11791-1-AP

antibody from Proteintech Group

Targeting: TREM1 CD354, TREM-1

Provider product page for 11791-1-AP

Western blot

ELISA

Immunocytochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [15]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 11791-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11791-1-AP, RRID:AB_2208556
Product name: TREM1 antibody
Antibody type: Polyclonal
Description: TREM1 antibody (Cat. #11791-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

TREM1 protein structure - 11791-1-AP shown in red.

Submitted references Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages.

Dong M, Zhang X, Peng P, Chen Z, Zhang Y, Wan L, Xiang W, Liu G, Guo Y, Xiao Q, Wang B, Guo D, Zhu M, Yu X, Wan F
Cancer letters 2024 May 28;590:216801

Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF-κB pathway.

Guo W, Xu X, Xiao Y, Zhang J, Shen P, Lu X, Fan X
Chinese medicine 2024 Mar 11;19(1):46

H3K4me3-Mediated FOXJ2/SLAMF8 Axis Aggravates Thrombosis and Inflammation in β2GPI/Anti-β2GPI-Treated Monocytes.

Tan Y, Qiao J, Yang S, Liu H, Wang Q, Liu Q, Feng W, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2309140

TREM1(+) tumor-associated macrophages secrete CCL7 to promote hepatocellular carcinoma metastasis.

Huang S, He L, Zhao Y, Wei Y, Wang Q, Gao Y, Jiang X
Journal of cancer research and clinical oncology 2024 Jun 25;150(6):320

TREM1 facilitates the development of gastric cancer through regulating neutrophil extracellular traps-mediated macrophage polarization.

Yu C, Zhou G, Shi Z, Yu L, Zhou X
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2024 Jul;56(7):1237-1247

CGRP is essential for protection against alveolar epithelial cell necroptosis by activating the AMPK/L-OPA1 signaling pathway during acute lung injury.

Jiang HL, Yang HH, Liu YB, Duan JX, Guan XX, Zhang CY, Zhong WJ, Jin L, Li D, Li Q, Zhou Y, Guan CX
Journal of cellular physiology 2024 Feb;239(2):e31169

Increased serum levels of high-mobility group box 1 protein and the location characteristics in the patients of intracranial aneurysms.

Lyu Y, Tu H, Luo J, Wang C, Li A, Zhou Y, Zhao J, Wang H, Hu J
Brain research 2024 Apr 1;1828:148759

Overexpression of TREM1 is Associated with the Immune-Suppressive Microenvironment and Unfavorable Prognosis in Pan-Cancer.

Zhou X, Lin K, Fu L, Liu F, Lin H, Chen Y, Zhuang B, Liang H, Deng Q, Wang Z, Chen W, Luo J, Cao J, Li P
Journal of inflammation research 2023;16:1375-1391

Malaria-derived exosomes exacerbate liver injury during blood stage of Plasmodium berghei infection.

Zhang X, Zhang M, Wang QR, Hou X, Zhou T, Liu J, Wang Q, Liu W, Liu X, Jin X, Liu Z, Huang B
Acta tropica 2023 Mar;239:106815

Candidalysin amplifies the immune inflammatory response in Candida albicans keratitis through the TREM-1/DAP12 pathway.

Hu L, Bai G, Xu Q, Zhao G, Jiang N, Yao H, Liu X, Du Z
International immunopharmacology 2023 Jun;119:110195

Jo-1 Antibodies From Myositis Induce Complement-Dependent Cytotoxicity and TREM-1 Upregulation in Muscle Endothelial Cells.

Honda M, Shimizu F, Sato R, Mizukami Y, Watanabe K, Takeshita Y, Maeda T, Koga M, Kanda T
Neurology(R) neuroimmunology & neuroinflammation 2023 Jul;10(4)

Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway.

Fu A, Qiao F, Feng H, Luo Q
Behavioural brain research 2023 Jul 9;449:114464

Translocated HMGB3 is involved in papillary thyroid cancer progression by activating cytoplasmic TLR3 and transmembrane TREM1.

Zhao Y, Lv HJ, Deng XY, Chen P, Garstka MA, Shi BY, Fu J
Cell cycle (Georgetown, Tex.) 2023 Dec-Dec;22(23-24):2584-2601

A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation.

Yang HH, Duan JX, Liu SK, Xiong JB, Guan XX, Zhong WJ, Sun CC, Zhang CY, Luo XQ, Zhang YF, Chen P, Hammock BD, Hwang SH, Jiang JX, Zhou Y, Guan CX
Theranostics 2020;10(11):4749-4761

Activation of NLRP3 inflammasome up-regulates TREM-1 expression in murine macrophages via HMGB1 and IL-18.

Zhong WJ, Duan JX, Liu T, Yang HH, Guan XX, Zhang CY, Yang JT, Xiong JB, Zhou Y, Guan CX, Li Q
International immunopharmacology 2020 Dec;89(Pt A):107045

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: PC-3 cells were subjected to SDS PAGE followed by western blot with 11791-1-AP(TREM1 antibody) at dilution of 1:400
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using TREM1 antibody 11791-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line