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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB1187P - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse TREM-1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse TREM-1 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse TREM-2B, recombinant human (rh) TREM-1, or rhTREM-2 is observed.
- Reactivity
- Mouse
- Host
- Rat
- Antigen sequence
Q9JKE2- Isotype
- IgG
- Antibody clone number
- 174031
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1.
TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer.
Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival.
Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes.
TREM-1 promotes survival during septic shock in mice.
Yuan Z, Fan X, Staitieh B, Bedi C, Spearman P, Guidot DM, Sadikot RT
Scientific reports 2017 Feb 9;7:42028
Scientific reports 2017 Feb 9;7:42028
TREM-1low is a novel characteristic for tumor-associated macrophages in lung cancer.
Zhang G, Liu H, Huang J, Chen S, Pan X, Huang H, Wang L
Oncotarget 2016 Jun 28;7(26):40508-40517
Oncotarget 2016 Jun 28;7(26):40508-40517
Triggering receptor expressed on myeloid cells 1 (TREM-1)-mediated Bcl-2 induction prolongs macrophage survival.
Yuan Z, Syed MA, Panchal D, Joo M, Colonna M, Brantly M, Sadikot RT
The Journal of biological chemistry 2014 May 23;289(21):15118-29
The Journal of biological chemistry 2014 May 23;289(21):15118-29
Stimulation of the molecule 4-1BB enhances host defense against Listeria monocytogenes infection in mice by inducing rapid infiltration and activation of neutrophils and monocytes.
Lee SC, Ju SA, Sung BH, Heo SK, Cho HR, Lee EA, Kim JD, Lee IH, Park SM, Nguyen QT, Suh JH, Kim BS
Infection and immunity 2009 May;77(5):2168-76
Infection and immunity 2009 May;77(5):2168-76
TREM-1 promotes survival during septic shock in mice.
Gibot S, Massin F, Marcou M, Taylor V, Stidwill R, Wilson P, Singer M, Bellingan G
European journal of immunology 2007 Feb;37(2):456-66
European journal of immunology 2007 Feb;37(2):456-66
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of TREM-1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Gr-1/Ly-6G Alexa Fluor® 405-conjugated Monoclonal Antibody (Catalog # FAB1037V) and either (A) Rat Anti-Mouse TREM-1 PE-conjugated Monoclonal Antibody (Catalog # FAB1187P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
