3 in ischemic stroke.
Wei N, Lu T, Gu J, Cai H
Brain research bulletin 2025 Jan;220:111178
Brain research bulletin 2025 Jan;220:111178
The synergistic protective effects of paeoniflorin and β-ecdysterone against cardiac hypertrophy through suppressing oxidative stress and ferroptosis.
Yan P, Li X, He Y, Zhang Y, Wang Y, Liu J, Ren S, Wu D, Zhao Y, Ding L, Jia W, Lyu Y, Xiao D, Lin S, Lin Y
Cellular signalling 2025 Jan;125:111509
Cellular signalling 2025 Jan;125:111509
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Effect of different dietary oil sources on the performance, egg quality and antioxidant capacity during the late laying period.
Xu M, Liu L, Fan Z, Niu L, Ning W, Cheng H, Li M, Huo W, Zhou P, Deng H, Chen W, Che L
Poultry science 2025 Jan;104(1):104615
Poultry science 2025 Jan;104(1):104615
Bardoxolone methyl triggers Ferroptosis in cardiomyocytes.
Li H, Hong M, Liu Y, Rahman SU, Li X, Zheng F
Human & experimental toxicology 2025 Jan-Dec;44:9603271251394706
Human & experimental toxicology 2025 Jan-Dec;44:9603271251394706
Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.
Liu MJ, Xu ZP, Guan YQ, Wang YY, Wen XS, Li GH, Wang XN, Shen T
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118776
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118776
Enhanced glycolysis-derived lactate promotes microglial activation in Parkinson's disease via histone lactylation.
Qin Q, Wang D, Qu Y, Li J, An K, Mao Z, Li J, Xiong Y, Min Z, Xue Z
NPJ Parkinson's disease 2025 Jan 3;11(1):3
NPJ Parkinson's disease 2025 Jan 3;11(1):3
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Liu M, Xie WJ, Zhang X, Wu W, Li G, Wang L
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Targeting estrogen-regulated system x(c)(-) promotes ferroptosis and endocrine sensitivity of ER+ breast cancer.
Cao J, Zhou T, Wu T, Lin R, Huang J, Shi D, Yu J, Ren Y, Qian C, He L, Wu G, Dong Z, Yuan S, Gu H
Cell death & disease 2025 Jan 20;16(1):30
Cell death & disease 2025 Jan 20;16(1):30
Comprehensive Pan-Cancer Analysis and Functional Studies Reveal SLC2A6 as a Ferroptosis Modulator in Hepatocellular carcinoma.
Yan G, Huang H, Lu Z, Chen M, Wang X, Zhong P, Qin C, Mo S, Han C, Luo X, Ye X
Scientific reports 2025 Jan 20;15(1):2545
Scientific reports 2025 Jan 20;15(1):2545
Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma.
Wang H, Fan S, Zhan Y, Xu Y, Du Y, Luo J, Zang H, Peng S, Wang W
Cell death & disease 2025 Jan 16;16(1):21
Cell death & disease 2025 Jan 16;16(1):21
IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A.
Wang X, Yang Y, Zhou X, Yu S, Luo X, Lu L, Gao Z, Yang J
Cell death discovery 2025 Jan 16;11(1):9
Cell death discovery 2025 Jan 16;11(1):9
ZC3H13 may participate in the ferroptosis process of sepsis-induced cardiomyopathy by regulating the expression of Pnn and Rbm25.
Lin W, Li H, Chang J, Huang Y
Gene 2025 Jan 15;933:148944
Gene 2025 Jan 15;933:148944
Effects of pesticide dichlorvos on liver injury in rats and related toxicity mechanisms.
Zhang P, Zhou Z, Yao J, Jiang Y, Lei H, Xie Z, Li J, Zhao X, Zhu L, Wan M, Liu L, Tang W
Ecotoxicology and environmental safety 2025 Jan 15;290:117747
Ecotoxicology and environmental safety 2025 Jan 15;290:117747
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Yu FF, Zuo J, Wang M, Yu SY, Luo KT, Sha TT, Li Q, Dong ZC, Zhou GY, Zhang F, Guo X, Ba Y, Wang YJ
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Trehalose Inhibits ferroptosis Through Activating SIRT3/SOD2 Signaling Axis and Alleviates Brain Injury After Traumatic Brain Injury.
Mu Z, Sun Z, Wu S, Yang J, Wang P, Zhao X
Neurochemical research 2025 Jan 11;50(1):78
Neurochemical research 2025 Jan 11;50(1):78
CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis.
Wang A, Liu J, Li Z, Qian Z, Yang S, Luo S, Lin J, Wu J
Ecotoxicology and environmental safety 2025 Jan 1;289:117417
Ecotoxicology and environmental safety 2025 Jan 1;289:117417
Synthesis and anti-tumor activity of menthylamine derivatives: Focusing on the potent inhibitory effect of compound W8 on glioma growth.
Wu X, Zhuo Y, Liu J, He Z, Wang M, Lei W, Liang Q, Wang A, Shen Z, Chen S, Zheng S, Huang H
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Bioorganic & medicinal chemistry 2025 Jan 1;117:118024
Artemisinin inhibits neuronal ferroptosis in Alzheimer's disease models by targeting KEAP1.
Deng PX, Silva M, Yang N, Wang Q, Meng X, Ye KQ, Gao HC, Zheng WH
Acta pharmacologica Sinica 2025 Feb;46(2):326-337
Acta pharmacologica Sinica 2025 Feb;46(2):326-337
Platycodin D2 Mediates Incomplete Autophagy and Ferroptosis in Breast Cancer Cells by Regulating Mitochondrial ROS.
Li Y, Lin H, Sun Y, Zhao R, Liu Y, Han J, Zhu Y, Jin N, Li X, Zhu G, Li Y
Phytotherapy research : PTR 2025 Feb;39(2):581-592
Phytotherapy research : PTR 2025 Feb;39(2):581-592
EFNA4-enhanced deubiquitination of SLC7A11 inhibits ferroptosis in hepatocellular carcinoma.
Zhong X, Zhu Z, Du Y, Long L, Xie Z, Zhang Y, Yao H, Lin J, Chen F
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):349-363
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):349-363
Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis.
Chen C, Wang J, Cheng M, Xie H, Li W, Zhang C
Pharmacological research 2025 Feb;212:107587
Pharmacological research 2025 Feb;212:107587
Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1.
Xie B, Wu P, Liu H, Yang X, Huang L
Journal of translational medicine 2025 Feb 7;23(1):165
Journal of translational medicine 2025 Feb 7;23(1):165
Ferristatin II protects nucleus pulposus against degeneration through inhibiting ferroptosis and activating HIF-1α pathway mediated mitophagy.
Su C, Jing X, Liu X, Shao Y, Zheng Y, Liu X, Cui X
International immunopharmacology 2025 Feb 6;147:113895
International immunopharmacology 2025 Feb 6;147:113895
Hypoxia-Regulated CD44 and xCT Expression Contributes to Late Postoperative Epilepsy in Glioblastoma.
Kusakabe K, Inoue A, Ohnishi T, Nakamura Y, Ohtsuka Y, Nishikawa M, Yano H, Choudhury ME, Murata M, Matsumoto S, Suehiro S, Yamashita D, Shigekawa S, Watanabe H, Kunieda T
Biomedicines 2025 Feb 5;13(2)
Biomedicines 2025 Feb 5;13(2)
O-GlcNAcylation of DJ-1 suppresses ferroptosis in renal cell carcinoma by affecting the transsulfuration pathway.
Yan Z, Li Y, Wang M, Xu K, Liu Y, Wang L, Luo H, Chen Z, Liu X
International immunopharmacology 2025 Feb 20;148:114098
International immunopharmacology 2025 Feb 20;148:114098
Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis.
Shen X, Chen Y, Tang Y, Lu P, Liu M, Mao T, Weng Y, Yu F, Liu Y, Tang Y, Wang L, Niu N, Xue J
Cell reports. Medicine 2025 Feb 18;6(2):101928
Cell reports. Medicine 2025 Feb 18;6(2):101928
GLS1-mediated glutamine metabolism mitigates oxidative stress-induced matrix degradation, ferroptosis, and senescence in nucleus pulposus cells by modulating Fe(2+) homeostasis.
Wu J, Qin T, Han W, Zhang C, Zhang X, Huang Z, Wu Y, Xu Y, Xu K, Ye W
Free radical biology & medicine 2025 Feb 16;228:93-107
Free radical biology & medicine 2025 Feb 16;228:93-107
Lactate-Fueled Theranostic Nanoplatforms for Enhanced MRI-Guided Ferroptosis Synergistic with Immunotherapy of Hepatocellular Carcinoma.
Chen X, Zhang F, Lu C, Wu R, Yang B, Liao T, Du B, Wu F, Ding J, Fang S, Zhao Z, Chen M, Shu G, Chen W, Ji J
ACS applied materials & interfaces 2025 Feb 12;17(6):9155-9172
ACS applied materials & interfaces 2025 Feb 12;17(6):9155-9172
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Zhang L, Zheng G, Zhao W, He C, Huang Z
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4-mediated ferritinophagy.
Fu Y, Huang G, Cai Y, Ren M, Cheng R, Chai Y, Wang Y, An Y, Yan T, Zhu L, Liu X
Chemico-biological interactions 2025 Feb 1;407:111368
Chemico-biological interactions 2025 Feb 1;407:111368
Puerarin reduces susceptibility to ventricular arrhythmias and inhibits ferroptosis via Sirt1/Nrf2 signaling in high-fat-diet rats.
Jiang S, Qiu S, Mu Y, Liu C, Han Y, Jiang J, Wang Y
Free radical biology & medicine 2025 Feb 1;227:472-484
Free radical biology & medicine 2025 Feb 1;227:472-484
Ferroptosis suppressor protein 1 regulated oligodendrocytes ferroptosis rescued by idebenone in spinal cord injury.
Fan B, Liu D, Qin J, Shi Z, Hu Z, Gao X, Ren Y, Zhao P, Chen X, Ren Y, Ning G, Liu T, Feng S
Free radical biology & medicine 2025 Feb 1;227:129-142
Free radical biology & medicine 2025 Feb 1;227:129-142
ZBTB20 promotes ferroptosis through inhibiting TMEM109 expression in glioblastoma cells.
Chen X, Luo M, Niu X, Wang W, Cao H, Zhang L, Wei R, Duan P
International journal of oncology 2025 Dec;67(6)
International journal of oncology 2025 Dec;67(6)
Targeting SLC7 A11 Ameliorates Ulcerative Colitis by Promoting Efferocytosis Through the ERK1/2 Pathway.
You M, Li J, Wang X, Liu Y, Chen S, Wang P
Inflammation 2025 Dec;48(6):4080-4093
Inflammation 2025 Dec;48(6):4080-4093
Maresin-1 alleviates sepsis-induced acute kidney injury by inhibiting ferroptosis via the Nrf2/HO-1/Gpx4 signaling pathway.
Tang L, He D, Wan P, Gou X, Wang Y, Li X
Renal failure 2025 Dec;47(1):2575112
Renal failure 2025 Dec;47(1):2575112
4-Methoxylonchocarpin protects against cisplatin induced acute kidney injury via regulating ferroptosis.
Jiao N, Wang B, Zhang Q, Liu Y, Zhao F
Renal failure 2025 Dec;47(1):2545941
Renal failure 2025 Dec;47(1):2545941
Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production.
Tian Y, Zhou C, Yan Q, Li Z, Chen D, Feng B, Song J
Renal failure 2025 Dec;47(1):2438857
Renal failure 2025 Dec;47(1):2438857
Network pharmacology combined with experiments to explore the molecular mechanism of Jiawei Erzhi pill protects against atherosclerosis by inhibiting ferroptosis.
Guiping MA, Ran C, Junlong LI, Le S, Shiping HU, Yiyi Z, Chuangxiong H
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Dec;45(6):1330-1341
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2025 Dec;45(6):1330-1341
Development and Validation of a New Prediction Criteria for Neoadjuvant Chemotherapy Response in Locally Advanced Gastric Cancer Based on Ferroptosis-Related Biomarkers.
Shen M, Cai Q, Wang R, Zhang F, Chen H, Wang X, Xie R, Zhang J, Liu B, He Y, Hou X, Yang D
Journal of gastroenterology and hepatology 2025 Dec;40(12):2913-2924
Journal of gastroenterology and hepatology 2025 Dec;40(12):2913-2924
Lactoferrin-cyanidin-3-glucoside nanoparticles alleviate inflammation and oxidative stress via Sesn2/Nrf2 activation in mastitis.
Amona FM, Pang Y, Chen X, Liu Z, Su C, Yang J, Liu K, Wu Q, Liu B, Chen X, Zhang C
Materials today. Bio 2025 Dec;35:102491
Materials today. Bio 2025 Dec;35:102491
Injectable magnetic hydrogel induces multi-programmed cell death and deep tumor regression in magnetic hyperthermia therapy in hepatocellular carcinoma.
Zhang L, He X, Zhu H, Sun Q, Liu Y, Huang L, Wen T, Li J, Lan Z, Yu Z, Yang Z, Jia K, Sun K, Wang Z
Materials today. Bio 2025 Dec;35:102341
Materials today. Bio 2025 Dec;35:102341
Integrated transcriptome profiling and in vitro analysis reveals MLN4924's role in inducing ferroptosis in acute myeloid leukemia.
Jian J, Guo Y, Tang X, Zhao L, Liu B
Hematology (Amsterdam, Netherlands) 2025 Dec;30(1):2497041
Hematology (Amsterdam, Netherlands) 2025 Dec;30(1):2497041
FXR/SMAD3 Regulates SOX9 to Inhibit Hepatic Fibrosis in Biliary Atresia via Inhibiting Ferroptosis of Hepatic Stellate Cells.
Xi Z, Kong L, Zhang Y, He W, Ma P, Zhen J, Yan P
Applied biochemistry and biotechnology 2025 Dec;197(12):7946-7959
Applied biochemistry and biotechnology 2025 Dec;197(12):7946-7959
Astaxanthin suppress ferroptosis through the Akt1-FoxO3a signaling pathway to alleviates brain injury after intracerebral hemorrhage.
Zhang J, Hua Q, Gao L, Yang S, Lu M, Cai Q
Journal of pharmacological sciences 2025 Dec;159(4):310-321
Journal of pharmacological sciences 2025 Dec;159(4):310-321
HOXA13 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating SLC7A11 and SLC3A2.
Ma Y, Liu R, Qi P, Wei S, Ren Z, Zhang A, Fan B
Cellular signalling 2025 Dec;136:112168
Cellular signalling 2025 Dec;136:112168
Melatonin attenuates lipopolysaccharide-induced acute myocardial injury by regulating KLF4 expression.
Dan Z, Liu W, Zhang H, Shi X, Zhu R, Yang M, Wang Y, Zhu H
Cellular signalling 2025 Dec;136:112080
Cellular signalling 2025 Dec;136:112080
CBX2 and EZH2 cooperatively contribute to 5-Fu resistance in gastric cancer by suppressing ferroptosis via trimethylation of H3k27.
Zeng M, Li B, Guan Q, Cai H
Cellular signalling 2025 Dec;136:112078
Cellular signalling 2025 Dec;136:112078
Inhibition of EgRad50 leads to impaired DNA repair in Echinococcus granulosus sensu stricto.
Zhao J, Xu S, Du Y, Tuniyazi X, Li J, Liao X, Jia Y, Lü G, Zhao J
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2025 Dec;136:105855
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2025 Dec;136:105855
Dauricine Inhibits Macrophages M2 Polarization and Regulates the Progression and Ferroptosis via HCK/IDO1 in Urinary Bladder Cancer.
Gong J, Sun D, Zheng Y, Mao C, Yu B, Li X, Xuan Y
Food science & nutrition 2025 Dec;13(12):e71341
Food science & nutrition 2025 Dec;13(12):e71341
Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway.
Zhen Q, Xu Y, Xu Y, Liu X, Zhang Y, Ye D, Han S, Liu S, Zhang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e12599
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e12599
Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress-Related Male Reproductive Dysfunction.
Zhang L, Gao S, Xiong X, Liu X, Li R, Wang X, Han L, Xiao X, Wang X, Li W, Chang Y, Du Y, Yang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e04817
MiR-122-5p modulates ferroptosis via SLC7A11: A potential therapeutic target in autoimmune hepatitis.
Suo Y, Wang Y, Su Y, Wang Q, Jia J, Zhao X
Journal of translational autoimmunity 2025 Dec;11:100303
Journal of translational autoimmunity 2025 Dec;11:100303
Echinacoside as a Novel Ferroptosis Inducer in Hepatocellular Carcinoma: Mechanistic Insights from TP53/SLC7A11/GPX4 Pathway Modulation.
Wang P, Lin J, Su D
International journal of molecular sciences 2025 Dec 30;27(1)
International journal of molecular sciences 2025 Dec 30;27(1)
Super-enhancers mediates SLC7A11 via FOXA1 to regulate disulfidptosis in prostate cancer.
Kang Z, Lin B, Ke ZB, Zheng QS, Xue XY, Wei Y, Xu N
Cell death & disease 2025 Dec 3;17(1):63
Cell death & disease 2025 Dec 3;17(1):63
Cytochrome c Oxidase Subunit COX4-1 Reprograms Erastin-Induced Cell Death from Ferroptosis to Apoptosis: A Transmitochondrial Study.
Oliva CR, Flor S, Griguer CE
Antioxidants (Basel, Switzerland) 2025 Dec 28;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 28;15(1)
Tip60-HDAC8-SMURF2-mediated β-TrCP1 degradation is a key mechanism for hypoxia-induced cell death and tissue injury.
Li S, Zhang BW, Wei ZJ, Xi Y, Zhang GA, Zhang Y, Kou DC, Song XP, Huang J, Song P, Liang KY, Pei SS, Feng HY, Li SP, Lou QQ, Liu Y, Yao KH, Yang L, Chen S
Cellular and molecular life sciences : CMLS 2025 Dec 27;83(1):43
Cellular and molecular life sciences : CMLS 2025 Dec 27;83(1):43
NEDD4 suppresses ferroptosis in lung ischemia-reperfusion injury by ubiquitinating and degrading SLC1A5.
Li J, Meng F, Qian X, Chen S
Scientific reports 2025 Dec 23;16(1):2568
Scientific reports 2025 Dec 23;16(1):2568
Ferroptosis inhibition via the ROS-GPX4 axis drives microplastic-induced malignant progression of nasopharyngeal carcinoma.
Deng X, Liu X, Feng J, Zhao L
Journal of translational medicine 2025 Dec 22;24(1):210
Journal of translational medicine 2025 Dec 22;24(1):210
Targeting intrinsically disordered nuclear protein 1 (NUPR1) with single-domain antibodies alleviates triple-negative breast cancer (TNBC) progression in vivo.
Wang T, Wang M, Chen X, Yin Y, Xu J, Sun Y, Wu A, Liu Z, Ma Z
Cell death & disease 2025 Dec 22;16(1):913
Cell death & disease 2025 Dec 22;16(1):913
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
Sun Y, Wang J, Gu D, Lou H, Sun J, Cui Z, Kang W
Cell death & disease 2025 Dec 18;17(1):101
Cell death & disease 2025 Dec 18;17(1):101
Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC.
Yang X, Wu Y, Zhang Q, Zhou Y, Chang S, Zhang C, Liu D
BMC cancer 2025 Dec 13;26(1):81
BMC cancer 2025 Dec 13;26(1):81
Auranofin facilitates gemcitabine sensitivity by regulating TXNRD1-related ferroptosis in pancreatic ductal adenocarcinoma.
Lu SY, Fang DL, Zhao ZY, Zhu YQ, Liu ZD, Ma MJ, Ye JY, Xu QC, Yin XY
Cancer letters 2025 Dec 1;634:218058
Cancer letters 2025 Dec 1;634:218058
RBMS2 mediates SLC7A11 transcription-translation to regulate ferroptosis in colorectal cancer.
Wang X, Liu P, An Y, Hu Y, Qiao H, Miao H
Free radical biology & medicine 2025 Dec 1;240:504-513
Free radical biology & medicine 2025 Dec 1;240:504-513
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Wang Y, Zhao Y, Zhao W, Chen H, Cao Z, Li H, Tang Y, Zhu X, Yao P
Free radical biology & medicine 2025 Dec 1;240:238-252
Free radical biology & medicine 2025 Dec 1;240:238-252
Nrg4 Secreted by Brown Adipose Tissue Suppresses Ferroptosis of Sepsis-Induced Liver Injury.
Feng L, Cui J, Chen W, Zhu L, Li P, Zhou H, Sun Y, Yi W
Inflammation 2025 Aug;48(4):2783-2801
Inflammation 2025 Aug;48(4):2783-2801
PRMT5 K240lac confers ferroptosis resistance via ALKBH5/SLC7A11 axis in colorectal cancer.
Qu S, Feng B, Xing M, Qiu Y, Ma L, Yang Z, Ji Y, Huang F, Wang Y, Zhou J, Xu M, He J, Zhou Q, Zhou X, Xiong W, Yao B, Liu M, Dong Q, Yang L, Gu S
Oncogene 2025 Aug;44(32):2814-2830
Oncogene 2025 Aug;44(32):2814-2830
SETD5 facilitates stemness and represses ferroptosis via m6A-mediating PKM2 stabilization in non-small cell lung cancer.
Liu X, Cui Y, Gong J, Yu X, Cui Y, Xuan Y
Oncogene 2025 Aug;44(29):2474-2489
Oncogene 2025 Aug;44(29):2474-2489
METTL3 increases ferroptosis resistance to facilitate the tumor-like features of rheumatoid arthritis synovial fibroblasts through enhancing SLC7A11 mRNA stability in an m6A-IGF2BP2-dependent manner.
Xu Y, Liu W, Zai Z, Qian X, Hu W, Peng X, Chen F
International journal of biological macromolecules 2025 Aug;320(Pt 1):145698
International journal of biological macromolecules 2025 Aug;320(Pt 1):145698
A novel FTO-targeting nanodrug induces disulfidptosis and ameliorates the suppressive tumor immune environment to treat uveal melanoma.
Tian H, Deng H, Liu X, Liu C, Zhang C, Leong KW, Fan X, Ruan J
Biomaterials 2025 Aug;319:123168
Biomaterials 2025 Aug;319:123168
A ROS-mediated oxidation-O-GlcNAcylation cascade governs ferroptosis.
Zhang H, Ma J, Hou C, Luo X, Zhu S, Peng Y, Peng C, Li P, Meng H, Xia Y, Jiang Z, Modepalli S, Duttargi A, Kupfer GM, Cai M, Zhang H, Ma J, Li J, Han S, Pei H
Nature cell biology 2025 Aug;27(8):1288-1300
Nature cell biology 2025 Aug;27(8):1288-1300
Salinomycin inhibits SREBP1 to sensitize ferroptosis and ameliorate sorafenib resistance in clear cell renal cell carcinoma.
Su Y, Liu X, Wang D, Li G, Mi X, Zhang Y, Yue S, Zhang Z, Shen T, Tan X
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119989
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119989
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
Li Y, Jiang J, Zhuo Y, Li J, Li Y, Xia Y, Yu Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Liang Z, Liu J, Gou Y, Wang H, Li Z, Cao Y, Zhang H, Bai R, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells.
Lei M, Liu B, Wan B, Feng Y, Teng Y, Xi D, Zeng G, Zong S
European journal of medical research 2025 Aug 5;30(1):713
European journal of medical research 2025 Aug 5;30(1):713
WTAP Dysregulation Mediates HLF-m6A Modification to Inhibit Trophoblast Ferroptosis in Preeclampsia.
Liu S, Zhang L, Li Y, Jia X, Kang J, Sun M, Zhang X, Tang J, Meng T
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70961
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 31;39(16):e70961
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
Zhang L, Chen W, Huang W, Cheng H
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
Erchen decoction alleviates silicosis by attenuating ferroptosis and fibrosis in alveolar macrophages via modulating the P53/HMOX1 pathway.
Wang Z, Lu J, Liu C, Liang X, Zeng P, Lu F
Journal of ethnopharmacology 2025 Aug 29;352:120227
Journal of ethnopharmacology 2025 Aug 29;352:120227
Bu-Yang decoction attenuates OVX-induced sarcopenia by upregulating CXCR4 to suppress GPX4-mediated ferroptosis.
Xie Z, Xu P, Xie J, Ma T, Wang W, Yang Y, Sheng C, Wang J, Wu M, Zhou X, Liu J, Zhou X, Tong P, Xia H
Journal of ethnopharmacology 2025 Aug 29;352:120166
Journal of ethnopharmacology 2025 Aug 29;352:120166
ERBB3 influences the ferroptosis pathway via modulation of lipid peroxidation and GSH synthesis in gastric cancer.
Jenke R, Heinrich T, Lordick F, Aigner A
Cell death discovery 2025 Aug 22;11(1):398
Cell death discovery 2025 Aug 22;11(1):398
A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma.
Li J, Ma C, Cao P, Guo W, Wang P, Yang Y, Ding B, Yin F, Li Z, Wang Y, Li S, Huang C, Wang X, Zhou T, Chang A, Zhao L, Gao S, Zhao T, Wang H, Yu J, Xu J, Feng Y, Hao J
Cell reports. Medicine 2025 Aug 19;6(8):102292
Cell reports. Medicine 2025 Aug 19;6(8):102292
Sulfasalazine induces ferroptosis in osteosarcomas by regulating Nrf2/SLC7A11/GPX4 signaling axis.
Qin Q, Zhang H, Lai M, Wei J, Qian J, Chen X, Wang X, Wang Y
Scientific reports 2025 Aug 18;15(1):30197
Scientific reports 2025 Aug 18;15(1):30197
Synthesis of USP5-IN-1 derivatives as novel USP5 inhibitors with potent activity against cholangiocarcinoma cells.
Hu X, Yu Z, Zhu H, Cui H, Ning F, Dai J, Zhang J, Li Y, Zhang X
Bioorganic & medicinal chemistry 2025 Aug 15;126:118213
Bioorganic & medicinal chemistry 2025 Aug 15;126:118213
Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection.
Yang M, Yu Z, Ping J, Duan Y, Tang J, Liu W, He Q, Lai Y, Lam SM, Tang H, Liu Z, Wang W, Zhu M, Hu W, Han Y, Shui G, Hao J, Liu Z, Wu N
Science advances 2025 Aug 15;11(33):eadx6587
Science advances 2025 Aug 15;11(33):eadx6587
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Zhang E, Wang Y, Zhang H, Li X, Su Y, Cui J, Xu R, Mao X, Sang M, Lin Z, Zhou X
Free radical biology & medicine 2025 Aug 1;235:231-247
Free radical biology & medicine 2025 Aug 1;235:231-247
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Deng W, Zhao J, Wang X, Li D, Wang M, Zheng X, Wang R, Guo Q, Zhao P, Yan H, Shen L, Long C, Wei G, Wu S
Free radical biology & medicine 2025 Aug 1;235:150-161
Free radical biology & medicine 2025 Aug 1;235:150-161
Key role of the CSE/transsulfuration pathway in macrophage phenotypic change under iron overload.
Yuan Z, Chen Y, Xin Y, Zhang Y, Dong Z, Wang J, Wang X, Yang G, Li S
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Apr;88:127611
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Apr;88:127611
Decreased gut microbiome-derived indole-3-propionic acid mediates the exacerbation of myocardial ischemia/reperfusion injury following depression via the brain-gut-heart axis.
Mu X, Feng L, Wang Q, Li H, Zhou H, Yi W, Sun Y
Redox biology 2025 Apr;81:103580
Redox biology 2025 Apr;81:103580
Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux.
Zhang H, Shi H, Li X, Zhou S, Song X, Ma N, Meng M, Chang G, Shen X
Redox biology 2025 Apr;81:103557
Redox biology 2025 Apr;81:103557
Generation of Myeloid-Specific Bmal1 Knockout Mice and Identification of Bmal1-Regulated Ferroptosis in Macrophages.
Chen Q, Wang W, Fang W, Qin L, Wang J, Huang X, Pan S, Zheng R
Genesis (New York, N.Y. : 2000) 2025 Apr;63(2):e70014
Genesis (New York, N.Y. : 2000) 2025 Apr;63(2):e70014
Regulatory factor X1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by transcriptional regulation of BECN1.
Yang Z, Yuan Y, Niu Y, Zuo D, Liu W, Li K, Shi Y, Qiu Z, Li K, Lin Z, Zhong C, Huang Z, He W, Guan X, Yuan Y, Zeng W, Qiu J, Li B
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):505-522
Cellular oncology (Dordrecht, Netherlands) 2025 Apr;48(2):505-522
Nrf2 alleviates acute ischemic stroke induced ferroptosis via regulating xCT/GPX4 pathway.
Ye Y, Xie X, Bi Y, Liu Q, Qiu L, Zhao H, Wang C, Zhu W, Zeng T
Free radical biology & medicine 2025 Apr;231:153-162
Free radical biology & medicine 2025 Apr;231:153-162
β-Diketone Functionalized Microspheres Chelate Reactive Iron via Metal Coordination for Cartilage Repair.
Xu Y, Gu X, Li X, Chen Y, Wei Z, Wang J, Liu Y, Ji Y, Cheng Q, Jiang S, Yu J, Li X, Cui W, Ye X
Advanced healthcare materials 2025 Apr;14(10):e2403933
Advanced healthcare materials 2025 Apr;14(10):e2403933
Yinaoxin granule alleviates cerebral ischemia-reperfusion injury by ferroptosis inhibition through Nrf2 pathway activation.
Weng J, Liu L, Li S, Yang Y, Zhou R, Zhang Z, Liu Y, Chen L, Feng Z, Tang Z, Xu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156476
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156476
Mechanistic study of METTL3 inducing ferroptosis to promote cervical cancer progression through mediating m6A modification of COTE-1.
Min L, Huo F, Zhu Z, Din L, Zhang L, Xu Y, Xing X, Zhang P, Wang Q
Cellular signalling 2025 Apr;128:111649
Cellular signalling 2025 Apr;128:111649
Dapagliflozin alleviates high-fat-induced obesity cardiomyopathy by inhibiting ferroptosis.
Chen D, Shi J, Wu Y, Miao L, Wang Z, Wang Y, Xu S, Lou Y
ESC heart failure 2025 Apr;12(2):1358-1373
ESC heart failure 2025 Apr;12(2):1358-1373
MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non-Small Cell Lung Cancer.
Zhang F, Huang B, Xu Y, Cao G, Shen M, Liu C, Luo J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2415814
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(16):e2415814
Short-term effects of subacute ruminal acidosis on ferroptosis and iron metabolism in the livers of lactating sheep fed a high-grain diet.
Zhang H, Shi H, Zhou S, Meng M, Ma N, Chang G, Shen X
Journal of dairy science 2025 Apr;108(4):4365-4380
Journal of dairy science 2025 Apr;108(4):4365-4380
Tanshinone IIA Ameliorates Myocardial Ischemia-Reperfusion Injury via Activating HDAC1-Repressed Nrf2-xCT/Gpx4/HO-1 Axis.
Yan K, Yu S, Gao X, Li L, Ding L
Chemical biology & drug design 2025 Apr;105(4):e70095
Chemical biology & drug design 2025 Apr;105(4):e70095
The long noncoding RNA APR attenuates PPRV infection-induced accumulation of intracellular iron to inhibit membrane lipid peroxidation and viral replication.
Wen B, Chang W, Yang L, Lv D, Wang L, Wang L, Xu Y, Hu J, Ding K, Xue Q, Qi X, Yang B, Wang J
mBio 2025 Apr 9;16(4):e0012725
mBio 2025 Apr 9;16(4):e0012725
Mechanism of Mitophagy to Protect Yak Kidney from Hypoxia-Induced Fibrosis Damage by Regulating Ferroptosis Pathway.
Bai X, Lu H, Ma R, Yu S, Yang S, He J, Cui Y
Biomolecules 2025 Apr 9;15(4)
Biomolecules 2025 Apr 9;15(4)
Pharmacological targeting of the mitochondrial phosphatase PTPMT1 sensitizes hepatocellular carcinoma to ferroptosis.
Li M, Wang Y, Li X, Xu J, Yan L, Tang S, Liu C, Shi M, Liu R, Zhao Y, Zhang Y, Yang L, Zhang Y, Wang G, Li Z, Guo Y, Feng Y, Liu P
Cell death & disease 2025 Apr 6;16(1):257
Cell death & disease 2025 Apr 6;16(1):257
Identification of HCAR1 as a ferroptosis-related biomarker of gastric cancer based on a novel ferroptosis-related prognostic model and in vitro experiments.
Zhang H, Zhan J, Zhou J, Liu L, He Y, Le Y, Liu W, Zhou L, Liu Y, Xiang X
Carcinogenesis 2025 Apr 3;46(2)
Carcinogenesis 2025 Apr 3;46(2)
TAZ/NRF2 positive feedback loop contributes to proliferation in bladder cancer through antagonistic ferroptosis.
Song Z, Gui S, Rao X, Zhang G, Cheng Y, Zeng T
Cell death discovery 2025 Apr 29;11(1):208
Cell death discovery 2025 Apr 29;11(1):208
Vaccarin alleviates renal ischemia-reperfusion injury by inhibiting inflammation and ferroptosis.
Fan Q, Liu D, Chu C, Wang Y, Liu M, Liu Y, Huang Y, Zhang J, Wen J
International immunopharmacology 2025 Apr 24;153:114463
International immunopharmacology 2025 Apr 24;153:114463
Saponins from Astragalus membranaceus (Fisch.) Bge Alleviated Neuronal Ferroptosis in Alzheimer's Disease by Regulating the NOX4/Nrf2 Signaling Pathway.
Wang M, Li M, Jiang Y, Wang S, Yang X, Naseem A, Algradi AM, Hao Z, Guan W, Chen Q, Zhang L, Kuang H, Yang B, Liu Y
Journal of agricultural and food chemistry 2025 Apr 2;73(13):7725-7740
Journal of agricultural and food chemistry 2025 Apr 2;73(13):7725-7740
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
Zuo X, Wang X, Xie J, Jia Y
International ophthalmology 2025 Apr 2;45(1):141
International ophthalmology 2025 Apr 2;45(1):141
RNF128 promotes gastric cancer progression by inhibiting autophagy-dependent ferroptosis through Beclin1 ubiquitination.
Zhu Z, Chen Q, Song S, Peng S, Ding H, Li B, Liu C, Jin X, Li L, Zhu J, Zhang G
Cell death discovery 2025 Apr 19;11(1):187
Cell death discovery 2025 Apr 19;11(1):187
FADS2 inhibits colorectal cancer cell proliferation by regulating ferroptosis through SLC7A11/GPX4.
Yang Q, Zhang H, Luo J, Yu H, Yang X, Wang C
Molecular biology reports 2025 Apr 15;52(1):394
Molecular biology reports 2025 Apr 15;52(1):394
Artesunate induces ferroptosis in osteosarcoma through NCOA4-mediated ferritinophagy.
Huang R, Xu R, Shi J, Yang Z, Zheng J, Wei D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70488
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70488
TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer.
Huang C, Zeng Q, Chen J, Wen Q, Jin W, Dai X, Ruan R, Zhong H, Xia Y, Wu Z, Huang R, Zhang J, Yao Y, Li L, Lei W, Xiong J, Deng J
Cell death & disease 2025 Apr 13;16(1):287
Cell death & disease 2025 Apr 13;16(1):287
CircMFN2/miR-361-3p/ELK1 feedback loop promotes glutaminolysis and the progression of hepatocellular carcinoma.
Hao X, Qian X, Xie C, Wang Z, Wang X, Ji Y, Zhang X, Li Q, Wan B, Cui H, Wang L, Yang N, Qiao L, Yu H, Han F, Zhuang H, Zhou J
Cancer letters 2025 Apr 1;614:217473
Cancer letters 2025 Apr 1;614:217473
Protocadherin 17 weakens the lenvatinib resistance of liver cancer through inducing ferroptosis.
Yang J, Hu B, Zhang G, Wu K, Zhang X, Ji M, Zhang B, Shi H, Li D
Experimental cell research 2025 Apr 1;447(1):114495
Experimental cell research 2025 Apr 1;447(1):114495
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M
Nature communications 2025 Apr 1;16(1):3131
Nature communications 2025 Apr 1;16(1):3131
Cell Cycle-Related Centromere Protein F Deficiency Suppresses Ovarian Cancer Cell Growth by Inducing Ferroptosis.
Liu X, Guo L, Suo Y, Tang X, Zhu T, Zhao T, Zhang W, Zhang P
Gynecologic and obstetric investigation 2024;89(5):424-436
Gynecologic and obstetric investigation 2024;89(5):424-436
Triptolide Attenuates Renal Slit Diagram to Tight Junction Transition in Diabetic Kidney Disease by Regulating Nrf2-Ferroptosis Pathway.
Wang HQ, Wu HX, Shi WQ, Yang Y, Lin M, Wang K, Bian CC, An XF, Wang T, Yan M
The American journal of Chinese medicine 2024;52(7):2161-2185
The American journal of Chinese medicine 2024;52(7):2161-2185
Aberrant Expression of SLC7A11 Impairs the Antimicrobial Activities of Macrophages in Staphylococcus Aureus Osteomyelitis in Mice.
Yang B, Shu W, Hu J, Wang Z, Wu J, Su J, Tan J, Yu B, Zhang X
International journal of biological sciences 2024;20(7):2555-2575
International journal of biological sciences 2024;20(7):2555-2575
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis.
Wang H, Zhao W, Wang D, Chen J
Open medicine (Warsaw, Poland) 2024;19(1):20240941
Open medicine (Warsaw, Poland) 2024;19(1):20240941
Systematic Pharmacology and Experimental Validation to Reveal the Alleviation of Astragalus membranaceus Regulating Ferroptosis in Osteoarthritis.
Chen K, Yu Y, Wang Y, Zhu Y, Qin C, Xu J, Zou X, Tao T, Li Y, Jiang Y
Drug design, development and therapy 2024;18:259-275
Drug design, development and therapy 2024;18:259-275
Cardamonin Attenuates Myocardial Ischemia/Reperfusion-Induced Ferroptosis Through Promoting STAT3 Signaling.
Yang T, Wu P, Jiang L, Chen R, Jin Q, Ye G
Journal of inflammation research 2024;17:8861-8879
Journal of inflammation research 2024;17:8861-8879
Gandouling Regulates Ferroptosis and Improves Neuroinflammation in Wilson's Disease Through the LCN2/NLRP3 Signaling Pathway.
Wen Y, Zhao C, Chen J, Tian L, Wu B, Xie W, Dong T
Journal of inflammation research 2024;17:5599-5618
Journal of inflammation research 2024;17:5599-5618
The High Expression of SLC7A11 and GPX4 are Significantly Correlated with β-Catenin in Colorectal Cancer.
Ou Y, Wu N, Shu L, Zhao Y, Bao Y, Wu Q
Cancer management and research 2024;16:1639-1648
Cancer management and research 2024;16:1639-1648
miR-141-3p promotes paclitaxel resistance by attenuating ferroptosis via the Keap1-Nrf2 signaling pathway in breast cancer.
Duan WL, Wang XJ, Guo A, Gu LH, Sheng ZM, Luo H, Yang LX, Wang WH, Zhang BG
Journal of Cancer 2024;15(17):5622-5635
Journal of Cancer 2024;15(17):5622-5635
NCAPD3-mediated ferroptosis of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside inhibits proliferation in T47D cells.
Shen J, Zhang S, Song Y, Yang L, Huang Q, Wang P, Zhang Y
Frontiers in pharmacology 2024;15:1531220
Frontiers in pharmacology 2024;15:1531220
Dissecting the functions and regulatory mechanisms of disulfidoptosis-related RPN1 in pan-cancer: modulation of immune microenvironment and cellular senescence.
Qin L, Liang T, Zhang H, Gong X, Wei M, Song X, Hu Y, Zhu X, Hu W, Li J, Wang J
Frontiers in immunology 2024;15:1512445
Frontiers in immunology 2024;15:1512445
Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis.
Huang R, Chu D, Shi J, Xu R, Wang K
Frontiers in pharmacology 2024;15:1490759
Frontiers in pharmacology 2024;15:1490759
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
Li P, Li D, Lu Y, Pan S, Cheng F, Li S, Zhang X, Huo J, Liu D, Liu Z
Frontiers in immunology 2024;15:1457230
Frontiers in immunology 2024;15:1457230
Hydrogen sulfide protects against toxicant acrolein-induced ferroptotic cell death in Sertoli cells.
Mao Z, Ji Q, Chen P, Zhong K, Zeng X
Frontiers in pharmacology 2024;15:1440147
Frontiers in pharmacology 2024;15:1440147
Multidimensional role of adapalene in regulating cell death in multiple myeloma.
Cao X, Xiang J, Zhang Q, Liu J, Zhou D, Xu Y, Xu P, Chen B, Bai H
Frontiers in pharmacology 2024;15:1415224
Frontiers in pharmacology 2024;15:1415224
LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway.
Deng Q, Gao Y, Wang Y, Mao J, Yan Y, Yang Z, Cong Y, Yang Y, Wan S
Frontiers in pharmacology 2024;15:1411513
Frontiers in pharmacology 2024;15:1411513
Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis.
Xie J, Liang X, Xie F, Huang C, Lin Z, Xie S, Yang F, Zheng F, Geng L, Xu W, Gong S, Xiang L
Frontiers in pharmacology 2024;15:1409001
Frontiers in pharmacology 2024;15:1409001
Exosomal miR-223-3p from bone marrow mesenchymal stem cells targets HDAC2 to downregulate STAT3 phosphorylation to alleviate HBx-induced ferroptosis in podocytes.
Chen Y, Yang X, Feng M, Yu Y, Hu Y, Jiang W
Frontiers in pharmacology 2024;15:1327149
Frontiers in pharmacology 2024;15:1327149
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer.
Zhu Y, Fang S, Fan B, Xu K, Xu L, Wang L, Zhu L, Chen C, Wu R, Ni J, Wang J
Theranostics 2024;14(4):1683-1700
Theranostics 2024;14(4):1683-1700
EIF4A3-induced circ_0022382 promotes breast cancer cell progression through the let-7a-5p/PI3K/AKT/mTOR signaling pathway and SLC7A11 axis.
Liu W, Zhang J, Zhang J, Ye Y, Zhu J, Yu Q, Li T, Sun X, Chen H
Frontiers in oncology 2024;14:1476731
Frontiers in oncology 2024;14:1476731
Comprehensive analysis of disulfidptosis-related genes and the immune microenvironment in heart failure.
Zhao L, Zhang J, Song Q, Dai C, Qin Y, Li A
Frontiers in cell and developmental biology 2024;12:1516898
Frontiers in cell and developmental biology 2024;12:1516898
Unveiling the mechanism of photothermal therapy in acne man-agement: targeting sebaceous gland ferroptosis via umbilical cord mesenchymal stem cell membrane-encapsulated Au-Ag-PDA.
Wu R, Li J, Tian H, Song D, Zhao T, Tian Y, Zouboulis CC, Jiang J, Zhu M
Frontiers in bioengineering and biotechnology 2024;12:1426477
Frontiers in bioengineering and biotechnology 2024;12:1426477
RAB17 promotes endometrial cancer progression by inhibiting TFRC-dependent ferroptosis.
Zhou X, Nie M, Xin X, Hua T, Zhang J, Shi R, Dong K, Shu W, Yan B, Wang H
Cell death & disease 2024 Sep 6;15(9):655
Cell death & disease 2024 Sep 6;15(9):655
Aldo-Keto reductase 1C3 reduces myocardial cell damage after acute myocardial infarction by activating the Kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2-antioxidant response element pathway to inhibit ferroptosis.
Miao W, Hu YZ
Journal of geriatric cardiology : JGC 2024 Sep 28;21(9):899-912
Journal of geriatric cardiology : JGC 2024 Sep 28;21(9):899-912
Ursolic Acid Ameliorates Alcoholic Liver Injury through Attenuating Oxidative Stress-Mediated Ferroptosis and Modulating Gut Microbiota.
Zhou L, Xiao M, Li Y, Chitrakar B, Sheng Q, Zhao W
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21181-21192
Journal of agricultural and food chemistry 2024 Sep 25;72(38):21181-21192
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway.
Ren X, Wen Y, Yuan M, Li C, Zhang J, Li S, Zhang X, Wang L, Wang S
European journal of pharmacology 2024 Sep 15;979:176820
European journal of pharmacology 2024 Sep 15;979:176820
Oxidative stress induces ferroptosis in tendon stem cells by regulating mitophagy through cGAS-STING pathway.
Gao Y, Sun W, Wang J, Zhao D, Tian H, Qiu Y, Ji S, Wang S, Fu Q, Zhang F, Zhang Z, Wang F, Shao J, Zheng S, Meng J
International immunopharmacology 2024 Sep 10;138:112652
International immunopharmacology 2024 Sep 10;138:112652
Downregulation of the (pro)renin receptor alleviates ferroptosis-associated cardiac pathological changes via the NCOA 4-mediated ferritinophagy pathway in diabetic cardiomyopathy.
Zhang X, Dong X, Jie H, Li S, Li H, Su Y, Li L, Kang L, Dong B, Zhang Y
International immunopharmacology 2024 Sep 10;138:112605
International immunopharmacology 2024 Sep 10;138:112605
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis.
Chen W, Han L, Yang R, Wang H, Yao S, Deng H, Liu S, Zhou Y, Shen XL
Archives of toxicology 2024 Oct;98(10):3323-3336
Archives of toxicology 2024 Oct;98(10):3323-3336
Borna disease virus 1 induces ferroptosis, contributing to lethal encephalitis.
Tan Q, Yang H, He Y, Shen X, Sun L, Du X, Lin G, Zhou N, Wang N, Zhou Q, Liu D, Xu X, Zhao L, Xie P
Journal of medical virology 2024 Oct;96(10):e29945
Journal of medical virology 2024 Oct;96(10):e29945
Targeting GPX4-mediated ferroptosis protection sensitizes BRCA1-deficient cancer cells to PARP inhibitors.
Xie X, Chen C, Wang C, Guo Y, Sun B, Tian J, Yan J, Li D, Chen G
Redox biology 2024 Oct;76:103350
Redox biology 2024 Oct;76:103350
Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response.
Sanz-Alcázar A, Portillo-Carrasquer M, Delaspre F, Pazos-Gil M, Tamarit J, Ros J, Cabiscol E
Redox biology 2024 Oct;76:103339
Redox biology 2024 Oct;76:103339
Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.
Shen Z, Zhao L, Yoo SA, Lin Z, Zhang Y, Yang W, Piao J
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1810-1823
Vitamin D inhibits ferroptosis and mitigates the kidney injury of prediabetic mice by activating the Klotho/p53 signaling pathway.
Chen H, Zhang Y, Miao Y, Song H, Tang L, Liu W, Li W, Miao J, Li X
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1780-1792
Apoptosis : an international journal on programmed cell death 2024 Oct;29(9-10):1780-1792
NAT10 inhibition promotes ac4C-dependent ferroptosis to counteract sorafenib resistance in nasopharyngeal carcinoma.
Xue Z, Xie H, Shan Y, Zhang L, Cheng L, Chen W, Zhu R, Zhang K, Ni H, Zhang Z, You Y, You B
Cancer science 2024 Oct;115(10):3256-3272
Cancer science 2024 Oct;115(10):3256-3272
Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1.
Zhu H, Jiang CW, Zhang WL, Yang ZY, Sun G
Cell death discovery 2024 Oct 6;10(1):430
Cell death discovery 2024 Oct 6;10(1):430
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease.
Niu R, Lan J, Liang D, Xiang L, Wu J, Zhang X, Li Z, Chen H, Geng L, Xu W, Gong S, Yang M
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
Cell communication and signaling : CCS 2024 Oct 4;22(1):474
TRIB3 inhibition by palbociclib sensitizes prostate cancer to ferroptosis via downregulating SOX2/SLC7A11 expression.
Zhang Y, Liu C, Yang Y, Ren H, Ren T, Huang Y, Zhang S, Sun Q, Huang H
Cell death discovery 2024 Oct 3;10(1):425
Cell death discovery 2024 Oct 3;10(1):425
Hyperbaric Oxygen Improves Cognitive Impairment Induced by Hypoxia via Upregulating the Expression of Oleic Acid and MBOAT2 of Mice.
Li Z, Fu J, Jiang K, Gao J, Guo Y, Li C, Zhao L, Nam J, Gao H
Antioxidants (Basel, Switzerland) 2024 Oct 29;13(11)
Antioxidants (Basel, Switzerland) 2024 Oct 29;13(11)
A respiratory Streptococcus strain inhibits Acinetobacter baumannii from causing inflammatory damage through ferroptosis.
Sun Y, Li S, Che Y, Liang H, Guo Y, Xiao C
BMC microbiology 2024 Oct 28;24(1):437
BMC microbiology 2024 Oct 28;24(1):437
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Chen Y, Chen W, Dai Y, Yan X, Jiang C, Zhang F, Zhang M, Hu X, Zhao J, Wu T, Li S, Han S, Chen X
Food & function 2024 Oct 28;15(21):10811-10822
Food & function 2024 Oct 28;15(21):10811-10822
Succinylated Type I Collagen Regulates Ferroptosis to Attenuate Skin Photoaging.
Zhang W, Zheng Z, Wang T, Yang X, Zhao J, Zhong Y, Peng X, Zhou Y
ACS applied materials & interfaces 2024 Oct 23;16(42):56744-56761
ACS applied materials & interfaces 2024 Oct 23;16(42):56744-56761
The Protective Effects of Polygala tenuifolia and Tenuifolin on Corticosterone-Evoked Ferroptosis, Oxidative Stress, and Neuroinflammation: Insights from Molecular Dynamics Simulations and In Vitro Experiments.
Xue C, He Z, Zeng M, Wang Z, Chen Q, Qin F, Chen M, Ye H, Chen J
Foods (Basel, Switzerland) 2024 Oct 23;13(21)
Foods (Basel, Switzerland) 2024 Oct 23;13(21)
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells.
Wu H, Zou L, Jin Y, Wang G, Cho WC, Li W, Cai Y, Song G
Archives of biochemistry and biophysics 2024 Nov;761:110188
Archives of biochemistry and biophysics 2024 Nov;761:110188
The protective role of RACK1 in hepatic ischemia‒reperfusion injury-induced ferroptosis.
Yang Z, Gao W, Yang K, Chen W, Chen Y
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Nov;73(11):1961-1979
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Nov;73(11):1961-1979
Metformin suppresses metabolic dysfunction-associated fatty liver disease by ferroptosis and apoptosis via activation of oxidative stress.
Li Z, Cui C, Xu L, Ding M, Wang Y
Free radical research 2024 Nov;58(11):686-701
Free radical research 2024 Nov;58(11):686-701
CBR-470-1 protects against cardiomyocyte death in ischaemia/reperfusion injury by activating the Nrf2-GPX4 cascade.
Qiu ZY, Shi KN, Li HH, Zhang B
Toxicology and applied pharmacology 2024 Nov;492:117113
Toxicology and applied pharmacology 2024 Nov;492:117113
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Fan YG, Ge RL, Ren H, Jia RJ, Wu TY, Lei XF, Wu Z, Zhou XB, Wang ZY
Pharmacological research 2024 Nov;209:107404
Pharmacological research 2024 Nov;209:107404
Isoliquiritigenin alleviates SLC7A11-mediated efferocytosis inhibition to promote wounds healing in diabetes.
Gong X, Cai J, Zheng W, Huang J, Chen T, Chen W, Zheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117578
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117578
Licochalcone A decreases cancer cell proliferation and enhances ferroptosis in acute myeloid leukemia through suppressing the IGF2BP3/MDM2 cascade.
Han P, Wei S, Wang H, Cai Y
Annals of hematology 2024 Nov;103(11):4511-4524
Annals of hematology 2024 Nov;103(11):4511-4524
ML385 promotes ferroptosis and radiotherapy sensitivity by inhibiting the NRF2-SLC7A11 pathway in esophageal squamous cell carcinoma.
Yan L, Hu H, Feng L, Li Z, Zheng C, Zhang J, Yin X, Li B
Medical oncology (Northwood, London, England) 2024 Nov 7;41(12):309
Medical oncology (Northwood, London, England) 2024 Nov 7;41(12):309
GDF15 attenuates sepsis-induced myocardial dysfunction by inhibiting cardiomyocytes ferroptosis via the SOCS1/GPX4 signaling pathway.
Li X, Sun H, Zhang L, Liang H, Zhang B, Yang J, Peng X, Sun J, Zhou Y, Zhai M, Jiang L, Zhu H, Duan W
European journal of pharmacology 2024 Nov 5;982:176894
European journal of pharmacology 2024 Nov 5;982:176894
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
Wang S, Zhang S, Li X, Leng C, Li X, Lv J, Zhao S, Qiu W, Guo J
Human genomics 2024 Nov 5;18(1):121
Human genomics 2024 Nov 5;18(1):121
Echinacoside Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Inhibiting Ferroptosis via Nrf2/HMOX1 Pathway.
Yan Y, Yang N, Qin F, Hao Y
Biomedicines 2024 Nov 28;12(12)
Biomedicines 2024 Nov 28;12(12)
Matrine protects against experimental autoimmune encephalomyelitis through modulating microglial ferroptosis.
Feng F, Li X, Wang W, Dou M, Li S, Jin X, Chu Y, Zhu L
Biochemical and biophysical research communications 2024 Nov 26;735:150651
Biochemical and biophysical research communications 2024 Nov 26;735:150651
Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2.
Wei J, Chai Q, Qin Y, Li L, Guo C, Lu Z, Liu H
Molecular medicine (Cambridge, Mass.) 2024 Nov 21;30(1):224
Molecular medicine (Cambridge, Mass.) 2024 Nov 21;30(1):224
KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11.
Li Y, Niu L, Zheng D, Zhang X, Feng L, Fu J
Communications biology 2024 Nov 18;7(1):1530
Communications biology 2024 Nov 18;7(1):1530
NEDD4L contributes to ferroptosis and cell growth inhibition in esophageal squamous cell carcinoma by facilitating xCT ubiquitination.
Chen Z, Wang W, Hou J, Gao C, Song M, Zhao Z, Guan R, Chen J, Wu H, Abdul Razak SR, Han T, Zhang J, Wang L, Ahmad NH, Li X
Cell death discovery 2024 Nov 18;10(1):473
Cell death discovery 2024 Nov 18;10(1):473
Huperzine A protected against ferroptosis via activating PI3K/Akt signaling in lipopolysaccharide induced acute lung injury.
Shi J, Chen W, Tang J, Zhang C, Qi M, Zheng X, Wang J, Liu Q, Liu L, Chen X, Han Z
European journal of pharmacology 2024 Nov 15;983:177004
European journal of pharmacology 2024 Nov 15;983:177004
Total extracts from Abelmoschus manihot (L.) alleviate radiation-induced cardiomyocyte ferroptosis via regulating redox imbalances mediated by the NOX4/xCT/GPX4 axis.
Xu Z, Wang Y, Yang W, Han W, Ma B, Zhao Y, Bao T, Zhang Q, Lin X
Journal of ethnopharmacology 2024 Nov 15;334:118582
Journal of ethnopharmacology 2024 Nov 15;334:118582
Carthamin yellow alleviates dextran sodium sulfate-induced ulcerative colitis by repairing the intestinal barrier and activating the Nrf2/GPX4 axis.
Bian W, Wei L, Wang K
International immunopharmacology 2024 Nov 15;141:113020
International immunopharmacology 2024 Nov 15;141:113020
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Huang P, Zhao H, Dai H, Li J, Pan X, Pan W, Xia C, Liu F
Cell death & disease 2024 Nov 14;15(11):826
Cell death & disease 2024 Nov 14;15(11):826
HIF-2α/TFR1 mediated iron homeostasis disruption aggravates cartilage endplate degeneration through ferroptotic damage and mtDNA release: A new mechanism of intervertebral disc degeneration.
Jing X, Wang W, He X, Liu X, Yang X, Su C, Shao Y, Ge Z, Wang H, Cui X
Journal of orthopaedic translation 2024 May;46:65-78
Journal of orthopaedic translation 2024 May;46:65-78
N-acetylcysteine Protects Against Myocardial Ischemia-Reperfusion Injury Through Anti-ferroptosis in Type 1 Diabetic Mice.
Zhou D, Yang Y, Chen J, Zhou J, He J, Liu D, Zhang A, Yuan B, Jiang Y, Xia W, Han R, Xia Z
Cardiovascular toxicology 2024 May;24(5):481-498
Cardiovascular toxicology 2024 May;24(5):481-498
Co-exposure of arsenic and polystyrene-nanoplastics induced kidney injury by disrupting mitochondrial homeostasis and mtROS-mediated ferritinophagy and ferroptosis.
Zhong G, Qiao B, He Y, Liu H, Hong P, Rao G, Tang L, Tang Z, Hu L
Pesticide biochemistry and physiology 2024 May;201:105904
Pesticide biochemistry and physiology 2024 May;201:105904
Injectable, anti-collapse, adhesive, plastic and bioactive bone graft substitute promotes bone regeneration by moderating oxidative stress in osteoporotic bone defect.
Huang L, Zhang S, Bian M, Xiang X, Xiao L, Wang J, Lu S, Chen W, Zhang C, Mo G, Jiang L, Li Y, Zhang J
Acta biomaterialia 2024 May;180:82-103
Acta biomaterialia 2024 May;180:82-103
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis.
Wang Q, Liu C, Chen M, Zhao J, Wang D, Gao P, Zhang C, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116560
Iron (II)-based metal-organic framework nanozyme for boosting tumor ferroptosis through inhibiting DNA damage repair and system Xc().
Xue P, Zhuang H, Bai T, Zeng X, Deng J, Shao S, Yan S
Journal of nanobiotechnology 2024 May 8;22(1):228
Journal of nanobiotechnology 2024 May 8;22(1):228
Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway.
Tao Y, Zhao Q, Lu C, Yong W, Xu M, Wang Z, Leng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23678
Quercetin Inhibits Neuronal Pyroptosis and Ferroptosis by Modulating Microglial M1/M2 Polarization in Atherosclerosis.
Li H, Cao Z, Liu C, Wang Y, Wang L, Tang Y, Yao P
Journal of agricultural and food chemistry 2024 May 29;72(21):12156-12170
Journal of agricultural and food chemistry 2024 May 29;72(21):12156-12170
Non-cytotoxic nanomolar concentration of arctigenin protects neuronal cells from chemotherapy-induced ferroptosis by regulating SLC7A11-cystine-cysteine axis.
Li Z, Cao L, Han K, Fan L, Zhao C, Yin S, Hu H
Biochemical and biophysical research communications 2024 May 28;710:149895
Biochemical and biophysical research communications 2024 May 28;710:149895
Anti-ferroptosis exosomes engineered for targeting M2 microglia to improve neurological function in ischemic stroke.
Wang Y, Liu Z, Li L, Zhang Z, Zhang K, Chu M, Liu Y, Mao X, Wu D, Xu D, Zhao J
Journal of nanobiotechnology 2024 May 27;22(1):291
Journal of nanobiotechnology 2024 May 27;22(1):291
Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma.
Wang S, Li Y, Lin Y, Li J, Guo L, Wang H, Lin X, Liu Z, Zhang B, Liao Z, Zhang Z
Scientific reports 2024 May 25;14(1):11985
Scientific reports 2024 May 25;14(1):11985
Lizhong decoction ameliorates ulcerative colitis by inhibiting ferroptosis of enterocytes via the Nrf2/SLC7A11/GPX4 pathway.
Li W, Wang Y, Zhang Y, Fan Y, Liu J, Zhu K, Jiang S, Duan J
Journal of ethnopharmacology 2024 May 23;326:117966
Journal of ethnopharmacology 2024 May 23;326:117966
Pharmacological inhibition of p300 ameliorates steatosis, inflammation, and fibrosis in mice with non-alcoholic steatohepatitis.
Kim JY, Yang AY, Kim K, Kwon HH, Leem J, Kim YA
Heliyon 2024 May 15;10(9):e30908
Heliyon 2024 May 15;10(9):e30908
IL-1α facilitates GSH synthesis to counteract oxidative stress in oral squamous cell carcinoma under glucose-deprivation.
Ji Y, Zhang Z, Zhao X, Li Z, Hu X, Zhang M, Pan X, Wang X, Chen W
Cancer letters 2024 May 1;589:216833
Cancer letters 2024 May 1;589:216833
Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance.
Lin X, Zhang Q, Li Q, Deng J, Shen S, Tang M, Ye X, Ji C, Yang Y, Chen Y, Zeng L, Zhao J, Kouwenhoven MBN, Lucero-Prisno DE 3rd, Huang J, Li Y, Zhang B, Hu J
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101032
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101032
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Xie HB, Guo JH, Yang MM, Wang JT
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Circular RNA ANKIB1 alleviates hypoxia-induced cardiomyocyte injury by modulating miR-452-5p/SLC7A11 axis.
Li G, Tang X, Tang H
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Mar;33(3):261-272
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Mar;33(3):261-272
Boosting the synergism between cancer ferroptosis and immunotherapy via targeted stimuli-responsive liposomes.
Gao Z, Zhang J, Hou Y, Lu J, Liang J, Gao Y, Li B, Gao S, Zhao Y, Gao M, Chen J
Biomaterials 2024 Mar;305:122442
Biomaterials 2024 Mar;305:122442
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Yang Y, Chen Y, Tang H, Zhang Z, Zhou X, Xu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
GSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4.
Chen Y, Feng Y, Lin Y, Zhou X, Wang L, Zhou Y, Lin K, Cai L
British journal of cancer 2024 Mar;130(5):755-768
British journal of cancer 2024 Mar;130(5):755-768
LuQi formula attenuates Cardiomyocyte ferroptosis via activating Nrf2/GPX4 signaling axis in heart failure.
Cheng P, Wang X, Liu Q, Yang T, Dai E, Sha W, Qu H, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Mar;125:155357
Ferroptosis in Osteocytes as a Target for Protection Against Postmenopausal Osteoporosis.
Jiang Z, Qi G, He X, Yu Y, Cao Y, Zhang C, Zou W, Yuan H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2307388
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(12):e2307388
VDR Activation Attenuates Renal Tubular Epithelial Cell Ferroptosis by Regulating Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy.
Wang H, Yu X, Liu D, Qiao Y, Huo J, Pan S, Zhou L, Wang R, Feng Q, Liu Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305563
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Mar;11(10):e2305563
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer.
Han X, Wang D, Yang L, Wang N, Shen J, Wang J, Zhang L, Chen L, Gao S, Zong WX, Wang Y
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 26;121(13):e2319429121
Proceedings of the National Academy of Sciences of the United States of America 2024 Mar 26;121(13):e2319429121
The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
Chen Q, Zhang T, Zeng R, Zhang K, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G
Scientific reports 2024 Mar 20;14(1):6655
Scientific reports 2024 Mar 20;14(1):6655
TfR1 mediated iron metabolism dysfunction as a potential therapeutic target for osteoarthritis.
Wang W, Ma Z, Feng X, Ren J, Sun S, Shao Y, Zhang W, Yang X, Zhang J, Jing X
Arthritis research & therapy 2024 Mar 16;26(1):71
Arthritis research & therapy 2024 Mar 16;26(1):71
Pentoxifylline protects against cerebral ischaemia-reperfusion injury through ferroptosis regulation via the Nrf2/SLC7A11/GPX4 signalling pathway.
Li P, Chen JM, Ge SH, Sun ML, Lu JD, Liu F, Wang LL, Zhang X, Wang XP
European journal of pharmacology 2024 Mar 15;967:176402
European journal of pharmacology 2024 Mar 15;967:176402
Mesenchymal stem cells inhibit ferroptosis by activating the Nrf2 antioxidation pathway in severe acute pancreatitis-associated acute lung injury.
Yang H, Liu Y, Yao J, Wang Y, Wang L, Ren P, Bai B, Wen Q
European journal of pharmacology 2024 Mar 15;967:176380
European journal of pharmacology 2024 Mar 15;967:176380
Cell-Cycle-related Protein Centromere Protein F Deficiency Inhibits Cervical Cancer Cell Growth by Inducing Ferroptosis Via Nrf2 Inactivation.
Tang XH, Zhao TN, Guo L, Liu XY, Zhang WN, Zhang P
Cell biochemistry and biophysics 2024 Jun;82(2):997-1006
Cell biochemistry and biophysics 2024 Jun;82(2):997-1006
Widespread S-persulfidation in activated macrophages as a protective mechanism against oxidative-inflammatory stress.
Salti T, Braunstein I, Haimovich Y, Ziv T, Benhar M
Redox biology 2024 Jun;72:103125
Redox biology 2024 Jun;72:103125
Nicorandil Regulates Ferroptosis and Mitigates Septic Cardiomyopathy via TLR4/SLC7A11 Signaling Pathway.
Lu JS, Wang JH, Han K, Li N
Inflammation 2024 Jun;47(3):975-988
Inflammation 2024 Jun;47(3):975-988
Photodynamic therapy inhibits cancer progression and induces ferroptosis and apoptosis by targeting P53/GPX4/SLC7A11 signaling pathways in cholangiocarcinoma.
Yan X, Li Z, Chen H, Yang F, Tian Q, Zhang Y
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
Photodiagnosis and photodynamic therapy 2024 Jun;47:104104
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Zhao J, Shen J, Mao L, Yang T, Liu J, Hongbin S
Oncogene 2024 Jun;43(27):2104-2114
Oncogene 2024 Jun;43(27):2104-2114
Licochalcone A alleviates ferroptosis in doxorubicin-induced cardiotoxicity via the PI3K/AKT/MDM2/p53 pathway.
Chen G, Luo S, Guo H, Lin J, Xu S
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4247-4262
Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells.
Torres-Velarde JM, Allen KN, Salvador-Pascual A, Leija RG, Luong D, Moreno-Santillán DD, Ensminger DC, Vázquez-Medina JP
Free radical biology & medicine 2024 Jun;218:82-93
Free radical biology & medicine 2024 Jun;218:82-93
Targeting NKAα1 to treat Parkinson's disease through inhibition of mitophagy-dependent ferroptosis.
Zhang X, Li G, Chen H, Nie XW, Bian JS
Free radical biology & medicine 2024 Jun;218:190-204
Free radical biology & medicine 2024 Jun;218:190-204
Botulinum toxin A attenuates osteoarthritis development via inhibiting chondrocyte ferroptosis through SLC7Al1/GPX4 axis.
Zeng L, Liu Y, Wang Q, Wan H, Meng X, Tu P, Chen H, Luo A, Hu P, Ding X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167215
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167215
Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.
Zhang Q, Zhou J, Zhai D, Jiang Q, Yang M, Zhou M
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167152
Hypoxia-inducible factor 3α1 increases epithelial-to-mesenchymal transition and iron uptake to drive colorectal cancer liver metastasis.
Villareal LB, Falcon DM, Xie L, Xue X
British journal of cancer 2024 Jun;130(12):1904-1915
British journal of cancer 2024 Jun;130(12):1904-1915
MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.
Shi J, Yang MM, Yang S, Fan F, Zheng G, Miao Y, Hua Y, Zhang J, Cheng Y, Liu S, Guo Y, Guo L, Yang X, Fan G, Ma C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489
N6022 attenuates cerebral ischemia/reperfusion injury-induced microglia ferroptosis by promoting Nrf2 nuclear translocation and inhibiting the GSNOR/GSTP1 axis.
Duan WL, Ma YP, Wang XJ, Ma CS, Han B, Sheng ZM, Dong H, Zhang LY, Li PA, Zhang BG, He MT
European journal of pharmacology 2024 Jun 5;972:176553
European journal of pharmacology 2024 Jun 5;972:176553
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway.
Fan Y, Zhang Y, Qin D, Shu X
Cell & bioscience 2024 Jun 5;14(1):71
Cell & bioscience 2024 Jun 5;14(1):71
Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload.
Wang C, Zhao H, Liu Y, Qu M, Lv S, He G, Liang H, Chen K, Yang L, He Y, Ou C
Ecotoxicology and environmental safety 2024 Jun 15;278:116404
Ecotoxicology and environmental safety 2024 Jun 15;278:116404
α-Ketoglutarate alleviates osteoarthritis by inhibiting ferroptosis via the ETV4/SLC7A11/GPX4 signaling pathway.
He R, Wei Y, Peng Z, Yang J, Zhou Z, Li A, Wu Y, Wang M, Li X, Zhao D, Liu Z, Dong H, Leng X
Cellular & molecular biology letters 2024 Jun 14;29(1):88
Cellular & molecular biology letters 2024 Jun 14;29(1):88
ERRFI1 exacerbates hepatic ischemia reperfusion injury by promoting hepatocyte apoptosis and ferroptosis in a GRB2-dependent manner.
Zhao H, Mao H
Molecular medicine (Cambridge, Mass.) 2024 Jun 11;30(1):82
Molecular medicine (Cambridge, Mass.) 2024 Jun 11;30(1):82
HMOX1 regulates ferroptosis via mic14 and its impact on chemotherapy resistance in small-cell lung cancer.
Sun Y, Zhang J
Anti-cancer drugs 2024 Jun 1;35(5):397-411
Anti-cancer drugs 2024 Jun 1;35(5):397-411
Sleeve gastrectomy links the attenuation of diabetic kidney disease to the inhibition of renal tubular ferroptosis through down-regulating TGF-β1/Smad3 signaling pathway.
Liu C, Zhong M, Jin X, Zhu J, Cheng Y, Li L, Xu Q, Liu Q, Ding H, Zhang G
Journal of endocrinological investigation 2024 Jul;47(7):1763-1776
Journal of endocrinological investigation 2024 Jul;47(7):1763-1776
HDAC inhibitors activate lipid peroxidation and ferroptosis in gastric cancer.
Jenke R, Oliinyk D, Zenz T, Körfer J, Schäker-Hübner L, Hansen FK, Lordick F, Meier-Rosar F, Aigner A, Büch T
Biochemical pharmacology 2024 Jul;225:116257
Biochemical pharmacology 2024 Jul;225:116257
DDX39B protects against sorafenib-induced ferroptosis by facilitating the splicing and cytoplasmic export of GPX4 pre-mRNA in hepatocellular carcinoma.
Li Q, Yuan H, Zhao G, Ou D, Zhang J, Li L, Li S, Feng T, Gu R, Kou Q, Wang Q, Li S, Wang G, Zhao M, Yu H, Qu J, Lin P, Li K
Biochemical pharmacology 2024 Jul;225:116251
Biochemical pharmacology 2024 Jul;225:116251
Salvia miltiorrhiza Bge. processed with porcine cardiac blood inhibited GLRX5-mediated ferroptosis alleviating cerebral ischemia-reperfusion injury.
Zhou S, Wang Z, Wang T, Peng C, Zhang J, Liu C, Xu J, Zhang Y, Zhang L, Luo L, Yan X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155622
Baicalin promotes the sensitivity of NSCLC to cisplatin by regulating ferritinophagy and macrophage immunity through the KEAP1-NRF2/HO-1 pathway.
Chen Y, Bao S, Wang Z, Fang Z, Tang H
European journal of medical research 2024 Jul 26;29(1):387
European journal of medical research 2024 Jul 26;29(1):387
Quercetin inhibits neuronal Ferroptosis and promotes immune response by targeting lipid metabolism-related gene PTGS2 to alleviate breast cancer-related depression.
Zhu Q, Han Y, He Y, Meng P, Fu Y, Yang H, He G, Long M, Shi Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155560
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul 25;130:155560
Ultrasound-responsive Bi(2)MoO(6)-MXene heterojunction as ferroptosis inducers for stimulating immunogenic cell death against ovarian cancer.
Cheng S, Zhou T, Luo Y, Zhang J, Dong K, Zhang Q, Shu W, Zhang T, Zhang Q, Shi R, Yao Y, Wang H
Journal of nanobiotechnology 2024 Jul 11;22(1):408
Journal of nanobiotechnology 2024 Jul 11;22(1):408
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
Gui S, Yu W, Xie J, Peng L, Xiong Y, Song Z, Luo H, Xiao J, Yuan S, Cheng Z
Endocrine connections 2024 Jul 1;13(7)
Endocrine connections 2024 Jul 1;13(7)
An investigation of the distributions of ferroptosis and necroptosis mediators in the maternal-fetal interface at different days of rat pregnancy.
Tatar M, Tüfekci KK
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
Anatomia, histologia, embryologia 2024 Jan;53(1):e12991
Selenomethionine protects the liver from dietary deoxynivalenol exposure via Nrf2/PPARγ-GPX4-ferroptosis pathway in mice.
Fan S, Lin L, Li P, Tian H, Shen J, Zhou L, Zhao Q, Zhang J, Qin Y, Tang C
Toxicology 2024 Jan;501:153689
Toxicology 2024 Jan;501:153689
RETRACTED ARTICLE: Liquiritin reduces ferroptosis in doxorubicin-induced cardiotoxicity through targeting SLC7A11/GPX4 pathway.
Wang M, Liu M, Tang L, Shen L, Xiao J, Li R
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):627
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):627
Arvanil induces ferroptosis of hepatocellular carcinoma by binding to MICU1.
Deng X, Gui Y, Zhao L, Li N, Li L
Cancer gene therapy 2024 Jan;31(1):148-157
Cancer gene therapy 2024 Jan;31(1):148-157
Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.
Wang W, Yu R, Wu C, Li Q, Chen J, Xiao Y, Chen H, Song J, Ji M, Zuo Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016
Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma.
Wang HH, Fan SQ, Zhan YT, Peng SP, Wang WY
International journal of biological macromolecules 2024 Jan;254(Pt 3):127976
International journal of biological macromolecules 2024 Jan;254(Pt 3):127976
Ambra1 in exosomes secreted by HK-2 cells damaged by supersaturated oxalate induce mitophagy and autophagy-ferroptosis in normal HK-2 cells to participate in the occurrence of kidney stones.
Su X, Song C, He Z, Song Q, Meng L, Dong C, Zhou J, Ke H, Xiong Y, Liu J, Liao W, Yang S
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Biochimica et biophysica acta. Molecular cell research 2024 Jan;1871(1):119604
Niujiao Dihuang Jiedu decoction promotes SLC7A11 m5C methylation modification against ferroptosis in acute-on-chronic liver failure.
Huang L, Liu J, Jin Y, Qiu Y, Qin X, Wu S, Chen D, Bie C, Kuang W, Liu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155136
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155136
Polyphyllin I induced ferroptosis to suppress the progression of hepatocellular carcinoma through activation of the mitochondrial dysfunction via Nrf2/HO-1/GPX4 axis.
Yang R, Gao W, Wang Z, Jian H, Peng L, Yu X, Xue P, Peng W, Li K, Zeng P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155135
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;122:155135
Chrysophanol induces apoptosis and ferroptosis of gastric cancer cells by targeted regulation of mTOR.
Xi S, Ding W, Weng D, Zeng Y, Gao K, Wu Q, Huang G, Li Y, Yue H
Chemical biology & drug design 2024 Jan;103(1):e14417
Chemical biology & drug design 2024 Jan;103(1):e14417
Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.
Yu S, Mu Y, Wang K, Wang L, Wang C, Yang Z, Liu Y, Li S, Zhang M
Chemico-biological interactions 2024 Jan 5;387:110812
Chemico-biological interactions 2024 Jan 5;387:110812
SNRPB promotes the progression of hepatocellular carcinoma via regulating cell cycle, oxidative stress, and ferroptosis.
Wang X, Zhang H, Guo Z, Wang J, Lu C, Wang J, Jin R, Mo Z
Aging 2024 Jan 5;16(1):348-366
Aging 2024 Jan 5;16(1):348-366
In silico prediction and experimental validation to reveal the protective mechanism of Puerarin against excessive extracellular matrix accumulation through inhibiting ferroptosis in diabetic nephropathy.
Hou B, Ma P, Yang X, Zhao X, Zhang L, Zhao Y, He P, Zhang L, Du G, Qiang G
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117281
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117281
Pan-Cancer Analysis Reveals Disulfidoptosis-Associated Genes as Promising Immunotherapeutic Targets: Insights Gained from Bulk Omics and Single-Cell Sequencing Validation.
Xu B, Li M, Weng N, Zhou C, Chen Y, Wei J, Fu L
Biomedicines 2024 Jan 24;12(2)
Biomedicines 2024 Jan 24;12(2)
Sodium Butyrate Alleviates Free Fatty Acid-Induced Steatosis in Primary Chicken Hepatocytes via Regulating the ROS/GPX4/Ferroptosis Pathway.
Cheng X, Hu Y, Yu X, Chen J, Guo X, Cao H, Hu G, Zhuang Y
Antioxidants (Basel, Switzerland) 2024 Jan 23;13(2)
Antioxidants (Basel, Switzerland) 2024 Jan 23;13(2)
LncRNA MEG3 suppresses erastin-induced ferroptosis of chondrocytes via regulating miR-885-5p/SLC7A11 axis.
Zhu C, Chen B, He X, Li W, Wang S, Zhu X, Li Y, Wan P, Li X
Molecular biology reports 2024 Jan 18;51(1):139
Molecular biology reports 2024 Jan 18;51(1):139
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Yu S, Xiong W, Xu W, Chen Y
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Zou W, Wang X, Xia X, Zhang T, Nie M, Xiong J, Fang X
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Identification and validation of a disulfidptosis-related genes prognostic signature in lung adenocarcinoma.
Zhang Y, Sun J, Li M, Hou L, Wang Z, Dong H, Xu W, Jiang R, Geng Y, Guan C, Zhu Z, Wang H, Gong Q, Zhang G
Heliyon 2024 Jan 15;10(1):e23502
Heliyon 2024 Jan 15;10(1):e23502
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J
Tissue & cell 2024 Feb;86:102290
Tissue & cell 2024 Feb;86:102290
Everolimus inhibits hepatoblastoma by inducing autophagy-dependent ferroptosis.
Huang H, Yan J, Xu X, Feng Y, Liu H, Liu J, Xie M, Chen L, Xiang D, Peng W, Zeng L, Zeng Y, Chen F, Zhang S, Liu Q
Drug development research 2024 Feb;85(1):e22140
Drug development research 2024 Feb;85(1):e22140
Heterogeneous ferroptosis susceptibility of macrophages caused by focal iron overload exacerbates rheumatoid arthritis.
Liu Y, Luo X, Chen Y, Dang J, Zeng D, Guo X, Weng W, Zhao J, Shi X, Chen J, Dong B, Zhong S, Ren J, Li Y, Wang J, Zhang J, Sun J, Xu H, Lu Y, Brand D, Zheng SG, Pan Y
Redox biology 2024 Feb;69:103008
Redox biology 2024 Feb;69:103008
Excessive SOX8 reprograms energy and iron metabolism to prime hepatocellular carcinoma for ferroptosis.
Yang X, Gu C, Cai J, Li F, He X, Luo L, Xiao W, Hu B, Hu J, Qian H, Ren S, Zhang L, Zhu X, Yang L, Yang J, Yang Z, Zheng Y, Huang X, Wang Z
Redox biology 2024 Feb;69:103002
Redox biology 2024 Feb;69:103002
Inhibition of the RBMS1/PRNP axis improves ferroptosis resistance-mediated oxaliplatin chemoresistance in colorectal cancer.
Xu Y, Hao J, Chen Q, Qin Y, Qin H, Ren S, Sun C, Zhu Y, Shao B, Zhang J, Wang H
Molecular carcinogenesis 2024 Feb;63(2):224-237
Molecular carcinogenesis 2024 Feb;63(2):224-237
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers.
Kojima Y, Tanaka M, Sasaki M, Ozeki K, Shimura T, Kubota E, Kataoka H
Journal of gastroenterology 2024 Feb;59(2):81-94
Journal of gastroenterology 2024 Feb;59(2):81-94
Nrf2 protects against cartilage endplate degeneration through inhibiting NCOA4‑mediated ferritinophagy.
Ma Z, Lu H, Feng X, Du T, Li J, Zhang Q, Gu X, Shao Y, Jing X, Su C
International journal of molecular medicine 2024 Feb;53(2)
International journal of molecular medicine 2024 Feb;53(2)
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J
Oncology reports 2024 Feb;51(2)
Oncology reports 2024 Feb;51(2)
Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway.
Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
Acta pharmacologica Sinica 2024 Feb;45(2):248-267
In situ generation of hybrid alginate hydrogels for enhanced breast tumor ferrotherapy through multiplex magnifying redox imbalances.
Zhuang H, Xue P, Shao S, Zeng X, Yan S
International journal of biological macromolecules 2024 Feb;258(Pt 2):128952
International journal of biological macromolecules 2024 Feb;258(Pt 2):128952
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Dan Z, Shi X, Shu C, Zhu R, Wang Y, Zhu H
Cellular signalling 2024 Feb;114:111001
Cellular signalling 2024 Feb;114:111001
An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression.
Zhang H, Wang J, Xiang X, Xie C, Lu X, Guo H, Sun Y, Shi Z, Song H, Qiu N, Xu X
Pharmaceutics 2024 Feb 8;16(2)
Pharmaceutics 2024 Feb 8;16(2)
Inhibiting LCN2 can suppress the development of NSCLC by promoting ferroptosis.
Pan Z, Li B, Lu P, Rong G, Wang X
Gene 2024 Feb 5;894:148026
Gene 2024 Feb 5;894:148026
Machine learning reveals diverse cell death patterns in lung adenocarcinoma prognosis and therapy.
Wang S, Wang R, Hu D, Zhang C, Cao P, Huang J
NPJ precision oncology 2024 Feb 26;8(1):49
NPJ precision oncology 2024 Feb 26;8(1):49
Inhibition of ferroptosis reverses heart failure with preserved ejection fraction in mice.
Xiong Y, Liu X, Jiang L, Hao T, Wang Y, Li T
Journal of translational medicine 2024 Feb 24;22(1):199
Journal of translational medicine 2024 Feb 24;22(1):199
Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma.
Wang S, Zhu L, Li T, Lin X, Zheng Y, Xu D, Guo Y, Zhang Z, Fu Y, Wang H, Wang X, Zou T, Shen X, Zhang L, Lai N, Lu L, Qin L, Dong Q
Cell reports. Medicine 2024 Feb 20;5(2):101415
Cell reports. Medicine 2024 Feb 20;5(2):101415
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
Zhou W, Lim A, Elmadbouh OHM, Edderkaoui M, Osipov A, Mathison AJ, Urrutia R, Liu T, Wang Q, Pandol SJ
Free radical biology & medicine 2024 Feb 20;212:493-504
Free radical biology & medicine 2024 Feb 20;212:493-504
A novel tsRNA-5008a promotes ferroptosis in cardiomyocytes that causes atrial structural remodeling predisposed to atrial fibrillation.
Xie L, Zhao Z, Xia H, Su S, He L, Huang Z, Li Y, Gao M, Chen J, Peng J, Ruan Y
Experimental cell research 2024 Feb 15;435(2):113923
Experimental cell research 2024 Feb 15;435(2):113923
Identification of SLC40A1, LCN2, CREB5, and SLC7A11 as ferroptosis-related biomarkers in alopecia areata through machine learning.
Xu W, Wei D, Song X
Scientific reports 2024 Feb 15;14(1):3800
Scientific reports 2024 Feb 15;14(1):3800
Oridonin-induced ferroptosis and apoptosis: a dual approach to suppress the growth of osteosarcoma cells.
Zhang F, Hao Y, Yang N, Liu M, Luo Y, Zhang Y, Zhou J, Liu H, Li J
BMC cancer 2024 Feb 12;24(1):198
BMC cancer 2024 Feb 12;24(1):198
β-Lapachone induces ferroptosis of colorectal cancer cells via NCOA4-mediated ferritinophagy by activating JNK pathway.
Zhao L, Miao H, Quan M, Wang S, Zhang Y, Zhou H, Zhang X, Lin Z, Piao J
Chemico-biological interactions 2024 Feb 1;389:110866
Chemico-biological interactions 2024 Feb 1;389:110866
Laminin-α2 chain deficiency in skeletal muscle causes dysregulation of multiple cellular mechanisms.
Martins SG, Ribeiro V, Melo C, Paulino-Cavaco C, Antonini D, Dayalan Naidu S, Murtinheira F, Fonseca I, Saget B, Pita M, Fernandes DR, Gameiro Dos Santos P, Rodrigues G, Zilhão R, Herrera F, Dinkova-Kostova AT, Carlos AR, Thorsteinsdóttir S
Life science alliance 2024 Dec;7(12)
Life science alliance 2024 Dec;7(12)
PRKN-mediated the ubiquitination of IQGAP3 regulates cell growth, metastasis and ferroptosis in early-onset colorectal cancer.
Chen G, Cong L, Gu C, Li P
Journal of bioenergetics and biomembranes 2024 Dec;56(6):645-655
Journal of bioenergetics and biomembranes 2024 Dec;56(6):645-655
METTL3 silencing inhibits ferroptosis to suppress ovarian fibrosis in PCOS by upregulating m6A modification of GPX4.
Shen C, Jiang Y, Lin J, Guo Q, Fang D
Journal of molecular histology 2024 Dec;55(6):1163-1175
Journal of molecular histology 2024 Dec;55(6):1163-1175
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Zhang J, Wang T, Zhang H, Li N, Liu B, Fang L
Toxicology and applied pharmacology 2024 Dec;493:117148
Toxicology and applied pharmacology 2024 Dec;493:117148
Sirt6 overexpression relieves ferroptosis and delays the progression of diabetic nephropathy via Nrf2/GPX4 pathway.
Du L, Guo C, Zeng S, Yu K, Liu M, Li Y
Renal failure 2024 Dec;46(2):2377785
Renal failure 2024 Dec;46(2):2377785
β-Hydroxybutyrate Protects Against Cisplatin-Induced Renal Damage via Regulating Ferroptosis.
Tian R, Tang S, Zhao J, Hao Y, Zhao L, Han X, Wang X, Zhang L, Li R, Zhou X
Renal failure 2024 Dec;46(1):2354918
Renal failure 2024 Dec;46(1):2354918
The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.
Zhao Y, Zheng G, Yang S, Liu S, Wu Y, Miao Y, Liang Z, Hua Y, Zhang J, Shi J, Li D, Cheng Y, Zhang Y, Chen Y, Fan G, Ma C
British journal of pharmacology 2024 Dec;181(23):4822-4844
British journal of pharmacology 2024 Dec;181(23):4822-4844
Puerarin alleviates symptoms of preeclampsia through the repression of trophoblast ferroptosis via the CREB/HO-1 pathway.
Yue X, Pang M, Chen Y, Cheng Z, Zhou R, Wang Y, Zha Z, Huang L
Placenta 2024 Dec;158:145-155
Placenta 2024 Dec;158:145-155
Ginsenoside compound K alleviates brain aging by inhibiting ferroptosis through modulation of the ASK1-MKK7-JNK signaling pathway.
Yan X, Bai X, Sun G, Duan Z, Fu R, Zeng W, Zhu C, Fan D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156239
Suyin Detoxification Granule alleviates trimethylamine N-oxide-induced tubular ferroptosis and renal fibrosis to prevent chronic kidney disease progression.
Ge H, Wei Y, Zhang W, Yong C, Chen Y, Zhou E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156195
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156195
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4-mediated ferroptosis.
Cao R, Feng Z, Mo J, Wu J, Li J, Li W, Wang Z, Ma Q, Wu Z, Zhou C
Cellular signalling 2024 Dec;124:111381
Cellular signalling 2024 Dec;124:111381
Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation.
Duan C, Li B, Liu H, Zhang Y, Yao X, Liu K, Wu X, Mao X, Wu H, Xu Z, Zhong Y, Hu Z, Gong Y, Xu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408945
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408945
To explore the protective mechanism of promethazine against hippocampal neuron injury based on network pharmacology and experimental verification.
Bai L, Li F
Medicine 2024 Dec 6;103(49):e40550
Medicine 2024 Dec 6;103(49):e40550
Gypenoside A-loaded mPEG-PLGA nanoparticles ameliorate high-glucose-induced retinal microvasculopathy by inhibiting ferroptosis.
Chen Q, Qiu FS, Xie W, Yu WY, Su ZA, Qin GM, Kang YK, Jiang SL, Yu CH
International journal of pharmaceutics 2024 Dec 5;666:124758
International journal of pharmaceutics 2024 Dec 5;666:124758
Simvastatin induces ferroptosis and activates anti-tumor immunity to sensitize anti-PD-1 immunotherapy in microsatellite stable gastric cancer.
Ning Y, Fang S, Zhang R, Fang J, Lin K, Ding Y, Nie H, Zhou J, Zhao Q, Ke H, Wang H, Wang F
International immunopharmacology 2024 Dec 5;142(Pt B):113244
International immunopharmacology 2024 Dec 5;142(Pt B):113244
CD39 inhibitor (POM-1) enhances radiosensitivity of esophageal squamous cell carcinoma (ESCC) cells by promoting apoptosis through the Bax/Bcl-2/Caspase 9/Caspase 3 pathway.
Wang Y, Zhang R, Huang X, He X, Geng S, Pan S, Guo W, Liu X, Dang Y, Qu J, Ma H, Zhao X
International immunopharmacology 2024 Dec 5;142(Pt B):113242
International immunopharmacology 2024 Dec 5;142(Pt B):113242
Inhibition of miR-9-3p facilitates ferroptosis by activating SAT1/p53 pathway in lung adenocarcinoma.
Wu A, Zhang A, Wang T, Chen J, Shi J
Translational lung cancer research 2024 Dec 31;13(12):3426-3442
Translational lung cancer research 2024 Dec 31;13(12):3426-3442
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
Liu Y, Li W, Tang H, Yang Z, Wei M, Zhou W, Li Z, Huang W
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
Protective Effects of Tormentic Acid on Unilateral Ureteral Obstruction-Induced Renal Injury, Inflammation, and Fibrosis: A Comprehensive Approach to Reducing Oxidative Stress, Apoptosis, and Ferroptosis.
Yang AY, Kim JY, Gwon MG, Kwon HH, Leem J, Jeon EJ
Antioxidants (Basel, Switzerland) 2024 Dec 25;14(1)
Antioxidants (Basel, Switzerland) 2024 Dec 25;14(1)
Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes.
Shi X, Xu J, Zhong X, Qian Y, Lin L, Fang Z, Ye B, Lyu Y, Zhang R, Zheng Z, Han J
Cell communication and signaling : CCS 2024 Dec 18;22(1):593
Cell communication and signaling : CCS 2024 Dec 18;22(1):593
REV-ERBα inhibitor rescues MPTP/MPP(+)-induced ferroptosis of dopaminergic neuron through regulating FASN/SCD1 signaling pathway.
Wang X, Wang M, Zhi H, Li J, Guo D
Heliyon 2024 Dec 15;10(23):e40388
Heliyon 2024 Dec 15;10(23):e40388
High glucose elevates intracellular calcium level and induces ferroptosis in glomerular endothelial cells through the miR-223-3p/ITPR3 pathway.
Wang D, Zhang L, Nan J, Wan S, Luo J, Li X, Chen W
Molecular and cellular endocrinology 2024 Dec 1;594:112384
Molecular and cellular endocrinology 2024 Dec 1;594:112384
Pharmacodynamic insights into maresin 1: Enhancing flap viability via the keap1/Nrf2 axis to control ROS-driven apoptosis and ferroptosis.
Fang P, Cheng S, Lai Y, Ma X, Lu K, Lu J, Li G, Yang E, Yang N, Gao W, Jiang R
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Dec 1;203:106923
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Dec 1;203:106923
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Wu X, Wu J
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Alkaliptosis induction counteracts paclitaxel-resistant ovarian cancer cells via ATP6V0D1-mediated ABCB1 inhibition.
Chen F, Lin J, Kang R, Tang D, Liu J
Molecular carcinogenesis 2024 Aug;63(8):1515-1527
Molecular carcinogenesis 2024 Aug;63(8):1515-1527
Curcumin inhibits PAT-induced renal ferroptosis via the p62/Keap1/Nrf2 signalling pathway.
Zhai J, Chen Z, Zhu Q, Guo Z, Sun X, Jiang L, Li J, Wang N, Yao X, Zhang C, Deng H, Wang S, Yang G
Toxicology 2024 Aug;506:153863
Toxicology 2024 Aug;506:153863
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Neurochemical research 2024 Aug;49(8):2131-2147
Neurochemical research 2024 Aug;49(8):2131-2147
Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc(-)-GSH-GPX4 signaling pathway in ferroptosis response.
Ni X, Gao C, Zhu X, Zhang X, Fang Y, Hao Z
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
Journal of applied toxicology : JAT 2024 Aug;44(8):1139-1152
PDLIM3 knockdown promotes ferroptosis in endometriosis progression via inducing Gli1 degradation and blocking Hedgehog signaling pathway.
Liu M, Wang X, Zhu J
Journal of assisted reproduction and genetics 2024 Aug;41(8):2117-2128
Journal of assisted reproduction and genetics 2024 Aug;41(8):2117-2128
Glutamine Mitigates Oxidative Stress-Induced Matrix Degradation, Ferroptosis, and Pyroptosis in Nucleus Pulposus Cells via Deubiquitinating and Stabilizing Nrf2.
Wu J, Han W, Zhang Y, Li S, Qin T, Huang Z, Zhang C, Shi M, Wu Y, Zheng W, Gao B, Xu K, Ye W
Antioxidants & redox signaling 2024 Aug;41(4-6):278-295
Antioxidants & redox signaling 2024 Aug;41(4-6):278-295
ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair.
Hua R, Zhao C, Xu Z, Liu D, Shen W, Yuan W, Li Y, Ma J, Wang Z, Feng S
Bioactive materials 2024 Aug;38:438-454
Bioactive materials 2024 Aug;38:438-454
Baicalin protects against hepatocyte injury caused by aflatoxin B(1) via the TP53-related ferroptosis Pathway.
Zhang HJ, Luo JZ, Lan CL, Teng X, Ge B, Liu JQ, Xie HX, Yang KJ, Qin CJ, Zhou X, Peng T
Ecotoxicology and environmental safety 2024 Aug;281:116661
Ecotoxicology and environmental safety 2024 Aug;281:116661
SLC7A11 and the glutathione pathway as novel prognostic markers in resectable pancreatic ductal adenocarcinoma: A metabolomics study of clinical specimens.
Ohya H, Miyake K, Fukuoka H, Oshi M, Ishibe A, Narita K, Kasahara K, Endo I
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2024 Aug;24(5):779-786
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2024 Aug;24(5):779-786
Nanoliposomes Encapsulated Rapamycin/Resveratrol to Induce Apoptosis and Ferroptosis for Enhanced Colorectal Cancer Therapy.
Jia M, Tan X, Yuan Z, Zhu W, Yan P
Journal of pharmaceutical sciences 2024 Aug;113(8):2565-2574
Journal of pharmaceutical sciences 2024 Aug;113(8):2565-2574
Effects on Iron Metabolism and System Xc- /GPX4 Pathway from Hydroquinone Suggest Ferroptosis of Jurkat Cells.
Liu N, Liu G, Li Q, Hu Y, Wang H
Toxics 2024 Aug 31;12(9)
Toxics 2024 Aug 31;12(9)
Natural Product Auraptene Targets SLC7A11 for Degradation and Induces Hepatocellular Carcinoma Ferroptosis.
Li D, Li Y, Chen L, Gao C, Dai B, Yu W, Yang H, Pi J, Bian X
Antioxidants (Basel, Switzerland) 2024 Aug 20;13(8)
Antioxidants (Basel, Switzerland) 2024 Aug 20;13(8)
PRMT5-mediated FUBP1 methylation accelerates prostate cancer progression.
Yan W, Liu X, Qiu X, Zhang X, Chen J, Xiao K, Wu P, Peng C, Hu X, Wang Z, Qin J, Sun L, Chen L, Wu D, Huang S, Yin L, Li Z
The Journal of clinical investigation 2024 Aug 15;134(18)
The Journal of clinical investigation 2024 Aug 15;134(18)
Biomineralization-Tuned Nanounits Reprogram the Signal Transducer and Activator of Transcription 3 Signaling for Ferroptosis-Immunotherapy in Cancer Stem Cells.
Zhao Y, Fei Y, Zhao Y, Li M, Hu Y, Cai K, Yu SH, Luo Z
ACS nano 2024 Aug 13;18(32):21268-21287
ACS nano 2024 Aug 13;18(32):21268-21287
Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway.
Kong L, Liu Y, Li J, Wang Y, Ji P, Shi Q, Han M, Xu H, Li W, Li W
Journal of ethnopharmacology 2024 Aug 10;330:118205
Journal of ethnopharmacology 2024 Aug 10;330:118205
Phosphoproteomics Reveals Novel Insights into the Pathogenesis and Identifies New Therapeutic Kinase Targets of Ulcerative Colitis.
Tao S, Long X, Gong P, Yu X, Tian L
Inflammatory bowel diseases 2024 Aug 1;30(8):1367-1378
Inflammatory bowel diseases 2024 Aug 1;30(8):1367-1378
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Li H, Wu D, Zhang H, Liu S, Zhen J, Yan Y, Li P
BMC gastroenterology 2024 Aug 1;24(1):245
BMC gastroenterology 2024 Aug 1;24(1):245
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53-P21/Nrf2 activation in a HuR-dependent m6A manner.
Yang Y, Ren J, Zhang J, Shi H, Wang J, Yan Y
Redox biology 2024 Apr;70:103067
Redox biology 2024 Apr;70:103067
SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization.
Deng J, Lin X, Qin J, Li Q, Zhang Y, Zhang Q, Ji C, Shen S, Li Y, Zhang B, Lin N
Redox biology 2024 Apr;70:103039
Redox biology 2024 Apr;70:103039
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
Lin H, Guo X, Liu J, Tang Y, Chen L, Chen H, Zhao Y, Wang L, Li H, Yu J, Yao P
Molecular nutrition & food research 2024 Apr;68(7):e2300343
Molecular nutrition & food research 2024 Apr;68(7):e2300343
Upregulation of UHRF1 Promotes PINK1-mediated Mitophagy to Alleviates Ferroptosis in Diabetic Nephropathy.
Ji H, Zhao Y, Ma X, Wu L, Guo F, Huang F, Song Y, Wang J, Qin G
Inflammation 2024 Apr;47(2):718-732
Inflammation 2024 Apr;47(2):718-732
Sulfasalazine promotes ferroptosis through AKT-ERK1/2 and P53-SLC7A11 in rheumatoid arthritis.
Zhao C, Yu Y, Yin G, Xu C, Wang J, Wang L, Zhao G, Ni S, Zhang H, Zhou B, Wang Y
Inflammopharmacology 2024 Apr;32(2):1277-1294
Inflammopharmacology 2024 Apr;32(2):1277-1294
APE1 inhibition enhances ferroptotic cell death and contributes to hepatocellular carcinoma therapy.
Du Y, Zhou Y, Yan X, Pan F, He L, Guo Z, Hu Z
Cell death and differentiation 2024 Apr;31(4):431-446
Cell death and differentiation 2024 Apr;31(4):431-446
A Pt(II) complex bearing N-heterocycle ring induced ferroptotic cell death in ovarian cancer.
Shen X, Peng Y, Zhou H, Ye X, Han Z, Shi X
Journal of inorganic biochemistry 2024 Apr;253:112502
Journal of inorganic biochemistry 2024 Apr;253:112502
Copper Exposure Induced Chicken Hepatotoxicity: Involvement of Ferroptosis Mediated by Lipid Peroxidation, Ferritinophagy, and Inhibition of FSP1-CoQ10 and Nrf2/SLC7A11/GPX4 Axis.
Zhong G, Li Y, Ma F, Huo Y, Liao J, Han Q, Hu L, Tang Z
Biological trace element research 2024 Apr;202(4):1711-1721
Biological trace element research 2024 Apr;202(4):1711-1721
PPARγ alleviates preeclampsia development by regulating lipid metabolism and ferroptosis.
Lai W, Yu L, Deng Y
Communications biology 2024 Apr 9;7(1):429
Communications biology 2024 Apr 9;7(1):429
L-cysteine contributes to destructive activities of odontogenic cysts/tumor.
Li J, Feng C, Pang X, Li X, Dou X, Jiang E, Shang Z
Discover oncology 2024 Apr 8;15(1):109
Discover oncology 2024 Apr 8;15(1):109
High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen.
Yang WP, Li MQ, Ding J, Li JY, Wu G, Liu B, Gao YQ, Wang GH, Luo QQ
eLife 2024 Apr 17;12
eLife 2024 Apr 17;12
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Bi R, Jiang L, Hu R, Wen B, Jiang Z, Liu H, Mei J
Heliyon 2024 Apr 15;10(7):e28093
Heliyon 2024 Apr 15;10(7):e28093
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression.
Qiao Y, Su M, Zhao H, Liu H, Wang C, Dai X, Liu L, Liu G, Sun H, Sun M, Wang J, Li Z, Fan J, Zhang Q, Li C, Situ F, Xue J, Jia Z, Zhang C, Zhang S, Shan C
Journal of experimental & clinical cancer research : CR 2024 Apr 10;43(1):108
Journal of experimental & clinical cancer research : CR 2024 Apr 10;43(1):108
A chemo/chemodynamic nanoparticle based on hyaluronic acid induces ferroptosis and apoptosis for triple-negative breast cancer therapy.
Wang N, Zhang Q, Wang Z, Liu Y, Yang S, Zhao X, Peng J
Carbohydrate polymers 2024 Apr 1;329:121795
Carbohydrate polymers 2024 Apr 1;329:121795
Quercetin Ameliorates Diabetic Kidney Injury by Inhibiting Ferroptosis via Activating Nrf2/HO-1 Signaling Pathway.
Feng Q, Yang Y, Qiao Y, Zheng Y, Yu X, Liu F, Wang H, Zheng B, Pan S, Ren K, Liu D, Liu Z
The American journal of Chinese medicine 2023;51(4):997-1018
The American journal of Chinese medicine 2023;51(4):997-1018
Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease.
Pan W, Xiang L, Liang X, Du W, Zhao J, Zhang S, Zhou X, Geng L, Gong S, Xu W
Mediators of inflammation 2023;2023:6623329
Mediators of inflammation 2023;2023:6623329
Vitamin D Promotes Ferroptosis in Colorectal Cancer Stem Cells via SLC7A11 Downregulation.
Guo S, Zhao W, Zhang W, Li S, Teng G, Liu L
Oxidative medicine and cellular longevity 2023;2023:4772134
Oxidative medicine and cellular longevity 2023;2023:4772134
Loss of Lactate/Proton Monocarboxylate Transporter 4 Induces Ferroptosis via the AMPK/ACC Pathway and Inhibition of Autophagy on Human Bladder Cancer 5637 Cell Line.
Dong S, Zheng L, Jiang T
Journal of oncology 2023;2023:2830306
Journal of oncology 2023;2023:2830306
Long Noncoding RNA LINC00578 Inhibits Ferroptosis in Pancreatic Cancer via Regulating SLC7A11 Ubiquitination.
Li H, Wei Y, Wang J, Yao J, Zhang C, Yu C, Tang Y, Zhu D, Yang J, Zhou J
Oxidative medicine and cellular longevity 2023;2023:1744102
Oxidative medicine and cellular longevity 2023;2023:1744102
miR-432-5p Inhibits the Ferroptosis in Cardiomyocytes Induced by Hypoxia/Reoxygenation via Activating Nrf2/SLC7A11 Axis by Degrading Keap1.
Geng W, Yan S, Li X, Liu Q, Zhang X, Gu X, Tian X, Jiang Y
Analytical cellular pathology (Amsterdam) 2023;2023:1293200
Analytical cellular pathology (Amsterdam) 2023;2023:1293200
GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver Failure.
Tao J, Xue C, Wang X, Chen H, Liu Q, Jiang C, Zhang W
International journal of medical sciences 2023;20(12):1616-1630
International journal of medical sciences 2023;20(12):1616-1630
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Cheng Z, Zhang X, Chen P, Wang H, Wang K, Shen Y
Open life sciences 2023;18(1):20220781
Open life sciences 2023;18(1):20220781
Vancomycin Induced Ferroptosis in Renal Injury Through the Inactivation of Recombinant Glutathione Peroxidase 4 and the Accumulation of Peroxides.
Yin X, Yang Q, Li H, Kang Y, Li Z
Drug design, development and therapy 2023;17:283-295
Drug design, development and therapy 2023;17:283-295
Physiological ischemic training improves cardiac function through the attenuation of cardiomyocyte apoptosis and the activation of the vagus nerve in chronic heart failure.
Zhu X, Wang S, Cheng Y, Gu H, Zhang X, Teng M, Zhang Y, Wang J, Hua W, Lu X
Frontiers in neuroscience 2023;17:1174455
Frontiers in neuroscience 2023;17:1174455
Solute Carrier Family 7 Member 11 (SLC7A11) is a Potential Prognostic Biomarker in Uterine Corpus Endometrial Carcinoma.
Fang X, Zhang T, Chen Z
International journal of general medicine 2023;16:481-497
International journal of general medicine 2023;16:481-497
AhR Promotes the Development of Non-small cell lung cancer by Inducing SLC7A11-dependent Antioxidant Function.
Peng Y, Ouyang L, Zhou Y, Lai W, Chen Y, Wang Z, Yan B, Zhang Z, Zhou Y, Peng X, Chen J, Peng X, Xiao D, Liu S, Tao Y, Liu W
Journal of Cancer 2023;14(5):821-834
Journal of Cancer 2023;14(5):821-834
Xue-Jie-San restricts ferroptosis in Crohn's disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop.
Gao Y, Zhang Z, Du J, Yang X, Wang X, Wen K, Sun X
Frontiers in pharmacology 2023;14:1148770
Frontiers in pharmacology 2023;14:1148770
Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis.
Liu X, Peng X, Cen S, Yang C, Ma Z, Shi X
Frontiers in pharmacology 2023;14:1129662
Frontiers in pharmacology 2023;14:1129662
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway.
Lou L, Wang M, He J, Yang S, Meng F, Wang S, Jin X, Cai J, Cai C
Frontiers in pharmacology 2023;14:1067402
Frontiers in pharmacology 2023;14:1067402
Bone marrow mesenchymal stem cell-derived exosomes protect podocytes from HBx-induced ferroptosis.
Yang X, Yu Y, Li B, Chen Y, Feng M, Hu Y, Jiang W
PeerJ 2023;11:e15314
PeerJ 2023;11:e15314
Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression.
He Y, Ling Y, Zhang Z, Mertens RT, Cao Q, Xu X, Guo K, Shi Q, Zhang X, Huo L, Wang K, Guo H, Shen W, Shen M, Feng W, Xiao P
Redox biology 2023 Sep;65:102822
Redox biology 2023 Sep;65:102822
Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel.
Dai X, Zhang J, Bao X, Guo Y, Jin Y, Yang C, Zhang H, Liu L, Gao Y, Ye C, Wu W, Liu C, Zhao CX, Sheng J, Ren E, Li H, Fang W, Wu B, Ruan J, Gu Z, Chen D, Zhao P
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2303542
Advanced materials (Deerfield Beach, Fla.) 2023 Sep;35(35):e2303542
Sulforaphane, an NRF2 agonist, alleviates ferroptosis in acute liver failure by regulating HDAC6 activity.
Zhang YQ, Shi CX, Zhang DM, Zhang LY, Wang LW, Gong ZJ
Journal of integrative medicine 2023 Sep;21(5):464-473
Journal of integrative medicine 2023 Sep;21(5):464-473
Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis.
He Y, Xi J, Fang J, Zhang B, Cai W
Free radical biology & medicine 2023 Sep;206:13-21
Free radical biology & medicine 2023 Sep;206:13-21
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway.
Feng S, Li Y, Huang H, Huang H, Duan Y, Yuan Z, Zhu W, Mei Z, Luo L, Yan P
European journal of pharmacology 2023 Sep 5;954:175853
European journal of pharmacology 2023 Sep 5;954:175853
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway.
Liu Z, Wang X, Li J, Yang X, Huang J, Ji C, Li X, Li L, Zhou J, Hu Y
Chemico-biological interactions 2023 Sep 1;382:110602
Chemico-biological interactions 2023 Sep 1;382:110602
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
Paraquat-induced ferroptosis suppression via NRF2 expression regulation.
Cai Q, Shen Q, Zhu W, Zhang S, Ke J, Lu Z
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105655
Toxicology in vitro : an international journal published in association with BIBRA 2023 Oct;92:105655
CAPG interference induces apoptosis and ferroptosis in colorectal cancer cells through the P53 pathway.
Zhao Y, Ma R, Wang C, Hu R, Wu W, Sun X, Chen B, Zhang W, Chen Y, Zhou J, Yuan P
Molecular and cellular probes 2023 Oct;71:101919
Molecular and cellular probes 2023 Oct;71:101919
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
Zhang L, Luo Y, Lv L, Chen S, Liu G, Zhao T
Cell death and differentiation 2023 Oct;30(10):2336-2350
Cell death and differentiation 2023 Oct;30(10):2336-2350
3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis.
Mu M, Zhang Q, Zhao C, Li X, Chen Z, Sun X, Yu J
Cancer gene therapy 2023 Oct;30(10):1414-1425
Cancer gene therapy 2023 Oct;30(10):1414-1425
Celastrol alleviated acute kidney injury by inhibition of ferroptosis through Nrf2/GPX4 pathway.
Pan M, Wang Z, Wang Y, Jiang X, Fan Y, Gong F, Sun Y, Wang D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115333
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115333
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
Ding Z, Pan Y, Shang T, Jiang T, Lin Y, Yang C, Pang S, Cui X, Wang Y, Feng XF, Xu M, Pei M, Chen Y, Li X, Ding J, Tan Y, Wang H, Dong L, Wang L
Nature communications 2023 Oct 7;14(1):6269
Nature communications 2023 Oct 7;14(1):6269
The clinical predictive value and regulation mechanism of microRNA-188-5p in contrast-induced acute kidney injury.
Yu R, Wu C, Xiao Y, Li Q, Chen J, Song J, Chen H, Wang Z, Wang W
Biochemical and biophysical research communications 2023 Oct 30;679:215-223
Biochemical and biophysical research communications 2023 Oct 30;679:215-223
2, 2-dimethylthiazolidine hydrochloride protects against experimental contrast-induced acute kidney injury via inhibition of tubular ferroptosis.
Dai B, Su Q, Liu X, Mi X, Dou L, Zhou D, Su Y, Shen T, Zhang Y, Xu W, Tan X, Wang D
Biochemical and biophysical research communications 2023 Oct 30;679:15-22
Biochemical and biophysical research communications 2023 Oct 30;679:15-22
Exogenous H(2)S initiating Nrf2/GPx4/GSH pathway through promoting Syvn1-Keap1 interaction in diabetic hearts.
Wang M, Tang J, Zhang S, Pang K, Zhao Y, Liu N, Huang J, Kang J, Dong S, Li H, Tian Z, Duan B, Lu F, Zhang W
Cell death discovery 2023 Oct 24;9(1):394
Cell death discovery 2023 Oct 24;9(1):394
Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis.
Liu Y, Cui H, Mei C, Cui M, He Q, Wang Q, Li D, Song Y, Li J, Chen S, Zhu C
Cell death & disease 2023 Oct 21;14(10):694
Cell death & disease 2023 Oct 21;14(10):694
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
Gao M, Lai K, Deng Y, Lu Z, Song C, Wang W, Xu C, Li N, Geng Q
Aging 2023 Oct 2;15(19):10089-10104
Aging 2023 Oct 2;15(19):10089-10104
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Wu Q, Liang Z, Jiang J, Feng X, Liu J, Zhang Z, Wang H, Wang N, Gou Y, Li Z, Cao Y
Cell death & disease 2023 Oct 11;14(10):668
Cell death & disease 2023 Oct 11;14(10):668
IRF1 suppresses colon cancer proliferation by reducing SPI1-mediated transcriptional activation of GPX4 and promoting ferroptosis.
Chen Y, Lin B, Yang S, Huang J
Experimental cell research 2023 Oct 1;431(1):113733
Experimental cell research 2023 Oct 1;431(1):113733
Ferroptosis contributes to cyclophosphamide-induced hemorrhagic cystitis.
Mao Z, Zhong K, Liu X, Zeng X
Chemico-biological interactions 2023 Oct 1;384:110701
Chemico-biological interactions 2023 Oct 1;384:110701
Qi-Shen-Tang alleviates retinitis pigmentosa by inhibiting ferroptotic features via the NRF2/GPX4 signaling pathway.
Xiong M, Ou C, Yu C, Qiu J, Lu J, Fu C, Peng Q, Zeng M, Song H
Heliyon 2023 Nov;9(11):e22443
Heliyon 2023 Nov;9(11):e22443
Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells.
Xia W, Zhu Z, Xiang S, Yang Y
Journal of ginseng research 2023 Nov;47(6):784-794
Journal of ginseng research 2023 Nov;47(6):784-794
Inhibition of ferroptosis alleviates chronic unpredictable mild stress-induced depression in mice via tsRNA-3029b.
Li E, Yin H, Su M, Li Q, Zhao Y, Zhang L, Guo J, Lai X, Xue X, Tang C
Brain research bulletin 2023 Nov;204:110773
Brain research bulletin 2023 Nov;204:110773
Drug Repurposing-Based Brain-Targeting Self-Assembly Nanoplatform Using Enhanced Ferroptosis against Glioblastoma.
Liang J, Li L, Tian H, Wang Z, Liu G, Duan X, Guo M, Liu J, Zhang W, Nice EC, Huang C, He W, Zhang H, Li Q
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(46):e2303073
Small (Weinheim an der Bergstrasse, Germany) 2023 Nov;19(46):e2303073
Brusatol induces ferroptosis in oesophageal squamous cell carcinoma by repressing GSH synthesis and increasing the labile iron pool via inhibition of the NRF2 pathway.
Zhu X, Huang N, Ji Y, Sheng X, Huo J, Zhu Y, Huang M, He W, Ma J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115567
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115567
Fructus Lycii and Salvia miltiorrhiza Bunge extract attenuate oxidative stress-induced photoreceptor ferroptosis in retinitis pigmentosa.
Yang Y, Wang Y, Deng Y, Lu J, Xiao L, Li J, Zhou Y, Nie F, Chen X, Peng J, Tan H, Qin Y, Peng Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Nov;167:115547
Identification of disulfidptosis-related subtypes and development of a prognosis model based on stacking framework in renal clear cell carcinoma.
Peng K, Wang N, Liu Q, Wang L, Duan X, Xie G, Li J, Ding D
Journal of cancer research and clinical oncology 2023 Nov;149(15):13793-13810
Journal of cancer research and clinical oncology 2023 Nov;149(15):13793-13810
Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(33):e2302953
Inhibition of Ferroptosis Ameliorates Photoreceptor Degeneration in Experimental Diabetic Mice.
Gao S, Gao S, Wang Y, Li N, Yang Z, Yao H, Chen Y, Cheng Y, Zhong Y, Shen X
International journal of molecular sciences 2023 Nov 29;24(23)
International journal of molecular sciences 2023 Nov 29;24(23)
METTL9-SLC7A11 axis promotes hepatocellular carcinoma progression through ferroptosis inhibition.
Bi F, Qiu Y, Wu Z, Liu S, Zuo D, Huang Z, Li B, Yuan Y, Niu Y, Qiu J
Cell death discovery 2023 Nov 28;9(1):428
Cell death discovery 2023 Nov 28;9(1):428
Vitamin D Attenuates Ulcerative Colitis by Inhibiting ACSL4-Mediated Ferroptosis.
Gao S, Sun C, Kong J
Nutrients 2023 Nov 20;15(22)
Nutrients 2023 Nov 20;15(22)
Activation of the Nrf-2 pathway by pinocembrin safeguards vertebral endplate chondrocytes against apoptosis and degeneration caused by oxidative stress.
Wang H, Liu X, Yang H, Jing X, Wang W, Liu X, Zhang B, Liu X, Shao Y, Cui X
Life sciences 2023 Nov 15;333:122162
Life sciences 2023 Nov 15;333:122162
Hydrogen sulfide ameliorates endothelial dysfunction in aging arteries by regulating ferroptosis.
Miao Y, Zhang S, Liang Z, Wang Y, Tian D, Jin S, Guo Q, Xue H, Teng X, Xiao L, Wu Y
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Nitric oxide : biology and chemistry 2023 Nov 1;140-141:77-90
Synergistic ferroptosis-starvation therapy for bladder cancer based on hyaluronic acid modified metal-organic frameworks.
Wang Y, Xie K, Chen W, Fang Y, Mo Q, Zhang H, Zhao X, Li D, Tan W, Zhao P, Li F
Bioengineering & translational medicine 2023 May;8(3):e10515
Bioengineering & translational medicine 2023 May;8(3):e10515
Metabolomics analysis reveals cytotoxic effects of ouabain towards psoriatic keratinocytes via impairment of glutathione metabolism.
Zhou X, Fei F, Song W, Ma H, Xu Z, Yue J, Cao B, Sun R, Zhao Y, Yang Y, Jiang J, Geng Y, Weng Z, Li J
Molecular genetics and genomics : MGG 2023 May;298(3):567-577
Molecular genetics and genomics : MGG 2023 May;298(3):567-577
p53 Activates the Lipoxygenase Activity of ALOX15B via Inhibiting SLC7A11 to Induce Ferroptosis in Bladder Cancer Cells.
Li X, Xiong W, Wang Y, Li Y, Cheng X, Liu W
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100058
Laboratory investigation; a journal of technical methods and pathology 2023 May;103(5):100058
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J
Carcinogenesis 2023 May 26;44(2):129-142
Carcinogenesis 2023 May 26;44(2):129-142
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
QiShenYiQi dripping pill alleviates myocardial ischemia-induced ferroptosis via improving mitochondrial dynamical homeostasis and biogenesis.
Wu L, Fan Z, Gu L, Liu J, Cui Z, Yu B, Kou J, Li F
Journal of ethnopharmacology 2023 May 23;308:116282
Journal of ethnopharmacology 2023 May 23;308:116282
Engineering MMP-2 Activated Nanoparticles Carrying B7-H3 Bispecific Antibodies for Ferroptosis-Enhanced Glioblastoma Immunotherapy.
Fan R, Chen C, Mu M, Chuan D, Liu H, Hou H, Huang J, Tong A, Guo G, Xu J
ACS nano 2023 May 23;17(10):9126-9139
ACS nano 2023 May 23;17(10):9126-9139
Liberation of daidzein by gut microbial β-galactosidase suppresses acetaminophen-induced hepatotoxicity in mice.
Zeng Y, Wu R, Wang F, Li S, Li L, Li Y, Qin P, Wei M, Yang J, Wu J, Chen A, Ke G, Yan Z, Yang H, Chen Z, Wang Z, Xiao W, Jiang Y, Chen X, Zeng Z, Zhao X, Chen P, Gong S
Cell host & microbe 2023 May 10;31(5):766-780.e7
Cell host & microbe 2023 May 10;31(5):766-780.e7
Hepatocyte ferroptosis contributes to anti-tuberculosis drug-induced liver injury: Involvement of the HIF-1α/SLC7A11/GPx4 axis.
Liu Y, Chen W, Cen Y, Zhao X, Chen Z, Liang Y, Huang Z, He X, Yang G
Chemico-biological interactions 2023 May 1;376:110439
Chemico-biological interactions 2023 May 1;376:110439
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
Zhao J, Yang S, Lv C, Liu Y
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052
American journal of physiology. Cell physiology 2023 May 1;324(5):C1039-C1052
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
Xu W, Ding J, Li B, Sun T, You X, He Q, Sheng W
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
BioFactors (Oxford, England) 2023 Mar;49(2):438-456
Identification of a ferroptosis-related gene signature for prognosis prediction in colorectal cancer patients and relationship with vitamin D.
Guo S, Zhao W, Zhang T, Li S, Guo J, Liu L
The Journal of steroid biochemistry and molecular biology 2023 Mar;227:106234
The Journal of steroid biochemistry and molecular biology 2023 Mar;227:106234
FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3.
Jiang H, Fang Y, Wang Y, Li T, Lin H, Lin J, Pan T, Liu Q, Lv J, Chen D, Chen Y
International immunopharmacology 2023 Mar;116:109762
International immunopharmacology 2023 Mar;116:109762
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
Lai K, Song C, Gao M, Deng Y, Lu Z, Li N, Geng Q
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Wang Q, Ke S, Liu Z, Shao H, He M, Guo J
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
Cai J, Ye Z, Hu Y, Ye L, Gao L, Wang Y, Sun Q, Tong S, Zhang S, Wu L, Yang J, Chen Q
Cell death & disease 2023 Mar 25;14(3):211
Cell death & disease 2023 Mar 25;14(3):211
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Cui X, Liu X, Kong P, Du T, Li T, Yang G, Zhang W, Jing X, Wang W
Aging 2023 Mar 24;15(6):2275-2292
Aging 2023 Mar 24;15(6):2275-2292
Mechanism of ferroptosis in a rat model of premature ovarian insufficiency induced by cisplatin.
Du R, Cheng X, Ji J, Lu Y, Xie Y, Wang W, Xu Y, Zhang Y
Scientific reports 2023 Mar 17;13(1):4463
Scientific reports 2023 Mar 17;13(1):4463
Inhibiting NLRP3 Inflammasome Activation by CY-09 Helps to Restore Cerebral Glucose Metabolism in 3×Tg-AD Mice.
Han S, He Z, Hu X, Li X, Zheng K, Huang Y, Xiao P, Xie Q, Ni J, Liu Q
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
Antioxidants (Basel, Switzerland) 2023 Mar 15;12(3)
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma.
Kang L, Wang D, Shen T, Liu X, Dai B, Zhou D, Shen H, Gong J, Li G, Hu Y, Wang P, Mi X, Zhang Y, Tan X
Cell death & disease 2023 Mar 11;14(3):193
Cell death & disease 2023 Mar 11;14(3):193
UTP11 deficiency suppresses cancer development via nucleolar stress and ferroptosis.
Gan Y, Deng J, Hao Q, Huang Y, Han T, Xu JG, Zhao M, Yao L, Xu Y, Xiong J, Lu H, Wang C, Chen J, Zhou X
Redox biology 2023 Jun;62:102705
Redox biology 2023 Jun;62:102705
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
Yao B, Cai Y, Wan L, Deng J, Zhao L, Wang W, Han Z
The journal of gene medicine 2023 Jun;25(6):e3488
The journal of gene medicine 2023 Jun;25(6):e3488
Mesenchymal stem cell-derived exosomal microRNA-367-3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2.
Fan J, Han Y, Sun H, Sun S, Wang Y, Guo R, Guo J, Tian X, Wang J, Wang J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114593
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114593
Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.
Shi Z, Li Z, Jin B, Ye W, Wang L, Zhang S, Zheng J, Lin Z, Chen B, Liu F, Zhang B, Ding X, Yang Z, Shan Y, Yu Z, Wang Y, Chen J, Chen Q, Roberts LR, Chen G
Clinical and translational medicine 2023 Jun;13(6):e1300
Clinical and translational medicine 2023 Jun;13(6):e1300
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
Yang G, Liu X, Jing X, Wang J, Wang H, Chen F, Wang W, Shao Y, Cui X
International immunopharmacology 2023 Jun;119:110159
International immunopharmacology 2023 Jun;119:110159
PRMT5 reduces immunotherapy efficacy in triple-negative breast cancer by methylating KEAP1 and inhibiting ferroptosis.
Wang Z, Li R, Hou N, Zhang J, Wang T, Fan P, Ji C, Zhang B, Liu L, Wang Y, Kong J, Yao Q, Duan J, Zhao G, Ling R, Zhang J
Journal for immunotherapy of cancer 2023 Jun;11(6)
Journal for immunotherapy of cancer 2023 Jun;11(6)
Terpinen-4-ol Induces Ferroptosis of Glioma Cells via Downregulating JUN Proto-Oncogene.
Cao W, Li Y, Zeng Z, Lei S
Molecules (Basel, Switzerland) 2023 Jun 8;28(12)
Molecules (Basel, Switzerland) 2023 Jun 8;28(12)
Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer.
Wu W, Zhao Y, Qin B, Jiang X, Wang C, Hu R, Ma R, Lee MH, Liu H, Li K, Yuan P
EBioMedicine 2023 Jul;93:104650
EBioMedicine 2023 Jul;93:104650
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Graphdiyne nanoplatforms for photothermal-ferroptosis combination therapy against glioblastoma.
Zhao LX, Gong ZQ, Zhang Q, He DL, Ge RL, Meng J, Ren H, Fan YG, Wang ZY
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:12-25
Journal of controlled release : official journal of the Controlled Release Society 2023 Jul;359:12-25
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
Artemisia argyi H.Lév. & Vaniot essential oil induces ferroptosis in pancreatic cancer cells via up-regulation of TFR1 and depletion of γ-glutamyl cycle.
Zhang N, Zhang J, Cui W, Wu D, Zhang J, Wei B, Qu L, Xu X
Fitoterapia 2023 Jul;168:105522
Fitoterapia 2023 Jul;168:105522
Cisatracurium besylate rescues Mycobacterium Tuberculosis-infected macrophages from necroptosis and enhances the bactericidal effect of isoniazid.
Wen Q, Zhang J, Zhang Z, Chen L, Liu H, Han Z, Chen Y, Wang K, Liu J, Sai N, Zhou X, Zhou C, Hu S, Ma L
International immunopharmacology 2023 Jul;120:110291
International immunopharmacology 2023 Jul;120:110291
Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway.
Jiang YQ, Yang XY, Duan DQ, Zhang YY, Li NS, Tang LJ, Peng J, Luo XJ
European journal of pharmacology 2023 Jul 5;950:175774
European journal of pharmacology 2023 Jul 5;950:175774
The effect of ferroptosis - related proteins and histone deacetylases1 on neoadjuvant chemotherapy in breast cancer.
Sun H, Lin Y, Liu J, Zheng X, Wang Y, Cai J, Wei X
Medicine 2023 Jul 28;102(30):e34444
Medicine 2023 Jul 28;102(30):e34444
Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons.
Mun SH, Lee CS, Kim HJ, Kim J, Lee H, Yang J, Im SH, Kim JH, Seong JK, Hwang CS
Cell reports 2023 Jul 25;42(7):112746
Cell reports 2023 Jul 25;42(7):112746
Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis.
Wen RJ, Dong X, Zhuang HW, Pang FX, Ding SC, Li N, Mai YX, Zhou ST, Wang JY, Zhang JF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154881
Medroxyprogesterone acetate-resistant endometrial cancer cells are susceptible to ferroptosis inducers.
Murakami H, Hayashi M, Terada S, Ohmichi M
Life sciences 2023 Jul 15;325:121753
Life sciences 2023 Jul 15;325:121753
m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis.
Huang WM, Li ZX, Wu YH, Shi ZL, Mi JL, Hu K, Wang RS
Translational oncology 2023 Jan;27:101576
Translational oncology 2023 Jan;27:101576
A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis.
Fan J, Xu X, Li Y, Zhang L, Miao M, Niu Y, Zhang Y, Zhang A, Jia Z, Wu M
Free radical biology & medicine 2023 Jan;194:84-98
Free radical biology & medicine 2023 Jan;194:84-98
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.
Barayeu U, Schilling D, Eid M, Xavier da Silva TN, Schlicker L, Mitreska N, Zapp C, Gräter F, Miller AK, Kappl R, Schulze A, Friedmann Angeli JP, Dick TP
Nature chemical biology 2023 Jan;19(1):28-37
Nature chemical biology 2023 Jan;19(1):28-37
DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson's disease.
Hu CB, Jiang H, Yang Y, Wang GH, Ji QH, Jia ZZ, Shen LH, Luo QQ
Neural regeneration research 2023 Jan;18(1):194-199
Neural regeneration research 2023 Jan;18(1):194-199
Treatment with paraquat affects the expression of ferroptosis-related genes.
Ge X, Cai Q, Zhang S, Wu X, Ying P, Ke J, Yang Z
Human & experimental toxicology 2023 Jan-Dec;42:9603271231167585
Human & experimental toxicology 2023 Jan-Dec;42:9603271231167585
Sodium Butyrate Induces CRC Cell Ferroptosis via the CD44/SLC7A11 Pathway and Exhibits a Synergistic Therapeutic Effect with Erastin.
Bian Z, Sun X, Liu L, Qin Y, Zhang Q, Liu H, Mao L, Sun S
Cancers 2023 Jan 9;15(2)
Cancers 2023 Jan 9;15(2)
Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells.
Hsu DJ, Gao J, Yamaguchi N, Pinzaru A, Wu Q, Mandayam N, Liberti M, Heissel S, Alwaseem H, Tavazoie S, Tavazoie SF
Science advances 2023 Jan 6;9(1):eade9120
Science advances 2023 Jan 6;9(1):eade9120
MFG-E8 stabilized by deubiquitinase USP14 suppresses cigarette smoke-induced ferroptosis in bronchial epithelial cells.
Cui Y, Luo L, Zeng Z, Liu X, Li T, He X, Ma Y, Meng W, Zeng H, Long Y, Zong D, Chen Y
Cell death & disease 2023 Jan 3;14(1):2
Cell death & disease 2023 Jan 3;14(1):2
Organic extracts in PM2.5 are the major triggers to induce ferroptosis in SH-SY5Y cells.
Guo C, Lyu Y, Xia S, Ren X, Li Z, Tian F, Zheng J
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
Ecotoxicology and environmental safety 2023 Jan 1;249:114350
pH-sensitive molybdenum (Mo)-based polyoxometalate nanoclusters have therapeutic efficacy in inflammatory bowel disease by counteracting ferroptosis.
Yang F, Chen Y, Xiao Y, Jiang H, Jiang Z, Yang M, Li M, Su Y, Yan Z, Lin Y, Li D
Pharmacological research 2023 Feb;188:106645
Pharmacological research 2023 Feb;188:106645
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Tan XH, Gu YY, Song WP, Nan TG, Song WD, Fang D, Yuan YM, Xin ZC, Li XS, Guan RL
Sexual medicine 2023 Feb;11(1):qfac008
Sexual medicine 2023 Feb;11(1):qfac008
Feasibility of [(18)F]FSPG PET for Early Response Assessment to Combined Blockade of EGFR and Glutamine Metabolism in Wild-Type KRAS Colorectal Cancer.
Bae SW, Wang J, Georgiou DK, Wen X, Cohen AS, Geng L, Tantawy MN, Manning HC
Tomography (Ann Arbor, Mich.) 2023 Feb 24;9(2):497-508
Tomography (Ann Arbor, Mich.) 2023 Feb 24;9(2):497-508
Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma.
Li X, Wang Q, Xu C, Zhang L, Zhou J, Lv J, Xu M, Jiang D
Cancers 2023 Feb 18;15(4)
Cancers 2023 Feb 18;15(4)
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway.
Lu Q, Yang L, Xiao JJ, Liu Q, Ni L, Hu JW, Yu H, Wu X, Zhang BF
Free radical biology & medicine 2023 Feb 1;195:89-102
Free radical biology & medicine 2023 Feb 1;195:89-102
Neurotoxic A1 astrocytes promote neuronal ferroptosis via CXCL10/CXCR3 axis in epilepsy.
Liang P, Zhang X, Zhang Y, Wu Y, Song Y, Wang X, Chen T, Liu W, Peng B, Yin J, He F, Fan Y, Han S, He X
Free radical biology & medicine 2023 Feb 1;195:329-342
Free radical biology & medicine 2023 Feb 1;195:329-342
The SIRT3 activator ganoderic acid D regulates airway mucin MUC5AC expression via the NRF2/GPX4 pathway.
Wang J, Li J, He Y, Huang X, Feng J, Liu L, Liu Y, Jiang X, Jia J
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
Pulmonary pharmacology & therapeutics 2023 Dec;83:102262
ATR-dependent ubiquitin-specific protease 20 phosphorylation confers oxaliplatin and ferroptosis resistance.
Tang J, Long G, Xiao D, Liu S, Xiao L, Zhou L, Tao Y
MedComm 2023 Dec;4(6):e463
MedComm 2023 Dec;4(6):e463
Curcumin strengthens a spontaneous self-protective mechanism-SP1/PRDX6 pathway, against di-n-butyl phthalate-induced testicular ferroptosis damage.
Bu H, Wang B, Wu Y, Li P, Cui Y, Jiang X, Yu X, Liu B, Tang M
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Environmental science and pollution research international 2023 Dec;30(58):122165-122181
Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway.
Dong X, Xu L, Wang S, Jiao X, Yan S, Huang Y, Yuan M, Wang G
Molecular human reproduction 2023 Dec 24;30(1)
Molecular human reproduction 2023 Dec 24;30(1)
TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Yang R, Wan J, Ma L, Zhou F, Yang Z, Li Z, Zhang M, Ming L
Cell death discovery 2023 Dec 1;9(1):431
Cell death discovery 2023 Dec 1;9(1):431
The ubiquitin-specific protease 5 mediated deubiquitination of LSH links metabolic regulation of ferroptosis to hepatocellular carcinoma progression.
Yan B, Guo J, Wang Z, Ning J, Wang H, Shu L, Hu K, Chen L, Shi Y, Zhang L, Liu S, Tao Y, Xiao D
MedComm 2023 Aug;4(4):e337
MedComm 2023 Aug;4(4):e337
Effect of P53 nuclear localization mediated by G3BP1 on ferroptosis in acute liver failure.
Li W, Li W, Li X, Wang L, Wang Y
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1226-1240
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1226-1240
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Li C, He Z, Yao F, Liao S, Sun K, Sun S, Li Z, Wang Z
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
Apoptosis : an international journal on programmed cell death 2023 Aug;28(7-8):1154-1167
ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Lung 2023 Aug;201(4):425-441
Lung 2023 Aug;201(4):425-441
Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis.
Merkel M, Goebel B, Boll M, Adhikari A, Maurer V, Steinhilber D, Culmsee C
Antioxidants (Basel, Switzerland) 2023 Aug 9;12(8)
Antioxidants (Basel, Switzerland) 2023 Aug 9;12(8)
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids.
Wang X, Quan J, Xiu C, Wang J, Zhang J
Chinese medicine 2023 Aug 30;18(1):110
Chinese medicine 2023 Aug 30;18(1):110
Ficolin B secreted by alveolar macrophage exosomes exacerbates bleomycin-induced lung injury via ferroptosis through the cGAS-STING signaling pathway.
Wu X, Jiang Y, Li R, Xia Y, Li F, Zhao M, Li G, Tan X
Cell death & disease 2023 Aug 30;14(8):577
Cell death & disease 2023 Aug 30;14(8):577
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Inhibition of Connexin43 Improves the Recovery of Spinal Cord Injury Against Ferroptosis via the SLC7A11/GPX4 Pathway.
Huang Q, Sha W, Gu Q, Wang J, Zhu Y, Xu T, Xu Z, Yan F, Lin X, Tian S
Neuroscience 2023 Aug 21;526:121-134
Neuroscience 2023 Aug 21;526:121-134
A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Bow YD, Ko CC, Chang WT, Chou SY, Hung CT, Huang JL, Tseng CH, Chen YL, Li RN, Chiu CC
Cancer cell international 2023 Aug 16;23(1):171
Cancer cell international 2023 Aug 16;23(1):171
Targeting the Na(+)/K(+) ATPase DR-region with DR-Ab improves doxorubicin-induced cardiotoxicity.
Leng B, Deng L, Tan J, Lee WT, Cao CR, Wang ZP, Huang DJ, Nie X, Bian JS
Free radical biology & medicine 2023 Aug 1;204:38-53
Free radical biology & medicine 2023 Aug 1;204:38-53
Ketogenic diet alleviates brain iron deposition and cognitive dysfunction via Nrf2-mediated ferroptosis pathway in APP/PS1 mouse.
Qin Y, Bai D, Tang M, Zhang M, Zhao L, Li J, Yang R, Jiang G
Brain research 2023 Aug 1;1812:148404
Brain research 2023 Aug 1;1812:148404
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis.
Zhao W, Lei M, Li J, Zhang H, Zhang H, Han Y, Ba Z, Zhang M, Li D, Liu C
Heliyon 2023 Apr;9(4):e15075
Heliyon 2023 Apr;9(4):e15075
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Qi D, Chen P, Bao H, Zhang L, Sun K, Song S, Li T
Cell cycle (Georgetown, Tex.) 2023 Apr;22(7):818-828
Cell cycle (Georgetown, Tex.) 2023 Apr;22(7):818-828
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury.
Kang Y, Zhu R, Li S, Qin KP, Tang H, Shan WS, Yin ZS
Neural regeneration research 2023 Apr;18(4):881-888
Neural regeneration research 2023 Apr;18(4):881-888
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Gong Z, Wang Y, Li L, Li X, Qiu B, Hu Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Apr;174:113644
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
Single-cell transcriptomes reveal heterogeneity of chlorine-induced mice acute lung injury and the inhibitory effect of pentoxifylline on ferroptosis.
Zhao CQ, Wang C, Liu MM, Cao M, Peng J, Kong DQ, Ren XT, Liu R, Hai CX, Zhang XD
Scientific reports 2023 Apr 26;13(1):6833
Scientific reports 2023 Apr 26;13(1):6833
Glucose Starvation Inhibits Ferroptosis by Activating the LKB1/AMPK Signaling Pathway and Promotes the High Speed Linear Motility of Dairy Goat Sperm.
Li Y, Zhang G, Wen F, Xian M, Guo S, Zhang X, Feng X, Hu Z, Hu J
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
Animals : an open access journal from MDPI 2023 Apr 23;13(9)
Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway.
Chen L, Huang J, Yao ZM, Sun XR, Tong XH, Hu M, Zhang Y, Dong SY
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
Molecules (Basel, Switzerland) 2023 Apr 20;28(8)
Ginsenoside Rh3 induces pyroptosis and ferroptosis through the Stat3/p53/NRF2 axis in colorectal cancer cells.
Wu Y, Pi D, Zhou S, Yi Z, Dong Y, Wang W, Ye H, Chen Y, Zuo Q, Ouyang M
Acta biochimica et biophysica Sinica 2023 Apr 19;55(4):587-600
Acta biochimica et biophysica Sinica 2023 Apr 19;55(4):587-600
Hydrogen Sulfide Inhibits Ferroptosis in Cardiomyocytes to Protect Cardiac Function in Aging Rats.
Liang Z, Miao Y, Teng X, Xiao L, Guo Q, Xue H, Tian D, Jin S, Wu Y
Frontiers in molecular biosciences 2022;9:947778
Frontiers in molecular biosciences 2022;9:947778
Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide induces ferroptosis in neuroblastoma cells through redox imbalance.
Lyu Y, Ren XK, Guo CC, Li ZF, Zheng JP
The Journal of toxicological sciences 2022;47(12):519-529
The Journal of toxicological sciences 2022;47(12):519-529
High-Fat Diet Increases Bone Loss by Inducing Ferroptosis in Osteoblasts.
Zhu R, Wang Z, Xu Y, Wan H, Zhang X, Song M, Yang H, Chai Y, Yu B
Stem cells international 2022;2022:9359429
Stem cells international 2022;2022:9359429
Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage.
Yuan B, Zhao XD, Shen JD, Chen SJ, Huang HY, Zhou XM, Han YL, Zhou LJ, Lu XJ, Wu Q
Oxidative medicine and cellular longevity 2022;2022:9069825
Oxidative medicine and cellular longevity 2022;2022:9069825
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S, Liu H, Wang B
Oxidative medicine and cellular longevity 2022;2022:8287227
Oxidative medicine and cellular longevity 2022;2022:8287227
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Wu Y, Pi D, Chen Y, Zuo Q, Zhou S, Ouyang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y, Wang J, Wang X, Zhang J, Shao A
Oxidative medicine and cellular longevity 2022;2022:4295208
Oxidative medicine and cellular longevity 2022;2022:4295208
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
Cardiac Fibroblasts Promote Ferroptosis in Atrial Fibrillation by Secreting Exo-miR-23a-3p Targeting SLC7A11.
Liu D, Yang M, Yao Y, He S, Wang Y, Cao Z, Chen H, Fu Y, Liu H, Zhao Q
Oxidative medicine and cellular longevity 2022;2022:3961495
Oxidative medicine and cellular longevity 2022;2022:3961495
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Han S, Lin F, Qi Y, Liu C, Zhou L, Xia Y, Chen K, Xing J, Liu Z, Yu W, Zhang Y, Zhou X, Rao T, Cheng F
Oxidative medicine and cellular longevity 2022;2022:3846217
Oxidative medicine and cellular longevity 2022;2022:3846217
Theaflavin-3,3'-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis.
Xu C, Ni S, Xu N, Yin G, Yu Y, Zhou B, Zhao G, Wang L, Zhu R, Jiang S, Wang Y
Oxidative medicine and cellular longevity 2022;2022:3531995
Oxidative medicine and cellular longevity 2022;2022:3531995
Pan-Cancer Analyses Confirmed the Ferroptosis-Related Gene SLC7A11 as a Prognostic Biomarker for Cancer.
Lin Y, Dong Y, Liu W, Fan X, Sun Y
International journal of general medicine 2022;15:2501-2513
International journal of general medicine 2022;15:2501-2513
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Shao Y, Sun L, Yang G, Wang W, Liu X, Du T, Chen F, Jing X, Cui X
Frontiers in pharmacology 2022;13:937502
Frontiers in pharmacology 2022;13:937502
Ferrostatin-1 Ameliorates Liver Dysfunction via Reducing Iron in Thioacetamide-induced Acute Liver Injury in Mice.
Jiang H, Zhang X, Yang W, Li M, Wang G, Luo Q
Frontiers in pharmacology 2022;13:869794
Frontiers in pharmacology 2022;13:869794
Cyclophosphamide Induces the Ferroptosis of Tumor Cells Through Heme Oxygenase-1.
Shi H, Hou B, Li H, Zhou H, Du B
Frontiers in pharmacology 2022;13:839464
Frontiers in pharmacology 2022;13:839464
TFAP2C-Mediated lncRNA PCAT1 Inhibits Ferroptosis in Docetaxel-Resistant Prostate Cancer Through c-Myc/miR-25-3p/SLC7A11 Signaling.
Jiang X, Guo S, Xu M, Ma B, Liu R, Xu Y, Zhang Y
Frontiers in oncology 2022;12:862015
Frontiers in oncology 2022;12:862015
FNDC5 Causes Resistance to Sorafenib by Activating the PI3K/Akt/Nrf2 Pathway in Hepatocellular Carcinoma Cells.
Liu H, Zhao L, Wang M, Yang K, Jin Z, Zhao C, Shi G
Frontiers in oncology 2022;12:852095
Frontiers in oncology 2022;12:852095
Induction of Ferroptosis by Ophiopogonin-B Through Regulating the Gene Signature AURKA in NSCLC.
Li L, Gao Q, Wang J, Gu L, Li Z, Zhang S, Hu C, He M, Wang Y, Wang Z, Yi Y, Fu J, Zhang X, Ge F, Chen M, Zhang X
Frontiers in oncology 2022;12:833814
Frontiers in oncology 2022;12:833814
PLA2G6 Silencing Suppresses Melanoma Progression and Affects Ferroptosis Revealed by Quantitative Proteomics.
Wang Y, Song H, Miao Q, Wang Y, Qi J, Xu X, Sun J
Frontiers in oncology 2022;12:819235
Frontiers in oncology 2022;12:819235
Overexpression of LINC00551 promotes autophagy-dependent ferroptosis of lung adenocarcinoma via upregulating DDIT4 by sponging miR-4328.
Peng X, Yang R, Peng W, Zhao Z, Tu G, He B, Cai Q, Shi S, Yin W, Yu F, Tao Y, Wang X
PeerJ 2022;10:e14180
PeerJ 2022;10:e14180
ARPC1A is regulated by STAT3 to inhibit ferroptosis and promote prostate cancer progression.
Ji J, Li H, Wang W, Yuan B, Shen T
Human cell 2022 Sep;35(5):1591-1601
Human cell 2022 Sep;35(5):1591-1601
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Li J, Tang X, Tu X, Jin Z, Dong H, Yang Q, Yao T, Pan Z
Cell stress & chaperones 2022 Sep;27(5):485-497
Cell stress & chaperones 2022 Sep;27(5):485-497
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Wang W, Jing X, Du T, Ren J, Liu X, Chen F, Shao Y, Sun S, Yang G, Cui X
Free radical biology & medicine 2022 Sep;190:234-246
Free radical biology & medicine 2022 Sep;190:234-246
Astaxanthin Activated the Nrf2/HO-1 Pathway to Enhance Autophagy and Inhibit Ferroptosis, Ameliorating Acetaminophen-Induced Liver Injury.
Cai X, Hua S, Deng J, Du Z, Zhang D, Liu Z, Khan NU, Zhou M, Chen Z
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
ACS applied materials & interfaces 2022 Sep 28;14(38):42887-42903
IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis.
Li B, Wang C, Lu P, Ji Y, Wang X, Liu C, Lu X, Xu X, Wang X
Biology 2022 Sep 23;11(10)
Biology 2022 Sep 23;11(10)
FTH1- and SAT1-Induced Astrocytic Ferroptosis Is Involved in Alzheimer's Disease: Evidence from Single-Cell Transcriptomic Analysis.
Dang Y, He Q, Yang S, Sun H, Liu Y, Li W, Tang Y, Zheng Y, Wu T
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Pharmaceuticals (Basel, Switzerland) 2022 Sep 22;15(10)
Targeting NRF2 Sensitizes Esophageal Adenocarcinoma Cells to Cisplatin through Induction of Ferroptosis and Apoptosis.
Ballout F, Lu H, Chen Z, Hu T, Chen L, Washington MK, El-Rifai W, Peng D
Antioxidants (Basel, Switzerland) 2022 Sep 21;11(10)
Antioxidants (Basel, Switzerland) 2022 Sep 21;11(10)
1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.
Guan S, Zhang R, Zhao Y, Meng Z, Lu J
Environmental toxicology 2022 Oct;37(10):2515-2528
Environmental toxicology 2022 Oct;37(10):2515-2528
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Wang Z, Yao M, Jiang L, Wang L, Yang Y, Wang Q, Qian X, Zhao Y, Qian J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113572
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113572
Circulating small extracellular vesicle-encapsulated SEMA5A-IT1 attenuates myocardial ischemia-reperfusion injury after cardiac surgery with cardiopulmonary bypass.
Wu T, Shi G, Ji Z, Wang S, Geng L, Guo Z
Cellular & molecular biology letters 2022 Oct 25;27(1):95
Cellular & molecular biology letters 2022 Oct 25;27(1):95
Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway.
Li J, Wang X, Zhou R, Cheng F, Tang X, Lao J, Xu L, He W, Wan D, Zeng H, Zhang S
Molecules (Basel, Switzerland) 2022 Oct 20;27(20)
Molecules (Basel, Switzerland) 2022 Oct 20;27(20)
Matrix stiffness-dependent STEAP3 coordinated with PD-L2 identify tumor responding to sorafenib treatment in hepatocellular carcinoma.
Wang S, Chen L, Liu W
Cancer cell international 2022 Oct 13;22(1):318
Cancer cell international 2022 Oct 13;22(1):318
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Zhao Y, Zhang R, Wang Z, Chen Z, Wang G, Guan S, Lu J
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
Iron overload-induced ferroptosis of osteoblasts inhibits osteogenesis and promotes osteoporosis: An in vitro and in vivo study.
Jiang Z, Wang H, Qi G, Jiang C, Chen K, Yan Z
IUBMB life 2022 Nov;74(11):1052-1069
IUBMB life 2022 Nov;74(11):1052-1069
SHARPIN promotes cell proliferation of cholangiocarcinoma and inhibits ferroptosis via p53/SLC7A11/GPX4 signaling.
Zeng C, Lin J, Zhang K, Ou H, Shen K, Liu Q, Wei Z, Dong X, Zeng X, Zeng L, Wang W, Yao J
Cancer science 2022 Nov;113(11):3766-3775
Cancer science 2022 Nov;113(11):3766-3775
PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma.
Hu X, He Y, Han Z, Liu W, Liu D, Zhang X, Chen L, Qi L, Chen L, Luo Y, Li Q, Chen P, Wu Q, Zhu X, Guo H
Cell death & disease 2022 Nov 29;13(11):1010
Cell death & disease 2022 Nov 29;13(11):1010
Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors.
Fan Y, Zhang Y, Shi K, Cheng S, Pei D, Shu X
Cell death & disease 2022 Nov 26;13(11):1000
Cell death & disease 2022 Nov 26;13(11):1000
Inhibition of ferroptosis attenuates oligospermia in male Nrf2 knockout mice.
Han P, Wang X, Zhou T, Cheng J, Wang C, Sun F, Zhao X
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Free radical biology & medicine 2022 Nov 20;193(Pt 1):421-429
Salidroside Alleviates Renal Fibrosis in SAMP8 Mice by Inhibiting Ferroptosis.
Yang S, Pei T, Wang L, Zeng Y, Li W, Yan S, Xiao W, Cheng W
Molecules (Basel, Switzerland) 2022 Nov 19;27(22)
Molecules (Basel, Switzerland) 2022 Nov 19;27(22)
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Wang J, Wen J, Ma X, Yang J, Zhang Z, Xie S, Wei S, Jing M, Li H, Lang L, Zhou X, Zhao Y
European journal of pharmacology 2022 Nov 15;935:175331
European journal of pharmacology 2022 Nov 15;935:175331
Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma.
Sun Q, Xu Y, Yuan F, Qi Y, Wang Y, Chen Q, Liu B
Cell & bioscience 2022 May 3;12(1):53
Cell & bioscience 2022 May 3;12(1):53
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood-brain barrier destruction in Alzheimer's disease.
Li J, Li M, Ge Y, Chen J, Ma J, Wang C, Sun M, Wang L, Yao S, Yao C
Cell & bioscience 2022 May 26;12(1):69
Cell & bioscience 2022 May 26;12(1):69
Patulin Induces Acute Kidney Injury in Mice through Autophagy-Ferroptosis Pathway.
Hou Y, Wang S, Jiang L, Sun X, Li J, Wang N, Liu X, Yao X, Zhang C, Deng H, Yang G
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Journal of agricultural and food chemistry 2022 May 25;70(20):6213-6223
Functional role of the SLC7A11-AS1/xCT axis in the development of gastric cancer cisplatin-resistance by a GSH-dependent mechanism.
Luo Y, Xiang W, Liu Z, Yao L, Tang L, Tan W, Ye P, Deng J, Xiao J
Free radical biology & medicine 2022 May 1;184:53-65
Free radical biology & medicine 2022 May 1;184:53-65
Obacunone alleviates ferroptosis during lipopolysaccharide-induced acute lung injury by upregulating Nrf2-dependent antioxidant responses.
Li J, Deng SH, Li J, Li L, Zhang F, Zou Y, Wu DM, Xu Y
Cellular & molecular biology letters 2022 Mar 19;27(1):29
Cellular & molecular biology letters 2022 Mar 19;27(1):29
SSBP1 drives high fructose-induced glomerular podocyte ferroptosis via activating DNA-PK/p53 pathway.
Wu WY, Wang ZX, Li TS, Ding XQ, Liu ZH, Yang J, Fang L, Kong LD
Redox biology 2022 Jun;52:102303
Redox biology 2022 Jun;52:102303
Icariin alleviates uveitis by targeting peroxiredoxin 3 to modulate retinal microglia M1/M2 phenotypic polarization.
Wang G, Li X, Li N, Wang X, He S, Li W, Fan W, Li R, Liu J, Hou S
Redox biology 2022 Jun;52:102297
Redox biology 2022 Jun;52:102297
Action of the Nrf2/ARE signaling pathway on oxidative stress in choroid plexus epithelial cells following lanthanum chloride treatment.
Sun J, Zhang Y, Yan L, Liu S, Wang W, Zhu Y, Wang W, Li S, He B, Wu L, Zhang L
Journal of inorganic biochemistry 2022 Jun;231:111792
Journal of inorganic biochemistry 2022 Jun;231:111792
CEMIP promotes extracellular matrix-detached prostate cancer cell survival by inhibiting ferroptosis.
Liu B, Li X, Wang D, Yu Y, Lu D, Chen L, Lv F, Li Y, Cheng L, Song Y, Xing Y
Cancer science 2022 Jun;113(6):2056-2070
Cancer science 2022 Jun;113(6):2056-2070
Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis.
Yan J, Feng G, Ma L, Chen Z, Jin Q
Journal of orthopaedic surgery and research 2022 Jun 28;17(1):333
Journal of orthopaedic surgery and research 2022 Jun 28;17(1):333
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Liu Y, Ouyang L, Mao C, Chen Y, Li T, Liu N, Wang Z, Lai W, Zhou Y, Cao Y, Liu S, Liang Y, Wang M, Liu S, Chen L, Shi Y, Xiao D, Tao Y
Oncogene 2022 Jul;41(27):3570-3583
Oncogene 2022 Jul;41(27):3570-3583
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ(1-42)-induced Alzheimer's disease mice and glutamate-injured HT22 cells.
Yang S, Xie Z, Pei T, Zeng Y, Xiong Q, Wei H, Wang Y, Cheng W
Chinese medicine 2022 Jul 4;17(1):82
Chinese medicine 2022 Jul 4;17(1):82
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling.
Zhang W, Gong M, Zhang W, Mo J, Zhang S, Zhu Z, Wang X, Zhang B, Qian W, Wu Z, Ma Q, Wang Z
Cell death & disease 2022 Jul 20;13(7):630
Cell death & disease 2022 Jul 20;13(7):630
C8orf76 Modulates Ferroptosis in Liver Cancer via Transcriptionally Up-Regulating SLC7A11.
Li D, Pan J, Zhang Y, Li Y, Jin S, Zhong C, Chen P, Ma J, Hu W, Fan X, Lin H
Cancers 2022 Jul 13;14(14)
Cancers 2022 Jul 13;14(14)
Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism.
Cui Z, Wang H, Li S, Qin T, Shi H, Ma J, Li L, Yu G, Jiang T, Li C
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Journal of pharmacological sciences 2022 Jan;148(1):73-85
Hydrogen sulfide attenuates ferroptosis and stimulates autophagy by blocking mTOR signaling in sepsis-induced acute lung injury.
Li J, Li M, Li L, Ma J, Yao C, Yao S
Molecular immunology 2022 Jan;141:318-327
Molecular immunology 2022 Jan;141:318-327
METTL3 promotes lung adenocarcinoma tumor growth and inhibits ferroptosis by stabilizing SLC7A11 m(6)A modification.
Xu Y, Lv D, Yan C, Su H, Zhang X, Shi Y, Ying K
Cancer cell international 2022 Jan 7;22(1):11
Cancer cell international 2022 Jan 7;22(1):11
RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner.
Sun S, Gao T, Pang B, Su X, Guo C, Zhang R, Pang Q
Cell death & disease 2022 Jan 21;13(1):73
Cell death & disease 2022 Jan 21;13(1):73
Dihydroquercetin suppresses cigarette smoke induced ferroptosis in the pathogenesis of chronic obstructive pulmonary disease by activating Nrf2-mediated pathway.
Liu X, Ma Y, Luo L, Zong D, Li H, Zeng Z, Cui Y, Meng W, Chen Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153894
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Feb;96:153894
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis.
Ni H, Ruan G, Sun C, Yang X, Miao Z, Li J, Chen Y, Qin H, Liu Y, Zheng L, Xing Y, Xi T, Li X
Environmental toxicology 2022 Feb;37(2):192-200
Environmental toxicology 2022 Feb;37(2):192-200
The dual role of p62 in ferroptosis of glioblastoma according to p53 status.
Yuan F, Sun Q, Zhang S, Ye L, Xu Y, Deng G, Xu Z, Zhang S, Liu B, Chen Q
Cell & bioscience 2022 Feb 25;12(1):20
Cell & bioscience 2022 Feb 25;12(1):20
Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury.
He R, Liu B, Xiong R, Geng B, Meng H, Lin W, Hao B, Zhang L, Wang W, Jiang W, Li N, Geng Q
Cell death discovery 2022 Feb 2;8(1):43
Cell death discovery 2022 Feb 2;8(1):43
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
Defective autophagy triggered by arterial cyclic stretch promotes neointimal hyperplasia in vein grafts via the p62/nrf2/slc7a11 signaling pathway.
Chen Y, Bao M, Liu JT, Bao H, Zhang SM, Lou Y, Qi YX
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
Journal of molecular and cellular cardiology 2022 Dec;173:101-114
A multi-omic landscape of steatosis-to-NASH progression.
Xiang L, Li X, Luo Y, Zhou B, Liu Y, Li Y, Wu D, Jia L, Zhu PW, Zheng MH, Wang H, Lu Y
Life metabolism 2022 Dec;1(3):242-257
Life metabolism 2022 Dec;1(3):242-257
Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis.
Yue L, Yang YR, Ma WX, Wang HY, Fan QW, Wang YY, Li C, Wang J, Hu ZM, Wang XF, Li FH, Liu MM, Jin J, Shi C, Wen JG
Molecules (Basel, Switzerland) 2022 Dec 5;27(23)
Molecules (Basel, Switzerland) 2022 Dec 5;27(23)
Anti-Inflammatory Effect of Dimethyl Fumarate Associates with the Inhibition of Thioredoxin Reductase 1 in RAW 264.7 Cells.
Yang R, Sun S, Guo Y, Meng Y, Liu H, Shi M, Guan S, Xu J
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
Molecules (Basel, Switzerland) 2022 Dec 23;28(1)
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
Xie J, Ye Z, Li L, Xia Y, Yuan R, Ruan Y, Zhou X
Molecular medicine reports 2022 Aug;26(2)
Molecular medicine reports 2022 Aug;26(2)
An all-in-one biomimetic iron-small interfering RNA nanoplatform induces ferroptosis for cancer therapy.
Huang S, Le H, Hong G, Chen G, Zhang F, Lu L, Zhang X, Qiu Y, Wang Z, Zhang Q, Ouyang G, Shen J
Acta biomaterialia 2022 Aug;148:244-257
Acta biomaterialia 2022 Aug;148:244-257
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis.
Bao C, Liu C, Liu Q, Hua L, Hu J, Li Z, Xu S
International immunopharmacology 2022 Aug;109:108770
International immunopharmacology 2022 Aug;109:108770
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11.
Hu P, Xu Y, Jiang Y, Huang J, Liu Y, Wang D, Tao T, Sun Z, Liu Y
European journal of pharmacology 2022 Aug 5;928:175093
European journal of pharmacology 2022 Aug 5;928:175093
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination.
Zhang B, Bao W, Zhang S, Chen B, Zhou X, Zhao J, Shi Z, Zhang T, Chen Z, Wang L, Zheng X, Chen G, Wang Y
Cell death & disease 2022 Aug 25;13(8):734
Cell death & disease 2022 Aug 25;13(8):734
Anti-PD-L1 DNAzyme Loaded Photothermal Mn(2+) /Fe(3+) Hybrid Metal-Phenolic Networks for Cyclically Amplified Tumor Ferroptosis-Immunotherapy.
Liu P, Shi X, Peng Y, Hu J, Ding J, Zhou W
Advanced healthcare materials 2022 Apr;11(8):e2102315
Advanced healthcare materials 2022 Apr;11(8):e2102315
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Liang Z, Wu Q, Wang H, Tan J, Wang H, Gou Y, Cao Y, Li Z, Zhang Z
Cell death discovery 2022 Apr 11;8(1):190
Cell death discovery 2022 Apr 11;8(1):190
Construction and Validation of a Combined Ferroptosis and Hypoxia Prognostic Signature for Hepatocellular Carcinoma.
Wen K, Yan Y, Shi J, Hu L, Wang W, Liao H, Li H, Zhu Y, Mao K, Xiao Z
Frontiers in molecular biosciences 2021;8:809672
Frontiers in molecular biosciences 2021;8:809672
Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD.
Zuo Y, Xie J, Li X, Li Y, Thirupathi A, Zhang J, Yu P, Gao G, Chang Y, Shi Z
Oxidative medicine and cellular longevity 2021;2021:9961628
Oxidative medicine and cellular longevity 2021;2021:9961628
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
Ferritinophagy-Mediated ROS Production Contributed to Proliferation Inhibition, Apoptosis, and Ferroptosis Induction in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate Acetate.
Li L, Li H, Li Y, Feng J, Guan D, Zhang Y, Fu Y, Li S, Li C
Oxidative medicine and cellular longevity 2021;2021:5594059
Oxidative medicine and cellular longevity 2021;2021:5594059
Ferritinophagic Flux Was a Driving Force in Determination of Status of EMT, Ferroptosis, and NDRG1 Activation in Action of Mechanism of 2-Pyridylhydrazone Dithiocarbamate S-Acetic Acid.
Li H, Zhou W, Wei H, Li L, Wang X, Li Y, Li S, Li C
Journal of oncology 2021;2021:3015710
Journal of oncology 2021;2021:3015710
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT.
Zheng YW, Miao XY, Xiong L, Chen B, Kong FH, Zhou JJ, Liu ZT, Wen Y, Zhang ZJ, Zou H
Frontiers in pharmacology 2021;12:723488
Frontiers in pharmacology 2021;12:723488
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer.
Sun D, Li YC, Zhang XY
Frontiers in pharmacology 2021;12:681223
Frontiers in pharmacology 2021;12:681223
Dipetidyl peptidase-4 and transferrin receptor serve as prognostic biomarkers for acute myeloid leukemia.
Wei J, Nai GY, Dai Y, Huang XJ, Xiong MY, Yao XY, Huang ZN, Li SN, Zhou WJ, Huang Y, Cheng P, Deng DH
Annals of translational medicine 2021 Sep;9(17):1381
Annals of translational medicine 2021 Sep;9(17):1381
Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity.
Li P, Jiang M, Li K, Li H, Zhou Y, Xiao X, Xu Y, Krishfield S, Lipsky PE, Tsokos GC, Zhang X
Nature immunology 2021 Sep;22(9):1107-1117
Nature immunology 2021 Sep;22(9):1107-1117
Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11.
Wang X, Chen Y, Wang X, Tian H, Wang Y, Jin J, Shan Z, Liu Y, Cai Z, Tong X, Luan Y, Tan X, Luan B, Ge X, Ji H, Jiang X, Wang P
Cancer research 2021 Oct 15;81(20):5217-5229
Cancer research 2021 Oct 15;81(20):5217-5229
Novel function of fluvastatin in attenuating oxidized low-density lipoprotein-induced endothelial cell ferroptosis in a glutathione peroxidase4- and cystine-glutamate antiporter-dependent manner.
Li Q, Liu C, Deng L, Xie E, Yadav N, Tie Y, Cheng Z, Deng J
Experimental and therapeutic medicine 2021 Nov;22(5):1275
Experimental and therapeutic medicine 2021 Nov;22(5):1275
Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion.
Zeng L, Zhou J, Wang X, Zhang Y, Wang M, Su P
Free radical biology & medicine 2021 Nov 20;176:176-188
Free radical biology & medicine 2021 Nov 20;176:176-188
MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis.
Ni H, Qin H, Sun C, Liu Y, Ruan G, Guo Q, Xi T, Xing Y, Zheng L
Stem cell research & therapy 2021 Jun 5;12(1):325
Stem cell research & therapy 2021 Jun 5;12(1):325
Targeted inhibition of Rev-erb-α/β limits ferroptosis to ameliorate folic acid-induced acute kidney injury.
Guo L, Zhang T, Wang F, Chen X, Xu H, Zhou C, Chen M, Yu F, Wang S, Yang D, Wu B
British journal of pharmacology 2021 Jan;178(2):328-345
British journal of pharmacology 2021 Jan;178(2):328-345
A Nuclear Long Non-Coding RNA LINC00618 Accelerates Ferroptosis in a Manner Dependent upon Apoptosis.
Wang Z, Chen X, Liu N, Shi Y, Liu Y, Ouyang L, Tam S, Xiao D, Liu S, Wen F, Tao Y
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):263-274
Molecular therapy : the journal of the American Society of Gene Therapy 2021 Jan 6;29(1):263-274
Lipid Peroxidation, GSH Depletion, and SLC7A11 Inhibition Are Common Causes of EMT and Ferroptosis in A549 Cells, but Different in Specific Mechanisms.
Sun L, Dong H, Zhang W, Wang N, Ni N, Bai X, Liu N
DNA and cell biology 2021 Feb;40(2):172-183
DNA and cell biology 2021 Feb;40(2):172-183
CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathway.
Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, He C, Ma J
Cell proliferation 2021 Dec;54(12):e13142
Cell proliferation 2021 Dec;54(12):e13142
IMCA Induces Ferroptosis Mediated by SLC7A11 through the AMPK/mTOR Pathway in Colorectal Cancer.
Zhang L, Liu W, Liu F, Wang Q, Song M, Yu Q, Tang K, Teng T, Wu D, Wang X, Han W, Li Y
Oxidative medicine and cellular longevity 2020;2020:1675613
Oxidative medicine and cellular longevity 2020;2020:1675613
Susceptibility to erastin-induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.
Hoshino T, Yamakado H, Takahashi R, Matsuzawa SI
FEBS open bio 2020 Sep;10(9):1758-1764
FEBS open bio 2020 Sep;10(9):1758-1764
Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis.
Xu X, Zhang X, Wei C, Zheng D, Lu X, Yang Y, Luo A, Zhang K, Duan X, Wang Y
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2020 Sep 1;152:105450
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma.
Tang B, Zhu J, Li J, Fan K, Gao Y, Cheng S, Kong C, Zheng L, Wu F, Weng Q, Lu C, Ji J
Cell communication and signaling : CCS 2020 Oct 28;18(1):174
Cell communication and signaling : CCS 2020 Oct 28;18(1):174
Discovery of a novel ferroptosis inducer-talaroconvolutin A-killing colorectal cancer cells in vitro and in vivo.
Xia Y, Liu S, Li C, Ai Z, Shen W, Ren W, Yang X
Cell death & disease 2020 Nov 17;11(11):988
Cell death & disease 2020 Nov 17;11(11):988
Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload.
Wang J, Deng B, Liu Q, Huang Y, Chen W, Li J, Zhou Z, Zhang L, Liang B, He J, Chen Z, Yan C, Yang Z, Xian S, Wang L
Cell death & disease 2020 Jul 24;11(7):574
Cell death & disease 2020 Jul 24;11(7):574
Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure.
Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, Sampilvanjil A, Ito J, Nakagawa K, Kuwata H, Hara S, Mizuta K, Sakuma Y, Sata N, Takahashi M
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Cell death & disease 2020 Feb 24;11(2):144
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