32384-1-AP

antibody from Proteintech Group

Targeting: SLC7A11 xCT

Provider product page for 32384-1-AP

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [31]
Comments [0]
Validations [0]

Submit

Product number: 32384-1-AP - Provider product page
Provider: Proteintech Group
Product name: SLC7A11/xCT antibody
Antibody type: Polyclonal
Description: SLC7A11/xCT antibody (Catalog no. 32384-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat and has been validated for the following applications: WB, IF-P, ELISA
Reactivity: Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG

SLC7A11 protein structure - 32384-1-AP shown in red.

Submitted references Processed phellodendri Chinensis cortex attenuates diabetic nephropathy via ferroptosis inhibition through GPX4/SLC7A11/Nrf2/HO-1 signaling pathway.

Zhou Y, Xu G, Ren W, Chen Y, Jiang S, Zhang S, Ge X, Gao H, Zhang F
Journal of natural medicines 2026 May;80(3):776-796

Rhein-Emodin Combination Activates UQCRC1 to Attenuate MPP(+)-Induced Ferroptosis in Dopaminergic Neurons.

Yusun A, Wan H, Li S, Liu Y, Chen H, Sun M, Ding X, Zhang C
Chemistry & biodiversity 2026 Mar;23(3):e02053

Mast Cell-Derived CXCL4: A Key Mediator of Ferroptosis and Cardiac Damage in Septic Cardiomyopathy.

Wei J, Jiang ZY, Ye LF, Lu HX
Immunity, inflammation and disease 2026 Mar;14(3):e70359

Gallium-Doped MXene Nanozymes Protect Liver Through Multi-Death Pathway Blockade and Hepatocyte Regeneration.

Cai X, Deng J, Wang L, Su J, Xian D, Yan Y, Yang X, Wu C, Peng T, Ding Y, Quan G, Wang W, Zhou M, Lu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(14):e09079

Ginsenoside Rh4 Triggers Ferroptosis in Lung Cancer: Targeting KEAP1/NRF2/HO-1 and Remodeling Gut Microbiota for Butyrate-Mediated ATF3 Activation.

Zhu Q, Xu W, Yang G, Gao Y, Zhao Y, Zhao Z, Kang Y, Li S, Zhao L
International journal of molecular sciences 2026 Mar 16;27(6)

Epimedium polysaccharide alleviates adenine-induced oligoasthenozoospermia in mice by inhibiting ferroptosis and inflammation through TLR4/NF-κB and SLC7A11/GPX4 axis.

Tang KY, Ai W, Jiang XC, Xiao M, Zhou YY, Yu XM, Chen SH, Zhao JL
Reproductive biology 2026 Jun;26(2):101203

Mechanism of tectorigenin in promoting thermal burn wound healing via the Nrf2-mediated ferroptosis pathway: Integrated pharmacological and experimental study.

Bashir A, Mei W, Zhang L, Khan MA, Nisar MF, Zhong JL
International journal of biological macromolecules 2026 Jan;339(Pt 1):149890

Eleutheroside E Attenuates Doxorubicin-Induced Cardiotoxicity by Suppressing Ferroptosis Through Activation of the Nrf2/SLC7A11/GPX4 Signaling Pathway.

Sun P, Chen L, Chen X, Zhang X, Guan J, Mo H, Liang Y, Li J, Yan J, Chen D, Zhong C, Yang P
Journal of cardiovascular pharmacology and therapeutics 2026 Jan-Dec;31:10742484261428559

Sodium acetate and sodium butyrate ameliorate postoperative cognitive dysfunction in aged rats by suppressing inflammation and ferroptosis via inhibition of the cGAS-STING signaling pathway.

Zeng KH, Yu LP, Chen Z, Li X
Brain research bulletin 2026 Feb;235:111677

Synergistic microenvironment therapy: a dual-function nanogel of supramolecular collagen ll-mimetic matrix and antioxidant MXene for attenuating intervertebral disc degeneration.

Lyu G, Gao Z, Cao Z, Zhou Q, Chen Y, Yang S, Liang H, Lu X, Li S, Wang X, Sun S, Gao X, Zhou Y, Wu A, Zhou X, Wang X
Journal of nanobiotechnology 2026 Feb 19;24(1)

Acid-sensing ion channel 1a contributes to the calcium/calmodulin-dependent ferroptosis and aggravates intervertebral disc degeneration.

Zhou LP, Wang JQ, Kang L, Hou YX, Yan X, Zhao CH, Jia CY, Zhang HQ, Zhang RJ, Shen CL
Redox report : communications in free radical research 2026 Dec;31(1):2618396

Resveratrol dual efficacy in high-altitude hypoxia and NAFLD: inhibits ferroptosis by modulating key proteins, including HIF-1α, ACSL4, and TfR1.

Zhao M, Mu H, Ji Q, Song J, Zheng F, Liu T, Li W, Wang R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157992

TRIM21 Alleviates Alcoholic Liver Fibrosis by Inhibiting Ferroptosis Through Regulation of IDO1 Ubiquitination.

Zhong W, Luo L, Liu Y, Huang F, Meng Q, Deng G, Li Y, Liu X, Tong G, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Apr 30;40(8):e71773

Alpha-ketoglutarate alleviates Cadmium-induced ferroptosis in association with enhanced mitochondrial function in testes.

Wang X, Dong W, Zhao J, Chen N, Zheng T, Liu Y, Li Q, Ye H, Li H, Xie L
Reproductive toxicology (Elmsford, N.Y.) 2026 Apr 16;143:109249

Unraveling the molecular mechanisms of paraquat toxicity: The interplay of ATF4, ferroptosis, and endoplasmic reticulum stress.

Ke J, Cai Q, Ge X, Zhang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115602

Yishen Qufeng formula mediates ferroptosis to improve renal fibrosis in unilateral ureteral obstruction rats.

Gao J, Wei Y, Zhang W, Yu Y, Ge H, Tian F, Zhou E
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120376

Analysis and verification of potential ferroptosis-related diagnostic markers in the early stage of metabolic dysfunction-associated steatohepatitis.

Li Q, Zhang Q, Ren A, Zhang H, Liu L
Biochemical and biophysical research communications 2025 Sep 12;779:152406

Zearalenone induces intestinal damage and flora disturbance in rats by triggering ferroptosis via the system Xc(-)-GSH-GPX4 signaling pathway.

Huangfu B, Li J, Xu T, Ren X, Zhang R, Chen Y, Wang J, Huang K, He X
Ecotoxicology and environmental safety 2025 Sep 1;302:118600

Mycophenolate mofetil inhibits ferroptosis by boosting autophagy to prevent pulmonary fibrosis.

Liu W, Liu B, Lv C, Li H, Wang Y, Song X, Chen M
Archives of biochemistry and biophysics 2025 Oct;772:110553

TXNIP mediates ferroptosis in a bronchopulmonary dysplasia mouse model by regulating the SLC7A11/GPX4 pathway.

Chen D, Yin F, Yang P, Xia W, Huang Y, Feng Y, Yang L, Lin S, Zhang Q
Scientific reports 2025 Oct 8;15(1):35188

SOCS1 orchestrates ferroptotic renal injury via GPX4 ubiquitination in hyperuricemia.

Zhang R, Fu X, Zhao X, Wang K
Experimental cell research 2025 Oct 1;452(2):114774

Dietary supplementation of Chlorella pyrenoidosa attenuated non-alcoholic fatty liver disease via the NF-κB/ferroptosis axis.

Zhao T, Lu D, Qiu M, Yan B, Fu T
Food & function 2025 Nov 10;16(22):8773-8790

MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis.

Zuo R, Cao B, Kong L, Wang F, Li S, Shan H, Guan J, Kang Q
Journal of orthopaedic translation 2025 Mar;51:337-358

SPATA2/CYLD Pathway-Dependent Deubiquitylation of p53 Promotes Ferroptosis in Rat Heart After Ischaemia/Reperfusion Through Suppression of SLC7A11.

Duan DQ, Li MR, Lu LQ, Yao BF, Huang LL, Luo XJ, Peng J
Heart, lung & circulation 2025 Jul;34(7):719-729

MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway.

Zhang J, He S, Wu K, Wei Y, Li C, Zhu Q, Lian S, Wang L, Wan F, Peng F, Zhang J, Chen Z, Zhang X
Scientific reports 2025 Jul 1;15(1):21199

Pharmacological Activation of GPR68 Attenuates Ferroptosis in Spinal Cord Ischemia/Reperfusion Injury Through PI3K/Akt-Mediated Nrf2 Antioxidant Pathway.

Yang R, Ye J, Wang P, Liu T, Cheng B, Li F
Inflammation 2025 Dec;48(6):4289-4301

Atractylodin inhibits ferroptosis in sepsis‑induced acute gastrointestinal injury via SIRT3/PRDX3.

Hu YX, Chen MQ, Wang JL, Wu T, Zhang HD, Li TT, Gao H, Bai Y
Molecular medicine reports 2025 Dec;32(6)

Assembled Gold Superstructure Triggered Synergistic Apoptosis/Ferroptosis via Combined Photo-Enzyme Therapy.

Chen H, Zheng G, Qin F, Yu Y, Yang H, Mao X
ACS applied materials & interfaces 2025 Dec 17;17(50):68345-68363

Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.

Wu N, Zhang Y, Yin X, Du P, Piao Y, Zhao J, Zhu J, Quan Z, Wu CZ, Jin L, Zhang C
Bioorganic & medicinal chemistry 2025 Dec 1;130:118374

MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.

Liu Y, Hu N, Ai B, Xia H, Li W
BMC cardiovascular disorders 2024 May 30;24(1):286

Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis.

Hong R, Shi Y, Fan Z, Gao Y, Chen H, Pan C
Toxicology 2024 Dec;509:153996

No comments: Submit comment

No validations: Submit validation data