Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA020543 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020543, RRID:AB_1856833
- Product name
- Anti-SHMT2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SHMT2, Gene description: serine hydroxymethyltransferase 2 (mitochondrial), Alternative Gene Names: SHMT, Validated applications: WB, ICC, IHC, Uniprot ID: P34897, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references SHMT2 reduces fatty liver but is necessary for liver inflammation and fibrosis in mice
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation
Immunohistochemical Examination of Trophoblast Syncytialization during Early Placentation in Sheep
Increased formate overflow is a hallmark of oxidative cancer
Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
Differentially expressed proteins in malignant and benign adrenocortical tumors.
Chen G, Zhou G, Zhai L, Bao X, Tiwari N, Li J, Mottillo E, Wang J
Communications Biology 2024;7(1)
Communications Biology 2024;7(1)
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization
Vit O, Talacko P, Musil Z, Hartmann I, Pacak K, Petrak J
Clinical Proteomics 2023;20(1)
Clinical Proteomics 2023;20(1)
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation
Seo H, Melo G, Oliveira R, Franco-Johannsen G, Bazer F, Pohler K, Johnson G
Reproduction 2023;167(2)
Reproduction 2023;167(2)
Immunohistochemical Examination of Trophoblast Syncytialization during Early Placentation in Sheep
Seo H, Bazer F, Burghardt R, Johnson G
International Journal of Molecular Sciences 2019;20(18):4530
International Journal of Molecular Sciences 2019;20(18):4530
Increased formate overflow is a hallmark of oxidative cancer
Meiser J, Schuster A, Pietzke M, Vande Voorde J, Athineos D, Oizel K, Burgos-Barragan G, Wit N, Dhayade S, Morton J, Dornier E, Sumpton D, Mackay G, Blyth K, Patel K, Niclou S, Vazquez A
Nature Communications 2018;9(1)
Nature Communications 2018;9(1)
Serine catabolism is essential to maintain mitochondrial respiration in mammalian cells
Lucas S, Chen G, Aras S, Wang J
Life Science Alliance 2018;1(2):e201800036
Life Science Alliance 2018;1(2):e201800036
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
Kühl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, Filipovska A, Larsson N
eLife 2017;6
eLife 2017;6
Differentially expressed proteins in malignant and benign adrenocortical tumors.
Kjellin H, Johansson H, Höög A, Lehtiö J, Jakobsson PJ, Kjellman M
PloS one 2014;9(2):e87951
PloS one 2014;9(2):e87951
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skeletal muscle tissues using HPA020543 antibody. Corresponding SHMT2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol